sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4e9a | QAP | Peptide deformylase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4e9a | QAP | Peptide deformylase | / | 1.000 | |
| 2ew5 | Y12 | Peptide deformylase | / | 0.642 | |
| 2ew6 | Y13 | Peptide deformylase | / | 0.624 | |
| 3m6p | BB2 | Peptide deformylase 1B, chloroplastic/mitochondrial | 3.5.1.88 | 0.614 | |
| 3pn4 | BB2 | Peptide deformylase 1B, chloroplastic/mitochondrial | 3.5.1.88 | 0.580 | |
| 3u04 | BB2 | Peptide deformylase | / | 0.560 | |
| 1ix1 | BB2 | Peptide deformylase | / | 0.553 | |
| 1g2a | BB2 | Peptide deformylase | 3.5.1.88 | 0.536 | |
| 3o3j | BB4 | Peptide deformylase 1B, chloroplastic/mitochondrial | 3.5.1.88 | 0.521 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.508 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.504 | |
| 4kuh | CAA | 3-hydroxybutyryl-CoA dehydrogenase | / | 0.503 | |
| 1lru | BB2 | Peptide deformylase | 3.5.1.88 | 0.496 | |
| 2pr2 | DG1 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.495 | |
| 1s17 | GNR | Peptide deformylase | / | 0.493 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.493 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.490 | |
| 1g27 | BB1 | Peptide deformylase | 3.5.1.88 | 0.489 | |
| 1ws1 | BB2 | Peptide deformylase 1 | / | 0.487 | |
| 4ew3 | DXZ | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.486 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.485 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.484 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.481 | |
| 4ejm | NAP | Putative zinc-binding dehydrogenase | / | 0.481 | |
| 1h73 | ANP | Homoserine kinase | 2.7.1.39 | 0.479 | |
| 1jnr | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.479 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.477 | |
| 3qls | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.477 | |
| 4e9b | BB2 | Peptide deformylase | / | 0.477 | |
| 2npx | NAD | NADH peroxidase | 1.11.1.1 | 0.476 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.476 | |
| 2hy8 | 1ST | Serine/threonine-protein kinase PAK 1 | 2.7.11.1 | 0.475 | |
| 1kvk | ATP | Mevalonate kinase | 2.7.1.36 | 0.473 | |
| 1y0s | 331 | Peroxisome proliferator-activated receptor delta | / | 0.473 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.473 | |
| 3uwb | BB2 | RIIA-RIIB membrane-associated protein | / | 0.473 | |
| 4eag | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.473 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.472 | |
| 2cmj | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.471 | |
| 3zuy | TCH | Transporter | / | 0.471 | |
| 5ecc | NAP | Dehydrofolate reductase type I | / | 0.471 | |
| 1juv | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.470 | |
| 1qor | NDP | Quinone oxidoreductase 1 | / | 0.470 | |
| 2j5x | GSP | ADP-ribosylation factor 6 | / | 0.470 | |
| 4cfa | WOP | Integrase | / | 0.470 | |
| 4nie | NBH | Nuclear receptor ROR-gamma | / | 0.470 | |
| 1phh | FAD | p-hydroxybenzoate hydroxylase | / | 0.469 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.469 | |
| 2y3r | TRK | TamL | / | 0.468 | |
| 3iod | A6D | Pantothenate synthetase | 6.3.2.1 | 0.468 | |
| 4pvd | NDP | NADPH-dependent methylglyoxal reductase GRE2 | / | 0.468 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.467 | |
| 1ia1 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
| 3ig6 | 438 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.467 | |
| 3oib | FDA | Putative acyl-CoA dehydrogenase | / | 0.467 | |
| 4h8n | NDP | NADPH-dependent conjugated polyketone reductase C2 | / | 0.467 | |
| 4ri1 | ACO | UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase | 2.3.1.202 | 0.467 | |
| 2q8s | L92 | Peroxisome proliferator-activated receptor gamma | / | 0.466 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.466 | |
| 3jun | AKD | Phenazine biosynthesis protein A/B | / | 0.466 | |
| 4a32 | 2CD | Glycylpeptide N-tetradecanoyltransferase | / | 0.466 | |
| 4asj | N6A | Glucose-1-phosphate thymidylyltransferase | / | 0.466 | |
