sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3mgd | ACO | Predicted acetyltransferase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3mgd | ACO | Predicted acetyltransferase | / | 1.000 | |
| 2ou2 | ACO | Histone acetyltransferase KAT5 | / | 0.530 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.509 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.505 | |
| 2y0m | ACO | Histone acetyltransferase KAT8 | / | 0.502 | |
| 1fy7 | COA | Histone acetyltransferase ESA1 | / | 0.499 | |
| 1mja | COA | Histone acetyltransferase ESA1 | / | 0.498 | |
| 3vwe | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.498 | |
| 1e3e | NAI | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.494 | |
| 4kl9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.490 | |
| 1mjb | ACO | Histone acetyltransferase ESA1 | / | 0.489 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.488 | |
| 3vwd | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.488 | |
| 4lx9 | ACO | N-alpha-acetyltransferase | 2.3.1 | 0.488 | |
| 2vzz | SCA | Putative succinyl-CoA transferase Rv0802c | 2.8.3 | 0.487 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.486 | |
| 4hkf | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.486 | |
| 3ohh | 3HH | Beta-secretase 1 | 3.4.23.46 | 0.485 | |
| 4u9y | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.484 | |
| 4aux | XTC | Tetracycline repressor protein class D | / | 0.482 | |
| 2rc4 | ACO | Histone acetyltransferase KAT6A | / | 0.479 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.479 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.478 | |
| 3te5 | NAI | 5'-AMP-activated protein kinase subunit gamma | / | 0.476 | |
| 4iwq | 1FV | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.476 | |
| 4u9z | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.476 | |
| 3dr8 | ACO | L-methionine sulfoximine/L-methionine sulfone acetyltransferase | / | 0.475 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.475 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.474 | |
| 2q4b | NAP | Uncharacterized protein At5g02240 | / | 0.474 | |
| 2x7b | COA | N-alpha-acetyltransferase | 2.3.1 | 0.474 | |
| 2xx9 | 1NF | Glutamate receptor 2 | / | 0.474 | |
| 3tvu | B37 | Acetyl-CoA carboxylase | / | 0.473 | |
| 1wnt | NAP | L-xylulose reductase | 1.1.1.10 | 0.472 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.472 | |
| 5kgh | ACO | Predicted acetyltransferase | / | 0.472 | |
| 3mpj | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.471 | |
| 4bcr | WY1 | Peroxisome proliferator-activated receptor alpha | / | 0.471 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.471 | |
| 1j39 | UPG | DNA beta-glucosyltransferase | / | 0.470 | |
| 3cuk | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.470 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.470 | |
| 3uqd | ATP | ATP-dependent 6-phosphofructokinase isozyme 2 | 2.7.1.11 | 0.470 | |
| 5c88 | COA | N-alpha-acetyltransferase | / | 0.470 | |
| 5dp2 | NAP | CurF | / | 0.470 | |
| 1mj9 | COA | Histone acetyltransferase ESA1 | / | 0.469 | |
| 1nyt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.469 | |
| 2ktd | PUC | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.469 | |
| 4k81 | GTP | GTPase HRas | / | 0.469 | |
| 4l4x | NDP | AmphI | / | 0.469 | |
| 1rbq | KEU | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.468 | |
| 2aa0 | MTP | Adenosine kinase | 2.7.1.20 | 0.468 | |
| 2ar8 | FAD | Flavin-dependent tryptophan halogenase PrnA | 1.14.19.9 | 0.468 | |
| 2om9 | AJA | Peroxisome proliferator-activated receptor gamma | / | 0.468 | |
| 3iah | NAP | Putative oxoacyl-(Acyl carrier protein) reductase | / | 0.468 | |
| 3nxx | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.468 | |
| 2hk9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.467 | |
| 2jn3 | JN3 | Fatty acid-binding protein, liver | / | 0.467 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.467 | |
| 2q2v | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.467 | |
