sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3srq | Q19 | Dihydrofolate reductase | 1.5.1.3 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3srq | Q19 | Dihydrofolate reductase | 1.5.1.3 | 1.000 | |
| 4fgg | 0U5 | Dihydrofolate reductase | 1.5.1.3 | 0.642 | |
| 4xe6 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.637 | |
| 3fre | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.626 | |
| 3srw | Q27 | Dihydrofolate reductase | 1.5.1.3 | 0.612 | |
| 3frd | DHF | Dihydrofolate reductase | 1.5.1.3 | 0.604 | |
| 2w3v | TOP | Dihydrofolate reductase | / | 0.602 | |
| 3jwm | 5WB | Dihydrofolate reductase | / | 0.583 | |
| 2w9s | TOP | Dihydrofolate reductase type 1 from Tn4003 | 1.5.1.3 | 0.580 | |
| 3fy9 | XCF | Dihydrofolate reductase | 1.5.1.3 | 0.578 | |
| 3jw5 | TOP | Dihydrofolate reductase | / | 0.578 | |
| 3kjs | DQ1 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.578 | |
| 3fyw | XCF | Dihydrofolate reductase | 1.5.1.3 | 0.576 | |
| 3jwc | EKB | Dihydrofolate reductase | / | 0.574 | |
| 3qlz | QLZ | Uncharacterized protein | / | 0.572 | |
| 2fzi | DH3 | Dihydrofolate reductase | 1.5.1.3 | 0.570 | |
| 3fl8 | RAR | Dihydrofolate reductase | / | 0.570 | |
| 3sh2 | 5DR | Dihydrofolate reductase | 1.5.1.3 | 0.565 | |
| 3m08 | RAR | Dihydrofolate reductase | 1.5.1.3 | 0.562 | |
| 3sa2 | 7DR | Dihydrofolate reductase | / | 0.562 | |
| 1dds | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.556 | |
| 3frf | XCF | Dihydrofolate reductase | 1.5.1.3 | 0.555 | |
| 2zza | FOL | Dihydrofolate reductase | / | 0.554 | |
| 1vj3 | TAB | Dihydrofolate reductase | 1.5.1.3 | 0.552 | |
| 2w9g | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.552 | |
| 3eek | 53S | Uncharacterized protein | / | 0.552 | |
| 3dfr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.551 | |
| 3inv | C50 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.551 | |
| 4fgh | 0U6 | Dihydrofolate reductase | 1.5.1.3 | 0.549 | |
| 1cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.548 | |
| 3cse | N22 | Uncharacterized protein | / | 0.548 | |
| 3sa1 | 6DR | Dihydrofolate reductase | / | 0.548 | |
| 4ele | 31I | Dihydrofolate reductase | / | 0.547 | |
| 1diu | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.546 | |
| 2fzh | DH1 | Dihydrofolate reductase | 1.5.1.3 | 0.546 | |
| 3eej | 53R | Uncharacterized protein | / | 0.546 | |
| 1rx3 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.544 | |
| 1dg5 | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.543 | |
| 4elg | 52J | Dihydrofolate reductase | / | 0.543 | |
| 3ia4 | MTX | Dihydrofolate reductase | / | 0.540 | |
| 1jol | FFO | Dihydrofolate reductase | 1.5.1.3 | 0.539 | |
| 3sai | 9DR | Dihydrofolate reductase | / | 0.533 | |
| 3srr | Q20 | Dihydrofolate reductase | 1.5.1.3 | 0.533 | |
| 3sru | Q26 | Dihydrofolate reductase | 1.5.1.3 | 0.532 | |
| 3fra | I2H | Dihydrofolate reductase | 1.5.1.3 | 0.531 | |
| 3fy8 | XCF | Dihydrofolate reductase | 1.5.1.3 | 0.530 | |
| 4elb | 34R | Dihydrofolate reductase | / | 0.530 | |
| 5ccc | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.529 | |
| 1klk | PMD | Dihydrofolate reductase | 1.5.1.3 | 0.528 | |
| 4h96 | 14Q | Dihydrofolate reductase | 1.5.1.3 | 0.528 | |
| 4p66 | MTX | Dihydrofolate reductase | / | 0.528 | |
| 3td8 | D2R | Dihydrofolate reductase | 1.5.1.3 | 0.527 | |
| 4h98 | 14Q | Uncharacterized protein | / | 0.526 | |
| 3eel | 53T | Uncharacterized protein | / | 0.524 | |
| 3qly | 55V | Uncharacterized protein | / | 0.524 | |
| 1re7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.521 | |
| 3eem | 53V | Uncharacterized protein | / | 0.521 | |
| 3jw3 | TOP | Dihydrofolate reductase | / | 0.520 | |
| 4m2x | TMQ | Dihydrofolate reductase | 1.5.1.3 | 0.520 | |
| 2cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.519 | |
| 3srs | M23 | Dihydrofolate reductase | 1.5.1.3 | 0.519 | |
| 1df7 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.518 | |
| 2w3w | VG9 | Dihydrofolate reductase | / | 0.518 | |
| 3qlx | QLR | Uncharacterized protein | / | 0.518 | |
| 4dfr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.516 | |
| 3fyv | XCF | Dihydrofolate reductase | 1.5.1.3 | 0.515 | |
| 2drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.513 | |
| 3och | 2MX | Dihydrofolate reductase | 1.5.1.3 | 0.513 | |
| 4ixe | IXE | Dihydrofolate reductase | 1.5.1.3 | 0.513 | |
| 4nx7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.513 | |
| 3dga | RJ1 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.510 | |
| 3tq9 | MTX | Dihydrofolate reductase | / | 0.508 | |
| 3jsu | KA5 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.507 | |
| 4cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.507 | |
| 4h95 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.507 | |
| 3qfx | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.506 | |
| 3qls | 55V | Dihydrofolate reductase | 1.5.1.3 | 0.505 | |
| 4x5g | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.505 | |
| 4dph | P65 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.503 | |