| 4l8u | 9AZ | Serum albumin | / | 0.466 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.465 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.465 | |
| 4f4d | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.465 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.464 | |
| 3v94 | WYQ | Phosphodiesterase | / | 0.464 | |
| 1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.463 | |
| 3hdm | MMG | Serine/threonine-protein kinase Sgk1 | 2.7.11.1 | 0.463 | |
| 4e5y | NDP | GDP-L-fucose synthase | 1.1.1.271 | 0.463 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.462 | |
| 2izr | BRK | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.462 | |
| 3f63 | GTX | Glutathione transferase GST1-4 | / | 0.462 | |
| 4ftt | 6HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.462 | |
| 4pd6 | URI | Nucleoside permease | / | 0.462 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.462 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.461 | |
| 1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.461 | |
| 2b0m | 201 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.461 | |
| 2eba | FAD | Putative glutaryl-CoA dehydrogenase | / | 0.461 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.461 | |
| 3bw4 | FMN | Putative 2-nitropropane dioxygenase | / | 0.461 | |
| 3e3u | NVC | Peptide deformylase | 3.5.1.88 | 0.461 | |
| 4b4g | KKT | Glucose-1-phosphate thymidylyltransferase | / | 0.461 | |
| 5koi | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.461 | |
| 1mcz | RMN | Benzoylformate decarboxylase | 4.1.1.7 | 0.460 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.460 | |
| 1u4o | NDD | L-lactate dehydrogenase | 1.1.1.27 | 0.459 | |
| 2c54 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.459 | |
| 2ejz | SAH | Diphthine synthase | / | 0.459 | |
| 2uxh | QUE | HTH-type transcriptional regulator TtgR | / | 0.459 | |
| 2zu9 | GDP | Mannosyl-3-phosphoglycerate synthase | 2.4.1.217 | 0.459 | |
| 3dey | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.459 | |
| 3ikt | NAD | Redox-sensing transcriptional repressor Rex | / | 0.459 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.459 | |
| 3klm | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.459 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.459 | |
| 4i8v | BHF | Cytochrome P450 1A1 | 1.14.14.1 | 0.459 | |
| 4oh4 | ANP | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.459 | |
| 4zir | ANP | Energy-coupling factor transporter ATP-binding protein EcfA2 | 3.6.3 | 0.459 | |
| 4zir | ANP | Energy-coupling factor transporter ATP-binding protein EcfA1 | / | 0.459 | |
| 1jkx | 138 | Phosphoribosylglycinamide formyltransferase | / | 0.458 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.458 | |
| 2hg1 | N5O | Endoplasmin | / | 0.458 | |
| 2o12 | FMN | Chorismate synthase | / | 0.457 | |
| 3jzd | NAD | Maleylacetate reductase | / | 0.457 | |
| 3r83 | Z14 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.457 | |
| 3uax | NOS | Purine nucleoside phosphorylase DeoD-type | / | 0.457 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.457 | |
| 4bcr | WY1 | Peroxisome proliferator-activated receptor alpha | / | 0.457 | |
| 5dqr | FAD | 7-hydroxymethyl chlorophyll a reductase, chloroplastic | 1.17.7.2 | 0.457 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.456 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.456 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.456 | |
| 1ppj | ANY | Cytochrome b | / | 0.456 | |
| 3eks | CY9 | Actin-5C | / | 0.456 | |
| 3nxx | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.456 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.456 | |
| 3zei | AWH | O-acetylserine sulfhydrylase | / | 0.456 | |
| 4a87 | NAR | Major pollen allergen Bet v 1-A | / | 0.456 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.456 | |
| 1qlh | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.455 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.455 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 3a3b | RBF | Lumazine protein | / | 0.455 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.455 | |
