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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2bd0BIOSepiapterin reductase

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity
Align
2bd0BIOSepiapterin reductase/1.000
2a58RBF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.538
2vz0D64Pteridine reductase/0.524
4stdBFSScytalone dehydratase4.2.1.940.504
4xczT3QQdtf/0.501
3stdMQ0Scytalone dehydratase4.2.1.940.499
2xujTZ5Acetylcholinesterase3.1.1.70.498
3rgzBLDProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.497
2xuoTZ4Acetylcholinesterase3.1.1.70.493
4a959MTGlycylpeptide N-tetradecanoyltransferase/0.493
4dbw511Aldo-keto reductase family 1 member C3/0.492
1kyvRBF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.488
1xngDNDNH(3)-dependent NAD(+) synthetase6.3.1.50.488
2f98NGVAklanonic acid methyl ester cyclase AcmA5.5.1.230.488
3wqmB29Diterpene synthase3.1.7.80.488
1isgAGSADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 23.2.2.60.487
4b117I1Glycylpeptide N-tetradecanoyltransferase/0.487
4cb629RPolymerase basic protein 2/0.487
4nceMGTPolymerase basic protein 2/0.487
5cc9DDFDihydrofolate reductase1.5.1.30.487
2iu8UD1UDP-3-O-acylglucosamine N-acyltransferase2.3.10.486
3pkeY10Methionine aminopeptidase 2/0.486
4lm4JPZcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.486
4yfy0FXVioF/0.485
4ajfF03cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.484
2xuqTZ4Acetylcholinesterase3.1.1.70.483
1u08PLPMethionine aminotransferase/0.482
4b12C23Glycylpeptide N-tetradecanoyltransferase/0.482
4a33PS8Glycylpeptide N-tetradecanoyltransferase/0.481
1ejbINJ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.479
1i5rHYCEstradiol 17-beta-dehydrogenase 11.1.1.620.479
3u57DH8Raucaffricine-O-beta-D-glucosidase3.2.1.1250.479
4eplJAIJasmonic acid-amido synthetase JAR16.3.20.479
1z8962PAldose reductase1.1.1.210.478
3exfTPPPyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial1.2.4.10.478
3exfTPPPyruvate dehydrogenase E1 component subunit beta, mitochondrial1.2.4.10.478
4ajdF04cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.478
1mlzPLPAdenosylmethionine-8-amino-7-oxononanoate aminotransferase2.6.1.620.477
1ni4TPPPyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial1.2.4.10.477
1ni4TPPPyruvate dehydrogenase E1 component subunit beta, mitochondrial1.2.4.10.477
1zisINI6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.477
2cekN8TAcetylcholinesterase3.1.1.70.477
3f3y4OABile salt sulfotransferase2.8.2.140.477
3p2vDOYAldose reductase1.1.1.210.477
3sl8JN7cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.477
4jpg1OXPyruvate kinase PKM2.7.1.400.477
2nvcITAAldose reductase1.1.1.210.476
1pj7FFODimethylglycine oxidase1.5.3.100.475
3r8hZOMAldo-keto reductase family 1 member C3/0.475
4b144XBGlycylpeptide N-tetradecanoyltransferase/0.475
4pnmNU1Tankyrase-22.4.2.300.475
1kmsLIHDihydrofolate reductase1.5.1.30.474
1thnADPAnti-sigma F factor/0.474
3nubUD0UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase2.6.1.980.474
3zj6VM2Raucaffricine-O-beta-D-glucosidase3.2.1.1250.474
4kq6DLZ6,7-dimethyl-8-ribityllumazine synthase/0.474
3fsjD7KBenzoylformate decarboxylase4.1.1.70.473
3hxdBD7Geranylgeranyl transferase type-2 subunit beta2.5.1.600.473
4cb741GPolymerase basic protein 2/0.473
1rxjBNIStreptavidin/0.472
2c1zU2FAnthocyanidin 3-O-glucosyltransferase 22.4.1.1150.472
2hvoZSTAldose reductase1.1.1.210.472
