sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1mzn | BM6 | Retinoic acid receptor RXR-alpha |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1mzn | BM6 | Retinoic acid receptor RXR-alpha | / | 1.000 | |
| 1mvc | BM6 | Retinoic acid receptor RXR-alpha | / | 0.643 | |
| 4k6i | 9RA | Retinoic acid receptor RXR-alpha | / | 0.639 | |
| 1rdt | L79 | Retinoic acid receptor RXR-alpha | / | 0.633 | |
| 1fm6 | 9CR | Retinoic acid receptor RXR-alpha | / | 0.623 | |
| 2p1v | 5TN | Retinoic acid receptor RXR-alpha | / | 0.616 | |
| 2p1t | 3TN | Retinoic acid receptor RXR-alpha | / | 0.614 | |
| 3h0a | 9RA | Retinoic acid receptor RXR-alpha | / | 0.609 | |
| 1xiu | REA | Retinoic acid receptor RXR | / | 0.603 | |
| 1k74 | 9CR | Retinoic acid receptor RXR-alpha | / | 0.602 | |
| 3oap | REA | Retinoic acid receptor RXR-alpha | / | 0.596 | |
| 1xls | REA | Retinoic acid receptor RXR-alpha | / | 0.594 | |
| 2p1u | 4TN | Retinoic acid receptor RXR-alpha | / | 0.591 | |
| 4m8e | 29V | Retinoic acid receptor RXR-alpha | / | 0.590 | |
| 1fby | REA | Retinoic acid receptor RXR-alpha | / | 0.588 | |
| 4m8h | R4M | Retinoic acid receptor RXR-alpha | / | 0.578 | |
| 3uvv | REA | Retinoic acid receptor RXR-alpha | / | 0.572 | |
| 3fc6 | REA | Retinoic acid receptor RXR-alpha | / | 0.571 | |
| 3fal | REA | Retinoic acid receptor RXR-alpha | / | 0.570 | |
| 2acl | REA | Retinoic acid receptor RXR-alpha | / | 0.567 | |
| 1uhl | MEI | Retinoic acid receptor RXR-beta | / | 0.566 | |
| 4k4j | 1O8 | Retinoic acid receptor RXR-alpha | / | 0.566 | |
| 1fm9 | 9CR | Retinoic acid receptor RXR-alpha | / | 0.564 | |
| 3up0 | D7S | aceDAF-12 | / | 0.499 | |
| 4jlj | 1NM | Deoxycytidine kinase | 2.7.1.74 | 0.497 | |
| 3gbk | 2PQ | Peroxisome proliferator-activated receptor gamma | / | 0.494 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.493 | |
| 4lxj | LAN | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.493 | |
| 3q0g | BCO | Probable enoyl-CoA hydratase echA8 | 4.2.1.17 | 0.489 | |
| 3p9t | TCL | Repressor | / | 0.488 | |
| 2jc6 | QPP | Calcium/calmodulin-dependent protein kinase type 1D | 2.7.11.17 | 0.487 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.485 | |
| 4xuh | SFI | Peroxisome proliferator-activated receptor gamma | / | 0.485 | |
| 2ydo | ADN | Adenosine receptor A2a | / | 0.484 | |
| 3iro | 2CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.482 | |
| 4nb6 | 444 | Nuclear receptor ROR-gamma | / | 0.482 | |
| 5hs1 | VOR | Lanosterol 14-alpha demethylase | / | 0.482 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.481 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.480 | |
| 3gyt | DL4 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.480 | |
| 3p99 | LNP | Lanosterol 14-alpha-demethylase | / | 0.480 | |
| 4q72 | FAD | Bifunctional protein PutA | / | 0.480 | |
| 2p15 | EZT | Estrogen receptor | / | 0.479 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.479 | |
| 3gyu | DL7 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.479 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.478 | |
| 3qm4 | PN0 | Cytochrome P450 2D6 | / | 0.478 | |
| 1e7a | PFL | Serum albumin | / | 0.476 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.475 | |
| 1osv | CHC | Bile acid receptor | / | 0.475 | |
| 1q0r | AKT | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.475 | |
| 1s3y | TQT | Dihydrofolate reductase | 1.5.1.3 | 0.473 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.473 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.473 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.473 | |
| 2b03 | TUD | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.472 | |
| 3wiy | LC6 | Induced myeloid leukemia cell differentiation protein Mcl-1 | / | 0.472 | |
| 4y8v | ADP | Acyl-CoA synthetase (NDP forming) | / | 0.472 | |