| 3s55 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.467 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.467 | |
| 4fj1 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.467 | |
| 2gvc | FAD | Thiol-specific monooxygenase | 1.14.13 | 0.466 | |
| 2jds | L20 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.466 | |
| 3sx2 | NAD | Uncharacterized protein | / | 0.466 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.465 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.465 | |
| 1ghe | ACO | Acetyltransferase | 2.3.1 | 0.465 | |
| 1k6t | XN1 | Gag-Pol polyprotein | 3.4.23.16 | 0.465 | |
| 3qwf | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.465 | |
| 3to6 | LYS_CMC | Histone acetyltransferase ESA1 | / | 0.465 | |
| 3w8f | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.465 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.465 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.464 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.464 | |
| 4fj0 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.464 | |
| 1byg | STU | Tyrosine-protein kinase CSK | / | 0.463 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.463 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.463 | |
| 2bei | ACO | Diamine acetyltransferase 2 | 2.3.1.57 | 0.463 | |
| 2i4j | DRJ | Peroxisome proliferator-activated receptor gamma | / | 0.463 | |
| 2rcy | NAP | Pyrroline-5-carboxylate reductase | / | 0.463 | |
| 2xpw | OTC | Tetracycline repressor protein class D | / | 0.463 | |
| 3mjh | GTP | Ras-related protein Rab-5A | / | 0.463 | |
| 4b5o | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.463 | |
| 4hwk | NAP | Sepiapterin reductase | 1.1.1.153 | 0.463 | |
| 4is3 | NAD | 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 2 | 1.17.98.1 | 0.463 | |
| 1dxo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.462 | |
| 2ch6 | ADP | N-acetyl-D-glucosamine kinase | 2.7.1.59 | 0.462 | |
| 2uuv | FAD | Alkyldihydroxyacetonephosphate synthase | 2.5.1.26 | 0.462 | |
| 2wsb | NAD | Galactitol dehydrogenase | / | 0.462 | |
| 3il1 | B5D | Glutamate receptor 2 | / | 0.462 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.461 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.461 | |
| 2chx | 090 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.461 | |
| 2eba | FAD | Putative glutaryl-CoA dehydrogenase | / | 0.461 | |
| 3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.461 | |
| 3mdd | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.461 | |
| 4hbg | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.461 | |
| 4iqg | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.461 | |
| 4la1 | FAD | Thioredoxin glutathione reductase | / | 0.461 | |
| 4qq3 | XMP | Inosine-5'-monophosphate dehydrogenase | / | 0.461 | |
| 4tlz | NAP | KtzI | / | 0.461 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.460 | |
| 1o8c | NDP | Probable acrylyl-CoA reductase AcuI | 1.3.1.84 | 0.460 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.460 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.460 | |
| 1y0s | 331 | Peroxisome proliferator-activated receptor delta | / | 0.460 | |
| 2hyd | ADP | Putative multidrug export ATP-binding/permease protein SAV1866 | 3.6.3 | 0.460 | |
| 3b70 | NAP | Enoyl reductase LovC | 1 | 0.460 | |
| 4iah | 1DX | Alr2278 protein | / | 0.460 | |
| 5jsf | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.460 | |
| 2c54 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.459 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.459 | |
| 3clb | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.459 | |
| 4oxy | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.459 | |
| 1nq5 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.458 | |
| 1o0s | NAI | NAD-dependent malic enzyme, mitochondrial | 1.1.1.38 | 0.458 | |
| 2uxp | CLM | HTH-type transcriptional regulator TtgR | / | 0.458 | |
| 2x0r | NAD | Malate dehydrogenase | / | 0.458 | |
| 2y05 | NAP | Prostaglandin reductase 1 | / | 0.458 | |
