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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1ifuFMCRicin3.2.2.22

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity
Align
1ifuFMCRicin3.2.2.221.000
4lwxMU2Ribosome inactivating protein/0.600
1ahbFMPRibosome-inactivating protein momordin I3.2.2.220.561
3qjiMGPRibosome inactivating protein/0.555
4emrMGPRibosome inactivating protein/0.552
5dsg0HKMuscarinic acetylcholine receptor M4/0.543
5cxv0HKMuscarinic acetylcholine receptor M1/0.540
3uweVJJAldo-keto reductase family 1 member C3/0.506
1lpcCMPAntiviral protein DAP-303.2.2.220.505
4stdBFSScytalone dehydratase4.2.1.940.501
4daj0HKMuscarinic acetylcholine receptor M3/0.501
4psbGA3Cytokinin-specific binding protein/0.497
3zc3FADFerredoxin--NADP reductase1.18.1.20.496
4u163C0Muscarinic acetylcholine receptor M3/0.494
1a26CNAPoly [ADP-ribose] polymerase 12.4.2.300.492
3u8fFGMRibosome inactivating protein/0.492
1aquESTEstrogen sulfotransferase, testis isoform2.8.2.40.491
2hxzH7JCathepsin S3.4.22.270.489
2wgs1AZGlutamine synthetase6.3.1.20.488
4pnmNU1Tankyrase-22.4.2.300.488
1dgfNDPCatalase1.11.1.60.485
3mz9BHNNickel-binding periplasmic protein/0.485
3c0zSHHHistone deacetylase 73.5.1.980.484
4jtpASCRibosome inactivating protein/0.484
3hivTXNrRNA N-glycosidase/0.483
1zydATPeIF-2-alpha kinase GCN2/0.482
3nxtD2EDihydrofolate reductase1.5.1.30.482
1gt5BZQOdorant-binding protein/0.480
1t13INI6,7-dimethyl-8-ribityllumazine synthase 2/0.478
1w29TS16,7-dimethyl-8-ribityllumazine synthase2.5.1.780.478
3c1oNAPEugenol synthase/0.478
3d73NBBPheromone-binding protein ASP1/0.478
4dbw511Aldo-keto reductase family 1 member C3/0.478
4jq3ZOMAldo-keto reductase family 1 member C2/0.478
1w19T4P6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.477
4iktTFVMethionine aminopeptidase 1/0.477
4jbxSK7Thymidine kinase/0.477
1lnmDTXBilin-binding protein/0.476
1ohkCOPDihydrofolate reductase1.5.1.30.476
2cekN8TAcetylcholinesterase3.1.1.70.476
2qw8NAPEugenol synthase 11.1.1.3180.476
4bfxZVXPantothenate kinase2.7.1.330.476
3b8xG4MPutative pyridoxamine 5-phosphate-dependent dehydrase/0.475
4i9z5BAcGMP-specific 3',5'-cyclic phosphodiesterase/0.475
1cznFMNFlavodoxin/0.474
3c10TSNHistone deacetylase 73.5.1.980.474
3nwlNDPCatalase1.11.1.60.474
3szfDCQSulfide-quinone reductase/0.474
4li61XOTankyrase-12.4.2.300.474
1kyvRBF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.473
1nj6A5AProline--tRNA ligase/0.473
1ry0PG2Aldo-keto reductase family 1 member C3/0.473
2bu9HFVIsopenicillin N synthase1.21.3.10.473
3hfbML4Tryptophan 5-hydroxylase 11.14.16.40.472
2hzqSTRApolipoprotein D/0.471
1obnASVIsopenicillin N synthase1.21.3.10.470
2vi5Y196,7-dimethyl-8-ribityllumazine synthase2.5.1.780.470
2xf3J01Uncharacterized protein/0.470
3ar4TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.470
