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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3ttiKBIMitogen-activated protein kinase 102.7.11.24

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3ttiKBIMitogen-activated protein kinase 102.7.11.241.000
1pmn984Mitogen-activated protein kinase 102.7.11.240.665
3ttjJBIMitogen-activated protein kinase 102.7.11.240.639
2excJNKMitogen-activated protein kinase 102.7.11.240.623
2p33J07Mitogen-activated protein kinase 102.7.11.240.598
2o0uC0MMitogen-activated protein kinase 102.7.11.240.588
2o2u738Mitogen-activated protein kinase 102.7.11.240.586
2b1pAIZMitogen-activated protein kinase 102.7.11.240.576
3fi3JK2Mitogen-activated protein kinase 102.7.11.240.563
2zdt46CMitogen-activated protein kinase 102.7.11.240.553
3cgfJNFMitogen-activated protein kinase 102.7.11.240.539
4awiAQ2Mitogen-activated protein kinase 82.7.11.240.539
5awmANPStress-activated protein kinase JNK2.7.11.240.539
3k5uPFQAurora kinase A2.7.11.10.537
3f69XDRSerine/threonine-protein kinase PknB2.7.11.10.535
3kvxFMYMitogen-activated protein kinase 102.7.11.240.535
2henADPEphrin type-B receptor 22.7.10.10.527
2qoqANPEphrin type-A receptor 32.7.10.10.525
2qo7ANPEphrin type-A receptor 32.7.10.10.523
3eljGS7Mitogen-activated protein kinase 82.7.11.240.520
3gxlQIGTGF-beta receptor type-12.7.11.300.517
2xrwANPMitogen-activated protein kinase 82.7.11.240.513
5l8lADPAurora kinase A2.7.11.10.512
4o0uADNAurora kinase A2.7.11.10.511
4gk2L66Ephrin type-A receptor 32.7.10.10.510
4ux9ANPMitogen-activated protein kinase 82.7.11.240.510
2yitYITSerine/threonine-protein kinase Chk22.7.11.10.508
2h8hH8HProto-oncogene tyrosine-protein kinase Src2.7.10.20.506
1bygSTUTyrosine-protein kinase CSK/0.505
1pmv537Mitogen-activated protein kinase 102.7.11.240.504
2vx17X8Ephrin type-B receptor 42.7.10.10.504
4i22IREEpidermal growth factor receptor2.7.10.10.504
1jnkANPMitogen-activated protein kinase 102.7.11.240.503
2yirYIRSerine/threonine-protein kinase Chk22.7.11.10.503
3mpaSB2Mitogen-activated protein kinase 14/0.503
2vwz7X6Ephrin type-B receptor 42.7.10.10.502
4fv9E71Mitogen-activated protein kinase 12.7.11.240.502
5e8wSTUTGF-beta receptor type-12.7.11.300.502
3cgoJNOMitogen-activated protein kinase 102.7.11.240.501
3gubGUBDeath-associated protein kinase 12.7.11.10.501
4btjADPTau-tubulin kinase 12.7.11.10.499
4k33ACPFibroblast growth factor receptor 32.7.10.10.499
4yzcSTUSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.498
2wqeADPAurora kinase A2.7.11.10.497
3l8p0CEAngiopoietin-1 receptor2.7.10.10.497
2qo9ANPEphrin type-A receptor 32.7.10.10.495
3vs2VSBTyrosine-protein kinase HCK2.7.10.20.495
4dgnLU2Casein kinase II subunit alpha2.7.11.10.495
2rioADPSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.494
4c4f7CEDual specificity protein kinase TTK2.7.12.10.494
4g1wG1WMitogen-activated protein kinase 82.7.11.240.494
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.494
3fhyATPPyridoxal kinase2.7.1.350.493
2i4pDRHPeroxisome proliferator-activated receptor gamma/0.492
3ncgBK1Calmodulin-domain protein kinase 1, putative/0.492
2qocANPEphrin type-A receptor 32.7.10.10.491
4wkqIREEpidermal growth factor receptor2.7.10.10.491
2ghmLICMitogen-activated protein kinase 14/0.490
4fg8ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.490
4xey1N1Tyrosine-protein kinase ABL12.7.10.20.490
2h96893Mitogen-activated protein kinase 82.7.11.240.489
3flkNAITartrate dehydrogenase/decarboxylase1.1.1.930.489
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.489
1vjy460TGF-beta receptor type-12.7.11.300.488
3i60E86Mitogen-activated protein kinase 12.7.11.240.488
4c4h7RODual specificity protein kinase TTK2.7.12.10.488
4en4ATPPyridoxal kinase2.7.1.350.488
4fhk0U0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.488
