sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4kpr | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 4kpr | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 1.374 | |
| 3qfa | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 1.292 | |
| 2x8g | FAD | Thioredoxin glutathione reductase | / | 1.274 | |
| 3ean | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 1.241 | |
| 2x8h | FAD | Thioredoxin glutathione reductase | / | 1.240 | |
| 1ges | FAD | Glutathione reductase | 1.8.1.7 | 1.192 | |
| 3dgh | FAD | Thioredoxin reductase 1, mitochondrial | 1.8.1.9 | 1.161 | |
| 3dgz | FAD | Thioredoxin reductase 2, mitochondrial | 1.8.1.9 | 1.155 | |
| 3dk9 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 1.141 | |
| 3grs | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 1.134 | |
| 1ger | FAD | Glutathione reductase | 1.8.1.7 | 1.130 | |
| 4la1 | FAD | Thioredoxin glutathione reductase | / | 1.124 | |
| 1h6v | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 1.123 | |
| 2nvk | FAD | Thioredoxin reductase 1, mitochondrial | 1.8.1.9 | 1.117 | |
| 2v6o | FAD | Thioredoxin glutathione reductase | / | 1.114 | |
| 2hqm | FAD | Glutathione reductase | 1.8.1.7 | 1.109 | |
| 4j57 | FAD | Thioredoxin reductase 2 | 1.8.1.9 | 1.108 | |
| 2wow | FAD | Trypanothione reductase | / | 1.101 | |
| 1gra | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 1.098 | |
| 2r9z | FAD | Glutathione amide reductase | / | 1.093 | |
| 3dk4 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 1.088 | |
| 2tpr | FAD | Trypanothione reductase | 1.8.1.12 | 1.086 | |
| 2zz0 | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 1.079 | |
| 2cfy | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 1.071 | |
| 2wba | FAD | Trypanothione reductase | 1.8.1.12 | 1.069 | |
| 2zzc | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 1.069 | |
| 1feb | FAD | Trypanothione reductase | 1.8.1.12 | 1.068 | |
| 2rab | FAD | Glutathione amide reductase | / | 1.055 | |
| 1get | FAD | Glutathione reductase | 1.8.1.7 | 1.051 | |
| 1k4q | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 1.051 | |
| 2jk6 | FAD | Trypanothione reductase | / | 1.046 | |
| 1fec | FAD | Trypanothione reductase | 1.8.1.12 | 1.044 | |
| 4nev | FAD | Trypanothione reductase | / | 1.041 | |
| 1typ | FAD | Trypanothione reductase | 1.8.1.12 | 1.038 | |
| 3dk8 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 1.033 | |
| 1gre | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 1.029 | |
| 1grb | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 1.027 | |
| 1fea | FAD | Trypanothione reductase | 1.8.1.12 | 1.024 | |
| 1geu | FAD | Glutathione reductase | 1.8.1.7 | 1.021 | |
| 1bwc | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 1.018 | |
| 4jq9 | FAD | Dihydrolipoyl dehydrogenase | / | 1.018 | |
| 1bzl | FAD | Trypanothione reductase | 1.8.1.12 | 1.017 | |
| 3qfb | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 1.015 | |
| 1tyt | FAD | Trypanothione reductase | 1.8.1.12 | 1.014 | |
| 3djg | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 1.014 | |
| 4gr1 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 1.014 | |
| 1gsn | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 1.006 | |
| 2wp5 | FAD | Trypanothione reductase | / | 1.005 | |