| 1rf9 | DBR | Camphor 5-monooxygenase | 1.14.15.1 | 0.471 | |
| 3c0g | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.471 | |
| 4jvb | 1M0 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.471 | |
| 5bp9 | SAH | Putative methyltransferase protein | / | 0.471 | |
| 1phg | MYT | Camphor 5-monooxygenase | 1.14.15.1 | 0.470 | |
| 1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.470 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.470 | |
| 1g3m | PCQ | Estrogen sulfotransferase | 2.8.2.4 | 0.469 | |
| 1pkf | EPD | Epothilone C/D epoxidase | 1.14 | 0.469 | |
| 3lfe | Z84 | Mitogen-activated protein kinase 14 | / | 0.469 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.469 | |
| 2iod | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.468 | |
| 3i1f | GCP | Translation initiation factor 2 subunit gamma | / | 0.468 | |
| 3clb | TMQ | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.467 | |
| 3gcn | TYR_GLN_PHE | Serine endoprotease DegS | 3.4.21.107 | 0.467 | |
| 3kpz | ZNE | Vitamin D3 receptor | / | 0.467 | |
| 3zia | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.467 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
| 4nie | NBH | Nuclear receptor ROR-gamma | / | 0.467 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.467 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.466 | |
| 3up3 | XCA | aceDAF-12 | / | 0.466 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.466 | |
| 1kzj | CB3 | Thymidylate synthase | / | 0.465 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.465 | |
| 1ot7 | IU5 | Bile acid receptor | / | 0.465 | |
| 2wpw | ACO | Orf14 | / | 0.465 | |
| 2xc3 | RT8 | Steroid C26-monooxygenase | 1.14.13.141 | 0.465 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.465 | |
| 3sn7 | 540 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.465 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.465 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.464 | |
| 1p44 | GEQ | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.464 | |
| 1rd4 | L08 | Integrin alpha-L | / | 0.464 | |
| 3t8x | T8X | T-cell surface glycoprotein CD1b | / | 0.464 | |
| 1fx9 | MJI | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.463 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.463 | |
| 1kk4 | ACO | Streptogramin A acetyltransferase | 2.3.1 | 0.463 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.463 | |
| 2b36 | 5PP | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.463 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.463 | |
| 2wpx | ACO | Orf14 | / | 0.463 | |
| 2y98 | MIV | Mycinamicin IV hydroxylase/epoxidase | / | 0.463 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.463 | |
| 3gds | VAL_TYR_TYR_PHE | Serine endoprotease DegS | 3.4.21.107 | 0.463 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.463 | |
| 4iui | 1GQ | Estrogen receptor | / | 0.463 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.462 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.462 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.462 | |
| 2ewp | TXF | Estrogen-related receptor gamma | / | 0.462 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.462 | |
| 3njo | PYV | Abscisic acid receptor PYR1 | / | 0.462 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.462 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.462 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.461 | |
| 1fml | RTL | Retinol dehydratase | / | 0.461 | |
| 1iep | STI | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.461 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.461 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.461 | |
| 2azy | CHD | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.461 | |
| 2zla | VDB | Vitamin D3 receptor | / | 0.461 | |