4g2fC07Ephrin type-A receptor 32.7.10.10.488
4yuqKS1Calmodulin-like domain protein kinase/0.488
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.487
2xk9XK9Serine/threonine-protein kinase Chk22.7.11.10.487
4utdACPAurora kinase A2.7.11.10.487
3vquO22Dual specificity protein kinase TTK2.7.12.10.486
4gmy0X5Tyrosine-protein kinase JAK2/0.486
4nka2K7Fibroblast growth factor receptor 1/0.486
4riyADPEpidermal growth factor receptor2.7.10.10.486
5e8xSTUTGF-beta receptor type-12.7.11.300.486
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.485
2xvdAS6Ephrin type-B receptor 42.7.10.10.485
2ycqUPXSerine/threonine-protein kinase Chk22.7.11.10.485
3hmm855TGF-beta receptor type-12.7.11.300.485
4lopSB4Mitogen-activated protein kinase 14/0.485
1eh4IC1Casein kinase I homolog 12.7.11.10.484
1yw2PGJMitogen-activated protein kinase 14/0.484
2itzIREEpidermal growth factor receptor2.7.10.10.484
3gc8B45Mitogen-activated protein kinase 112.7.11.240.484
4mcv29KProto-oncogene tyrosine-protein kinase Src2.7.10.20.484
3f5p741Insulin-like growth factor 1 receptor2.7.10.10.483
3w1f1O5Dual specificity protein kinase TTK2.7.12.10.483
4hyu1BKMitogen-activated protein kinase 82.7.11.240.483
4bibIEOMitogen-activated protein kinase kinase kinase 52.7.11.250.482
4jbqVX6Aurora kinase A2.7.11.10.482
4o0rX4ZSerine/threonine-protein kinase PAK 12.7.11.10.482
1qcfPP1Tyrosine-protein kinase HCK2.7.10.20.481
2w7xD1ASerine/threonine-protein kinase Chk22.7.11.10.481
4bgg844Activin receptor type-12.7.11.300.481
1ipeNDPTropinone reductase 21.1.1.2360.480
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.480
3gc9B45Mitogen-activated protein kinase 112.7.11.240.480
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.480
4gk3L87Ephrin type-A receptor 32.7.10.10.480
4jia1K3Tyrosine-protein kinase JAK2/0.480
2y6o1N1Ephrin type-A receptor 42.7.10.10.479
3vrzVRZTyrosine-protein kinase HCK2.7.10.20.479
4id71G0Activated CDC42 kinase 1/0.479
4jboWPHAurora kinase A2.7.11.10.479
5dmzADPMitotic checkpoint serine/threonine-protein kinase BUB12.7.11.10.479
2j0m4STFocal adhesion kinase 12.7.10.20.478
3efwAK8Aurora kinase A2.7.11.10.478
3lj3WYEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.478
4c4g7RODual specificity protein kinase TTK2.7.12.10.478
4hnf16WCasein kinase I isoform delta2.7.11.10.478
4kbk1QGCasein kinase I isoform delta2.7.11.10.478
3w18N13Aurora kinase A2.7.11.10.477
4jbpYPHAurora kinase A2.7.11.10.477
5cvhADPCasein kinase II subunit alpha2.7.11.10.477
2wotZZGTGF-beta receptor type-12.7.11.300.476
2xp2VGHALK tyrosine kinase receptor2.7.10.10.476
4b0gVEKAurora kinase A2.7.11.10.476
4btjATPTau-tubulin kinase 12.7.11.10.476
4elf35IDihydrofolate reductase/0.476
4lrjANPUncharacterized protein/0.476
5ajqDB8Serine/threonine-protein kinase 102.7.11.10.476
3s4qNK0Mitogen-activated protein kinase 14/0.475
4lfiGNPCasein kinase II subunit alpha2.7.11.10.475
4loqSB4Mitogen-activated protein kinase 14/0.475
2c6eHPMAurora kinase A2.7.11.10.474
2pwlACPFibroblast growth factor receptor 2/0.474
2yiqYIQSerine/threonine-protein kinase Chk22.7.11.10.474
2yxuATPPyridoxal kinase2.7.1.350.474
1q41IXMGlycogen synthase kinase-3 beta2.7.11.260.473
2i4jDRJPeroxisome proliferator-activated receptor gamma/0.473
2vwy7X5Ephrin type-B receptor 42.7.10.10.473
3kf7L9GMitogen-activated protein kinase 14/0.473
3nwq2NCGag-Pol polyprotein3.4.23.160.473
4bi0Z0WDual specificity protein kinase TTK2.7.12.10.473
4j97ACPFibroblast growth factor receptor 2/0.473
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.472
1ouk084Mitogen-activated protein kinase 14/0.472
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.472
2i4zDRHPeroxisome proliferator-activated receptor gamma/0.472
2w0jZATSerine/threonine-protein kinase Chk22.7.11.10.472
