sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4cgd | 8P3 | Integrase |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 4cgd | 8P3 | Integrase | / | 1.000 | |
| 4cec | 2SS | Integrase | / | 0.626 | |
| 4ceq | QCH | Integrase | / | 0.622 | |
| 4cgi | NZL | Integrase | / | 0.619 | |
| 4ce9 | O3N | Integrase | / | 0.617 | |
| 4cjf | RVN | Integrase | / | 0.599 | |
| 3zsq | O4N | Integrase | / | 0.597 | |
| 4ces | NFW | Integrase | / | 0.595 | |
| 4cgg | K5Q | Integrase | / | 0.595 | |
| 4cf8 | V7H | Integrase | / | 0.593 | |
| 4cfa | WOP | Integrase | / | 0.593 | |
| 4ceo | G0T | Integrase | / | 0.591 | |
| 4cj5 | 4VW | Integrase | / | 0.590 | |
| 3zt0 | ZT0 | Integrase | / | 0.589 | |
| 4cfd | S8Y | Integrase | / | 0.589 | |
| 4ck2 | NVU | Integrase | / | 0.588 | |
| 4cef | D0T | Integrase | / | 0.583 | |
| 3zsx | N44 | Integrase | / | 0.582 | |
| 4cf0 | O5U | Integrase | / | 0.582 | |
| 3zsr | O3N | Integrase | / | 0.579 | |
| 4cez | O3N | Integrase | / | 0.579 | |
| 4cf2 | 3GM | Integrase | / | 0.576 | |
| 4cif | JDX | Integrase | / | 0.576 | |
| 3zsw | ZSW | Integrase | / | 0.575 | |
| 4chy | C5Q | Integrase | / | 0.575 | |
| 4cj3 | E4F | Integrase | / | 0.574 | |
| 3zsz | OM2 | Integrase | / | 0.573 | |
| 4cea | ZSW | Integrase | / | 0.573 | |
| 4cfc | 7NV | Integrase | / | 0.571 | |
| 4ced | 9NS | Integrase | / | 0.570 | |
| 3zsy | OM3 | Integrase | / | 0.568 | |
| 4cgj | NZL | Integrase | / | 0.566 | |
| 4cie | Y7N | Integrase | / | 0.566 | |
| 4cj4 | S3G | Integrase | / | 0.566 | |
| 4cig | X0P | Integrase | / | 0.563 | |
| 4cjr | FYM | Integrase | / | 0.562 | |
| 4cje | Q31 | Integrase | / | 0.561 | |
| 4cee | B0T | Integrase | / | 0.559 | |
| 3zt1 | OM1 | Integrase | / | 0.556 | |
| 4cer | VL4 | Integrase | / | 0.555 | |
| 4cjp | 4D2 | Integrase | / | 0.552 | |
| 4cf1 | IY7 | Integrase | / | 0.549 | |
| 4cfb | OM3 | Integrase | / | 0.549 | |
| 4cju | JNS | Integrase | / | 0.549 | |
| 3zt2 | ZT2 | Integrase | / | 0.548 | |
| 3zt3 | ZT4 | Integrase | / | 0.548 | |
| 4chq | CWU | Integrase | / | 0.547 | |
| 4ck3 | K1T | Integrase | / | 0.545 | |
| 4cjq | VXO | Integrase | / | 0.543 | |
| 3zsv | ZSV | Integrase | / | 0.542 | |
| 4ceb | ZSV | Integrase | / | 0.542 | |
| 4cgh | LOZ | Integrase | / | 0.540 | |
| 4ck1 | OM1 | Integrase | / | 0.539 | |
| 3zcm | PX3 | Integrase | / | 0.534 | |
| 4cjk | H39 | Integrase | / | 0.532 | |
| 4cjs | L0Y | Integrase | / | 0.522 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.508 | |
| 4cgf | UJ6 | Integrase | / | 0.502 | |
| 2rh9 | IGP | Tryptophan synthase alpha chain | / | 0.496 | |
| 1jtv | TES | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.493 | |
| 1h74 | AGS | Homoserine kinase | 2.7.1.39 | 0.491 | |
| 1kfb | IGP | Tryptophan synthase alpha chain | / | 0.490 | |
| 1a59 | COA | 2-methylcitrate synthase | / | 0.489 | |
| 1rx8 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.486 | |
| 2rhg | IGP | Tryptophan synthase alpha chain | / | 0.486 | |
| 2nru | T12 | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.484 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.484 | |
| 1ia1 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.482 | |
| 1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.482 | |
| 1pzh | NAD | Lactate dehydrogenase | / | 0.482 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.482 | |
| 1k8y | 13P | Tryptophan synthase alpha chain | / | 0.481 | |
| 4cr8 | NAD | N-acylmannosamine 1-dehydrogenase | 1.1.1.233 | 0.481 | |
| 1rx8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.480 | |
| 4c02 | TAK | Activin receptor type-1 | 2.7.11.30 | 0.479 | |
| 3gbu | ATP | Uncharacterized sugar kinase PH1459 | 2.7.1 | 0.478 | |
| 2ohv | NHL | Glutamate racemase | / | 0.476 | |
| 3oib | FDA | Putative acyl-CoA dehydrogenase | / | 0.476 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.475 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.474 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.474 | |
| 2e9n | 76A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.474 | |
| 2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.474 | |
| 3nxx | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.474 | |
| 3slk | NDP | Polyketide synthase extender module 2 | / | 0.474 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.474 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.473 | |
| 2rg6 | 287 | Mitogen-activated protein kinase 14 | / | 0.473 | |
| 3giy | FMN | (S)-mandelate dehydrogenase | 1.1.99.31 | 0.473 | |