1rzuADPGlycogen synthase 12.4.1.210.471
3dr4G4MGDP-perosamine synthase/0.471
5a4wQCTGlutathione S-transferase F22.5.1.180.471
2vqzMGTPolymerase basic protein 2/0.470
3lzzGDPUncharacterized protein/0.470
3ugrIMNAldo-keto reductase family 1 member C3/0.470
4kbn25UDihydrofolate reductase1.5.1.30.470
1ry0PG2Aldo-keto reductase family 1 member C3/0.469
3gx9TXDMorphinone reductase/0.469
3iktNADRedox-sensing transcriptional repressor Rex/0.469
4bftZVTPantothenate kinase2.7.1.330.469
5fmmMGTPolymerase basic protein 2/0.469
1efyBZCPoly [ADP-ribose] polymerase 12.4.2.300.468
1ut6A8NAcetylcholinesterase3.1.1.70.468
3g1rNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.468
3zc3FADFerredoxin--NADP reductase1.18.1.20.468
4b13X25Glycylpeptide N-tetradecanoyltransferase/0.468
4g090VDHistidinol dehydrogenase/0.468
4i101BSBeta-secretase 13.4.23.460.468
2a59LMZ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.467
3bxoUPPdTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose/0.467
4drjRAPSerine/threonine-protein kinase mTOR2.7.11.10.467
4drjRAPPeptidyl-prolyl cis-trans isomerase FKBP45.2.1.80.467
4imoPWZProstaglandin-H2 D-isomerase5.3.99.20.467
1nqvLMZ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.466
2c1zKMPAnthocyanidin 3-O-glucosyltransferase 22.4.1.1150.466
3h3qH13Collagen type IV alpha-3-binding protein/0.466
3zv7NHGAcetylcholinesterase3.1.1.70.466
4bbhYBNGlycylpeptide N-tetradecanoyltransferase/0.466
1s7gNADNAD-dependent protein deacylase 2/0.465
1y2bDEEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.465
2pdj393Aldose reductase1.1.1.210.465
3dr7GPDGDP-perosamine synthase/0.465
3e4aQIXInsulin-degrading enzyme3.4.24.560.465
4hcy0YNTransketolase/0.465
1uk1FRQPoly [ADP-ribose] polymerase 12.4.2.300.464
2cbqTH2Neocarzinostatin/0.464
2x9vTMQPteridine reductase/0.464
3sni546cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.464
4kn104JFolate receptor beta/0.464
1a26CNAPoly [ADP-ribose] polymerase 12.4.2.300.463
2vrjNCWBeta-glucosidase A3.2.1.210.463
2w6cBM4Acetylcholinesterase3.1.1.70.463
3lboLDTAldose reductase1.1.1.210.463
4kdrSAHUbiquinone biosynthesis O-methyltransferase/0.463
5cxv0HKMuscarinic acetylcholine receptor M1/0.463
4u163C0Muscarinic acetylcholine receptor M3/0.463
1fwyUD1Bifunctional protein GlmU/0.462
1qgyFADFerredoxin--NADP reductase1.18.1.20.462
1z3n3NAAldose reductase1.1.1.210.462
2fjm073Tyrosine-protein phosphatase non-receptor type 13.1.3.480.462
2ipiAKYAclacinomycin-N/aclacinomycin-A oxidase/0.462
2pb1NFGGlucan 1,3-beta-glucosidase/0.462
3af4GCPPantothenate kinase2.7.1.330.462
3aivHBO4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase, chloroplastic3.2.1.1820.462
3r8gIZPAldo-keto reductase family 1 member C3/0.462
3u5ySCGRaucaffricine-O-beta-D-glucosidase3.2.1.1250.462
5a4vQUEGlutathione S-transferase F22.5.1.180.462
1e6zNGOChitinase/0.461
1rftPXMPyridoxal kinase2.7.1.350.461
1s07PLPAdenosylmethionine-8-amino-7-oxononanoate aminotransferase2.6.1.620.461
1yw8A75Methionine aminopeptidase 2/0.461
2a57CRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.461
2gg2U12Methionine aminopeptidase/0.461
2pdxZSTAldose reductase1.1.1.210.461
2wsa646Glycylpeptide N-tetradecanoyltransferase/0.461
2xuiTZ5Acetylcholinesterase3.1.1.70.461
4hmn16JAldo-keto reductase family 1 member C3/0.461
4zqcF6FTryptophan synthase alpha chain/0.461
1o2g696Prothrombin3.4.21.50.460
