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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2gcdSTUSerine/threonine-protein kinase TAO22.7.11.1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2gcdSTUSerine/threonine-protein kinase TAO22.7.11.11.000
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.584
4hvh19RTyrosine-protein kinase JAK32.7.10.20.577
1yvj4STTyrosine-protein kinase JAK32.7.10.20.571
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.556
4jia1K3Tyrosine-protein kinase JAK2/0.554
4hvg19QTyrosine-protein kinase JAK32.7.10.20.552
4bibIEOMitogen-activated protein kinase kinase kinase 52.7.11.250.549
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.547
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.543
2i40BLZCyclin-dependent kinase 22.7.11.220.536
4bidIE8Mitogen-activated protein kinase kinase kinase 52.7.11.250.536
4e4m0NHTyrosine-protein kinase JAK2/0.535
4hvi19STyrosine-protein kinase JAK32.7.10.20.533
4acc7YGGlycogen synthase kinase-3 beta2.7.11.260.528
4qmySTUSerine/threonine-protein kinase 242.7.11.10.528
4gmy0X5Tyrosine-protein kinase JAK2/0.527
5e8wSTUTGF-beta receptor type-12.7.11.300.525
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.524
4k1b1OCSerine/threonine-protein kinase pim-12.7.11.10.524
3ckxSTUSerine/threonine-protein kinase 242.7.11.10.522
3lcdBDYMacrophage colony-stimulating factor 1 receptor2.7.10.10.522
4kikKSAInhibitor of nuclear factor kappa-B kinase subunit beta2.7.11.100.522
4yzcSTUSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.521
1e9hINRCyclin-dependent kinase 22.7.11.220.520
2xa4AZ5Tyrosine-protein kinase JAK2/0.520
3zewSTUEphrin type-B receptor 42.7.10.10.520
1aq1STUCyclin-dependent kinase 22.7.11.220.519
2cchATPCyclin-dependent kinase 22.7.11.220.518
4erwSTUCyclin-dependent kinase 22.7.11.220.518
3vs5VSGTyrosine-protein kinase HCK2.7.10.20.517
1u5rATPSerine/threonine-protein kinase TAO22.7.11.10.516
4gih0X5Non-receptor tyrosine-protein kinase TYK22.7.10.20.516
4j95ACPFibroblast growth factor receptor 2/0.515
4qmtH1NSerine/threonine-protein kinase 242.7.11.10.515
1u4dDBQActivated CDC42 kinase 1/0.512
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.512
4eok4SPCyclin-dependent kinase 22.7.11.220.512
1eh4IC1Casein kinase I homolog 12.7.11.10.510
1okySTU3-phosphoinositide-dependent protein kinase 12.7.11.10.510
4jqeANPCasein kinase II subunit alpha2.7.11.10.510
4k110J9Proto-oncogene tyrosine-protein kinase Src2.7.10.20.510
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.510
1m2pHNACasein kinase II subunit alpha2.7.11.10.509
4nj32KDCyclin-dependent kinase 22.7.11.220.509
1h1r6CPCyclin-dependent kinase 22.7.11.220.506
2h96893Mitogen-activated protein kinase 82.7.11.240.506
3bkbSTUTyrosine-protein kinase Fes/Fps2.7.10.20.506
4qmxH8HSerine/threonine-protein kinase 242.7.11.10.506
2vtqLZACyclin-dependent kinase 22.7.11.220.505
4bcnT9NCyclin-dependent kinase 22.7.11.220.505
1xjdSTUProtein kinase C theta type2.7.11.130.504
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.504
2x1nX1NCyclin-dependent kinase 22.7.11.220.504
3cd3STUTyrosine-protein kinase Fes/Fps2.7.10.20.504
3i4bZ48Glycogen synthase kinase-3 beta2.7.11.260.504
4bgg844Activin receptor type-12.7.11.300.504
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.503
3cjgKIMVascular endothelial growth factor receptor 22.7.10.10.503
3f7z34OGlycogen synthase kinase-3 beta2.7.11.260.503
2j0m4STFocal adhesion kinase 12.7.10.20.501
2objVRVSerine/threonine-protein kinase pim-12.7.11.10.501
3zep1NXTyrosine-protein kinase JAK32.7.10.20.501
4i22IREEpidermal growth factor receptor2.7.10.10.501
1fvv107Cyclin-dependent kinase 22.7.11.220.500
1pkdUCNCyclin-dependent kinase 22.7.11.220.500
1q41IXMGlycogen synthase kinase-3 beta2.7.11.260.500
2iw6QQ2Cyclin-dependent kinase 22.7.11.220.500
3lq5SLQCyclin-dependent kinase 92.7.11.220.499
3zh8C58Protein kinase C iota type2.7.11.130.499
4k181OBSerine/threonine-protein kinase pim-12.7.11.10.499
2rioADPSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.498
2wihP48Cyclin-dependent kinase 22.7.11.220.498
1nxkSTUMAP kinase-activated protein kinase 22.7.11.10.497
1u54ACPActivated CDC42 kinase 1/0.497
3mfsANPPeripheral plasma membrane protein CASK2.7.11.10.497
1oi9N20Cyclin-dependent kinase 22.7.11.220.496
4nk92K5Fibroblast growth factor receptor 1/0.495
3uyt0CKCasein kinase I isoform delta2.7.11.10.494
4btkDTQTau-tubulin kinase 12.7.11.10.494
4gii0X6Non-receptor tyrosine-protein kinase TYK22.7.10.20.493
2ivuZD6Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.492
2pvhP19Casein kinase II subunit alpha2.7.11.10.492
3gb2G3BGlycogen synthase kinase-3 beta2.7.11.260.492
3gxlQIGTGF-beta receptor type-12.7.11.300.492
3vs7KS1Tyrosine-protein kinase HCK2.7.10.20.492
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.492
4ic7ANPMitogen-activated protein kinase 72.7.11.240.492
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.492
1g5sI17Cyclin-dependent kinase 22.7.11.220.491
3v5l0G1Tyrosine-protein kinase ITK/TSK2.7.10.20.491
4bbe3O4Tyrosine-protein kinase JAK2/0.491
4bcqTJFCyclin-dependent kinase 22.7.11.220.490
4c61LMMTyrosine-protein kinase JAK2/0.490
4qmnDB8Serine/threonine-protein kinase 242.7.11.10.490
4u9aSTUInterleukin-1 receptor-associated kinase 42.7.11.10.490
5e8xSTUTGF-beta receptor type-12.7.11.300.490
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.489
2ayp43ASerine/threonine-protein kinase Chk12.7.11.10.489
3l8p0CEAngiopoietin-1 receptor2.7.10.10.489
3nynSGVG protein-coupled receptor kinase 62.7.11.160.489
3sd0TSKGlycogen synthase kinase-3 beta2.7.11.260.489
4ckiADNProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.489
2eufLQQCyclin-dependent kinase 62.7.11.220.488
3f69XDRSerine/threonine-protein kinase PknB2.7.11.10.488
3r2b05BMAP kinase-activated protein kinase 22.7.11.10.488
3sheI85MAP kinase-activated protein kinase 32.7.11.10.488
4ix6ADPUncharacterized protein/0.488
2brbPFQSerine/threonine-protein kinase Chk12.7.11.10.487
2ghlLIBMitogen-activated protein kinase 14/0.487
2pvnP63Casein kinase II subunit alpha2.7.11.10.487
3a62STURibosomal protein S6 kinase beta-12.7.11.10.487
3qfvNM7Serine/threonine-protein kinase MRCK beta2.7.11.10.487
4gfo0X2Non-receptor tyrosine-protein kinase TYK22.7.10.20.487
1dawANPCasein kinase II subunit alpha2.7.11.10.486
1qcfPP1Tyrosine-protein kinase HCK2.7.10.20.486
1stcSTUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.486
2b52D42Cyclin-dependent kinase 22.7.11.220.486
2c3kABOSerine/threonine-protein kinase Chk12.7.11.10.486
2ivvPP1Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.486
2ym44YMSerine/threonine-protein kinase Chk12.7.11.10.486
3w2sW2REpidermal growth factor receptor2.7.10.10.486
4nka2K7Fibroblast growth factor receptor 1/0.486
4o0sADNAurora kinase A2.7.11.10.486
1oiuN76Cyclin-dependent kinase 22.7.11.220.485
2fb8215Serine/threonine-protein kinase B-raf2.7.11.10.485
3tnwF18Cyclin-dependent kinase 22.7.11.220.485
4bbfO19Tyrosine-protein kinase JAK2/0.485
1ad5ANPTyrosine-protein kinase HCK2.7.10.20.484
1bygSTUTyrosine-protein kinase CSK/0.484
1h1s4SPCyclin-dependent kinase 22.7.11.220.484
1pmn984Mitogen-activated protein kinase 102.7.11.240.484
2h8hH8HProto-oncogene tyrosine-protein kinase Src2.7.10.20.484
3c50ADPRhodopsin kinase/0.484
3jxwLXGSerine/threonine-protein kinase pim-12.7.11.10.484
3poz03PEpidermal growth factor receptor2.7.10.10.484
3q3b55EGlycogen synthase kinase-3 beta2.7.11.260.484
3w33W19Epidermal growth factor receptor2.7.10.10.484
4acdGR9Glycogen synthase kinase-3 beta2.7.11.260.484
4gub0Y4Casein kinase II subunit alpha2.7.11.10.484
5ajqDB8Serine/threonine-protein kinase 102.7.11.10.484
5ar4SB2Receptor-interacting serine/threonine-protein kinase 22.7.11.10.484
2hy0306Serine/threonine-protein kinase Chk12.7.11.10.483
2pvlP55Casein kinase II subunit alpha2.7.11.10.483
4dit0KDGlycogen synthase kinase-3 beta2.7.11.260.483