| 3p82 | FMN | Pentaerythritol tetranitrate reductase | / | 0.473 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.472 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.472 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.471 | |
| 1kfc | IPL | Tryptophan synthase alpha chain | / | 0.471 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.471 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.471 | |
| 2e9u | A25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.470 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.470 | |
| 4aot | GW8 | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.470 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.469 | |
| 3dt1 | P40 | Mitogen-activated protein kinase 14 | / | 0.469 | |
| 3p67 | FMN | Pentaerythritol tetranitrate reductase | / | 0.469 | |
| 3p74 | FMN | Pentaerythritol tetranitrate reductase | / | 0.469 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.469 | |
| 5ar4 | SB2 | Receptor-interacting serine/threonine-protein kinase 2 | 2.7.11.1 | 0.469 | |
| 1y57 | MPZ | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.468 | |
| 4obu | PLP | Pyridoxal-dependent decarboxylase domain protein | / | 0.468 | |
| 1j49 | NAD | D-lactate dehydrogenase | 1.1.1.28 | 0.467 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.467 | |
| 2d29 | FAD | Acyl-CoA dehydrogenase | / | 0.467 | |
| 3f1k | NAP | Uncharacterized oxidoreductase YciK | 1 | 0.467 | |
| 1crb | RTL | Retinol-binding protein 1 | / | 0.466 | |
| 1h74 | ADP | Homoserine kinase | 2.7.1.39 | 0.466 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.466 | |
| 2aa0 | MTP | Adenosine kinase | 2.7.1.20 | 0.466 | |
| 3nr4 | PYV | Abscisic acid receptor PYL2 | / | 0.466 | |
| 4fiz | CUE | 17beta-hydroxysteroid dehydrogenase | / | 0.466 | |
| 4hbg | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.466 | |
| 4hle | 17V | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.466 | |
| 4kip | 1R9 | Mitogen-activated protein kinase 14 | / | 0.466 | |
| 4ros | APR | Malate dehydrogenase | / | 0.466 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.465 | |
| 1sow | NAD | L-lactate dehydrogenase | 1.1.1.27 | 0.465 | |
| 1z6t | ADP | Apoptotic protease-activating factor 1 | / | 0.465 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.465 | |
| 3tqa | NDP | Dihydrofolate reductase | / | 0.465 | |
| 3tri | NAP | Pyrroline-5-carboxylate reductase | / | 0.465 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.464 | |
| 1rx1 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 1u4o | NDD | L-lactate dehydrogenase | 1.1.1.27 | 0.464 | |
| 2a92 | NAI | L-lactate dehydrogenase | / | 0.464 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.464 | |
| 5hwr | COA | Hydroxymethylglutaryl-CoA synthase | / | 0.464 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.463 | |
| 1s3v | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
| 1sny | NAP | LD36273p | / | 0.463 | |
| 2y6o | 1N1 | Ephrin type-A receptor 4 | 2.7.10.1 | 0.463 | |
| 3a14 | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.463 | |
| 3mg3 | ECH | Orange carotenoid-binding protein | / | 0.463 | |
| 3mtf | A3F | Activin receptor type-1 | 2.7.11.30 | 0.463 | |
| 4k28 | NAD | Shikimate dehydrogenase family protein | / | 0.463 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.463 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.462 | |
| 1szm | BI4 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.462 | |
| 1u2g | APR | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.462 | |
| 2hk9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.462 | |
| 2tps | TPS | Thiamine-phosphate synthase | / | 0.462 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.462 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.462 | |
| 4an4 | DUD | Putative glycosyl transferase | / | 0.462 | |
| 5itz | LOC | Tubulin beta-2B chain | / | 0.462 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.461 | |
| 2c27 | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.461 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.461 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 3mvm | 39P | Mitogen-activated protein kinase 14 | / | 0.461 | |
| 3r04 | UNQ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.461 | |
| 3up0 | D7S | aceDAF-12 | / | 0.461 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.461 | |
| 4b8w | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.461 | |
| 4ft7 | H3K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.461 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.460 | |
| 1pow | FAD | Pyruvate oxidase | 1.2.3.3 | 0.460 | |
| 2bfy | H1N | Aurora kinase B-A | 2.7.11.1 | 0.460 | |
| 4e8y | IHA | D-beta-D-heptose 7-phosphate kinase | / | 0.460 | |
