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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3iw4LW4Protein kinase C alpha type2.7.11.13

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3iw4LW4Protein kinase C alpha type2.7.11.131.000
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.572
1yi4ADNSerine/threonine-protein kinase pim-12.7.11.10.571
1xwsBI1Serine/threonine-protein kinase pim-12.7.11.10.570
2jedLG8Protein kinase C theta type2.7.11.130.570
2i0ePDSProtein kinase C beta type2.7.11.130.564
2j2iLY4Serine/threonine-protein kinase pim-12.7.11.10.560
4qmxH8HSerine/threonine-protein kinase 242.7.11.10.553
3cy3JN5Serine/threonine-protein kinase pim-12.7.11.10.548
4lm5Q17Serine/threonine-protein kinase pim-12.7.11.10.545
2bikBI1Serine/threonine-protein kinase pim-12.7.11.10.541
3pjcPJCTyrosine-protein kinase JAK32.7.10.20.539
3jxwLXGSerine/threonine-protein kinase pim-12.7.11.10.533
4k0y1OASerine/threonine-protein kinase pim-12.7.11.10.533
4n702HXSerine/threonine-protein kinase pim-12.7.11.10.531
4dtk7LISerine/threonine-protein kinase pim-12.7.11.10.529
4jq8KJ8Epidermal growth factor receptor2.7.10.10.529
4othDRNSerine/threonine-protein kinase N1/0.529
4qmnDB8Serine/threonine-protein kinase 242.7.11.10.529
4achKDIGlycogen synthase kinase-3 beta2.7.11.260.528
5dgzL20Serine/threonine-protein kinase pim-12.7.11.10.526
3c4eC4ESerine/threonine-protein kinase pim-12.7.11.10.523
2o65MYFSerine/threonine-protein kinase pim-12.7.11.10.520
2bilBI1Serine/threonine-protein kinase pim-12.7.11.10.519
4acg6LQGlycogen synthase kinase-3 beta2.7.11.260.519
3uixQ17Serine/threonine-protein kinase pim-12.7.11.10.518
1yi3LY2Serine/threonine-protein kinase pim-12.7.11.10.515
2ow3BIMGlycogen synthase kinase-3 beta2.7.11.260.515
1yhsSTUSerine/threonine-protein kinase pim-12.7.11.10.514
3dcv55ESerine/threonine-protein kinase pim-12.7.11.10.514
4a7cE46Serine/threonine-protein kinase pim-12.7.11.10.512
4qmySTUSerine/threonine-protein kinase 242.7.11.10.512
4gg50J3Hepatocyte growth factor receptor2.7.10.10.511
3r02UNMSerine/threonine-protein kinase pim-12.7.11.10.510
4j97ACPFibroblast growth factor receptor 2/0.510
4gg70J8Hepatocyte growth factor receptor2.7.10.10.509
2gcdSTUSerine/threonine-protein kinase TAO22.7.11.10.508
2r0uM54Serine/threonine-protein kinase Chk12.7.11.10.508
4bchT7ZCyclin-dependent kinase 92.7.11.220.508
4mbl26LSerine/threonine-protein kinase pim-12.7.11.10.508
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.507
2vd5BI8Myotonin-protein kinase2.7.11.10.506
3bgpVX1Serine/threonine-protein kinase pim-12.7.11.10.506
4k181OBSerine/threonine-protein kinase pim-12.7.11.10.506
4gmy0X5Tyrosine-protein kinase JAK2/0.505
4jr3KJREpidermal growth factor receptor2.7.10.10.505
2c3kABOSerine/threonine-protein kinase Chk12.7.11.10.504
3bgzVX3Serine/threonine-protein kinase pim-12.7.11.10.504
3zh8C58Protein kinase C iota type2.7.11.130.503
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.502
4dymIYZActivin receptor type-12.7.11.300.502
3bgqVX2Serine/threonine-protein kinase pim-12.7.11.10.500
4jq7KJQEpidermal growth factor receptor2.7.10.10.500
4afjSJJGlycogen synthase kinase-3 beta2.7.11.260.499
2bdjHETProto-oncogene tyrosine-protein kinase Src2.7.10.20.498
4jrvKJVEpidermal growth factor receptor2.7.10.10.498
3a4pDFQHepatocyte growth factor receptor2.7.10.10.497
4hni16WCasein kinase I isoform epsilon2.7.11.10.497
4qms1N1Serine/threonine-protein kinase 242.7.11.10.497
2hog710Serine/threonine-protein kinase Chk12.7.11.10.496
3dtcVINMitogen-activated protein kinase kinase kinase 92.7.11.250.495
4wboANWRhodopsin kinase/0.495