1queFADFerredoxin--NADP reductase1.18.1.20.460
1ro98BRcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.460
1v3q2DIPurine nucleoside phosphorylase2.4.2.10.460
1xonPILcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.460
2aot2PMHistamine N-methyltransferase2.1.1.80.460
2ovvPFHcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.460
3p0fBAUUridine phosphorylase 22.4.2.30.460
3tfuPL8Adenosylmethionine-8-amino-7-oxononanoate aminotransferase2.6.1.620.460
4cb4MGTPolymerase basic protein 2/0.460
4kmzFOLFolate receptor beta/0.460
4lcw1VYMajor histocompatibility complex class I-related gene protein/0.460
4n9qFMNFMN-dependent NADH-azoreductase 1/0.460
5fd8A5APutative carboxypeptidase yocD/0.460
1w6jR71Lanosterol synthase5.4.99.70.459
1w87FADFerredoxin--NADP reductase1.18.1.20.459
2bfmTOPPteridine reductase 11.5.1.330.459
2e8uIPEGeranylgeranyl pyrophosphate synthase/0.459
2hxzH7JCathepsin S3.4.22.270.459
2jgbMGTEukaryotic translation initiation factor 4E type 2/0.459
3e4vFMNUncharacterized protein/0.459
3irhDTPHD domain protein/0.459
3ld5LDTAldose reductase1.1.1.210.459
3ug8IMNAldo-keto reductase family 1 member C3/0.459
4dbs0HVAldo-keto reductase family 1 member C3/0.459
4fam0SZAldo-keto reductase family 1 member C3/0.459
4gv08MEPoly [ADP-ribose] polymerase 32.4.2.300.459
4hhz15SPoly [ADP-ribose] polymerase 12.4.2.300.459
4llkMEWcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.459
4phlPILPhosphodiesterase/0.459
2o6hINI6,7-dimethyl-8-ribityllumazine synthase 12.5.1.780.458
2xi4AFTAcetylcholinesterase3.1.1.70.458
3m4h388Aldose reductase1.1.1.210.458
3vf60H6Glucokinase2.7.1.20.458
1akcPPEAspartate aminotransferase, mitochondrial2.6.1.10.457
1fdsESTEstradiol 17-beta-dehydrogenase 11.1.1.620.457
1h60STRPentaerythritol tetranitrate reductase/0.457
1q0zAKAAclacinomycin methylesterase RdmC3.1.1.950.457
2iqdLPAAldose reductase1.1.1.210.457
2pdmZSTAldose reductase1.1.1.210.457
3znrNU9Histone deacetylase 73.5.1.980.457
4jt81NRNAD-dependent protein deacetylase sirtuin-3, mitochondrial3.5.10.457
4yu153NAldose reductase1.1.1.210.457
1g63FMNEpidermin decarboxylase4.1.10.456
1mrqSTRAldo-keto reductase family 1 member C1/0.456
1n5vNOMActVA 6 protein/0.456
1ry8RUTAldo-keto reductase family 1 member C3/0.456
1y60H4M5,6,7,8-tetrahydromethanopterin hydro-lyase4.2.1.1470.456
1zknIBMcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.456
2cv2GSUGlutamate--tRNA ligase6.1.1.170.456
2gbyBRNHTH-type transcriptional regulator QacR/0.456
3cmfPDN3-oxo-5-beta-steroid 4-dehydrogenase/0.456
3cuiX4SExoglucanase/xylanase3.2.1.910.456
3gf4U5PUDP-galactopyranose mutase5.4.99.90.456
3h4vDVPPteridine reductase 11.5.1.330.456
3hxcBD6Geranylgeranyl transferase type-2 subunit beta2.5.1.600.456
3pkbY16Methionine aminopeptidase 2/0.456
3qpoPFRcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.456
3r43ID8Aldo-keto reductase family 1 member C3/0.456
3rj0BLDProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.456
3szfDCQSulfide-quinone reductase/0.456
4da50H7Choline kinase alpha2.7.1.320.456
4s1iPLPPyridoxal kinase, putative/0.456
1d3dBZTProthrombin3.4.21.50.455
1ib0FADNADH-cytochrome b5 reductase 31.6.2.20.455
1y2c3DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.455
1zz1SHHHistone deacetylase-like amidohydrolase3.5.10.455
2g7yMO9Cathepsin S3.4.22.270.455
2ouyCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.455
2psjCEIRenilla-luciferin 2-monooxygenase1.13.12.50.455
