sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4ajm | 3A6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4ajm | 3A6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 1.000 | |
| 4ajf | F03 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.678 | |
| 4fcb | 0T7 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.667 | |
| 2wey | EV1 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.665 | |
| 3wi2 | P98 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.656 | |
| 2ovv | PFH | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.643 | |
| 4lm4 | JPZ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.642 | |
| 4llk | MEW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.638 | |
| 2y0j | AXC | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.636 | |
| 3qpo | PFR | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.636 | |
| 2o8h | 227 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.632 | |
| 3sni | 546 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.632 | |
| 1y2b | DEE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.629 | |
| 4ddl | 0JQ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.629 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.615 | |
| 4hf4 | 15H | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.615 | |
| 4ajd | F04 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.613 | |
| 3g4i | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.609 | |
| 4ajg | F07 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.606 | |
| 1q9m | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.605 | |
| 2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.604 | |
| 2ovy | PFJ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.604 | |
| 4fcd | 0T6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.604 | |
| 2ouy | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.603 | |
| 3sn7 | 540 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.598 | |
| 4muw | 2F4 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.597 | |
| 3g4k | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.593 | |
| 3sl6 | JN8 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.587 | |
| 1zkn | IBM | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.585 | |
| 3tvx | PNX | cAMP-specific 3',5'-cyclic phosphodiesterase 4A | 3.1.4.53 | 0.581 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.581 | |
| 1soj | IBM | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.580 | |
| 2h44 | 7CA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.580 | |
| 1uho | VDN | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.579 | |
| 1ro6 | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.575 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.571 | |
| 1xor | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.570 | |
| 1y2e | 5DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.569 | |
| 3g58 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.568 | |
| 3itu | IBM | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.566 | |
| 3wd9 | QPC | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.564 | |
| 3sl8 | JN7 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.560 | |
| 1y2d | 4DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.558 | |
| 2fm0 | M98 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.558 | |
| 1oyn | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.556 | |
| 4bbx | LKF | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.556 | |
| 1ro9 | 8BR | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.554 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.553 | |
| 1xoq | ROF | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.553 | |
| 3o56 | ZG1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.551 | |
| 1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.550 | |
| 2h42 | VIA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.550 | |
| 3w5e | NVW | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.550 | |
| 4phl | PIL | Phosphodiesterase | / | 0.550 | |
| 4c1i | EH9 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.549 | |
| 1y2k | 7DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.548 | |
| 3d3p | 20A | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.547 | |
| 4jib | 1L6 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.547 | |
| 4g2y | NI5 | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.545 | |
| 1tbb | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.544 | |