3uzzTES3-oxo-5-beta-steroid 4-dehydrogenase/0.470
2fzjDH3Dihydrofolate reductase1.5.1.30.469
2yneYNEGlycylpeptide N-tetradecanoyltransferase/0.469
4jvmXDIEstrogen sulfotransferase2.8.2.40.469
4tjy3GNTankyrase-22.4.2.300.469
5cc9DDFDihydrofolate reductase1.5.1.30.469
2qxxTTPdCTP deaminase3.5.4.130.468
2xnmWGZSerine/threonine-protein kinase Nek22.7.11.10.468
3fsjD7KBenzoylformate decarboxylase4.1.1.70.468
4f79P53Putative phospho-beta-glucosidase/0.468
3hggCHDCmeR/0.467
1dggNDPCatalase1.11.1.60.466
1n5vNOMActVA 6 protein/0.466
1t40ID5Aldose reductase1.1.1.210.466
2c9dPHR6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.466
3b8hNADExotoxin A2.4.2.360.466
3ce0P34Poly [ADP-ribose] polymerase 32.4.2.300.466
3ko3ADPD-tyrosyl-tRNA(Tyr) deacylase/0.466
4eyb0WOMetallo-beta-lactamase type 2/0.466
4i5xFLFAldo-keto reductase family 1 member B101.1.10.466
4jtrIZPAldo-keto reductase family 1 member C2/0.466
1b2rFADFerredoxin--NADP reductase1.18.1.20.465
1ihiIU5Aldo-keto reductase family 1 member C2/0.465
1nquRDL6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.465
3nn6HNK6-hydroxy-L-nicotine oxidase/0.465
3r8hZOMAldo-keto reductase family 1 member C3/0.465
4bjcRPBTankyrase-22.4.2.300.465
4jq1NPSAldo-keto reductase family 1 member C2/0.465
1sm4FADFerredoxin--NADP reductase/0.464
2jgbMGTEukaryotic translation initiation factor 4E type 2/0.464
2p1v5TNRetinoic acid receptor RXR-alpha/0.464
3mhpFADFerredoxin--NADP reductase, leaf isozyme, chloroplastic1.18.1.20.464
1px0RPNHalohydrin dehalogenase/0.463
1uzwCDHIsopenicillin N synthase1.21.3.10.463
2vcmM11Isopenicillin N synthase1.21.3.10.463
3dlaNXXGlutamine-dependent NAD(+) synthetase6.3.5.10.463
3dz6M8ES-adenosylmethionine decarboxylase proenzyme4.1.1.500.463
4b65NDPL-ornithine N(5)-monooxygenase/0.463
4ia05BBcGMP-specific 3',5'-cyclic phosphodiesterase/0.463
4j531J4Serine/threonine-protein kinase PLK12.7.11.210.463
1efyBZCPoly [ADP-ribose] polymerase 12.4.2.300.462
1v3q2DIPurine nucleoside phosphorylase2.4.2.10.462
2ipiAKYAclacinomycin-N/aclacinomycin-A oxidase/0.462
2pdfZSTAldose reductase1.1.1.210.462
2vq3NAPMetalloreductase STEAP3/0.462
3r43ID8Aldo-keto reductase family 1 member C3/0.462
4jpg1OXPyruvate kinase PKM2.7.1.400.462
1dgbNDPCatalase1.11.1.60.461
1g3mPCQEstrogen sulfotransferase2.8.2.40.461
1queFADFerredoxin--NADP reductase1.18.1.20.461
1uhlMEIRetinoic acid receptor RXR-beta/0.461
3bjcWANcGMP-specific 3',5'-cyclic phosphodiesterase/0.461
3gyf51PDihydrofolate reductase1.5.1.30.461
3n3zIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.461
3sfxJANUncharacterized protein/0.461
4blcNDPCatalase1.11.1.60.461
4qtnNNRNicotinamide riboside transporter PnuC/0.461
2p99YE6Methionine aminopeptidase/0.460
2rqfJH3Hemolymph juvenile hormone binding protein/0.460
2wo7ASVIsopenicillin N synthase1.21.3.10.460
2zozETTranscriptional regulator/0.460
