sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4dkv | 0KW | Envelope glycoprotein gp160 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4dkv | 0KW | Envelope glycoprotein gp160 | / | 1.000 | |
| 4dku | 0KU | Envelope glycoprotein gp160 | / | 0.602 | |
| 3g0y | P9A | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.519 | |
| 4dkp | 0LL | Envelope glycoprotein gp160 | / | 0.516 | |
| 4dvv | 0M1 | Envelope glycoprotein gp160 | / | 0.505 | |
| 5dp2 | NAP | CurF | / | 0.504 | |
| 4dko | 0LM | Envelope glycoprotein gp160 | / | 0.502 | |
| 4jv3 | N32 | Beta-ketoacyl synthase | / | 0.500 | |
| 5doz | NDP | JamJ | / | 0.497 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.491 | |
| 1opb | RET | Retinol-binding protein 2 | / | 0.487 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.481 | |
| 4bcr | WY1 | Peroxisome proliferator-activated receptor alpha | / | 0.480 | |
| 4bfs | ZVS | Pantothenate kinase | 2.7.1.33 | 0.480 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.480 | |
| 1osv | CHC | Bile acid receptor | / | 0.479 | |
| 2b35 | TCL | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.479 | |
| 4bzo | 676 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.479 | |
| 4qzu | RTL | Retinol-binding protein 2 | / | 0.478 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.477 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.476 | |
| 1ppj | ANY | Cytochrome b | / | 0.476 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.475 | |
| 2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.475 | |
| 4jtq | NAP | Aldo-keto reductase family 1 member C2 | / | 0.475 | |
| 4jx1 | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.475 | |
| 4mlp | 2CX | Cryptochrome-2 | / | 0.475 | |
| 4o1m | NAD | Enoyl-acyl carrier reductase | / | 0.475 | |
| 5f8e | SAH | Possible transcriptional regulatory protein | / | 0.474 | |
| 1crb | RTL | Retinol-binding protein 1 | / | 0.473 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.473 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.473 | |
| 4qof | FMN | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.473 | |
| 1qor | NDP | Quinone oxidoreductase 1 | / | 0.472 | |
| 2b4y | APR | NAD-dependent protein deacylase sirtuin-5, mitochondrial | / | 0.472 | |
| 3ibd | CPZ | Cytochrome P450 2B6 | 1.14.13 | 0.472 | |
| 1cbs | REA | Cellular retinoic acid-binding protein 2 | / | 0.471 | |
| 1yc2 | NAD | NAD-dependent protein deacylase 2 | / | 0.471 | |
| 1zrz | BI1 | Protein kinase C iota type | 2.7.11.13 | 0.471 | |
| 2cib | CM6 | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.471 | |
| 4e4q | RRH | Peroxisome proliferator-activated receptor gamma | / | 0.471 | |
| 1cjk | FOK | Adenylate cyclase type 2 | / | 0.470 | |
| 1cjk | FOK | Adenylate cyclase type 5 | / | 0.470 | |
| 1xon | PIL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.470 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.470 | |
| 3own | 3OW | Renin | 3.4.23.15 | 0.470 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.470 | |
| 1fds | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.469 | |
| 4dym | IYZ | Activin receptor type-1 | 2.7.11.30 | 0.469 | |
| 5cp8 | TCU | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.469 | |
| 5fm7 | ADP | RuvB-like helicase | / | 0.469 | |
| 1k7f | IAV | Tryptophan synthase alpha chain | / | 0.468 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.468 | |
| 2nr4 | FMN | Conserved protein | / | 0.468 | |
| 2nsd | 4PI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.468 | |
| 4brd | ANP | Ectonucleoside triphosphate diphosphohydrolase I | / | 0.468 | |
| 4jbt | ASD | Cytochrome P450 monooxygenase | / | 0.468 | |
| 4rrx | LUR | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.468 | |