3biz61EWee1-like protein kinase2.7.10.20.455
3nu03TUDihydrofolate reductase1.5.1.30.455
3qkzNAPAldose reductase-related protein 11.1.1.210.455
3uzzTES3-oxo-5-beta-steroid 4-dehydrogenase/0.455
4ajm3A6cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.455
4fa30SLAldo-keto reductase family 1 member C3/0.455
4g1nNZTPyruvate kinase PKM2.7.1.400.455
4gm4TZDBenzoylformate decarboxylase4.1.1.70.455
1akaPLPAspartate aminotransferase, mitochondrial2.6.1.10.454
1el3I84Aldose reductase1.1.1.210.454
1gj5130Prothrombin3.4.21.50.454
1kyxCRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.454
1nsgRADPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.454
1nsgRADSerine/threonine-protein kinase mTOR2.7.11.10.454
1wsvTHHAminomethyltransferase, mitochondrial/0.454
2gg3U13Methionine aminopeptidase/0.454
2pdfZSTAldose reductase1.1.1.210.454
2zevIPEGeranylgeranyl pyrophosphate synthase/0.454
3h3t16HCollagen type IV alpha-3-binding protein/0.454
3iakEV1cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.454
3uzzASD3-oxo-5-beta-steroid 4-dehydrogenase/0.454
1dgbNDPCatalase1.11.1.60.453
1lnmDTXBilin-binding protein/0.453
1y2d4DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.453
2iki388Aldose reductase1.1.1.210.453
2is72CLAldose reductase1.1.1.210.453
2o8h227cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.453
3c1oNAPEugenol synthase/0.453
3dopNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.453
3k31NADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.453
3nxyD2HDihydrofolate reductase1.5.1.30.453
3r7mSUZAldo-keto reductase family 1 member C3/0.453
3uzxAOM3-oxo-5-beta-steroid 4-dehydrogenase/0.453
4dz5NAPAldo-keto reductase family 1 member C3/0.453
4l1xNAPAldo-keto reductase family 1 member C2/0.453
4li61XOTankyrase-12.4.2.300.453
1paxDHQPoly [ADP-ribose] polymerase 12.4.2.300.452
1s36CEIObelin/0.452
1t41ID5Aldose reductase1.1.1.210.452
2ejzSAHDiphthine synthase/0.452
2f3815MAldo-keto reductase family 1 member C3/0.452
2fapRADPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.452
2fapRADSerine/threonine-protein kinase mTOR2.7.11.10.452
3buvNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.452
3cgtBCDCyclomaltodextrin glucanotransferase2.4.1.190.452
3hiiPNTAmiloride-sensitive amine oxidase [copper-containing]/0.452
3k4s0MOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.452
3ntqNADInositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase1.1.1.180.452
4ey6GNTAcetylcholinesterase3.1.1.70.452
4itxIN5Cystathionine beta-lyase MetC4.4.1.80.452
4mrm2BYGamma-aminobutyric acid type B receptor subunit 1/0.452
4zzjCNANAD-dependent protein deacetylase sirtuin-13.5.10.452
6stdMS2Scytalone dehydratase4.2.1.940.452
1tkcM6TTransketolase 12.2.1.10.451
1uhjCZBAequorin-2/0.451
2bfaCB3Pteridine reductase 11.5.1.330.451
2pdn47DAldose reductase1.1.1.210.451
3cv6HXSAldo-keto reductase family 1 member C21/0.451
3pkaY02Methionine aminopeptidase 2/0.451
3uzxAOX3-oxo-5-beta-steroid 4-dehydrogenase/0.451
4m0f1YKAcetylcholinesterase3.1.1.70.451
4nv14TGFormyl transferase/0.451
1ekoI84Aldose reductase1.1.1.210.450
1uhhCZPAequorin-2/0.450
1vp5NAPOxidoreductase, aldo/keto reductase family/0.450
1xnzFCDMethionine aminopeptidase/0.450
1zgbA1EAcetylcholinesterase3.1.1.70.450
2c0cNAPProstaglandin reductase 310.450
2i16LDTAldose reductase1.1.1.210.450
2ikj393Aldose reductase1.1.1.210.450