| 4eag | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.460 | |
| 5iqi | GNP | Bifunctional AAC/APH | 2.3.1 | 0.460 | |
| 1al8 | DHP | Peroxisomal (S)-2-hydroxy-acid oxidase | 1.1.3.15 | 0.459 | |
| 1p0h | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.459 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.459 | |
| 1wwk | NAD | 307aa long hypothetical phosphoglycerate dehydrogenase | / | 0.459 | |
| 1z0a | GDP | Ras-related protein Rab-2A | / | 0.459 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.459 | |
| 2j5x | GSP | ADP-ribosylation factor 6 | / | 0.459 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.459 | |
| 3bbr | BHY | Glutamate receptor 2 | / | 0.459 | |
| 3vjo | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.459 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.459 | |
| 3vtb | TKA | Vitamin D3 receptor | / | 0.459 | |
| 4e2d | FMN | Dehydrogenase | / | 0.459 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.459 | |
| 4nd4 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.459 | |
| 1szg | FNS | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.458 | |
| 1tj0 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.458 | |
| 2aqh | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.458 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.458 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.458 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.458 | |
| 3b6z | CO7 | Enoyl reductase LovC | 1 | 0.458 | |
| 3iae | D7K | Benzaldehyde lyase | / | 0.458 | |
| 3mpt | 1GK | Mitogen-activated protein kinase 14 | / | 0.458 | |
| 3poz | 03P | Epidermal growth factor receptor | 2.7.10.1 | 0.458 | |
| 4bdh | WVI | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.458 | |
| 1ib6 | NAD | Malate dehydrogenase | / | 0.457 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.457 | |
| 1kc1 | NDP | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.457 | |
| 1ot7 | CHC | Bile acid receptor | / | 0.457 | |
| 2fhn | BNI | Avidin-related protein 4/5 | / | 0.457 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.457 | |
| 3hdm | MMG | Serine/threonine-protein kinase Sgk1 | 2.7.11.1 | 0.457 | |
| 3jun | AKD | Phenazine biosynthesis protein A/B | / | 0.457 | |
| 4btj | ADP | Tau-tubulin kinase 1 | 2.7.11.1 | 0.457 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.457 | |
| 4ft5 | H2K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.457 | |
| 5hwq | CAA | Hydroxymethylglutaryl-CoA synthase | / | 0.457 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 1eio | GCH | Gastrotropin | / | 0.456 | |
| 1txt | CAA | HMG-CoA synthase | / | 0.456 | |
| 1x15 | NAD | NAD(P) transhydrogenase subunit alpha | 1.6.1.2 | 0.456 | |
| 2bal | PQA | Mitogen-activated protein kinase 14 | / | 0.456 | |
| 2bbw | GP5 | Adenylate kinase 4, mitochondrial | / | 0.456 | |
| 2ekl | NAD | D-3-phosphoglycerate dehydrogenase | / | 0.456 | |
| 2xvq | 9DS | Serum albumin | / | 0.456 | |
| 3fnl | SHA | Lactoperoxidase | / | 0.456 | |
| 3gu8 | 3GU | Death-associated protein kinase 1 | 2.7.11.1 | 0.456 | |
| 3icr | COA | Coenzyme A disulfide reductase | / | 0.456 | |
| 4f65 | 0S9 | Fibroblast growth factor receptor 1 | / | 0.456 | |
| 4gj3 | 0XP | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.456 | |
| 4y8w | STR | Steroid 21-hydroxylase | / | 0.456 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.455 | |
| 1m9a | GTX | Glutathione S-transferase class-mu 26 kDa isozyme | 2.5.1.18 | 0.455 | |
| 1rx6 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 1uxj | NAD | Malate dehydrogenase | / | 0.455 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.455 | |
| 2qtv | GNP | Small COPII coat GTPase SAR1 | 3.6.5 | 0.455 | |
| 3iph | G11 | Mitogen-activated protein kinase 14 | / | 0.455 | |
| 3qls | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 4oh4 | ANP | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.455 | |
| 4p8r | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.455 | |
| 4u07 | ATP | Adenosine monophosphate-protein transferase FICD | 2.7.7.n1 | 0.455 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.454 | |
| 1dyh | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 1fdt | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.454 | |
| 1i7p | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.454 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.454 | |
| 2g2z | COZ | Malonyl CoA-acyl carrier protein transacylase | 2.3.1.39 | 0.454 | |
| 2hc4 | VDX | Vitamin D3 receptor A | / | 0.454 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.454 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.454 | |