| 3byz | H11 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.461 | |
| 3irn | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.461 | |
| 3p2e | SAH | 16S rRNA (adenine(1408)-N(1))-methyltransferase | 2.1.1.180 | 0.461 | |
| 4a2j | AS0 | Progesterone receptor | / | 0.461 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.461 | |
| 4jlk | 1NO | Deoxycytidine kinase | 2.7.1.74 | 0.461 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.461 | |
| 1zdw | FLV | Prenyltransferase | / | 0.460 | |
| 2pir | DHT | Androgen receptor | / | 0.460 | |
| 3hcr | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.460 | |
| 3ipt | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.460 | |
| 3qly | 55V | Uncharacterized protein | / | 0.460 | |
| 4dvq | 1CA | Cytochrome P450 11B2, mitochondrial | 1.14.15.4 | 0.460 | |
| 1hk2 | T44 | Serum albumin | / | 0.459 | |
| 2c3q | GTX | Glutathione S-transferase theta-1 | 2.5.1.18 | 0.459 | |
| 2ejz | SAH | Diphthine synthase | / | 0.459 | |
| 2vn0 | TDZ | Cytochrome P450 2C8 | / | 0.459 | |
| 2znn | S44 | Peroxisome proliferator-activated receptor alpha | / | 0.459 | |
| 3ute | FAD | UDP-galactopyranose mutase | / | 0.459 | |
| 3w5q | 3KL | Vitamin D3 receptor | / | 0.459 | |
| 4bmp | FMN | Protein NrdI | / | 0.459 | |
| 4o70 | 1QK | Bromodomain-containing protein 4 | / | 0.459 | |
| 5bn3 | ADP | V-type ATP synthase alpha chain | / | 0.459 | |
| 5bn3 | ADP | NEQ263 | / | 0.459 | |
| 1q5d | EPB | Epothilone C/D epoxidase | 1.14 | 0.458 | |
| 2aib | ERG | Beta-elicitin cinnamomin | / | 0.458 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 3is9 | AC7 | Gag-Pol polyprotein | 2.7.7.49 | 0.458 | |
| 3vrv | YSD | Vitamin D3 receptor | / | 0.458 | |
| 3vtb | TKA | Vitamin D3 receptor | / | 0.458 | |
| 4h97 | 53S | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 4jbt | ASD | Cytochrome P450 monooxygenase | / | 0.458 | |
| 1fdu | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.457 | |
| 2bel | CBO | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.457 | |
| 2gpv | OHT | Estrogen-related receptor gamma | / | 0.457 | |
| 2z3u | CRR | Cytochrome P450 | / | 0.457 | |
| 3lu6 | IMX | Serum albumin | / | 0.457 | |
| 3sp9 | IL2 | Peroxisome proliferator-activated receptor delta | / | 0.457 | |
| 4jvn | YUG | Estrogen sulfotransferase | 2.8.2.4 | 0.457 | |
| 1dna | CB3 | Thymidylate synthase | / | 0.456 | |
| 1noo | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.456 | |
| 2tsc | CB3 | Thymidylate synthase | / | 0.456 | |
| 2vnh | FAD | NADPH:ferredoxin reductase | / | 0.456 | |
| 3d75 | NBB | Pheromone-binding protein ASP1 | / | 0.456 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.456 | |
| 3lfc | Z86 | Mitogen-activated protein kinase 14 | / | 0.456 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.456 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.456 | |
| 4jx1 | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.456 | |
| 4okb | 198 | Androgen receptor | / | 0.456 | |
| 4z63 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.456 | |
| 1cjk | FOK | Adenylate cyclase type 2 | / | 0.455 | |
| 1cjk | FOK | Adenylate cyclase type 5 | / | 0.455 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.455 | |
| 1tvr | TB9 | Gag-Pol polyprotein | 2.7.7.49 | 0.455 | |
| 2chw | 039 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.455 | |
| 2ph5 | NAD | Homospermidine synthase | / | 0.455 | |
| 2pnj | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.455 | |
| 3ad9 | NAD | Subunit alpha of sarocosine oxidase | / | 0.455 | |
| 3cx5 | SMA | Cytochrome b | / | 0.455 | |
| 3vf6 | 0H6 | Glucokinase | 2.7.1.2 | 0.455 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.455 | |
| 4fjz | 4FJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.455 | |