5e8wSTUTGF-beta receptor type-12.7.11.300.495
1r0eDFNGlycogen synthase kinase-3 beta2.7.11.260.494
2ittAEEEpidermal growth factor receptor2.7.10.10.494
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.494
4n6z2HWSerine/threonine-protein kinase pim-12.7.11.10.494
3blrCPBCyclin-dependent kinase 92.7.11.220.492
3vbq0F5Serine/threonine-protein kinase pim-12.7.11.10.492
4lmuQUESerine/threonine-protein kinase pim-12.7.11.10.492
2xj1XJ1Serine/threonine-protein kinase pim-12.7.11.10.491
4nks2M2Fibroblast growth factor receptor 1/0.491
1eh4IC1Casein kinase I homolog 12.7.11.10.490
1okySTU3-phosphoinositide-dependent protein kinase 12.7.11.10.490
4bznUGXSerine/threonine-protein kinase pim-12.7.11.10.490
1oi9N20Cyclin-dependent kinase 22.7.11.220.489
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.489
2qhm7CSSerine/threonine-protein kinase Chk12.7.11.10.489
2r7b2533-phosphoinositide-dependent protein kinase 12.7.11.10.489
4fnyI3KALK tyrosine kinase receptor2.7.10.10.489
2vn0TDZCytochrome P450 2C8/0.488
3a7hATPSerine/threonine-protein kinase 242.7.11.10.488
3uyt0CKCasein kinase I isoform delta2.7.11.10.488
4bgg844Activin receptor type-12.7.11.300.488
4hyi1AOSerine/threonine-protein kinase Chk12.7.11.10.488
3f883HTGlycogen synthase kinase-3 beta2.7.11.260.487
4b7tCWTGlycogen synthase kinase-3 beta2.7.11.260.487
4qmzB49Serine/threonine-protein kinase 242.7.11.10.487
2of2547Tyrosine-protein kinase Lck2.7.10.20.486
2wgjVGHHepatocyte growth factor receptor2.7.10.10.486
4c02TAKActivin receptor type-12.7.11.300.486
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.486
1zrzBI1Protein kinase C iota type2.7.11.130.485
3ckxSTUSerine/threonine-protein kinase 242.7.11.10.485
4acc7YGGlycogen synthase kinase-3 beta2.7.11.260.485
4qmpDKISerine/threonine-protein kinase 242.7.11.10.485
2c475IDCasein kinase I isoform gamma-2/0.484
3hztJ60Calmodulin-like domain protein kinase isoform 3/0.484
4acdGR9Glycogen synthase kinase-3 beta2.7.11.260.484
1vjy460TGF-beta receptor type-12.7.11.300.483
2h8hH8HProto-oncogene tyrosine-protein kinase Src2.7.10.20.483
3l1sZ92Glycogen synthase kinase-3 beta2.7.11.260.483
3lcdBDYMacrophage colony-stimulating factor 1 receptor2.7.10.10.483
3ncgBK1Calmodulin-domain protein kinase 1, putative/0.483
3t8oATPRhodopsin kinase/0.483
4e4m0NHTyrosine-protein kinase JAK2/0.483
4jia1K3Tyrosine-protein kinase JAK2/0.483
1qpdSTUTyrosine-protein kinase Lck2.7.10.20.482
2xikJ60Serine/threonine-protein kinase 252.7.11.10.482
1pkdUCNCyclin-dependent kinase 22.7.11.220.481
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.481
3a60STURibosomal protein S6 kinase beta-12.7.11.10.481
4gk2L66Ephrin type-A receptor 32.7.10.10.481
4i22IREEpidermal growth factor receptor2.7.10.10.481
1nvrSTUSerine/threonine-protein kinase Chk12.7.11.10.480
2itpAEEEpidermal growth factor receptor2.7.10.10.480
3gubGUBDeath-associated protein kinase 12.7.11.10.480
3oom507Activin receptor type-12.7.11.300.480
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.480
4grb0XGCasein kinase II subunit alpha2.7.11.10.480
4qnaX11Serine/threonine-protein kinase 242.7.11.10.480
1bygSTUTyrosine-protein kinase CSK/0.479
3gb2G3BGlycogen synthase kinase-3 beta2.7.11.260.479
4f630S7Fibroblast growth factor receptor 1/0.479
4ftm1HKSerine/threonine-protein kinase Chk12.7.11.10.479
4g2fC07Ephrin type-A receptor 32.7.10.10.479
4l7sG7KTyrosine-protein kinase ITK/TSK2.7.10.20.479
4xwtU5PRibonuclease J/0.479
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.479
5cvhADPCasein kinase II subunit alpha2.7.11.10.479
2wkmPFYHepatocyte growth factor receptor2.7.10.10.478
3gc9B45Mitogen-activated protein kinase 112.7.11.240.478