| 3iw1 | ASD | Steroid C26-monooxygenase | 1.14.13.141 | 0.454 | |
| 3r7e | X88 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
| 3r9u | FAD | Thioredoxin reductase | / | 0.454 | |
| 4bkz | 1WS | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.454 | |
| 4bzn | UGX | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.454 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.454 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.454 | |
| 4g2r | H1L | Probable propionyl-CoA carboxylase beta chain 6 | 6.4.1.3 | 0.454 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.454 | |
| 4u9a | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.454 | |
| 5e8w | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.454 | |
| 5itz | GTP | Tubulin alpha-1B chain | / | 0.454 | |
| 1bxk | NAD | dTDP-glucose 4,6-dehydratase 2 | / | 0.453 | |
| 1k74 | 544 | Peroxisome proliferator-activated receptor gamma | / | 0.453 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.453 | |
| 1ykd | CMP | Adenylate cyclase | / | 0.453 | |
| 2gnh | H52 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.453 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.453 | |
| 2yxu | ATP | Pyridoxal kinase | 2.7.1.35 | 0.453 | |
| 3daf | FEG | 5,10-methenyltetrahydromethanopterin hydrogenase | 1.12.98.2 | 0.453 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.453 | |
| 3fly | FLY | Mitogen-activated protein kinase 14 | / | 0.453 | |
| 3lki | ATP | Fructokinase | / | 0.453 | |
| 3w32 | W32 | Epidermal growth factor receptor | 2.7.10.1 | 0.453 | |
| 4a84 | DXC | Major pollen allergen Bet v 1-A | / | 0.453 | |
| 4o71 | CPB | Bromodomain-containing protein 4 | / | 0.453 | |
| 4wdb | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.453 | |
| 5a3b | APR | SIR2 family protein | / | 0.453 | |
| 5fwn | NAP | Putative dehydrogenase | / | 0.453 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.452 | |
| 1di8 | DTQ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.452 | |
| 1hyg | NAP | L-2-hydroxycarboxylate dehydrogenase (NAD(P)(+)) | / | 0.452 | |
| 1pzf | A3D | Lactate dehydrogenase | / | 0.452 | |
| 1zrz | BI1 | Protein kinase C iota type | 2.7.11.13 | 0.452 | |
| 2bri | ANP | Uridylate kinase | 2.7.4.22 | 0.452 | |
| 2npa | MMB | Peroxisome proliferator-activated receptor alpha | / | 0.452 | |
| 2pg0 | FAD | Acyl-CoA dehydrogenase | / | 0.452 | |
| 2v9j | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.452 | |
| 2w9h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 3i5z | Z48 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.452 | |
| 3maa | FKP | Adenylate cyclase type 2 | / | 0.452 | |
| 3maa | FKP | Adenylate cyclase type 5 | / | 0.452 | |
| 3mkn | DNB | Pyrimidine-specific ribonucleoside hydrolase RihB | / | 0.452 | |
| 3t3r | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.452 | |
| 4hbm | 0Y7 | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.452 | |
| 4tmc | FMN | Old yellow enzyme | / | 0.452 | |
| 4wh2 | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.452 | |
| 1dyj | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1osv | CHC | Bile acid receptor | / | 0.451 | |
| 1p31 | EPU | UDP-N-acetylmuramate--L-alanine ligase | 6.3.2.8 | 0.451 | |
| 1q5k | TMU | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.451 | |
| 1upc | TPP | N(2)-(2-carboxyethyl)arginine synthase | / | 0.451 | |
| 1x2h | LPA | Lipoate-protein ligase A | 6.3.1.20 | 0.451 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.451 | |
| 2c1b | CQP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.451 | |
| 2dhf | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 2np8 | CC3 | Aurora kinase A | 2.7.11.1 | 0.451 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.451 | |
| 3ijd | C2F | Methylenetetrahydrofolate reductase | / | 0.451 | |
| 3lfm | 3DT | Alpha-ketoglutarate-dependent dioxygenase FTO | / | 0.451 | |
| 3ttj | JBI | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.451 | |
| 4fv7 | E94 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.451 | |
| 4h8n | NDP | NADPH-dependent conjugated polyketone reductase C2 | / | 0.451 | |
| 4imo | PWZ | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.451 | |
| 4itf | TFY | Vitamin D3 receptor | / | 0.451 | |
| 1bxs | NAD | Retinal dehydrogenase 1 | 1.2.1.36 | 0.450 | |
| 1cjt | FOK | Adenylate cyclase type 2 | / | 0.450 | |
| 1cjt | FOK | Adenylate cyclase type 5 | / | 0.450 | |
| 1ha3 | MAU | Elongation factor Tu-A | / | 0.450 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1t88 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 2a84 | ATP | Pantothenate synthetase | 6.3.2.1 | 0.450 | |