4ftu7HKSerine/threonine-protein kinase Chk12.7.11.10.483
4j1rI5RGlycogen synthase kinase-3 beta2.7.11.260.483
1csnATPCasein kinase I homolog 12.7.11.10.482
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.482
2csnCKICasein kinase I homolog 12.7.11.10.482
2in6839Wee1-like protein kinase2.7.10.20.482
2wouZZFTGF-beta receptor type-12.7.11.300.482
3cqeP91Wee1-like protein kinase2.7.10.20.482
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.482
2broDF2Serine/threonine-protein kinase Chk12.7.11.10.481
3hllI45Mitogen-activated protein kinase 14/0.481
3rkb12ZCyclin-dependent kinase 22.7.11.220.481
3uixQ17Serine/threonine-protein kinase pim-12.7.11.10.481
3zc6VFCTyrosine-protein kinase JAK32.7.10.20.481
4ez50RSCyclin-dependent kinase 62.7.11.220.481
3kn5ANPRibosomal protein S6 kinase alpha-52.7.11.10.480
3uli1N3Cyclin-dependent kinase 22.7.11.220.480
4achKDIGlycogen synthase kinase-3 beta2.7.11.260.480
4afjSJJGlycogen synthase kinase-3 beta2.7.11.260.480
4f630S7Fibroblast growth factor receptor 1/0.480
4j97ACPFibroblast growth factor receptor 2/0.480
4riyADPEpidermal growth factor receptor2.7.10.10.480
5drdATPAurora kinase A2.7.11.10.480
2wotZZGTGF-beta receptor type-12.7.11.300.479
3ezrEZRCyclin-dependent kinase 22.7.11.220.479
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.478
3a99ANPSerine/threonine-protein kinase pim-12.7.11.10.478
5e8ySTUTGF-beta receptor type-22.7.11.300.478
1q3wATUGlycogen synthase kinase-3 beta2.7.11.260.477
1zys199Serine/threonine-protein kinase Chk12.7.11.10.477
3t8oATPRhodopsin kinase/0.477
3w32W32Epidermal growth factor receptor2.7.10.10.477
4gj20XHNon-receptor tyrosine-protein kinase TYK22.7.10.20.477
1snuSTUTyrosine-protein kinase ITK/TSK2.7.10.20.476
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.476
2uzdC85Cyclin-dependent kinase 22.7.11.220.476
3l1sZ92Glycogen synthase kinase-3 beta2.7.11.260.476
3vs2VSBTyrosine-protein kinase HCK2.7.10.20.476
4anmWULCasein kinase II subunit alpha2.7.11.10.476
4jrvKJVEpidermal growth factor receptor2.7.10.10.476
1m2qMNXCasein kinase II subunit alpha2.7.11.10.475
1xkkFMMEpidermal growth factor receptor2.7.10.10.475
2ckeIQUDeath-associated protein kinase 2/0.475
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.475
3hztJ60Calmodulin-like domain protein kinase isoform 3/0.475
3mtfA3FActivin receptor type-12.7.11.300.475
4ftiH7KSerine/threonine-protein kinase Chk12.7.11.10.475
4hni16WCasein kinase I isoform epsilon2.7.11.10.475
4im2BX7Serine/threonine-protein kinase TBK12.7.11.10.475
1fm4DXCMajor pollen allergen Bet v 1-L/0.474
1mq4ADPAurora kinase A2.7.11.10.474
2bikBI1Serine/threonine-protein kinase pim-12.7.11.10.474
2iw84SPCyclin-dependent kinase 22.7.11.220.474
2pwlACPFibroblast growth factor receptor 2/0.474
2x2kX2KProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.474
4bchT7ZCyclin-dependent kinase 92.7.11.220.474
4j99ACPFibroblast growth factor receptor 2/0.474
1pyePM1Cyclin-dependent kinase 22.7.11.220.473
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.473
2jedLG8Protein kinase C theta type2.7.11.130.473
2uzlC94Cyclin-dependent kinase 22.7.11.220.473
2x6dX6DAurora kinase A2.7.11.10.473
3r9dX6BCyclin-dependent kinase 22.7.11.220.473
4kb81QOCasein kinase I isoform delta2.7.11.10.473
4o0wADNAurora kinase A2.7.11.10.473
3iw4LW4Protein kinase C alpha type2.7.11.130.472
3mfrANPPeripheral plasma membrane protein CASK2.7.11.10.472
4f640S8Fibroblast growth factor receptor 1/0.472
4nks2M2Fibroblast growth factor receptor 1/0.472
4oa9ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.472
1lp4ANPCasein kinase II subunit alpha2.7.11.10.471
1py5PY1TGF-beta receptor type-12.7.11.300.471
1q3dSTUGlycogen synthase kinase-3 beta2.7.11.260.471
1yhsSTUSerine/threonine-protein kinase pim-12.7.11.10.471
2dwbANPAurora kinase A2.7.11.10.471
2vuw5IDSerine/threonine-protein kinase haspin2.7.11.10.471
2xngA0HAurora kinase A2.7.11.10.471
3emg685Tyrosine-protein kinase SYK2.7.10.20.471
3vs0VS0Tyrosine-protein kinase HCK2.7.10.20.471
