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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2gcdSTUSerine/threonine-protein kinase TAO22.7.11.1

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
2gcdSTUSerine/threonine-protein kinase TAO22.7.11.11.000
4hvh19RTyrosine-protein kinase JAK32.7.10.20.577
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.575
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.556
1yvj4STTyrosine-protein kinase JAK32.7.10.20.556
4hvg19QTyrosine-protein kinase JAK32.7.10.20.552
4jia1K3Tyrosine-protein kinase JAK2/0.547
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.542
4bibIEOMitogen-activated protein kinase kinase kinase 52.7.11.250.541
4gih0X5Non-receptor tyrosine-protein kinase TYK22.7.10.20.541
2i40BLZCyclin-dependent kinase 22.7.11.220.536
4gmy0X5Tyrosine-protein kinase JAK2/0.535
4acc7YGGlycogen synthase kinase-3 beta2.7.11.260.530
4e4m0NHTyrosine-protein kinase JAK2/0.530
4qmySTUSerine/threonine-protein kinase 242.7.11.10.528
4bidIE8Mitogen-activated protein kinase kinase kinase 52.7.11.250.526
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.524
5e8wSTUTGF-beta receptor type-12.7.11.300.524
1u5rATPSerine/threonine-protein kinase TAO22.7.11.10.523
4k1b1OCSerine/threonine-protein kinase pim-12.7.11.10.523
4kikKSAInhibitor of nuclear factor kappa-B kinase subunit beta2.7.11.100.522
1e9hINRCyclin-dependent kinase 22.7.11.220.521
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.521
4hvi19STyrosine-protein kinase JAK32.7.10.20.520
3ckxSTUSerine/threonine-protein kinase 242.7.11.10.518
2cchATPCyclin-dependent kinase 22.7.11.220.517
1eh4IC1Casein kinase I homolog 12.7.11.10.515
3zewSTUEphrin type-B receptor 42.7.10.10.515
4qmtH1NSerine/threonine-protein kinase 242.7.11.10.515
1u4dDBQActivated CDC42 kinase 1/0.514
2h96893Mitogen-activated protein kinase 82.7.11.240.514
1aq1STUCyclin-dependent kinase 22.7.11.220.513
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.513
3lcdBDYMacrophage colony-stimulating factor 1 receptor2.7.10.10.513
2vtqLZACyclin-dependent kinase 22.7.11.220.512
4eok4SPCyclin-dependent kinase 22.7.11.220.512
4i22IREEpidermal growth factor receptor2.7.10.10.512
3vf9477Tyrosine-protein kinase SYK2.7.10.20.511
1okySTU3-phosphoinositide-dependent protein kinase 12.7.11.10.510
4dgo0JWCasein kinase II subunit alpha2.7.11.10.510
4erwSTUCyclin-dependent kinase 22.7.11.220.510
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.509
3tnwF18Cyclin-dependent kinase 22.7.11.220.508
4jqeANPCasein kinase II subunit alpha2.7.11.10.508
4yzcSTUSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.508
1h1r6CPCyclin-dependent kinase 22.7.11.220.506
4bgg844Activin receptor type-12.7.11.300.506
4qmxH8HSerine/threonine-protein kinase 242.7.11.10.506
2j0m4STFocal adhesion kinase 12.7.10.20.505
3js2VM1Fibroblast growth factor receptor 1/0.505
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.505
1xjdSTUProtein kinase C theta type2.7.11.130.504
2c3kABOSerine/threonine-protein kinase Chk12.7.11.10.504
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.504
2ivuZD6Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.504
2x1nX1NCyclin-dependent kinase 22.7.11.220.504
3cblSTUTyrosine-protein kinase Fes/Fps2.7.10.20.504
3cd3STUTyrosine-protein kinase Fes/Fps2.7.10.20.504
3cjgKIMVascular endothelial growth factor receptor 22.7.10.10.502
3bkbSTUTyrosine-protein kinase Fes/Fps2.7.10.20.501
3f7z34OGlycogen synthase kinase-3 beta2.7.11.260.501
3vs5VSGTyrosine-protein kinase HCK2.7.10.20.501
1pkdUCNCyclin-dependent kinase 22.7.11.220.500
1py5PY1TGF-beta receptor type-12.7.11.300.500
2iw6QQ2Cyclin-dependent kinase 22.7.11.220.500
4gii0X6Non-receptor tyrosine-protein kinase TYK22.7.10.20.500
4nj32KDCyclin-dependent kinase 22.7.11.220.500
4qmnDB8Serine/threonine-protein kinase 242.7.11.10.500
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.499
3zh8C58Protein kinase C iota type2.7.11.130.499
4k181OBSerine/threonine-protein kinase pim-12.7.11.10.499
4mf029ZTyrosine-protein kinase ITK/TSK2.7.10.20.499
