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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3l1sZ92Glycogen synthase kinase-3 beta2.7.11.26

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3l1sZ92Glycogen synthase kinase-3 beta2.7.11.261.000
4acdGR9Glycogen synthase kinase-3 beta2.7.11.260.619
4acg6LQGlycogen synthase kinase-3 beta2.7.11.260.619
4achKDIGlycogen synthase kinase-3 beta2.7.11.260.616
4acc7YGGlycogen synthase kinase-3 beta2.7.11.260.601
4afjSJJGlycogen synthase kinase-3 beta2.7.11.260.596
4dit0KDGlycogen synthase kinase-3 beta2.7.11.260.589
3i4bZ48Glycogen synthase kinase-3 beta2.7.11.260.587
1q41IXMGlycogen synthase kinase-3 beta2.7.11.260.586
3gb2G3BGlycogen synthase kinase-3 beta2.7.11.260.578
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.568
1uv5BRWGlycogen synthase kinase-3 beta2.7.11.260.566
3du8553Glycogen synthase kinase-3 beta2.7.11.260.566
3f883HTGlycogen synthase kinase-3 beta2.7.11.260.561
1pyxANPGlycogen synthase kinase-3 beta2.7.11.260.556
4b7tCWTGlycogen synthase kinase-3 beta2.7.11.260.548
3f7z34OGlycogen synthase kinase-3 beta2.7.11.260.539
4hyi1AOSerine/threonine-protein kinase Chk12.7.11.10.527
4utdACPAurora kinase A2.7.11.10.526
2c3kABOSerine/threonine-protein kinase Chk12.7.11.10.524
3sd0TSKGlycogen synthase kinase-3 beta2.7.11.260.523
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.522
1j1cADPGlycogen synthase kinase-3 beta2.7.11.260.520
2broDF2Serine/threonine-protein kinase Chk12.7.11.10.519
4dfn0K1Tyrosine-protein kinase SYK2.7.10.20.518
4j1rI5RGlycogen synthase kinase-3 beta2.7.11.260.517
4l521ULMitogen-activated protein kinase kinase kinase 72.7.11.250.517
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.516
5drdATPAurora kinase A2.7.11.10.516
5dt4ATPAurora kinase A2.7.11.10.516
4ftiH7KSerine/threonine-protein kinase Chk12.7.11.10.515
2pvnP63Casein kinase II subunit alpha2.7.11.10.514
1r0eDFNGlycogen synthase kinase-3 beta2.7.11.260.513
1q3wATUGlycogen synthase kinase-3 beta2.7.11.260.511
4ftkH9KSerine/threonine-protein kinase Chk12.7.11.10.511
1mq4ADPAurora kinase A2.7.11.10.510
2hog710Serine/threonine-protein kinase Chk12.7.11.10.510
4bgg844Activin receptor type-12.7.11.300.510
4yzcSTUSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.510
5dr9SKEAurora kinase A2.7.11.10.510
1q5kTMUGlycogen synthase kinase-3 beta2.7.11.260.509
4c02TAKActivin receptor type-12.7.11.300.507
4ftu7HKSerine/threonine-protein kinase Chk12.7.11.10.507
4nm0ADPGlycogen synthase kinase-3 beta2.7.11.260.507
3mfsANPPeripheral plasma membrane protein CASK2.7.11.10.506
4dymIYZActivin receptor type-12.7.11.300.506
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.505
4dgmAGICasein kinase II subunit alpha2.7.11.10.503
2dwbANPAurora kinase A2.7.11.10.502
3jxwLXGSerine/threonine-protein kinase pim-12.7.11.10.502
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.502
4idtT28Mitogen-activated protein kinase kinase kinase 142.7.11.250.502
4jbpYPHAurora kinase A2.7.11.10.502
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.501
3q3b55EGlycogen synthase kinase-3 beta2.7.11.260.501
4hyh1AMSerine/threonine-protein kinase Chk12.7.11.10.501
4fob0USALK tyrosine kinase receptor2.7.10.10.500
1q3dSTUGlycogen synthase kinase-3 beta2.7.11.260.499
4jia1K3Tyrosine-protein kinase JAK2/0.499
3r2b05BMAP kinase-activated protein kinase 22.7.11.10.498
4gmy0X5Tyrosine-protein kinase JAK2/0.498
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.497
4bchT7ZCyclin-dependent kinase 92.7.11.220.497
5dosATPAurora kinase A2.7.11.10.497
1u8vFAD4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase/0.496
3k5uPFQAurora kinase A2.7.11.10.496
1ol5ADPAurora kinase A2.7.11.10.495
1q4l679Glycogen synthase kinase-3 beta2.7.11.260.495
3oom507Activin receptor type-12.7.11.300.495
3zrkZRKGlycogen synthase kinase-3 beta2.7.11.260.495
4dn5AGSMitogen-activated protein kinase kinase kinase 142.7.11.250.495
4fyn0VETyrosine-protein kinase SYK2.7.10.20.495
4hvg19QTyrosine-protein kinase JAK32.7.10.20.495
4i22IREEpidermal growth factor receptor2.7.10.10.495
4lm5Q17Serine/threonine-protein kinase pim-12.7.11.10.495
