sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2pan | TDP | Glyoxylate carboligase | 4.1.1.47 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2pan | TDP | Glyoxylate carboligase | 4.1.1.47 | 1.000 | |
| 2q5q | TPW | Indole-3-pyruvate decarboxylase | 4.1.1.74 | 0.560 | |
| 2q5o | TPW | Indole-3-pyruvate decarboxylase | 4.1.1.74 | 0.552 | |
| 5ej9 | TPP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.526 | |
| 5eja | TD6 | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.522 | |
| 5ahk | TPP | Acetolactate synthase II, large subunit | / | 0.520 | |
| 4zp1 | TPP | Pyruvate decarboxylase | 4.1.1.1 | 0.518 | |
| 2ag1 | TPP | Benzaldehyde lyase | / | 0.516 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.511 | |
| 1ozh | HE3 | Acetolactate synthase, catabolic | 2.2.1.6 | 0.509 | |
| 2ihv | TPP | N(2)-(2-carboxyethyl)arginine synthase | / | 0.503 | |
| 4o2b | LOC | Tubulin beta-2B chain | / | 0.502 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.500 | |
| 3lu7 | IPX | Serum albumin | / | 0.494 | |
| 4k9n | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.494 | |
| 2ihu | TP9 | N(2)-(2-carboxyethyl)arginine synthase | / | 0.493 | |
| 2jlc | TPP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.492 | |
| 2hb7 | O1C | Vitamin D3 receptor | / | 0.490 | |
| 3mqe | 416 | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.490 | |
| 4jub | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.490 | |
| 3qm4 | PN0 | Cytochrome P450 2D6 | / | 0.489 | |
| 3wd7 | COA | Acridone synthase | / | 0.489 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.488 | |
| 4ixf | IXF | Dihydrofolate reductase | 1.5.1.3 | 0.487 | |
| 1upc | TPP | N(2)-(2-carboxyethyl)arginine synthase | / | 0.486 | |
| 4juf | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.486 | |
| 2vk8 | TPP | Pyruvate decarboxylase isozyme 1 | / | 0.484 | |
| 1ie9 | VDX | Vitamin D3 receptor | / | 0.483 | |
| 2has | C3O | Vitamin D3 receptor | / | 0.483 | |
| 1ae1 | NAP | Tropinone reductase 1 | / | 0.482 | |
| 2w9s | TOP | Dihydrofolate reductase type 1 from Tn4003 | 1.5.1.3 | 0.482 | |
| 3ey9 | TDP | Pyruvate dehydrogenase [ubiquinone] | 1.2.5.1 | 0.480 | |
| 1ie4 | T44 | Transthyretin | / | 0.479 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.479 | |
| 4a4v | YFD | Peroxisome proliferator-activated receptor gamma | / | 0.479 | |
| 4ia2 | BIV | Vitamin D3 receptor A | / | 0.479 | |
| 5ej7 | TD6 | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.479 | |
| 3w5t | LHP | Vitamin D3 receptor | / | 0.478 | |
| 1tz8 | DES | Transthyretin | / | 0.477 | |
| 3vrt | YS2 | Vitamin D3 receptor | / | 0.477 | |
| 1ovm | TPP | Indole-3-pyruvate decarboxylase | 4.1.1.74 | 0.476 | |
| 2zl9 | VDA | Vitamin D3 receptor | / | 0.476 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.476 | |
| 5eso | TDP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.476 | |
| 1x7h | NDP | Putative ketoacyl reductase | 1.3.1 | 0.475 | |
| 1y4l | SVR | Basic phospholipase A2 homolog 2 | / | 0.475 | |
| 3kpk | FAD | Sulfide-quinone reductase | / | 0.475 | |
| 3qk0 | QK0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.475 | |
| 3vt6 | 5YI | Vitamin D3 receptor | / | 0.475 | |
| 2iht | TPP | N(2)-(2-carboxyethyl)arginine synthase | / | 0.474 | |
| 2c3o | TPP | Pyruvate synthase | / | 0.473 | |
| 3ruk | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.473 | |
| 4e5n | NAD | Phosphonate dehydrogenase | 1.20.1.1 | 0.473 | |
| 4ite | TEY | Vitamin D3 receptor | / | 0.473 | |
| 4kzo | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.473 | |
| 2jla | TPP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.472 | |
| 2q59 | 240 | Peroxisome proliferator-activated receptor gamma | / | 0.472 | |
| 2v3w | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.472 | |
| 3kpz | ZNE | Vitamin D3 receptor | / | 0.472 | |
| 4rup | H97 | Vitamin D3 receptor A | / | 0.472 | |
| 3inw | JZB | Heat shock protein HSP 90-alpha | / | 0.471 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.471 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.471 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.470 | |
| 1i58 | ACP | Chemotaxis protein CheA | 2.7.13.3 | 0.470 | |
| 1s19 | MC9 | Vitamin D3 receptor | / | 0.470 | |
| 1sn5 | T3 | Transthyretin | / | 0.470 | |
| 2pmd | GNP | Translation initiation factor 2 subunit gamma | / | 0.470 | |
| 3mnr | SD1 | Heat shock protein HSP 90-alpha | / | 0.470 | |
| 5esd | TDP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.470 | |
| 1lso | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.469 | |
| 1m2r | MNY | Casein kinase II subunit alpha | 2.7.11.1 | 0.469 | |
| 1mru | AGS | Serine/threonine-protein kinase PknB | 2.7.11.1 | 0.469 | |
| 1um8 | ADP | ATP-dependent Clp protease ATP-binding subunit ClpX | / | 0.469 | |
| 1y9d | TPP | Pyruvate oxidase | 1.2.3.3 | 0.469 | |
| 3bxz | ADP | Protein translocase subunit SecA | / | 0.469 | |