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.471
4dymIYZActivin receptor type-12.7.11.300.471
4jr3KJREpidermal growth factor receptor2.7.10.10.471
4yuqKS1Calmodulin-like domain protein kinase/0.471
1vjy460TGF-beta receptor type-12.7.11.300.470
1xr1ANPSerine/threonine-protein kinase pim-12.7.11.10.470
2c0oL2GTyrosine-protein kinase HCK2.7.10.20.470
3at4CCKCasein kinase II subunit alpha2.7.11.10.470
3du8553Glycogen synthase kinase-3 beta2.7.11.260.470
3lfqA28Cyclin-dependent kinase 22.7.11.220.470
4bieIE6Mitogen-activated protein kinase kinase kinase 52.7.11.250.470
4jajXU1Aurora kinase A2.7.11.10.470
5cnoANPEpidermal growth factor receptor2.7.10.10.470
2c6tDT5Cyclin-dependent kinase 22.7.11.220.469
2cdz23DSerine/threonine-protein kinase PAK 42.7.11.10.469
2xj1XJ1Serine/threonine-protein kinase pim-12.7.11.10.469
4enxZ20Serine/threonine-protein kinase pim-12.7.11.10.469
1gij2PUCyclin-dependent kinase 22.7.11.220.468
1y91CT9Cyclin-dependent kinase 22.7.11.220.468
2chlDKICasein kinase I isoform gamma-32.7.11.10.468
3a60STURibosomal protein S6 kinase beta-12.7.11.10.468
3blrCPBCyclin-dependent kinase 92.7.11.220.468
3cy2MB9Serine/threonine-protein kinase pim-12.7.11.10.468
3uimANPBRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 12.7.10.10.468
3vrzVRZTyrosine-protein kinase HCK2.7.10.20.468
3vs4VSFTyrosine-protein kinase HCK2.7.10.20.468
4bcmT7ZCyclin-dependent kinase 22.7.11.220.468
4dn5AGSMitogen-activated protein kinase kinase kinase 142.7.11.250.468
4jlcSU6Serine/threonine-protein kinase TBK12.7.11.10.468
4k0y1OASerine/threonine-protein kinase pim-12.7.11.10.468
2bdf24AProto-oncogene tyrosine-protein kinase Src2.7.10.20.467
2bkzSBCCyclin-dependent kinase 22.7.11.220.467
3fz1B98Cyclin-dependent kinase 22.7.11.220.467
3js2VM1Fibroblast growth factor receptor 1/0.467
4idtT28Mitogen-activated protein kinase kinase kinase 142.7.11.250.467
4iwq1FVSerine/threonine-protein kinase TBK12.7.11.10.467
4oacADPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.467
1dayGNPCasein kinase II subunit alpha2.7.11.10.466
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.466
1rw8580TGF-beta receptor type-12.7.11.300.466
2ejvNADL-threonine 3-dehydrogenase/0.466
2i0ePDSProtein kinase C beta type2.7.11.130.466
2itzIREEpidermal growth factor receptor2.7.10.10.466
3cy3JN5Serine/threonine-protein kinase pim-12.7.11.10.466
3gubGUBDeath-associated protein kinase 12.7.11.10.466
4idv13VMitogen-activated protein kinase kinase kinase 142.7.11.250.466
2f2cAP9Cyclin-dependent kinase 62.7.11.220.465
2uzeC95Cyclin-dependent kinase 22.7.11.220.465
3umxQ18Serine/threonine-protein kinase pim-12.7.11.10.465
4b7tCWTGlycogen synthase kinase-3 beta2.7.11.260.465
4bgePYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.465
4hbm0Y7E3 ubiquitin-protein ligase Mdm26.3.20.465
4kbk1QGCasein kinase I isoform delta2.7.11.10.465
4y93746Tyrosine-protein kinase/0.465
1finATPCyclin-dependent kinase 22.7.11.220.464
2brgDFYSerine/threonine-protein kinase Chk12.7.11.10.464
2v7a627Tyrosine-protein kinase ABL12.7.10.20.464
2x8iX8ISerine/threonine-protein kinase Chk12.7.11.10.464
3i60E86Mitogen-activated protein kinase 12.7.11.240.464
3r9hZ67Cyclin-dependent kinase 22.7.11.220.464
4b99R4LMitogen-activated protein kinase 72.7.11.240.464
4eutBX7Serine/threonine-protein kinase TBK12.7.11.10.464
5dt3ATPAurora kinase A2.7.11.10.464
2uzbC75Cyclin-dependent kinase 22.7.11.220.463
2uzuL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.463
3cxw7CPSerine/threonine-protein kinase pim-12.7.11.10.463
3s1h56ZCyclin-dependent kinase 22.7.11.220.463
4bcoT6QCyclin-dependent kinase 22.7.11.220.463
4fkw62KCyclin-dependent kinase 22.7.11.220.463
4fv1EK4Mitogen-activated protein kinase 12.7.11.240.463
4gk3L87Ephrin type-A receptor 32.7.10.10.463
4jr7GNPCasein kinase II subunit alpha2.7.11.10.463
5amnDTQProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.463
5d12G97Proto-oncogene tyrosine-protein kinase Src2.7.10.20.463
