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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1y6rMTM5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase3.2.2.9

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity
Align
1y6rMTM5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase3.2.2.91.000
1zosMTM5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase/0.620
3eeiMTM5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase/0.615
1y6qTDI5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase3.2.2.90.613
3dp9BIG5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase/0.607
4x24TDI5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase/0.580
1nc1MTH5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase3.2.2.90.569
4bmzMTAAminodeoxyfutalosine nucleosidase/0.563
4wkbTDI5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase/0.556
1y2bDEEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.496
3o73O73Ribosyldihydronicotinamide dehydrogenase [quinone]/0.495
1xorZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.494
1nbmADPATP synthase subunit beta, mitochondrial3.6.3.140.493
1y2e5DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.492
1o6qR17Squalene--hopene cyclase4.2.1.1290.489
1y2d4DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.489
3o56ZG1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.489
5agyGTBTau class glutathione S-transferase/0.489
3rl45GPMetallophosphoesterase MPPED23.10.488
1fdsESTEstradiol 17-beta-dehydrogenase 11.1.1.620.486
1h35R01Squalene--hopene cyclase4.2.1.1290.486
2ouyCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.485
3bsyACOUDP-N-acetylbacillosamine N-acetyltransferase2.3.1.2030.485
4kak06UDihydrofolate reductase1.5.1.30.485
2weyEV1cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.484
3qp8HL0Transcriptional activator, LuxR/UhpA family of regulators/0.483
4fr10V2Queuine tRNA-ribosyltransferase2.4.2.290.483
3k4s0MOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.482
3nxyD2HDihydrofolate reductase1.5.1.30.481
3ox1695Ribosyldihydronicotinamide dehydrogenase [quinone]/0.481
1ro6ROLcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.480
2ouu35GcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.480
3tl1JROPutative polyketide cyclase/0.478
1blzACVIsopenicillin N synthase1.21.3.10.477
2y6fM9FIsopenicillin N synthase1.21.3.10.477
3c72CX1Geranylgeranyl transferase type-2 subunit beta2.5.1.600.477
2jc6QPPCalcium/calmodulin-dependent protein kinase type 1D2.7.11.170.476
2x20PIDPeridinin-chlorophyll a-binding protein 1, chloroplastic/0.476
3g4gD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.476
3ns2PYVAbscisic acid receptor PYL2/0.476
1jomFFODihydrofolate reductase1.5.1.30.475
4hshQEIQueuine tRNA-ribosyltransferase2.4.2.290.475
4lm4JPZcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.475
1u1cBAUUridine phosphorylase2.4.2.30.474
4zvmDM2Ribosyldihydronicotinamide dehydrogenase [quinone]/0.474
1y2k7DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.473
2cbqTH2Neocarzinostatin/0.473
3hxeBD8Geranylgeranyl transferase type-2 subunit beta2.5.1.600.473
3tkyN7I(Iso)eugenol O-methyltransferase2.1.1.1460.473
4hf415HcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.473
3lq2TDPPyruvate dehydrogenase E1 component1.2.4.10.472