| 3cyl | VIT | Basic phospholipase A2 homolog piratoxin-2 | / | 0.469 | |
| 2j3i | NAP | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.468 | |
| 2pv7 | NAD | T-protein | 1.3.1.12 | 0.468 | |
| 3o6o | 94M | Heat shock protein 83 | / | 0.468 | |
| 4c66 | H4C | Bromodomain-containing protein 4 | / | 0.468 | |
| 4d86 | ADP | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.468 | |
| 4ia1 | BIV | Vitamin D3 receptor A | / | 0.468 | |
| 4o70 | 1QK | Bromodomain-containing protein 4 | / | 0.468 | |
| 1okk | GCP | Signal recognition particle protein | / | 0.467 | |
| 1okk | GCP | Signal recognition particle receptor FtsY | / | 0.467 | |
| 3cs8 | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.467 | |
| 5itz | LOC | Tubulin beta-2B chain | / | 0.467 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.466 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.466 | |
| 1nde | MON | Estrogen receptor beta | / | 0.466 | |
| 3czr | 3CZ | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.466 | |
| 3g5s | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.466 | |
| 3h0a | D30 | Peroxisome proliferator-activated receptor gamma | / | 0.466 | |
| 4nfh | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.466 | |
| 1db1 | VDX | Vitamin D3 receptor | / | 0.465 | |
| 1g4t | FTP | Thiamine-phosphate synthase | / | 0.465 | |
| 1mcz | TDP | Benzoylformate decarboxylase | 4.1.1.7 | 0.465 | |
| 1um0 | FMN | Chorismate synthase | / | 0.465 | |
| 2znn | S44 | Peroxisome proliferator-activated receptor alpha | / | 0.465 | |
| 3stx | BKA | Methylketone synthase I | / | 0.465 | |
| 4bkj | STI | Epithelial discoidin domain-containing receptor 1 | 2.7.10.1 | 0.465 | |
| 4uyf | 73B | Bromodomain-containing protein 2 | / | 0.465 | |
| 1byg | STU | Tyrosine-protein kinase CSK | / | 0.464 | |
| 1rkg | VD1 | Vitamin D3 receptor | / | 0.464 | |
| 1zgy | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.464 | |
| 2c31 | TZD | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.464 | |
| 2y8q | ADP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.464 | |
| 3p3e | 3P3 | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.464 | |
| 3uqd | ATP | ATP-dependent 6-phosphofructokinase isozyme 2 | 2.7.1.11 | 0.464 | |
| 3vt3 | VDX | Vitamin D3 receptor | / | 0.464 | |
| 4hjo | AQ4 | Epidermal growth factor receptor | 2.7.10.1 | 0.464 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.464 | |
| 1fm9 | 570 | Peroxisome proliferator-activated receptor gamma | / | 0.463 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.463 | |
| 1w2x | RCP | Acetyl-CoA carboxylase | / | 0.463 | |
| 2zla | VDB | Vitamin D3 receptor | / | 0.463 | |
| 3ln1 | CEL | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.463 | |
| 4kxl | 6C6 | 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 | / | 0.463 | |
| 4xye | NAD | Formate dehydrogenase | / | 0.463 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.463 | |
| 5ej8 | TD6 | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.463 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.462 | |
| 1qax | HMG | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.88 | 0.462 | |
| 1upa | TPP | N(2)-(2-carboxyethyl)arginine synthase | / | 0.462 | |
| 1yb5 | NAP | Quinone oxidoreductase | 1.6.5.5 | 0.462 | |
| 2c3q | GTX | Glutathione S-transferase theta-1 | 2.5.1.18 | 0.462 | |
| 3a1l | 2CC | Cytochrome P450 | / | 0.462 | |
| 3ruv | ANP | Chaperonin | / | 0.462 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.462 | |
| 5im3 | DTP | Ribonucleoside-diphosphate reductase | / | 0.462 | |
| 4k5y | 1Q5 | Corticotropin-releasing factor receptor 1 | / | 0.462 | |
| 1pvd | TPP | Pyruvate decarboxylase isozyme 1 | / | 0.461 | |
| 1rk3 | VDX | Vitamin D3 receptor | / | 0.461 | |
| 2i4p | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.461 | |
| 2xck | MH4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.461 | |
| 3d0b | SNX | Heat shock protein HSP 90-alpha | / | 0.461 | |
| 3h1j | SMA | Cytochrome b | / | 0.461 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.461 | |
| 4jqh | 1MF | Alr2278 protein | / | 0.461 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.460 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 1sn0 | T44 | Transthyretin | / | 0.460 | |
| 2j4z | 626 | Aurora kinase A | 2.7.11.1 | 0.460 | |
| 2jds | L20 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.460 | |
| 3oe1 | TDL | Pyruvate decarboxylase | 4.1.1.1 | 0.460 | |
| 3w0y | DS4 | Vitamin D3 receptor | / | 0.460 | |
| 4b7d | QLE | Cytochrome P450 monooxygenase PikC | / | 0.460 | |
| 4g1y | 0VO | Vitamin D3 receptor A | / | 0.460 | |
| 1o1v | TCH | Gastrotropin | / | 0.459 | |
| 1om1 | IQA | Casein kinase II subunit alpha | 2.7.11.1 | 0.459 | |
| 2hwr | DRD | Peroxisome proliferator-activated receptor gamma | / | 0.459 | |
| 2i4j | DRJ | Peroxisome proliferator-activated receptor gamma | / | 0.459 | |