| 5e7o | MD1 | DMSO reductase family type II enzyme, molybdopterin subunit | / | 0.468 | |
| 3i8p | 840 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.467 | |
| 4i53 | 1C1 | Envelope glycoprotein gp160 | / | 0.467 | |
| 2rbe | ZMG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.466 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.466 | |
| 3w32 | W32 | Epidermal growth factor receptor | 2.7.10.1 | 0.466 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.466 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.465 | |
| 1qoq | IGP | Tryptophan synthase alpha chain | / | 0.465 | |
| 2bdy | UNB | Prothrombin | 3.4.21.5 | 0.465 | |
| 2gvd | FKP | Adenylate cyclase type 2 | / | 0.465 | |
| 2gvd | FKP | Adenylate cyclase type 5 | / | 0.465 | |
| 2zev | B71 | Geranylgeranyl pyrophosphate synthase | / | 0.465 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.465 | |
| 3r83 | Z14 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.465 | |
| 4dre | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.465 | |
| 1uml | FR4 | Adenosine deaminase | 3.5.4.4 | 0.464 | |
| 2aqb | TL6 | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.464 | |
| 2xlr | NAP | Putative flavin-containing monooxygenase | / | 0.464 | |
| 3g45 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.464 | |
| 4er6 | AW2 | Histone-lysine N-methyltransferase, H3 lysine-79 specific | 2.1.1.43 | 0.464 | |
| 3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.464 | |
| 1fml | RTL | Retinol dehydratase | / | 0.463 | |
| 1uh5 | TCL | Enoyl-ACP reductase | / | 0.463 | |
| 2kce | D16 | Thymidylate synthase | / | 0.463 | |
| 2w4q | CBW | Prostaglandin reductase 2 | 1.3.1.48 | 0.463 | |
| 3br3 | ET | HTH-type transcriptional regulator QacR | / | 0.463 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.463 | |
| 3ho2 | N32 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.463 | |
| 3m6i | NAD | L-arabinitol 4-dehydrogenase | 1.1.1.12 | 0.463 | |
| 3of2 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.463 | |
| 3qwb | NDP | Probable quinone oxidoreductase | 1.6.5.5 | 0.463 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.463 | |
| 4jaz | STL | Peroxisome proliferator-activated receptor gamma | / | 0.463 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.462 | |
| 3hub | 469 | Mitogen-activated protein kinase 14 | / | 0.462 | |
| 2w2l | NAD | D-mandelate dehydrogenase | / | 0.461 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.461 | |
| 4c71 | 7RD | 3-oxoacyl-ACP synthase | / | 0.461 | |
| 4twn | B96 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.461 | |
| 2bun | FAD | AppA protein | / | 0.460 | |
| 2cvj | FAD | Thioredoxin reductase related protein | / | 0.460 | |
| 2jh5 | 895 | Prothrombin | 3.4.21.5 | 0.460 | |
| 2vb8 | TLM | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.460 | |
| 3g11 | P9C | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.460 | |
| 4qvt | ACO | Acetyltransferase YpeA | 2.3.1 | 0.460 | |
| 4uym | VOR | 14-alpha sterol demethylase Cyp51B | / | 0.460 | |
| 3q44 | D50 | M1 family aminopeptidase | 3.4.11 | 0.459 | |
| 4e5y | NDP | GDP-L-fucose synthase | 1.1.1.271 | 0.459 | |
| 2i4z | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.458 | |
| 3bk2 | U5P | Ribonuclease J | / | 0.458 | |
| 3n8y | DIF | Prostaglandin G/H synthase 1 | 1.14.99.1 | 0.458 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.458 | |
| 4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.458 | |
| 4cax | MYA | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.458 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.458 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.457 | |
| 2aq7 | TL5 | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.457 | |
| 3vsp | EK8 | Peroxisome proliferator-activated receptor gamma | / | 0.457 | |