| 3g4l | ROF | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.544 | |
| 4oew | 5IO | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.544 | |
| 3iak | EV1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.541 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.539 | |
| 1rkp | IBM | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.538 | |
| 3o57 | ZG2 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.537 | |
| 3g4g | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.536 | |
| 1so2 | 666 | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.535 | |
| 3k4s | 0MO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.531 | |
| 4g2w | NI0 | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.531 | |
| 3bjc | WAN | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.529 | |
| 1xon | PIL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.528 | |
| 1y2c | 3DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.527 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.525 | |
| 4i9z | 5BA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.522 | |
| 3g45 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.521 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.519 | |
| 3v94 | WYQ | Phosphodiesterase | / | 0.516 | |
| 4oex | 5EO | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.515 | |
| 1udt | VIA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.514 | |
| 3hmv | HBT | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.514 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.508 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.503 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.502 | |
| 2on6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.500 | |
| 3a1l | 2CC | Cytochrome P450 | / | 0.497 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.497 | |
| 1zkl | IBM | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | 3.1.4.53 | 0.496 | |
| 2bf7 | HBI | Pteridine reductase 1 | 1.5.1.33 | 0.496 | |
| 4myq | 19T | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.495 | |
| 2z7g | EH9 | Adenosine deaminase | 3.5.4.4 | 0.494 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.493 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.492 | |
| 2toh | HBI | Tyrosine 3-monooxygenase | 1.14.16.2 | 0.490 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.490 | |
| 5dp2 | NAP | CurF | / | 0.490 | |
| 4ia0 | 5BB | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.489 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.488 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.487 | |
| 1oj4 | CDM | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | 2.7.1.148 | 0.486 | |
| 2pl0 | STI | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.485 | |
| 4rbs | 0RV | Metallo-beta-lactamase type 2 | / | 0.485 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.484 | |
| 5iu8 | 6DZ | Adenosine receptor A2a | / | 0.484 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.483 | |
| 5k2c | ZMA | Adenosine receptor A2a | / | 0.483 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.482 | |
| 2yne | YNE | Glycylpeptide N-tetradecanoyltransferase | / | 0.482 | |
| 3nrr | D16 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.482 | |
| 3up0 | D7S | aceDAF-12 | / | 0.482 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.481 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.481 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.480 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.480 | |
| 3c1t | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.479 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.479 | |
| 3s3v | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.479 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.478 | |
| 3up3 | XCA | aceDAF-12 | / | 0.478 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.478 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.477 | |
| 2v2z | CDM | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.477 | |
| 1p8d | CO1 | Oxysterols receptor LXR-beta | / | 0.476 | |
| 1wsv | THH | Aminomethyltransferase, mitochondrial | / | 0.476 | |
| 2w4q | CBW | Prostaglandin reductase 2 | 1.3.1.48 | 0.476 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.474 | |
| 1rt9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.474 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.474 | |
| 4bjc | RPB | Tankyrase-2 | 2.4.2.30 | 0.474 | |
| 4kfj | 1R0 | Dihydrofolate reductase | 1.5.1.3 | 0.474 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.473 | |