| 2o1x | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.459 | |
| 2qk8 | MTX | Dihydrofolate reductase | / | 0.459 | |
| 3cgf | JNF | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.459 | |
| 3t2y | FAD | Sulfide-quinone reductase | / | 0.459 | |
| 4bii | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.459 | |
| 4dhy | S41 | Glucokinase | 2.7.1.2 | 0.459 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.459 | |
| 4ixc | 1JD | Glucokinase | 2.7.1.2 | 0.459 | |
| 4o71 | CPB | Bromodomain-containing protein 4 | / | 0.459 | |
| 1e8z | STU | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.458 | |
| 1o8c | NDP | Probable acrylyl-CoA reductase AcuI | 1.3.1.84 | 0.458 | |
| 2o7o | DXT | Tetracycline repressor protein class D | / | 0.458 | |
| 3fql | 79Z | Genome polyprotein | 2.7.7.48 | 0.458 | |
| 3inm | NDP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.458 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.458 | |
| 3td8 | D2R | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 3vrv | YSD | Vitamin D3 receptor | / | 0.458 | |
| 3zh8 | C58 | Protein kinase C iota type | 2.7.11.13 | 0.458 | |
| 4a6b | QG8 | Gag-Pol polyprotein | 3.4.23.16 | 0.458 | |
| 4at0 | FAD | Possible succinate dehydrogenase | / | 0.458 | |
| 4iwv | 1J9 | Glucokinase | 2.7.1.2 | 0.458 | |
| 4ki8 | ADP | 60 kDa chaperonin | / | 0.458 | |
| 2q5g | 1FA | Peroxisome proliferator-activated receptor delta | / | 0.457 | |
| 3te4 | ACO | Dopamine N-acetyltransferase | / | 0.457 | |
| 3v9v | 21L | Peroxisome proliferator-activated receptor gamma | / | 0.457 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.457 | |
| 4a9o | A9O | Bromodomain-containing protein 2 | / | 0.457 | |
| 4hfm | NAP | 2-alkenal reductase (NADP(+)-dependent) | / | 0.457 | |
| 4jlj | 1NM | Deoxycytidine kinase | 2.7.1.74 | 0.457 | |
| 4ku5 | DCC | 3-oxoacyl-[ACP] synthase III | / | 0.457 | |
| 5br7 | FAD | UDP-galactopyranose mutase | / | 0.457 | |
| 1ppj | ANY | Cytochrome b | / | 0.456 | |
| 1v9n | NDP | Malate dehydrogenase | 1.1.1.37 | 0.456 | |
| 2ca0 | PXI | Cytochrome P450 monooxygenase PikC | / | 0.456 | |
| 2p4y | C03 | Peroxisome proliferator-activated receptor gamma | / | 0.456 | |
| 3a4o | STU | Tyrosine-protein kinase Lyn | 2.7.10.2 | 0.456 | |
| 3a99 | ANP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.456 | |
| 3eya | TDP | Pyruvate dehydrogenase [ubiquinone] | 1.2.5.1 | 0.456 | |
| 3jsu | KA5 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.456 | |
| 3qly | 55V | Uncharacterized protein | / | 0.456 | |
| 4kxn | 6K6 | 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 | / | 0.456 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.456 | |
| 1guf | NDP | Enoyl-[acyl-carrier-protein] reductase 1, mitochondrial | 1.3.1.10 | 0.455 | |
| 1hck | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.455 | |
| 1upb | TPP | N(2)-(2-carboxyethyl)arginine synthase | / | 0.455 | |
| 2ix5 | FAD | Acyl-coenzyme A oxidase 4, peroxisomal | 1.3.3.6 | 0.455 | |
| 2tps | TPS | Thiamine-phosphate synthase | / | 0.455 | |
| 2x7j | TPP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.455 | |
| 3h0s | B38 | Acetyl-CoA carboxylase | / | 0.455 | |
| 3qai | XNN | Ketohexokinase | / | 0.455 | |
| 3r6s | CMP | CRP-like cAMP-activated global transcriptional regulator | / | 0.455 | |
| 4a4w | YFB | Peroxisome proliferator-activated receptor gamma | / | 0.455 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.455 | |
| 4j03 | FVS | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.455 | |
| 4jx1 | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.455 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.455 | |
| 5jqb | IBP | Envelope glycoprotein | / | 0.455 | |
| 1s0z | EB1 | Vitamin D3 receptor | / | 0.454 | |
| 1txi | TX5 | Vitamin D3 receptor | / | 0.454 | |
| 1yre | COA | Uncharacterized protein | / | 0.454 | |
| 2ag0 | TPP | Benzaldehyde lyase | / | 0.454 | |
| 2f5z | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.454 | |
| 2j3k | NAP | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.454 | |
| 2w2l | NAD | D-mandelate dehydrogenase | / | 0.454 | |
| 2xgs | 44P | Uncharacterized protein | / | 0.454 | |
| 2xpu | TDC | Tetracycline repressor protein class D | / | 0.454 | |
| 3oqu | A8S | Abscisic acid receptor PYL9 | / | 0.454 | |
| 3thr | C2F | Glycine N-methyltransferase | 2.1.1.20 | 0.454 | |
| 3uag | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.454 | |
| 3unk | 0BY | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
| 3v9y | 24L | Peroxisome proliferator-activated receptor gamma | / | 0.454 | |
| 4e4q | RRH | Peroxisome proliferator-activated receptor gamma | / | 0.454 | |
| 4jaz | STL | Peroxisome proliferator-activated receptor gamma | / | 0.454 | |
| 5jsc | FAD | Putative acyl-CoA dehydrogenase | / | 0.454 | |
| 1egd | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.453 | |