| 4jnc | 1LF | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.455 | |
| 4lxh | C1E | Alpha/beta hydrolase fold | / | 0.455 | |
| 5iub | CLR | Adenosine receptor A2a | / | 0.455 | |
| 4z34 | ON7 | Lysophosphatidic acid receptor 1 | / | 0.455 | |
| 1nce | CB3 | Thymidylate synthase | / | 0.454 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 2pnu | ENM | Androgen receptor | / | 0.454 | |
| 3a3y | OBN | Sodium/potassium-transporting ATPase subunit alpha | / | 0.454 | |
| 3bxx | QUE | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.454 | |
| 4jvl | EST | Estrogen sulfotransferase | 2.8.2.4 | 0.454 | |
| 4n4t | 2GV | Tankyrase-1 | 2.4.2.30 | 0.454 | |
| 2hk9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.453 | |
| 2hw2 | RFP | Rifampin ADP-ribosyl transferase | / | 0.453 | |
| 2rh9 | IGP | Tryptophan synthase alpha chain | / | 0.453 | |
| 2uxh | QUE | HTH-type transcriptional regulator TtgR | / | 0.453 | |
| 2uxp | CLM | HTH-type transcriptional regulator TtgR | / | 0.453 | |
| 3imx | B84 | Glucokinase | 2.7.1.2 | 0.453 | |
| 3p6n | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.453 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.453 | |
| 4a84 | DXC | Major pollen allergen Bet v 1-A | / | 0.453 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 4dvi | 2IW | Tankyrase-1 | 2.4.2.30 | 0.453 | |
| 4ead | 0NP | Thymidine phosphorylase | 2.4.2.4 | 0.453 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.453 | |
| 4lsj | LSJ | Glucocorticoid receptor | / | 0.453 | |
| 4uym | VOR | 14-alpha sterol demethylase Cyp51B | / | 0.453 | |
| 5jtb | ZMA | Adenosine receptor A2a | / | 0.453 | |
| 2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.452 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.452 | |
| 3cib | 314 | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 3p6p | A6B | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 3pb3 | SAH | 16S rRNA (adenine(1408)-N(1))-methyltransferase | 2.1.1.180 | 0.452 | |
| 3tda | PN0 | Cytochrome P450 2D6 | / | 0.452 | |
| 3w0j | T08 | Vitamin D3 receptor | / | 0.452 | |
| 4g1n | NZT | Pyruvate kinase PKM | 2.7.1.40 | 0.452 | |
| 4hle | 17V | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.452 | |
| 4iah | 1DX | Alr2278 protein | / | 0.452 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.452 | |
| 5cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 3uzc | T4E | Adenosine receptor A2a | / | 0.452 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 3cic | 316 | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 3dxj | NE6 | DNA-directed RNA polymerase subunit beta | / | 0.451 | |
| 3dxj | NE6 | DNA-directed RNA polymerase subunit beta' | / | 0.451 | |
| 3irm | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.451 | |
| 3rpn | GTX | Glutathione S-transferase kappa 1 | 2.5.1.18 | 0.451 | |
| 3t3r | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.451 | |
| 3tub | FPU | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.451 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.451 | |
| 4hw3 | 19G | Induced myeloid leukemia cell differentiation protein Mcl-1 | / | 0.451 | |
| 4jx1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 4l9q | 9TP | Serum albumin | / | 0.451 | |
| 4p6w | MOF | Glucocorticoid receptor | / | 0.451 | |
| 4zm6 | ACO | N-acetyl-beta-D glucosaminidase | / | 0.451 | |
| 6cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 1crb | RTL | Retinol-binding protein 1 | / | 0.450 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1ot7 | CHC | Bile acid receptor | / | 0.450 | |
| 1p7t | ACO | Malate synthase G | / | 0.450 | |
| 1xs7 | MMI | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 1ykd | CMP | Adenylate cyclase | / | 0.450 | |