3ckxSTUSerine/threonine-protein kinase 242.7.11.10.494
3hrfATP3-phosphoinositide-dependent protein kinase 12.7.11.10.494
4jqeANPCasein kinase II subunit alpha2.7.11.10.494
1o6yACPSerine/threonine-protein kinase PknB2.7.11.10.493
2cdz23DSerine/threonine-protein kinase PAK 42.7.11.10.493
4j711JXGlycogen synthase kinase-3 beta2.7.11.260.493
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.493
2h96893Mitogen-activated protein kinase 82.7.11.240.492
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.492
4ftm1HKSerine/threonine-protein kinase Chk12.7.11.10.492
5e8xSTUTGF-beta receptor type-12.7.11.300.492
4deeADPAurora kinase A2.7.11.10.491
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.491
5dt3ATPAurora kinase A2.7.11.10.490
2xneASHAurora kinase A2.7.11.10.489
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.489
4e4m0NHTyrosine-protein kinase JAK2/0.489
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.488
3f69XDRSerine/threonine-protein kinase PknB2.7.11.10.488
3i60E86Mitogen-activated protein kinase 12.7.11.240.488
4jbqVX6Aurora kinase A2.7.11.10.488
4qpmADPMitotic checkpoint serine/threonine-protein kinase BUB12.7.11.10.488
1nvrSTUSerine/threonine-protein kinase Chk12.7.11.10.487
2j0m4STFocal adhesion kinase 12.7.10.20.487
3eb0DRKUncharacterized protein/0.487
3pjcPJCTyrosine-protein kinase JAK32.7.10.20.487
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.487
3zrmZRMGlycogen synthase kinase-3 beta2.7.11.260.487
4bibIEOMitogen-activated protein kinase kinase kinase 52.7.11.250.487
4o0wADNAurora kinase A2.7.11.10.487
1bygSTUTyrosine-protein kinase CSK/0.486
1dawANPCasein kinase II subunit alpha2.7.11.10.486
2pvhP19Casein kinase II subunit alpha2.7.11.10.486
2qhm7CSSerine/threonine-protein kinase Chk12.7.11.10.486
3gxlQIGTGF-beta receptor type-12.7.11.300.486
4oauADP2-5A-dependent ribonuclease3.1.260.486
4bidIE8Mitogen-activated protein kinase kinase kinase 52.7.11.250.485
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.485
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.485
4jboWPHAurora kinase A2.7.11.10.485
5e8wSTUTGF-beta receptor type-12.7.11.300.485
1pkdUCNCyclin-dependent kinase 22.7.11.220.484
2ym6YM6Serine/threonine-protein kinase Chk12.7.11.10.484
3emg685Tyrosine-protein kinase SYK2.7.10.20.484
4fg7ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.484
4fstHK4Serine/threonine-protein kinase Chk12.7.11.10.484
4jajXU1Aurora kinase A2.7.11.10.484
1zys199Serine/threonine-protein kinase Chk12.7.11.10.483
2iw84SPCyclin-dependent kinase 22.7.11.220.483
3t113T1Gag-Pol polyprotein3.4.23.160.483
2cchATPCyclin-dependent kinase 22.7.11.220.482
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.482
2gcdSTUSerine/threonine-protein kinase TAO22.7.11.10.482
3mtfA3FActivin receptor type-12.7.11.300.482
3t8oATPRhodopsin kinase/0.482
4ftaH5KSerine/threonine-protein kinase Chk12.7.11.10.482
1eioGCHGastrotropin/0.481
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.481
4idv13VMitogen-activated protein kinase kinase kinase 142.7.11.250.481
4u9aSTUInterleukin-1 receptor-associated kinase 42.7.11.10.481
4wsqKSAAP2-associated protein kinase 12.7.11.10.481
1h1r6CPCyclin-dependent kinase 22.7.11.220.480
2xchCKG3-phosphoinositide-dependent protein kinase 12.7.11.10.480
3cy2MB9Serine/threonine-protein kinase pim-12.7.11.10.480
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.480
4fl1ANPTyrosine-protein kinase SYK2.7.10.20.480
4fod0UVALK tyrosine kinase receptor2.7.10.10.480
4kikKSAInhibitor of nuclear factor kappa-B kinase subunit beta2.7.11.100.480
4qmzB49Serine/threonine-protein kinase 242.7.11.10.480
1qcfPP1Tyrosine-protein kinase HCK2.7.10.20.479
2gdo12CSerine/threonine-protein kinase Chk12.7.11.10.479
2xj1XJ1Serine/threonine-protein kinase pim-12.7.11.10.479
3c0g3AMPeripheral plasma membrane protein CASK2.7.11.10.479
4aguD15Cyclin-dependent kinase-like 1/0.479
4fv6E57Mitogen-activated protein kinase 12.7.11.240.479
4o0sADNAurora kinase A2.7.11.10.479
1oi9N20Cyclin-dependent kinase 22.7.11.220.478
2h8hH8HProto-oncogene tyrosine-protein kinase Src2.7.10.20.478