| 3sgy | 06W | Dihydrofolate reductase | 1.5.1.3 | 0.502 | |
| 4dpd | DHF | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.502 | |
| 4nx6 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.502 | |
| 1j3i | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.501 | |
| 1dg7 | WRB | Dihydrofolate reductase | 1.5.1.3 | 0.500 | |
| 3dau | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.500 | |
| 1dra | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.499 | |
| 3iro | 2CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.499 | |
| 3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.498 | |
| 1rb3 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.497 | |
| 4elb | 34S | Dihydrofolate reductase | / | 0.496 | |
| 1tdr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.495 | |
| 2qk8 | MTX | Dihydrofolate reductase | / | 0.495 | |
| 3clb | TMQ | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.495 | |
| 4ixg | IXG | Dihydrofolate reductase | 1.5.1.3 | 0.495 | |
| 1daj | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.494 | |
| 3lu8 | IQX | Serum albumin | / | 0.493 | |
| 4rup | H97 | Vitamin D3 receptor A | / | 0.492 | |
| 4x5f | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.492 | |
| 4kjj | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.489 | |
| 1aoe | GW3 | Dihydrofolate reductase | 1.5.1.3 | 0.488 | |
| 3th8 | TH9 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.488 | |
| 3cv9 | VDX | Vitamin D3 dihydroxylase | / | 0.487 | |
| 3dat | MTX | Dihydrofolate reductase | / | 0.487 | |
| 4nc3 | ERM | 5-hydroxytryptamine receptor 2B | / | 0.487 | |
| 3fl9 | TOP | Dihydrofolate reductase | / | 0.486 | |
| 1dyj | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.485 | |
| 1rf7 | DHF | Dihydrofolate reductase | 1.5.1.3 | 0.485 | |
| 2has | C3O | Vitamin D3 receptor | / | 0.485 | |
| 3fwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.485 | |
| 3um6 | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.485 | |
| 4fjy | FJY | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.485 | |
| 3qlr | QLR | Dihydrofolate reductase | 1.5.1.3 | 0.484 | |
| 3p99 | LNP | Lanosterol 14-alpha-demethylase | / | 0.483 | |
| 3qm4 | PN0 | Cytochrome P450 2D6 | / | 0.483 | |
| 4ixf | IXF | Dihydrofolate reductase | 1.5.1.3 | 0.483 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.482 | |
| 1j3k | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.481 | |
| 4bgi | I4I | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.481 | |
| 4elf | 35I | Dihydrofolate reductase | / | 0.481 | |
| 1sej | F89 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.480 | |
| 3zuy | TCH | Transporter | / | 0.480 | |
| 5dq8 | FLF | Transcriptional enhancer factor TEF-4 | / | 0.480 | |
| 1uy7 | PU4 | Heat shock protein HSP 90-alpha | / | 0.479 | |
| 2hb8 | MVD | Vitamin D3 receptor | / | 0.479 | |
| 3um5 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.479 | |
| 4j6b | PLO | Cytochrome P450 monooxygenase | / | 0.479 | |
| 3cd2 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.478 | |
| 3ix9 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.478 | |
| 4o0r | X4Z | Serine/threonine-protein kinase PAK 1 | 2.7.11.1 | 0.478 | |
| 2y98 | MIV | Mycinamicin IV hydroxylase/epoxidase | / | 0.477 | |
| 3sqy | Q11 | Dihydrofolate reductase | 1.5.1.3 | 0.477 | |
| 4elh | 53I | Dihydrofolate reductase | / | 0.477 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.477 | |
| 5itz | LOC | Tubulin beta-2B chain | / | 0.477 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.476 | |
| 2yki | YKI | Heat shock protein HSP 90-alpha | / | 0.476 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.476 | |
| 3rg9 | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.476 | |
| 2fwy | H64 | Heat shock protein HSP 90-alpha | / | 0.475 | |
| 2m56 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.475 | |
| 3ez2 | ADP | Plasmid partition protein A | / | 0.475 | |
| 2hw2 | RFP | Rifampin ADP-ribosyl transferase | / | 0.474 | |
| 2qg2 | A91 | Heat shock protein HSP 90-alpha | / | 0.474 | |
| 3inw | JZB | Heat shock protein HSP 90-alpha | / | 0.474 | |
| 4iui | 1GQ | Estrogen receptor | / | 0.474 | |
| 5eyp | LOC | Tubulin beta chain | / | 0.474 | |
| 1t87 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.473 | |
| 1uy9 | PU6 | Heat shock protein HSP 90-alpha | / | 0.473 | |
| 1uyk | PUX | Heat shock protein HSP 90-alpha | / | 0.473 | |
| 2wuf | KEM | 4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase | 3.7.1.17 | 0.473 | |
| 3d0b | SNX | Heat shock protein HSP 90-alpha | / | 0.473 | |
| 4g8z | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.473 | |
| 1ddr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.472 | |
| 1ly4 | COQ | Dihydrofolate reductase | 1.5.1.3 | 0.472 | |
| 2y46 | MIV | Mycinamicin IV hydroxylase/epoxidase | / | 0.472 | |
| 3kpz | ZNE | Vitamin D3 receptor | / | 0.472 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.472 | |
| 4ia1 | BIV | Vitamin D3 receptor A | / | 0.472 | |
| 4j03 | FVS | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.472 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.471 | |