| 1s5k | COA | Aminoglycoside N(6')-acetyltransferase type 1 | / | 0.453 | |
| 1tw4 | CHD | Fatty acid-binding protein, liver | / | 0.453 | |
| 2j14 | GNI | Peroxisome proliferator-activated receptor delta | / | 0.453 | |
| 2lf1 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 2wot | ZZG | TGF-beta receptor type-1 | 2.7.11.30 | 0.453 | |
| 3ce3 | 1FN | Hepatocyte growth factor receptor | 2.7.10.1 | 0.453 | |
| 3hwx | TPP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.453 | |
| 3lad | FAD | Dihydrolipoyl dehydrogenase | / | 0.453 | |
| 3qrw | NDP | Putative ketoacyl reductase | 1.3.1 | 0.453 | |
| 4k9o | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.453 | |
| 4qi5 | FAD | Cellobiose dehydrogenase | / | 0.453 | |
| 4r8q | ADP | Mitotic checkpoint serine/threonine-protein kinase BUB1 | 2.7.11.1 | 0.453 | |
| 4ryv | ZEA | Protein LlR18A | / | 0.453 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.453 | |
| 5ajq | DB8 | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.453 | |
| 1bwf | ATF | Glycerol kinase | / | 0.452 | |
| 1e90 | MYC | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.452 | |
| 1j4j | ACO | Acetyltransferase | 2.3.1 | 0.452 | |
| 1jio | DEB | 6-deoxyerythronolide B hydroxylase | / | 0.452 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.452 | |
| 1tdo | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.452 | |
| 1vj3 | TAB | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 2cgp | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.452 | |
| 2dbz | NAP | Glyoxylate reductase | 1.1.1.26 | 0.452 | |
| 2hrc | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.452 | |
| 2q7v | FAD | Thioredoxin reductase | / | 0.452 | |
| 2wpw | ACO | Orf14 | / | 0.452 | |
| 2yyi | FAD | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component | 1.14.14.9 | 0.452 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.452 | |
| 3ete | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.452 | |
| 3fl8 | RAR | Dihydrofolate reductase | / | 0.452 | |
| 3flk | NAI | Tartrate dehydrogenase/decarboxylase | 1.1.1.93 | 0.452 | |
| 3q92 | XNB | Ketohexokinase | / | 0.452 | |
| 3sp9 | IL2 | Peroxisome proliferator-activated receptor delta | / | 0.452 | |
| 3tri | NAP | Pyrroline-5-carboxylate reductase | / | 0.452 | |
| 4hjf | C2E | GGDEF family protein | / | 0.452 | |
| 4wa9 | AXI | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.452 | |
| 5k2a | ZMA | Adenosine receptor A2a | / | 0.452 | |
| 1dxo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.451 | |
| 1e1n | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.451 | |
| 1g4s | TPS | Thiamine-phosphate synthase | / | 0.451 | |
| 1jla | TNK | Gag-Pol polyprotein | 2.7.7.49 | 0.451 | |
| 1ra3 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1uye | PU9 | Heat shock protein HSP 90-alpha | / | 0.451 | |
| 1zhw | HC2 | Oxysterol-binding protein homolog 4 | / | 0.451 | |
| 2d4v | NAD | Isocitrate dehydrogenase [NADP] | / | 0.451 | |
| 2daa | DCS | D-alanine aminotransferase | 2.6.1.21 | 0.451 | |
| 2q8s | L92 | Peroxisome proliferator-activated receptor gamma | / | 0.451 | |
| 2w4j | ADP | Death-associated protein kinase 1 | 2.7.11.1 | 0.451 | |
| 2xrw | ANP | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.451 | |
| 3eig | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 3qa2 | XNA | Ketohexokinase | / | 0.451 | |
| 3tdl | 11D | Serum albumin | / | 0.451 | |
| 3w0a | DS5 | Vitamin D3 receptor | / | 0.451 | |
| 3w1w | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.451 | |
| 3zk5 | Z18 | Cytochrome P450 monooxygenase PikC | / | 0.451 | |
| 4g2i | 0VQ | Vitamin D3 receptor | / | 0.451 | |
| 4hse | ADP | Chaperone protein ClpB | / | 0.451 | |
| 4xld | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.451 | |
| 1e4g | ATP | Cell division protein FtsA | / | 0.450 | |
| 1rkh | VD2 | Vitamin D3 receptor | / | 0.450 | |
| 1uy8 | PU5 | Heat shock protein HSP 90-alpha | / | 0.450 | |
| 1wvg | APR | CDP-glucose 4,6-dehydratase | 4.2.1.45 | 0.450 | |
| 2a1t | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.450 | |
| 2i4z | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.450 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.450 | |
| 2wou | ZZF | TGF-beta receptor type-1 | 2.7.11.30 | 0.450 | |
| 2yfe | YFE | Peroxisome proliferator-activated receptor gamma | / | 0.450 | |
| 3ds6 | A17 | Mitogen-activated protein kinase 14 | / | 0.450 | |
| 3stw | 2TD | Methylketone synthase I | / | 0.450 | |
| 4a2b | AGS | Cell division protein FtsA | / | 0.450 | |
| 4e5k | NAD | Phosphonate dehydrogenase | 1.20.1.1 | 0.450 | |
| 4g2h | 0VQ | Vitamin D3 receptor A | / | 0.450 | |
| 4lxh | C1E | Alpha/beta hydrolase fold | / | 0.450 | |
| 4nkv | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.450 | |
| 4pzd | NAD | 3-Hydroxyacyl-CoA dehydrogenase | / | 0.450 | |
| 1e94 | ANP | ATP-dependent protease ATPase subunit HslU | / | 0.449 | |