3d74NBBPheromone-binding protein ASP1/0.460
3k47D09Dihydrofolate reductase1.5.1.30.460
3qiyQI1Botulinum neurotoxin type A3.4.24.690.460
3w3lRX8Toll-like receptor 8/0.460
4cthRDFNeprilysin/0.460
4j3mAJ8Tankyrase-22.4.2.300.460
4r08URIToll-like receptor 8/0.460
4rtbSAMPutative thiazole biosynthesis protein ThiH/0.460
2f59INI6,7-dimethyl-8-ribityllumazine synthase 1/0.459
3d80Q22Dihydrofolate reductase1.5.1.30.459
3dyqIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.459
4a4l939Serine/threonine-protein kinase PLK12.7.11.210.459
4b64NAPL-ornithine N(5)-monooxygenase/0.459
4l8vNAPInositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase1.1.1.180.459
1dghNDPCatalase1.11.1.60.458
1gj5130Prothrombin3.4.21.50.458
1r5hAO2Methionine aminopeptidase 2/0.458
1s36CEIObelin/0.458
2c94TSF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.458
2geuCOKPantothenate kinase2.7.1.330.458
2r6jNDPEugenol synthase 11.1.1.3180.458
3nh8DC2N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming)3.5.1.1140.458
4jtqFLPAldo-keto reductase family 1 member C2/0.458
4msg2C6Tankyrase-12.4.2.300.458
7catNDPCatalase1.11.1.60.458
1ah3TOLAldose reductase1.1.1.210.457
1isjNMNADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 23.2.2.60.457
1kf6HQOFumarate reductase iron-sulfur subunit1.3.5.10.457
1kf6HQOFumarate reductase subunit C/0.457
1kf6HQOFumarate reductase subunit D/0.457
2p1u4TNRetinoic acid receptor RXR-alpha/0.457
3k4551PDihydrofolate reductase1.5.1.30.457
3ugrIMNAldo-keto reductase family 1 member C3/0.457
3vo2FADFerredoxin--NADP reductase/0.457
4k4eK4ETankyrase-12.4.2.300.457
4m6l21VDihydrofolate reductase1.5.1.30.457
4r07URIToll-like receptor 8/0.457
5e9eANPMyosin heavy chain kinase A2.7.11.70.457
5ilwURIRibosome inactivating protein/0.457
1bk0ACVIsopenicillin N synthase1.21.3.10.456
1dr4HBIDihydrofolate reductase1.5.1.30.456
1ot3THMDeoxynucleoside kinase/0.456
1w6jR71Lanosterol synthase5.4.99.70.456
2iejS48Protein farnesyltransferase subunit beta2.5.1.580.456
2pb1NFGGlucan 1,3-beta-glucosidase/0.456
2r6kGTXGlutathione S-transferase A12.5.1.180.456
2tplHPPTyrosine phenol-lyase4.1.99.20.456
2yatEEUEstrogen receptor/0.456
3gg2UGASugar dehydrogenase, UDP-glucose/GDP-mannose dehydrogenase family/0.456
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.456
3p0fBAUUridine phosphorylase 22.4.2.30.456
4khnXG4DNA-directed DNA polymerase/0.456
4mt92D6Tankyrase-12.4.2.300.456
4oew5IOcGMP-specific 3',5'-cyclic phosphodiesterase/0.456
5arkUMPRibonuclease 43.1.270.456
1uk0FRMPoly [ADP-ribose] polymerase 12.4.2.300.455
1w1wAGSStructural maintenance of chromosomes protein 1/0.455
2fzdTOLAldose reductase1.1.1.210.455
2vdyHCYCorticosteroid-binding globulin/0.455
2yp0OVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.455
3b82NADExotoxin A2.4.2.360.455
3p9tTCLRepressor/0.455