| 4ck2 | NVU | Integrase | / | 0.457 | |
| 4f32 | N32 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | / | 0.457 | |
| 1cs4 | FOK | Adenylate cyclase type 2 | / | 0.456 | |
| 1cs4 | FOK | Adenylate cyclase type 5 | / | 0.456 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.456 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.456 | |
| 1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.456 | |
| 2fto | CB3 | Thymidylate synthase | / | 0.456 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.456 | |
| 3r04 | UNQ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.456 | |
| 4ceq | QCH | Integrase | / | 0.456 | |
| 4i3v | NAD | Aldehyde dehydrogenase (NAD+) | / | 0.456 | |
| 4kin | 1M8 | Mitogen-activated protein kinase 14 | / | 0.456 | |
| 2zhf | 49U | Prothrombin | 3.4.21.5 | 0.455 | |
| 3c1t | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.455 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.455 | |
| 3e92 | G6A | Mitogen-activated protein kinase 14 | / | 0.455 | |
| 3iel | U5P | Ribonuclease TTHA0252 | 3.1 | 0.455 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.455 | |
| 4hs4 | FMN | Chromate reductase | / | 0.455 | |
| 4i6g | FAD | Cryptochrome-2 | / | 0.455 | |
| 4jlm | 1NN | Deoxycytidine kinase | 2.7.1.74 | 0.455 | |
| 4oxy | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.455 | |
| 1c4v | IH2 | Prothrombin | 3.4.21.5 | 0.454 | |
| 1kce | CB3 | Thymidylate synthase | / | 0.454 | |
| 1kvk | ATP | Mevalonate kinase | 2.7.1.36 | 0.454 | |
| 1vrw | NAI | Enoyl-ACP reductase | / | 0.454 | |
| 2aq8 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.454 | |
| 2bxm | IMN | Serum albumin | / | 0.454 | |
| 2j83 | BAT | Ulilysin | 3.4.24 | 0.454 | |
| 2ktd | PUC | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.454 | |
| 2om9 | AJA | Peroxisome proliferator-activated receptor gamma | / | 0.454 | |
| 2zda | 32U | Prothrombin | 3.4.21.5 | 0.454 | |
| 3f4b | TCL | Enoyl-acyl carrier protein reductase | / | 0.454 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.454 | |
| 3vy5 | FMN | FMN-binding protein | / | 0.454 | |
| 3w4y | FAD | Mitochondrial FAD-linked sulfhydryl oxidase ERV1 | 1.8.3.2 | 0.454 | |
| 3zw9 | NAD | Peroxisomal bifunctional enzyme | 1.1.1.35 | 0.454 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.454 | |
| 4cav | MYA | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.454 | |
| 1d9i | 00P | Prothrombin | 3.4.21.5 | 0.453 | |
| 1r6g | 442 | Thyroid hormone receptor beta | / | 0.453 | |
| 2rgo | FAD | Alpha-Glycerophosphate Oxidase | / | 0.453 | |
| 2yke | YKE | Heat shock protein HSP 90-alpha | / | 0.453 | |
| 3fr0 | AJB | Glucokinase | 2.7.1.2 | 0.453 | |
| 4w6z | 8ID | Alcohol dehydrogenase 1 | 1.1.1.1 | 0.453 | |
| 5c7h | NDP | Putative oxidoreductase | / | 0.453 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.452 | |
| 1jio | DEB | 6-deoxyerythronolide B hydroxylase | / | 0.452 | |
| 1vl8 | NAP | Oxidoreductase, short chain dehydrogenase/reductase family | / | 0.452 | |
| 1wsv | THH | Aminomethyltransferase, mitochondrial | / | 0.452 | |
| 2ejz | SAH | Diphthine synthase | / | 0.452 | |
| 2rg5 | 279 | Mitogen-activated protein kinase 14 | / | 0.452 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.452 | |
| 3aos | JH2 | Hemolymph juvenile hormone binding protein | / | 0.452 | |
| 3i59 | N6S | CRP-like cAMP-activated global transcriptional regulator | / | 0.452 | |
| 3vtb | TKA | Vitamin D3 receptor | / | 0.452 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 4r81 | FMN | Predicted NADH dehydrogenase | / | 0.452 | |
| 5hwr | COA | Hydroxymethylglutaryl-CoA synthase | / | 0.452 | |
| 1d3d | BZT | Prothrombin | 3.4.21.5 | 0.451 | |
| 1ndh | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.451 | |