1uv5BRWGlycogen synthase kinase-3 beta2.7.11.260.462
2izrBRKCasein kinase I isoform gamma-32.7.11.10.462
3ggfGVDSerine/threonine-protein kinase 26/0.462
3hmm855TGF-beta receptor type-12.7.11.300.462
3mfuANPPeripheral plasma membrane protein CASK2.7.11.10.462
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.462
4fob0USALK tyrosine kinase receptor2.7.10.10.462
4gvjADPNon-receptor tyrosine-protein kinase TYK22.7.10.20.462
1gih1PUCyclin-dependent kinase 22.7.11.220.461
1oecAA2Fibroblast growth factor receptor 2/0.461
2bheBRYCyclin-dependent kinase 22.7.11.220.461
2j2iLY4Serine/threonine-protein kinase pim-12.7.11.10.461
2py3ACPFibroblast growth factor receptor 2/0.461
3bbtFMMReceptor tyrosine-protein kinase erbB-42.7.10.10.461
3bhh5CPCalcium/calmodulin-dependent protein kinase type II subunit beta2.7.11.170.461
3nr4PYVAbscisic acid receptor PYL2/0.461
3w2rW2REpidermal growth factor receptor2.7.10.10.461
4ftn2HKSerine/threonine-protein kinase Chk12.7.11.10.461
4gj30XPNon-receptor tyrosine-protein kinase TYK22.7.10.20.461
4qmlANPSerine/threonine-protein kinase 242.7.11.10.461
4wkqIREEpidermal growth factor receptor2.7.10.10.461
5a4kFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.461
1o6yACPSerine/threonine-protein kinase PknB2.7.11.10.460
1oguST8Cyclin-dependent kinase 22.7.11.220.460
1q97ATPSerine/threonine-protein kinase SKY12.7.11.10.460
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.460
2ow3BIMGlycogen synthase kinase-3 beta2.7.11.260.460
2wmuZYUSerine/threonine-protein kinase Chk12.7.11.10.460
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.460
3sc13S13-phosphoinositide-dependent protein kinase 12.7.11.10.460
3vryB43Tyrosine-protein kinase HCK2.7.10.20.460
4aqc88ATyrosine-protein kinase JAK2/0.460
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.460
2vttLZDCyclin-dependent kinase 22.7.11.220.459
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.459
4cfnJYMCyclin-dependent kinase 22.7.11.220.459
4f081RSTyrosine-protein kinase JAK2/0.459
4hge15VTyrosine-protein kinase JAK2/0.459
4n702HXSerine/threonine-protein kinase pim-12.7.11.10.459
1om1IQACasein kinase II subunit alpha2.7.11.10.458
2izsBRQCasein kinase I isoform gamma-32.7.11.10.458
2vv9IM9Cyclin-dependent kinase 22.7.11.220.458
3gu6ADPDeath-associated protein kinase 12.7.11.10.458
3hx4ANPCalmodulin-domain protein kinase 1/0.458
3jy0LYGSerine/threonine-protein kinase pim-12.7.11.10.458
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.458
4ezk0SDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.458
4fyn0VETyrosine-protein kinase SYK2.7.10.20.458
4hyi1AOSerine/threonine-protein kinase Chk12.7.11.10.458
4o0rX4ZSerine/threonine-protein kinase PAK 12.7.11.10.458
1ouk084Mitogen-activated protein kinase 14/0.457
2c6eHPMAurora kinase A2.7.11.10.457
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.457
2uzvSS5cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.457
3mvl38PMitogen-activated protein kinase 14/0.457
3nux3NVCyclin-dependent kinase 62.7.11.220.457
4hgl0YOCasein kinase I isoform gamma-32.7.11.10.457
4rrvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.457
1bwsNDPGDP-L-fucose synthase/0.456
1j1bANPGlycogen synthase kinase-3 beta2.7.11.260.456
1ydtIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.456
2fumMIXSerine/threonine-protein kinase PknB2.7.11.10.456
2ijmADPFocal adhesion kinase 12.7.10.20.456
3ml8ML8Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.456
4anwO92Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.456
4bzo676Serine/threonine-protein kinase pim-12.7.11.10.456
4l521ULMitogen-activated protein kinase kinase kinase 72.7.11.250.456
4rqkATP3-phosphoinositide-dependent protein kinase 12.7.11.10.456
1yi3LY2Serine/threonine-protein kinase pim-12.7.11.10.455
2c0tL3GTyrosine-protein kinase HCK2.7.10.20.455
2oh02PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.455
3bhtMFRCyclin-dependent kinase 22.7.11.220.455