| 3sqp | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 1.003 | |
| 2eq7 | FAD | Dihydrolipoyl dehydrogenase | / | 0.995 | |
| 2gh5 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.988 | |
| 4dna | FAD | Probable glutathione reductase | / | 0.987 | |
| 2w0h | FAD | Trypanothione reductase | / | 0.986 | |
| 2j3n | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.981 | |
| 1grh | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.977 | |
| 2yqu | FAD | Dihydrolipoyl dehydrogenase | / | 0.974 | |
| 1grg | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.968 | |
| 1zx9 | FAD | Mercuric reductase | 1.16.1.1 | 0.964 | |
| 3dh9 | FAD | Thioredoxin reductase 1, mitochondrial | 1.8.1.9 | 0.963 | |
| 4b1b | FAD | Thioredoxin reductase | 1.8.1.9 | 0.955 | |
| 3djj | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.953 | |
| 2eq9 | FAD | Dihydrolipoyl dehydrogenase | / | 0.941 | |
| 4jdr | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.939 | |
| 4j56 | FAD | Thioredoxin reductase 2 | 1.8.1.9 | 0.938 | |
| 1dnc | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.928 | |
| 1zmd | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.927 | |
| 1gxf | FAD | Trypanothione reductase | 1.8.1.12 | 0.926 | |
| 2f5z | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.926 | |
| 1v59 | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.925 | |
| 2eq6 | FAD | Dihydrolipoyl dehydrogenase | / | 0.918 | |
| 1zk7 | FAD | Mercuric reductase | 1.16.1.1 | 0.911 | |
| 3rnm | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.909 | |
| 1zmc | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.904 | |
| 2qae | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.885 | |
| 1jeh | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.882 | |
| 1ebd | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.879 | |
| 3icr | FAD | Coenzyme A disulfide reductase | / | 0.873 | |
| 3oz2 | FAD | Digeranylgeranylglycerophospholipid reductase | / | 0.865 | |
| 3urh | FAD | Dihydrolipoyl dehydrogenase | / | 0.863 | |
| 5fs7 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.863 | |
| 5fs8 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.863 | |
| 2c3c | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.844 | |
| 3lad | FAD | Dihydrolipoyl dehydrogenase | / | 0.837 | |
| 1tde | FAD | Thioredoxin reductase | 1.8.1.9 | 0.834 | |
| 2eq8 | FAD | Dihydrolipoyl dehydrogenase | / | 0.834 | |
| 2qa1 | FAD | PgaE | / | 0.833 | |
| 3fbs | FAD | Oxidoreductase | / | 0.832 | |
| 1ojt | FAD | Dihydrolipoyl dehydrogenase | / | 0.828 | |
| 4jn9 | FAD | DepH | / | 0.826 | |
| 1f8w | FAD | NADH peroxidase | 1.11.1.1 | 0.822 | |
| 1lvl | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.819 | |
| 4ocg | FAD | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.819 | |
| 2gmh | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.815 | |
| 1lpf | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.814 | |
| 1mo9 | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.809 | |
| 1nhp | FAD | NADH peroxidase | 1.11.1.1 | 0.808 | |
| 1nhr | FAD | NADH peroxidase | 1.11.1.1 | 0.808 | |
| 3ics | FAD | Coenzyme A disulfide reductase | / | 0.806 | |
| 1n4u | FAE | Cholesterol oxidase | 1.1.3.6 | 0.802 | |
| 3cnj | FAD | Cholesterol oxidase | 1.1.3.6 | 0.802 | |
| 3ntd | FAD | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.802 | |