| 2fzh | DH1 | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 2p7z | OHT | Estrogen-related receptor gamma | / | 0.450 | |
| 2w4q | CBW | Prostaglandin reductase 2 | 1.3.1.48 | 0.450 | |
| 3ruk | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.450 | |
| 4ixd | 1HV | Integrin alpha-L | / | 0.450 | |
| 4rlh | 0WE | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.450 | |
| 4twn | B96 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.450 | |
| 4wo5 | 324 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.450 | |
| 1bvr | THT | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.449 | |
| 1e1n | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.449 | |
| 1jtu | LYB | Thymidylate synthase | / | 0.449 | |
| 1ly4 | COQ | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.449 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 3sgv | 2BJ | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.449 | |
| 4bkj | STI | Epithelial discoidin domain-containing receptor 1 | 2.7.10.1 | 0.449 | |
| 4g1y | 0VO | Vitamin D3 receptor A | / | 0.449 | |
| 4jib | 1L6 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.449 | |
| 4tzt | 468 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.449 | |
| 5k2d | ZMA | Adenosine receptor A2a | / | 0.449 | |
| 1adf | TAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.448 | |
| 1daj | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1eio | GCH | Gastrotropin | / | 0.448 | |
| 1lhw | ESM | Sex hormone-binding globulin | / | 0.448 | |
| 1n83 | CLR | Nuclear receptor ROR-alpha | / | 0.448 | |
| 1olm | VTQ | SEC14-like protein 2 | / | 0.448 | |
| 1xdk | REA | Retinoic acid receptor beta | / | 0.448 | |
| 3cyl | VIT | Basic phospholipase A2 homolog piratoxin-2 | / | 0.448 | |
| 3l6j | Z90 | Alr2278 protein | / | 0.448 | |
| 3lu8 | IQX | Serum albumin | / | 0.448 | |
| 3th8 | TH9 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.448 | |
| 4boe | CLR | Japanin | / | 0.448 | |
| 4d0l | 093 | Phosphatidylinositol 4-kinase beta | 2.7.1.67 | 0.448 | |
| 4l8u | 9AZ | Serum albumin | / | 0.448 | |
| 5kf8 | ACO | Predicted acetyltransferase | / | 0.448 | |
| 3rfm | CFF | Adenosine receptor A2a | / | 0.448 | |
| 2r3x | GTX | Glutathione S-transferase A1 | 2.5.1.18 | 0.447 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.447 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.447 | |
| 3g70 | A5T | Renin | 3.4.23.15 | 0.447 | |
| 3ipu | O40 | Oxysterols receptor LXR-alpha | / | 0.447 | |
| 3r5z | F42 | Uncharacterized protein | / | 0.447 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.447 | |
| 4apu | A2K | Progesterone receptor | / | 0.447 | |
| 4at0 | FAD | Possible succinate dehydrogenase | / | 0.447 | |
| 4ia2 | BIV | Vitamin D3 receptor A | / | 0.447 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.447 | |
| 4nm9 | FAD | Bifunctional protein PutA | / | 0.447 | |
| 4okx | 198 | Androgen receptor | / | 0.447 | |
| 4u9z | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.447 | |
| 4zhi | ADP | Kinesin-like protein KIF11 | / | 0.447 | |
| 5kf2 | ACO | Predicted acetyltransferase | / | 0.447 | |
| 5kgh | ACO | Predicted acetyltransferase | / | 0.447 | |
| 1mj3 | HXC | Enoyl-CoA hydratase, mitochondrial | 4.2.1.17 | 0.446 | |
| 1qlh | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.446 | |
| 1sqv | UHD | Cytochrome b | / | 0.446 | |
| 1ysx | 4EB | Serum albumin | / | 0.446 | |
| 2bxq | IMN | Serum albumin | / | 0.446 | |
| 2c94 | TSF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.446 | |
| 2uxu | NAR | HTH-type transcriptional regulator TtgR | / | 0.446 | |
| 3b9l | AZZ | Serum albumin | / | 0.446 | |
| 3cge | NDP | Coenzyme A disulfide reductase | / | 0.446 | |
| 3d5q | T30 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.446 | |
| 3h1v | TK1 | Glucokinase | 2.7.1.2 | 0.446 | |