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.455
3lpbNVBTyrosine-protein kinase JAK2/0.455
3ttiKBIMitogen-activated protein kinase 102.7.11.240.455
3vs3VSETyrosine-protein kinase HCK2.7.10.20.455
5auwQUEDeath-associated protein kinase 12.7.11.10.455
1pxoCK7Cyclin-dependent kinase 22.7.11.220.454
1wvxBD4Death-associated protein kinase 12.7.11.10.454
2bhhRYUCyclin-dependent kinase 22.7.11.220.454
3b8r887Vascular endothelial growth factor receptor 22.7.10.10.454
3c4zADPRhodopsin kinase/0.454
3ofm4B0Casein kinase II subunit alpha'2.7.11.10.454
3s2a2NQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.454
3vw6IM6Mitogen-activated protein kinase kinase kinase 52.7.11.250.454
4aojV4ZHigh affinity nerve growth factor receptor2.7.10.10.454
4c02TAKActivin receptor type-12.7.11.300.454
4fv6E57Mitogen-activated protein kinase 12.7.11.240.454
4g1wG1WMitogen-activated protein kinase 82.7.11.240.454
4hgs15GCasein kinase I isoform gamma-32.7.11.10.454
4iva1J5Tyrosine-protein kinase JAK2/0.454
4oh4ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.454
4wsqKSAAP2-associated protein kinase 12.7.11.10.454
4yryFADGlutamate synthase, beta subunit/0.454
1xwsBI1Serine/threonine-protein kinase pim-12.7.11.10.453
1ydrIQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.453
2wxvWXVCyclin-dependent kinase 22.7.11.220.453
2xyuQ9GEphrin type-A receptor 42.7.10.10.453
3adaNADSubunit alpha of sarocosine oxidase/0.453
3zrlZRLGlycogen synthase kinase-3 beta2.7.11.260.453
4anv751Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.453
4eon1ROCyclin-dependent kinase 22.7.11.220.453
4gh2HK0Serine/threonine-protein kinase Chk12.7.11.10.453
4jq8KJ8Epidermal growth factor receptor2.7.10.10.453
1jioDEB6-deoxyerythronolide B hydroxylase/0.452
1pyxANPGlycogen synthase kinase-3 beta2.7.11.260.452
1zp9ATPRIO-type serine/threonine-protein kinase Rio12.7.11.10.452
2c5nCK8Cyclin-dependent kinase 22.7.11.220.452
2etkHFSRho-associated protein kinase 12.7.11.10.452
2f7e2EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.452
2j0lANPFocal adhesion kinase 12.7.10.20.452
2uxoTACHTH-type transcriptional regulator TtgR/0.452
2vagV25Dual specificity protein kinase CLK12.7.12.10.452
2x8eX8ESerine/threonine-protein kinase Chk12.7.11.10.452
3ambVX6cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.452
3hrfATP3-phosphoinositide-dependent protein kinase 12.7.11.10.452
3tkuM77Serine/threonine-protein kinase MRCK beta2.7.11.10.452
4bznUGXSerine/threonine-protein kinase pim-12.7.11.10.452
4ct1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.452
4fl1ANPTyrosine-protein kinase SYK2.7.10.20.452
4q5jANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.452
5dr9SKEAurora kinase A2.7.11.10.452
1dm2HMDCyclin-dependent kinase 22.7.11.220.451
1ol7ADPAurora kinase A2.7.11.10.451
1sm2STUTyrosine-protein kinase ITK/TSK2.7.10.20.451
2ds11CDCyclin-dependent kinase 22.7.11.220.451
4anuEM7Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.451
4dk50KOPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.451
4hnf16WCasein kinase I isoform delta2.7.11.10.451
4k33ACPFibroblast growth factor receptor 32.7.10.10.451
1h1q2A6Cyclin-dependent kinase 22.7.11.220.450
1q99ANPSerine/threonine-protein kinase SKY12.7.11.10.450
1ykr628Cyclin-dependent kinase 22.7.11.220.450
1yw2PGJMitogen-activated protein kinase 14/0.450
2io6330Wee1-like protein kinase2.7.10.20.450
3bgqVX2Serine/threonine-protein kinase pim-12.7.11.10.450
3fzr3JZProtein-tyrosine kinase 2-beta2.7.10.20.450
3nunJMZ3-phosphoinositide-dependent protein kinase 12.7.11.10.450
3qaqQAQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.450
3qk0QK0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.450
3zrmZRMGlycogen synthase kinase-3 beta2.7.11.260.450
4loqSB4Mitogen-activated protein kinase 14/0.450
5cnnANPEpidermal growth factor receptor2.7.10.10.450
5cshATPCasein kinase II subunit alpha2.7.11.10.450
1hvlA76Gag-Pol polyprotein/0.449