2ayp43ASerine/threonine-protein kinase Chk12.7.11.10.498
2objVRVSerine/threonine-protein kinase pim-12.7.11.10.498
2wihP48Cyclin-dependent kinase 22.7.11.220.498
4k110J9Proto-oncogene tyrosine-protein kinase Src2.7.10.20.498
1nxkSTUMAP kinase-activated protein kinase 22.7.11.10.497
2rioADPSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.497
3hllI45Mitogen-activated protein kinase 14/0.497
4fyn0VETyrosine-protein kinase SYK2.7.10.20.497
1oi9N20Cyclin-dependent kinase 22.7.11.220.496
3mfsANPPeripheral plasma membrane protein CASK2.7.11.10.496
1fvv107Cyclin-dependent kinase 22.7.11.220.495
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.495
2iw94SPCyclin-dependent kinase 22.7.11.220.495
4btkDTQTau-tubulin kinase 12.7.11.10.495
4gfo0X2Non-receptor tyrosine-protein kinase TYK22.7.10.20.495
4j95ACPFibroblast growth factor receptor 2/0.495
1m2pHNACasein kinase II subunit alpha2.7.11.10.494
2c3lIDZSerine/threonine-protein kinase Chk12.7.11.10.494
3vs7KS1Tyrosine-protein kinase HCK2.7.10.20.494
4c61LMMTyrosine-protein kinase JAK2/0.494
4dgnLU2Casein kinase II subunit alpha2.7.11.10.494
1vjy460TGF-beta receptor type-12.7.11.300.493
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.493
4ckiADNProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.493
4ic7ANPMitogen-activated protein kinase 72.7.11.240.493
4nk92K5Fibroblast growth factor receptor 1/0.493
3gb2G3BGlycogen synthase kinase-3 beta2.7.11.260.492
3zep1NXTyrosine-protein kinase JAK32.7.10.20.492
1u54ACPActivated CDC42 kinase 1/0.491
2csnCKICasein kinase I homolog 12.7.11.10.491
3gxlQIGTGF-beta receptor type-12.7.11.300.491
3uyt0CKCasein kinase I isoform delta2.7.11.10.491
4g170VNCasein kinase I isoform gamma-32.7.11.10.491
2ym6YM6Serine/threonine-protein kinase Chk12.7.11.10.490
3hztJ60Calmodulin-like domain protein kinase isoform 3/0.490
3mfrANPPeripheral plasma membrane protein CASK2.7.11.10.490
4bcqTJFCyclin-dependent kinase 22.7.11.220.490
5e8xSTUTGF-beta receptor type-12.7.11.300.490
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.489
1q41IXMGlycogen synthase kinase-3 beta2.7.11.260.489
2x2lX2LProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.489
3lq5SLQCyclin-dependent kinase 92.7.11.220.489
4u9aSTUInterleukin-1 receptor-associated kinase 42.7.11.10.489
1g5sI17Cyclin-dependent kinase 22.7.11.220.488
2eufLQQCyclin-dependent kinase 62.7.11.220.488
3r2b05BMAP kinase-activated protein kinase 22.7.11.10.488
3sd0TSKGlycogen synthase kinase-3 beta2.7.11.260.488
2br1PFPSerine/threonine-protein kinase Chk12.7.11.10.487
2ghlLIBMitogen-activated protein kinase 14/0.487
3a62STURibosomal protein S6 kinase beta-12.7.11.10.487
3sheI85MAP kinase-activated protein kinase 32.7.11.10.487
4afjSJJGlycogen synthase kinase-3 beta2.7.11.260.487
1ke6LS2Cyclin-dependent kinase 22.7.11.220.486
2hy0306Serine/threonine-protein kinase Chk12.7.11.10.486
2ivvPP1Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.486
2ym44YMSerine/threonine-protein kinase Chk12.7.11.10.486
3qfvNM7Serine/threonine-protein kinase MRCK beta2.7.11.10.486
4c02TAKActivin receptor type-12.7.11.300.486
4j711JXGlycogen synthase kinase-3 beta2.7.11.260.486
4j97ACPFibroblast growth factor receptor 2/0.486
1oiuN76Cyclin-dependent kinase 22.7.11.220.485
2fb8215Serine/threonine-protein kinase B-raf2.7.11.10.485
3l8p0CEAngiopoietin-1 receptor2.7.10.10.485
4acdGR9Glycogen synthase kinase-3 beta2.7.11.260.485
4ftu7HKSerine/threonine-protein kinase Chk12.7.11.10.485
4gj20XHNon-receptor tyrosine-protein kinase TYK22.7.10.20.485
5ar4SB2Receptor-interacting serine/threonine-protein kinase 22.7.11.10.485
1h1s4SPCyclin-dependent kinase 22.7.11.220.484
2broDF2Serine/threonine-protein kinase Chk12.7.11.10.484
2wotZZGTGF-beta receptor type-12.7.11.300.484
2wouZZFTGF-beta receptor type-12.7.11.300.484
3i4bZ48Glycogen synthase kinase-3 beta2.7.11.260.484
3poz03PEpidermal growth factor receptor2.7.10.10.484
3q3b55EGlycogen synthase kinase-3 beta2.7.11.260.484
4anmWULCasein kinase II subunit alpha2.7.11.10.484
4gub0Y4Casein kinase II subunit alpha2.7.11.10.484