| 1nq1 | 4HY | Thyroid hormone receptor beta | / | 0.451 | |
| 1w7k | ADP | Dihydrofolate synthase/folylpolyglutamate synthase | 6.3.2.12 | 0.451 | |
| 2aqh | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.451 | |
| 2q2q | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.451 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.451 | |
| 4dz5 | NAP | Aldo-keto reductase family 1 member C3 | / | 0.451 | |
| 4g67 | SAH | Uncharacterized ACR, COG1565 superfamily | / | 0.451 | |
| 4hhz | 15S | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.451 | |
| 5hs1 | VOR | Lanosterol 14-alpha demethylase | / | 0.451 | |
| 5kgh | ACO | Predicted acetyltransferase | / | 0.451 | |
| 1eio | GCH | Gastrotropin | / | 0.450 | |
| 1ib0 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.450 | |
| 1s1p | NAP | Aldo-keto reductase family 1 member C3 | / | 0.450 | |
| 1v35 | NAI | Enoyl-ACP reductase | / | 0.450 | |
| 2fap | RAD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.450 | |
| 2fap | RAD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.450 | |
| 2h2q | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.450 | |
| 2nq8 | ZID | Enoyl-ACP reductase | / | 0.450 | |
| 2zhq | 27U | Prothrombin | 3.4.21.5 | 0.450 | |
| 3af2 | ACP | Pantothenate kinase | 2.7.1.33 | 0.450 | |
| 3huc | G97 | Mitogen-activated protein kinase 14 | / | 0.450 | |
| 3mqe | 416 | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.450 | |
| 3nx4 | NAP | Putative oxidoreductase | / | 0.450 | |
| 3oey | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.450 | |
| 4c72 | TLG | 3-oxoacyl-ACP synthase | / | 0.450 | |
| 4i4b | 1CV | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.88 | 0.450 | |
| 4i54 | 1C1 | Envelope glycoprotein gp160 | / | 0.450 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.450 | |
| 4pmj | NAP | Putative oxidoreductase | / | 0.450 | |
| 4zju | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.450 | |
| 1cjt | FOK | Adenylate cyclase type 2 | / | 0.449 | |
| 1cjt | FOK | Adenylate cyclase type 5 | / | 0.449 | |
| 1e3e | NAI | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.449 | |
| 1gqt | ACP | Ribokinase | / | 0.449 | |
| 1h69 | ARH | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.449 | |
| 1kc1 | NDP | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.449 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.449 | |
| 2iod | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.449 | |
| 2ojg | 19A | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.449 | |
| 2q2v | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.449 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.449 | |
| 2xjj | L81 | Heat shock protein HSP 90-alpha | / | 0.449 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.449 | |
| 4xq9 | NAD | Homospermidine synthase | 2.5.1.44 | 0.449 | |
| 1trg | CB3 | Thymidylate synthase | / | 0.448 | |
| 1v4s | MRK | Glucokinase | 2.7.1.2 | 0.448 | |
| 2bac | FAD | Putative aminooxidase | / | 0.448 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.448 | |
| 2zlc | VDX | Vitamin D3 receptor | / | 0.448 | |
| 3anm | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.448 | |
| 3g70 | A5T | Renin | 3.4.23.15 | 0.448 | |
| 3gfy | FMN | Uncharacterized protein | / | 0.448 | |
| 3u5s | FAD | FAD-linked sulfhydryl oxidase ALR | 1.8.3.2 | 0.448 | |
| 4a2z | VIQ | Glycylpeptide N-tetradecanoyltransferase | / | 0.448 | |
| 4cax | 646 | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.448 | |
| 4cjs | L0Y | Integrase | / | 0.448 | |
| 4e0i | FAD | Mitochondrial FAD-linked sulfhydryl oxidase ERV1 | 1.8.3.2 | 0.448 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.448 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.448 | |