4dggI76Proto-oncogene tyrosine-protein kinase Src2.7.10.20.478
3kf7L9GMitogen-activated protein kinase 14/0.477
4yuqKS1Calmodulin-like domain protein kinase/0.477
2objVRVSerine/threonine-protein kinase pim-12.7.11.10.476
3cjgKIMVascular endothelial growth factor receptor 22.7.10.10.476
1nxkSTUMAP kinase-activated protein kinase 22.7.11.10.475
3qf9NM8Serine/threonine-protein kinase pim-12.7.11.10.475
4kb81QNCasein kinase I isoform delta2.7.11.10.475
4nka2K7Fibroblast growth factor receptor 1/0.475
5ar4SB2Receptor-interacting serine/threonine-protein kinase 22.7.11.10.475
1oiyN41Cyclin-dependent kinase 22.7.11.220.474
1u4dDBQActivated CDC42 kinase 1/0.474
2j0j4STFocal adhesion kinase 12.7.10.20.474
2ym44YMSerine/threonine-protein kinase Chk12.7.11.10.474
3a62STURibosomal protein S6 kinase beta-12.7.11.10.474
4erwSTUCyclin-dependent kinase 22.7.11.220.474
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.474
4jib1L6cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.474
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.473
2e9oA58Serine/threonine-protein kinase Chk12.7.11.10.473
2ym6YM6Serine/threonine-protein kinase Chk12.7.11.10.473
3jpv1DRSerine/threonine-protein kinase pim-12.7.11.10.473
3q9xEMOCasein kinase II subunit alpha2.7.11.10.473
4ftkH9KSerine/threonine-protein kinase Chk12.7.11.10.473
2acxANPG protein-coupled receptor kinase 62.7.11.160.472
2ckeIQUDeath-associated protein kinase 2/0.472
2qocANPEphrin type-A receptor 32.7.10.10.472
3el7PD3Proto-oncogene tyrosine-protein kinase Src2.7.10.20.472
3el8PD5Proto-oncogene tyrosine-protein kinase Src2.7.10.20.472
4kba1QMCasein kinase I isoform delta2.7.11.10.472
4l425FIRibosomal protein S6 kinase beta-12.7.11.10.472
4riyADPEpidermal growth factor receptor2.7.10.10.472
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.472
2iw84SPCyclin-dependent kinase 22.7.11.220.471
3c1xCKKHepatocyte growth factor receptor2.7.10.10.471
3cblSTUTyrosine-protein kinase Fes/Fps2.7.10.20.471
3zc5W9ZHepatocyte growth factor receptor2.7.10.10.471
4ez50RSCyclin-dependent kinase 62.7.11.220.471
2qo9ANPEphrin type-A receptor 32.7.10.10.470
3c4xATPRhodopsin kinase/0.470
3c7qXINVascular endothelial growth factor receptor 22.7.10.10.470
3r2b05BMAP kinase-activated protein kinase 22.7.11.10.470
3zep1NXTyrosine-protein kinase JAK32.7.10.20.470
4bzo676Serine/threonine-protein kinase pim-12.7.11.10.470
1m17AQ4Epidermal growth factor receptor2.7.10.10.469
2br1PFPSerine/threonine-protein kinase Chk12.7.11.10.469
2gdo12CSerine/threonine-protein kinase Chk12.7.11.10.469
3du8553Glycogen synthase kinase-3 beta2.7.11.260.469
3zbx6XEHepatocyte growth factor receptor2.7.10.10.469
1bwsNDPGDP-L-fucose synthase/0.468
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.468
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.468
2z2w770Wee1-like protein kinase2.7.10.20.468
3js2VM1Fibroblast growth factor receptor 1/0.468
3sd0TSKGlycogen synthase kinase-3 beta2.7.11.260.468
3vs2VSBTyrosine-protein kinase HCK2.7.10.20.468
4bidIE8Mitogen-activated protein kinase kinase kinase 52.7.11.250.468
4u9aSTUInterleukin-1 receptor-associated kinase 42.7.11.10.468
5ajqDB8Serine/threonine-protein kinase 102.7.11.10.468
1zeoC01Peroxisome proliferator-activated receptor gamma/0.467
2xf04UBSerine/threonine-protein kinase Chk12.7.11.10.467
3e5aVX6Aurora kinase A2.7.11.10.467
3tkh07SSerine/threonine-protein kinase Chk12.7.11.10.467
4ewqMWLMitogen-activated protein kinase 14/0.467
4fstHK4Serine/threonine-protein kinase Chk12.7.11.10.467
4mxxDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.467