3mdvCL6Cholesterol 24-hydroxylase/0.478
4enhFVXCholesterol 24-hydroxylase/0.478
2r64740Cyclin-dependent kinase 22.7.11.220.477
2w05FRTCyclin-dependent kinase 22.7.11.220.477
3zh8C58Protein kinase C iota type2.7.11.130.477
1di8DTQCyclin-dependent kinase 22.7.11.220.476
1yhsSTUSerine/threonine-protein kinase pim-12.7.11.10.476
2itqITQEpidermal growth factor receptor2.7.10.10.476
2w1fL0FAurora kinase A2.7.11.10.476
2x2lX2LProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.476
1j1bANPGlycogen synthase kinase-3 beta2.7.11.260.475
1ol6ATPAurora kinase A2.7.11.10.475
2vuw5IDSerine/threonine-protein kinase haspin2.7.11.10.475
2x8eX8ESerine/threonine-protein kinase Chk12.7.11.10.475
3efwAK8Aurora kinase A2.7.11.10.475
3vw6IM6Mitogen-activated protein kinase kinase kinase 52.7.11.250.475
4b0gVEKAurora kinase A2.7.11.10.475
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.475
4ft0HK9Serine/threonine-protein kinase Chk12.7.11.10.475
4hvi19STyrosine-protein kinase JAK32.7.10.20.475
4j97ACPFibroblast growth factor receptor 2/0.475
4qmySTUSerine/threonine-protein kinase 242.7.11.10.475
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.474
1u54ACPActivated CDC42 kinase 1/0.474
2ydiYDISerine/threonine-protein kinase Chk12.7.11.10.474
4bieIE6Mitogen-activated protein kinase kinase kinase 52.7.11.250.474
4dfl0K0Tyrosine-protein kinase SYK2.7.10.20.474
4hvh19RTyrosine-protein kinase JAK32.7.10.20.474
4xuhSFIPeroxisome proliferator-activated receptor gamma/0.474
2ivuZD6Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.473
2xikJ60Serine/threonine-protein kinase 252.7.11.10.473
2xru400Aurora kinase A2.7.11.10.473
3gc8B45Mitogen-activated protein kinase 112.7.11.240.473
3ttiKBIMitogen-activated protein kinase 102.7.11.240.473
4ix6ADPUncharacterized protein/0.473
5dnrATPAurora kinase A2.7.11.10.473
2p33J07Mitogen-activated protein kinase 102.7.11.240.472
2vu3LZECyclin-dependent kinase 22.7.11.220.472
2xvdAS6Ephrin type-B receptor 42.7.10.10.472
3be9P04Casein kinase II subunit alpha2.7.11.10.472
4fsuHK5Serine/threonine-protein kinase Chk12.7.11.10.472
4ft9H4KSerine/threonine-protein kinase Chk12.7.11.10.472
2ow3BIMGlycogen synthase kinase-3 beta2.7.11.260.471
2wmxZY6Serine/threonine-protein kinase Chk12.7.11.10.471
2xngA0HAurora kinase A2.7.11.10.471
2zdt46CMitogen-activated protein kinase 102.7.11.240.471
3a60STURibosomal protein S6 kinase beta-12.7.11.10.471
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.471
3uo50BXAurora kinase A2.7.11.10.471
4bfmANPMaternal embryonic leucine zipper kinase2.7.11.10.471
4c62XWWTyrosine-protein kinase JAK2/0.471
4j95ACPFibroblast growth factor receptor 2/0.471
1nxkSTUMAP kinase-activated protein kinase 22.7.11.10.470
1pmn984Mitogen-activated protein kinase 102.7.11.240.470
2ivvPP1Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.470
3c7qXINVascular endothelial growth factor receptor 22.7.10.10.470
3zdiUGJGlycogen synthase kinase-3 beta2.7.11.260.470
4bl1ANPMaternal embryonic leucine zipper kinase2.7.11.10.470
4erwSTUCyclin-dependent kinase 22.7.11.220.470
4fswHK6Serine/threonine-protein kinase Chk12.7.11.10.470
5dn3ATPAurora kinase A2.7.11.10.470
2bikBI1Serine/threonine-protein kinase pim-12.7.11.10.469
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.469
2xm9LWHSerine/threonine-protein kinase Chk22.7.11.10.469
3l8p0CEAngiopoietin-1 receptor2.7.10.10.469
3vf80JETyrosine-protein kinase SYK2.7.10.20.469
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.469
4gh2HK0Serine/threonine-protein kinase Chk12.7.11.10.469
4n702HXSerine/threonine-protein kinase pim-12.7.11.10.469
4qmpDKISerine/threonine-protein kinase 242.7.11.10.469
2brbPFQSerine/threonine-protein kinase Chk12.7.11.10.468
2c3lIDZSerine/threonine-protein kinase Chk12.7.11.10.468
3c4eC4ESerine/threonine-protein kinase pim-12.7.11.10.468
3lfqA28Cyclin-dependent kinase 22.7.11.220.468
3qcy3Q33-phosphoinositide-dependent protein kinase 12.7.11.10.468
3rmf20ZCyclin-dependent kinase 22.7.11.220.468
4aw1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.468
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.468