4o0sADNAurora kinase A2.7.11.10.484
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.483
3cqeP91Wee1-like protein kinase2.7.10.20.483
3jxwLXGSerine/threonine-protein kinase pim-12.7.11.10.483
4dit0KDGlycogen synthase kinase-3 beta2.7.11.260.483
4f630S7Fibroblast growth factor receptor 1/0.483
4nka2K7Fibroblast growth factor receptor 1/0.483
1csnATPCasein kinase I homolog 12.7.11.10.482
2b52D42Cyclin-dependent kinase 22.7.11.220.482
2pvhP19Casein kinase II subunit alpha2.7.11.10.482
2qhm7CSSerine/threonine-protein kinase Chk12.7.11.10.482
2x2kX2KProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.482
1dawANPCasein kinase II subunit alpha2.7.11.10.481
2c6tDT5Cyclin-dependent kinase 22.7.11.220.481
2in6839Wee1-like protein kinase2.7.10.20.481
3c50ADPRhodopsin kinase/0.481
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.481
1m2qMNXCasein kinase II subunit alpha2.7.11.10.480
2pwlACPFibroblast growth factor receptor 2/0.480
3rni21ZCyclin-dependent kinase 22.7.11.220.480
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.480
4achKDIGlycogen synthase kinase-3 beta2.7.11.260.480
4g160VMCasein kinase I isoform gamma-32.7.11.10.480
4lmuQUESerine/threonine-protein kinase pim-12.7.11.10.480
1xkkFMMEpidermal growth factor receptor2.7.10.10.479
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.479
2e9oA58Serine/threonine-protein kinase Chk12.7.11.10.479
3uixQ17Serine/threonine-protein kinase pim-12.7.11.10.479
3uli1N3Cyclin-dependent kinase 22.7.11.220.479
4ix6ADPUncharacterized protein/0.479
1q5kTMUGlycogen synthase kinase-3 beta2.7.11.260.478
1qcfPP1Tyrosine-protein kinase HCK2.7.10.20.478
3a99ANPSerine/threonine-protein kinase pim-12.7.11.10.478
3ezrEZRCyclin-dependent kinase 22.7.11.220.478
4fsuHK5Serine/threonine-protein kinase Chk12.7.11.10.478
1zys199Serine/threonine-protein kinase Chk12.7.11.10.477
3l1sZ92Glycogen synthase kinase-3 beta2.7.11.260.477
3w2sW2REpidermal growth factor receptor2.7.10.10.477
4wo5324Serine/threonine-protein kinase B-raf2.7.11.10.477
5d12G97Proto-oncogene tyrosine-protein kinase Src2.7.10.20.477
1fm4DXCMajor pollen allergen Bet v 1-L/0.476
1snuSTUTyrosine-protein kinase ITK/TSK2.7.10.20.476
3bhtMFRCyclin-dependent kinase 22.7.11.220.476
3lfnA27Cyclin-dependent kinase 22.7.11.220.476
4jrvKJVEpidermal growth factor receptor2.7.10.10.476
2uzdC85Cyclin-dependent kinase 22.7.11.220.475
2wmqZYQSerine/threonine-protein kinase Chk12.7.11.10.475
3w33W19Epidermal growth factor receptor2.7.10.10.475
4bdfH3RSerine/threonine-protein kinase Chk22.7.11.10.475
4dn5AGSMitogen-activated protein kinase kinase kinase 142.7.11.250.475
4im2BX7Serine/threonine-protein kinase TBK12.7.11.10.475
4y93746Tyrosine-protein kinase/0.475
5drdATPAurora kinase A2.7.11.10.475
2bikBI1Serine/threonine-protein kinase pim-12.7.11.10.474
2iw84SPCyclin-dependent kinase 22.7.11.220.474
3f69XDRSerine/threonine-protein kinase PknB2.7.11.10.474
3hmm855TGF-beta receptor type-12.7.11.300.474
3nynSGVG protein-coupled receptor kinase 62.7.11.160.474
5e8ySTUTGF-beta receptor type-22.7.11.300.474
2bdf24AProto-oncogene tyrosine-protein kinase Src2.7.10.20.473
2pvlP55Casein kinase II subunit alpha2.7.11.10.473
2py3ACPFibroblast growth factor receptor 2/0.473
2uzlC94Cyclin-dependent kinase 22.7.11.220.473
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.473
2x6dX6DAurora kinase A2.7.11.10.473
3cy2MB9Serine/threonine-protein kinase pim-12.7.11.10.473
4hbm0Y7E3 ubiquitin-protein ligase Mdm26.3.20.473
4kb81QOCasein kinase I isoform delta2.7.11.10.473
1mq4ADPAurora kinase A2.7.11.10.472
1pyePM1Cyclin-dependent kinase 22.7.11.220.472
2jedLG8Protein kinase C theta type2.7.11.130.472
3iw4LW4Protein kinase C alpha type2.7.11.130.472
3vid4TTVascular endothelial growth factor receptor 22.7.10.10.472
4ez50RSCyclin-dependent kinase 62.7.11.220.472
4f640S8Fibroblast growth factor receptor 1/0.472
4fsnA58Serine/threonine-protein kinase Chk12.7.11.10.472
4oa9ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.472
1yhsSTUSerine/threonine-protein kinase pim-12.7.11.10.471