| 3q44 | D50 | M1 family aminopeptidase | 3.4.11 | 0.455 | |
| 1e7q | NAP | GDP-L-fucose synthase | / | 0.454 | |
| 2x06 | NAD | L-sulfolactate dehydrogenase | / | 0.454 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.454 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.454 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.454 | |
| 4xd2 | NAI | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.454 | |
| 1bxk | NAD | dTDP-glucose 4,6-dehydratase 2 | / | 0.453 | |
| 1eio | GCH | Gastrotropin | / | 0.453 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.453 | |
| 2uyw | BTN | Avd protein | / | 0.453 | |
| 2wd9 | IBP | Acyl-coenzyme A synthetase ACSM2A, mitochondrial | 6.2.1.2 | 0.453 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.453 | |
| 3s5w | FAD | L-ornithine N(5)-monooxygenase | / | 0.453 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.453 | |
| 4f9f | GDP | Putative glycosyltransferase | / | 0.453 | |
| 4gyy | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.453 | |
| 1e5q | NDP | Saccharopine dehydrogenase [NADP(+), L-glutamate-forming] | 1.5.1.10 | 0.452 | |
| 1k7f | IAV | Tryptophan synthase alpha chain | / | 0.452 | |
| 1vik | BAY | Gag-Pol polyprotein | / | 0.452 | |
| 2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.452 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.452 | |
| 3ioc | A5D | Pantothenate synthetase | 6.3.2.1 | 0.452 | |
| 3zbr | NAP | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.452 | |
| 4xgx | ADP | FAD:protein FMN transferase | / | 0.452 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.452 | |
| 5kjc | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.452 | |
| 1adf | TAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.451 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.451 | |
| 2e0n | SAH | Precorrin-2 C20-methyltransferase | / | 0.451 | |
| 2emu | SAH | Diphthine synthase | / | 0.451 | |
| 2gtn | LIE | Mitogen-activated protein kinase 14 | / | 0.451 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.451 | |
| 2q4b | NAP | Uncharacterized protein At5g02240 | / | 0.451 | |
| 2rcy | NAP | Pyrroline-5-carboxylate reductase | / | 0.451 | |
| 2z1m | NDP | GDP-mannose 4,6-dehydratase | / | 0.451 | |
| 3ad9 | NAD | Subunit alpha of sarocosine oxidase | / | 0.451 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.451 | |
| 3pe2 | E1B | Casein kinase II subunit alpha | 2.7.11.1 | 0.451 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.451 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.451 | |
| 4ew2 | DXY | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.451 | |
| 4hgl | 0YO | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.451 | |
| 1c7o | PPG | Hemolysin | / | 0.450 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.450 | |
| 1ma0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.450 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.450 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.450 | |
| 2cig | 1DG | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 2dft | ADP | Shikimate kinase | 2.7.1.71 | 0.450 | |
| 2uxu | NAR | HTH-type transcriptional regulator TtgR | / | 0.450 | |
| 2z7h | GG3 | Geranylgeranyl pyrophosphate synthase | / | 0.450 | |
| 2zb3 | NDP | Prostaglandin reductase 2 | 1.3.1.48 | 0.450 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.450 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.450 | |
| 3ime | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.450 | |
| 3ox4 | NAD | Alcohol dehydrogenase 2 | 1.1.1.1 | 0.450 | |
| 3r32 | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.450 | |
| 3v3m | 0EN | Replicase polyprotein 1a | 3.4.19.12 | 0.450 | |
| 4a31 | 2CB | Glycylpeptide N-tetradecanoyltransferase | / | 0.450 | |
| 4a6r | TA8 | Probable aminotransferase | / | 0.450 | |
| 4at0 | FAD | Possible succinate dehydrogenase | / | 0.450 | |
| 4b2w | BZ0 | Glucose-1-phosphate thymidylyltransferase | / | 0.450 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.450 | |