2c5nCK8Cyclin-dependent kinase 22.7.11.220.467
2po7CHDFerrochelatase, mitochondrial4.99.1.10.467
2wmqZYQSerine/threonine-protein kinase Chk12.7.11.10.467
2wtcVGMSerine/threonine-protein kinase Chk22.7.11.10.467
3vf9477Tyrosine-protein kinase SYK2.7.10.20.467
4bbe3O4Tyrosine-protein kinase JAK2/0.467
4i0s1B5Tyrosine-protein kinase SYK2.7.10.20.467
4qnyANPMitogen activated protein kinase, putative/0.467
2bdf24AProto-oncogene tyrosine-protein kinase Src2.7.10.20.466
2j9mPY8Cyclin-dependent kinase 22.7.11.220.466
2w0jZATSerine/threonine-protein kinase Chk22.7.11.10.466
2ycsNXPSerine/threonine-protein kinase Chk22.7.11.10.466
3gubGUBDeath-associated protein kinase 12.7.11.10.466
4a06ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.466
4eok4SPCyclin-dependent kinase 22.7.11.220.466
4k110J9Proto-oncogene tyrosine-protein kinase Src2.7.10.20.466
1yi3LY2Serine/threonine-protein kinase pim-12.7.11.10.465
2excJNKMitogen-activated protein kinase 102.7.11.240.465
3dtcVINMitogen-activated protein kinase kinase kinase 92.7.11.250.465
3sheI85MAP kinase-activated protein kinase 32.7.11.10.465
3tucFPWTyrosine-protein kinase SYK2.7.10.20.465
3uli1N3Cyclin-dependent kinase 22.7.11.220.465
3zc6VFCTyrosine-protein kinase JAK32.7.10.20.465
4fkv61KCyclin-dependent kinase 22.7.11.220.465
5ajqDB8Serine/threonine-protein kinase 102.7.11.10.465
1eh4IC1Casein kinase I homolog 12.7.11.10.464
1ke6LS2Cyclin-dependent kinase 22.7.11.220.464
1ol7ADPAurora kinase A2.7.11.10.464
1zeoC01Peroxisome proliferator-activated receptor gamma/0.464
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.464
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.464
2i0ePDSProtein kinase C beta type2.7.11.130.464
2wihP48Cyclin-dependent kinase 22.7.11.220.464
4bcpT3CCyclin-dependent kinase 22.7.11.220.464
4hge15VTyrosine-protein kinase JAK2/0.464
4jnkZHKL-lactate dehydrogenase A chain1.1.1.270.464
4k33ACPFibroblast growth factor receptor 32.7.10.10.464
4qmtH1NSerine/threonine-protein kinase 242.7.11.10.464
2ptfFMNUncharacterized protein MTH_863/0.463
3hmm855TGF-beta receptor type-12.7.11.300.463
4aqc88ATyrosine-protein kinase JAK2/0.463
4fg9ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.463
1aq1STUCyclin-dependent kinase 22.7.11.220.462
1oiyN41Cyclin-dependent kinase 22.7.11.220.462
1pxoCK7Cyclin-dependent kinase 22.7.11.220.462
1rfvADPPyridoxal kinase2.7.1.350.462
2a4lRRCCyclin-dependent kinase 22.7.11.220.462
2qo9ANPEphrin type-A receptor 32.7.10.10.462
3le62BZCyclin-dependent kinase 22.7.11.220.462
3ttjJBIMitogen-activated protein kinase 102.7.11.240.462
3vs7KS1Tyrosine-protein kinase HCK2.7.10.20.462
4grb0XGCasein kinase II subunit alpha2.7.11.10.462
4zirANPEnergy-coupling factor transporter ATP-binding protein EcfA23.6.30.462
4zirANPEnergy-coupling factor transporter ATP-binding protein EcfA1/0.462
2brgDFYSerine/threonine-protein kinase Chk12.7.11.10.461
2x2mX2MProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.461
2ydjYDJSerine/threonine-protein kinase Chk12.7.11.10.461
3c4xATPRhodopsin kinase/0.461
3cy3JN5Serine/threonine-protein kinase pim-12.7.11.10.461
4jq8KJ8Epidermal growth factor receptor2.7.10.10.461
4k1b1OCSerine/threonine-protein kinase pim-12.7.11.10.461
4mq22C4Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.461
4o0rX4ZSerine/threonine-protein kinase PAK 12.7.11.10.461
5auwQUEDeath-associated protein kinase 12.7.11.10.461
1lp4ANPCasein kinase II subunit alpha2.7.11.10.460
2csnCKICasein kinase I homolog 12.7.11.10.460
2j4z626Aurora kinase A2.7.11.10.460
3uixQ17Serine/threonine-protein kinase pim-12.7.11.10.460
4gk2L66Ephrin type-A receptor 32.7.10.10.460
5dpvSKEAurora kinase A2.7.11.10.460
5e8ySTUTGF-beta receptor type-22.7.11.300.460
1stcSTUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.459
2wxvWXVCyclin-dependent kinase 22.7.11.220.459
3a62STURibosomal protein S6 kinase beta-12.7.11.10.459
3vrzVRZTyrosine-protein kinase HCK2.7.10.20.459
4dgnLU2Casein kinase II subunit alpha2.7.11.10.459
4dgo0JWCasein kinase II subunit alpha2.7.11.10.459
4g3e0WCMitogen-activated protein kinase kinase kinase 142.7.11.250.459