| 2v59 | LZK | Biotin carboxylase | 6.3.4.14 | 0.450 | |
| 3cy2 | MB9 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.450 | |
| 3flk | NAI | Tartrate dehydrogenase/decarboxylase | 1.1.1.93 | 0.450 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.450 | |
| 3ule | C69 | Actin-related protein 3 | / | 0.450 | |
| 3up4 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.450 | |
| 3w0h | W12 | Vitamin D3 receptor | / | 0.450 | |
| 4z63 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.450 | |
| 5cyo | GDP | Septin-9 | / | 0.450 | |
| 5hwo | HMG | Hydroxymethylglutaryl-CoA synthase | / | 0.450 | |
| 1csc | CMC | Citrate synthase, mitochondrial | 2.3.3.1 | 0.449 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.449 | |
| 1e6w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.449 | |
| 1pzg | A3D | Lactate dehydrogenase | / | 0.449 | |
| 1zc3 | GNP | Ras-related protein Ral-A | / | 0.449 | |
| 2itu | ITQ | Epidermal growth factor receptor | 2.7.10.1 | 0.449 | |
| 2wuf | KEM | 4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase | 3.7.1.17 | 0.449 | |
| 3of2 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.449 | |
| 3sp6 | IL2 | Peroxisome proliferator-activated receptor alpha | / | 0.449 | |
| 3vfq | AR6 | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.449 | |
| 4bzo | 676 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.449 | |
| 4cjw | CBJ | Integrase | / | 0.449 | |
| 4h4y | NAP | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.449 | |
| 4i6g | FAD | Cryptochrome-2 | / | 0.449 | |
| 4q72 | FAD | Bifunctional protein PutA | / | 0.449 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.449 | |
| 1cbf | SAH | Cobalt-precorrin-4 C(11)-methyltransferase | 2.1.1.271 | 0.448 | |
| 1kqu | BR4 | Phospholipase A2, membrane associated | / | 0.448 | |
| 1msm | JE2 | Gag-Pol polyprotein | 3.4.23.16 | 0.448 | |
| 1p9w | ANP | Type II secretion system protein E | / | 0.448 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.448 | |
| 2fto | TMP | Thymidylate synthase | / | 0.448 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.448 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.448 | |
| 2v4l | ABJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.448 | |
| 2ww4 | ADP | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | 2.7.1.148 | 0.448 | |
| 2z3u | CRR | Cytochrome P450 | / | 0.448 | |
| 3bgb | LJG | Gag-Pol polyprotein | 3.4.23.16 | 0.448 | |
| 3so9 | 017 | Pol protein | / | 0.448 | |
| 3vt3 | VDX | Vitamin D3 receptor | / | 0.448 | |
| 3w0y | DS4 | Vitamin D3 receptor | / | 0.448 | |
| 3zw9 | NAD | Peroxisomal bifunctional enzyme | 1.1.1.35 | 0.448 | |
| 4c34 | STU | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.448 | |
| 4jld | ADP | Adenylate kinase | / | 0.448 | |
| 4m6j | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.448 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.448 | |
| 5ecc | NAP | Dehydrofolate reductase type I | / | 0.448 | |
| 1bwk | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.447 | |
| 1d8m | BBH | Stromelysin-1 | 3.4.24.17 | 0.447 | |
| 1diu | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1fwk | ADP | Homoserine kinase | 2.7.1.39 | 0.447 | |
| 1m75 | CAA | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.447 | |
| 1mzs | 669 | 3-oxoacyl-[acyl-carrier-protein] synthase 3 | / | 0.447 | |
| 2feu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 2qbl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 2vtt | LZD | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 2w3b | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.447 | |
| 2yoz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.447 | |
| 3au8 | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic | 1.1.1.267 | 0.447 | |
| 3dv3 | MEK | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.447 | |
| 3tki | S25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.447 | |
| 3w0j | T08 | Vitamin D3 receptor | / | 0.447 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.447 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.447 | |
| 4c3f | 7KW | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.447 | |
| 4dja | FAD | (6-4) photolyase | / | 0.447 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.447 | |
| 4euf | NAD | Trans-2-enoyl-CoA reductase [NADH] | / | 0.447 | |
| 4ew2 | DXY | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.447 | |
| 4fhi | 0S4 | Vitamin D3 receptor A | / | 0.447 | |
| 4fhk | 0U0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.447 | |