| 1m13 | HYF | Nuclear receptor subfamily 1 group I member 2 | / | 0.471 | |
| 1m78 | CLZ | Dihydrofolate reductase | 1.5.1.3 | 0.471 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.471 | |
| 2z97 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.471 | |
| 1n4h | REA | Nuclear receptor ROR-beta | / | 0.470 | |
| 1og5 | SWF | Cytochrome P450 2C9 | / | 0.470 | |
| 3o0i | P54 | Heat shock protein HSP 90-alpha | / | 0.470 | |
| 4f1s | F1S | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.470 | |
| 4hw3 | 19G | Induced myeloid leukemia cell differentiation protein Mcl-1 | / | 0.470 | |
| 4v12 | POG | MaoC like domain protein | / | 0.470 | |
| 1dz6 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.469 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.469 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.469 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.469 | |
| 4bii | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.469 | |
| 4fhi | 0S4 | Vitamin D3 receptor A | / | 0.469 | |
| 4l9k | EHF | Serum albumin | / | 0.469 | |
| 4mr6 | 1K0 | Bromodomain-containing protein 2 | / | 0.469 | |
| 1db1 | VDX | Vitamin D3 receptor | / | 0.468 | |
| 1dis | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.468 | |
| 1qzf | FOL | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.468 | |
| 1rek | B8L | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.468 | |
| 1t1r | IMB | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.468 | |
| 2exc | JNK | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.468 | |
| 3fco | IIG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.468 | |
| 3qg2 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.468 | |
| 3s1c | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.468 | |
| 3w0a | DS5 | Vitamin D3 receptor | / | 0.468 | |
| 3zc3 | NAP | Ferredoxin--NADP reductase | 1.18.1.2 | 0.468 | |
| 4fhh | 0U3 | Vitamin D3 receptor A | / | 0.468 | |
| 4fjz | 4FJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.468 | |
| 4hni | 16W | Casein kinase I isoform epsilon | 2.7.11.1 | 0.468 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.468 | |
| 4lcg | 1WM | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.468 | |
| 5hi6 | MTX | Dihydrofolate reductase | / | 0.468 | |
| 1e26 | GPB | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.467 | |
| 3cge | NDP | Coenzyme A disulfide reductase | / | 0.467 | |
| 3hz1 | 42C | Heat shock protein HSP 90-alpha | / | 0.467 | |
| 3nj0 | PYV | Abscisic acid receptor PYL2 | / | 0.467 | |
| 3nrr | D16 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.467 | |
| 4flp | JQ1 | Bromodomain testis-specific protein | / | 0.467 | |
| 4ia2 | BIV | Vitamin D3 receptor A | / | 0.467 | |
| 4l9q | 9TP | Serum albumin | / | 0.467 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.466 | |
| 2ykc | YKC | Heat shock protein HSP 90-alpha | / | 0.466 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.466 | |
| 3inx | JZC | Heat shock protein HSP 90-alpha | / | 0.466 | |
| 3ql3 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
| 4nb6 | 444 | Nuclear receptor ROR-gamma | / | 0.466 | |
| 4r38 | RBF | Blue-light-activated histidine kinase 2 | 2.7.13.3 | 0.466 | |
| 4uyg | 73B | Bromodomain-containing protein 2 | / | 0.466 | |
| 1dhj | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
| 1ly3 | COG | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
| 2hb7 | O1C | Vitamin D3 receptor | / | 0.465 | |
| 3gc9 | B45 | Mitogen-activated protein kinase 11 | 2.7.11.24 | 0.465 | |
| 3sr5 | Q12 | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
| 4a9m | P9M | Bromodomain-containing protein 2 | / | 0.465 | |
| 4alh | A9P | Bromodomain-containing protein 2 | / | 0.465 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 1ict | T44 | Transthyretin | / | 0.464 | |
| 2ykb | YKB | Heat shock protein HSP 90-alpha | / | 0.464 | |
| 2yke | YKE | Heat shock protein HSP 90-alpha | / | 0.464 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 3tqb | FOL | Dihydrofolate reductase | / | 0.464 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.464 | |
| 4o70 | 1QK | Bromodomain-containing protein 4 | / | 0.464 | |
| 5cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.464 | |
| 1ek2 | CDU | Bifunctional epoxide hydrolase 2 | / | 0.463 | |
| 2h55 | DZ8 | Heat shock protein HSP 90-alpha | / | 0.463 | |
| 4bbh | NHW | Glycylpeptide N-tetradecanoyltransferase | / | 0.463 | |
| 1g4s | TPS | Thiamine-phosphate synthase | / | 0.462 | |
| 1ie4 | T44 | Transthyretin | / | 0.462 | |
| 1jio | DEB | 6-deoxyerythronolide B hydroxylase | / | 0.462 | |
| 1uym | PU3 | Heat shock protein HSP 90-beta | / | 0.462 | |
| 1zg3 | 2HI | Isoflavone 4'-O-methyltransferase | / | 0.462 | |
| 2zjw | REF | Casein kinase II subunit alpha | 2.7.11.1 | 0.462 | |
| 3tda | PN0 | Cytochrome P450 2D6 | / | 0.462 | |
| 4awq | 592 | Heat shock protein HSP 90-alpha | / | 0.462 | |
| 4l49 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.462 | |