4eh8IRGMitogen-activated protein kinase 14/0.472
1q63AIQQueuine tRNA-ribosyltransferase2.4.2.290.471
2qmzLDPRibosyldihydronicotinamide dehydrogenase [quinone]/0.471
2wo7ASVIsopenicillin N synthase1.21.3.10.471
3d3p20AcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.470
3dhcCYKN-acyl homoserine lactonase AiiA3.1.1.810.470
3gc4AAQQueuine tRNA-ribosyltransferase2.4.2.290.470
4az0S61Lysosomal protective protein3.4.16.50.470
4gh10WXQueuine tRNA-ribosyltransferase2.4.2.290.470
4ixc1JDGlucokinase2.7.1.20.470
4n1gCEIObelin/0.470
1hfqMOTDihydrofolate reductase1.5.1.30.469
1ohjCOPDihydrofolate reductase1.5.1.30.469
1sg0STLRibosyldihydronicotinamide dehydrogenase [quinone]/0.469
1zklIBMHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A3.1.4.530.469
3ug8IMNAldo-keto reductase family 1 member C3/0.469
4a959MTGlycylpeptide N-tetradecanoyltransferase/0.469
4fcb0T7cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.469
1hfrMOTDihydrofolate reductase1.5.1.30.468
1nquRDL6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.468
3hxcBD6Geranylgeranyl transferase type-2 subunit beta2.5.1.600.468
3nxrD2DDihydrofolate reductase1.5.1.30.468
4iwv1J9Glucokinase2.7.1.20.468
1rxjBNIStreptavidin/0.467
1sojIBMcGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.467
3acy702Dehydrosqualene synthase/0.467
3nhlYTRRibosyldihydronicotinamide dehydrogenase [quinone]/0.467
4ddl0JQcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.467
1kdmDHTSex hormone-binding globulin/0.466
1txtCAAHMG-CoA synthase/0.466
2bt4CA23-dehydroquinate dehydratase4.2.1.100.466
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.466
2z1xPRFQueuine tRNA-ribosyltransferase2.4.2.290.466
3o57ZG2cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.466
3reoEUG(Iso)eugenol O-methyltransferase2.1.1.1460.466
4llkMEWcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.466
1e26GPBDihydrofolate reductase1.5.1.30.465
1lhuESTSex hormone-binding globulin/0.465
2ivpATPtRNA N6-adenosine threonylcarbamoyltransferase/0.465
2potGUNQueuine tRNA-ribosyltransferase2.4.2.290.465
2y0jAXCcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.465
3ojgHL4Phosphotriesterase/0.465
3p0fBAUUridine phosphorylase 22.4.2.30.465
3pg3DG7Mitogen-activated protein kinase 14/0.465
3qp6HL6Transcriptional activator, LuxR/UhpA family of regulators/0.465
4l8vNAPInositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase1.1.1.180.465
4psbGA3Cytokinin-specific binding protein/0.465
5a4wQCTGlutathione S-transferase F22.5.1.180.465
1axwMTXThymidylate synthase/0.464
1ozqPRFQueuine tRNA-ribosyltransferase2.4.2.290.464
1ro98BRcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.464
2c92TP66,7-dimethyl-8-ribityllumazine synthase2.5.1.780.464
3dzl3OCPhenazine biosynthesis protein A/B/0.464
3eanFADThioredoxin reductase 1, cytoplasmic1.8.1.90.464
3ox34X4Ribosyldihydronicotinamide dehydrogenase [quinone]/0.464
2poqISDTrans-1,2-dihydrobenzene-1,2-diol dehydrogenase1.3.1.200.463
3gytDL4Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.463
3hxdBD7Geranylgeranyl transferase type-2 subunit beta2.5.1.600.463
3iakEV1cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.463
3juoAJDPhenazine biosynthesis protein A/B/0.463
3l0lHC3Nuclear receptor ROR-gamma/0.463
3p9tTCLRepressor/0.463
1dr5NAPDihydrofolate reductase1.5.1.30.462