2dwbANPAurora kinase A2.7.11.10.471
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.471
3emg685Tyrosine-protein kinase SYK2.7.10.20.471
3lfqA28Cyclin-dependent kinase 22.7.11.220.471
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.471
4nks2M2Fibroblast growth factor receptor 1/0.471
4yuqKS1Calmodulin-like domain protein kinase/0.471
5ajqDB8Serine/threonine-protein kinase 102.7.11.10.471
1lp4ANPCasein kinase II subunit alpha2.7.11.10.470
1stcSTUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.470
2c0oL2GTyrosine-protein kinase HCK2.7.10.20.470
2fvdLIACyclin-dependent kinase 22.7.11.220.470
2xngA0HAurora kinase A2.7.11.10.470
3oom507Activin receptor type-12.7.11.300.470
3vryB43Tyrosine-protein kinase HCK2.7.10.20.470
4bdgP3JSerine/threonine-protein kinase Chk22.7.11.10.470
4bieIE6Mitogen-activated protein kinase kinase kinase 52.7.11.250.470
4ftiH7KSerine/threonine-protein kinase Chk12.7.11.10.470
4gu94GUFocal adhesion kinase 12.7.10.20.470
4qmlANPSerine/threonine-protein kinase 242.7.11.10.470
1rw8580TGF-beta receptor type-12.7.11.300.469
2brgDFYSerine/threonine-protein kinase Chk12.7.11.10.469
2vu3LZECyclin-dependent kinase 22.7.11.220.469
2xj1XJ1Serine/threonine-protein kinase pim-12.7.11.10.469
3zc6VFCTyrosine-protein kinase JAK32.7.10.20.469
4enxZ20Serine/threonine-protein kinase pim-12.7.11.10.469
4hni16WCasein kinase I isoform epsilon2.7.11.10.469
4jajXU1Aurora kinase A2.7.11.10.469
4l7sG7KTyrosine-protein kinase ITK/TSK2.7.10.20.469
1gij2PUCyclin-dependent kinase 22.7.11.220.468
2c5nCK8Cyclin-dependent kinase 22.7.11.220.468
2cdz23DSerine/threonine-protein kinase PAK 42.7.11.10.468
2chlDKICasein kinase I isoform gamma-32.7.11.10.468
2gnfY27cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.468
2vttLZDCyclin-dependent kinase 22.7.11.220.468
3blrCPBCyclin-dependent kinase 92.7.11.220.468
3mvl38PMitogen-activated protein kinase 14/0.468
3uimANPBRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 12.7.10.10.468
4fx360KCyclin-dependent kinase 22.7.11.220.468
4k0y1OASerine/threonine-protein kinase pim-12.7.11.10.468
4wkqIREEpidermal growth factor receptor2.7.10.10.468
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.467
1q3dSTUGlycogen synthase kinase-3 beta2.7.11.260.467
1q8uH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.467
1q97ATPSerine/threonine-protein kinase SKY12.7.11.10.467
2bkzSBCCyclin-dependent kinase 22.7.11.220.467
2o65MYFSerine/threonine-protein kinase pim-12.7.11.10.467
2uzeC95Cyclin-dependent kinase 22.7.11.220.467
2vuw5IDSerine/threonine-protein kinase haspin2.7.11.10.467
3vs4VSFTyrosine-protein kinase HCK2.7.10.20.467
4fsmHK1Serine/threonine-protein kinase Chk12.7.11.10.467
4oacADPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.467
1uv5BRWGlycogen synthase kinase-3 beta2.7.11.260.466
1xr1ANPSerine/threonine-protein kinase pim-12.7.11.10.466
2i0ePDSProtein kinase C beta type2.7.11.130.466
2itzIREEpidermal growth factor receptor2.7.10.10.466
2z2w770Wee1-like protein kinase2.7.10.20.466
3cy3JN5Serine/threonine-protein kinase pim-12.7.11.10.466
3hx4ANPCalmodulin-domain protein kinase 1/0.466
3w32W32Epidermal growth factor receptor2.7.10.10.466
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.466
4ftn2HKSerine/threonine-protein kinase Chk12.7.11.10.466
4hgs15GCasein kinase I isoform gamma-32.7.11.10.466
4idtT28Mitogen-activated protein kinase kinase kinase 142.7.11.250.466
4iwq1FVSerine/threonine-protein kinase TBK12.7.11.10.466
4jlcSU6Serine/threonine-protein kinase TBK12.7.11.10.466
4jr3KJREpidermal growth factor receptor2.7.10.10.466
2c0iL1GTyrosine-protein kinase HCK2.7.10.20.465
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.465
2f2cAP9Cyclin-dependent kinase 62.7.11.220.465
3jy0LYGSerine/threonine-protein kinase pim-12.7.11.10.465
3mtfA3FActivin receptor type-12.7.11.300.465
3vs2VSBTyrosine-protein kinase HCK2.7.10.20.465
4b7tCWTGlycogen synthase kinase-3 beta2.7.11.260.465
4j98ACPFibroblast growth factor receptor 2/0.465
4kbk1QGCasein kinase I isoform delta2.7.11.10.465
1bygSTUTyrosine-protein kinase CSK/0.464