| 1fm6 | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.449 | |
| 1pn3 | TYD | dTDP-epi-vancosaminyltransferase | 2.4.1.311 | 0.449 | |
| 1pxm | CK5 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 1q4u | 4CA | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.449 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.449 | |
| 1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.449 | |
| 2eba | FAD | Putative glutaryl-CoA dehydrogenase | / | 0.449 | |
| 2p2l | GDP | Ras-related C3 botulinum toxin substrate 1 | / | 0.449 | |
| 2vn0 | TDZ | Cytochrome P450 2C8 | / | 0.449 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.449 | |
| 4dh6 | 0KN | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 4hgs | 15G | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.449 | |
| 4i02 | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.449 | |
| 4jay | FAD | UDP-N-acetylenolpyruvoylglucosamine reductase | / | 0.449 | |
| 4kik | KSA | Inhibitor of nuclear factor kappa-B kinase subunit beta | 2.7.11.10 | 0.449 | |
| 4ly9 | 1YY | Glucokinase regulatory protein | / | 0.449 | |
| 4mih | FAD | Pyranose 2-oxidase | 1.1.3.10 | 0.449 | |
| 4ruo | BIV | Vitamin D3 receptor A | / | 0.449 | |
| 4xgi | NAD | Glutamate dehydrogenase | / | 0.449 | |
| 3pwh | ZMA | Adenosine receptor A2a | / | 0.449 | |
| 1agn | NAD | Alcohol dehydrogenase class 4 mu/sigma chain | 1.1.1.1 | 0.448 | |
| 1cx2 | S58 | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.448 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.448 | |
| 1qpe | PP2 | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.448 | |
| 1uyf | PU1 | Heat shock protein HSP 90-alpha | / | 0.448 | |
| 2har | OCC | Vitamin D3 receptor | / | 0.448 | |
| 2hb8 | MVD | Vitamin D3 receptor | / | 0.448 | |
| 2hfp | NSI | Peroxisome proliferator-activated receptor gamma | / | 0.448 | |
| 2q6s | PLB | Peroxisome proliferator-activated receptor gamma | / | 0.448 | |
| 2vna | NAP | Prostaglandin reductase 2 | 1.3.1.48 | 0.448 | |
| 2yke | YKE | Heat shock protein HSP 90-alpha | / | 0.448 | |
| 3be9 | P04 | Casein kinase II subunit alpha | 2.7.11.1 | 0.448 | |
| 3hz5 | Z64 | Heat shock protein HSP 90-alpha | / | 0.448 | |
| 3inx | JZC | Heat shock protein HSP 90-alpha | / | 0.448 | |
| 3poz | 03P | Epidermal growth factor receptor | 2.7.10.1 | 0.448 | |
| 3t14 | FAD | Sulfide-quinone reductase | / | 0.448 | |
| 3u4u | LNH | Casein kinase II subunit alpha | 2.7.11.1 | 0.448 | |
| 3w5r | LOA | Vitamin D3 receptor | / | 0.448 | |
| 3zc3 | NAP | Ferredoxin--NADP reductase | 1.18.1.2 | 0.448 | |
| 3zm4 | 22T | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.448 | |
| 4em9 | TCE | Peroxisome proliferator-activated receptor gamma | / | 0.448 | |
| 4ge7 | 0K5 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.448 | |
| 4h3c | 0YZ | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.448 | |
| 4nte | FAD | DepH | / | 0.448 | |
| 4pan | GDP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.448 | |
| 4u9y | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.448 | |
| 5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.448 | |
| 3qak | UKA | Adenosine receptor A2a | / | 0.448 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.447 | |
| 1nq7 | ARL | Nuclear receptor ROR-beta | / | 0.447 | |
| 1szm | BI4 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.447 | |
| 1t9g | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.447 | |
| 1u8v | FAD | 4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase | / | 0.447 | |
| 2w93 | TPP | Pyruvate decarboxylase isozyme 1 | / | 0.447 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.447 | |
| 3d8x | FAD | Thioredoxin reductase 1 | 1.8.1.9 | 0.447 | |
| 3dr1 | C5D | Vitamin D3 receptor A | / | 0.447 | |
| 3fco | IIG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.447 | |
| 3ft8 | MOJ | Heat shock protein HSP 90-alpha | / | 0.447 | |
| 3ia4 | MTX | Dihydrofolate reductase | / | 0.447 | |
| 3jqp | A2P | Ferredoxin--NADP reductase, apicoplast | / | 0.447 | |
| 3lki | ATP | Fructokinase | / | 0.447 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.447 | |
| 3vtb | TKA | Vitamin D3 receptor | / | 0.447 | |
| 4a6c | QG9 | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 4i3w | NAD | Aldehyde dehydrogenase (NAD+) | / | 0.447 | |
| 4jib | 1L6 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.447 | |
| 4ku2 | MYA | 3-oxoacyl-[ACP] synthase III | / | 0.447 | |
| 4l9k | EHF | Serum albumin | / | 0.447 | |
| 4mpp | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.447 | |
| 4oj4 | DIF | Peroxisome proliferator-activated receptor gamma | / | 0.447 | |
| 4uym | VOR | 14-alpha sterol demethylase Cyp51B | / | 0.447 | |
| 4xum | IMN | Peroxisome proliferator-activated receptor gamma | / | 0.447 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 1bsv | NDP | GDP-L-fucose synthase | / | 0.446 | |