| 4i9n | 1E5 | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.450 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.450 | |
| 2aq8 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.449 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 3bc3 | OPT | Cathepsin L1 | 3.4.22.15 | 0.449 | |
| 3dop | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.449 | |
| 3i59 | N6S | CRP-like cAMP-activated global transcriptional regulator | / | 0.449 | |
| 4nb6 | 444 | Nuclear receptor ROR-gamma | / | 0.449 | |
| 1rx1 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1w4a | APC | NTPase P4 | / | 0.448 | |
| 2bl4 | NAD | Lactaldehyde reductase | 1.1.1.77 | 0.448 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.448 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
| 3h06 | VBP | Glutamate receptor 2 | / | 0.448 | |
| 3rvh | HQ2 | Lysine-specific demethylase 4A | 1.14.11 | 0.448 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.448 | |
| 4az3 | S35 | Lysosomal protective protein | 3.4.16.5 | 0.448 | |
| 4ftq | 4HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.448 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1h74 | AGS | Homoserine kinase | 2.7.1.39 | 0.447 | |
| 1pjk | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.447 | |
| 1tl7 | ONM | Adenylate cyclase type 2 | / | 0.447 | |
| 1tl7 | ONM | Adenylate cyclase type 5 | / | 0.447 | |
| 1y5r | C0R | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.447 | |
| 2bel | CBO | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.447 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 2ym7 | YM7 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.447 | |
| 3img | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.447 | |
| 3of4 | FMN | Nitroreductase | / | 0.447 | |
| 3p67 | FMN | Pentaerythritol tetranitrate reductase | / | 0.447 | |
| 3q71 | AR6 | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.447 | |
| 4bb6 | HD1 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.447 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.447 | |
| 4ft3 | H1K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.447 | |
| 4hgs | 15G | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.447 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.447 | |
| 4z26 | FAD | Putative GMC-type oxidoreductase R135 | 1 | 0.447 | |
| 1dxy | NAD | D-2-hydroxyisocaproate dehydrogenase | 1.1.1 | 0.446 | |
| 1jay | F42 | F420-dependent NADP reductase | / | 0.446 | |
| 1ps9 | MDE | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.446 | |
| 1rbm | KT5 | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.446 | |
| 1xl8 | 152 | Peroxisomal carnitine O-octanoyltransferase | 2.3.1.137 | 0.446 | |
| 2aa3 | AP0 | L-lactate dehydrogenase | / | 0.446 | |
| 2chx | 090 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.446 | |
| 2cns | ACO | Ribosomal-protein-alanine acetyltransferase | / | 0.446 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.446 | |
| 2prb | COA | Aminoglycoside 6-N-acetyltransferase type Ib11 | / | 0.446 | |
| 2w2l | NAD | D-mandelate dehydrogenase | / | 0.446 | |
| 3cuk | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.446 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.446 | |
| 4b5b | BBE | Glucose-1-phosphate thymidylyltransferase | / | 0.446 | |
| 4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.446 | |
| 4g6h | NAI | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.446 | |
| 4hjf | C2E | GGDEF family protein | / | 0.446 | |
| 4hjo | AQ4 | Epidermal growth factor receptor | 2.7.10.1 | 0.446 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.446 | |
| 4xzj | NAD | Putative NAD(+)--arginine ADP-ribosyltransferase Vis | 2.4.2.31 | 0.446 | |
| 1hdr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.445 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 1rm5 | NDP | Glyceraldehyde-3-phosphate dehydrogenase A, chloroplastic | 1.2.1.13 | 0.445 | |
| 1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.445 | |
| 2brg | DFY | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.445 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.445 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.445 | |