4qmlANPSerine/threonine-protein kinase 242.7.11.10.467
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.466
2ivuZD6Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.466
4i41MIXSerine/threonine-protein kinase pim-12.7.11.10.466
5aacVGHALK tyrosine kinase receptor2.7.10.10.466
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.465
3mvl38PMitogen-activated protein kinase 14/0.465
3uagUMAUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.465
3zze6XPHepatocyte growth factor receptor2.7.10.10.465
4aoi4K0Hepatocyte growth factor receptor2.7.10.10.465
4bbe3O4Tyrosine-protein kinase JAK2/0.465
4bqpVMYEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.465
4fic0ULProto-oncogene tyrosine-protein kinase Src2.7.10.20.465
4hyh1AMSerine/threonine-protein kinase Chk12.7.11.10.465
4i0t1B6Tyrosine-protein kinase SYK2.7.10.20.465
4kb81QOCasein kinase I isoform delta2.7.11.10.465
3a99ANPSerine/threonine-protein kinase pim-12.7.11.10.464
3l8p0CEAngiopoietin-1 receptor2.7.10.10.464
3r0tFU9Casein kinase II subunit alpha2.7.11.10.464
3vs7KS1Tyrosine-protein kinase HCK2.7.10.20.464
1h1s4SPCyclin-dependent kinase 22.7.11.220.463
2yfxVGHALK tyrosine kinase receptor2.7.10.10.463
3qlfPD5Proto-oncogene tyrosine-protein kinase Src2.7.10.20.463
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.463
3vrzVRZTyrosine-protein kinase HCK2.7.10.20.463
4deg0JJHepatocyte growth factor receptor2.7.10.10.463
4fsqHK3Serine/threonine-protein kinase Chk12.7.11.10.463
4k1b1OCSerine/threonine-protein kinase pim-12.7.11.10.463
4nc3ERM5-hydroxytryptamine receptor 2B/0.463
1qcfPP1Tyrosine-protein kinase HCK2.7.10.20.462
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.462
3bkbSTUTyrosine-protein kinase Fes/Fps2.7.10.20.462
3bu5ATPInsulin receptor2.7.10.10.462
4hgl0YOCasein kinase I isoform gamma-32.7.11.10.462
4lopSB4Mitogen-activated protein kinase 14/0.462
4xli1N1Abelson tyrosine-protein kinase 22.7.10.20.462
2brhDFWSerine/threonine-protein kinase Chk12.7.11.10.461
2f2cAP9Cyclin-dependent kinase 62.7.11.220.461
2ym5YM5Serine/threonine-protein kinase Chk12.7.11.10.461
4v010LIFibroblast growth factor receptor 1 (Fms-related tyrosine kinase 2, Pfeiffer syndrome), isoform CRA_b/0.461
4xey1N1Tyrosine-protein kinase ABL12.7.10.20.461
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.460
2chlDKICasein kinase I isoform gamma-32.7.11.10.460
2i0y5CNMacrophage colony-stimulating factor 1 receptor2.7.10.10.460
2ym7YM7Serine/threonine-protein kinase Chk12.7.11.10.460
4dfn0K1Tyrosine-protein kinase SYK2.7.10.20.460
4ftcH6KSerine/threonine-protein kinase Chk12.7.11.10.460
1dxoFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.459
1okzUCN3-phosphoinositide-dependent protein kinase 12.7.11.10.459
1wvxBD4Death-associated protein kinase 12.7.11.10.459
1ywrLI9Mitogen-activated protein kinase 14/0.459
2c0tL3GTyrosine-protein kinase HCK2.7.10.20.459
2c3iIYZSerine/threonine-protein kinase pim-12.7.11.10.459
2q0bACPFibroblast growth factor receptor 2/0.459
2wmuZYUSerine/threonine-protein kinase Chk12.7.11.10.459
2xyuQ9GEphrin type-A receptor 42.7.10.10.459
2y6o1N1Ephrin type-A receptor 42.7.10.10.459
2ydiYDISerine/threonine-protein kinase Chk12.7.11.10.459
3c50ADPRhodopsin kinase/0.459
3cqeP91Wee1-like protein kinase2.7.10.20.459
4fob0USALK tyrosine kinase receptor2.7.10.10.459
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.459
4xhgADPUncharacterized protein/0.459
1g5sI17Cyclin-dependent kinase 22.7.11.220.458
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.458
2ghlLIBMitogen-activated protein kinase 14/0.458
3hx4ANPCalmodulin-domain protein kinase 1/0.458
3igoANPCalmodulin-domain protein kinase 1, putative/0.458