4ey6GNTAcetylcholinesterase3.1.1.70.455
4r5wXAVPoly [ADP-ribose] polymerase 12.4.2.300.455
1exa394Retinoic acid receptor gamma/0.454
1go2FADFerredoxin--NADP reductase1.18.1.20.454
1kyxCRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.454
1yw9A84Methionine aminopeptidase 2/0.454
2d06ESTSulfotransferase 1A12.8.2.10.454
2d2gDZZPhosphotriesterase/0.454
3l7gM44Xaa-Pro dipeptidase3.4.13.90.454
3qwc98PProthrombin3.4.21.50.454
4jhiEMUNodulin-13/0.454
1s3uTQDDihydrofolate reductase1.5.1.30.453
1yc2APRNAD-dependent protein deacylase 2/0.453
2ckmAA7Acetylcholinesterase3.1.1.70.453
2f2sCOAAcetyl-CoA acetyltransferase, mitochondrial2.3.1.90.453
2vbpVB1Isopenicillin N synthase1.21.3.10.453
3h0vM2TS-adenosylmethionine decarboxylase proenzyme4.1.1.500.453
3ko5ADPD-tyrosyl-tRNA(Tyr) deacylase/0.453
3pahXDEPhenylalanine-4-hydroxylase1.14.16.10.453
3q7fED2Uncharacterized protein/0.453
4a4o664Serine/threonine-protein kinase PLK12.7.11.210.453
4b117I1Glycylpeptide N-tetradecanoyltransferase/0.453
4lsjLSJGlucocorticoid receptor/0.453
4mdkU94Ubiquitin-conjugating enzyme E2 R1/0.453
8catNDPCatalase1.11.1.60.453
1cq6PY4Aspartate aminotransferase2.6.1.10.452
1gm8SOXPenicillin G acylase3.5.1.110.452
1nqvLMZ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.452
1ps9MDE2,4-dienoyl-CoA reductase1.3.1.340.452
1xf0ASDAldo-keto reductase family 1 member C3/0.452
2w6cBM4Acetylcholinesterase3.1.1.70.452
2z2w770Wee1-like protein kinase2.7.10.20.452
3lqlLDTAldose reductase1.1.1.210.452
4bj9UHBTankyrase-22.4.2.300.452
4fllYZ6Methionine aminopeptidase 1/0.452
4jqaID8Aldo-keto reductase family 1 member C2/0.452
4jvlESTEstrogen sulfotransferase2.8.2.40.452
4xt8TMQPossible bifunctional enzyme riboflavin biosynthesis protein RibD: diaminohydroxyphosphoribosylaminopyrimidine deaminase (Riboflavin-specific deaminase) + 5-amino-6-(5-phosphoribosylamino)uracil reduc/0.452
1bx0FADFerredoxin--NADP reductase, chloroplastic1.18.1.20.451
1j0b5PAPutative 1-aminocyclopropane-1-carboxylate deaminase3.5.99.70.451
1lgtBP3Biphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.451
1rr6IMHPurine nucleoside phosphorylase2.4.2.10.451
2b04CHOPhospholipase A2, major isoenzyme3.1.1.40.451
3nu03TUDihydrofolate reductase1.5.1.30.451
3seqNXXGlutamine-dependent NAD(+) synthetase6.3.5.10.451
4ba5PXGProbable aminotransferase/0.451
4flkY10Methionine aminopeptidase 1/0.451
4j7gTRHPCZA361.3/0.451
4k30NLGN-acetylglutamate synthase, mitochondrial2.3.1.10.451
4y6nUPGGlucosyl-3-phosphoglycerate synthase2.4.1.2660.451
1bx1FADFerredoxin--NADP reductase, chloroplastic1.18.1.20.450
1i5rHYCEstradiol 17-beta-dehydrogenase 11.1.1.620.450
1kmvLIIDihydrofolate reductase1.5.1.30.450
1w87FADFerredoxin--NADP reductase1.18.1.20.450
1zuaTOLAldo-keto reductase family 1 member B101.1.10.450
2nnqT4BFatty acid-binding protein, adipocyte/0.450