| 1daj | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1gp2 | GDP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.446 | |
| 1ie8 | KH1 | Vitamin D3 receptor | / | 0.446 | |
| 1iyz | NDP | Probable quinone oxidoreductase | / | 0.446 | |
| 1qpb | TPP | Pyruvate decarboxylase isozyme 1 | / | 0.446 | |
| 1rdt | 570 | Peroxisome proliferator-activated receptor gamma | / | 0.446 | |
| 1reo | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.446 | |
| 1sxj | ADP | Replication factor C subunit 5 | / | 0.446 | |
| 1z6t | ADP | Apoptotic protease-activating factor 1 | / | 0.446 | |
| 2f4b | EHA | Peroxisome proliferator-activated receptor gamma | / | 0.446 | |
| 2hw2 | RFP | Rifampin ADP-ribosyl transferase | / | 0.446 | |
| 2jn3 | JN3 | Fatty acid-binding protein, liver | / | 0.446 | |
| 2qhn | 582 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.446 | |
| 2z3u | CRR | Cytochrome P450 | / | 0.446 | |
| 3ics | COA | Coenzyme A disulfide reductase | / | 0.446 | |
| 3k2h | LYA | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.446 | |
| 3m7r | VDX | Vitamin D3 receptor | / | 0.446 | |
| 3t8x | T8X | T-cell surface glycoprotein CD1b | / | 0.446 | |
| 3zbn | COA | 3-ketoacyl-CoA thiolase-like protein | / | 0.446 | |
| 4f9m | FCM | Peroxisome proliferator-activated receptor gamma | / | 0.446 | |
| 4fkp | LS5 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 4ge4 | 0KE | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.446 | |
| 4hle | 17V | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.446 | |
| 4irn | FAD | AnaB | / | 0.446 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.446 | |
| 4jr3 | KJR | Epidermal growth factor receptor | 2.7.10.1 | 0.446 | |
| 4oae | CLM | Uncharacterized protein | / | 0.446 | |
| 4xf7 | ACP | Carbohydrate/pyrimidine kinase, PfkB family | / | 0.446 | |
| 5eow | FAD | 6-hydroxynicotinate 3-monooxygenase | 1.14.13.114 | 0.446 | |
| 1hnj | MLC | 3-oxoacyl-[acyl-carrier-protein] synthase 3 | / | 0.445 | |
| 1k6c | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 1n4h | REA | Nuclear receptor ROR-beta | / | 0.445 | |
| 1rbm | KT5 | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.445 | |
| 2j8z | NAP | Quinone oxidoreductase PIG3 | 1 | 0.445 | |
| 2q5p | 241 | Peroxisome proliferator-activated receptor gamma | / | 0.445 | |
| 2q61 | SF1 | Peroxisome proliferator-activated receptor gamma | / | 0.445 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.445 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.445 | |
| 3crz | FAD | Ferredoxin--NADP+ reductase | / | 0.445 | |
| 3ge1 | ADP | Glycerol kinase | / | 0.445 | |
| 3ma3 | 01I | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.445 | |
| 3nga | 3NG | Casein kinase II subunit alpha | 2.7.11.1 | 0.445 | |
| 3oib | FDA | Putative acyl-CoA dehydrogenase | / | 0.445 | |
| 3qlf | PD5 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.445 | |
| 3tda | PN0 | Cytochrome P450 2D6 | / | 0.445 | |
| 3vru | YS3 | Vitamin D3 receptor | / | 0.445 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.445 | |
| 4a61 | ANP | Plasmid segregation protein ParM | / | 0.445 | |
| 4a9n | A9N | Bromodomain-containing protein 2 | / | 0.445 | |
| 4aic | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.445 | |
| 4bbf | O19 | Tyrosine-protein kinase JAK2 | / | 0.445 | |
| 4hfr | 14M | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.445 | |
| 4jlc | SU6 | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.445 | |
| 4k11 | 0J9 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.445 | |
| 4l80 | 1VU | Malyl-CoA/beta-methylmalyl-CoA/citramalyl-CoA lyase | 4.1.3.24 | 0.445 | |
| 4l8u | 9AZ | Serum albumin | / | 0.445 | |
| 4lx9 | ACO | N-alpha-acetyltransferase | 2.3.1 | 0.445 | |
| 4xey | 1N1 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.445 | |
| 5bsg | NAP | Pyrroline-5-carboxylate reductase | / | 0.445 | |
| 3rfm | CFF | Adenosine receptor A2a | / | 0.445 | |
| 1ezf | IN0 | Squalene synthase | 2.5.1.21 | 0.444 | |
| 1f4f | TP3 | Thymidylate synthase | / | 0.444 | |
| 1ipe | NDP | Tropinone reductase 2 | 1.1.1.236 | 0.444 | |
| 1kk4 | ACO | Streptogramin A acetyltransferase | 2.3.1 | 0.444 | |
| 1m13 | HYF | Nuclear receptor subfamily 1 group I member 2 | / | 0.444 | |
| 1u4d | DBQ | Activated CDC42 kinase 1 | / | 0.444 | |
| 1uy6 | PU3 | Heat shock protein HSP 90-alpha | / | 0.444 | |
| 1x7g | NAP | Putative ketoacyl reductase | 1.3.1 | 0.444 | |
| 2b7a | IZA | Tyrosine-protein kinase JAK2 | / | 0.444 | |
| 2ceo | T44 | Thyroxine-binding globulin | / | 0.444 | |
| 2hc4 | VDX | Vitamin D3 receptor A | / | 0.444 | |
| 2ic3 | HBY | Gag-Pol polyprotein | 2.7.7.49 | 0.444 | |
| 2pda | TPP | Pyruvate synthase | / | 0.444 | |
| 2w3v | TOP | Dihydrofolate reductase | / | 0.444 | |
| 3cib | 314 | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 3fgo | CZA | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.444 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.444 | |