| 3f8k | COA | Uncharacterized protein | / | 0.458 | |
| 3h86 | AP5 | Adenylate kinase | / | 0.458 | |
| 3mvq | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.458 | |
| 3vdq | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.458 | |
| 4jxr | ACO | Acetyltransferase | / | 0.458 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.457 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.457 | |
| 2uzw | SS4 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.457 | |
| 2wdz | NAD | Galactitol dehydrogenase | / | 0.457 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.457 | |
| 3p19 | NDP | Putative blue fluorescent protein | / | 0.457 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.457 | |
| 5a3b | APR | SIR2 family protein | / | 0.457 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.456 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.456 | |
| 2nq8 | ZID | Enoyl-ACP reductase | / | 0.456 | |
| 2qo7 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.456 | |
| 2xpv | MIY | Tetracycline repressor protein class D | / | 0.456 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.456 | |
| 4an4 | DUD | Putative glycosyl transferase | / | 0.456 | |
| 5kf8 | ACO | Predicted acetyltransferase | / | 0.456 | |
| 2d29 | FAD | Acyl-CoA dehydrogenase | / | 0.455 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.455 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.455 | |
| 2ivp | ATP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.455 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.455 | |
| 2vo7 | M05 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.455 | |
| 2xhd | 7T9 | Glutamate receptor 2 | / | 0.455 | |
| 2y3s | TIR | TamL | / | 0.455 | |
| 3w8e | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.455 | |
| 4b1r | ITC | Tetracycline repressor protein class D | / | 0.455 | |
| 4jji | NAD | Alcohol dehydrogenase class-3 | / | 0.455 | |
| 4yag | NAI | C alpha-dehydrogenase | / | 0.455 | |
| 4z44 | FAD | Flavin-dependent tryptophan halogenase PrnA | 1.14.19.9 | 0.455 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.455 | |
| 1k6c | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.454 | |
| 1lbc | CYZ | Glutamate receptor 2 | / | 0.454 | |
| 1w4z | NAP | Putative ketoacyl reductase | 1.3.1 | 0.454 | |
| 2ard | FDA | Flavin-dependent tryptophan halogenase PrnA | 1.14.19.9 | 0.454 | |
| 2fj1 | CTC | Tetracycline repressor protein class D | / | 0.454 | |
| 2yyl | FAD | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component | 1.14.14.9 | 0.454 | |
| 3fpj | SAM | Uncharacterized protein | / | 0.454 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 3te4 | ACO | Dopamine N-acetyltransferase | / | 0.454 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.454 | |
| 4z63 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.454 | |
| 1pnv | TYD | dTDP-epi-vancosaminyltransferase | 2.4.1.311 | 0.453 | |
| 2o7o | DXT | Tetracycline repressor protein class D | / | 0.453 | |
| 2uxh | QUE | HTH-type transcriptional regulator TtgR | / | 0.453 | |
| 3ac1 | KZI | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.453 | |
| 3cty | FAD | Probable thioredoxin reductase | / | 0.453 | |
| 3cvu | FAD | RE11660p | / | 0.453 | |
| 3etg | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.453 | |
| 3nx4 | NAP | Putative oxidoreductase | / | 0.453 | |
| 3oib | FDA | Putative acyl-CoA dehydrogenase | / | 0.453 | |
| 4gs4 | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.453 | |
| 4l7f | 1V5 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.453 | |
| 4m87 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.453 | |
| 4ynt | FDA | Glucose oxidase, putative | / | 0.453 | |
| 5jsc | FAD | Putative acyl-CoA dehydrogenase | / | 0.453 | |
| 1osv | CHC | Bile acid receptor | / | 0.452 | |
| 2gsd | NAD | Formate dehydrogenase | / | 0.452 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.452 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.452 | |
| 3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 3gkj | HC3 | Niemann-Pick C1 protein | / | 0.452 | |