3lfcZ86Mitogen-activated protein kinase 14/0.450
3t0kDCQSulfide-quinone reductase/0.450
4cbyKEEHistone deacetylase 43.5.1.980.450
4dbs0HVAldo-keto reductase family 1 member C3/0.450
4wljIK2Kynurenine--oxoglutarate transaminase 12.6.1.70.450
4z87GDPInosine-5'-monophosphate dehydrogenase/0.450
1fvpFMANon-fluorescent flavoprotein/0.449
1gaqFADFerredoxin/0.449
1m3qANGN-glycosylase/DNA lyase3.2.20.449
2bf7HBIPteridine reductase 11.5.1.330.449
2fjm073Tyrosine-protein phosphatase non-receptor type 13.1.3.480.449
2pdaTPPPyruvate synthase/0.449
2pdq47DAldose reductase1.1.1.210.449
2zevIPEGeranylgeranyl pyrophosphate synthase/0.449
3ebiBEYM1 family aminopeptidase3.4.110.449
3zv7NHGAcetylcholinesterase3.1.1.70.449
4b68NAPL-ornithine N(5)-monooxygenase/0.449
4g1nNZTPyruvate kinase PKM2.7.1.400.449
4tnzTTPDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.449
4y9xUPGGlucosyl-3-phosphoglycerate synthase2.4.1.2660.449
5a4wQCTGlutathione S-transferase F22.5.1.180.449
1fkgSB3Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.448
1hfqMOTDihydrofolate reductase1.5.1.30.448
1x2eATXProline iminopeptidase3.4.11.50.448
1y2bDEEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.448
1zhyCLROxysterol-binding protein homolog 4/0.448
2ourCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.448
2qt0NNRNicotinamide riboside kinase 1/0.448
3cv6HXSAldo-keto reductase family 1 member C21/0.448
3djlFADPutative acyl-CoA dehydrogenase AidB1.3.990.448
3f8sPF2Dipeptidyl peptidase 4/0.448
3nxyD2HDihydrofolate reductase1.5.1.30.448
3q0uLL3HTH-type transcriptional regulator EthR/0.448
4g2yNI5cGMP-specific 3',5'-cyclic phosphodiesterase/0.448
4gddNAIUDP-galactopyranose mutase/0.448
4kq6DLZ6,7-dimethyl-8-ribityllumazine synthase/0.448
4p9dTMPDeoxycytidylate deaminase/0.448
4to2DGTDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.448
4x9dU5PUncharacterized protein MJ1435/0.448
5liu388Aldo-keto reductase family 1 member B101.1.10.448
1b9iPXG3-amino-5-hydroxybenzoate synthase4.2.1.1440.447
1dp2LPBThiosulfate sulfurtransferase/0.447
1enoNADEnoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic1.3.1.90.447
1kyyINI6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.447
1s7gAPRNAD-dependent protein deacylase 2/0.447
1t7o152Carnitine O-acetyltransferase2.3.1.70.447
2aj4ANPGalactokinase2.7.1.60.447
2ouyCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.447
2xnoED8Serine/threonine-protein kinase Nek22.7.11.10.447
3dhaC6LN-acyl homoserine lactonase AiiA3.1.1.810.447
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.447
3exnACOProbable acetyltransferase/0.447
3qi4IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.447
4jsr1NQNAD-dependent protein deacetylase sirtuin-3, mitochondrial3.5.10.447
4kp61S1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.447
4n9qFMNFMN-dependent NADH-azoreductase 1/0.447