1s3uTQDDihydrofolate reductase1.5.1.30.462
2c94TSF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.462
2cy2ACOProbable acetyltransferase/0.462
2fzjDH3Dihydrofolate reductase1.5.1.30.462
2gzl2AA2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase4.6.1.120.462
2hzqSTRApolipoprotein D/0.462
1ndyFR3Adenosine deaminase3.5.4.40.461
1xomCIOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.461
2o1xTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.461
2w3bNDPDihydrofolate reductase1.5.1.30.461
3l3rOAGDihydrofolate reductase1.5.1.30.461
3s41S41Glucokinase2.7.1.20.461
4ajdF04cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.461
4ckrDI1Epithelial discoidin domain-containing receptor 12.7.10.10.461
4gi40EXQueuine tRNA-ribosyltransferase2.4.2.290.461
4knzCB3Thymidylate synthase/0.461
5cmx0G6Prothrombin3.4.21.50.461
3qakUKAAdenosine receptor A2a/0.461
1bk0ACVIsopenicillin N synthase1.21.3.10.460
1drfFOLDihydrofolate reductase1.5.1.30.460
2ovvPFHcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.460
2vcmM11Isopenicillin N synthase1.21.3.10.460
3vf60H6Glucokinase2.7.1.20.460
3zoiM2WIsopenicillin N synthase1.21.3.10.460
4kd79DRDihydrofolate reductase1.5.1.30.460
4qohSTLRibosyldihydronicotinamide dehydrogenase [quinone]/0.460
4yddMD1DMSO reductase family type II enzyme, molybdopterin subunit/0.460
1ib0FADNADH-cytochrome b5 reductase 31.6.2.20.459
1mrqSTRAldo-keto reductase family 1 member C1/0.459
1n71COAAac(6')-Ii protein/0.459
1u1d181Uridine phosphorylase2.4.2.30.459
3gyf51PDihydrofolate reductase1.5.1.30.459
3ituIBMcGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.459
3njoPYVAbscisic acid receptor PYR1/0.459
4phlPILPhosphodiesterase/0.459
1y60H4M5,6,7,8-tetrahydromethanopterin hydro-lyase4.2.1.1470.458
2bbqPFGThymidylate synthase/0.458
2x21PIDPeridinin-chlorophyll a-binding protein 1, chloroplastic/0.458
3hbfMYCFlavonoid 3-O-glucosyltransferase2.4.10.458
3k47D09Dihydrofolate reductase1.5.1.30.458
3qwc98PProthrombin3.4.21.50.458
3up0D7SaceDAF-12/0.458
4ajm3A6cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.458
4s1hADPPyridoxal kinase, putative/0.458
5cc9DDFDihydrofolate reductase1.5.1.30.458
1s36CEIObelin/0.457
2vbpVB1Isopenicillin N synthase1.21.3.10.457
3eon341Glutaryl-CoA dehydrogenase/0.457
3n0yAPCAdenylate cyclase 2/0.457
4dhyS41Glucokinase2.7.1.20.457
4muw2F4cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.457
4nbl2J6Caspase-63.4.22.590.457
1s3wTQTDihydrofolate reductase1.5.1.30.456
1uwhBAXSerine/threonine-protein kinase B-raf2.7.11.10.456
3nu03TUDihydrofolate reductase1.5.1.30.456
3nx2FERFerulic acid decarboxylase/0.456
3uxhUXHRibosyldihydronicotinamide dehydrogenase [quinone]/0.456
4at4T6EBDNF/NT-3 growth factors receptor2.7.10.10.456
4fhf0TTSpore photoproduct lyase/0.456
1n2vBDIQueuine tRNA-ribosyltransferase2.4.2.290.455
1vhnFMNtRNA-dihydrouridine synthase/0.455
1yw7A41Methionine aminopeptidase 2/0.455
2rdn1PL1-deoxypentalenic acid 11-beta-hydroxylase1.14.11.350.455
2uzaHTLPyruvate synthase/0.455
4gtt7TQGeranylgeranyl transferase type-2 subunit beta2.5.1.600.455
4iw8KN3Estrogen receptor/0.455
1jdzFMBPurine nucleoside phosphorylase/0.454
1ohkCOPDihydrofolate reductase1.5.1.30.454
1uaeUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.454
1w06W05Isopenicillin N synthase1.21.3.10.454
2hxzH7JCathepsin S3.4.22.270.454
3exfTPPPyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial1.2.4.10.454
3exfTPPPyruvate dehydrogenase E1 component subunit beta, mitochondrial1.2.4.10.454
3gmd2M3Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.454
3oafOAGDihydrofolate reductase1.5.1.30.454
3qpnPFKcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.454
4af7FADFerredoxin--NADP reductase, leaf isozyme, chloroplastic1.18.1.20.454
4cjx9L9C-1-tetrahydrofolate synthase, cytoplasmic, putative/0.454
4gcxPRFQueuine tRNA-ribosyltransferase2.4.2.290.454
4hmhF94Tankyrase-22.4.2.300.454
5k2aZMAAdenosine receptor A2a/0.454
1gt5BZQOdorant-binding protein/0.453
1j3jCP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.453
1mlzPLPAdenosylmethionine-8-amino-7-oxononanoate aminotransferase2.6.1.620.453
1nqvLMZ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.453
1oc1ASVIsopenicillin N synthase1.21.3.10.453
1uhlMEIRetinoic acid receptor RXR-beta/0.453
1zq5E04Aldo-keto reductase family 1 member C3/0.453
2uxxFAJLysine-specific histone demethylase 1A10.453
2yatEEUEstrogen receptor/0.453
3eigMTXDihydrofolate reductase1.5.1.30.453
3g4iD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.453
3n87N873-dehydroquinate dehydratase4.2.1.100.453
3nwb659Catechol O-methyltransferase2.1.1.60.453
3s7a684Dihydrofolate reductase1.5.1.30.453
4lzwTHMUridine phosphorylase/0.453
4y1bNAPAntE/0.453
1ejiTHFSerine hydroxymethyltransferase, cytosolic/0.452
1jtqLY3Thymidylate synthase/0.452
1kceCB3Thymidylate synthase/0.452
1q4wDQUQueuine tRNA-ribosyltransferase2.4.2.290.452
1sqbAZOCytochrome b/0.452
1wxyFRKAdenosine deaminase3.5.4.40.452
2z7gEH9Adenosine deaminase3.5.4.40.452
3prfFP3Serine/threonine-protein kinase B-raf2.7.11.10.452
3thrC2FGlycine N-methyltransferase2.1.1.200.452
4g2yNI5cGMP-specific 3',5'-cyclic phosphodiesterase/0.452
5hwqCAAHydroxymethylglutaryl-CoA synthase/0.452
5kf8ACOPredicted acetyltransferase/0.452
1jujLYAThymidylate synthase2.1.1.450.451
1kmvLIIDihydrofolate reductase1.5.1.30.451
1o6rR19Squalene--hopene cyclase4.2.1.1290.451
1pd8CO4Dihydrofolate reductase1.5.1.30.451
2hm9TRRDihydrofolate reductase1.5.1.30.451
3djlFADPutative acyl-CoA dehydrogenase AidB1.3.990.451
3gf4UPGUDP-galactopyranose mutase5.4.99.90.451
3tvxPNXcAMP-specific 3',5'-cyclic phosphodiesterase 4A3.1.4.530.451
4g95OAGDihydrofolate reductase1.5.1.30.451
4pztSOPHistone acetyltransferase p300/0.451
4q8pCKRQueuine tRNA-ribosyltransferase2.4.2.290.451
1dr4HBIDihydrofolate reductase1.5.1.30.450
1pd9CO4Dihydrofolate reductase1.5.1.30.450
1y2c3DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.450
1y5xE89Queuine tRNA-ribosyltransferase2.4.2.290.450
2bf7HBIPteridine reductase 11.5.1.330.450
2c3oTPPPyruvate synthase/0.450
2p8uCOAHydroxymethylglutaryl-CoA synthase, cytoplasmic2.3.3.100.450
2vi5Y196,7-dimethyl-8-ribityllumazine synthase2.5.1.780.450
3ppkFNISerine/threonine-protein kinase B-raf2.7.11.10.450
3pqbVGPPutative oxidoreductase/0.450
3sni546cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.450
4b4w9L9Bifunctional protein FolD/0.450
4fsa0V3Queuine tRNA-ribosyltransferase2.4.2.290.450
4tzt468Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.450
1dr3TAPDihydrofolate reductase1.5.1.30.449
1ej3CZHAequorin-2/0.449
1qiqACCIsopenicillin N synthase1.21.3.10.449
1z5uCMPClass B acid phosphatase/0.449