1ke7LS3Cyclin-dependent kinase 22.7.11.220.449
1m2rMNYCasein kinase II subunit alpha2.7.11.10.449
2w9sTOPDihydrofolate reductase type 1 from Tn40031.5.1.30.449
3at3ATKCasein kinase II subunit alpha2.7.11.10.449
3lltANPProtein serine/threonine kinase-1/0.449
3prfFP3Serine/threonine-protein kinase B-raf2.7.11.10.449
3qcq3Q03-phosphoinositide-dependent protein kinase 12.7.11.10.449
4deeADPAurora kinase A2.7.11.10.449
4fg7ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.449
5dnrATPAurora kinase A2.7.11.10.449
5dpvSKEAurora kinase A2.7.11.10.449
2j0k4STFocal adhesion kinase 12.7.10.20.448
2qo7ANPEphrin type-A receptor 32.7.10.10.448
3a4oSTUTyrosine-protein kinase Lyn2.7.10.20.448
3gu83GUDeath-associated protein kinase 12.7.11.10.448
3hrcATP3-phosphoinositide-dependent protein kinase 12.7.11.10.448
3nszANPCasein kinase II subunit alpha2.7.11.10.448
3nwxKVSGag-Pol polyprotein3.4.23.160.448
3rk708ZCyclin-dependent kinase 22.7.11.220.448
3rvg17PTyrosine-protein kinase JAK2/0.448
3uzp0CKCasein kinase I isoform delta2.7.11.10.448
4dfn0K1Tyrosine-protein kinase SYK2.7.10.20.448
4fkv61KCyclin-dependent kinase 22.7.11.220.448
4g34924Eukaryotic translation initiation factor 2-alpha kinase 32.7.11.10.448
4lm5Q17Serine/threonine-protein kinase pim-12.7.11.10.448
4ogrADNCyclin-dependent kinase 92.7.11.220.448
2etm7PYFocal adhesion kinase 12.7.10.20.447
2hk51BMTyrosine-protein kinase HCK2.7.10.20.447
3ac5KZMTyrosine-protein kinase Lck2.7.10.20.447
3apfBMWPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
3bi6396Wee1-like protein kinase2.7.10.20.447
3d7tSTUTyrosine-protein kinase CSK/0.447
4enyJ19Serine/threonine-protein kinase pim-12.7.11.10.447
4eooATPCyclin-dependent kinase 22.7.11.220.447
4f650S9Fibroblast growth factor receptor 1/0.447
4ijp1EHSerine/threonine-protein kinase PRP4 homolog2.7.11.10.447
5dr6SKEAurora kinase A2.7.11.10.447
1ir3ANPInsulin receptor2.7.10.10.446
2b9iADPMitogen-activated protein kinase FUS32.7.11.240.446
2c475IDCasein kinase I isoform gamma-2/0.446
2e9oA58Serine/threonine-protein kinase Chk12.7.11.10.446
2etrY27Rho-associated protein kinase 12.7.11.10.446
2o65MYFSerine/threonine-protein kinase pim-12.7.11.10.446
2pmoHMDProtein kinase 7/0.446
2uw0GVKcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.446
2xvdAS6Ephrin type-B receptor 42.7.10.10.446
3amaSKEcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.446
3bgpVX1Serine/threonine-protein kinase pim-12.7.11.10.446
3i81EBIInsulin-like growth factor 1 receptor2.7.10.10.446
3kf7L9GMitogen-activated protein kinase 14/0.446
3oroAGSSerine/threonine protein kinase/0.446
3vbq0F5Serine/threonine-protein kinase pim-12.7.11.10.446
3zrkZRKGlycogen synthase kinase-3 beta2.7.11.260.446
4a06ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.446
4b7sQLECytochrome P450 monooxygenase PikC/0.446
4bfmANPMaternal embryonic leucine zipper kinase2.7.11.10.446
4dgmAGICasein kinase II subunit alpha2.7.11.10.446
4g160VMCasein kinase I isoform gamma-32.7.11.10.446
4hle17VPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
4nm0ADPGlycogen synthase kinase-3 beta2.7.11.260.446
1dz6CAMCamphor 5-monooxygenase1.14.15.10.445
1r0eDFNGlycogen synthase kinase-3 beta2.7.11.260.445
2e9p77ASerine/threonine-protein kinase Chk12.7.11.10.445
2gdo12CSerine/threonine-protein kinase Chk12.7.11.10.445
2jkoBIJFocal adhesion kinase 12.7.10.20.445
2r3jSCJCyclin-dependent kinase 22.7.11.220.445
2uxpCLMHTH-type transcriptional regulator TtgR/0.445
2vf0F89Thymidylate synthase/0.445
3bheBZNGag-Pol polyprotein3.4.23.160.445
3hl7I47Mitogen-activated protein kinase 14/0.445
3ma301ISerine/threonine-protein kinase pim-12.7.11.10.445
4en4ATPPyridoxal kinase2.7.1.350.445
4ivb1J5Tyrosine-protein kinase JAK1/0.445
4ykfFADAlkyl hydroperoxide reductase subunit F1.8.10.445
5av2KMPDeath-associated protein kinase 12.7.11.10.445
1m17AQ4Epidermal growth factor receptor2.7.10.10.444
1rfuADPPyridoxal kinase2.7.1.350.444
2i4zDRHPeroxisome proliferator-activated receptor gamma/0.444