3flsFLSMitogen-activated protein kinase 14/0.472
3ggfGVDSerine/threonine-protein kinase 26/0.472
4b99R4LMitogen-activated protein kinase 72.7.11.240.472
4zseANPEpidermal growth factor receptor2.7.10.10.472
5c03AGSNon-receptor tyrosine-protein kinase TYK22.7.10.20.472
1u54ACPActivated CDC42 kinase 1/0.471
2xm9LWHSerine/threonine-protein kinase Chk22.7.11.10.471
3oom507Activin receptor type-12.7.11.300.471
3umoATPATP-dependent 6-phosphofructokinase isozyme 22.7.1.110.471
4bi1ZO6Dual specificity protein kinase TTK2.7.12.10.471
4ele31IDihydrofolate reductase/0.471
1e3eNAIAlcohol dehydrogenase 41.1.1.10.470
2xs0ANPMitogen-activated protein kinase 82.7.11.240.470
3vthAPCCarbamoyltransferase/0.470
4acc7YGGlycogen synthase kinase-3 beta2.7.11.260.470
4ansVGHALK tyrosine kinase receptor2.7.10.10.470
4d0l093Phosphatidylinositol 4-kinase beta2.7.1.670.470
4e730NRMitogen-activated protein kinase 82.7.11.240.470
4l9kEHFSerum albumin/0.470
2vx07X7Ephrin type-B receptor 42.7.10.10.469
4hvi19STyrosine-protein kinase JAK32.7.10.20.469
4kba1QMCasein kinase I isoform delta2.7.11.10.469
1q97ATPSerine/threonine-protein kinase SKY12.7.11.10.468
2pvnP63Casein kinase II subunit alpha2.7.11.10.468
2yn8STUEphrin type-B receptor 42.7.10.10.468
3uyt0CKCasein kinase I isoform delta2.7.11.10.468
4qpmADPMitotic checkpoint serine/threonine-protein kinase BUB12.7.11.10.468
5bvw1N1Epithelial discoidin domain-containing receptor 12.7.10.10.468
1jpaANPEphrin type-B receptor 22.7.10.10.467
2b9iADPMitogen-activated protein kinase FUS32.7.11.240.467
3hllI45Mitogen-activated protein kinase 14/0.467
3mdvCL6Cholesterol 24-hydroxylase/0.467
3uvqFS8Mitogen-activated protein kinase 14/0.467
3vs1VSATyrosine-protein kinase HCK2.7.10.20.467
3zsgT75Mitogen-activated protein kinase 14/0.467
4nfn2KCTau-tubulin kinase 12.7.11.10.467
1xkkFMMEpidermal growth factor receptor2.7.10.10.466
2ijmATPFocal adhesion kinase 12.7.10.20.466
2x9fX9FEphrin type-B receptor 42.7.10.10.466
3mvl38PMitogen-activated protein kinase 14/0.466
4fuyEK2Mitogen-activated protein kinase 12.7.11.240.466
4mxxDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.466
5dn3ATPAurora kinase A2.7.11.10.466
1om1IQACasein kinase II subunit alpha2.7.11.10.465
1xr1ANPSerine/threonine-protein kinase pim-12.7.11.10.465
2xa4AZ5Tyrosine-protein kinase JAK2/0.465
3fl8RARDihydrofolate reductase/0.465
3l1sZ92Glycogen synthase kinase-3 beta2.7.11.260.465
3t2zFADSulfide-quinone reductase/0.465
4anmWULCasein kinase II subunit alpha2.7.11.10.465
4elg52JDihydrofolate reductase/0.465
4feq0T8Tyrosine-protein kinase receptor TYRO32.7.10.10.465
4hwkNAPSepiapterin reductase1.1.1.1530.465
5amnDTQProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.465
5auwQUEDeath-associated protein kinase 12.7.11.10.465
1rw8580TGF-beta receptor type-12.7.11.300.464
1zeoC01Peroxisome proliferator-activated receptor gamma/0.464
1zyjBI5Mitogen-activated protein kinase 14/0.464
2itvANPEpidermal growth factor receptor2.7.10.10.464
2py3ACPFibroblast growth factor receptor 2/0.464
2vwx7X4Ephrin type-B receptor 42.7.10.10.464
2w9sTOPDihydrofolate reductase type 1 from Tn40031.5.1.30.464
3hrfATP3-phosphoinositide-dependent protein kinase 12.7.11.10.464
4h8nNDPNADPH-dependent conjugated polyketone reductase C2/0.464
4k181OBSerine/threonine-protein kinase pim-12.7.11.10.464
4pl4ADPSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.464
1u4dDBQActivated CDC42 kinase 1/0.463
2hog710Serine/threonine-protein kinase Chk12.7.11.10.463
2vwu7X1Ephrin type-B receptor 42.7.10.10.463
2x4f16XMyosin light chain kinase family member 42.7.11.10.463
3qwfNAP17beta-hydroxysteroid dehydrogenase/0.463
3w2sW2REpidermal growth factor receptor2.7.10.10.463
4jr7GNPCasein kinase II subunit alpha2.7.11.10.463