| 4fdn | FAD | Decaprenylphosphoryl-beta-D-ribose oxidase | / | 0.452 | |
| 4lcj | NAD | C-terminal-binding protein 2 | / | 0.452 | |
| 4nmd | FDA | Bifunctional protein PutA | / | 0.452 | |
| 4o0m | ATP | Circadian clock protein kinase KaiC | 2.7.11.1 | 0.452 | |
| 1g2v | TTP | Glucose-1-phosphate thymidylyltransferase | / | 0.451 | |
| 1x7g | NAP | Putative ketoacyl reductase | 1.3.1 | 0.451 | |
| 2bi8 | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.451 | |
| 2qw0 | 34Z | 4-chlorobenzoyl CoA ligase | / | 0.451 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.451 | |
| 4qi4 | FAD | Cellobiose dehydrogenase | / | 0.451 | |
| 1efp | FAD | Electron transfer flavoprotein subunit alpha | / | 0.450 | |
| 1g4t | FTP | Thiamine-phosphate synthase | / | 0.450 | |
| 1gqt | ACP | Ribokinase | / | 0.450 | |
| 1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.450 | |
| 1zid | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.450 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 2dte | NAI | Glucose 1-dehydrogenase related protein | / | 0.450 | |
| 2fy4 | COA | Choline O-acetyltransferase | 2.3.1.6 | 0.450 | |
| 2i4z | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.450 | |
| 2xpu | TDC | Tetracycline repressor protein class D | / | 0.450 | |
| 2yy7 | NAD | L-threonine dehydrogenase | / | 0.450 | |
| 2ztl | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.450 | |
| 3flk | NAI | Tartrate dehydrogenase/decarboxylase | 1.1.1.93 | 0.450 | |
| 3ndr | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.450 | |
| 3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.450 | |
| 3tsc | NAD | Uncharacterized protein | / | 0.450 | |
| 3ule | C69 | Actin-related protein 3 | / | 0.450 | |
| 4b4w | 9L9 | Bifunctional protein FolD | / | 0.450 | |
| 4r1l | ADP | Phenylacetate-coenzyme A ligase | / | 0.450 | |
| 4yai | NAI | C alpha-dehydrogenase | / | 0.450 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.450 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.450 | |
| 1hvy | D16 | Thymidylate synthase | 2.1.1.45 | 0.449 | |
| 1ju2 | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.449 | |
| 2c0c | NAP | Prostaglandin reductase 3 | 1 | 0.449 | |
| 2c59 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.449 | |
| 2ekl | NAD | D-3-phosphoglycerate dehydrogenase | / | 0.449 | |
| 2fzn | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.449 | |
| 2fzw | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.449 | |
| 2xb5 | I7T | Tetracycline repressor protein class D | / | 0.449 | |
| 2z54 | AB1 | Gag-Pol polyprotein | 3.4.23.16 | 0.449 | |
| 3had | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.449 | |
| 3qls | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 3r3b | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.449 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.449 | |
| 3zbz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.449 | |
| 3zon | IK1 | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.449 | |
| 4bzo | 676 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.449 | |
| 4h8a | NAI | Ureidoglycolate dehydrogenase (NAD(+)) | 1.1.1.350 | 0.449 | |
| 4qi5 | FAD | Cellobiose dehydrogenase | / | 0.449 | |
| 5eai | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.449 | |
| 1ad3 | NAD | Aldehyde dehydrogenase, dimeric NADP-preferring | / | 0.448 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.448 | |
| 1vl8 | NAP | Oxidoreductase, short chain dehydrogenase/reductase family | / | 0.448 | |
| 1ykf | NAP | NADP-dependent isopropanol dehydrogenase | 1.1.1.80 | 0.448 | |
| 2c3q | GTX | Glutathione S-transferase theta-1 | 2.5.1.18 | 0.448 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.448 | |
| 2i4p | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.448 | |
| 2igo | FAD | Pyranose 2-oxidase | / | 0.448 | |
| 2rl1 | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.448 | |
| 2zdu | 446 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.448 | |