4k181OBSerine/threonine-protein kinase pim-12.7.11.10.459
4nm7ADPGlycogen synthase kinase-3 beta2.7.11.260.459
4qo9627Serine/threonine-protein kinase 242.7.11.10.459
4yhjAN2G protein-coupled receptor kinase 42.7.11.160.459
1fvv107Cyclin-dependent kinase 22.7.11.220.458
2c5yMTWCyclin-dependent kinase 22.7.11.220.458
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.458
2r0uM54Serine/threonine-protein kinase Chk12.7.11.10.458
2w7xD1ASerine/threonine-protein kinase Chk22.7.11.10.458
3mtlFEFCyclin-dependent kinase 162.7.11.220.458
3ormAGSSerine/threonine protein kinase/0.458
3zep1NXTyrosine-protein kinase JAK32.7.10.20.458
3zsgT75Mitogen-activated protein kinase 14/0.458
4gfo0X2Non-receptor tyrosine-protein kinase TYK22.7.10.20.458
4i0t1B6Tyrosine-protein kinase SYK2.7.10.20.458
4nk92K5Fibroblast growth factor receptor 1/0.458
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.457
2acxANPG protein-coupled receptor kinase 62.7.11.160.457
2ayp43ASerine/threonine-protein kinase Chk12.7.11.10.457
2j2iLY4Serine/threonine-protein kinase pim-12.7.11.10.457
2o0uC0MMitogen-activated protein kinase 102.7.11.240.457
3mfuANPPeripheral plasma membrane protein CASK2.7.11.10.457
4f081RSTyrosine-protein kinase JAK2/0.457
4oavACP2-5A-dependent ribonuclease3.1.260.457
1okySTU3-phosphoinositide-dependent protein kinase 12.7.11.10.456
2brhDFWSerine/threonine-protein kinase Chk12.7.11.10.456
2iqgF2IBeta-secretase 13.4.23.460.456
2itpAEEEpidermal growth factor receptor2.7.10.10.456
2j0lANPFocal adhesion kinase 12.7.10.20.456
2pvlP55Casein kinase II subunit alpha2.7.11.10.456
2rioADPSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.456
3cylVITBasic phospholipase A2 homolog piratoxin-2/0.456
3kvxFMYMitogen-activated protein kinase 102.7.11.240.456
3pe2E1BCasein kinase II subunit alpha2.7.11.10.456
3sc13S13-phosphoinositide-dependent protein kinase 12.7.11.10.456
3w16P9JAurora kinase A2.7.11.10.456
4eutBX7Serine/threonine-protein kinase TBK12.7.11.10.456
1vjy460TGF-beta receptor type-12.7.11.300.455
1yi4ADNSerine/threonine-protein kinase pim-12.7.11.10.455
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.455
2hy0306Serine/threonine-protein kinase Chk12.7.11.10.455
2o65MYFSerine/threonine-protein kinase pim-12.7.11.10.455
2w17I19Cyclin-dependent kinase 22.7.11.220.455
2x1nX1NCyclin-dependent kinase 22.7.11.220.455
2yn8STUEphrin type-B receptor 42.7.10.10.455
3ma301ISerine/threonine-protein kinase pim-12.7.11.10.455
3qcq3Q03-phosphoinositide-dependent protein kinase 12.7.11.10.455
4aojV4ZHigh affinity nerve growth factor receptor2.7.10.10.455
4c3pACPAurora kinase A2.7.11.10.455
4ckiADNProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.455
4ek816KCyclin-dependent kinase 22.7.11.220.455
4f650S9Fibroblast growth factor receptor 1/0.455
4j99ACPFibroblast growth factor receptor 2/0.455
4r8qADPMitotic checkpoint serine/threonine-protein kinase BUB12.7.11.10.455
1oiuN76Cyclin-dependent kinase 22.7.11.220.454
1u4dDBQActivated CDC42 kinase 1/0.454
1xwsBI1Serine/threonine-protein kinase pim-12.7.11.10.454
2ckeIQUDeath-associated protein kinase 2/0.454
3cd3STUTyrosine-protein kinase Fes/Fps2.7.10.20.454
3ddpRC8Cyclin-dependent kinase 22.7.11.220.454
3gbuATPUncharacterized sugar kinase PH14592.7.10.454
4anwO92Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.454
4aotGW8Serine/threonine-protein kinase 102.7.11.10.454
4b99R4LMitogen-activated protein kinase 72.7.11.240.454
4id71G0Activated CDC42 kinase 1/0.454
4rrvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.454
1q8yADPSerine/threonine-protein kinase SKY12.7.11.10.453
2c6eHPMAurora kinase A2.7.11.10.453
2cgx3D3Serine/threonine-protein kinase Chk12.7.11.10.453
2fumMIXSerine/threonine-protein kinase PknB2.7.11.10.453
2o2u738Mitogen-activated protein kinase 102.7.11.240.453
2vagV25Dual specificity protein kinase CLK12.7.12.10.453
2x6dX6DAurora kinase A2.7.11.10.453
3cblSTUTyrosine-protein kinase Fes/Fps2.7.10.20.453
3icrCOACoenzyme A disulfide reductase/0.453
3lfsA07Cyclin-dependent kinase 22.7.11.220.453
3mdmFJZCholesterol 24-hydroxylase/0.453