1y91CT9Cyclin-dependent kinase 22.7.11.220.464
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.464
2izsBRQCasein kinase I isoform gamma-32.7.11.10.464
3umxQ18Serine/threonine-protein kinase pim-12.7.11.10.464
4bbfO19Tyrosine-protein kinase JAK2/0.464
1dayGNPCasein kinase II subunit alpha2.7.11.10.463
1oecAA2Fibroblast growth factor receptor 2/0.463
3a60STURibosomal protein S6 kinase beta-12.7.11.10.463
3at4CCKCasein kinase II subunit alpha2.7.11.10.463
3cxw7CPSerine/threonine-protein kinase pim-12.7.11.10.463
3mfuANPPeripheral plasma membrane protein CASK2.7.11.10.463
4bcoT6QCyclin-dependent kinase 22.7.11.220.463
4eutBX7Serine/threonine-protein kinase TBK12.7.11.10.463
4gk3L87Ephrin type-A receptor 32.7.10.10.463
5amnDTQProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.463
5dt3ATPAurora kinase A2.7.11.10.463
2izrBRKCasein kinase I isoform gamma-32.7.11.10.462
3fz1B98Cyclin-dependent kinase 22.7.11.220.462
3vrzVRZTyrosine-protein kinase HCK2.7.10.20.462
4bgePYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.462
4fkw62KCyclin-dependent kinase 22.7.11.220.462
4g34924Eukaryotic translation initiation factor 2-alpha kinase 32.7.11.10.462
4jr7GNPCasein kinase II subunit alpha2.7.11.10.462
4o0wADNAurora kinase A2.7.11.10.462
2j2iLY4Serine/threonine-protein kinase pim-12.7.11.10.461
3bhh5CPCalcium/calmodulin-dependent protein kinase type II subunit beta2.7.11.170.461
3i60E86Mitogen-activated protein kinase 12.7.11.240.461
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.461
4fic0ULProto-oncogene tyrosine-protein kinase Src2.7.10.20.461
4fob0USALK tyrosine kinase receptor2.7.10.10.461
4gj30XPNon-receptor tyrosine-protein kinase TYK22.7.10.20.461
1j1bANPGlycogen synthase kinase-3 beta2.7.11.260.460
1oguST8Cyclin-dependent kinase 22.7.11.220.460
2uzuL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.460
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.460
3adaNADSubunit alpha of sarocosine oxidase/0.460
3oroAGSSerine/threonine protein kinase/0.460
3rkb12ZCyclin-dependent kinase 22.7.11.220.460
4bcmT7ZCyclin-dependent kinase 22.7.11.220.460
1finATPCyclin-dependent kinase 22.7.11.220.459
2ckeIQUDeath-associated protein kinase 2/0.459
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.459
2w05FRTCyclin-dependent kinase 22.7.11.220.459
3bbtFMMReceptor tyrosine-protein kinase erbB-42.7.10.10.459
3r9dX6BCyclin-dependent kinase 22.7.11.220.459
3r9hZ67Cyclin-dependent kinase 22.7.11.220.459
4cfnJYMCyclin-dependent kinase 22.7.11.220.459
4n702HXSerine/threonine-protein kinase pim-12.7.11.10.459
1m2rMNYCasein kinase II subunit alpha2.7.11.10.458
2ow3BIMGlycogen synthase kinase-3 beta2.7.11.260.458
2x8iX8ISerine/threonine-protein kinase Chk12.7.11.10.458
3sc13S13-phosphoinositide-dependent protein kinase 12.7.11.10.458
3vs0VS0Tyrosine-protein kinase HCK2.7.10.20.458
3zrlZRLGlycogen synthase kinase-3 beta2.7.11.260.458
4dgmAGICasein kinase II subunit alpha2.7.11.10.458
4fk3325Serine/threonine-protein kinase B-raf2.7.11.10.458
4fl1ANPTyrosine-protein kinase SYK2.7.10.20.458
4fv1EK4Mitogen-activated protein kinase 12.7.11.240.458
4hyi1AOSerine/threonine-protein kinase Chk12.7.11.10.458
5a4kFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.458
1ouk084Mitogen-activated protein kinase 14/0.457
1q3wATUGlycogen synthase kinase-3 beta2.7.11.260.457
2etrY27Rho-associated protein kinase 12.7.11.10.457
2ijmADPFocal adhesion kinase 12.7.10.20.457
2v7a627Tyrosine-protein kinase ABL12.7.10.20.457
2y6o1N1Ephrin type-A receptor 42.7.10.10.457
3r7uX96Cyclin-dependent kinase 22.7.11.220.457
4rrvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.457
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.457
5auwQUEDeath-associated protein kinase 12.7.11.10.457
1o6yACPSerine/threonine-protein kinase PknB2.7.11.10.456
2bheBRYCyclin-dependent kinase 22.7.11.220.456
2fumMIXSerine/threonine-protein kinase PknB2.7.11.10.456
2uzbC75Cyclin-dependent kinase 22.7.11.220.456
3ml8ML8Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.456
3s1dZIRCytokinin dehydrogenase 11.5.99.120.456