4ug5H4BNitric oxide synthase oxygenase1.14.13.1650.447
4xo7ASDAldo-keto reductase family 1 member C2/0.447
5fuwTHMThymidine kinase, putative/0.447
1d7oTCLEnoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic1.3.1.90.446
1hfrMOTDihydrofolate reductase1.5.1.30.446
1ib0FADNADH-cytochrome b5 reductase 31.6.2.20.446
1klkPMDDihydrofolate reductase1.5.1.30.446
1p4r354Bifunctional purine biosynthesis protein PURH2.1.2.30.446
1pd9CO4Dihydrofolate reductase1.5.1.30.446
1r5gAO1Methionine aminopeptidase 2/0.446
1u65CP0Acetylcholinesterase3.1.1.70.446
1w35FADFerredoxin--NADP reductase1.18.1.20.446
1z4iUMP5'(3')-deoxyribonucleotidase, mitochondrial3.1.30.446
1z5uCMPClass B acid phosphatase/0.446
2a57CRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.446
2b8jADNClass B acid phosphatase3.1.3.20.446
2imkGTXAGAP009194-PA/0.446
2io6330Wee1-like protein kinase2.7.10.20.446
2ipjFFAAldo-keto reductase family 1 member C2/0.446
2nm2NEUDihydroneopterin aldolase/0.446
2rkuR78Serine/threonine-protein kinase PLK12.7.11.210.446
2vt4P32Beta-1 adrenergic receptor/0.446
2wzySQXSoluble acetylcholine receptor/0.446
3casASD3-oxo-5-beta-steroid 4-dehydrogenase/0.446
3cqeP91Wee1-like protein kinase2.7.10.20.446
3dylIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.446
3e4aQIXInsulin-degrading enzyme3.4.24.560.446
3hv3R49Mitogen-activated protein kinase 14/0.446
3lutNAPVoltage-gated potassium channel subunit beta-2/0.446
3nt5NAIInositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase1.1.1.180.446
3v3nMIYTetX family tetracycline inactivation enzyme/0.446
3zkyWT4Isopenicillin N synthase1.21.3.10.446
4a33PS8Glycylpeptide N-tetradecanoyltransferase/0.446
4gv8DUPDUTPase/0.446
4j521J3Serine/threonine-protein kinase PLK12.7.11.210.446
4jvnYUGEstrogen sulfotransferase2.8.2.40.446
1dd6MCIMetallo-beta-lactamase type 2/0.445
1i7cMGBS-adenosylmethionine decarboxylase proenzyme4.1.1.500.445
2evcFC3Methionine aminopeptidase/0.445
2fzbTOLAldose reductase1.1.1.210.445
2gbyBRNHTH-type transcriptional regulator QacR/0.445
2w3aTOPDihydrofolate reductase1.5.1.30.445
3h1qATPEthanolamine utilization protein EutJ/0.445
3l3rOAGDihydrofolate reductase1.5.1.30.445
3mjrAC2Deoxycytidine kinase2.7.1.740.445
3o9lLPNRenin3.4.23.150.445
3ug8IMNAldo-keto reductase family 1 member C3/0.445
4kn0MTXFolate receptor beta/0.445
4li81XQTankyrase-12.4.2.300.445
4u95MIYMultidrug efflux pump subunit AcrB/0.445
1dmwHBIPhenylalanine-4-hydroxylase1.14.16.10.444
1ej3CZHAequorin-2/0.444
1esmCOAPantothenate kinase2.7.1.330.444
1q13TESProstaglandin-E(2) 9-reductase1.1.1.1890.444
1rx3MTXDihydrofolate reductase1.5.1.30.444
1xm1GAHProthrombin3.4.21.50.444
1y6rMTM5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase3.2.2.90.444
1yciNDFHypoxia-inducible factor 1-alpha inhibitor1.14.11.300.444
1zgcA2EAcetylcholinesterase3.1.1.70.444