| 4rek | FAD | Cholesterol oxidase | 1.1.3.6 | 0.802 | |
| 4xwr | FAD | Cholesterol oxidase | 1.1.3.6 | 0.802 | |
| 1b8s | FAD | Cholesterol oxidase | 1.1.3.6 | 0.801 | |
| 1b4v | FAD | Cholesterol oxidase | 1.1.3.6 | 0.796 | |
| 1mok | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.796 | |
| 4nte | FAD | DepH | / | 0.796 | |
| 1fl2 | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.793 | |
| 1ijh | FAD | Cholesterol oxidase | 1.1.3.6 | 0.791 | |
| 1mxt | FAE | Cholesterol oxidase | 1.1.3.6 | 0.791 | |
| 4g6h | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.791 | |
| 4hb9 | FAD | Uncharacterized protein | / | 0.791 | |
| 1npx | FAD | NADH peroxidase | 1.11.1.1 | 0.788 | |
| 1n1p | FAD | Cholesterol oxidase | 1.1.3.6 | 0.786 | |
| 1n4w | FAD | Cholesterol oxidase | 1.1.3.6 | 0.786 | |
| 2gew | FAD | Cholesterol oxidase | 1.1.3.6 | 0.786 | |
| 3gyi | FAD | Cholesterol oxidase | 1.1.3.6 | 0.786 | |
| 3gyj | FAD | Cholesterol oxidase | 1.1.3.6 | 0.786 | |
| 4xxg | FAD | Cholesterol oxidase | 1.1.3.6 | 0.786 | |
| 1n4v | FAD | Cholesterol oxidase | 1.1.3.6 | 0.785 | |
| 3ab1 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.785 | |
| 4u2s | FDA | Cholesterol oxidase | 1.1.3.6 | 0.785 | |
| 4m52 | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.784 | |
| 3nta | FAD | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.782 | |
| 4o5q | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.782 | |
| 3b6d | FAE | Cholesterol oxidase | 1.1.3.6 | 0.781 | |
| 1onf | FAD | Glutathione reductase | 1.8.1.7 | 0.780 | |
| 4ccr | FAD | Thioredoxin reductase | / | 0.780 | |
| 3nt6 | FAD | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.777 | |
| 5buk | FAD | FADH2-dependent halogenase | / | 0.777 | |
| 4mih | FAD | Pyranose 2-oxidase | 1.1.3.10 | 0.773 | |
| 4u2t | FAD | Cholesterol oxidase | 1.1.3.6 | 0.773 | |
| 4ynt | FDA | Glucose oxidase, putative | / | 0.772 | |
| 4cnk | FAD | L-amino acid oxidase | / | 0.771 | |
| 4j33 | FAD | Kynurenine 3-monooxygenase | / | 0.771 | |
| 4fwf | FAD | Lysine-specific histone demethylase 1B | 1 | 0.765 | |
| 2i0z | FAD | NAD(FAD)-utilizing dehydrogenases | / | 0.764 | |
| 4up3 | FAD | Thioredoxin reductase | / | 0.763 | |
| 2zbw | FAD | Ferredoxin--NADP reductase | / | 0.762 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.762 | |
| 3g5s | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.762 | |
| 3lzw | FAD | Ferredoxin--NADP reductase 2 | 1.18.1.2 | 0.762 | |
| 3cox | FAD | Cholesterol oxidase | 1.1.3.6 | 0.761 | |
| 3cty | FAD | Probable thioredoxin reductase | / | 0.761 | |
| 1cbo | FAD | Cholesterol oxidase | 1.1.3.6 | 0.760 | |
| 4g6g | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.760 | |
| 4opg | FDA | Conserved Archaeal protein | / | 0.760 | |
| 2npx | FAD | NADH peroxidase | 1.11.1.1 | 0.759 | |
| 3ad9 | NAD | Subunit alpha of sarocosine oxidase | / | 0.758 | |
| 4gus | FAD | Lysine-specific histone demethylase 1B | 1 | 0.758 | |
| 2whd | FAD | Thioredoxin reductase | / | 0.757 | |
| 4gcm | FAD | Thioredoxin reductase | 1.8.1.9 | 0.757 | |
| 5dbj | FAD | FADH2-dependent halogenase PltA | / | 0.756 | |
| 4fwe | FAD | Lysine-specific histone demethylase 1B | 1 | 0.755 | |
| 2cdu | FAD | NADH oxidase | / | 0.754 | |
| 3lzx | FAD | Ferredoxin--NADP reductase 2 | 1.18.1.2 | 0.753 | |