4k110J9Proto-oncogene tyrosine-protein kinase Src2.7.10.20.463
5dt3ATPAurora kinase A2.7.11.10.463
1gufNDPEnoyl-[acyl-carrier-protein] reductase 1, mitochondrial1.3.1.100.462
3tkh07SSerine/threonine-protein kinase Chk12.7.11.10.462
3umpATPATP-dependent 6-phosphofructokinase isozyme 22.7.1.110.462
4bc6XZNSerine/threonine-protein kinase 102.7.11.10.462
4cd0AWJALK tyrosine kinase receptor2.7.10.10.462
4gk4L90Ephrin type-A receptor 32.7.10.10.462
4kikKSAInhibitor of nuclear factor kappa-B kinase subunit beta2.7.11.100.462
1di8DTQCyclin-dependent kinase 22.7.11.220.461
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.461
2pvhP19Casein kinase II subunit alpha2.7.11.10.461
2w1fL0FAurora kinase A2.7.11.10.461
2x2mX2MProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.461
2ym6YM6Serine/threonine-protein kinase Chk12.7.11.10.461
3hx4ANPCalmodulin-domain protein kinase 1/0.461
3oriAGSSerine/threonine protein kinase/0.461
3t2kFADSulfide-quinone reductase/0.461
4anqVGHALK tyrosine kinase receptor2.7.10.10.461
4dymIYZActivin receptor type-12.7.11.300.461
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.461
4nk92K5Fibroblast growth factor receptor 1/0.461
5e92ANPTGF-beta receptor type-22.7.11.300.461
1jioDEB6-deoxyerythronolide B hydroxylase/0.460
2j0lANPFocal adhesion kinase 12.7.10.20.460
3igoANPCalmodulin-domain protein kinase 1, putative/0.460
3ormAGSSerine/threonine protein kinase/0.460
3t2yFADSulfide-quinone reductase/0.460
3vs0VS0Tyrosine-protein kinase HCK2.7.10.20.460
3zm422TDual specificity mitogen-activated protein kinase kinase 12.7.12.20.460
4bidIE8Mitogen-activated protein kinase kinase kinase 52.7.11.250.460
4enhFVXCholesterol 24-hydroxylase/0.460
4ft0HK9Serine/threonine-protein kinase Chk12.7.11.10.460
4jqeANPCasein kinase II subunit alpha2.7.11.10.460
1aq1STUCyclin-dependent kinase 22.7.11.220.459
1dawANPCasein kinase II subunit alpha2.7.11.10.459
1tdrMTXDihydrofolate reductase1.5.1.30.459
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.459
2ycrHCWSerine/threonine-protein kinase Chk22.7.11.10.459
3hl7I47Mitogen-activated protein kinase 14/0.459
3keuATPPyridoxal kinase2.7.1.350.459
3tea4CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.459
3uzp0CKCasein kinase I isoform delta2.7.11.10.459
4bfmANPMaternal embryonic leucine zipper kinase2.7.11.10.459
4fsnA58Serine/threonine-protein kinase Chk12.7.11.10.459
4hge15VTyrosine-protein kinase JAK2/0.459
1dayGNPCasein kinase II subunit alpha2.7.11.10.458
1wlvCOAPhenylacetic acid degradation protein PaaI/0.458
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.458
2hk51BMTyrosine-protein kinase HCK2.7.10.20.458
3cblSTUTyrosine-protein kinase Fes/Fps2.7.10.20.458
4btkDTQTau-tubulin kinase 12.7.11.10.458
4c58824Cyclin-G-associated kinase2.7.11.10.458
4eh70OOMitogen-activated protein kinase 14/0.458
4fswHK6Serine/threonine-protein kinase Chk12.7.11.10.458
4wsqKSAAP2-associated protein kinase 12.7.11.10.458
1i44ACPInsulin receptor2.7.10.10.457
1jld0PPGag-Pol polyprotein/0.457
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.457
2bhhRYUCyclin-dependent kinase 22.7.11.220.457
2cgx3D3Serine/threonine-protein kinase Chk12.7.11.10.457
2q61SF1Peroxisome proliferator-activated receptor gamma/0.457
3mtfA3FActivin receptor type-12.7.11.300.457
3sz0FADSulfide-quinone reductase/0.457
3ztxZTXAurora kinase B-A2.7.11.10.457
4a06ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.457
4gj30XPNon-receptor tyrosine-protein kinase TYK22.7.10.20.457
4qmlANPSerine/threonine-protein kinase 242.7.11.10.457
5ap57RODual specificity protein kinase TTK2.7.12.10.457
1bsvNDPGDP-L-fucose synthase/0.456
1pkgADPMast/stem cell growth factor receptor Kit2.7.10.10.456
2x2lX2LProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.456
3apfBMWPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.456