| 2zjw | REF | Casein kinase II subunit alpha | 2.7.11.1 | 0.448 | |
| 3r7k | FDA | Probable acyl CoA dehydrogenase | / | 0.448 | |
| 3v2u | ATP | Protein GAL3 | / | 0.448 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.448 | |
| 4hxy | NDP | Plm1 | / | 0.448 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.448 | |
| 4j53 | 1J4 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.448 | |
| 4nxu | ADP | Mitochondrial dynamics protein MID51 | / | 0.448 | |
| 4ri1 | ACO | UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase | 2.3.1.202 | 0.448 | |
| 5e8w | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.448 | |
| 5fkm | TDC | Tetracycline repressor protein class D | / | 0.448 | |
| 1g6k | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.447 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.447 | |
| 1ork | ATC | Tetracycline repressor protein class D | / | 0.447 | |
| 1tj0 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.447 | |
| 2c27 | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.447 | |
| 2f7e | 2EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.447 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.447 | |
| 2r7b | 253 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.447 | |
| 2ztm | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.447 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.447 | |
| 3etd | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.447 | |
| 3lkh | LT6 | Genome polyprotein | 2.7.7.48 | 0.447 | |
| 4h6z | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.447 | |
| 4ku5 | DCC | 3-oxoacyl-[ACP] synthase III | / | 0.447 | |
| 4l8u | 9AZ | Serum albumin | / | 0.447 | |
| 4xgx | ADP | FAD:protein FMN transferase | / | 0.447 | |
| 5a3c | NAD | SIR2 family protein | / | 0.447 | |
| 1cyd | NDP | Carbonyl reductase [NADPH] 2 | 1.1.1.184 | 0.446 | |
| 1gjv | AGS | [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial | 2.7.11.4 | 0.446 | |
| 1lsj | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.446 | |
| 1pr9 | NAP | L-xylulose reductase | 1.1.1.10 | 0.446 | |
| 1qlh | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.446 | |
| 2a4n | COA | Aac(6')-Ii protein | / | 0.446 | |
| 2hb7 | O1C | Vitamin D3 receptor | / | 0.446 | |
| 2ign | FAD | Pyranose 2-oxidase | / | 0.446 | |
| 2q5g | 1FA | Peroxisome proliferator-activated receptor delta | / | 0.446 | |
| 2q7v | FAD | Thioredoxin reductase | / | 0.446 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.446 | |
| 2vnk | FAD | NADPH:ferredoxin reductase | / | 0.446 | |
| 2y4g | TIR | TamL | / | 0.446 | |
| 3bc3 | OPT | Cathepsin L1 | 3.4.22.15 | 0.446 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.446 | |
| 3kyb | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.446 | |
| 3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.446 | |
| 3nl6 | TPS | Uncharacterized protein | / | 0.446 | |
| 3qf9 | NM8 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.446 | |
| 3ruc | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.446 | |
| 3zew | STU | Ephrin type-B receptor 4 | 2.7.10.1 | 0.446 | |
| 4b79 | NAD | Probable short-chain dehydrogenase | / | 0.446 | |
| 4if5 | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.446 | |
| 4kwh | NAP | Reductase homolog | / | 0.446 | |
| 4kxn | 6K6 | 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 | / | 0.446 | |
| 4kzo | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.446 | |
| 4n6h | EJ4 | Delta-type opioid receptor | / | 0.446 | |
| 4r21 | STR | Cytochrome P450 family 17 polypeptide 2 | / | 0.446 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.446 | |
| 5kf9 | ACO | Predicted acetyltransferase | / | 0.446 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.445 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.445 | |
| 1e3w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.445 | |
| 1gpd | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.445 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.445 | |
| 1i5z | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.445 | |