| 1fwy | UD1 | Bifunctional protein GlmU | / | 0.447 | |
| 1w83 | L11 | Mitogen-activated protein kinase 14 | / | 0.447 | |
| 1zg3 | 2HI | Isoflavone 4'-O-methyltransferase | / | 0.447 | |
| 1zsn | TN2 | Enoyl-ACP reductase | / | 0.447 | |
| 2bel | CBO | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.447 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.447 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.447 | |
| 2owu | SAH | Diphthine synthase | / | 0.447 | |
| 2xvi | FAD | Putative flavin-containing monooxygenase | / | 0.447 | |
| 3b9l | AZZ | Serum albumin | / | 0.447 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.447 | |
| 3gmd | 2M3 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.447 | |
| 3iae | D7K | Benzaldehyde lyase | / | 0.447 | |
| 3jyn | NDP | Quinone oxidoreductase | / | 0.447 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.447 | |
| 4ead | 0NP | Thymidine phosphorylase | 2.4.2.4 | 0.447 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.447 | |
| 3qak | UKA | Adenosine receptor A2a | / | 0.447 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1e7a | PFL | Serum albumin | / | 0.446 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 1i5a | ACP | Chemotaxis protein CheA | 2.7.13.3 | 0.446 | |
| 1kqw | RTL | Cellular retinol-binding protein type II | / | 0.446 | |
| 1uuo | BRF | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.446 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 1ykd | CMP | Adenylate cyclase | / | 0.446 | |
| 2b4t | AES | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.446 | |
| 2fzm | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.446 | |
| 2gev | COK | Pantothenate kinase | 2.7.1.33 | 0.446 | |
| 2j07 | HDF | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.446 | |
| 2j5x | GSP | ADP-ribosylation factor 6 | / | 0.446 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial | 1.2.4.4 | 0.446 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial | 1.2.4.4 | 0.446 | |
| 2vqb | NAP | Putative flavin-containing monooxygenase | / | 0.446 | |
| 2w6n | OA2 | Biotin carboxylase | 6.3.4.14 | 0.446 | |
| 3fql | 79Z | Genome polyprotein | 2.7.7.48 | 0.446 | |
| 3inx | JZC | Heat shock protein HSP 90-alpha | / | 0.446 | |
| 3p9t | TCL | Repressor | / | 0.446 | |
| 3pm1 | ET | HTH-type transcriptional regulator QacR | / | 0.446 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.446 | |
| 3uic | 09T | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.446 | |
| 3vev | 0H4 | Glucokinase | 2.7.1.2 | 0.446 | |
| 3w78 | CBD | FMN-dependent NADH-azoreductase | / | 0.446 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.446 | |
| 1eny | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.445 | |
| 1f4f | TP3 | Thymidylate synthase | / | 0.445 | |
| 1fnd | A2P | Ferredoxin--NADP reductase, chloroplastic | 1.18.1.2 | 0.445 | |
| 1uyc | PU7 | Heat shock protein HSP 90-alpha | / | 0.445 | |
| 1ydt | IQB | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.445 | |
| 2anm | CDO | Prothrombin | 3.4.21.5 | 0.445 | |
| 2e94 | 364 | Geranylgeranyl pyrophosphate synthase | / | 0.445 | |
| 2gfx | PMN | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.445 | |
| 2zc9 | 22U | Prothrombin | 3.4.21.5 | 0.445 | |
| 3id8 | MRK | Glucokinase | 2.7.1.2 | 0.445 | |
| 3oew | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.445 | |
| 4a95 | 9MT | Glycylpeptide N-tetradecanoyltransferase | / | 0.445 | |
| 4bms | NAP | Alclohol dehydrogenase/short-chain dehydrogenase | / | 0.445 | |
| 4ge4 | 0KE | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.445 | |
| 4jv8 | 1M1 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.445 | |
| 4oty | LUR | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.445 | |
| 4xqc | NAD | Homospermidine synthase | 2.5.1.44 | 0.445 | |