2xupTZ5Acetylcholinesterase3.1.1.70.450
3gjwGJWPoly [ADP-ribose] polymerase 12.4.2.300.450
3hl0NADMaleylacetate reductase/0.450
3lz5LDTAldose reductase1.1.1.210.450
3r6iJMSAldo-keto reductase family 1 member C3/0.450
4araC56Acetylcholinesterase3.1.1.70.450
4fl0PLPAminotransferase ALD1, chloroplastic2.6.10.450
4ms1381Gamma-aminobutyric acid type B receptor subunit 1/0.450
1gpnHUBAcetylcholinesterase3.1.1.70.449
1pwlBFIAldose reductase1.1.1.210.449
1uwhBAXSerine/threonine-protein kinase B-raf2.7.11.10.449
1w4lGL8Acetylcholinesterase3.1.1.70.449
1x8lOXRRetinol dehydratase/0.449
1z4iUMP5'(3')-deoxyribonucleotidase, mitochondrial3.1.30.449
2hv5ZSTAldose reductase1.1.1.210.449
2pdwFIDAldose reductase1.1.1.210.449
3gyf51PDihydrofolate reductase1.5.1.30.449
3ituIBMcGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.449
3rtnRTNBeta-secretase 13.4.23.460.449
3zo7K6HMuconolactone Delta-isomerase/0.449
4arbC57Acetylcholinesterase3.1.1.70.449
4bvhOCZNAD-dependent protein deacetylase sirtuin-3, mitochondrial3.5.10.449
4bvhAR6NAD-dependent protein deacetylase sirtuin-3, mitochondrial3.5.10.449
4fllYZ6Methionine aminopeptidase 1/0.449
4jq4IMNAldo-keto reductase family 1 member C2/0.449
4s1hADPPyridoxal kinase, putative/0.449
1dlrMXADihydrofolate reductase1.5.1.30.448
1u2rSO1Elongation factor 2/0.448
1xf0ASDAldo-keto reductase family 1 member C3/0.448
1yc2NADNAD-dependent protein deacylase 2/0.448
1ygjRMCPyridoxal kinase2.7.1.350.448
1zuaTOLAldo-keto reductase family 1 member B101.1.10.448
2fzjDH3Dihydrofolate reductase1.5.1.30.448
2g5w8PG12-oxophytodienoate reductase 31.3.1.420.448
2pdbZSTAldose reductase1.1.1.210.448
2pdu393Aldose reductase1.1.1.210.448
2rc6FADFerredoxin--NADP reductase/0.448
2uuk897Prothrombin3.4.21.50.448
2v2zCDM4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.448
2xegCI9Glutamate carboxypeptidase 23.4.17.210.448
3r9fGSUMccE protein/0.448
4a2zVIQGlycylpeptide N-tetradecanoyltransferase/0.448
4ddl0JQcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.448
4mm48PRNa(+):neurotransmitter symporter (Snf family)/0.448
1d3pBT3Prothrombin3.4.21.50.447
1t40ID5Aldose reductase1.1.1.210.447
1u65CP0Acetylcholinesterase3.1.1.70.447
1wm1PTBProline iminopeptidase3.4.11.50.447
2agtFIDAldose reductase1.1.1.210.447
2aouCQAHistamine N-methyltransferase2.1.1.80.447
2bxqIMNSerum albumin/0.447
2clfF6FTryptophan synthase alpha chain/0.447
2gg0U11Methionine aminopeptidase/0.447
2rd2QSIGlutamine--tRNA ligase6.1.1.180.447
2x1hX1HProstaglandin reductase 310.447
3c49KU8Poly [ADP-ribose] polymerase 32.4.2.300.447
3pkdY10Methionine aminopeptidase 2/0.447
3q9bB3NAcetylpolyamine amidohydrolase/0.447
4cb593GPolymerase basic protein 2/0.447
4dbuBT9Aldo-keto reductase family 1 member C3/0.447
4gts7TPGeranylgeranyl transferase type-2 subunit beta2.5.1.600.447
4to4DCPDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.447
1xq04TRCarbonic anhydrase 24.2.1.10.446
1y2k7DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.446
1zgcA2EAcetylcholinesterase3.1.1.70.446
2qjpANJCytochrome b/0.446
3byzH11Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.446
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.446
3g1rFIT3-oxo-5-beta-steroid 4-dehydrogenase/0.446
3ghvGHCDihydrofolate reductase1.5.1.30.446
3mjrAC2Deoxycytidine kinase2.7.1.740.446
3nn6HNK6-hydroxy-L-nicotine oxidase/0.446
3wd9QPCcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.446