| 2w6z | L21 | Biotin carboxylase | 6.3.4.14 | 0.445 | |
| 2xc3 | RT8 | Steroid C26-monooxygenase | 1.14.13.141 | 0.445 | |
| 3gy0 | NAP | NAD(P)-dependent oxidoreductase | / | 0.445 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 3oew | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.445 | |
| 3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.445 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.445 | |
| 3tne | RIT | Candidapepsin-1 | 3.4.23.24 | 0.445 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.445 | |
| 4cvm | ANP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.445 | |
| 4lcj | NAD | C-terminal-binding protein 2 | / | 0.445 | |
| 4o0l | NDP | NADPH-dependent 3-quinuclidinone reductase | / | 0.445 | |
| 4ynt | FDA | Glucose oxidase, putative | / | 0.445 | |
| 5c3z | ACP | Ribokinase | / | 0.445 | |
| 1bw9 | NAD | Phenylalanine dehydrogenase | / | 0.444 | |
| 1dhr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.444 | |
| 1mg5 | NAI | Alcohol dehydrogenase | 1.1.1.1 | 0.444 | |
| 2in6 | 839 | Wee1-like protein kinase | 2.7.10.2 | 0.444 | |
| 2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.444 | |
| 2z3u | CRR | Cytochrome P450 | / | 0.444 | |
| 2zla | VDB | Vitamin D3 receptor | / | 0.444 | |
| 3b6z | CO7 | Enoyl reductase LovC | 1 | 0.444 | |
| 3gfb | NAD | L-threonine 3-dehydrogenase | / | 0.444 | |
| 3jyn | NDP | Quinone oxidoreductase | / | 0.444 | |
| 3mnr | SD1 | Heat shock protein HSP 90-alpha | / | 0.444 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 3rue | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.444 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.444 | |
| 4fxy | 0W2 | Neurolysin, mitochondrial | 3.4.24.16 | 0.444 | |
| 4ips | 1G4 | Mycocyclosin synthase | 1.14.21.9 | 0.444 | |
| 4m87 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.444 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.444 | |
| 4qi5 | FAD | Cellobiose dehydrogenase | / | 0.444 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.444 | |
| 4z24 | FAD | Putative GMC-type oxidoreductase R135 | 1 | 0.444 | |
| 1bim | 0QB | Renin | 3.4.23.15 | 0.443 | |
| 1d3h | A26 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.443 | |
| 1fxs | NAP | GDP-L-fucose synthase | / | 0.443 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.443 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 1ur5 | NAD | Malate dehydrogenase | / | 0.443 | |
| 2cgv | 3B3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.443 | |
| 2hog | 710 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.443 | |
| 2nn7 | M29 | Carbonic anhydrase 1 | 4.2.1.1 | 0.443 | |
| 2nsd | 4PI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 2w71 | L23 | Biotin carboxylase | 6.3.4.14 | 0.443 | |
| 2yyi | FAD | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component | 1.14.14.9 | 0.443 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.443 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 3jzi | JZL | Biotin carboxylase | 6.3.4.14 | 0.443 | |
| 3kb1 | ADP | Iron-sulfur cluster carrier protein | / | 0.443 | |
| 3tki | S25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.443 | |
| 3wag | TYD | Glycosyltransferase | / | 0.443 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.443 | |
| 4hw3 | 19G | Induced myeloid leukemia cell differentiation protein Mcl-1 | / | 0.443 | |
| 4xrg | NAD | Homospermidine synthase | 2.5.1.44 | 0.443 | |
| 4yau | FAD | NADPH--cytochrome P450 reductase | / | 0.443 | |
| 1dg8 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1dr5 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1lry | BB2 | Peptide deformylase | / | 0.442 | |
| 1rl4 | BRR | Peptide deformylase | / | 0.442 | |
| 1xon | PIL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.442 | |
| 2bd0 | NAP | Sepiapterin reductase | / | 0.442 | |
| 2cch | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 2i4j | DRJ | Peroxisome proliferator-activated receptor gamma | / | 0.442 | |