| 4g8z | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 5ez7 | FAD | Probable FAD-dependent oxidoreductase PA4991 | / | 0.447 | |
| 1dr2 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1fml | RTL | Retinol dehydratase | / | 0.446 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.446 | |
| 1phh | FAD | p-hydroxybenzoate hydroxylase | / | 0.446 | |
| 1u33 | LM2 | Pancreatic alpha-amylase | / | 0.446 | |
| 1vzb | UMP | Thymidylate synthase | / | 0.446 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.446 | |
| 1zxm | ANP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.446 | |
| 2clq | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.446 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.446 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.446 | |
| 2m56 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 2o7p | NAP | Riboflavin biosynthesis protein RibD | / | 0.446 | |
| 2xrw | ANP | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.446 | |
| 3ac3 | KSH | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.446 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.446 | |
| 3d7k | D7K | Benzaldehyde lyase | / | 0.446 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.446 | |
| 3gyu | DL7 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.446 | |
| 3hx4 | ANP | Calmodulin-domain protein kinase 1 | / | 0.446 | |
| 3koo | 24D | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.446 | |
| 3vid | 4TT | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.446 | |
| 4anv | 751 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.446 | |
| 4b4o | NDP | Epimerase family protein SDR39U1 | / | 0.446 | |
| 4cuk | NAI | D-lactate dehydrogenase | / | 0.446 | |
| 4dpt | AGS | Mevalonate diphosphate decarboxylase | / | 0.446 | |
| 4fod | 0UV | ALK tyrosine kinase receptor | 2.7.10.1 | 0.446 | |
| 4ite | TEY | Vitamin D3 receptor | / | 0.446 | |
| 4jic | FMN | GTN Reductase | / | 0.446 | |
| 4l4x | NDP | AmphI | / | 0.446 | |
| 4nxu | ADP | Mitochondrial dynamics protein MID51 | / | 0.446 | |
| 4r3k | COA | N-alpha-acetyltransferase | 2.3.1 | 0.446 | |
| 5e8y | STU | TGF-beta receptor type-2 | 2.7.11.30 | 0.446 | |
| 1aj8 | COA | Citrate synthase | / | 0.445 | |
| 1db4 | 8IN | Phospholipase A2, membrane associated | / | 0.445 | |
| 1ipe | NDP | Tropinone reductase 2 | 1.1.1.236 | 0.445 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.445 | |
| 1n2s | NAI | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.445 | |
| 1ol7 | ADP | Aurora kinase A | 2.7.11.1 | 0.445 | |
| 1q6t | 600 | Tyrosine-protein phosphatase non-receptor type 1 | 3.1.3.48 | 0.445 | |
| 1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.445 | |
| 2ahr | NAP | Pyrroline-5-carboxylate reductase | / | 0.445 | |
| 2b7a | IZA | Tyrosine-protein kinase JAK2 | / | 0.445 | |
| 2exc | JNK | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.445 | |
| 2vz6 | FEF | Calcium/calmodulin-dependent protein kinase type II subunit alpha | 2.7.11.17 | 0.445 | |
| 3a3b | RBF | Lumazine protein | / | 0.445 | |
| 3bv3 | P39 | Mitogen-activated protein kinase 14 | / | 0.445 | |
| 3cx6 | GDP | Guanine nucleotide-binding protein subunit alpha-13 | / | 0.445 | |
| 3d57 | 4HY | Thyroid hormone receptor beta | / | 0.445 | |
| 3eku | CY9 | Actin-5C | / | 0.445 | |
| 3g70 | A5T | Renin | 3.4.23.15 | 0.445 | |
| 3gka | FMN | N-ethylmaleimide reductase | / | 0.445 | |
| 3irm | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.445 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.445 | |
| 3otf | CMP | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 | / | 0.445 | |
| 4e93 | GUI | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.445 | |
| 4fqs | LYA | Thymidylate synthase ThyA | / | 0.445 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.445 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 4gh5 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.445 | |
| 4ure | 1PS | Cyclohexanol dehydrogenase | / | 0.445 | |
| 4y93 | 746 | Tyrosine-protein kinase | / | 0.445 | |
| 5iu4 | ZMA | Adenosine receptor A2a | / | 0.445 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1dr5 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 2dfv | NAD | L-threonine 3-dehydrogenase | / | 0.444 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.444 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.444 | |
| 2ihv | TPP | N(2)-(2-carboxyethyl)arginine synthase | / | 0.444 | |
| 2iw8 | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 2vwz | 7X6 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.444 | |
| 2xvu | 9DN | Serum albumin | / | 0.444 | |
| 3apf | BMW | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.444 | |