| 1eny | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.461 | |
| 3r04 | UNQ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.461 | |
| 4a9o | A9O | Bromodomain-containing protein 2 | / | 0.461 | |
| 4iv2 | 1GR | Estrogen receptor | / | 0.461 | |
| 4j0s | 1H3 | Bromodomain-containing protein 4 | / | 0.461 | |
| 4ubs | DIF | Pentalenic acid synthase | 1.14.15.11 | 0.461 | |
| 4ucn | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.461 | |
| 1uy8 | PU5 | Heat shock protein HSP 90-alpha | / | 0.460 | |
| 2ard | FDA | Flavin-dependent tryptophan halogenase PrnA | 1.14.19.9 | 0.460 | |
| 3anl | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.460 | |
| 3fwg | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.460 | |
| 3qlg | 1N1 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.460 | |
| 3s2a | 2NQ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.460 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.460 | |
| 4ez5 | 0RS | Cyclin-dependent kinase 6 | 2.7.11.22 | 0.460 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.460 | |
| 4nkv | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.460 | |
| 1kzj | CB3 | Thymidylate synthase | / | 0.459 | |
| 1qzf | CB3 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.459 | |
| 1t85 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.459 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.459 | |
| 1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.459 | |
| 2wi4 | ZZ4 | Heat shock protein HSP 90-alpha | / | 0.459 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.459 | |
| 3e5a | VX6 | Aurora kinase A | 2.7.11.1 | 0.459 | |
| 3ggg | NAD | Prephenate dehydrogenase | / | 0.459 | |
| 3zux | TCH | Transporter | / | 0.459 | |
| 4in4 | 4ID | Kelch-like ECH-associated protein 1 | / | 0.459 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.459 | |
| 2ghm | LIC | Mitogen-activated protein kinase 14 | / | 0.458 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 2qbl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.458 | |
| 2zaw | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.458 | |
| 3ey9 | TDP | Pyruvate dehydrogenase [ubiquinone] | 1.2.5.1 | 0.458 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.458 | |
| 3opd | HIE | Heat shock protein 83 | / | 0.458 | |
| 3r3f | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.458 | |
| 3t2y | FAD | Sulfide-quinone reductase | / | 0.458 | |
| 3we4 | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.458 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 1dhi | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 1dz4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.457 | |
| 1fml | RTL | Retinol dehydratase | / | 0.457 | |
| 1s19 | MC9 | Vitamin D3 receptor | / | 0.457 | |
| 1s4d | SAH | Uroporphyrinogen-III C-methyltransferase | 2.1.1.107 | 0.457 | |
| 2hc4 | VDX | Vitamin D3 receptor A | / | 0.457 | |
| 3dxj | NE6 | DNA-directed RNA polymerase subunit beta | / | 0.457 | |
| 3dxj | NE6 | DNA-directed RNA polymerase subunit beta' | / | 0.457 | |
| 3q5k | D1U | Heat shock protein 83-1 | / | 0.457 | |
| 4dk5 | 0KO | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.457 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.457 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.457 | |
| 6cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.457 | |
| 1rkh | VD2 | Vitamin D3 receptor | / | 0.456 | |
| 1sn0 | T44 | Transthyretin | / | 0.456 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 2bxe | 1FL | Serum albumin | / | 0.456 | |
| 2vn0 | TDZ | Cytochrome P450 2C8 | / | 0.456 | |
| 3a0i | AJI | Glucokinase | 2.7.1.2 | 0.456 | |
| 3zk5 | Z18 | Cytochrome P450 monooxygenase PikC | / | 0.456 | |
| 4h97 | 53S | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 4hxs | 1A3 | Bromodomain-containing protein 4 | / | 0.456 | |
| 4nh8 | 2LC | Heat shock protein HSP 90-alpha | / | 0.456 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 1ie9 | VDX | Vitamin D3 receptor | / | 0.455 | |
| 2iod | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.455 | |
| 3a78 | 3EV | Vitamin D3 receptor | / | 0.455 | |
| 3czr | 3CZ | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.455 | |
| 3lfc | Z86 | Mitogen-activated protein kinase 14 | / | 0.455 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.455 | |
| 3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.455 | |
| 3qdd | 94M | Heat shock protein HSP 90-alpha | / | 0.455 | |
| 3vtc | TK3 | Vitamin D3 receptor | / | 0.455 | |
| 4fuy | EK2 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.455 | |
| 4ly9 | 1YY | Glucokinase regulatory protein | / | 0.455 | |
| 4mxx | DB8 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.455 | |
| 1yin | CM3 | Estrogen receptor | / | 0.454 | |
| 1ykr | 628 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
| 2fwz | H71 | Heat shock protein HSP 90-alpha | / | 0.454 | |
| 2o4r | VD5 | Vitamin D3 receptor | / | 0.454 | |
| 2vwu | 7X1 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.454 | |
| 2vwy | 7X5 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.454 | |