2d2gDZZPhosphotriesterase/0.449
2vxkCOAGlucosamine 6-phosphate acetyltransferase, putative/0.449
3burTES3-oxo-5-beta-steroid 4-dehydrogenase/0.449
3byzH11Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.449
3ge7AFQQueuine tRNA-ribosyltransferase2.4.2.290.449
3hxbBD5Geranylgeranyl transferase type-2 subunit beta2.5.1.600.449
3jyoNADQuinate/shikimate dehydrogenase (NAD(+))/0.449
3nhjA2ZRibosyldihydronicotinamide dehydrogenase [quinone]/0.449
3nytULPUDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase2.6.1.980.449
3zrbOR8Progesterone receptor/0.449
4ajfF03cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.449
4dm6TTBRetinoic acid receptor beta/0.449
4gi2NAPCrotonyl-CoA carboxylase/reductase/0.449
4y0kNAPAntE/0.449
1jtuLYBThymidylate synthase/0.448
1y5wNEZQueuine tRNA-ribosyltransferase2.4.2.290.448
2a59LMZ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.448
2vbdV10Isopenicillin N synthase1.21.3.10.448
3chr4BSLeukotriene A-4 hydrolase3.3.2.60.448
3k3iI46Mitogen-activated protein kinase 14/0.448
3nhpHGZRibosyldihydronicotinamide dehydrogenase [quinone]/0.448
3nxtD2EDihydrofolate reductase1.5.1.30.448
4dvi2IWTankyrase-12.4.2.300.448
4fevPP1Aminoglycoside 3'-phosphotransferase AphA1-IAB/0.448
4hqvQEIQueuine tRNA-ribosyltransferase2.4.2.290.448
4hutATPCob(I)yrinic acid a,c-diamide adenosyltransferase2.5.1.170.448
4kebFOLDihydrofolate reductase1.5.1.30.448
1jf2CZHObelin/0.447
1ltzHBIPhenylalanine-4-hydroxylase1.14.16.10.447
1ndzFR5Adenosine deaminase3.5.4.40.447
1rr6IMHPurine nucleoside phosphorylase2.4.2.10.447
1ygjRMCPyridoxal kinase2.7.1.350.447
2c97JCL6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.447
2fm0M98cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.447
2h3wHC5Carnitine O-acetyltransferase2.3.1.70.447
2jl1NAPTriphenylmethane reductase/0.447
3c3eGDP2-phospho-L-lactate transferase/0.447
3cgtBCDCyclomaltodextrin glucanotransferase2.4.1.190.447
3czr3CZCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.447
3hf6LX0Tryptophan 5-hydroxylase 11.14.16.40.447
4b4vL34Bifunctional protein FolD/0.447
4eh5IRGMitogen-activated protein kinase 14/0.447
4fqsLYAThymidylate synthase ThyA/0.447
4l091URTankyrase-22.4.2.300.447
4zthGG5Mitogen-activated protein kinase 14/0.447
1disBDMDihydrofolate reductase1.5.1.30.446
1diuBDMDihydrofolate reductase1.5.1.30.446
1hb1OCVIsopenicillin N synthase1.21.3.10.446
1mvtDTMDihydrofolate reductase1.5.1.30.446
1p0ySAHRibulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic2.1.1.1270.446
1rvvINI6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.446
1synF89Thymidylate synthase/0.446
1tkaN3TTransketolase 12.2.1.10.446
1zisINI6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.446
2ji9ADPOxalyl-CoA decarboxylase4.1.1.80.446
2rl52RLVascular endothelial growth factor receptor 22.7.10.10.446
3ggs2FDPurine nucleoside phosphorylase2.4.2.10.446
3qppPFWcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.446
3uxe465Ribosyldihydronicotinamide dehydrogenase [quinone]/0.446
4fam0SZAldo-keto reductase family 1 member C3/0.446
4j3lAJ5Tankyrase-22.4.2.300.446
4jqh1MFAlr2278 protein/0.446
4pl9ADPEthylene receptor 1/0.446
5g53NECAdenosine receptor A2a/0.446
1cg6MTAS-methyl-5'-thioadenosine phosphorylase/0.445
1dlrMXADihydrofolate reductase1.5.1.30.445