| 4ccq | FAD | Thioredoxin reductase | / | 0.753 | |
| 4em4 | FAD | Coenzyme A disulfide reductase | / | 0.753 | |
| 1nhs | FAD | NADH peroxidase | 1.11.1.1 | 0.751 | |
| 3pl8 | FAD | Pyranose 2-oxidase | / | 0.750 | |
| 4a99 | FAD | TetX family tetracycline inactivation enzyme | / | 0.750 | |
| 4cbq | FAD | Thioredoxin reductase | / | 0.748 | |
| 4cy8 | FDA | 2-hydroxybiphenyl-3-monooxygenase | / | 0.747 | |
| 3nix | FAD | Flavoprotein/dehydrogenase | / | 0.746 | |
| 2xdo | FAD | TetX family tetracycline inactivation enzyme | / | 0.745 | |
| 3ict | FAD | Coenzyme A disulfide reductase | / | 0.745 | |
| 1vdc | FAD | Thioredoxin reductase 1, mitochondrial | 1.8.1.9 | 0.744 | |
| 2ywl | FAD | Thioredoxin reductase related protein | / | 0.744 | |
| 4opi | FDA | Conserved Archaeal protein | / | 0.744 | |
| 5j60 | FAD | Thioredoxin reductase | / | 0.744 | |
| 3f8d | FAD | NADH oxidase/thioredoxin reductase | / | 0.743 | |
| 1zy8 | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.742 | |
| 4qi5 | FAD | Cellobiose dehydrogenase | / | 0.742 | |
| 3cgc | FAD | Coenzyme A disulfide reductase | / | 0.740 | |
| 4opl | FDA | Conserved Archaeal protein | / | 0.740 | |
| 1joa | FAD | NADH peroxidase | 1.11.1.1 | 0.739 | |
| 3ic9 | FAD | Putative dihydrolipoamide dehydrogenase | / | 0.739 | |
| 1cc2 | FAD | Cholesterol oxidase | 1.1.3.6 | 0.738 | |
| 4j2w | FAD | Kynurenine 3-monooxygenase | / | 0.736 | |
| 3v76 | FDA | Uncharacterized protein | / | 0.735 | |
| 2igo | FAD | Pyranose 2-oxidase | / | 0.734 | |
| 2vou | FAD | 2,6-dihydroxypyridine 3-monooxygenase | 1.14.13.10 | 0.734 | |
| 4a65 | FAD | Thioredoxin reductase | / | 0.733 | |
| 4cnj | FAD | L-amino acid oxidase | / | 0.733 | |
| 4lii | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.733 | |
| 4x4j | FAD | Putative oxygenase | / | 0.732 | |
| 2b9w | FAD | Putative aminooxidase | / | 0.731 | |
| 2bac | FAD | Putative aminooxidase | / | 0.731 | |
| 4gut | FAD | Lysine-specific histone demethylase 1B | 1 | 0.731 | |
| 1xpq | FAD | Polyamine oxidase FMS1 | / | 0.729 | |
| 2a8x | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.729 | |
| 3g5q | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.729 | |
| 4ntc | FAD | Thioredoxin reductase gliT | / | 0.729 | |
| 1gv4 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.728 | |
| 1tdf | FAD | Thioredoxin reductase | 1.8.1.9 | 0.727 | |
| 3oc4 | FAD | Oxidoreductase, pyridine nucleotide-disulfide family | / | 0.727 | |
| 4fx9 | FAD | Coenzyme A disulfide reductase | 1.8.1.14 | 0.727 | |
| 1nhq | FAD | NADH peroxidase | 1.11.1.1 | 0.725 | |
| 2ign | FAD | Pyranose 2-oxidase | / | 0.725 | |
| 4h4r | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.725 | |
| 2bab | FAD | Putative aminooxidase | / | 0.722 | |
| 4opt | FDA | Conserved Archaeal protein | / | 0.722 | |
| 4o5u | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.721 | |
| 4opd | FDA | Conserved Archaeal protein | / | 0.720 | |
| 1ju2 | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.719 | |
| 4em3 | FAD | Coenzyme A disulfide reductase | / | 0.719 | |
| 4h4t | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.719 | |
| 4h4v | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.719 | |
| 4h4x | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.719 | |