| 2wi7 | 2KL | Heat shock protein HSP 90-alpha | / | 0.454 | |
| 3c0g | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.454 | |
| 3ft8 | MOJ | Heat shock protein HSP 90-alpha | / | 0.454 | |
| 3ruk | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.454 | |
| 3sp9 | IL2 | Peroxisome proliferator-activated receptor delta | / | 0.454 | |
| 3tea | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.454 | |
| 4ib4 | ERM | 5-hydroxytryptamine receptor 2B | / | 0.454 | |
| 4lt6 | 3AT | Poly(A) polymerase gamma | 2.7.7.19 | 0.454 | |
| 1ia3 | TQ5 | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.453 | |
| 2feu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.453 | |
| 2i1v | ADP | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 | 2.7.1.105 | 0.453 | |
| 2xls | FAD | Putative flavin-containing monooxygenase | / | 0.453 | |
| 2ykj | YKJ | Heat shock protein HSP 90-alpha | / | 0.453 | |
| 3hz1 | 37D | Heat shock protein HSP 90-alpha | / | 0.453 | |
| 3ue4 | DB8 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.453 | |
| 3w0y | DS4 | Vitamin D3 receptor | / | 0.453 | |
| 4g21 | 0VP | Vitamin D3 receptor A | / | 0.453 | |
| 4inb | 1F6 | Gag protein | / | 0.453 | |
| 4l4c | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.453 | |
| 4rlh | 0WE | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.453 | |
| 4uyf | 73B | Bromodomain-containing protein 2 | / | 0.453 | |
| 1e7v | LY2 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.452 | |
| 1hfp | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1lco | PPY | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.452 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.452 | |
| 1t88 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 2bbq | PFG | Thymidylate synthase | / | 0.452 | |
| 2pr2 | DG1 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.452 | |
| 2wd9 | IBP | Acyl-coenzyme A synthetase ACSM2A, mitochondrial | 6.2.1.2 | 0.452 | |
| 2yek | EAM | Bromodomain-containing protein 2 | / | 0.452 | |
| 2yem | WSH | Bromodomain-containing protein 4 | / | 0.452 | |
| 3jzi | JZL | Biotin carboxylase | 6.3.4.14 | 0.452 | |
| 3koo | 24D | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.452 | |
| 4b7s | QLE | Cytochrome P450 monooxygenase PikC | / | 0.452 | |
| 4bkz | 1WS | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.452 | |
| 4h50 | NAP | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.452 | |
| 4jib | 1L6 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.452 | |
| 4mfb | 29T | Gag-Pol polyprotein | 2.7.7.49 | 0.452 | |
| 2bxm | IMN | Serum albumin | / | 0.451 | |
| 2cig | 1DG | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 2hm9 | TRR | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 2tsc | CB3 | Thymidylate synthase | / | 0.451 | |
| 2ze2 | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.451 | |
| 3a1l | 2CC | Cytochrome P450 | / | 0.451 | |
| 3jzf | JZK | Biotin carboxylase | 6.3.4.14 | 0.451 | |
| 3s79 | ASD | Aromatase | 1.14.14.14 | 0.451 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.451 | |
| 4bge | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.451 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.451 | |
| 1i7i | AZ2 | Peroxisome proliferator-activated receptor gamma | / | 0.450 | |
| 1jip | KTN | 6-deoxyerythronolide B hydroxylase | / | 0.450 | |
| 1xuo | LA1 | Integrin alpha-L | / | 0.450 | |
| 1y57 | MPZ | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.450 | |
| 2chw | 039 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.450 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.450 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.450 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 3iqz | H4M | F420-dependent methylenetetrahydromethanopterin dehydrogenase | 1.5.98.1 | 0.450 | |
| 3l63 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 3mqe | 416 | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.450 | |
| 3q30 | D61 | Squalene synthase | 2.5.1.21 | 0.450 | |
| 3vt6 | 5YI | Vitamin D3 receptor | / | 0.450 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 4dp3 | MMV | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.450 | |
| 4eft | EFT | Heat shock protein HSP 90-alpha | / | 0.450 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.450 | |
| 4j4v | SVR | Nucleocapsid protein | / | 0.450 | |
| 4u0o | MTA | Lipoyl synthase 2 | / | 0.450 | |
| 1guf | NDP | Enoyl-[acyl-carrier-protein] reductase 1, mitochondrial | 1.3.1.10 | 0.449 | |
| 1iyz | NDP | Probable quinone oxidoreductase | / | 0.449 | |
| 1j3j | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.449 | |
| 1m7a | MQU | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1syn | F89 | Thymidylate synthase | / | 0.449 | |
| 1uyc | PU7 | Heat shock protein HSP 90-alpha | / | 0.449 | |
| 1v9a | SAH | Uncharacterized protein | / | 0.449 | |
| 1zmc | NAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.449 | |
| 2phk | ATP | Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform | 2.7.11.19 | 0.449 | |