3r9dX6BCyclin-dependent kinase 22.7.11.220.453
3r9hZ67Cyclin-dependent kinase 22.7.11.220.453
3vs5VSGTyrosine-protein kinase HCK2.7.10.20.453
4jrvKJVEpidermal growth factor receptor2.7.10.10.453
1m2pHNACasein kinase II subunit alpha2.7.11.10.452
1oguST8Cyclin-dependent kinase 22.7.11.220.452
2uzlC94Cyclin-dependent kinase 22.7.11.220.452
3bkbSTUTyrosine-protein kinase Fes/Fps2.7.10.20.452
3cjgKIMVascular endothelial growth factor receptor 22.7.10.10.452
3nlb5BESerine/threonine-protein kinase Chk12.7.11.10.452
3tnwF18Cyclin-dependent kinase 22.7.11.220.452
4g3jVNTLanosterol 14-alpha-demethylase/0.452
1d4aFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.451
1pmv537Mitogen-activated protein kinase 102.7.11.240.451
1pyePM1Cyclin-dependent kinase 22.7.11.220.451
2br1PFPSerine/threonine-protein kinase Chk12.7.11.10.451
2c6tDT5Cyclin-dependent kinase 22.7.11.220.451
2chlDKICasein kinase I isoform gamma-32.7.11.10.451
2uzbC75Cyclin-dependent kinase 22.7.11.220.451
2xp2VGHALK tyrosine kinase receptor2.7.10.10.451
3bhtMFRCyclin-dependent kinase 22.7.11.220.451
3e5aVX6Aurora kinase A2.7.11.10.451
3s1h56ZCyclin-dependent kinase 22.7.11.220.451
3v4tUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.451
3w18N13Aurora kinase A2.7.11.10.451
4ez50RSCyclin-dependent kinase 62.7.11.220.451
4fl3ANPTyrosine-protein kinase SYK2.7.10.20.451
4fsnA58Serine/threonine-protein kinase Chk12.7.11.10.451
4fv7E94Mitogen-activated protein kinase 12.7.11.240.451
4lmuQUESerine/threonine-protein kinase pim-12.7.11.10.451
4o0uADNAurora kinase A2.7.11.10.451
4riyADPEpidermal growth factor receptor2.7.10.10.451
1gg5FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.450
1xjdSTUProtein kinase C theta type2.7.11.130.450
1y91CT9Cyclin-dependent kinase 22.7.11.220.450
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.450
2izsBRQCasein kinase I isoform gamma-32.7.11.10.450
2w1eL0EAurora kinase A2.7.11.10.450
2xa4AZ5Tyrosine-protein kinase JAK2/0.450
2yirYIRSerine/threonine-protein kinase Chk22.7.11.10.450
3c50ADPRhodopsin kinase/0.450
3own3OWRenin3.4.23.150.450
4e730NRMitogen-activated protein kinase 82.7.11.240.450
4g7gVFVLanosterol 14-alpha-demethylase/0.450
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.450
4iwq1FVSerine/threonine-protein kinase TBK12.7.11.10.450
4mbl26LSerine/threonine-protein kinase pim-12.7.11.10.450
5ar4SB2Receptor-interacting serine/threonine-protein kinase 22.7.11.10.450
1bwsNDPGDP-L-fucose synthase/0.449
1okzUCN3-phosphoinositide-dependent protein kinase 12.7.11.10.449
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.449
2jdvL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.449
2q5g1FAPeroxisome proliferator-activated receptor delta/0.449
3q9xEMOCasein kinase II subunit alpha2.7.11.10.449
3rk507ZCyclin-dependent kinase 22.7.11.220.449
4dpuAGSMevalonate diphosphate decarboxylase/0.449
4qmxH8HSerine/threonine-protein kinase 242.7.11.10.449
4yuqKS1Calmodulin-like domain protein kinase/0.449
1k7l544Peroxisome proliferator-activated receptor alpha/0.448
1p4fDRGDeath-associated protein kinase 12.7.11.10.448
1q12ATPMaltose/maltodextrin import ATP-binding protein MalK/0.448
1u5rATPSerine/threonine-protein kinase TAO22.7.11.10.448
1y0s331Peroxisome proliferator-activated receptor delta/0.448
1yvj4STTyrosine-protein kinase JAK32.7.10.20.448
2bdjHETProto-oncogene tyrosine-protein kinase Src2.7.10.20.448
2bkzSBCCyclin-dependent kinase 22.7.11.220.448
2x8iX8ISerine/threonine-protein kinase Chk12.7.11.10.448
2y6o1N1Ephrin type-A receptor 42.7.10.10.448
2y7jB49Phosphorylase b kinase gamma catalytic chain, liver/testis isoform2.7.11.190.448
2ycqUPXSerine/threonine-protein kinase Chk22.7.11.10.448
3bgpVX1Serine/threonine-protein kinase pim-12.7.11.10.448
3iok1P6Tyrosine-protein kinase JAK2/0.448
3pxkPXKFocal adhesion kinase 12.7.10.20.448
3rk708ZCyclin-dependent kinase 22.7.11.220.448
3v013V0Dual specificity mitogen-activated protein kinase kinase 12.7.12.20.448
4i0r1B4Tyrosine-protein kinase SYK2.7.10.20.448
4kb81QNCasein kinase I isoform delta2.7.11.10.448
4uyaAGSMitogen-activated protein kinase kinase kinase 212.7.11.250.448