2itpAEEEpidermal growth factor receptor2.7.10.10.444
2jdsL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.444
2xm9LWHSerine/threonine-protein kinase Chk22.7.11.10.444
3cr0809Wee1-like protein kinase2.7.10.20.444
3l9lL9LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.444
3q4zANPSerine/threonine-protein kinase PAK 12.7.11.10.444
3qtrX36Cyclin-dependent kinase 22.7.11.220.444
3r83Z14Cyclin-dependent kinase 22.7.11.220.444
3wmxNADNAD dependent epimerase/dehydratase/0.444
4awiAQ2Mitogen-activated protein kinase 82.7.11.240.444
4flh14KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
4krcAGSCyclin-dependent protein kinase PHO852.7.11.220.444
4mxxDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.444
1ivp1ZKGag-Pol polyprotein/0.443
1oiqHDUCyclin-dependent kinase 22.7.11.220.443
1xddAAYIntegrin alpha-L/0.443
2cgu3A3Serine/threonine-protein kinase Chk12.7.11.10.443
2e9v85ASerine/threonine-protein kinase Chk12.7.11.10.443
2i4pDRHPeroxisome proliferator-activated receptor gamma/0.443
3biz61EWee1-like protein kinase2.7.10.20.443
3dogNNNCyclin-dependent kinase 22.7.11.220.443
3vs6VSHTyrosine-protein kinase HCK2.7.10.20.443
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.443
4btjATPTau-tubulin kinase 12.7.11.10.443
4cztCPSCBL-interacting serine/threonine-protein kinase 232.7.11.10.443
4ezj0SCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
4f9c0SXCell division cycle 7-related protein kinase2.7.11.10.443
4g3e0WCMitogen-activated protein kinase kinase kinase 142.7.11.250.443
4i0s1B5Tyrosine-protein kinase SYK2.7.10.20.443
4otiMI1Serine/threonine-protein kinase N1/0.443
2vtpLZ9Cyclin-dependent kinase 22.7.11.220.442
3el51UNGag-Pol polyprotein/0.442
3fwfCAMCamphor 5-monooxygenase1.14.15.10.442
3qd03Q43-phosphoinositide-dependent protein kinase 12.7.11.10.442
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.442
3tz3B36Acetyl-CoA carboxylase/0.442
3u9eCOALmo1369 protein/0.442
3v5j0F2Tyrosine-protein kinase ITK/TSK2.7.10.20.442
3vf80JETyrosine-protein kinase SYK2.7.10.20.442
4feq0T8Tyrosine-protein kinase receptor TYRO32.7.10.10.442
4hvb19PPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
4hyh1AMSerine/threonine-protein kinase Chk12.7.11.10.442
5dosATPAurora kinase A2.7.11.10.442
1difA85Gag-Pol polyprotein/0.441
1xl2189Gag-Pol polyprotein3.4.23.160.441
1y0s331Peroxisome proliferator-activated receptor delta/0.441
2a0cCK9Cyclin-dependent kinase 22.7.11.220.441
2hrcCHDFerrochelatase, mitochondrial4.99.1.10.441
2hxq373Serine/threonine-protein kinase Chk12.7.11.10.441
2y4gTIRTamL/0.441
3f883HTGlycogen synthase kinase-3 beta2.7.11.260.441
3m42HGFMAP kinase-activated protein kinase 22.7.11.10.441
3qtzX42Cyclin-dependent kinase 22.7.11.220.441
4aotGW8Serine/threonine-protein kinase 102.7.11.10.441
4aw1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.441
4g3jVNTLanosterol 14-alpha-demethylase/0.441
4g7gVFVLanosterol 14-alpha-demethylase/0.441
4jq7KJQEpidermal growth factor receptor2.7.10.10.441
4mq22C4Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.441
5dt4ATPAurora kinase A2.7.11.10.441
1d4aFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.440
1qnfFADDeoxyribodipyrimidine photo-lyase4.1.99.30.440
2b7aIZATyrosine-protein kinase JAK2/0.440
2hw2RFPRifampin ADP-ribosyl transferase/0.440
2wmqZYQSerine/threonine-protein kinase Chk12.7.11.10.440
3lj3WYEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.440
3pjcPJCTyrosine-protein kinase JAK32.7.10.20.440
3r71X86Cyclin-dependent kinase 22.7.11.220.440
3zm422TDual specificity mitogen-activated protein kinase kinase 12.7.12.20.440
4e93GUITyrosine-protein kinase Fes/Fps2.7.10.20.440
4fg8ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.440
4gu94GUFocal adhesion kinase 12.7.10.20.440
4im01FVSerine/threonine-protein kinase TBK12.7.11.10.440
4j711JXGlycogen synthase kinase-3 beta2.7.11.260.440
4nfn2KCTau-tubulin kinase 12.7.11.10.440
4othDRNSerine/threonine-protein kinase N1/0.440