4dgnLU2Casein kinase II subunit alpha2.7.11.10.458
4hgt15GCasein kinase I isoform delta2.7.11.10.458
4hvh19RTyrosine-protein kinase JAK32.7.10.20.458
4jqeANPCasein kinase II subunit alpha2.7.11.10.458
5bvw1N1Epithelial discoidin domain-containing receptor 12.7.10.10.458
2pzpACPFibroblast growth factor receptor 2/0.457
2uzlC94Cyclin-dependent kinase 22.7.11.220.457
2wmxZY6Serine/threonine-protein kinase Chk12.7.11.10.457
2wotZZGTGF-beta receptor type-12.7.11.300.457
2xa4AZ5Tyrosine-protein kinase JAK2/0.457
3bqr4RBDeath-associated protein kinase 3/0.457
3vs4VSFTyrosine-protein kinase HCK2.7.10.20.457
4ft0HK9Serine/threonine-protein kinase Chk12.7.11.10.457
4kbk1QGCasein kinase I isoform delta2.7.11.10.457
1uvrBI83-phosphoinositide-dependent protein kinase 12.7.11.10.456
1yvj4STTyrosine-protein kinase JAK32.7.10.20.456
2c6eHPMAurora kinase A2.7.11.10.456
2fgiPD1Fibroblast growth factor receptor 1/0.456
2iw94SPCyclin-dependent kinase 22.7.11.220.456
2j0k4STFocal adhesion kinase 12.7.10.20.456
2vagV25Dual specificity protein kinase CLK12.7.12.10.456
3hllI45Mitogen-activated protein kinase 14/0.456
3mdvCL6Cholesterol 24-hydroxylase/0.456
3umxQ18Serine/threonine-protein kinase pim-12.7.11.10.456
4b8mVX6Aurora kinase B-A2.7.11.10.456
4fsuHK5Serine/threonine-protein kinase Chk12.7.11.10.456
4ftn2HKSerine/threonine-protein kinase Chk12.7.11.10.456
4qo9627Serine/threonine-protein kinase 242.7.11.10.456
2j4z626Aurora kinase A2.7.11.10.455
3a7jADPSerine/threonine-protein kinase 242.7.11.10.455
3kn5ANPRibosomal protein S6 kinase alpha-52.7.11.10.455
3l9lL9LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.455
3mtlFEFCyclin-dependent kinase 162.7.11.220.455
3q3b55EGlycogen synthase kinase-3 beta2.7.11.260.455
3zewSTUEphrin type-B receptor 42.7.10.10.455
4feq0T8Tyrosine-protein kinase receptor TYRO32.7.10.10.455
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.454
1wlvCOAPhenylacetic acid degradation protein PaaI/0.454
2c6tDT5Cyclin-dependent kinase 22.7.11.220.454
2csnCKICasein kinase I homolog 12.7.11.10.454
2gs7ANPEpidermal growth factor receptor2.7.10.10.454
2w9sTOPDihydrofolate reductase type 1 from Tn40031.5.1.30.454
2y46MIVMycinamicin IV hydroxylase/epoxidase/0.454
3ue4DB8Tyrosine-protein kinase ABL12.7.10.20.454
4c61LMMTyrosine-protein kinase JAK2/0.454
4fex0TOAminoglycoside 3'-phosphotransferase AphA1-IAB/0.454
4nk92K5Fibroblast growth factor receptor 1/0.454
4oacADPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.454
5aaaVGHALK tyrosine kinase receptor2.7.10.10.454
2b365PPEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.453
2pwlACPFibroblast growth factor receptor 2/0.453
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.453
4c4h7RODual specificity protein kinase TTK2.7.12.10.453
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.10.453
4mcv29KProto-oncogene tyrosine-protein kinase Src2.7.10.20.453
4mxoDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.453
4qa0SHHHistone deacetylase 83.5.1.980.453
5e8xSTUTGF-beta receptor type-12.7.11.300.453
1q4l679Glycogen synthase kinase-3 beta2.7.11.260.452
2in6839Wee1-like protein kinase2.7.10.20.452
2izrBRKCasein kinase I isoform gamma-32.7.11.10.452
2j0m4STFocal adhesion kinase 12.7.10.20.452
2py3ACPFibroblast growth factor receptor 2/0.452
2wmqZYQSerine/threonine-protein kinase Chk12.7.11.10.452
2xm9LWHSerine/threonine-protein kinase Chk22.7.11.10.452
3gwfFADCyclohexanone monooxygenase/0.452
3i81EBIInsulin-like growth factor 1 receptor2.7.10.10.452
3tea4CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.452
3zrlZRLGlycogen synthase kinase-3 beta2.7.11.260.452