3v8t477Tyrosine-protein kinase ITK/TSK2.7.10.20.456
4dymIYZActivin receptor type-12.7.11.300.456
4f650S9Fibroblast growth factor receptor 1/0.456
4g1wG1WMitogen-activated protein kinase 82.7.11.240.456
4rqkATP3-phosphoinositide-dependent protein kinase 12.7.11.10.456
1q99ANPSerine/threonine-protein kinase SKY12.7.11.10.455
1yi3LY2Serine/threonine-protein kinase pim-12.7.11.10.455
2etkHFSRho-associated protein kinase 12.7.11.10.455
3ma301ISerine/threonine-protein kinase pim-12.7.11.10.455
4dk50KOPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.455
4fg7ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.455
4k33ACPFibroblast growth factor receptor 32.7.10.10.455
1ir3ANPInsulin receptor2.7.10.10.454
2of4979Tyrosine-protein kinase Lck2.7.10.20.454
2uzvSS5cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.454
3b8r887Vascular endothelial growth factor receptor 22.7.10.10.454
3ddqRRCCyclin-dependent kinase 22.7.11.220.454
3tkuM77Serine/threonine-protein kinase MRCK beta2.7.11.10.454
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.454
4ezk0SDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.454
4f081RSTyrosine-protein kinase JAK2/0.454
4ft9H4KSerine/threonine-protein kinase Chk12.7.11.10.454
4fv6E57Mitogen-activated protein kinase 12.7.11.240.454
4hgl0YOCasein kinase I isoform gamma-32.7.11.10.454
4iva1J5Tyrosine-protein kinase JAK2/0.454
4l521ULMitogen-activated protein kinase kinase kinase 72.7.11.250.454
1bvrNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.453
1xwsBI1Serine/threonine-protein kinase pim-12.7.11.10.453
2bhhRYUCyclin-dependent kinase 22.7.11.220.453
2c6eHPMAurora kinase A2.7.11.10.453
2j0lANPFocal adhesion kinase 12.7.10.20.453
2xyuQ9GEphrin type-A receptor 42.7.10.10.453
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.453
3s1h56ZCyclin-dependent kinase 22.7.11.220.453
3s2a2NQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.453
3vw6IM6Mitogen-activated protein kinase kinase kinase 52.7.11.250.453
4acg6LQGlycogen synthase kinase-3 beta2.7.11.260.453
4aojV4ZHigh affinity nerve growth factor receptor2.7.10.10.453
4bzo676Serine/threonine-protein kinase pim-12.7.11.10.453
4gh2HK0Serine/threonine-protein kinase Chk12.7.11.10.453
1bwsNDPGDP-L-fucose synthase/0.452
1pyxANPGlycogen synthase kinase-3 beta2.7.11.260.452
1wvxBD4Death-associated protein kinase 12.7.11.10.452
1ydtIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.452
2c0tL3GTyrosine-protein kinase HCK2.7.10.20.452
3hrfATP3-phosphoinositide-dependent protein kinase 12.7.11.10.452
3nunJMZ3-phosphoinositide-dependent protein kinase 12.7.11.10.452
4aotGW8Serine/threonine-protein kinase 102.7.11.10.452
4hnf16WCasein kinase I isoform delta2.7.11.10.452
1ol7ADPAurora kinase A2.7.11.10.451
1ykr628Cyclin-dependent kinase 22.7.11.220.451
2oh02PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.451
2qo7ANPEphrin type-A receptor 32.7.10.10.451
2vv9IM9Cyclin-dependent kinase 22.7.11.220.451
3qu0X40Cyclin-dependent kinase 22.7.11.220.451
4anuEM7Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.451
4bc6XZNSerine/threonine-protein kinase 102.7.11.10.451
4btjATPTau-tubulin kinase 12.7.11.10.451
4ct1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.451
4hyu1BKMitogen-activated protein kinase 82.7.11.240.451
4jbpYPHAurora kinase A2.7.11.10.451
4mf129YTyrosine-protein kinase ITK/TSK2.7.10.20.451
4q5jANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.451
1h1q2A6Cyclin-dependent kinase 22.7.11.220.450
2io6330Wee1-like protein kinase2.7.10.20.450
3bgqVX2Serine/threonine-protein kinase pim-12.7.11.10.450
3c0g3AMPeripheral plasma membrane protein CASK2.7.11.10.450
3kf7L9GMitogen-activated protein kinase 14/0.450
3my5RFZCyclin-dependent kinase 22.7.11.220.450
3rak03ZCyclin-dependent kinase 22.7.11.220.450
3w18N13Aurora kinase A2.7.11.10.450
4eon1ROCyclin-dependent kinase 22.7.11.220.450
5cshATPCasein kinase II subunit alpha2.7.11.10.450
1hvlA76Gag-Pol polyprotein/0.449
1jioDEB6-deoxyerythronolide B hydroxylase/0.449
1pxoCK7Cyclin-dependent kinase 22.7.11.220.449