| 2ie0 | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 2owk | SAH | Diphthine synthase | / | 0.442 | |
| 2w9h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 2znn | S44 | Peroxisome proliferator-activated receptor alpha | / | 0.442 | |
| 3ch6 | 311 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.442 | |
| 3hy7 | 097 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.442 | |
| 3qfc | FAD | NADPH--cytochrome P450 reductase | / | 0.442 | |
| 3rdq | DTB | Streptavidin | / | 0.442 | |
| 3vqs | JT1 | Genome polyprotein | / | 0.442 | |
| 4bv9 | NDP | Ketimine reductase mu-crystallin | 1.5.1.25 | 0.442 | |
| 4do3 | 0LA | Fatty-acid amide hydrolase 1 | 3.5.1.99 | 0.442 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 4em9 | TCE | Peroxisome proliferator-activated receptor gamma | / | 0.442 | |
| 4hbm | 0Y7 | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.442 | |
| 4wdb | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.442 | |
| 4y9l | FAD | Acyl-CoA dehydrogenase family member 11 | / | 0.442 | |
| 5djt | FMN | NPH1-2 | / | 0.442 | |
| 1bdb | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | / | 0.441 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.441 | |
| 1pdh | FAS | p-hydroxybenzoate hydroxylase | / | 0.441 | |
| 1rby | KEU | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.441 | |
| 1zrz | BI1 | Protein kinase C iota type | 2.7.11.13 | 0.441 | |
| 2aqk | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 2bjf | DXC | Choloylglycine hydrolase | 3.5.1.24 | 0.441 | |
| 2c1b | CQP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.441 | |
| 2pb6 | SAH | Diphthine synthase | / | 0.441 | |
| 2y3s | TIR | TamL | / | 0.441 | |
| 3c0g | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.441 | |
| 3maa | FKP | Adenylate cyclase type 2 | / | 0.441 | |
| 3maa | FKP | Adenylate cyclase type 5 | / | 0.441 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 3wle | NAD | (R)-specific carbonyl reductase | / | 0.441 | |
| 4a84 | DXC | Major pollen allergen Bet v 1-A | / | 0.441 | |
| 4i7f | NVE | Gag-Pol polyprotein | 2.7.7.49 | 0.441 | |
| 4jld | ADP | Adenylate kinase | / | 0.441 | |
| 4nh8 | 2LC | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 4rf2 | NAP | NADPH dependent R-specific alcohol dehydrogenase | / | 0.441 | |
| 4rje | FNR | Lactate oxidase | / | 0.441 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 1kqu | BR4 | Phospholipase A2, membrane associated | / | 0.440 | |
| 1rbz | KT5 | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.440 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 1vzb | UMP | Thymidylate synthase | / | 0.440 | |
| 1wnt | NAP | L-xylulose reductase | 1.1.1.10 | 0.440 | |
| 2ehl | SAH | Diphthine synthase | / | 0.440 | |
| 2gfd | RDA | Endoplasmin | / | 0.440 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 2wmv | ZYV | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 2y0m | ACO | Histone acetyltransferase KAT8 | / | 0.440 | |
| 3b70 | NAP | Enoyl reductase LovC | 1 | 0.440 | |
| 3bbt | FMM | Receptor tyrosine-protein kinase erbB-4 | 2.7.10.1 | 0.440 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 3e5a | VX6 | Aurora kinase A | 2.7.11.1 | 0.440 | |
| 3gqv | NAP | Enoyl reductase LovC | 1 | 0.440 | |
| 3h6v | NS6 | Glutamate receptor 2 | / | 0.440 | |
| 3i59 | N6R | CRP-like cAMP-activated global transcriptional regulator | / | 0.440 | |
| 3iel | U5P | Ribonuclease TTHA0252 | 3.1 | 0.440 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.440 | |
| 3ruh | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.440 | |
| 3w33 | W19 | Epidermal growth factor receptor | 2.7.10.1 | 0.440 | |
| 4ejv | LCL | Transcriptional regulator TcaR | / | 0.440 | |
| 4j7u | NAP | Sepiapterin reductase | 1.1.1.153 | 0.440 | |
| 4r21 | STR | Cytochrome P450 family 17 polypeptide 2 | / | 0.440 | |
| 4xqc | NAD | Homospermidine synthase | 2.5.1.44 | 0.440 | |
| 4yt5 | H4M | H(2)-forming methylenetetrahydromethanopterin dehydrogenase-related protein MJ1338 | / | 0.440 | |
| 5dbf | NDP | Iridoid synthase | 1.3.1.99 | 0.440 | |
| 5k2b | ZMA | Adenosine receptor A2a | / | 0.440 |