4aacAAVMitogen-activated protein kinase 14/0.452
4flh14KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.452
4g170VNCasein kinase I isoform gamma-32.7.11.10.452
4gih0X5Non-receptor tyrosine-protein kinase TYK22.7.10.20.452
4iarERM5-hydroxytryptamine receptor 1B/0.452
4j1rI5RGlycogen synthase kinase-3 beta2.7.11.260.452
5d12G97Proto-oncogene tyrosine-protein kinase Src2.7.10.20.452
1aq1STUCyclin-dependent kinase 22.7.11.220.451
1ouk084Mitogen-activated protein kinase 14/0.451
2broDF2Serine/threonine-protein kinase Chk12.7.11.10.451
2itqITQEpidermal growth factor receptor2.7.10.10.451
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.451
2vx07X7Ephrin type-B receptor 42.7.10.10.451
2yerTQ1Serine/threonine-protein kinase Chk12.7.11.10.451
3ac3KSHTyrosine-protein kinase Lck2.7.10.20.451
3ag9A02cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.451
3kjsDQ1Bifunctional dihydrofolate reductase-thymidylate synthase/0.451
3pe2E1BCasein kinase II subunit alpha2.7.11.10.451
3tnwF18Cyclin-dependent kinase 22.7.11.220.451
4ansVGHALK tyrosine kinase receptor2.7.10.10.451
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.451
4hge15VTyrosine-protein kinase JAK2/0.451
4hnf16WCasein kinase I isoform delta2.7.11.10.451
5ackATP3-phosphoinositide-dependent protein kinase 12.7.11.10.451
1ir3ANPInsulin receptor2.7.10.10.450
2c3lIDZSerine/threonine-protein kinase Chk12.7.11.10.450
2hk51BMTyrosine-protein kinase HCK2.7.10.20.450
2pz5ACPFibroblast growth factor receptor 2/0.450
2ydkYDKSerine/threonine-protein kinase Chk12.7.11.10.450
2ym3YM3Serine/threonine-protein kinase Chk12.7.11.10.450
3l08ZIGPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.450
3vs6VSHTyrosine-protein kinase HCK2.7.10.20.450
4a06ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.450
4bcqTJFCyclin-dependent kinase 22.7.11.220.450
4ftlH0KSerine/threonine-protein kinase Chk12.7.11.10.450
4ftu7HKSerine/threonine-protein kinase Chk12.7.11.10.450
1e8xATPPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.449
1e9hINRCyclin-dependent kinase 22.7.11.220.449
1gii1PUCyclin-dependent kinase 22.7.11.220.449
1xjdSTUProtein kinase C theta type2.7.11.130.449
2i40BLZCyclin-dependent kinase 22.7.11.220.449
2pvnP63Casein kinase II subunit alpha2.7.11.10.449
2xchCKG3-phosphoinositide-dependent protein kinase 12.7.11.10.449
2zva1N1Tyrosine-protein kinase Lyn2.7.10.20.449
3be9P04Casein kinase II subunit alpha2.7.11.10.449
3nga3NGCasein kinase II subunit alpha2.7.11.10.449
3nww3NWMitogen-activated protein kinase 14/0.449
3zrmZRMGlycogen synthase kinase-3 beta2.7.11.260.449
4bdcODHSerine/threonine-protein kinase Chk22.7.11.10.449
4enxZ20Serine/threonine-protein kinase pim-12.7.11.10.449
4fjyFJYPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.449
4ft9H4KSerine/threonine-protein kinase Chk12.7.11.10.449
4nm0ADPGlycogen synthase kinase-3 beta2.7.11.260.449
2r5tANPSerine/threonine-protein kinase Sgk12.7.11.10.448
3apfBMWPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.448
3cd3STUTyrosine-protein kinase Fes/Fps2.7.10.20.448
3fln3FNMitogen-activated protein kinase 14/0.448
3vjoANPEpidermal growth factor receptor2.7.10.10.448
4aojV4ZHigh affinity nerve growth factor receptor2.7.10.10.448
4b7sQLECytochrome P450 monooxygenase PikC/0.448
4c4jX21Dual specificity protein kinase TTK2.7.12.10.448
4fhk0U0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.448
4gk4L90Ephrin type-A receptor 32.7.10.10.448
4qmtH1NSerine/threonine-protein kinase 242.7.11.10.448
4wkqIREEpidermal growth factor receptor2.7.10.10.448
4yzcSTUSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.448