| 2q59 | 240 | Peroxisome proliferator-activated receptor gamma | / | 0.449 | |
| 2vwx | 7X4 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.449 | |
| 2wtc | VGM | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.449 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.449 | |
| 3hz5 | Z64 | Heat shock protein HSP 90-alpha | / | 0.449 | |
| 3zhq | TPP | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.449 | |
| 3zsh | 469 | Mitogen-activated protein kinase 14 | / | 0.449 | |
| 4awo | 99B | Heat shock protein HSP 90-alpha | / | 0.449 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.449 | |
| 4lrg | 1XB | Bromodomain-containing protein 4 | / | 0.449 | |
| 5jqb | IBP | Envelope glycoprotein | / | 0.449 | |
| 3rfm | CFF | Adenosine receptor A2a | / | 0.449 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.448 | |
| 1rk3 | VDX | Vitamin D3 receptor | / | 0.448 | |
| 1txi | TX5 | Vitamin D3 receptor | / | 0.448 | |
| 1yw2 | PGJ | Mitogen-activated protein kinase 14 | / | 0.448 | |
| 2aqi | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.448 | |
| 2nnh | REA | Cytochrome P450 2C8 | / | 0.448 | |
| 2w4i | VGA | Glutamate racemase | / | 0.448 | |
| 2wsa | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.448 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 2zax | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 3eig | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.448 | |
| 3iqe | F42 | F420-dependent methylenetetrahydromethanopterin dehydrogenase | 1.5.98.1 | 0.448 | |
| 3kpk | FAD | Sulfide-quinone reductase | / | 0.448 | |
| 3m7r | VDX | Vitamin D3 receptor | / | 0.448 | |
| 3nr4 | PYV | Abscisic acid receptor PYL2 | / | 0.448 | |
| 3ns2 | PYV | Abscisic acid receptor PYL2 | / | 0.448 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.448 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.448 | |
| 4ek1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 4o76 | 1M3 | Bromodomain-containing protein 4 | / | 0.448 | |
| 5g3t | FDA | Flavin-dependent L-tryptophan oxidase VioA | / | 0.448 | |
| 1dhf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1ezf | IN0 | Squalene synthase | 2.5.1.21 | 0.447 | |
| 1jm6 | ADP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial | 2.7.11.2 | 0.447 | |
| 1kij | NOV | DNA gyrase subunit B | / | 0.447 | |
| 1rx8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1xqc | AEJ | Estrogen receptor | / | 0.447 | |
| 1yrd | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 1z1f | STL | Resveratrol synthase | / | 0.447 | |
| 1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.447 | |
| 2cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 2y30 | SM8 | Putative repressor SimReg2 | / | 0.447 | |
| 2yee | 2EC | Heat shock protein HSP 90-alpha | / | 0.447 | |
| 2znn | S44 | Peroxisome proliferator-activated receptor alpha | / | 0.447 | |
| 3a8w | ATP | Protein kinase C iota type | 2.7.11.13 | 0.447 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.447 | |
| 3vjh | J35 | Peroxisome proliferator-activated receptor gamma | / | 0.447 | |
| 3vtb | TKA | Vitamin D3 receptor | / | 0.447 | |
| 4b11 | NHW | Glycylpeptide N-tetradecanoyltransferase | / | 0.447 | |
| 4gb9 | 0WR | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.447 | |
| 4i1n | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 4lch | 1WN | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.447 | |
| 4o71 | CPB | Bromodomain-containing protein 4 | / | 0.447 | |
| 1drb | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1e90 | MYC | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.446 | |
| 1iid | NHM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.446 | |
| 1mc5 | AHE | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.446 | |
| 1nq7 | ARL | Nuclear receptor ROR-beta | / | 0.446 | |
| 1o76 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 1pp9 | SMA | Cytochrome b | / | 0.446 | |
| 1rx7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 2fsz | OHT | Estrogen receptor beta | / | 0.446 | |
| 2iya | ZIO | Oleandomycin glycosyltransferase | / | 0.446 | |
| 2j0d | ERY | Cytochrome P450 3A4 | / | 0.446 | |
| 2jn3 | JN3 | Fatty acid-binding protein, liver | / | 0.446 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 2vxo | XMP | GMP synthase [glutamine-hydrolyzing] | 6.3.5.2 | 0.446 | |
| 2w2l | NAD | D-mandelate dehydrogenase | / | 0.446 | |
| 2yei | XQI | Heat shock protein HSP 90-alpha | / | 0.446 | |
| 2zl9 | VDA | Vitamin D3 receptor | / | 0.446 | |
| 3a1n | NAD | NDP-sugar epimerase | / | 0.446 | |
| 3d80 | Q22 | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 3iw8 | HIZ | Mitogen-activated protein kinase 14 | / | 0.446 | |
| 3l3r | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 4bmp | FMN | Protein NrdI | / | 0.446 | |
| 4cgp | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.446 | |
| 4gg7 | 0J8 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.446 | |
| 4i3w | NAD | Aldehyde dehydrogenase (NAD+) | / | 0.446 | |
| 4o1m | NAD | Enoyl-acyl carrier reductase | / | 0.446 | |