| 3new | 3NE | Mitogen-activated protein kinase 14 | / | 0.446 | |
| 3s41 | S41 | Glucokinase | 2.7.1.2 | 0.446 | |
| 4dch | 4DC | Glucokinase | 2.7.1.2 | 0.446 | |
| 4iaq | 2GM | 5-hydroxytryptamine receptor 1B | / | 0.446 | |
| 4j53 | 1J4 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.446 | |
| 4kqr | VPP | Peptidoglycan D,D-transpeptidase FtsI | / | 0.446 | |
| 4mt9 | 2D6 | Tankyrase-1 | 2.4.2.30 | 0.446 | |
| 5k2b | ZMA | Adenosine receptor A2a | / | 0.446 | |
| 3eml | ZMA | Adenosine receptor A2a | / | 0.446 | |
| 1n8w | COA | Malate synthase G | / | 0.445 | |
| 1zg3 | 2HI | Isoflavone 4'-O-methyltransferase | / | 0.445 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.445 | |
| 3w5p | 4OA | Vitamin D3 receptor | / | 0.445 | |
| 4bfr | J82 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform | 2.7.1.153 | 0.445 | |
| 4bii | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.445 | |
| 4nmb | FAD | Bifunctional protein PutA | / | 0.445 | |
| 1pz1 | NAP | General stress protein 69 | / | 0.444 | |
| 1re7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1sqb | AZO | Cytochrome b | / | 0.444 | |
| 1trg | CB3 | Thymidylate synthase | / | 0.444 | |
| 2ntv | P1H | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.444 | |
| 2ops | HBQ | Gag-Pol polyprotein | 2.7.7.49 | 0.444 | |
| 3ar4 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.444 | |
| 3c14 | FOK | Adenylate cyclase type 2 | / | 0.444 | |
| 3c14 | FOK | Adenylate cyclase type 5 | / | 0.444 | |
| 3lpi | Z74 | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 3v49 | PK0 | Androgen receptor | / | 0.444 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.444 | |
| 4k4f | K4F | Tankyrase-1 | 2.4.2.30 | 0.444 | |
| 5akk | 1P8 | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.444 | |
| 5hbr | COA | Acyl-CoA synthetase (NDP forming) | / | 0.444 | |
| 1kl2 | FON | Serine hydroxymethyltransferase | / | 0.443 | |
| 1re9 | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 1txt | CAA | HMG-CoA synthase | / | 0.443 | |
| 2e9a | B28 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.443 | |
| 2yiu | SMA | Cytochrome b | / | 0.443 | |
| 3c1t | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.443 | |
| 3dl9 | V2H | Vitamin D 25-hydroxylase | / | 0.443 | |
| 3inv | C50 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.443 | |
| 3jyn | NDP | Quinone oxidoreductase | / | 0.443 | |
| 3vjc | ZGA | Squalene synthase | 2.5.1.21 | 0.443 | |
| 4cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 4dhy | S41 | Glucokinase | 2.7.1.2 | 0.443 | |
| 4fhi | 0S4 | Vitamin D3 receptor A | / | 0.443 | |
| 4h3c | 0YZ | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.443 | |
| 4iae | 1DX | Alr2278 protein | / | 0.443 | |
| 4jji | NAD | Alcohol dehydrogenase class-3 | / | 0.443 | |
| 5bn4 | ANP | V-type ATP synthase alpha chain | / | 0.443 | |
| 5kf9 | ACO | Predicted acetyltransferase | / | 0.443 | |
| 1diu | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1drb | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1qzf | CB3 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.442 | |
| 2e98 | B29 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.442 | |
| 2ewa | SB2 | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 3aba | FLI | Cytochrome P450 | / | 0.442 | |
| 3bfa | 9OD | Odorant binding protein ASP1 | / | 0.442 | |
| 3bgx | MEF | Thymidylate synthase | / | 0.442 | |
| 3fco | IIG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.442 | |
| 3gmd | 2M3 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.442 | |
| 3h1j | SMA | Cytochrome b | / | 0.442 | |
| 3ocp | CMP | cGMP-dependent protein kinase 1 | 2.7.11.12 | 0.442 | |
| 3pn1 | IVH | DNA ligase | / | 0.442 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.442 | |