| 3fun | 798 | Leukotriene A-4 hydrolase | 3.3.2.6 | 0.444 | |
| 3p8j | FMN | Pentaerythritol tetranitrate reductase | / | 0.444 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.444 | |
| 3s7a | 684 | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 3w0a | DS5 | Vitamin D3 receptor | / | 0.444 | |
| 3w0c | 6DS | Vitamin D3 receptor | / | 0.444 | |
| 3zbs | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.444 | |
| 4ajn | 88V | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.444 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.444 | |
| 4nxx | GDP | Mitochondrial dynamics protein MID51 | / | 0.444 | |
| 4otp | ADP | Serine/threonine-protein kinase RIO1 | 2.7.11.1 | 0.444 | |
| 4qms | 1N1 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.444 | |
| 5a9s | NAP | Putative dehydrogenase | / | 0.444 | |
| 5awm | ANP | Stress-activated protein kinase JNK | 2.7.11.24 | 0.444 | |
| 1a72 | PAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.443 | |
| 1dra | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1e8z | STU | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.443 | |
| 1h72 | ANP | Homoserine kinase | 2.7.1.39 | 0.443 | |
| 1k7f | IAV | Tryptophan synthase alpha chain | / | 0.443 | |
| 1t2d | NAD | L-lactate dehydrogenase | 1.1.1.27 | 0.443 | |
| 1ur5 | NAD | Malate dehydrogenase | / | 0.443 | |
| 1xts | GTP | GTP-binding protein Rheb | / | 0.443 | |
| 1zth | ADP | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.443 | |
| 2brm | DFZ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.443 | |
| 2tct | CTC | Tetracycline repressor protein class D | / | 0.443 | |
| 2wih | P48 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 2ylz | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.443 | |
| 2zla | VDB | Vitamin D3 receptor | / | 0.443 | |
| 3aut | NAI | Glucose 1-dehydrogenase 4 | 1.1.1.47 | 0.443 | |
| 3br3 | ET | HTH-type transcriptional regulator QacR | / | 0.443 | |
| 3cid | 318 | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 3f7b | AG5 | Carbonic anhydrase 4 | 4.2.1.1 | 0.443 | |
| 3g5q | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.443 | |
| 3gfb | NAD | L-threonine 3-dehydrogenase | / | 0.443 | |
| 3h3c | P1E | Protein-tyrosine kinase 2-beta | 2.7.10.2 | 0.443 | |
| 3il1 | B5D | Glutamate receptor 2 | / | 0.443 | |
| 4dqu | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 4eu9 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.443 | |
| 4kug | NAD | 3-hydroxybutyryl-CoA dehydrogenase | / | 0.443 | |
| 4rvn | COA | Phenylacetate-coenzyme A ligase | / | 0.443 | |
| 4wdg | A2P | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.443 | |
| 1fk8 | NAD | 3-alpha-hydroxysteroid dehydrogenase/carbonyl reductase | 1.1.1.50 | 0.442 | |
| 1gqt | ACP | Ribokinase | / | 0.442 | |
| 1guy | NAD | Malate dehydrogenase | / | 0.442 | |
| 1h73 | ANP | Homoserine kinase | 2.7.1.39 | 0.442 | |
| 1i7g | AZ2 | Peroxisome proliferator-activated receptor alpha | / | 0.442 | |
| 1ie3 | NAD | Malate dehydrogenase | / | 0.442 | |
| 1nqo | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.442 | |
| 1x14 | NAD | NAD(P) transhydrogenase subunit alpha | 1.6.1.2 | 0.442 | |
| 2b4t | AES | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.442 | |
| 2bxq | IMN | Serum albumin | / | 0.442 | |
| 2ch6 | ADP | N-acetyl-D-glucosamine kinase | 2.7.1.59 | 0.442 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.442 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.442 | |
| 2p83 | MR0 | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 2rio | ADP | Serine/threonine-protein kinase/endoribonuclease IRE1 | 2.7.11.1 | 0.442 | |
| 2uv0 | OHN | Transcriptional activator protein LasR | / | 0.442 | |
| 3b70 | NAP | Enoyl reductase LovC | 1 | 0.442 | |
| 3cvu | FAD | RE11660p | / | 0.442 | |
| 3fr8 | NDP | Ketol-acid reductoisomerase, chloroplastic | 1.1.1.86 | 0.442 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.442 | |
| 3iok | 1P6 | Tyrosine-protein kinase JAK2 | / | 0.442 | |
| 3jyp | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.442 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.442 | |
| 3py0 | SU9 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 3qk0 | QK0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.442 | |
| 4aw0 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.442 | |
| 4g2f | C07 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.442 | |
| 4gk2 | L66 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.442 | |
| 4mok | FAD | Pyranose 2-oxidase | / | 0.442 | |
| 4nm9 | FAD | Bifunctional protein PutA | / | 0.442 | |