| 4o95 | 245 | Cytokinin dehydrogenase 4 | / | 0.446 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.446 | |
| 4z1f | H71 | Heat shock protein 75 kDa, mitochondrial | / | 0.446 | |
| 5hs1 | VOR | Lanosterol 14-alpha demethylase | / | 0.446 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.445 | |
| 1iwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 1kmv | LII | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 1sn5 | T3 | Transthyretin | / | 0.445 | |
| 1uyh | PU0 | Heat shock protein HSP 90-alpha | / | 0.445 | |
| 2gtk | 208 | Peroxisome proliferator-activated receptor gamma | / | 0.445 | |
| 2o4j | VD4 | Vitamin D3 receptor | / | 0.445 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.445 | |
| 2tps | TPS | Thiamine-phosphate synthase | / | 0.445 | |
| 2vwz | 7X6 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.445 | |
| 3a14 | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.445 | |
| 3gob | HXX | DdmC | / | 0.445 | |
| 3lj3 | WYE | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.445 | |
| 3meg | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.445 | |
| 3neg | PYV | Abscisic acid receptor PYL1 | / | 0.445 | |
| 3of2 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.445 | |
| 3r32 | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.445 | |
| 3t2k | FAD | Sulfide-quinone reductase | / | 0.445 | |
| 3wow | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.445 | |
| 4bew | CZA | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.445 | |
| 4bfr | J82 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform | 2.7.1.153 | 0.445 | |
| 4cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 4dhy | S41 | Glucokinase | 2.7.1.2 | 0.445 | |
| 4e37 | NDP | Catalase | 1.11.1.6 | 0.445 | |
| 4jq8 | KJ8 | Epidermal growth factor receptor | 2.7.10.1 | 0.445 | |
| 4p6w | MOF | Glucocorticoid receptor | / | 0.445 | |
| 4x5i | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.445 | |
| 1e6e | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.444 | |
| 1knu | YPA | Peroxisome proliferator-activated receptor gamma | / | 0.444 | |
| 1lsj | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.444 | |
| 1phg | MYT | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 1rd7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1rg7 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1yhs | STU | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.444 | |
| 1zid | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.444 | |
| 2bj4 | OHT | Estrogen receptor | / | 0.444 | |
| 2chx | 090 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.444 | |
| 2j14 | GNI | Peroxisome proliferator-activated receptor delta | / | 0.444 | |
| 2nmt | NHM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.444 | |
| 2w6o | OA3 | Biotin carboxylase | 6.3.4.14 | 0.444 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.444 | |
| 3lak | KR1 | Gag-Pol polyprotein | 2.7.7.49 | 0.444 | |
| 3mnr | SD1 | Heat shock protein HSP 90-alpha | / | 0.444 | |
| 3nwy | GTP | Uridylate kinase | / | 0.444 | |
| 3oqf | S51 | Renin | 3.4.23.15 | 0.444 | |
| 3syi | FAD | Sulfide-quinone reductase | / | 0.444 | |
| 3ttj | JBI | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.444 | |
| 4b12 | NHW | Glycylpeptide N-tetradecanoyltransferase | / | 0.444 | |
| 4dgn | LU2 | Casein kinase II subunit alpha | 2.7.11.1 | 0.444 | |
| 4g3r | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 4m6l | 21V | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 4ma6 | 28E | Ara h 8 allergen | / | 0.444 | |
| 4ruo | BIV | Vitamin D3 receptor A | / | 0.444 | |
| 4ryv | ZEA | Protein LlR18A | / | 0.444 | |
| 4wa9 | AXI | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.444 | |
| 4yt5 | H4M | H(2)-forming methylenetetrahydromethanopterin dehydrogenase-related protein MJ1338 | / | 0.444 | |
| 5c8y | ACP | Tubulin tyrosine ligase | / | 0.444 | |
| 1sj0 | E4D | Estrogen receptor | / | 0.443 | |
| 1uye | PU9 | Heat shock protein HSP 90-alpha | / | 0.443 | |
| 1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.443 | |
| 2a1n | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 2har | OCC | Vitamin D3 receptor | / | 0.443 | |
| 2hnz | PC0 | Gag-Pol polyprotein | 2.7.7.49 | 0.443 | |
| 2jf9 | OHT | Estrogen receptor | / | 0.443 | |
| 2ovm | AS0 | Progesterone receptor | / | 0.443 | |
| 2ww4 | ADP | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | 2.7.1.148 | 0.443 | |
| 3bfb | 9OD | Pheromone-binding protein ASP1 | / | 0.443 | |
| 3fwf | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 3gc8 | B45 | Mitogen-activated protein kinase 11 | 2.7.11.24 | 0.443 | |
| 3pe6 | ZYH | Monoglyceride lipase | / | 0.443 | |
| 3qaq | QAQ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.443 | |
| 3vso | EK1 | Peroxisome proliferator-activated receptor gamma | / | 0.443 | |
| 3w0r | ANP | Hygromycin-B 4-O-kinase | 2.7.1.163 | 0.443 | |
| 4c66 | H4C | Bromodomain-containing protein 4 | / | 0.443 | |
| 4dpu | AGS | Mevalonate diphosphate decarboxylase | / | 0.443 | |
| 4egn | TWO | Cytochrome P450 | / | 0.443 | |