| 3s3v | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 3tk3 | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.442 | |
| 4bge | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 4dsc | A8S | Abscisic acid receptor PYL3 | / | 0.442 | |
| 4g1d | 0VK | Vitamin D3 receptor A | / | 0.442 | |
| 4kla | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.442 | |
| 4v12 | POG | MaoC like domain protein | / | 0.442 | |
| 1nzy | BCA | 4-chlorobenzoyl coenzyme A dehalogenase | 3.8.1.7 | 0.441 | |
| 1pp9 | SMA | Cytochrome b | / | 0.441 | |
| 1xu9 | CPS | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.441 | |
| 2blc | CP7 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.441 | |
| 2ivp | ATP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.441 | |
| 2o7p | NAP | Riboflavin biosynthesis protein RibD | / | 0.441 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.441 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.441 | |
| 2y46 | MIV | Mycinamicin IV hydroxylase/epoxidase | / | 0.441 | |
| 3aos | JH2 | Hemolymph juvenile hormone binding protein | / | 0.441 | |
| 3c0i | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.441 | |
| 3d3e | D3E | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.441 | |
| 3ol5 | SAW | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 3p6m | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 3p6o | ETG | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 3tgu | WF3 | Cytochrome b | / | 0.441 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.441 | |
| 4eqw | COA | Coenzyme A disulfide reductase | / | 0.441 | |
| 4lb2 | DM5 | Serum albumin | / | 0.441 | |
| 4r21 | STR | Cytochrome P450 family 17 polypeptide 2 | / | 0.441 | |
| 4x7w | MVI | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.441 | |
| 1ek2 | CDU | Bifunctional epoxide hydrolase 2 | / | 0.440 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1sui | FRE | Caffeoyl-CoA O-methyltransferase | 2.1.1.104 | 0.440 | |
| 2aaz | CB3 | Thymidylate synthase | 2.1.1.45 | 0.440 | |
| 2abj | CBC | Branched-chain-amino-acid aminotransferase, cytosolic | 2.6.1.42 | 0.440 | |
| 2agv | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.440 | |
| 2b37 | 8PS | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 2eix | FAD | NADH-cytochrome b5 reductase | / | 0.440 | |
| 2g2h | P16 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.440 | |
| 2hxz | H7J | Cathepsin S | 3.4.22.27 | 0.440 | |
| 2pr2 | DG1 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 2qd3 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.440 | |
| 2w3v | TOP | Dihydrofolate reductase | / | 0.440 | |
| 2xvv | 9DN | Serum albumin | / | 0.440 | |
| 2xw7 | NDP | Dihydrofolate reductase | / | 0.440 | |
| 3anl | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.440 | |
| 3cd2 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 3d78 | NBB | Pheromone-binding protein ASP1 | / | 0.440 | |
| 3ix8 | TX3 | Transcriptional activator protein LasR | / | 0.440 | |
| 3k4n | FAD | Pyranose 2-oxidase | / | 0.440 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.440 | |
| 3opd | HIE | Heat shock protein 83 | / | 0.440 | |
| 3p0f | BAU | Uridine phosphorylase 2 | 2.4.2.3 | 0.440 | |
| 3t3q | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.440 | |
| 3w5t | LHP | Vitamin D3 receptor | / | 0.440 | |
| 3zku | HCV | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 4bgi | I4I | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 4e6a | 0O9 | Mitogen-activated protein kinase 14 | / | 0.440 | |
| 4li7 | 1XP | Tankyrase-1 | 2.4.2.30 | 0.440 | |
| 4ok1 | 198 | Androgen receptor | / | 0.440 | |
| 4ruo | BIV | Vitamin D3 receptor A | / | 0.440 | |
| 4trj | 665 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 4x5j | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.440 |