| 1ie3 | NAD | Malate dehydrogenase | / | 0.445 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.445 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.445 | |
| 1mp0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.445 | |
| 1typ | FAD | Trypanothione reductase | 1.8.1.12 | 0.445 | |
| 2chz | 093 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.445 | |
| 2gr1 | FAD | Ferredoxin reductase | / | 0.445 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.445 | |
| 2tct | CTC | Tetracycline repressor protein class D | / | 0.445 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 3a28 | NAD | L-2,3-butanediol dehydrogenase | 1.1.1.76 | 0.445 | |
| 3w0p | ADP | Hygromycin-B 4-O-kinase | 2.7.1.163 | 0.445 | |
| 4abz | T1C | Tetracycline repressor protein class D | / | 0.445 | |
| 4eak | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.445 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.445 | |
| 4i5e | NAP | Alclohol dehydrogenase/short-chain dehydrogenase | / | 0.445 | |
| 4ros | APR | Malate dehydrogenase | / | 0.445 | |
| 4z38 | FMN | MlnA | / | 0.445 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 1s5k | COA | Aminoglycoside N(6')-acetyltransferase type 1 | / | 0.444 | |
| 1xkv | ATP | Phosphoenolpyruvate carboxykinase (ATP) | / | 0.444 | |
| 1zmd | NAI | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.444 | |
| 2dr3 | ADP | UPF0273 protein PH0284 | / | 0.444 | |
| 2nru | T12 | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.444 | |
| 2psw | COA | N-alpha-acetyltransferase 50 | / | 0.444 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 2ywl | FAD | Thioredoxin reductase related protein | / | 0.444 | |
| 3bts | NAD | Galactose/lactose metabolism regulatory protein GAL80 | / | 0.444 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.444 | |
| 3uk6 | ADP | RuvB-like 2 | 3.6.4.12 | 0.444 | |
| 3vt4 | 5YI | Vitamin D3 receptor | / | 0.444 | |
| 4ajp | 88N | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.444 | |
| 4nd3 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.444 | |
| 4nxv | GDP | Mitochondrial dynamics protein MID51 | / | 0.444 | |
| 1cf3 | FAD | Glucose oxidase | 1.1.3.4 | 0.443 | |
| 1gco | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.443 | |
| 1rm5 | NDP | Glyceraldehyde-3-phosphate dehydrogenase A, chloroplastic | 1.2.1.13 | 0.443 | |
| 1uye | PU9 | Heat shock protein HSP 90-alpha | / | 0.443 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.443 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.443 | |
| 2nvb | NAP | NADP-dependent isopropanol dehydrogenase | 1.1.1.80 | 0.443 | |
| 2x3n | FAD | Probable FAD-dependent monooxygenase | / | 0.443 | |
| 2yvw | EPU | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.443 | |
| 2z7h | GG3 | Geranylgeranyl pyrophosphate synthase | / | 0.443 | |
| 4a6n | FAD | TetX family tetracycline inactivation enzyme | / | 0.443 | |
| 4dmm | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.443 | |
| 4eh9 | IRG | Mitogen-activated protein kinase 14 | / | 0.443 | |
| 4hfr | 14M | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.443 | |
| 4pd6 | URI | Nucleoside permease | / | 0.443 | |
| 4zp0 | DXC | Multidrug transporter MdfA | / | 0.443 | |
| 5adv | DBS | Enterochelin uptake periplasmic binding protein | / | 0.443 | |
| 1iy8 | NAD | Levodione reductase | / | 0.442 | |
| 1jip | KTN | 6-deoxyerythronolide B hydroxylase | / | 0.442 | |
| 1jtv | TES | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.442 | |
| 1n06 | ADP | Riboflavin kinase | 2.7.1.26 | 0.442 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 2i4q | UA4 | Renin | 3.4.23.15 | 0.442 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.442 | |
| 2p83 | MR0 | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 2ylw | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.442 | |
| 3ajr | NAD | NDP-sugar epimerase | / | 0.442 | |
| 3cr3 | ADP | PTS-dependent dihydroxyacetone kinase, ADP-binding subunit DhaL | 2.7 | 0.442 | |