1o6yACPSerine/threonine-protein kinase PknB2.7.11.10.447
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.447
1tw2ERTCarminomycin 4-O-methyltransferase DnrK2.1.1.2920.447
1xr1ANPSerine/threonine-protein kinase pim-12.7.11.10.447
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.447
2io6330Wee1-like protein kinase2.7.10.20.447
2pvyACPFibroblast growth factor receptor 2/0.447
3b2tM33Fibroblast growth factor receptor 2/0.447
3dt1P40Mitogen-activated protein kinase 14/0.447
3f69XDRSerine/threonine-protein kinase PknB2.7.11.10.447
3ssnMVIMycinamicin VI 2''-O-methyltransferase/0.447
3vt9YI4Vitamin D3 receptor/0.447
4a99MIYTetX family tetracycline inactivation enzyme/0.447
4aa4QC0Mitogen-activated protein kinase 14/0.447
4bcmT7ZCyclin-dependent kinase 22.7.11.220.447
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.447
4fszHK8Serine/threonine-protein kinase Chk12.7.11.10.447
4mq22C4Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.447
4mxyDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.447
4mxzDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.447
1h1r6CPCyclin-dependent kinase 22.7.11.220.446
1r78FMDCyclin-dependent kinase 22.7.11.220.446
1uu8BI13-phosphoinositide-dependent protein kinase 12.7.11.10.446
2c0oL2GTyrosine-protein kinase HCK2.7.10.20.446
2w06FRVCyclin-dependent kinase 22.7.11.220.446
2wouZZFTGF-beta receptor type-12.7.11.300.446
2yitYITSerine/threonine-protein kinase Chk22.7.11.10.446
3a4oSTUTyrosine-protein kinase Lyn2.7.10.20.446
3bfa9ODOdorant binding protein ASP1/0.446
3fklFKLMitogen-activated protein kinase 14/0.446
3ox1695Ribosyldihydronicotinamide dehydrogenase [quinone]/0.446
3w1f1O5Dual specificity protein kinase TTK2.7.12.10.446
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.446
1finATPCyclin-dependent kinase 22.7.11.220.445
1umlFR4Adenosine deaminase3.5.4.40.445
1yolS03Proto-oncogene tyrosine-protein kinase Src2.7.10.20.445
2brgDFYSerine/threonine-protein kinase Chk12.7.11.10.445
2ghmLICMitogen-activated protein kinase 14/0.445
2wihP48Cyclin-dependent kinase 22.7.11.220.445
3fzr3JZProtein-tyrosine kinase 2-beta2.7.10.20.445
3mtfA3FActivin receptor type-12.7.11.300.445
3oqkS52Renin3.4.23.150.445
4ct1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.445
4f640S8Fibroblast growth factor receptor 1/0.445
4ftiH7KSerine/threonine-protein kinase Chk12.7.11.10.445
4fto3HKSerine/threonine-protein kinase Chk12.7.11.10.445
4gw83RASerine/threonine-protein kinase pim-12.7.11.10.445
4o0rX4ZSerine/threonine-protein kinase PAK 12.7.11.10.445
4rrvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.445
3pwhZMAAdenosine receptor A2a/0.445
1jioDEB6-deoxyerythronolide B hydroxylase/0.444
1lp4ANPCasein kinase II subunit alpha2.7.11.10.444
1nq7ARLNuclear receptor ROR-beta/0.444
1zys199Serine/threonine-protein kinase Chk12.7.11.10.444
2ayp43ASerine/threonine-protein kinase Chk12.7.11.10.444
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.444
2e98B29Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.444
2eufLQQCyclin-dependent kinase 62.7.11.220.444
2ivvPP1Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.444
2izt23DCasein kinase I isoform gamma-32.7.11.10.444
2of4979Tyrosine-protein kinase Lck2.7.10.20.444
2x8eX8ESerine/threonine-protein kinase Chk12.7.11.10.444
2ydjYDJSerine/threonine-protein kinase Chk12.7.11.10.444
3l9mL9McAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.444
3mb714ICasein kinase II subunit alpha2.7.11.10.444
3naxMP73-phosphoinositide-dependent protein kinase 12.7.11.10.444
3roc29AMitogen-activated protein kinase 14/0.444
4bi1ZO6Dual specificity protein kinase TTK2.7.12.10.444