| 1clq | GDP | DNA-directed DNA polymerase | / | 0.473 | |
| 3njo | PYV | Abscisic acid receptor PYR1 | / | 0.473 | |
| 3nx2 | FER | Ferulic acid decarboxylase | / | 0.473 | |
| 4kak | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.473 | |
| 5iub | CLR | Adenosine receptor A2a | / | 0.473 | |
| 5k2b | ZMA | Adenosine receptor A2a | / | 0.473 | |
| 1ndy | FR3 | Adenosine deaminase | 3.5.4.4 | 0.472 | |
| 1uml | FR4 | Adenosine deaminase | 3.5.4.4 | 0.472 | |
| 2iod | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.472 | |
| 3hbf | MYC | Flavonoid 3-O-glucosyltransferase | 2.4.1 | 0.472 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.472 | |
| 1eno | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic | 1.3.1.9 | 0.471 | |
| 4b65 | NDP | L-ornithine N(5)-monooxygenase | / | 0.471 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.471 | |
| 5fm7 | ADP | RuvB-like helicase | / | 0.471 | |
| 1eji | THF | Serine hydroxymethyltransferase, cytosolic | / | 0.470 | |
| 1ndz | FR5 | Adenosine deaminase | 3.5.4.4 | 0.470 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.470 | |
| 1rr6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.470 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.470 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.470 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.470 | |
| 4wev | SUZ | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.470 | |
| 5iua | 6DX | Adenosine receptor A2a | / | 0.470 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.469 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.469 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.469 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.469 | |
| 4u7w | NDP | MxaA | / | 0.469 | |
| 1g63 | FMN | Epidermin decarboxylase | 4.1.1 | 0.468 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.468 | |
| 2ejz | SAH | Diphthine synthase | / | 0.468 | |
| 2xvi | FAD | Putative flavin-containing monooxygenase | / | 0.468 | |
| 4lxj | LAN | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.468 | |
| 4tx9 | AMZ | Phosphoribosyl isomerase A | / | 0.468 | |
| 5iu4 | ZMA | Adenosine receptor A2a | / | 0.468 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.467 | |
| 2a0x | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.467 | |
| 2bjs | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.467 | |
| 2v58 | LZJ | Biotin carboxylase | 6.3.4.14 | 0.467 | |
| 2v5u | FMN | Flavodoxin | / | 0.467 | |
| 4ckr | DI1 | Epithelial discoidin domain-containing receptor 1 | 2.7.10.1 | 0.467 | |
| 4frk | DWD | Beta-secretase 1 | 3.4.23.46 | 0.467 | |
| 1lke | DOG | Bilin-binding protein | / | 0.466 | |
| 1s3w | TQT | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
| 1zq5 | E04 | Aldo-keto reductase family 1 member C3 | / | 0.466 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.466 | |
| 3ntz | 3TZ | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.465 | |
| 1upw | 444 | Oxysterols receptor LXR-beta | / | 0.465 | |
| 1xf0 | ASD | Aldo-keto reductase family 1 member C3 | / | 0.465 | |
| 2cbq | TH2 | Neocarzinostatin | / | 0.465 | |
| 2fzb | TOL | Aldose reductase | 1.1.1.21 | 0.465 | |
| 4bew | ACP | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.465 | |
| 4bmp | FMN | Protein NrdI | / | 0.465 | |
| 4gll | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.465 | |
| 4heu | 15J | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.465 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 1icq | OPD | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.464 | |
| 1sd2 | MTH | S-methyl-5'-thioadenosine phosphorylase | / | 0.464 | |
| 2rl5 | 2RL | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.464 | |
| 4a95 | 9MT | Glycylpeptide N-tetradecanoyltransferase | / | 0.464 | |
| 4imf | SI3 | N-acetylneuraminate lyase | / | 0.464 | |
| 5k2a | ZMA | Adenosine receptor A2a | / | 0.464 | |
| 1h22 | E10 | Acetylcholinesterase | 3.1.1.7 | 0.463 | |
| 3u9f | CLM | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.463 | |
| 4g1y | 0VO | Vitamin D3 receptor A | / | 0.463 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.462 | |
| 1rxj | BNI | Streptavidin | / | 0.462 | |
| 3ghw | GHW | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 3lnb | COA | N-acetyltransferase family protein | / | 0.462 | |
| 3qi4 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.462 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.462 | |