1yi4ADNSerine/threonine-protein kinase pim-12.7.11.10.449
3at3ATKCasein kinase II subunit alpha2.7.11.10.449
3fzr3JZProtein-tyrosine kinase 2-beta2.7.10.20.449
3qaqQAQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.449
3qcq3Q03-phosphoinositide-dependent protein kinase 12.7.11.10.449
3sp9IL2Peroxisome proliferator-activated receptor delta/0.449
3tz3B36Acetyl-CoA carboxylase/0.449
3vbq0F5Serine/threonine-protein kinase pim-12.7.11.10.449
3zrmZRMGlycogen synthase kinase-3 beta2.7.11.260.449
4bznUGXSerine/threonine-protein kinase pim-12.7.11.10.449
4jq8KJ8Epidermal growth factor receptor2.7.10.10.449
4lm5Q17Serine/threonine-protein kinase pim-12.7.11.10.449
1ke7LS3Cyclin-dependent kinase 22.7.11.220.448
1x8b824Wee1-like protein kinase2.7.10.20.448
1yw2PGJMitogen-activated protein kinase 14/0.448
2j0k4STFocal adhesion kinase 12.7.10.20.448
2jdsL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.448
2pmoHMDProtein kinase 7/0.448
2vtjLZ4Cyclin-dependent kinase 22.7.11.220.448
2xvdAS6Ephrin type-B receptor 42.7.10.10.448
2zv2609Calcium/calmodulin-dependent protein kinase kinase 22.7.11.170.448
3bheBZNGag-Pol polyprotein3.4.23.160.448
3hrcATP3-phosphoinositide-dependent protein kinase 12.7.11.10.448
3qxpX64Cyclin-dependent kinase 22.7.11.220.448
3rvg17PTyrosine-protein kinase JAK2/0.448
4eufNADTrans-2-enoyl-CoA reductase [NADH]/0.448
4ezj0SCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.448
4fz60VGTyrosine-protein kinase SYK2.7.10.20.448
4ogrADNCyclin-dependent kinase 92.7.11.220.448
5auxKMPDeath-associated protein kinase 12.7.11.10.448
2btsU32Cyclin-dependent kinase 22.7.11.220.447
2f7e2EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.447
2hk51BMTyrosine-protein kinase HCK2.7.10.20.447
2uw0GVKcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.447
3ac5KZMTyrosine-protein kinase Lck2.7.10.20.447
3apfBMWPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
3biz61EWee1-like protein kinase2.7.10.20.447
3cr0809Wee1-like protein kinase2.7.10.20.447
3kkvB99cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.447
3nr4PYVAbscisic acid receptor PYL2/0.447
3nszANPCasein kinase II subunit alpha2.7.11.10.447
3nwxKVSGag-Pol polyprotein3.4.23.160.447
3oibFDAPutative acyl-CoA dehydrogenase/0.447
3prfFP3Serine/threonine-protein kinase B-raf2.7.11.10.447
3qk0QK0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
3qtzX42Cyclin-dependent kinase 22.7.11.220.447
3zrkZRKGlycogen synthase kinase-3 beta2.7.11.260.447
4anwO92Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
4aqc88ATyrosine-protein kinase JAK2/0.447
4enyJ19Serine/threonine-protein kinase pim-12.7.11.10.447
4hle17VPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
2oapANPType II secretion system protein (GspE-2)/0.446
2of2547Tyrosine-protein kinase Lck2.7.10.20.446
3ac1KZITyrosine-protein kinase Lck2.7.10.20.446
3i81EBIInsulin-like growth factor 1 receptor2.7.10.10.446
3lltANPProtein serine/threonine kinase-1/0.446
3r7iX9ICyclin-dependent kinase 22.7.11.220.446
4bfmANPMaternal embryonic leucine zipper kinase2.7.11.10.446
4cd0AWJALK tyrosine kinase receptor2.7.10.10.446
4fjyFJYPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
4ftq4HKSerine/threonine-protein kinase Chk12.7.11.10.446
4hge15VTyrosine-protein kinase JAK2/0.446
4nm0ADPGlycogen synthase kinase-3 beta2.7.11.260.446
4q72FADBifunctional protein PutA/0.446
4wsqKSAAP2-associated protein kinase 12.7.11.10.446
5auuLU2Death-associated protein kinase 12.7.11.10.446
5dr6SKEAurora kinase A2.7.11.10.446
1r0eDFNGlycogen synthase kinase-3 beta2.7.11.260.445
2cgu3A3Serine/threonine-protein kinase Chk12.7.11.10.445
2ds11CDCyclin-dependent kinase 22.7.11.220.445
2e9p77ASerine/threonine-protein kinase Chk12.7.11.10.445
2e9v85ASerine/threonine-protein kinase Chk12.7.11.10.445
2itnANPEpidermal growth factor receptor2.7.10.10.445
2itpAEEEpidermal growth factor receptor2.7.10.10.445
2ittAEEEpidermal growth factor receptor2.7.10.10.445
2jkoBIJFocal adhesion kinase 12.7.10.20.445
3bgpVX1Serine/threonine-protein kinase pim-12.7.11.10.445