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.456
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.456
4bb432WEphrin type-B receptor 42.7.10.10.456
4ix5ANPUncharacterized protein/0.456
4qmzB49Serine/threonine-protein kinase 242.7.11.10.456
5ap7SVEDual specificity protein kinase TTK2.7.12.10.456
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.455
2xchCKG3-phosphoinositide-dependent protein kinase 12.7.11.10.455
3v5l0G1Tyrosine-protein kinase ITK/TSK2.7.10.20.455
4acg6LQGlycogen synthase kinase-3 beta2.7.11.260.455
4f640S8Fibroblast growth factor receptor 1/0.455
4hys1BJMitogen-activated protein kinase 82.7.11.240.455
4ic7ANPMitogen-activated protein kinase 72.7.11.240.455
1kboFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.454
1ol6ATPAurora kinase A2.7.11.10.454
1stcSTUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.454
2bfyH1NAurora kinase B-A2.7.11.10.454
2ivuZD6Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.454
3a4oSTUTyrosine-protein kinase Lyn2.7.10.20.454
3at4CCKCasein kinase II subunit alpha2.7.11.10.454
3be9P04Casein kinase II subunit alpha2.7.11.10.454
3cy2MB9Serine/threonine-protein kinase pim-12.7.11.10.454
3gfbNADL-threonine 3-dehydrogenase/0.454
3gu7ADPDeath-associated protein kinase 12.7.11.10.454
3r324CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.454
3zewSTUEphrin type-B receptor 42.7.10.10.454
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.454
4dn5AGSMitogen-activated protein kinase kinase kinase 142.7.11.250.454
4eor4SPCyclin-dependent kinase 22.7.11.220.454
4hvh19RTyrosine-protein kinase JAK32.7.10.20.454
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.454
4l7sG7KTyrosine-protein kinase ITK/TSK2.7.10.20.454
5drdATPAurora kinase A2.7.11.10.454
1qpdSTUTyrosine-protein kinase Lck2.7.10.20.453
2izsBRQCasein kinase I isoform gamma-32.7.11.10.453
2j0k4STFocal adhesion kinase 12.7.10.20.453
3ckxSTUSerine/threonine-protein kinase 242.7.11.10.453
3flwFLWMitogen-activated protein kinase 14/0.453
3g49NAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.453
3nww3NWMitogen-activated protein kinase 14/0.453
3syiFADSulfide-quinone reductase/0.453
3w16P9JAurora kinase A2.7.11.10.453
4bcmT7ZCyclin-dependent kinase 22.7.11.220.453
4y93746Tyrosine-protein kinase/0.453
1oecAA2Fibroblast growth factor receptor 2/0.452
1xl5190Gag-Pol polyprotein3.4.23.160.452
2bmcMPYAurora kinase A2.7.11.10.452
2gcdSTUSerine/threonine-protein kinase TAO22.7.11.10.452
2itnANPEpidermal growth factor receptor2.7.10.10.452
2ittAEEEpidermal growth factor receptor2.7.10.10.452
2j4z626Aurora kinase A2.7.11.10.452
2pzpACPFibroblast growth factor receptor 2/0.452
2yfxVGHALK tyrosine kinase receptor2.7.10.10.452
3a99ANPSerine/threonine-protein kinase pim-12.7.11.10.452
3c4wATPRhodopsin kinase/0.452
3c7qXINVascular endothelial growth factor receptor 22.7.10.10.452
3iahNAPPutative oxoacyl-(Acyl carrier protein) reductase/0.452
3jxwLXGSerine/threonine-protein kinase pim-12.7.11.10.452
3r34COA4-hydroxybenzoyl-CoA thioesterase3.1.2.230.452
4aw1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.452
4e4m0NHTyrosine-protein kinase JAK2/0.452
4fg9ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.452
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.452
4ftiH7KSerine/threonine-protein kinase Chk12.7.11.10.452
4hle17VPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.452
4jq8KJ8Epidermal growth factor receptor2.7.10.10.452
4k8aK8AFocal adhesion kinase 12.7.10.20.452
5dt4ATPAurora kinase A2.7.11.10.452
9hvp0E9Gag-Pol polyprotein/0.452
1w87NAPFerredoxin--NADP reductase1.18.1.20.451
1y0s331Peroxisome proliferator-activated receptor delta/0.451
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.451
2x6dX6DAurora kinase A2.7.11.10.451