| 1e2n | RCA | Thymidine kinase | / | 0.461 | |
| 1rsz | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.461 | |
| 2ym2 | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.461 | |
| 3bxx | QUE | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.461 | |
| 3pah | XDE | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.461 | |
| 1i05 | LTL | Major urinary protein 6 | / | 0.460 | |
| 2f98 | NGV | Aklanonic acid methyl ester cyclase AcmA | 5.5.1.23 | 0.460 | |
| 2oci | TYC | Valacyclovir hydrolase | 3.1 | 0.460 | |
| 3d4b | DZD | NAD-dependent protein deacetylase | / | 0.460 | |
| 3l3r | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.460 | |
| 3qeo | LLT | Deoxycytidine kinase | 2.7.1.74 | 0.460 | |
| 4mvh | 2F5 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.460 | |
| 5dn1 | AMZ | Phosphoribosyl isomerase A | 5.3.1.16 | 0.460 | |
| 5g53 | NEC | Adenosine receptor A2a | / | 0.460 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 1v7a | FRC | Adenosine deaminase | 3.5.4.4 | 0.459 | |
| 2jbs | FMN | p-hydroxyphenylacetate 3-hydroxylase, oxygenase component | / | 0.459 | |
| 3g49 | 3G4 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.459 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.459 | |
| 5epv | ACP | Blue-light-activated histidine kinase | 2.7.13.3 | 0.459 | |
| 1fml | RTL | Retinol dehydratase | / | 0.458 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 2fb8 | 215 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.458 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.458 | |
| 3nxo | D2B | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 4d03 | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.458 | |
| 4d04 | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.458 | |
| 4emd | C5P | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.458 | |
| 4jq4 | IMN | Aldo-keto reductase family 1 member C2 | / | 0.458 | |
| 4jqh | 1MF | Alr2278 protein | / | 0.458 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.457 | |
| 1wxy | FRK | Adenosine deaminase | 3.5.4.4 | 0.457 | |
| 2ix5 | FAD | Acyl-coenzyme A oxidase 4, peroxisomal | 1.3.3.6 | 0.457 | |
| 2xkd | T3M | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.457 | |
| 3k47 | D09 | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 4dk7 | 0KS | Oxysterols receptor LXR-beta | / | 0.457 | |
| 4ge4 | 0KE | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.457 | |
| 5uvi | ZMA | Adenosine receptor A2a | / | 0.457 | |
| 3eml | ZMA | Adenosine receptor A2a | / | 0.457 | |
| 1nbi | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.456 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 2z7h | GG3 | Geranylgeranyl pyrophosphate synthase | / | 0.456 | |
| 3fgo | ACP | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.456 | |
| 3jyo | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.456 | |
| 4b2g | V1N | Uncharacterized protein | / | 0.456 | |
| 4eqr | COA | Coenzyme A disulfide reductase | / | 0.456 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.456 | |
| 5bt4 | 2LO | Bromodomain-containing protein 4 | / | 0.456 | |
| 1boz | PRD | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 1rkh | VD2 | Vitamin D3 receptor | / | 0.455 | |
| 3c3d | FO1 | 2-phospho-L-lactate transferase | / | 0.455 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.455 | |
| 4twn | B96 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.455 | |
| 2bfm | TOP | Pteridine reductase 1 | 1.5.1.33 | 0.454 | |
| 2pup | ADP | Methylthioribose kinase | 2.7.1.100 | 0.454 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.454 | |
| 2x0e | TYD | WsaF | / | 0.454 | |
| 3aos | JH2 | Hemolymph juvenile hormone binding protein | / | 0.454 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.454 | |
| 4few | PP2 | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.454 | |
| 4gt8 | ADP | Sensor protein VraS | 2.7.13.3 | 0.454 | |
| 4uof | DAT | Nucleoside diphosphate kinase | / | 0.454 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.453 | |
| 1re0 | AFB | ADP-ribosylation factor 1 | / | 0.453 | |
| 1re0 | AFB | ARF guanine-nucleotide exchange factor 1 | / | 0.453 | |
| 1xh5 | R68 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.453 | |
| 1zua | TOL | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.453 | |
| 2fzd | TOL | Aldose reductase | 1.1.1.21 | 0.453 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.453 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 2pnu | ENM | Androgen receptor | / | 0.453 | |