5dr6SKEAurora kinase A2.7.11.10.448
1dayGNPCasein kinase II subunit alpha2.7.11.10.447
1dxqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.447
1mp0NADAlcohol dehydrogenase class-31.1.1.10.447
1rw8580TGF-beta receptor type-12.7.11.300.447
1zltHYMSerine/threonine-protein kinase Chk12.7.11.10.447
2f4bEHAPeroxisome proliferator-activated receptor gamma/0.447
2ittAEEEpidermal growth factor receptor2.7.10.10.447
2uzeC95Cyclin-dependent kinase 22.7.11.220.447
2yac937Serine/threonine-protein kinase PLK12.7.11.210.447
3cxw7CPSerine/threonine-protein kinase pim-12.7.11.10.447
3gu6ADPDeath-associated protein kinase 12.7.11.10.447
3hdmMMGSerine/threonine-protein kinase Sgk12.7.11.10.447
3lpjZ75Beta-secretase 13.4.23.460.447
3qa2XNAKetohexokinase/0.447
3ral04ZCyclin-dependent kinase 22.7.11.220.447
3roy22ZCyclin-dependent kinase 22.7.11.220.447
3s2pPMUCyclin-dependent kinase 22.7.11.220.447
3zonIK1Non-receptor tyrosine-protein kinase TYK22.7.10.20.447
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
4bcnT9NCyclin-dependent kinase 22.7.11.220.447
4c3rACPAurora kinase A2.7.11.10.447
4fkw62KCyclin-dependent kinase 22.7.11.220.447
4gih0X5Non-receptor tyrosine-protein kinase TYK22.7.10.20.447
5ackATP3-phosphoinositide-dependent protein kinase 12.7.11.10.447
5e92ANPTGF-beta receptor type-22.7.11.300.447
1kboFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.446
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.446
1siqFADGlutaryl-CoA dehydrogenase, mitochondrial1.3.8.60.446
2bfyH1NAurora kinase B-A2.7.11.10.446
2iw94SPCyclin-dependent kinase 22.7.11.220.446
2jedLG8Protein kinase C theta type2.7.11.130.446
2om9AJAPeroxisome proliferator-activated receptor gamma/0.446
2wmuZYUSerine/threonine-protein kinase Chk12.7.11.10.446
3eljGS7Mitogen-activated protein kinase 82.7.11.240.446
3ezrEZRCyclin-dependent kinase 22.7.11.220.446
3lpkZ76Beta-secretase 13.4.23.460.446
3tubFPUTyrosine-protein kinase SYK2.7.10.20.446
4bznUGXSerine/threonine-protein kinase pim-12.7.11.10.446
4ft5H2KSerine/threonine-protein kinase Chk12.7.11.10.446
4fuyEK2Mitogen-activated protein kinase 12.7.11.240.446
5c03AGSNon-receptor tyrosine-protein kinase TYK22.7.10.20.446
1gih1PUCyclin-dependent kinase 22.7.11.220.445
1h1s4SPCyclin-dependent kinase 22.7.11.220.445
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.445
1v1k3FPCyclin-dependent kinase 22.7.11.220.445
2owb626Serine/threonine-protein kinase PLK12.7.11.210.445
2qo7ANPEphrin type-A receptor 32.7.10.10.445
3at3ATKCasein kinase II subunit alpha2.7.11.10.445
3jpv1DRSerine/threonine-protein kinase pim-12.7.11.10.445
4f640S8Fibroblast growth factor receptor 1/0.445
4k0y1OASerine/threonine-protein kinase pim-12.7.11.10.445
5cshATPCasein kinase II subunit alpha2.7.11.10.445
2a94AP0L-lactate dehydrogenase1.1.1.270.444
2bhhRYUCyclin-dependent kinase 22.7.11.220.444
2pziAXXSerine/threonine-protein kinase PknG2.7.11.10.444
2uzdC85Cyclin-dependent kinase 22.7.11.220.444
2uztSS3cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.444
2wmwZYWSerine/threonine-protein kinase Chk12.7.11.10.444
2yexYEXSerine/threonine-protein kinase Chk12.7.11.10.444
2yitYITSerine/threonine-protein kinase Chk22.7.11.10.444
3ad9NADSubunit alpha of sarocosine oxidase/0.444
3cgoJNOMitogen-activated protein kinase 102.7.11.240.444
3nunJMZ3-phosphoinositide-dependent protein kinase 12.7.11.10.444
3qcs3Q13-phosphoinositide-dependent protein kinase 12.7.11.10.444
3r8pZ46Cyclin-dependent kinase 22.7.11.220.444
3vsoEK1Peroxisome proliferator-activated receptor gamma/0.444
4fnyI3KALK tyrosine kinase receptor2.7.10.10.444
4ftn2HKSerine/threonine-protein kinase Chk12.7.11.10.444
4jr7GNPCasein kinase II subunit alpha2.7.11.10.444
4lopSB4Mitogen-activated protein kinase 14/0.444
4mwhATPCasein kinase II subunit alpha2.7.11.10.444
4n6z2HWSerine/threonine-protein kinase pim-12.7.11.10.444
4xguADPPutative pachytene checkpoint protein 2/0.444
4ykfFADAlkyl hydroperoxide reductase subunit F1.8.10.444
5amnDTQProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.444
5eaiFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.444