| 5kf9 | ACO | Predicted acetyltransferase | / | 0.445 | |
| 5kgj | ACO | Predicted acetyltransferase | / | 0.445 | |
| 1gzu | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.444 | |
| 1iyz | NDP | Probable quinone oxidoreductase | / | 0.444 | |
| 1ma0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.444 | |
| 1p0h | COA | Mycothiol acetyltransferase | 2.3.1.189 | 0.444 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.444 | |
| 2i4p | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.444 | |
| 2ji9 | TPW | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.444 | |
| 2uxu | NAR | HTH-type transcriptional regulator TtgR | / | 0.444 | |
| 2xvf | FAD | Putative flavin-containing monooxygenase | / | 0.444 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.444 | |
| 3cop | ADP | Glycogen synthase | 2.4.1.21 | 0.444 | |
| 4e2d | FMN | Dehydrogenase | / | 0.444 | |
| 4f6w | 0SS | Cyclin-dependent kinase 8 | 2.7.11.22 | 0.444 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.444 | |
| 4q72 | FAD | Bifunctional protein PutA | / | 0.444 | |
| 4xo7 | NAP | Aldo-keto reductase family 1 member C2 | / | 0.444 | |
| 1bvr | THT | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 1nsg | RAD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.443 | |
| 1nsg | RAD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.443 | |
| 1o5r | FR9 | Adenosine deaminase | 3.5.4.4 | 0.443 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 1r37 | NAD | NAD-dependent alcohol dehydrogenase | 1.1.1.1 | 0.443 | |
| 1yhj | R6C | Pyridoxal kinase | 2.7.1.35 | 0.443 | |
| 2bxq | IMN | Serum albumin | / | 0.443 | |
| 2q5p | 241 | Peroxisome proliferator-activated receptor gamma | / | 0.443 | |
| 2tsc | CB3 | Thymidylate synthase | / | 0.443 | |
| 2xvv | 9DN | Serum albumin | / | 0.443 | |
| 2ydo | ADN | Adenosine receptor A2a | / | 0.443 | |
| 2ziq | 26U | Prothrombin | 3.4.21.5 | 0.443 | |
| 2zsd | COA | Pantothenate kinase | 2.7.1.33 | 0.443 | |
| 3bi2 | FAD | Polyamine oxidase FMS1 | / | 0.443 | |
| 3hat | GLY_VAL_ARG_RNG | Prothrombin | 3.4.21.5 | 0.443 | |
| 3hyg | 099 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.443 | |
| 3iw1 | ASD | Steroid C26-monooxygenase | 1.14.13.141 | 0.443 | |
| 3oqf | S51 | Renin | 3.4.23.15 | 0.443 | |
| 3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.443 | |
| 3q7d | NPX | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.443 | |
| 3w2e | NAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.443 | |
| 4a30 | QMI | Glycylpeptide N-tetradecanoyltransferase | / | 0.443 | |
| 4i8v | BHF | Cytochrome P450 1A1 | 1.14.14.1 | 0.443 | |
| 4jlj | 1NM | Deoxycytidine kinase | 2.7.1.74 | 0.443 | |
| 4kwh | NAP | Reductase homolog | / | 0.443 | |
| 4pl0 | ANP | Microcin-J25 export ATP-binding/permease protein McjD | / | 0.443 | |
| 4ybn | FAD | Flavin-nucleotide-binding protein | / | 0.443 | |
| 4zm6 | ACO | N-acetyl-beta-D glucosaminidase | / | 0.443 | |
| 5akk | 1P8 | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.443 | |
| 5bn3 | ADP | V-type ATP synthase alpha chain | / | 0.443 | |
| 5bn3 | ADP | NEQ263 | / | 0.443 | |
| 5hwq | CAA | Hydroxymethylglutaryl-CoA synthase | / | 0.443 | |
| 3eml | ZMA | Adenosine receptor A2a | / | 0.443 | |
| 1dkf | BMS | Retinoic acid receptor alpha | / | 0.442 | |
| 1f20 | FAD | Nitric oxide synthase, brain | 1.14.13.39 | 0.442 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.442 | |
| 1ndz | FR5 | Adenosine deaminase | 3.5.4.4 | 0.442 | |
| 1qy5 | NEC | Endoplasmin | / | 0.442 | |
| 2c59 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.442 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.442 | |
| 2g1o | 2IG | Renin | 3.4.23.15 | 0.442 | |
| 2i4q | UA4 | Renin | 3.4.23.15 | 0.442 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.442 | |