| 4hsu | FAD | Lysine-specific histone demethylase 1B | 1 | 0.719 | |
| 2gqf | FAD | Uncharacterized protein HI_0933 | / | 0.718 | |
| 3lov | FAD | Protoporphyrinogen oxidase | / | 0.718 | |
| 4a6n | FAD | TetX family tetracycline inactivation enzyme | / | 0.717 | |
| 4bk3 | FAD | Probable salicylate monooxygenase | / | 0.717 | |
| 2b9y | FAD | Putative aminooxidase | / | 0.714 | |
| 4bk2 | FAD | Probable salicylate monooxygenase | / | 0.714 | |
| 4eqw | FAD | Coenzyme A disulfide reductase | / | 0.714 | |
| 1yqz | FAD | Coenzyme A disulfide reductase | / | 0.713 | |
| 2cvj | FAD | Thioredoxin reductase related protein | / | 0.711 | |
| 2b9x | FAD | Putative aminooxidase | / | 0.710 | |
| 4u2l | SFD | Cholesterol oxidase | 1.1.3.6 | 0.710 | |
| 2gr0 | FAD | Ferredoxin reductase | / | 0.709 | |
| 3fmw | FAD | Oxygenase | / | 0.709 | |
| 1k0j | FAD | p-hydroxybenzoate hydroxylase | / | 0.708 | |
| 2gqw | FAD | Ferredoxin reductase | / | 0.708 | |
| 3atq | FDA | Conserved Archaeal protein | / | 0.708 | |
| 4bjz | FAD | Probable salicylate monooxygenase | / | 0.708 | |
| 1m6i | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.707 | |
| 2x3n | FAD | Probable FAD-dependent monooxygenase | / | 0.707 | |
| 4h4p | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.707 | |
| 4opu | FDA | Conserved Archaeal protein | / | 0.707 | |
| 5eow | FAD | 6-hydroxynicotinate 3-monooxygenase | 1.14.13.114 | 0.707 | |
| 3cge | FAD | Coenzyme A disulfide reductase | / | 0.706 | |
| 2bry | FAD | [F-actin]-methionine sulfoxide oxidase MICAL1 | 1.14.13 | 0.705 | |
| 3atr | FDA | Conserved Archaeal protein | / | 0.705 | |
| 3cgb | FAD | Coenzyme A disulfide reductase | / | 0.704 | |
| 3bg7 | FAD | Pyranose 2-oxidase | / | 0.703 | |
| 4eqx | FAD | Coenzyme A disulfide reductase | / | 0.703 | |
| 5er0 | FAD | Uncharacterized NAD(FAD)-dependent dehydrogenase | / | 0.702 | |
| 1h7w | FAD | Dihydropyrimidine dehydrogenase [NADP(+)] | 1.3.1.2 | 0.701 | |
| 3itj | FAD | Thioredoxin reductase 1 | 1.8.1.9 | 0.701 | |
| 3k4n | FAD | Pyranose 2-oxidase | / | 0.701 | |
| 2xvf | FAD | Putative flavin-containing monooxygenase | / | 0.700 | |
| 3gdp | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.700 | |
| 4j34 | FAD | Kynurenine 3-monooxygenase | / | 0.700 | |
| 1d7y | FAD | Ferredoxin reductase | / | 0.699 | |
| 1gte | FAD | Dihydropyrimidine dehydrogenase [NADP(+)] | 1.3.1.2 | 0.699 | |
| 3ish | FAD | Thioredoxin reductase | 1.8.1.9 | 0.699 | |
| 3k4c | FAD | Pyranose 2-oxidase | / | 0.699 | |
| 4opc | FDA | Conserved Archaeal protein | / | 0.699 | |
| 4eqs | FAD | Coenzyme A disulfide reductase | / | 0.698 | |
| 1trb | FAD | Thioredoxin reductase | 1.8.1.9 | 0.697 | |
| 4z2t | FAD | 2-hydroxybiphenyl-3-monooxygenase | / | 0.697 | |
| 3klj | FAD | NADH-rubredoxin oxidoreductase | 1.18.1.1 | 0.696 | |
| 4g74 | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.696 | |
| 1gpe | FAD | Glucose oxidase | 1.1.3.4 | 0.695 | |
| 4a5l | FAD | Thioredoxin reductase | / | 0.695 | |
| 3d8x | FAD | Thioredoxin reductase 1 | 1.8.1.9 | 0.694 | |
| 4gur | FAD | Lysine-specific histone demethylase 1B | 1 | 0.694 | |
| 5fs6 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.694 | |
| 2gr3 | FAD | Ferredoxin reductase | / | 0.693 | |
| 5fs9 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.693 | |