1ny3ADPMAP kinase-activated protein kinase 22.7.11.10.443
1om1IQACasein kinase II subunit alpha2.7.11.10.443
2b52D42Cyclin-dependent kinase 22.7.11.220.443
2brnDF1Serine/threonine-protein kinase Chk12.7.11.10.443
2evaADNMitogen-activated protein kinase kinase kinase 72.7.11.250.443
2j0j4STFocal adhesion kinase 12.7.10.20.443
2qhn582Serine/threonine-protein kinase Chk12.7.11.10.443
2wmsZYSSerine/threonine-protein kinase Chk12.7.11.10.443
2xk9XK9Serine/threonine-protein kinase Chk22.7.11.10.443
3a7hATPSerine/threonine-protein kinase 242.7.11.10.443
3iw4LW4Protein kinase C alpha type2.7.11.130.443
3oqkS52Renin3.4.23.150.443
3r9oZ71Cyclin-dependent kinase 22.7.11.220.443
3vid4TTVascular endothelial growth factor receptor 22.7.10.10.443
3vs6VSHTyrosine-protein kinase HCK2.7.10.20.443
3we45FIRibosomal protein S6 kinase beta-12.7.11.10.443
4bdbODOSerine/threonine-protein kinase Chk22.7.11.10.443
4fz70VHTyrosine-protein kinase SYK2.7.10.20.443
4kb81QOCasein kinase I isoform delta2.7.11.10.443
4loqSB4Mitogen-activated protein kinase 14/0.443
4nka2K7Fibroblast growth factor receptor 1/0.443
5dmzADPMitotic checkpoint serine/threonine-protein kinase BUB12.7.11.10.443
1rv1IMZE3 ubiquitin-protein ligase Mdm26.3.20.442
2wtdZZKSerine/threonine-protein kinase Chk22.7.11.10.442
2xrwANPMitogen-activated protein kinase 82.7.11.240.442
3bfb9ODPheromone-binding protein ASP1/0.442
3g49NAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.442
3ggfGVDSerine/threonine-protein kinase 26/0.442
3gw9VNILanosterol 14-alpha-demethylase/0.442
3hx4ANPCalmodulin-domain protein kinase 1/0.442
3m42HGFMAP kinase-activated protein kinase 22.7.11.10.442
3rk909ZCyclin-dependent kinase 22.7.11.220.442
3umxQ18Serine/threonine-protein kinase pim-12.7.11.10.442
4cd0AWJALK tyrosine kinase receptor2.7.10.10.442
4f9mFCMPeroxisome proliferator-activated receptor gamma/0.442
4fsmHK1Serine/threonine-protein kinase Chk12.7.11.10.442
4l9i8PRRhodopsin kinase/0.442
1g5sI17Cyclin-dependent kinase 22.7.11.220.441
1h69FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.441
1pjkANPCasein kinase II subunit alpha2.7.11.10.441
1t2cNAIL-lactate dehydrogenase1.1.1.270.441
2eufLQQCyclin-dependent kinase 62.7.11.220.441
2np8CC3Aurora kinase A2.7.11.10.441
2py3ACPFibroblast growth factor receptor 2/0.441
2q9fC3SCholesterol 24-hydroxylase/0.441
2qocANPEphrin type-A receptor 32.7.10.10.441
2x9fX9FEphrin type-B receptor 42.7.10.10.441
2xbjXBJSerine/threonine-protein kinase Chk22.7.11.10.441
3hrcATP3-phosphoinositide-dependent protein kinase 12.7.11.10.441
3ml8ML8Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
3oqfS51Renin3.4.23.150.441
3vcyUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.441
4bcmT7ZCyclin-dependent kinase 22.7.11.220.441
4oacADPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.441
4zohFADPutative oxidoreductase FAD-binding subunit/0.441
5auvAGIDeath-associated protein kinase 12.7.11.10.441
1dirNADDihydropteridine reductase1.5.1.340.440
1tw2ERTCarminomycin 4-O-methyltransferase DnrK2.1.1.2920.440
1v0pPVBCell division control protein 2 homolog2.7.11.220.440
2bilBI1Serine/threonine-protein kinase pim-12.7.11.10.440
2c6lDT4Cyclin-dependent kinase 22.7.11.220.440
2fgjATPAlpha-hemolysin translocation ATP-binding protein HlyB/0.440
2hw1ANPKetohexokinase/0.440
2wedPP6Penicillopepsin-13.4.23.200.440
2wpa889Cyclin-dependent kinase 22.7.11.220.440
2wyvNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.440
3em6017Gag-Pol polyprotein3.4.23.160.440
3mpjFADGlutaryl-CoA dehydrogenase1.3.99.320.440
3my5RFZCyclin-dependent kinase 22.7.11.220.440
3qu0X40Cyclin-dependent kinase 22.7.11.220.440
3rni21ZCyclin-dependent kinase 22.7.11.220.440
3wi6YRZMAP kinase-activated protein kinase 22.7.11.10.440
3zm422TDual specificity mitogen-activated protein kinase kinase 12.7.12.20.440
3zxtACPDeath-associated protein kinase 12.7.11.10.440
4btjADPTau-tubulin kinase 12.7.11.10.440
4foc0UUALK tyrosine kinase receptor2.7.10.10.440
4jlcSU6Serine/threonine-protein kinase TBK12.7.11.10.440
4oj4DIFPeroxisome proliferator-activated receptor gamma/0.440
4wboANWRhodopsin kinase/0.440