| 2v8p | CDP | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.453 | |
| 2zi5 | 3L1 | Deoxycytidine kinase | 2.7.1.74 | 0.453 | |
| 3kpz | ZNE | Vitamin D3 receptor | / | 0.453 | |
| 3sqx | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.453 | |
| 4blc | NDP | Catalase | 1.11.1.6 | 0.453 | |
| 4c77 | N01 | Phenylacetone monooxygenase | 1.14.13.92 | 0.453 | |
| 4wx2 | F6F | Tryptophan synthase alpha chain | / | 0.453 | |
| 4wx2 | F6F | Tryptophan synthase beta chain | 4.2.1.20 | 0.453 | |
| 1buc | FAD | Acyl-CoA dehydrogenase, short-chain specific | 1.3.8.1 | 0.452 | |
| 1q0r | AKT | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.452 | |
| 1qti | GNT | Acetylcholinesterase | 3.1.1.7 | 0.452 | |
| 2g27 | 4LG | Renin | 3.4.23.15 | 0.452 | |
| 2nnq | T4B | Fatty acid-binding protein, adipocyte | / | 0.452 | |
| 2z1q | FAD | Acyl-CoA dehydrogenase | / | 0.452 | |
| 3dl9 | V2H | Vitamin D 25-hydroxylase | / | 0.452 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.452 | |
| 1ie9 | VDX | Vitamin D3 receptor | / | 0.451 | |
| 2fa3 | ACO | Hydroxymethylglutaryl-CoA synthase | / | 0.451 | |
| 2g1a | 5HG | Class B acid phosphatase | 3.1.3.2 | 0.451 | |
| 3aiq | HBO | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1b, chloroplastic | 3.2.1.182 | 0.451 | |
| 3aiv | HBO | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase, chloroplastic | 3.2.1.182 | 0.451 | |
| 3ch6 | 311 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.451 | |
| 3fp0 | FP0 | 15-O-acetyltransferase | / | 0.451 | |
| 3hxd | BD7 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.451 | |
| 4kw5 | 1W6 | Decaprenylphosphoryl-beta-D-ribose oxidase | / | 0.451 | |
| 1c7o | PPG | Hemolysin | / | 0.450 | |
| 1el4 | CTZ | Obelin | / | 0.450 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 2vqq | TFG | Histone deacetylase 4 | 3.5.1.98 | 0.450 | |
| 2zi6 | 3D1 | Deoxycytidine kinase | 2.7.1.74 | 0.450 | |
| 3fr2 | 8CA | Fatty acid-binding protein, adipocyte | / | 0.450 | |
| 3h4v | DVP | Pteridine reductase 1 | 1.5.1.33 | 0.450 | |
| 3nxv | D2F | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 3zc3 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.450 | |
| 4fhd | 0TT | Spore photoproduct lyase | / | 0.450 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.450 | |
| 5k2d | ZMA | Adenosine receptor A2a | / | 0.450 | |
| 1ao8 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1dgb | NDP | Catalase | 1.11.1.6 | 0.449 | |
| 1v79 | FR7 | Adenosine deaminase | 3.5.4.4 | 0.449 | |
| 1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.449 | |
| 1yc2 | NAD | NAD-dependent protein deacylase 2 | / | 0.449 | |
| 2f38 | 15M | Aldo-keto reductase family 1 member C3 | / | 0.449 | |
| 2fjm | 073 | Tyrosine-protein phosphatase non-receptor type 1 | 3.1.3.48 | 0.449 | |
| 2w6c | BM4 | Acetylcholinesterase | 3.1.1.7 | 0.449 | |
| 2xkf | BX1 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.449 | |
| 2xlt | NA0 | Putative flavin-containing monooxygenase | / | 0.449 | |
| 2ydv | NEC | Adenosine receptor A2a | / | 0.449 | |
| 2z3u | CRR | Cytochrome P450 | / | 0.449 | |
| 3d5q | T30 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.449 | |
| 3hf6 | LX0 | Tryptophan 5-hydroxylase 1 | 1.14.16.4 | 0.449 | |
| 3tdk | UPG | UDP-glucose 6-dehydrogenase | 1.1.1.22 | 0.449 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.449 | |
| 4b67 | NAP | L-ornithine N(5)-monooxygenase | / | 0.449 | |
| 4dbs | 0HV | Aldo-keto reductase family 1 member C3 | / | 0.449 | |
| 4ead | 0NP | Thymidine phosphorylase | 2.4.2.4 | 0.449 | |
| 4uug | PXG | Branched-chain amino acid aminotransferase, putative | / | 0.449 | |
| 1ohj | COP | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1v3q | 2DI | Purine nucleoside phosphorylase | 2.4.2.1 | 0.448 | |
| 1zg3 | 2HI | Isoflavone 4'-O-methyltransferase | / | 0.448 | |
| 2hc4 | VDX | Vitamin D3 receptor A | / | 0.448 | |
| 2ipj | FFA | Aldo-keto reductase family 1 member C2 | / | 0.448 | |
| 2ym1 | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.448 | |
| 3djf | BC3 | Purine nucleoside phosphorylase | / | 0.448 | |
| 3gie | ACP | Sensor histidine kinase DesK | 2.7.13.3 | 0.448 | |
| 3hv3 | R49 | Mitogen-activated protein kinase 14 | / | 0.448 | |
| 3jsx | CC2 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.448 | |
| 3n0h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.448 | |
| 3uyk | 0CX | Probable NDP-rhamnosyltransferase | / | 0.448 | |