3zovWZVBeta-secretase 13.4.23.460.446
4a7zAY9Aldos-2-ulose dehydratase/0.446
4bfsZVSPantothenate kinase2.7.1.330.446
4hrqAZGCytidine and deoxycytidylate deaminase zinc-binding region/0.446
4j7gTRHPCZA361.3/0.446
4m6kFOLDihydrofolate reductase1.5.1.30.446
5dp2NAPCurF/0.446
1us0LDTAldose reductase1.1.1.210.445
1x8b824Wee1-like protein kinase2.7.10.20.445
1xzqFONtRNA modification GTPase MnmE3.6.50.445
2ay3MPPAromatic-amino-acid aminotransferase2.6.1.570.445
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.445
3ghtLDTAldose reductase1.1.1.210.445
3k47D09Dihydrofolate reductase1.5.1.30.445
3lenZSTAldose reductase1.1.1.210.445
4aoaIK2Beta-phenylalanine transaminase2.6.10.445
4b66FADL-ornithine N(5)-monooxygenase/0.445
4bekXK0Beta-secretase 13.4.23.460.445
4e32DWNMethyltransferase/0.445
4kn2LYAFolate receptor beta/0.445
4xo7ASDAldo-keto reductase family 1 member C2/0.445
5stdUNNScytalone dehydratase4.2.1.940.445
1b2rFADFerredoxin--NADP reductase1.18.1.20.444
1gjrFADFerredoxin--NADP reductase1.18.1.20.444
1gky5GPGuanylate kinase2.7.4.80.444
1ihiIU5Aldo-keto reductase family 1 member C2/0.444
1p0pBCHCholinesterase3.1.1.80.444
1pqc444Oxysterols receptor LXR-beta/0.444
1x2eATXProline iminopeptidase3.4.11.50.444
1zklIBMHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A3.1.4.530.444
2ha6SCKAcetylcholinesterase3.1.1.70.444
2i17LDTAldose reductase1.1.1.210.444
2pdlTOLAldose reductase1.1.1.210.444
2xuhTZ4Acetylcholinesterase3.1.1.70.444
3f8sPF2Dipeptidyl peptidase 4/0.444
3g4iD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.444
3gcq1BUMitogen-activated protein kinase 14/0.444
3i9jNFDADP-ribosyl cyclase/cyclic ADP-ribose hydrolase3.2.2.60.444
3p9tTCLRepressor/0.444
3v35NTIAldose reductase1.1.1.210.444
3w5uFADFerredoxin/0.444
4fcb0T7cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.444
4gabFIDAldo-keto reductase family 1 member B101.1.10.444
4hld16TThymidylate kinase/0.444
4kfjFOLDihydrofolate reductase1.5.1.30.444
4lsaBLDProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.444
4tnzTTPDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.444
1bx0FADFerredoxin--NADP reductase, chloroplastic1.18.1.20.443
1dghNDPCatalase1.11.1.60.443
1e1fPSG4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1, chloroplastic3.2.1.1820.443
1eveE20Acetylcholinesterase3.1.1.70.443
1nquRDL6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.443
1odcA8BAcetylcholinesterase3.1.1.70.443
1rpwDIDHTH-type transcriptional regulator QacR/0.443
1sm4FADFerredoxin--NADP reductase/0.443
1toiHCIAspartate aminotransferase2.6.1.10.443
1x2bSTXProline iminopeptidase3.4.11.50.443
1y2e5DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.443
2d06ESTSulfotransferase 1A12.8.2.10.443
2dv0ZSTAldose reductase1.1.1.210.443
2qxwLDTAldose reductase1.1.1.210.443
2rkuR78Serine/threonine-protein kinase PLK12.7.11.210.443
3af1GDPPantothenate kinase2.7.1.330.443
3burTES3-oxo-5-beta-steroid 4-dehydrogenase/0.443
3dlaNXXGlutamine-dependent NAD(+) synthetase6.3.5.10.443
3h3r14HCollagen type IV alpha-3-binding protein/0.443
3nxvD2FDihydrofolate reductase1.5.1.30.443
3zj0ACOPutative acetyltransferase OgpAT/0.443
4flkY10Methionine aminopeptidase 1/0.443
4gr9372Ribosyldihydronicotinamide dehydrogenase [quinone]/0.443
4j7hTRHPCZA361.3/0.443
4x9dU5PUncharacterized protein MJ1435/0.443
1jf0CZHObelin/0.442
1o6qR17Squalene--hopene cyclase4.2.1.1290.442