| 3crl | ANP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial | 2.7.11.2 | 0.442 | |
| 3gbu | ATP | Uncharacterized sugar kinase PH1459 | 2.7.1 | 0.442 | |
| 3hdm | MMG | Serine/threonine-protein kinase Sgk1 | 2.7.11.1 | 0.442 | |
| 3jqp | A2P | Ferredoxin--NADP reductase, apicoplast | / | 0.442 | |
| 3kgc | LY7 | Glutamate receptor 2 | / | 0.442 | |
| 3ksd | NAD | Glyceraldehyde-3-phosphate dehydrogenase 1 | / | 0.442 | |
| 3lpj | Z75 | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.442 | |
| 3w8d | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.442 | |
| 4cql | NAD | Estradiol 17-beta-dehydrogenase 8 | 1.1.1.62 | 0.442 | |
| 4dpu | AGS | Mevalonate diphosphate decarboxylase | / | 0.442 | |
| 4f07 | FAD | Styrene monooxygenase component 2 | / | 0.442 | |
| 4jnq | FDA | Thioredoxin reductase | / | 0.442 | |
| 4kgm | ATP | Uncharacterized protein | / | 0.442 | |
| 4nu5 | NAD | Phosphonate dehydrogenase | 1.20.1.1 | 0.442 | |
| 4wx1 | FDA | UDP-galactopyranose mutase | / | 0.442 | |
| 5c3j | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.442 | |
| 5ify | UMP | Glucose-1-phosphate thymidylyltransferase | / | 0.442 | |
| 1edo | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase 1, chloroplastic | 1.1.1.100 | 0.441 | |
| 1g0n | NDP | Tetrahydroxynaphthalene reductase | 1.1.1.252 | 0.441 | |
| 1jmh | UMP | Thymidylate synthase | / | 0.441 | |
| 1r6g | 442 | Thyroid hormone receptor beta | / | 0.441 | |
| 1u8f | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.441 | |
| 2uxu | NAR | HTH-type transcriptional regulator TtgR | / | 0.441 | |
| 2y3r | TRK | TamL | / | 0.441 | |
| 3a1c | ACP | Probable copper-exporting P-type ATPase A | 3.6.3.54 | 0.441 | |
| 3i4b | Z48 | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.441 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.441 | |
| 3qfa | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.441 | |
| 3sp6 | IL2 | Peroxisome proliferator-activated receptor alpha | / | 0.441 | |
| 3zc3 | NAP | Ferredoxin--NADP reductase | 1.18.1.2 | 0.441 | |
| 4btj | ATP | Tau-tubulin kinase 1 | 2.7.11.1 | 0.441 | |
| 4ejv | LCL | Transcriptional regulator TcaR | / | 0.441 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.441 | |
| 4jb1 | FAD | UDP-N-acetylenolpyruvoylglucosamine reductase | / | 0.441 | |
| 4n5n | NAP | Acetoacetyl-CoA reductase | 1.1.1.36 | 0.441 | |
| 4xgu | ADP | Putative pachytene checkpoint protein 2 | / | 0.441 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 1efv | FAD | Electron transfer flavoprotein subunit alpha, mitochondrial | / | 0.440 | |
| 1flm | FMN | FMN-binding protein | / | 0.440 | |
| 1gee | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.440 | |
| 1ha3 | MAU | Elongation factor Tu-A | / | 0.440 | |
| 1knr | FAD | L-aspartate oxidase | 1.4.3.16 | 0.440 | |
| 1ma0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.440 | |
| 1pdh | FAS | p-hydroxybenzoate hydroxylase | / | 0.440 | |
| 1u3c | FAD | Cryptochrome-1 | / | 0.440 | |
| 1x7h | NDP | Putative ketoacyl reductase | 1.3.1 | 0.440 | |
| 1yb5 | NAP | Quinone oxidoreductase | 1.6.5.5 | 0.440 | |
| 2cmj | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.440 | |
| 2cvz | NDP | 3-hydroxyisobutyrate dehydrogenase | / | 0.440 | |
| 2e16 | SAH | Diphthine synthase | / | 0.440 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.440 | |
| 3dm6 | 757 | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 3iae | D7K | Benzaldehyde lyase | / | 0.440 | |
| 3syi | FAD | Sulfide-quinone reductase | / | 0.440 | |
| 3t2k | FAD | Sulfide-quinone reductase | / | 0.440 | |
| 4b8w | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.440 | |
| 4gh5 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.440 | |
| 4l2o | NAD | Aldehyde dehydrogenase, dimeric NADP-preferring | / | 0.440 | |
| 4rpg | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.440 | |
| 5emh | NAP | Iridoid synthase | 1.3.1.99 | 0.440 | |
| 5hy5 | FAD | Tryptophan 6-halogenase | / | 0.440 | |
| 5jyd | NAD | Short chain dehydrogenase | / | 0.440 |