| 3hub | 469 | Mitogen-activated protein kinase 14 | / | 0.444 | |
| 3ics | ADP | Coenzyme A disulfide reductase | / | 0.444 | |
| 3nug | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.444 | |
| 3sjz | GNP | Translation initiation factor 2 subunit gamma | / | 0.444 | |
| 3sp6 | IL2 | Peroxisome proliferator-activated receptor alpha | / | 0.444 | |
| 3stv | 3HO | Methylketone synthase I | / | 0.444 | |
| 3w4y | FAD | Mitochondrial FAD-linked sulfhydryl oxidase ERV1 | 1.8.3.2 | 0.444 | |
| 4aw3 | MYV | Mycinamicin IV hydroxylase/epoxidase | / | 0.444 | |
| 4fhi | 0S4 | Vitamin D3 receptor A | / | 0.444 | |
| 4gyi | ADP | Uncharacterized protein | / | 0.444 | |
| 4juc | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.444 | |
| 4k1b | 1OC | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.444 | |
| 4kwi | 1TJ | Reductase homolog | / | 0.444 | |
| 4nh8 | 2LC | Heat shock protein HSP 90-alpha | / | 0.444 | |
| 4okt | 198 | Androgen receptor | / | 0.444 | |
| 5eai | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.444 | |
| 5eyp | LOC | Tubulin beta chain | / | 0.444 | |
| 1cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1dhi | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.443 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.443 | |
| 1pmn | 984 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.443 | |
| 1qvr | ANP | Chaperone protein ClpB | / | 0.443 | |
| 1rdt | L79 | Retinoic acid receptor RXR-alpha | / | 0.443 | |
| 1uym | PU3 | Heat shock protein HSP 90-beta | / | 0.443 | |
| 1vjy | 460 | TGF-beta receptor type-1 | 2.7.11.30 | 0.443 | |
| 1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.443 | |
| 2cmv | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.443 | |
| 2igo | FAD | Pyranose 2-oxidase | / | 0.443 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 3a78 | 3EV | Vitamin D3 receptor | / | 0.443 | |
| 3bej | MUF | Bile acid receptor | / | 0.443 | |
| 3dds | 26B | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.443 | |
| 3kgc | LY7 | Glutamate receptor 2 | / | 0.443 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.443 | |
| 3mws | 017 | Pol protein | / | 0.443 | |
| 3nx4 | NAP | Putative oxidoreductase | / | 0.443 | |
| 3oq6 | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.443 | |
| 3qpv | ADP | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 | 2.7.1.105 | 0.443 | |
| 3s79 | ASD | Aromatase | 1.14.14.14 | 0.443 | |
| 3u33 | FAD | Putative acyl-CoA dehydrogenase AidB | 1.3.99 | 0.443 | |
| 3vth | APC | Carbamoyltransferase | / | 0.443 | |
| 3zc6 | VFC | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.443 | |
| 3zux | TCH | Transporter | / | 0.443 | |
| 4a2a | ATP | Cell division protein FtsA | / | 0.443 | |
| 4awp | 99A | Heat shock protein HSP 90-alpha | / | 0.443 | |
| 4bew | CZA | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.443 | |
| 4bqp | VMY | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 4xe6 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 4xuh | SFI | Peroxisome proliferator-activated receptor gamma | / | 0.443 | |
| 1k6p | XN3 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 1pjk | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.442 | |
| 1rc1 | KT3 | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.442 | |
| 1rw8 | 580 | TGF-beta receptor type-1 | 2.7.11.30 | 0.442 | |
| 1uyd | PU8 | Heat shock protein HSP 90-alpha | / | 0.442 | |
| 1zg3 | 2HI | Isoflavone 4'-O-methyltransferase | / | 0.442 | |
| 2cig | 1DG | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 2dte | NAI | Glucose 1-dehydrogenase related protein | / | 0.442 | |
| 2y01 | Y01 | Beta-1 adrenergic receptor | / | 0.442 | |
| 2y30 | SM8 | Putative repressor SimReg2 | / | 0.442 | |
| 3gbk | 2PQ | Peroxisome proliferator-activated receptor gamma | / | 0.442 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.442 | |
| 3hu2 | AGS | Transitional endoplasmic reticulum ATPase | 3.6.4.6 | 0.442 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 4a1z | ADP | Kinesin-like protein KIF11 | / | 0.442 | |
| 4cnj | FAD | L-amino acid oxidase | / | 0.442 | |
| 4ej7 | ATP | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.442 | |
| 4eut | BX7 | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.442 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.442 | |
| 4gyz | D5M | Tyrosyl-DNA phosphodiesterase 2 | 3.1.4 | 0.442 | |
| 4h4q | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.442 | |
| 4i23 | 1C9 | Epidermal growth factor receptor | 2.7.10.1 | 0.442 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.442 | |
| 4nxv | GDP | Mitochondrial dynamics protein MID51 | / | 0.442 | |
| 4o28 | 1QS | Nicotinamide phosphoribosyltransferase | 2.4.2.12 | 0.442 | |
| 4wdb | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.442 | |
| 4wuo | NAD | 3-isopropylmalate dehydrogenase | 1.1.1.85 | 0.442 | |