3hl7I47Mitogen-activated protein kinase 14/0.445
3nux3NVCyclin-dependent kinase 62.7.11.220.445
3qlg1N1Proto-oncogene tyrosine-protein kinase Src2.7.10.20.445
3w2rW2REpidermal growth factor receptor2.7.10.10.445
4a06ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.445
4fkv61KCyclin-dependent kinase 22.7.11.220.445
4jboWPHAurora kinase A2.7.11.10.445
4o0rX4ZSerine/threonine-protein kinase PAK 12.7.11.10.445
4yryFADGlutamate synthase, beta subunit/0.445
1m17AQ4Epidermal growth factor receptor2.7.10.10.444
2b9iADPMitogen-activated protein kinase FUS32.7.11.240.444
2etm7PYFocal adhesion kinase 12.7.10.20.444
3c4zADPRhodopsin kinase/0.444
3d7tSTUTyrosine-protein kinase CSK/0.444
3ofm4B0Casein kinase II subunit alpha'2.7.11.10.444
3rpv26ZCyclin-dependent kinase 22.7.11.220.444
4fkt48KCyclin-dependent kinase 22.7.11.220.444
4i0s1B5Tyrosine-protein kinase SYK2.7.10.20.444
4mxxDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.444
5c8wPCGcGMP-dependent protein kinase 22.7.11.120.444
1rx8FOLDihydrofolate reductase1.5.1.30.443
2p33J07Mitogen-activated protein kinase 102.7.11.240.443
2uxoTACHTH-type transcriptional regulator TtgR/0.443
3dogNNNCyclin-dependent kinase 22.7.11.220.443
3l9lL9LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.443
3ncgBK1Calmodulin-domain protein kinase 1, putative/0.443
3ttiKBIMitogen-activated protein kinase 102.7.11.240.443
3vf80JETyrosine-protein kinase SYK2.7.10.20.443
3vs6VSHTyrosine-protein kinase HCK2.7.10.20.443
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.443
4tyj0LIFibroblast growth factor receptor 42.7.10.10.443
1om1IQACasein kinase II subunit alpha2.7.11.10.442
2f4bEHAPeroxisome proliferator-activated receptor gamma/0.442
2vf0F89Thymidylate synthase/0.442
3dgaNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.442
3el51UNGag-Pol polyprotein/0.442
3f883HTGlycogen synthase kinase-3 beta2.7.11.260.442
3krwBA1Beta-adrenergic receptor kinase 12.7.11.150.442
3qd03Q43-phosphoinositide-dependent protein kinase 12.7.11.10.442
3rk708ZCyclin-dependent kinase 22.7.11.220.442
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.442
3v5j0F2Tyrosine-protein kinase ITK/TSK2.7.10.20.442
4dfn0K1Tyrosine-protein kinase SYK2.7.10.20.442
4flh14KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
4hyh1AMSerine/threonine-protein kinase Chk12.7.11.10.442
4i0r1B4Tyrosine-protein kinase SYK2.7.10.20.442
4krcAGSCyclin-dependent protein kinase PHO852.7.11.220.442
4qmzB49Serine/threonine-protein kinase 242.7.11.10.442
5dnrATPAurora kinase A2.7.11.10.442
1difA85Gag-Pol polyprotein/0.441
1rfuADPPyridoxal kinase2.7.1.350.441
2a7r5GPGMP reductase 2/0.441
2w17I19Cyclin-dependent kinase 22.7.11.220.441
3qzhX69Cyclin-dependent kinase 22.7.11.220.441
4feq0T8Tyrosine-protein kinase receptor TYRO32.7.10.10.441
4ivb1J5Tyrosine-protein kinase JAK1/0.441
4jq7KJQEpidermal growth factor receptor2.7.10.10.441
4mq22C4Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.441
4uyaAGSMitogen-activated protein kinase kinase kinase 212.7.11.250.441
5cnoANPEpidermal growth factor receptor2.7.10.10.441
5dr9SKEAurora kinase A2.7.11.10.441
1f4eTPRThymidylate synthase/0.440
1fwkADPHomoserine kinase2.7.1.390.440
1ivp1ZKGag-Pol polyprotein/0.440
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.440
1xl2189Gag-Pol polyprotein3.4.23.160.440
2brbPFQSerine/threonine-protein kinase Chk12.7.11.10.440
2wmsZYSSerine/threonine-protein kinase Chk12.7.11.10.440
2yitYITSerine/threonine-protein kinase Chk22.7.11.10.440
3ambVX6cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.440
3pjcPJCTyrosine-protein kinase JAK32.7.10.20.440
3qd33Q53-phosphoinositide-dependent protein kinase 12.7.11.10.440
3qtrX36Cyclin-dependent kinase 22.7.11.220.440
4e730NRMitogen-activated protein kinase 82.7.11.240.440
4e93GUITyrosine-protein kinase Fes/Fps2.7.10.20.440
4ftlH0KSerine/threonine-protein kinase Chk12.7.11.10.440
4hvb19PPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
4kz01UJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
4n6z2HWSerine/threonine-protein kinase pim-12.7.11.10.440