| 2q7v | FAD | Thioredoxin reductase | / | 0.692 | |
| 2xyo | FAD | TetX family tetracycline inactivation enzyme | / | 0.691 | |
| 3gmb | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.691 | |
| 3rp8 | FAD | FAD-dependent urate hydroxylase | / | 0.691 | |
| 3sm8 | FNK | FAD-dependent catabolic D-arginine dehydrogenase DauA | / | 0.691 | |
| 3r9u | FAD | Thioredoxin reductase | / | 0.690 | |
| 2gv8 | FAD | Thiol-specific monooxygenase | 1.14.13 | 0.689 | |
| 5g3s | FDA | Flavin-dependent L-tryptophan oxidase VioA | / | 0.689 | |
| 1rp0 | AHZ | Thiamine thiazole synthase, chloroplastic | / | 0.686 | |
| 2bra | FAD | [F-actin]-methionine sulfoxide oxidase MICAL1 | 1.14.13 | 0.686 | |
| 3qvp | FAD | Glucose oxidase | 1.1.3.4 | 0.686 | |
| 4k2x | FAD | Polyketide oxygenase/hydroxylase | / | 0.685 | |
| 4ykg | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.685 | |
| 4ylf | FAD | Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit homolog | / | 0.685 | |
| 2c3d | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.684 | |
| 4ntd | FAD | Thioredoxin reductase | / | 0.684 | |
| 3cgd | FAD | Coenzyme A disulfide reductase | / | 0.683 | |
| 3lxd | FAD | FAD-dependent pyridine nucleotide-disulfide oxidoreductase | / | 0.682 | |
| 4h2n | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.680 | |
| 4ysh | FAD | Glycine oxidase | / | 0.679 | |
| 3fg2 | FAD | Putative rubredoxin reductase | / | 0.678 | |
| 4h4z | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.678 | |
| 4mo2 | FDA | UDP-galactopyranose mutase | / | 0.678 | |
| 3all | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.677 | |
| 3hdy | FDA | UDP-galactopyranose mutase | / | 0.677 | |
| 3he3 | FAD | UDP-galactopyranose mutase | / | 0.677 | |
| 2yg5 | FAD | Putrescine oxidase | / | 0.676 | |
| 3dme | FAD | Putative conserved exported protein | / | 0.675 | |
| 4xwz | FAD | Fructosyl amine:oxygen oxidoreductase | / | 0.675 | |
| 1yy5 | FAD | Polyamine oxidase FMS1 | / | 0.674 | |
| 3lsi | FAD | Pyranose 2-oxidase | / | 0.674 | |
| 1k0l | FAD | p-hydroxybenzoate hydroxylase | / | 0.672 | |
| 3ef6 | FAD | Toluene 1,2-dioxygenase system ferredoxin--NAD(+) reductase component | 1.18.1.3 | 0.672 | |
| 3ad9 | FAD | Subunit beta of sarcosine oxidase | / | 0.671 | |
| 1q1r | FAD | Putidaredoxin reductase | 1.18.1.5 | 0.670 | |
| 2qa2 | FAD | Polyketide oxygenase CabE | / | 0.670 | |
| 3hdy | FAD | UDP-galactopyranose mutase | / | 0.670 | |
| 1cf3 | FAD | Glucose oxidase | 1.1.3.4 | 0.669 | |
| 3bi5 | FAD | Polyamine oxidase FMS1 | / | 0.669 | |
| 3lsh | FAD | Pyranose 2-oxidase | / | 0.669 | |
| 4xbf | FAD | Lysine-specific histone demethylase 1A | 1 | 0.669 | |
| 5l3d | FAD | Lysine-specific histone demethylase 1A | 1 | 0.669 | |
| 1kif | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.668 | |
| 2e1m | FAD | L-glutamate oxidase | / | 0.668 | |
| 2v3a | FAD | Rubredoxin-NAD(+) reductase | 1.18.1.1 | 0.668 | |
| 2yvf | FAD | Ferredoxin reductase | / | 0.668 | |
| 3c4a | FAD | Protodeoxyviolaceinate monooxygenase | 1 | 0.668 | |
| 4b66 | FAD | L-ornithine N(5)-monooxygenase | / | 0.668 | |
| 4emj | FAD | Toluene 1,2-dioxygenase system ferredoxin--NAD(+) reductase component | 1.18.1.3 | 0.668 | |
| 4yry | FAD | Glutamate synthase, beta subunit | / | 0.667 | |