1gky5GPGuanylate kinase2.7.4.80.445
1mvsDTMDihydrofolate reductase1.5.1.30.445
1pj7FFODimethylglycine oxidase1.5.3.100.445
2iviACWIsopenicillin N synthase1.21.3.10.445
2v58LZJBiotin carboxylase6.3.4.140.445
3hmvHBTcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.445
3lfcZ86Mitogen-activated protein kinase 14/0.445
3s3vTOPDihydrofolate reductase1.5.1.30.445
3v0n4GWHisto-blood group ABO system transferase/0.445
3vt7VDXVitamin D3 receptor/0.445
4af3VX6Aurora kinase B2.7.11.10.445
4az3S35Lysosomal protective protein3.4.16.50.445
4b13X25Glycylpeptide N-tetradecanoyltransferase/0.445
4bbxLKFcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.445
4ddrMMVDihydrofolate reductase1.5.1.30.445
4fhd0TTSpore photoproduct lyase/0.445
4mvh2F5cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.445
4rh10TTSpore photoproduct lyase/0.445
1cd2FOLDihydrofolate reductase1.5.1.30.444
1efyBZCPoly [ADP-ribose] polymerase 12.4.2.300.444
1gj5130Prothrombin3.4.21.50.444
1hb3SCVIsopenicillin N synthase1.21.3.10.444
1nqxRLP6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.444
1qsnCOAHAT A1/0.444
1uhoVDNcGMP-specific 3',5'-cyclic phosphodiesterase/0.444
2ejuSAHtRNA (guanine(26)-N(2))-dimethyltransferase/0.444
3jsxCC2NAD(P)H dehydrogenase [quinone] 11.6.5.20.444
3wd9QPCcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.444
3zkyWT4Isopenicillin N synthase1.21.3.10.444
4a0sCO8Octenoyl-CoA reductase/carboxylase/0.444
4i6h1C8Serine/threonine-protein kinase PLK22.7.11.210.444
4li61XOTankyrase-12.4.2.300.444
4ubtCOASteroid 3-ketoacyl-CoA thiolase/0.444
4x7wMVIMycinamicin III 3''-O-methyltransferase2.1.1.2370.444
1w83L11Mitogen-activated protein kinase 14/0.443
1xonPILcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.443
1zknIBMcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.443
2c3p1TPPyruvate synthase/0.443
2clfF6FTryptophan synthase alpha chain/0.443
2g8nF83Phenylethanolamine N-methyltransferase2.1.1.280.443
3aiqHBO4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1b, chloroplastic3.2.1.1820.443
3ntz3TZDihydrofolate reductase1.5.1.30.443
3q6kSRO43.2 kDa salivary protein/0.443
3vi5M4MHematopoietic prostaglandin D synthase/0.443
4fk3325Serine/threonine-protein kinase B-raf2.7.11.10.443
4gts7TPGeranylgeranyl transferase type-2 subunit beta2.5.1.600.443
4i9z5BAcGMP-specific 3',5'-cyclic phosphodiesterase/0.443
4pnmNU1Tankyrase-22.4.2.300.443
1k4hAPQQueuine tRNA-ribosyltransferase2.4.2.290.442
1u1gBBBUridine phosphorylase2.4.2.30.442
2a9z26AAdenosine kinase2.7.1.200.442
2on6IMHPurine nucleoside phosphorylase2.4.2.10.442
2rc6FADFerredoxin--NADP reductase/0.442
2xb8XNW3-dehydroquinate dehydratase4.2.1.100.442
3hz142CHeat shock protein HSP 90-alpha/0.442
3nhuM42Ribosyldihydronicotinamide dehydrogenase [quinone]/0.442
3seqNXXGlutamine-dependent NAD(+) synthetase6.3.5.10.442
3sl6JN8cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.442
3w5eNVWcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.442
4b12C23Glycylpeptide N-tetradecanoyltransferase/0.442
4dsbA8SAbscisic acid receptor PYL3/0.442
4g1nNZTPyruvate kinase PKM2.7.1.400.442
4hdrDMDNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase/0.442
4hdrDMDArsB/0.442
4y6nUPGGlucosyl-3-phosphoglycerate synthase2.4.1.2660.442
1e1qADPATP synthase subunit beta, mitochondrial3.6.3.140.441