| 5c8w | PCG | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.442 | |
| 5cdg | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.442 | |
| 1cbs | REA | Cellular retinoic acid-binding protein 2 | / | 0.441 | |
| 1im2 | ADP | ATP-dependent protease ATPase subunit HslU | / | 0.441 | |
| 1lsj | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.441 | |
| 1pf9 | ADP | 60 kDa chaperonin | / | 0.441 | |
| 1t7j | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 1xkk | FMM | Epidermal growth factor receptor | 2.7.10.1 | 0.441 | |
| 2d29 | FAD | Acyl-CoA dehydrogenase | / | 0.441 | |
| 2go4 | TUX | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.441 | |
| 2nru | T12 | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.441 | |
| 2oz6 | CMP | Cyclic AMP receptor-like protein | / | 0.441 | |
| 2prh | 238 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.441 | |
| 2uz1 | TPP | Benzaldehyde lyase | / | 0.441 | |
| 2wpx | ACO | Orf14 | / | 0.441 | |
| 2xcl | ANP | Phosphoribosylamine--glycine ligase | / | 0.441 | |
| 2xhd | 7T9 | Glutamate receptor 2 | / | 0.441 | |
| 2y98 | MIV | Mycinamicin IV hydroxylase/epoxidase | / | 0.441 | |
| 2yyl | FAD | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component | 1.14.14.9 | 0.441 | |
| 2zlc | VDX | Vitamin D3 receptor | / | 0.441 | |
| 3cd2 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 3f8k | COA | Uncharacterized protein | / | 0.441 | |
| 3icr | FAD | Coenzyme A disulfide reductase | / | 0.441 | |
| 3ik6 | HCZ | Glutamate receptor 2 | / | 0.441 | |
| 3mvm | 39P | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 3nd1 | SAH | Precorrin-6A synthase (Deacetylating) | / | 0.441 | |
| 3q0u | LL3 | HTH-type transcriptional regulator EthR | / | 0.441 | |
| 3qcz | ANP | Dihydrofolate synthase/folylpolyglutamate synthase | / | 0.441 | |
| 3tvu | B37 | Acetyl-CoA carboxylase | / | 0.441 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.441 | |
| 4bbe | 3O4 | Tyrosine-protein kinase JAK2 | / | 0.441 | |
| 4c1i | EH9 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.441 | |
| 4egn | TWO | Cytochrome P450 | / | 0.441 | |
| 4f4d | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.441 | |
| 4hbm | 0Y7 | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.441 | |
| 4hy6 | FJ1 | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 4jdr | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.441 | |
| 4jlk | 1NO | Deoxycytidine kinase | 2.7.1.74 | 0.441 | |
| 4ks8 | B49 | Serine/threonine-protein kinase PAK 6 | 2.7.11.1 | 0.441 | |
| 4l3l | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.441 | |
| 4l9q | 9TP | Serum albumin | / | 0.441 | |
| 4x2d | ATP | Fic family protein putative filamentation induced by cAMP protein | / | 0.441 | |
| 4zol | ACP | Tubulin tyrosine ligase | / | 0.441 | |
| 5upj | UIN | Gag-Pol polyprotein | / | 0.441 | |
| 1g69 | TZP | Thiamine-phosphate synthase | / | 0.440 | |
| 1ict | T44 | Transthyretin | / | 0.440 | |
| 1udy | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.440 | |
| 1uu3 | LY4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.440 | |
| 1zdw | FLV | Prenyltransferase | / | 0.440 | |
| 2b0m | 201 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.440 | |
| 2bpw | 1IN | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 2chx | 090 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 2fzw | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.440 | |
| 2gtk | 208 | Peroxisome proliferator-activated receptor gamma | / | 0.440 | |
| 3a8t | ATP | Adenylate isopentenyltransferase | / | 0.440 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.440 | |
| 3gb4 | D3M | DdmC | / | 0.440 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 3n7u | NAD | Formate dehydrogenase, chloroplastic/mitochondrial | / | 0.440 | |
| 3p6p | A6B | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 3pgp | ACO | Uncharacterized protein | / | 0.440 | |
| 3sgt | P09 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | / | 0.440 | |
| 3wfj | NAD | 2-dehydropantoate 2-reductase | / | 0.440 | |
| 4abz | T1C | Tetracycline repressor protein class D | / | 0.440 | |
| 4akn | S5B | Bromodomain-containing protein 2 | / | 0.440 | |
| 4b11 | NHW | Glycylpeptide N-tetradecanoyltransferase | / | 0.440 | |
| 4bcr | WY1 | Peroxisome proliferator-activated receptor alpha | / | 0.440 | |
| 4bl1 | ANP | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.440 | |
| 4eny | J19 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.440 | |
| 4f9f | GDP | Putative glycosyltransferase | / | 0.440 | |
| 4itf | TFY | Vitamin D3 receptor | / | 0.440 | |
| 4k2x | FAD | Polyketide oxygenase/hydroxylase | / | 0.440 | |
| 4lj9 | ACP | Chaperone protein ClpB | / | 0.440 | |
| 4oew | 5IO | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.440 | |
| 4ozn | ATP | Ammonium transporter | / | 0.440 | |
| 5a3b | APR | SIR2 family protein | / | 0.440 |