| 2fje | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.666 | |
| 3axb | FAD | Putative oxidoreductase | / | 0.666 | |
| 4b64 | FAD | L-ornithine N(5)-monooxygenase | / | 0.665 | |
| 1jnr | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.664 | |
| 1ve9 | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.664 | |
| 2yg4 | FAD | Putrescine oxidase | / | 0.663 | |
| 3nlc | FAD | Uncharacterized protein | / | 0.663 | |
| 3qvr | FAD | Glucose oxidase | 1.1.3.4 | 0.663 | |
| 3nn6 | FB0 | 6-hydroxy-L-nicotine oxidase | / | 0.662 | |
| 4jnq | FDA | Thioredoxin reductase | / | 0.662 | |
| 1djn | ADP | Trimethylamine dehydrogenase | 1.5.8.2 | 0.661 | |
| 4wct | FAD | Fructosyl amine:oxygen oxidoreductase | / | 0.661 | |
| 1cl0 | FAD | Thioredoxin reductase | 1.8.1.9 | 0.660 | |
| 1d7l | RFL | p-hydroxybenzoate hydroxylase | / | 0.660 | |
| 2ba9 | FAD | Putative aminooxidase | / | 0.660 | |
| 2c4c | FAD | [F-actin]-methionine sulfoxide oxidase MICAL1 | 1.14.13 | 0.660 | |
| 2q0l | FAD | Thioredoxin reductase | 1.8.1.9 | 0.660 | |
| 1tdn | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.659 | |
| 4bv6 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.659 | |
| 1q1w | FAD | Putidaredoxin reductase | 1.18.1.5 | 0.658 | |
| 2du8 | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.658 | |
| 2jb2 | FAD | L-amino acid oxidase | / | 0.658 | |
| 2q0k | FAD | Thioredoxin reductase | 1.8.1.9 | 0.658 | |
| 4yjd | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.658 | |
| 3t37 | FAD | Pyridoxine 4-oxidase | / | 0.657 | |
| 4j36 | FAD | Kynurenine 3-monooxygenase | / | 0.657 | |
| 1d4d | FAD | Fumarate reductase flavoprotein subunit | 1.3.5.4 | 0.656 | |
| 2ar8 | FAD | Flavin-dependent tryptophan halogenase PrnA | 1.14.19.9 | 0.656 | |
| 3if9 | FAD | Glycine oxidase | 1.4.3.19 | 0.656 | |
| 4mok | FAD | Pyranose 2-oxidase | / | 0.656 | |
| 2fjd | SFD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.655 | |
| 4k5r | FAD | Oxygenase | / | 0.655 | |
| 1cjc | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.654 | |
| 4jy2 | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.654 | |
| 4tm1 | FDA | KtzI | / | 0.654 | |
| 1rsg | FAD | Polyamine oxidase FMS1 | / | 0.653 | |
| 1tdo | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.653 | |
| 2gr1 | FAD | Ferredoxin reductase | / | 0.653 | |
| 2gvc | FAD | Thiol-specific monooxygenase | 1.14.13 | 0.653 | |
| 2h94 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.653 | |
| 2yg7 | FAD | Putrescine oxidase | / | 0.653 | |
| 3gsi | FAD | Dimethylglycine oxidase | 1.5.3.10 | 0.653 | |
| 4c3x | FAD | 3-ketosteroid dehydrogenase | / | 0.653 | |
| 4gdp | FAD | Polyamine oxidase FMS1 | / | 0.653 | |
| 4h2p | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.653 | |
| 4h50 | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.653 | |
| 5eb5 | FAD | (R)-mandelonitrile lyase 1 | 4.1.2.10 | 0.653 | |
| 3gwd | FAD | Cyclohexanone monooxygenase | / | 0.652 | |
| 4fwj | FAD | Lysine-specific histone demethylase 1B | 1 | 0.652 | |
| 3gd3 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.651 | |
| 3ukk | FAD | UDP-galactopyranose mutase | / | 0.651 | |
| 4usr | FAD | Monooxygenase | / | 0.651 | |
| 3nyc | FAD | FAD-dependent catabolic D-arginine dehydrogenase DauA | / | 0.650 | |
| 4dsg | FAD | Uncharacterized protein | / | 0.650 |