| 4pd6 | URI | Nucleoside permease | / | 0.442 | |
| 4q5j | ANP | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.442 | |
| 4riy | ADP | Epidermal growth factor receptor | 2.7.10.1 | 0.442 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 1bpj | UMP | Thymidylate synthase | / | 0.441 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.441 | |
| 1jol | FFO | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.441 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.441 | |
| 1n4p | CYS_VAL_ILE_LEU_GER | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.441 | |
| 1q3e | PCG | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 | / | 0.441 | |
| 1rfv | ADP | Pyridoxal kinase | 2.7.1.35 | 0.441 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.441 | |
| 2brb | PFQ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 2cda | NAP | Glucose 1-dehydrogenase | / | 0.441 | |
| 2chx | 090 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.441 | |
| 2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.441 | |
| 2ibz | UQ6 | Cytochrome b | / | 0.441 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.441 | |
| 2v2q | NVG | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.441 | |
| 3bht | MFR | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 3e8x | NAP | BH1520 protein | / | 0.441 | |
| 3ibq | ATP | Pyridoxal kinase | / | 0.441 | |
| 3lfs | A07 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 3oet | NAD | Erythronate-4-phosphate dehydrogenase | / | 0.441 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.441 | |
| 4e4q | RRH | Peroxisome proliferator-activated receptor gamma | / | 0.441 | |
| 4fcw | ADP | Chaperone protein ClpB | / | 0.441 | |
| 4jx1 | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 4l4c | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 4l4f | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 4lcf | 1WL | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.441 | |
| 4nmc | FAD | Bifunctional protein PutA | / | 0.441 | |
| 4qmw | KS1 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.441 | |
| 4wlo | NAI | Malate dehydrogenase, mitochondrial | 1.1.1.37 | 0.441 | |
| 5dld | UD1 | UDP-N-Acetylglucosamine 2-epimerase | / | 0.441 | |
| 5e8x | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.441 | |
| 5eb5 | FAD | (R)-mandelonitrile lyase 1 | 4.1.2.10 | 0.441 | |
| 5iub | CLR | Adenosine receptor A2a | / | 0.441 | |
| 5jsf | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.441 | |
| 1b8v | NAD | Malate dehydrogenase | / | 0.440 | |
| 1gzu | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.440 | |
| 1kt3 | RTL | Retinol-binding protein 4 | / | 0.440 | |
| 1nyt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.440 | |
| 1o6q | R17 | Squalene--hopene cyclase | 4.2.1.129 | 0.440 | |
| 1p0p | BCH | Cholinesterase | 3.1.1.8 | 0.440 | |
| 1pr9 | NAP | L-xylulose reductase | 1.1.1.10 | 0.440 | |
| 1q41 | IXM | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.440 | |
| 2fn7 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.440 | |
| 2itv | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.440 | |
| 2itw | ITQ | Epidermal growth factor receptor | 2.7.10.1 | 0.440 | |
| 2p9g | NAI | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.440 | |
| 2wxv | WXV | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 2y0m | ACO | Histone acetyltransferase KAT8 | / | 0.440 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.440 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.440 | |
| 3cgd | COA | Coenzyme A disulfide reductase | / | 0.440 | |
| 3i7e | DJR | Gag-Pol polyprotein | / | 0.440 | |
| 3inv | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.440 | |
| 3lz6 | A0D | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.440 | |
| 3nj0 | PYV | Abscisic acid receptor PYL2 | / | 0.440 | |
| 3pd3 | A3T | Threonine--tRNA ligase | 6.1.1.3 | 0.440 | |
| 3q8u | ADP | Nucleoside diphosphate kinase | / | 0.440 | |
| 3rf7 | NAD | Iron-containing alcohol dehydrogenase | / | 0.440 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.440 | |
| 3wcz | NAP | Aldo-keto reductase AKR2E4 | / | 0.440 | |
| 4c9p | CAM | Cytochrome P450 | / | 0.440 | |
| 4fc7 | NAP | Peroxisomal 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.440 | |
| 4hhz | 15S | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.440 | |
| 4hjo | AQ4 | Epidermal growth factor receptor | 2.7.10.1 | 0.440 | |
| 4iqg | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.440 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.440 | |
| 5dw6 | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.440 |