4gk3L87Ephrin type-A receptor 32.7.10.10.444
1oiuN76Cyclin-dependent kinase 22.7.11.220.443
1q20PLOSulfotransferase family cytosolic 2B member 12.8.2.20.443
1q3dSTUGlycogen synthase kinase-3 beta2.7.11.260.443
1rfvADPPyridoxal kinase2.7.1.350.443
2balPQAMitogen-activated protein kinase 14/0.443
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.443
2w0jZATSerine/threonine-protein kinase Chk22.7.11.10.443
2wtiWTISerine/threonine-protein kinase Chk22.7.11.10.443
2wugHPK4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase3.7.1.170.443
2xbjXBJSerine/threonine-protein kinase Chk22.7.11.10.443
2y98MIVMycinamicin IV hydroxylase/epoxidase/0.443
2ycsNXPSerine/threonine-protein kinase Chk22.7.11.10.443
3gxlQIGTGF-beta receptor type-12.7.11.300.443
3hdmMMGSerine/threonine-protein kinase Sgk12.7.11.10.443
3s1h56ZCyclin-dependent kinase 22.7.11.220.443
3v5l0G1Tyrosine-protein kinase ITK/TSK2.7.10.20.443
3w2sW2REpidermal growth factor receptor2.7.10.10.443
3wowANPCasein kinase II subunit alpha2.7.11.10.443
4biiPYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.443
4enhFVXCholesterol 24-hydroxylase/0.443
4pkl1GHUncharacterized protein/0.443
1k6tXN1Gag-Pol polyprotein3.4.23.160.442
1ke6LS2Cyclin-dependent kinase 22.7.11.220.442
2c3qGTXGlutathione S-transferase theta-12.5.1.180.442
2dr3ADPUPF0273 protein PH0284/0.442
2pvlP55Casein kinase II subunit alpha2.7.11.10.442
2xviFADPutative flavin-containing monooxygenase/0.442
3bfb9ODPheromone-binding protein ASP1/0.442
4anqVGHALK tyrosine kinase receptor2.7.10.10.442
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.442
4fswHK6Serine/threonine-protein kinase Chk12.7.11.10.442
4gii0X6Non-receptor tyrosine-protein kinase TYK22.7.10.20.442
4gj20XHNon-receptor tyrosine-protein kinase TYK22.7.10.20.442
4iebANPCalmodulin-domain protein kinase 1/0.442
4jlj1NMDeoxycytidine kinase2.7.1.740.442
4k110J9Proto-oncogene tyrosine-protein kinase Src2.7.10.20.442
5auwQUEDeath-associated protein kinase 12.7.11.10.442
5cu6ATPCasein kinase II subunit alpha2.7.11.10.442
1gg5FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.441
1pkfEPDEpothilone C/D epoxidase1.140.441
2hw2RFPRifampin ADP-ribosyl transferase/0.441
2ojg19AMitogen-activated protein kinase 12.7.11.240.441
3bhh5CPCalcium/calmodulin-dependent protein kinase type II subunit beta2.7.11.170.441
3cquCQURAC-alpha serine/threonine-protein kinase2.7.11.10.441
3gc8B45Mitogen-activated protein kinase 112.7.11.240.441
3ibqATPPyridoxal kinase/0.441
3m42HGFMAP kinase-activated protein kinase 22.7.11.10.441
3ma301ISerine/threonine-protein kinase pim-12.7.11.10.441
3q5iANPProtein kinase, putative/0.441
4bi0Z0WDual specificity protein kinase TTK2.7.12.10.441
4hvg19QTyrosine-protein kinase JAK32.7.10.20.441
4loqSB4Mitogen-activated protein kinase 14/0.441
1e7qNAPGDP-L-fucose synthase/0.440
1j3kWRABifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.440
1zz2B11Mitogen-activated protein kinase 14/0.440
2cmwOLPCasein kinase I isoform gamma-12.7.11.10.440
2jamJ60Calcium/calmodulin-dependent protein kinase type 1G2.7.11.170.440
2nq8ZIDEnoyl-ACP reductase/0.440
2x1nX1NCyclin-dependent kinase 22.7.11.220.440
3at3ATKCasein kinase II subunit alpha2.7.11.10.440
3jwm5WBDihydrofolate reductase/0.440
3new3NEMitogen-activated protein kinase 14/0.440
3nlb5BESerine/threonine-protein kinase Chk12.7.11.10.440
3qlg1N1Proto-oncogene tyrosine-protein kinase Src2.7.10.20.440
4bb432WEphrin type-B receptor 42.7.10.10.440
4c62XWWTyrosine-protein kinase JAK2/0.440
4lggVGGProto-oncogene tyrosine-protein kinase Src2.7.10.20.440
4zvmDM2Ribosyldihydronicotinamide dehydrogenase [quinone]/0.440