3bu5ATPInsulin receptor2.7.10.10.451
3h0aD30Peroxisome proliferator-activated receptor gamma/0.451
3vs7KS1Tyrosine-protein kinase HCK2.7.10.20.451
3vw6IM6Mitogen-activated protein kinase kinase kinase 52.7.11.250.451
4anwO92Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.451
4dgmAGICasein kinase II subunit alpha2.7.11.10.451
4yr9NADL-threonine 3-dehydrogenase, mitochondrial1.1.1.1030.451
5kjeNAJAlcohol dehydrogenase E chain1.1.1.10.451
1ad5ANPTyrosine-protein kinase HCK2.7.10.20.450
1o6yACPSerine/threonine-protein kinase PknB2.7.11.10.450
1pmeSB2Mitogen-activated protein kinase 12.7.11.240.450
1siqFADGlutaryl-CoA dehydrogenase, mitochondrial1.3.8.60.450
2bdjHETProto-oncogene tyrosine-protein kinase Src2.7.10.20.450
2q5g1FAPeroxisome proliferator-activated receptor delta/0.450
2x1nX1NCyclin-dependent kinase 22.7.11.220.450
3cxw7CPSerine/threonine-protein kinase pim-12.7.11.10.450
3rkb12ZCyclin-dependent kinase 22.7.11.220.450
3sheI85MAP kinase-activated protein kinase 32.7.11.10.450
3t14FADSulfide-quinone reductase/0.450
3vs6VSHTyrosine-protein kinase HCK2.7.10.20.450
4ezk0SDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.450
4fod0UVALK tyrosine kinase receptor2.7.10.10.450
4jbiNDPAlcohol dehydrogenase (Zinc)/0.450
4qnyANPMitogen activated protein kinase, putative/0.450
1d4aFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.449
1okySTU3-phosphoinositide-dependent protein kinase 12.7.11.10.449
2etm7PYFocal adhesion kinase 12.7.10.20.449
2ycfYCFSerine/threonine-protein kinase Chk22.7.11.10.449
3r374CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.449
3stxBKAMethylketone synthase I/0.449
3w33W19Epidermal growth factor receptor2.7.10.10.449
4c02TAKActivin receptor type-12.7.11.300.449
4c3rACPAurora kinase A2.7.11.10.449
4grb0XGCasein kinase II subunit alpha2.7.11.10.449
4j95ACPFibroblast growth factor receptor 2/0.449
4nb6444Nuclear receptor ROR-gamma/0.449
5dnrATPAurora kinase A2.7.11.10.449
1mgoNADAlcohol dehydrogenase E chain1.1.1.10.448
1uv5BRWGlycogen synthase kinase-3 beta2.7.11.260.448
2cmjNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.448
2qa2FADPolyketide oxygenase CabE/0.448
2r5tANPSerine/threonine-protein kinase Sgk12.7.11.10.448
3cukFADD-amino-acid oxidase1.4.3.30.448
3fmmXI2Mitogen-activated protein kinase 14/0.448
3poz03PEpidermal growth factor receptor2.7.10.10.448
3r3c4CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.448
3t8oATPRhodopsin kinase/0.448
3tqhNDPQuinone oxidoreductase/0.448
3vs4VSFTyrosine-protein kinase HCK2.7.10.20.448
4fg7ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.448
4fuxE75Mitogen-activated protein kinase 12.7.11.240.448
4ii5ADPCyclin-dependent kinase 22.7.11.220.448
4nj32KDCyclin-dependent kinase 22.7.11.220.448
4xlvACPInsulin receptor2.7.10.10.448
1f3pNADFerredoxin reductase/0.447
1gg5FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.447
1ny3ADPMAP kinase-activated protein kinase 22.7.11.10.447
1ol5ADPAurora kinase A2.7.11.10.447
2c3kABOSerine/threonine-protein kinase Chk12.7.11.10.447
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.447
3uimANPBRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 12.7.10.10.447
3zep1NXTyrosine-protein kinase JAK32.7.10.20.447
4anuEM7Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
4aotGW8Serine/threonine-protein kinase 102.7.11.10.447
4c4iX20Dual specificity protein kinase TTK2.7.12.10.447
4enxZ20Serine/threonine-protein kinase pim-12.7.11.10.447
4gvjADPNon-receptor tyrosine-protein kinase TYK22.7.10.20.447
4jlcSU6Serine/threonine-protein kinase TBK12.7.11.10.447
4ma628EAra h 8 allergen/0.447
1gheACOAcetyltransferase2.3.10.446
1t0lNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.446
1tduCB3Thymidylate synthase/0.446
1w4zNAPPutative ketoacyl reductase1.3.10.446