2h7jH7JCathepsin S3.4.22.270.444
2pdlTOLAldose reductase1.1.1.210.444
2xk4OL2Serine/threonine-protein kinase Nek22.7.11.10.444
3bxoUPPdTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose/0.444
3cotSTR3-oxo-5-beta-steroid 4-dehydrogenase/0.444
3ituIBMcGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.444
3nytULPUDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase2.6.1.980.444
3pn1IVHDNA ligase/0.444
3sqwANPATP-dependent RNA helicase MSS116, mitochondrial3.6.4.130.444
4arbC57Acetylcholinesterase3.1.1.70.444
4boeCLRJapanin/0.444
4cb4MGTPolymerase basic protein 2/0.444
4dch4DCGlucokinase2.7.1.20.444
4fwnAQPPropionate kinase/0.444
4n82FMNRibonucleotide reductase (NrdI family protein), putative/0.444
4nbn2J7Caspase-63.4.22.590.444
1dhfFOLDihydrofolate reductase1.5.1.30.443
1dpmEBPParathion hydrolase3.1.8.10.443
1h42FADFerredoxin--NADP reductase1.18.1.20.443
1jf2CZHObelin/0.443
1odnAPVIsopenicillin N synthase1.21.3.10.443
1po7TZDBenzoylformate decarboxylase4.1.1.70.443
1thnADPAnti-sigma F factor/0.443
1y60H4M5,6,7,8-tetrahydromethanopterin hydro-lyase4.2.1.1470.443
2iqdLPAAldose reductase1.1.1.210.443
2j3qTFLAcetylcholinesterase3.1.1.70.443
2zu9GDPMannosyl-3-phosphoglycerate synthase2.4.1.2170.443
3b78NADExotoxin A2.4.2.360.443
3c4hDRLPoly [ADP-ribose] polymerase 32.4.2.300.443
3gdpFAD(R)-mandelonitrile lyase 24.1.2.100.443
3l3lL3LPoly [ADP-ribose] polymerase 12.4.2.300.443
3qj0QI3Botulinum neurotoxin type A3.4.24.690.443
3tg4SAMN-lysine methyltransferase SMYD2/0.443
4g2wNI0cGMP-specific 3',5'-cyclic phosphodiesterase/0.443
4jq4IMNAldo-keto reductase family 1 member C2/0.443
4jt81NRNAD-dependent protein deacetylase sirtuin-3, mitochondrial3.5.10.443
4kn104JFolate receptor beta/0.443
4twlASCDioscorin 5/0.443
4zhiADPKinesin-like protein KIF11/0.443
1g63FMNEpidermin decarboxylase4.1.10.442
1isgAGSADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 23.2.2.60.442
1ni4TPPPyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial1.2.4.10.442
1ni4TPPPyruvate dehydrogenase E1 component subunit beta, mitochondrial1.2.4.10.442
1o2g696Prothrombin3.4.21.50.442
1qsnCOAHAT A1/0.442
2v7qADPATP synthase subunit beta, mitochondrial3.6.3.140.442
3c3xNAPEugenol synthase 11.1.1.3180.442
3n3aFMNProtein NrdI/0.442
3uicNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.442
3zecANPAdenosine monophosphate-protein transferase SoFic2.7.7.n10.442
3zlmANPAdenosine monophosphate-protein transferase NmFic2.7.7.n10.442
3zrbOR8Progesterone receptor/0.442
4b144XBGlycylpeptide N-tetradecanoyltransferase/0.442
4b63NAPL-ornithine N(5)-monooxygenase/0.442
4ckcSAHmRNA-capping enzyme catalytic subunit2.1.1.560.442
4dyp0MSNucleoprotein/0.442
4eilFOLBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.442
4f0e0RUPoly [ADP-ribose] polymerase 152.4.2.300.442
4gh10WXQueuine tRNA-ribosyltransferase2.4.2.290.442