| 4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.448 | |
| 4bbh | YBN | Glycylpeptide N-tetradecanoyltransferase | / | 0.448 | |
| 4bj9 | UHB | Tankyrase-2 | 2.4.2.30 | 0.448 | |
| 4dbw | 511 | Aldo-keto reductase family 1 member C3 | / | 0.448 | |
| 4dym | IYZ | Activin receptor type-1 | 2.7.11.30 | 0.448 | |
| 4ia1 | BIV | Vitamin D3 receptor A | / | 0.448 | |
| 4l1x | STR | Aldo-keto reductase family 1 member C2 | / | 0.448 | |
| 1crb | RTL | Retinol-binding protein 1 | / | 0.447 | |
| 1fkx | PRH | Adenosine deaminase | 3.5.4.4 | 0.447 | |
| 1kms | LIH | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1sjw | NGV | Nogalonic acid methyl ester cyclase | / | 0.447 | |
| 2dhf | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 2r6j | NDP | Eugenol synthase 1 | 1.1.1.318 | 0.447 | |
| 2uag | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.447 | |
| 2wgs | 1AZ | Glutamine synthetase | 6.3.1.2 | 0.447 | |
| 3ewk | FAD | Sensory box histidine kinase/response regulator | / | 0.447 | |
| 3qv1 | NAD | Glyceraldehyde-3-phosphate dehydrogenase GAPA1, chloroplastic | 1.2.1.13 | 0.447 | |
| 3t0k | DCQ | Sulfide-quinone reductase | / | 0.447 | |
| 4k4e | K4E | Tankyrase-1 | 2.4.2.30 | 0.447 | |
| 1q23 | FUA | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.446 | |
| 1q6p | 213 | Tyrosine-protein phosphatase non-receptor type 1 | 3.1.3.48 | 0.446 | |
| 2fzj | DH3 | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.446 | |
| 3ar4 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.446 | |
| 3c0g | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.446 | |
| 3f6s | FMN | Flavodoxin | / | 0.446 | |
| 3nxr | D2D | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 3vg9 | ZMA | Adenosine receptor A2a | / | 0.446 | |
| 3wav | DWV | Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 | 3.1.4.39 | 0.446 | |
| 4h3f | 10O | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 4rtr | SAM | DNA adenine methylase | 2.1.1.72 | 0.446 | |
| 4xo7 | ASD | Aldo-keto reductase family 1 member C2 | / | 0.446 | |
| 4zas | TYD | CalS13 | / | 0.446 | |
| 5hbr | COA | Acyl-CoA synthetase (NDP forming) | / | 0.446 | |
| 1h66 | RH1 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.445 | |
| 1kmv | LII | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 2i65 | NAD | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.445 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.445 | |
| 3hwx | TPP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.445 | |
| 3nyt | ULP | UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase | 2.6.1.98 | 0.445 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 4cvm | ANP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.445 | |
| 4eiy | ZMA | Adenosine receptor A2a | / | 0.445 | |
| 4kd7 | 9DR | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 4n82 | FMN | Ribonucleotide reductase (NrdI family protein), putative | / | 0.445 | |
| 5hwq | CAA | Hydroxymethylglutaryl-CoA synthase | / | 0.445 | |
| 1dgf | NDP | Catalase | 1.11.1.6 | 0.444 | |
| 1fds | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.444 | |
| 1ie8 | KH1 | Vitamin D3 receptor | / | 0.444 | |
| 1p33 | MTX | Pteridine reductase 1 | 1.5.1.33 | 0.444 | |
| 2b82 | ADN | Class B acid phosphatase | 3.1.3.2 | 0.444 | |
| 2c9z | QUE | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.444 | |
| 2cle | F6F | Tryptophan synthase alpha chain | / | 0.444 | |
| 2fpc | SCG | Strictosidine synthase | 4.3.3.2 | 0.444 | |
| 2pul | ACP | Methylthioribose kinase | 2.7.1.100 | 0.444 | |
| 2qw8 | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.444 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 2ydo | ADN | Adenosine receptor A2a | / | 0.444 | |
| 3ar7 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.444 | |
| 3b9l | AZZ | Serum albumin | / | 0.444 | |
| 3tyd | XHP | Dihydropteroate synthase | / | 0.444 | |
| 4b66 | NAP | L-ornithine N(5)-monooxygenase | / | 0.444 | |
| 4keb | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 4kp7 | 1UQ | 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic | 1.1.1.267 | 0.444 | |
| 4pah | LNR | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.444 | |
| 4rn6 | 15U | Prothrombin | 3.4.21.5 | 0.444 | |
| 1axw | MTX | Thymidylate synthase | / | 0.443 | |
| 1diu | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1efy | BZC | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.443 | |
| 1g28 | FMN | PHY3 | / | 0.443 | |