1yvj4STTyrosine-protein kinase JAK32.7.10.20.446
2izrBRKCasein kinase I isoform gamma-32.7.11.10.446
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.446
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.446
2zdu446Mitogen-activated protein kinase 102.7.11.240.446
3a7hATPSerine/threonine-protein kinase 242.7.11.10.446
3c4xATPRhodopsin kinase/0.446
3ma301ISerine/threonine-protein kinase pim-12.7.11.10.446
3ml8ML8Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
3ue4DB8Tyrosine-protein kinase ABL12.7.10.20.446
4l521ULMitogen-activated protein kinase kinase kinase 72.7.11.250.446
4looSB4Mitogen-activated protein kinase 14/0.446
4s34ANPMitogen-activated protein kinase 12.7.11.240.446
1gqtACPRibokinase/0.445
1heuNADAlcohol dehydrogenase E chain1.1.1.10.445
1qxsNADGlyceraldehyde-3-phosphate dehydrogenase, glycosomal1.2.1.120.445
1tvoFRZMitogen-activated protein kinase 12.7.11.240.445
2cciATPCyclin-dependent kinase 22.7.11.220.445
2dr3ADPUPF0273 protein PH0284/0.445
2w17I19Cyclin-dependent kinase 22.7.11.220.445
2w1eL0EAurora kinase A2.7.11.10.445
2xpwOTCTetracycline repressor protein class D/0.445
3a60STURibosomal protein S6 kinase beta-12.7.11.10.445
3cylVITBasic phospholipase A2 homolog piratoxin-2/0.445
3fc152PMitogen-activated protein kinase 14/0.445
3gb2G3BGlycogen synthase kinase-3 beta2.7.11.260.445
3lpbNVBTyrosine-protein kinase JAK2/0.445
3vs3VSETyrosine-protein kinase HCK2.7.10.20.445
3zw3ZW3Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
3zxtACPDeath-associated protein kinase 12.7.11.10.445
4c4jX21Dual specificity protein kinase TTK2.7.12.10.445
4h50NAPBiphenyl dioxygenase ferredoxin reductase subunit/0.445
4kb81QNCasein kinase I isoform delta2.7.11.10.445
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.445
5adhAPRAlcohol dehydrogenase E chain1.1.1.10.445
1j1cADPGlycogen synthase kinase-3 beta2.7.11.260.444
1j39UPGDNA beta-glucosyltransferase/0.444
1yb5NAPQuinone oxidoreductase1.6.5.50.444
2c3qGTXGlutathione S-transferase theta-12.5.1.180.444
2np8CC3Aurora kinase A2.7.11.10.444
2ycsNXPSerine/threonine-protein kinase Chk22.7.11.10.444
2znnS44Peroxisome proliferator-activated receptor alpha/0.444
3bi6396Wee1-like protein kinase2.7.10.20.444
3cjgKIMVascular endothelial growth factor receptor 22.7.10.10.444
3gi6D78Gag-Pol polyprotein/0.444
3gu83GUDeath-associated protein kinase 12.7.11.10.444
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.444
3orpAGSSerine/threonine protein kinase/0.444
3qyw6PBMitogen-activated protein kinase 12.7.11.240.444
3r3d4CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.444
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.444
3upkUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.444
3wfjNAD2-dehydropantoate 2-reductase/0.444
4a4vYFDPeroxisome proliferator-activated receptor gamma/0.444
4e6q0NVTyrosine-protein kinase JAK2/0.444
4f650S9Fibroblast growth factor receptor 1/0.444
4fl3ANPTyrosine-protein kinase SYK2.7.10.20.444
4gfo0X2Non-receptor tyrosine-protein kinase TYK22.7.10.20.444
4nks2M2Fibroblast growth factor receptor 1/0.444
5aacVGHALK tyrosine kinase receptor2.7.10.10.444
5eg3ACPFibroblast growth factor receptor 2/0.444
1csnATPCasein kinase I homolog 12.7.11.10.443
1e9hINRCyclin-dependent kinase 22.7.11.220.443
1ie4T44Transthyretin/0.443
1pkdUCNCyclin-dependent kinase 22.7.11.220.443
2bdf24AProto-oncogene tyrosine-protein kinase Src2.7.10.20.443
2dcnADP2-keto-3-deoxy-gluconate kinase/0.443
2iw84SPCyclin-dependent kinase 22.7.11.220.443
2xikJ60Serine/threonine-protein kinase 252.7.11.10.443
3fmjFMJMitogen-activated protein kinase 14/0.443
3my5RFZCyclin-dependent kinase 22.7.11.220.443
3ogqAB1Pol polyprotein/0.443
3s2pPMUCyclin-dependent kinase 22.7.11.220.443
4ckiADNProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.443
4eevL1XHepatocyte growth factor receptor2.7.10.10.443
4jnkZHKL-lactate dehydrogenase A chain1.1.1.270.443
4k1b1OCSerine/threonine-protein kinase pim-12.7.11.10.443
4l7f1V5Mitogen-activated protein kinase 82.7.11.240.443
4n702HXSerine/threonine-protein kinase pim-12.7.11.10.443
4xguADPPutative pachytene checkpoint protein 2/0.443
5kjcNAJAlcohol dehydrogenase E chain1.1.1.10.443
1h1wATP3-phosphoinositide-dependent protein kinase 12.7.11.10.442
1h69FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.442
1ir3ANPInsulin receptor2.7.10.10.442
1oitHDTCyclin-dependent kinase 22.7.11.220.442
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.442
2p4yC03Peroxisome proliferator-activated receptor gamma/0.442
2xngA0HAurora kinase A2.7.11.10.442
3b8r887Vascular endothelial growth factor receptor 22.7.10.10.442
3fmkFMKMitogen-activated protein kinase 14/0.442
3kpkFADSulfide-quinone reductase/0.442
3mqe416Prostaglandin G/H synthase 21.14.99.10.442
3slkNDPPolyketide synthase extender module 2/0.442
3vryB43Tyrosine-protein kinase HCK2.7.10.20.442
3zc3NAPFerredoxin--NADP reductase1.18.1.20.442
4aqc88ATyrosine-protein kinase JAK2/0.442
4aw0ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.442
4dshFDAUncharacterized protein/0.442
4ft5H2KSerine/threonine-protein kinase Chk12.7.11.10.442
4hvb19PPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
4j7uNAPSepiapterin reductase1.1.1.1530.442
4q71FADBifunctional protein PutA/0.442
4wx1FDAUDP-galactopyranose mutase/0.442
1g5sI17Cyclin-dependent kinase 22.7.11.220.441
1iyzNDPProbable quinone oxidoreductase/0.441
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.441
1xjdSTUProtein kinase C theta type2.7.11.130.441
2j0j4STFocal adhesion kinase 12.7.10.20.441
2o7oDXTTetracycline repressor protein class D/0.441
2w1gL0GAurora kinase A2.7.11.10.441
3hu1AGSTransitional endoplasmic reticulum ATPase3.6.4.60.441
3oy4017Gag-Pol polyprotein3.4.23.160.441
3zh8C58Protein kinase C iota type2.7.11.130.441
4dit0KDGlycogen synthase kinase-3 beta2.7.11.260.441
4fad0TBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
4gj20XHNon-receptor tyrosine-protein kinase TYK22.7.10.20.441
4hgt15GCasein kinase I isoform delta2.7.11.10.441
4ly91YYGlucokinase regulatory protein/0.441
4nfsNAJAlcohol dehydrogenase E chain1.1.1.10.441
4q73FADBifunctional protein PutA/0.441
4qmnDB8Serine/threonine-protein kinase 242.7.11.10.441
4qmpDKISerine/threonine-protein kinase 242.7.11.10.441
4qmxH8HSerine/threonine-protein kinase 242.7.11.10.441
4r21STRCytochrome P450 family 17 polypeptide 2/0.441
1bdrIM1Gag-Pol polyprotein3.4.23.160.440
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.440
2c0tL3GTyrosine-protein kinase HCK2.7.10.20.440
2c475IDCasein kinase I isoform gamma-2/0.440
2ji8FYNOxalyl-CoA decarboxylase4.1.1.80.440
2pe24643-phosphoinositide-dependent protein kinase 12.7.11.10.440
2w03ADNAcsD/0.440
2wmxZY6Serine/threonine-protein kinase Chk12.7.11.10.440
2wtcVGMSerine/threonine-protein kinase Chk22.7.11.10.440
2ywwATPAspartate carbamoyltransferase regulatory chain/0.440
3a1nNADNDP-sugar epimerase/0.440
3inmNDPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.440
3jw3TOPDihydrofolate reductase/0.440
3nxe2NCProtease/0.440
3qcq3Q03-phosphoinositide-dependent protein kinase 12.7.11.10.440
3u4cNDPNADPH-dependent reductase BacG/0.440
3zc6VFCTyrosine-protein kinase JAK32.7.10.20.440
4b7dQLECytochrome P450 monooxygenase PikC/0.440
4erwSTUCyclin-dependent kinase 22.7.11.220.440
4hw319GInduced myeloid leukemia cell differentiation protein Mcl-1/0.440
4r8qADPMitotic checkpoint serine/threonine-protein kinase BUB12.7.11.10.440
5aaaVGHALK tyrosine kinase receptor2.7.10.10.440
5dpvSKEAurora kinase A2.7.11.10.440
5hhfFDAUDP-galactopyranose mutase/0.440