1ohjCOPDihydrofolate reductase1.5.1.30.442
1s1pNAPAldo-keto reductase family 1 member C3/0.442
1tfz8694-hydroxyphenylpyruvate dioxygenase1.13.11.270.442
2f59INI6,7-dimethyl-8-ribityllumazine synthase 1/0.442
2gyuHI6Acetylcholinesterase3.1.1.70.442
2hzqSTRApolipoprotein D/0.442
2ouu35GcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.442
2qx7NAPEugenol synthase 11.1.1.3180.442
2xugTZ4Acetylcholinesterase3.1.1.70.442
3af0GDPPantothenate kinase2.7.1.330.442
3d3p20AcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.442
3dylIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.442
3fvuIACKynurenine--oxoglutarate transaminase 12.6.1.70.442
3gf4UPGUDP-galactopyranose mutase5.4.99.90.442
3iu7FCDMethionine aminopeptidase 2/0.442
3iu9T07Methionine aminopeptidase 2/0.442
3jq8DX3Pteridine reductase, putative/0.442
3l3rOAGDihydrofolate reductase1.5.1.30.442
3n3zIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.442
3sxjSAMPutative methyltransferase/0.442
3zj7C1KStrictosidine-O-beta-D-glucosidase3.2.1.1050.442
4b68NAPL-ornithine N(5)-monooxygenase/0.442
4jsr1NQNAD-dependent protein deacetylase sirtuin-3, mitochondrial3.5.10.442
4pahLNRPhenylalanine-4-hydroxylase1.14.16.10.442
3ny9JSZBeta-2 adrenergic receptor/0.442
1pj6FOLDimethylglycine oxidase1.5.3.100.441
1po7TZDBenzoylformate decarboxylase4.1.1.70.441
1pr4MTPPurine nucleoside phosphorylase DeoD-type/0.441
1qinGIPLactoylglutathione lyase4.4.1.50.441
1r58AO5Methionine aminopeptidase 2/0.441
1yplRA8Prothrombin3.4.21.50.441
2j3qTFLAcetylcholinesterase3.1.1.70.441
2mjiKTRFatty acid-binding protein, intestinal/0.441
2weaPP6Penicillopepsin-13.4.23.200.441
2zseACPPantothenate kinase2.7.1.330.441
3br3ETHTH-type transcriptional regulator QacR/0.441
3elePLPAminotransferase/0.441
3exhTPPPyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial1.2.4.10.441
3exhTPPPyruvate dehydrogenase E1 component subunit beta, mitochondrial1.2.4.10.441
3hbfMYCFlavonoid 3-O-glucosyltransferase2.4.10.441
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.441
3l3lL3LPoly [ADP-ribose] polymerase 12.4.2.300.441
3wb50B4Beta-secretase 13.4.23.460.441
4fal0T0Aldo-keto reductase family 1 member C3/0.441
4kp61S1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.441
5liu388Aldo-keto reductase family 1 member B101.1.10.441
4u140HKMuscarinic acetylcholine receptor M3/0.441
1ah0SBIAldose reductase1.1.1.210.440
1fmlRTLRetinol dehydratase/0.440
1j8qFMNFlavodoxin/0.440
1mapKETAspartate aminotransferase, mitochondrial2.6.1.10.440
1votHUPAcetylcholinesterase3.1.1.70.440
1z71L17Prothrombin3.4.21.50.440
2aotSAHHistamine N-methyltransferase2.1.1.80.440
2bf7HBIPteridine reductase 11.5.1.330.440
2io6330Wee1-like protein kinase2.7.10.20.440
2nmtMIMGlycylpeptide N-tetradecanoyltransferase2.3.1.970.440
2pdc393Aldose reductase1.1.1.210.440
2uuoLK3UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.440
2vqjTFGHistone deacetylase 43.5.1.980.440
2y60M8FIsopenicillin N synthase1.21.3.10.440
3c1kT15Prothrombin3.4.21.50.440
3g5iDNBPyrimidine-specific ribonucleoside hydrolase RihA/0.440
3ghuLDTAldose reductase1.1.1.210.440
3nxtD2EDihydrofolate reductase1.5.1.30.440
4cax646Glycylpeptide N-tetradecanoyltransferase2.3.1.970.440
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.440
4hyf1AKTankyrase-22.4.2.300.440
4kfqKFQGlutamate receptor ionotropic, NMDA 1/0.440
5d7qAR6NAD-dependent protein deacetylase sirtuin-23.5.10.440