| 1kuy | COT | Serotonin N-acetyltransferase | / | 0.443 | |
| 1r8q | AFB | Cytohesin-2 | / | 0.443 | |
| 1r8q | AFB | ADP-ribosylation factor 1 | / | 0.443 | |
| 2v34 | CTN | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.443 | |
| 2vrj | NCW | Beta-glucosidase A | 3.2.1.21 | 0.443 | |
| 3ar6 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.443 | |
| 3bur | TES | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.443 | |
| 3i6q | NDP | Putative leucoanthocyanidin reductase 1 | / | 0.443 | |
| 3nxt | D2E | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 3pdt | ADP | Myosin heavy chain kinase A | 2.7.11.7 | 0.443 | |
| 3r7m | SUZ | Aldo-keto reductase family 1 member C3 | / | 0.443 | |
| 4at4 | T6E | BDNF/NT-3 growth factors receptor | 2.7.10.1 | 0.443 | |
| 4f7i | NAD | 3-isopropylmalate dehydrogenase | 1.1.1.85 | 0.443 | |
| 4gi2 | NAP | Crotonyl-CoA carboxylase/reductase | / | 0.443 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.443 | |
| 4mt9 | 2D6 | Tankyrase-1 | 2.4.2.30 | 0.443 | |
| 4mv4 | ACP | Biotin carboxylase | 6.3.4.14 | 0.443 | |
| 4pnm | NU1 | Tankyrase-2 | 2.4.2.30 | 0.443 | |
| 4ww9 | ADP | EKC/KEOPS complex subunit BUD32 | 3.6 | 0.443 | |
| 1j3k | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.442 | |
| 1ra2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1s7g | NAD | NAD-dependent protein deacylase 2 | / | 0.442 | |
| 1u0h | FOK | Adenylate cyclase type 2 | / | 0.442 | |
| 1u0h | FOK | Adenylate cyclase type 5 | / | 0.442 | |
| 1vhn | FMN | tRNA-dihydrouridine synthase | / | 0.442 | |
| 1zdw | FLV | Prenyltransferase | / | 0.442 | |
| 2b01 | TUD | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.442 | |
| 2olc | ADP | Methylthioribose kinase | 2.7.1.100 | 0.442 | |
| 2xys | SY9 | Soluble acetylcholine receptor | / | 0.442 | |
| 3arv | SAU | Chitinase A | / | 0.442 | |
| 3k45 | 51P | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 3nu0 | 3TU | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 3qm4 | PN0 | Cytochrome P450 2D6 | / | 0.442 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.442 | |
| 4j53 | 1J4 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.442 | |
| 5d1b | TSN | Histone deacetylase 8 | 3.5.1.98 | 0.442 | |
| 5esd | TDP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.442 | |
| 5h8t | RTL | Retinol-binding protein 1 | / | 0.442 | |
| 1hfr | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1odn | APV | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 1ry0 | PG2 | Aldo-keto reductase family 1 member C3 | / | 0.441 | |
| 1tdu | DUR | Thymidylate synthase | / | 0.441 | |
| 1z6t | ADP | Apoptotic protease-activating factor 1 | / | 0.441 | |
| 2oc4 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.441 | |
| 2vn1 | FK5 | Peptidylprolyl isomerase | / | 0.441 | |
| 2w6p | OA4 | Biotin carboxylase | 6.3.4.14 | 0.441 | |
| 3htj | ET | EbrA repressor | / | 0.441 | |
| 3nxy | D2H | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 4b12 | C23 | Glycylpeptide N-tetradecanoyltransferase | / | 0.441 | |
| 4dph | P65 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.441 | |
| 4h3j | 10W | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 4jq2 | SUZ | Aldo-keto reductase family 1 member C2 | / | 0.441 | |
| 5bv3 | M7G | m7GpppX diphosphatase | 3.6.1.59 | 0.441 | |
| 1ddu | DDU | Thymidylate synthase | / | 0.440 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.440 | |
| 1osv | CHC | Bile acid receptor | / | 0.440 | |
| 1qxl | FR8 | Adenosine deaminase | 3.5.4.4 | 0.440 | |
| 1syn | F89 | Thymidylate synthase | / | 0.440 | |
| 2agv | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.440 | |
| 2bla | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.440 | |
| 2oaz | I96 | Methionine aminopeptidase 2 | / | 0.440 | |
| 2w6o | OA3 | Biotin carboxylase | 6.3.4.14 | 0.440 | |
| 2zb8 | IMN | Prostaglandin reductase 2 | 1.3.1.48 | 0.440 | |
| 3dge | ADP | Sensor histidine kinase | / | 0.440 | |
| 3qpn | PFK | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.440 | |
| 3vi5 | M4M | Hematopoietic prostaglandin D synthase | / | 0.440 | |
| 3vrv | YSD | Vitamin D3 receptor | / | 0.440 | |
| 3zku | HCV | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 4hnc | 0UT | Mandelate racemase | / | 0.440 | |
| 4ite | TEY | Vitamin D3 receptor | / | 0.440 | |
| 4jbt | ASD | Cytochrome P450 monooxygenase | / | 0.440 | |
| 4lrr | CF9 | Thymidylate synthase | / | 0.440 | |
| 4uoh | ADP | Nucleoside diphosphate kinase | / | 0.440 |