1fcx184Retinoic acid receptor gamma/0.441
1fdtESTEstradiol 17-beta-dehydrogenase 11.1.1.620.441
1h36R88Squalene--hopene cyclase4.2.1.1290.441
1nceCB3Thymidylate synthase/0.441
1ni4TPPPyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial1.2.4.10.441
1ni4TPPPyruvate dehydrogenase E1 component subunit beta, mitochondrial1.2.4.10.441
1p33MTXPteridine reductase 11.5.1.330.441
1rd4L08Integrin alpha-L/0.441
1s9dAFBCytohesin-2/0.441
1s9dAFBADP-ribosylation factor 1/0.441
2a57CRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.441
2azzTCHPhospholipase A2, major isoenzyme3.1.1.40.441
2c42TPPPyruvate synthase/0.441
2flhZEACytokinin-specific binding protein/0.441
2fmn4HF5,10-methylenetetrahydrofolate reductase1.5.1.200.441
2ourCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.441
2zevB71Geranylgeranyl pyrophosphate synthase/0.441
3b5iSAHIndole-3-acetate O-methyltransferase 1/0.441
3bi6396Wee1-like protein kinase2.7.10.20.441
3exhTPPPyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial1.2.4.10.441
3exhTPPPyruvate dehydrogenase E1 component subunit beta, mitochondrial1.2.4.10.441
3fhxPLPPyridoxal kinase2.7.1.350.441
3fktSIIBeta-secretase 13.4.23.460.441
3iej599Cathepsin S3.4.22.270.441
3sfxJANUncharacterized protein/0.441
3up3XCAaceDAF-12/0.441
3vruYS3Vitamin D3 receptor/0.441
4fgcPQ0NADPH-dependent 7-cyano-7-deazaguanine reductase1.7.1.130.441
4h7zGUNQueuine tRNA-ribosyltransferase2.4.2.290.441
4ia1BIVVitamin D3 receptor A/0.441
4iae1DXAlr2278 protein/0.441
4nbiD3YD-tyrosyl-tRNA(Tyr) deacylase/0.441
4yklGMPAprataxin-like protein30.441
5ai5BSUBifunctional epoxide hydrolase 23.1.3.760.441
5d7q4I5NAD-dependent protein deacetylase sirtuin-23.5.10.441
3emlZMAAdenosine receptor A2a/0.441
1fvpFMANon-fluorescent flavoprotein/0.440
1jlaTNKGag-Pol polyprotein2.7.7.490.440
1kyxCRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.440
1nqmBTNStreptavidin/0.440
1s3vTQDDihydrofolate reductase1.5.1.30.440
1t0iFMNNAD(P)H-dependent FMN reductase LOT6/0.440
1tgv5UDUridine phosphorylase2.4.2.30.440
1udtVIAcGMP-specific 3',5'-cyclic phosphodiesterase/0.440
1v7aFRCAdenosine deaminase3.5.4.40.440
1xi2CB1Ribosyldihydronicotinamide dehydrogenase [quinone]/0.440
1ybgTAVUDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.440
2b3vACODiamine acetyltransferase 1/0.440
2bu9HFVIsopenicillin N synthase1.21.3.10.440
2f99AKVAklanonic acid methyl ester cyclase AcmA5.5.1.230.440
2fr0NDP6-deoxyerythronolide-B synthase EryA1, modules 1 and 2/0.440
2lzg13QE3 ubiquitin-protein ligase Mdm26.3.20.440
2o6hINI6,7-dimethyl-8-ribityllumazine synthase 12.5.1.780.440
2x9vTMQPteridine reductase/0.440
2zi63D1Deoxycytidine kinase2.7.1.740.440
2zs9ADPPantothenate kinase2.7.1.330.440
3c35KAIGlutamate receptor ionotropic, kainate 1/0.440
3geyP34Poly [ADP-ribose] polymerase 152.4.2.300.440
3gieACPSensor histidine kinase DesK2.7.13.30.440
3jsuKA5Bifunctional dihydrofolate reductase-thymidylate synthase/0.440
3kqjUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.440
3nhyA7BRibosyldihydronicotinamide dehydrogenase [quinone]/0.440
3occDIHPurine nucleoside phosphorylase DeoD-type/0.440
3q2jCKIAminoglycoside 3'-phosphotransferase2.7.1.950.440
4j521J3Serine/threonine-protein kinase PLK12.7.11.210.440
4twnB96Ephrin type-A receptor 32.7.10.10.440
5hwrCOAHydroxymethylglutaryl-CoA synthase/0.440