| 3bhr | THG | Thymidylate synthase | / | 0.442 | |
| 3e8x | NAP | BH1520 protein | / | 0.442 | |
| 3l9n | L9N | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.442 | |
| 3mpt | 1GK | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.442 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 4ce9 | O3N | Integrase | / | 0.442 | |
| 4gt3 | ATP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.442 | |
| 4gxs | 0YS | Glutamate receptor 2 | / | 0.442 | |
| 4jic | FMN | GTN Reductase | / | 0.442 | |
| 1fdu | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.441 | |
| 1ffu | FAD | Carbon monoxide dehydrogenase medium chain | / | 0.441 | |
| 1kzj | CB3 | Thymidylate synthase | / | 0.441 | |
| 1qvu | PRL | HTH-type transcriptional regulator QacR | / | 0.441 | |
| 1tys | DHF | Thymidylate synthase | / | 0.441 | |
| 1zgy | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.441 | |
| 2h9i | EAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 2ntj | P1H | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 2r1r | TTP | Ribonucleoside-diphosphate reductase 1 subunit alpha | 1.17.4.1 | 0.441 | |
| 2rc6 | NAP | Ferredoxin--NADP reductase | / | 0.441 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.441 | |
| 2zb3 | NDP | Prostaglandin reductase 2 | 1.3.1.48 | 0.441 | |
| 3bw4 | FMN | Putative 2-nitropropane dioxygenase | / | 0.441 | |
| 3cos | NAD | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.441 | |
| 3d5q | T30 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.441 | |
| 3dop | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.441 | |
| 3kc0 | 2T5 | Fructose-1,6-bisphosphatase 1 | 3.1.3.11 | 0.441 | |
| 3pe2 | E1B | Casein kinase II subunit alpha | 2.7.11.1 | 0.441 | |
| 4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.441 | |
| 4cif | JDX | Integrase | / | 0.441 | |
| 4eag | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.441 | |
| 4is3 | NAD | 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 2 | 1.17.98.1 | 0.441 | |
| 4jlk | 1NO | Deoxycytidine kinase | 2.7.1.74 | 0.441 | |
| 4m6p | 20R | Nicotinamide phosphoribosyltransferase | 2.4.2.12 | 0.441 | |
| 4phl | PIL | Phosphodiesterase | / | 0.441 | |
| 4rrw | LUR | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.441 | |
| 4rrz | LUR | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.441 | |
| 4xuh | SFI | Peroxisome proliferator-activated receptor gamma | / | 0.441 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.440 | |
| 1p91 | SAM | 23S rRNA (guanine(745)-N(1))-methyltransferase | / | 0.440 | |
| 2a9z | 26A | Adenosine kinase | 2.7.1.20 | 0.440 | |
| 2ekp | NAD | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.440 | |
| 2h21 | SAM | Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic | 2.1.1.127 | 0.440 | |
| 2h55 | DZ8 | Heat shock protein HSP 90-alpha | / | 0.440 | |
| 2prz | OMP | Orotate phosphoribosyltransferase 1 | 2.4.2.10 | 0.440 | |
| 2qo6 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.440 | |
| 2r2n | KYN | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.440 | |
| 2w6q | OA5 | Biotin carboxylase | 6.3.4.14 | 0.440 | |
| 3a3y | OBN | Sodium/potassium-transporting ATPase subunit alpha | / | 0.440 | |
| 3cxw | 7CP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.440 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.440 | |
| 3hnz | PMN | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.440 | |
| 3pyz | ANP | Dihydrofolate synthase/folylpolyglutamate synthase | / | 0.440 | |
| 4an4 | DUD | Putative glycosyl transferase | / | 0.440 | |
| 4e0h | FAD | Mitochondrial FAD-linked sulfhydryl oxidase ERV1 | 1.8.3.2 | 0.440 | |
| 4z28 | BTN | Hoefavidin | / | 0.440 | |
| 5h8t | RTL | Retinol-binding protein 1 | / | 0.440 |