| 4fex | 0TO | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.443 | |
| 4ge4 | 0KE | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.443 | |
| 4ge7 | 0K5 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.443 | |
| 4itf | TFY | Vitamin D3 receptor | / | 0.443 | |
| 4jlj | 1NM | Deoxycytidine kinase | 2.7.1.74 | 0.443 | |
| 4kba | 1QM | Casein kinase I isoform delta | 2.7.11.1 | 0.443 | |
| 1t2b | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.442 | |
| 1uyd | PU8 | Heat shock protein HSP 90-alpha | / | 0.442 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.442 | |
| 2bl9 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.442 | |
| 2w0b | CMW | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.442 | |
| 2ydw | WSH | Bromodomain-containing protein 2 | / | 0.442 | |
| 3ac1 | KZI | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.442 | |
| 3c6t | M14 | Gag-Pol polyprotein | 2.7.7.49 | 0.442 | |
| 3fzn | D7K | Benzoylformate decarboxylase | 4.1.1.7 | 0.442 | |
| 3lan | KBT | Gag-Pol polyprotein | 2.7.7.49 | 0.442 | |
| 3ofm | 4B0 | Casein kinase II subunit alpha' | 2.7.11.1 | 0.442 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.442 | |
| 4anv | 751 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.442 | |
| 4b7d | QLE | Cytochrome P450 monooxygenase PikC | / | 0.442 | |
| 4b8z | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.442 | |
| 4bqp | VMY | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 4c2y | MYA | Glycylpeptide N-tetradecanoyltransferase 1 | / | 0.442 | |
| 4czt | CPS | CBL-interacting serine/threonine-protein kinase 23 | 2.7.11.1 | 0.442 | |
| 4eil | FOL | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.442 | |
| 4ez8 | DHF | Thymidylate synthase | 2.1.1.45 | 0.442 | |
| 4fhb | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 5f1c | ATP | Uncharacterized protein | / | 0.442 | |
| 1cjk | FOK | Adenylate cyclase type 2 | / | 0.441 | |
| 1cjk | FOK | Adenylate cyclase type 5 | / | 0.441 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.441 | |
| 1enz | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.441 | |
| 1ywr | LI9 | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.441 | |
| 2ewa | SB2 | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 2pul | ACP | Methylthioribose kinase | 2.7.1.100 | 0.441 | |
| 2ync | YNC | Glycylpeptide N-tetradecanoyltransferase | / | 0.441 | |
| 2zla | VDB | Vitamin D3 receptor | / | 0.441 | |
| 2zui | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 3g45 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.441 | |
| 3i1f | GCP | Translation initiation factor 2 subunit gamma | / | 0.441 | |
| 3ict | ADP | Coenzyme A disulfide reductase | / | 0.441 | |
| 3lu7 | IPX | Serum albumin | / | 0.441 | |
| 3swr | SFG | DNA (cytosine-5)-methyltransferase 1 | 2.1.1.37 | 0.441 | |
| 3tmz | 06X | Cytochrome P450 2B4 | 1.14.14.1 | 0.441 | |
| 3tqh | NDP | Quinone oxidoreductase | / | 0.441 | |
| 3w0c | 6DS | Vitamin D3 receptor | / | 0.441 | |
| 4bqg | 50Q | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 4efu | EFU | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 4ite | TEY | Vitamin D3 receptor | / | 0.441 | |
| 4ku5 | DCC | 3-oxoacyl-[ACP] synthase III | / | 0.441 | |
| 4o2b | LOC | Tubulin beta-2B chain | / | 0.441 | |
| 5d1b | TSN | Histone deacetylase 8 | 3.5.1.98 | 0.441 | |
| 1s3y | TQT | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1uyf | PU1 | Heat shock protein HSP 90-alpha | / | 0.440 | |
| 1yrc | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 2cd8 | PXI | Cytochrome P450 monooxygenase PikC | / | 0.440 | |
| 2j9g | ANP | Biotin carboxylase | 6.3.4.14 | 0.440 | |
| 2oax | SNL | Mineralocorticoid receptor | / | 0.440 | |
| 2pun | ACP | Methylthioribose kinase | 2.7.1.100 | 0.440 | |
| 3bgq | VX2 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.440 | |
| 3f8k | COA | Uncharacterized protein | / | 0.440 | |
| 3hf6 | LX0 | Tryptophan 5-hydroxylase 1 | 1.14.16.4 | 0.440 | |
| 3ibd | CPZ | Cytochrome P450 2B6 | 1.14.13 | 0.440 | |
| 3mee | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.440 | |
| 3ntz | 3TZ | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 3sz0 | FAD | Sulfide-quinone reductase | / | 0.440 | |
| 3t14 | FAD | Sulfide-quinone reductase | / | 0.440 | |
| 3u8h | BHP | Phospholipase A2, membrane associated | / | 0.440 | |
| 3ump | ATP | ATP-dependent 6-phosphofructokinase isozyme 2 | 2.7.1.11 | 0.440 | |
| 3zbn | COA | 3-ketoacyl-CoA thiolase-like protein | / | 0.440 | |
| 4akn | S5B | Bromodomain-containing protein 2 | / | 0.440 | |
| 4eh9 | IRG | Mitogen-activated protein kinase 14 | / | 0.440 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.440 | |
| 4hvb | 19P | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 4ig3 | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.440 | |
| 4l8u | 9AZ | Serum albumin | / | 0.440 | |
| 5ack | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.440 | |
| 5c8w | PCG | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.440 | |
| 4z9g | 1Q5 | Corticotropin-releasing factor receptor 1 | / | 0.440 |