4jq2SUZAldo-keto reductase family 1 member C2/0.442
4ms1381Gamma-aminobutyric acid type B receptor subunit 1/0.442
4oex5EOcGMP-specific 3',5'-cyclic phosphodiesterase/0.442
4pmjNAPPutative oxidoreductase/0.442
1h22E10Acetylcholinesterase3.1.1.70.441
1ni1HFPProtein farnesyltransferase subunit beta2.5.1.580.441
1og1TADT-cell ecto-ADP-ribosyltransferase 2/0.441
1uwhBAXSerine/threonine-protein kinase B-raf2.7.11.10.441
1xzqFONtRNA modification GTPase MnmE3.6.50.441
1zklIBMHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A3.1.4.530.441
2hdjNDPAldo-keto reductase family 1 member C2/0.441
2j7dGI1Beta-glucosidase A3.2.1.210.441
2opbF21Phenylethanolamine N-methyltransferase2.1.1.280.441
2q2zADPKinesin-like protein KIF11/0.441
2w3mFOLDihydrofolate reductase1.5.1.30.441
3c6n2S8Protein TRANSPORT INHIBITOR RESPONSE 1/0.441
3cvkN34Genome polyprotein2.7.7.480.441
3dzjNMNADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 13.2.2.60.441
3fr5I4AFatty acid-binding protein, adipocyte/0.441
3ghtLDTAldose reductase1.1.1.210.441
3llaACPMyosin heavy chain kinase A2.7.11.70.441
3qbwADPAnhydro-N-acetylmuramic acid kinase/0.441
4ax8SAMO-antigen chain terminator bifunctional methyltransferase/kinase WbdD/0.441
4b67NAPL-ornithine N(5)-monooxygenase/0.441
4bjbP34Tankyrase-22.4.2.300.441
4ckrDI1Epithelial discoidin domain-containing receptor 12.7.10.10.441
4h7c10HAldo-keto reductase family 1 member C3/0.441
4kbyC2EStimulator of interferon genes protein/0.441
4m6kFOLDihydrofolate reductase1.5.1.30.441
4mrm2BYGamma-aminobutyric acid type B receptor subunit 1/0.441
5c1gGDUHisto-blood group ABO system transferase/0.441
1bqoN25Stromelysin-13.4.24.170.440
1e63FADFerredoxin--NADP reductase1.18.1.20.440
1gr1FADFerredoxin--NADP reductase1.18.1.20.440
1i59ANPChemotaxis protein CheA2.7.13.30.440
1lrmHBIPhenylalanine-4-hydroxylase1.14.16.10.440
1m67BOAGlycerol-3-phosphate dehydrogenase [NAD(+)], glycosomal1.1.1.80.440
1yw8A75Methionine aminopeptidase 2/0.440
1zgbA1EAcetylcholinesterase3.1.1.70.440
2b35NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.440
2bxqIMNSerum albumin/0.440
2evmFC2Methionine aminopeptidase/0.440
2jb4A14Isopenicillin N synthase1.21.3.10.440
2pucGUNHTH-type transcriptional repressor PurR/0.440
2x7tWZBCarbonic anhydrase 24.2.1.10.440
3bmqAX5Pteridine reductase/0.440
3d5wADPSerine/threonine-protein kinase PLK/0.440
3dwbRDFEndothelin-converting enzyme 13.4.24.710.440
3gxfIFMGlucosylceramidase3.2.1.450.440
3iej599Cathepsin S3.4.22.270.440
3jypNADQuinate/shikimate dehydrogenase (NAD(+))/0.440
4dbuBT9Aldo-keto reductase family 1 member C3/0.440
4gi40EXQueuine tRNA-ribosyltransferase2.4.2.290.440
4h6zACOAlpha-tubulin N-acetyltransferase 1/0.440
4iilRBFMembrane lipoprotein TpN38(b)/0.440
4uthFMNXenobiotic reductase/0.440
5kf2ACOPredicted acetyltransferase/0.440