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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3evjNTOAntithrombin-III

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
3evjNTOAntithrombin-III/1.000
2jb4A14Isopenicillin N synthase1.21.3.10.535
1hb1OCVIsopenicillin N synthase1.21.3.10.526
1hb3SCVIsopenicillin N synthase1.21.3.10.512
1qiqACCIsopenicillin N synthase1.21.3.10.509
2wo7ASVIsopenicillin N synthase1.21.3.10.505
4apuA2KProgesterone receptor/0.499
4if5ACOAlpha-tubulin N-acetyltransferase 1/0.498
2y60M8FIsopenicillin N synthase1.21.3.10.496
1xddAAYIntegrin alpha-L/0.494
2bjsACVIsopenicillin N synthase1.21.3.10.494
2bu9HFVIsopenicillin N synthase1.21.3.10.494
2x9dITCTetracycline repressor protein class D/0.490
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.489
3f3sNADLambda-crystallin homolog/0.488
4xbjIN5Alanine racemase, biosynthetic/0.487
2iviACWIsopenicillin N synthase1.21.3.10.485
1eyyNAPNADP-dependent fatty aldehyde dehydrogenase1.2.1.40.483
1oc1ASVIsopenicillin N synthase1.21.3.10.483
2v4lABJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.483
2yq92AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.483
1qjfACSIsopenicillin N synthase1.21.3.10.482
5kf8ACOPredicted acetyltransferase/0.482
2dr3ADPUPF0273 protein PH0284/0.481
2v7qADPATP synthase subunit beta, mitochondrial3.6.3.140.481
3zoiM2WIsopenicillin N synthase1.21.3.10.481
5kghACOPredicted acetyltransferase/0.481
1eiiRTLRetinol-binding protein 2/0.480
2fr3REACellular retinoic acid-binding protein 2/0.480
2p2bPRXAcetyl-coenzyme A synthetase/0.480
3anmSYD1-deoxy-D-xylulose 5-phosphate reductoisomerase1.1.1.2670.480
3ekuCY9Actin-5C/0.480
2vosADPFolylpolyglutamate synthase/0.479
4cukNAID-lactate dehydrogenase/0.479
5efwFMNNPH1-1/0.479
1juvNDPDihydrofolate reductase1.5.1.30.478
1w06W05Isopenicillin N synthase1.21.3.10.478
2d29FADAcyl-CoA dehydrogenase/0.478
4wdfA2P2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.478
1cqp803Integrin alpha-L/0.477
2q61SF1Peroxisome proliferator-activated receptor gamma/0.477
2vbpVB1Isopenicillin N synthase1.21.3.10.477
4uyf73BBromodomain-containing protein 2/0.477
1uzwCDHIsopenicillin N synthase1.21.3.10.476
2pnuENMAndrogen receptor/0.476
3c3xNAPEugenol synthase 11.1.1.3180.476
3mjrAC2Deoxycytidine kinase2.7.1.740.476
4y9xUPGGlucosyl-3-phosphoglycerate synthase2.4.1.2660.476
2cbrA80Cellular retinoic acid-binding protein 1/0.475
3u2lFADFAD-linked sulfhydryl oxidase ALR1.8.3.20.475
4psbGA3Cytokinin-specific binding protein/0.474
4eqxFADCoenzyme A disulfide reductase/0.473
4wda2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.473
1bk0ACVIsopenicillin N synthase1.21.3.10.472
1g05BBHStromelysin-13.4.24.170.472
1stdBFSScytalone dehydratase4.2.1.940.472
3u2mFADFAD-linked sulfhydryl oxidase ALR1.8.3.20.472
4gs4ACOAlpha-tubulin N-acetyltransferase 1/0.472
2y6fM9FIsopenicillin N synthase1.21.3.10.471
2yp0OVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.471
3q33ACOHistone acetyltransferase RTT1092.3.1.480.471
3vri1KXHLA class I histocompatibility antigen, B-57 alpha chain/0.471
4h8004TAldehyde dehydrogenase, dimeric NADP-preferring/0.471
2yig5ELCollagenase 33.4.240.470
4fvrATPTyrosine-protein kinase JAK2/0.470
4oztP1AEcdysone receptor, putative/0.470
1bcpATPPertussis toxin subunit 4/0.469
1bcpATPPertussis toxin subunit 5/0.469
3g4gD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.469
4a2aATPCell division protein FtsA/0.469
1mvsDTMDihydrofolate reductase1.5.1.30.468
3d5qT30Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.468
3zbzOVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.468
3ziaADPATP synthase subunit beta, mitochondrial3.6.3.140.468
1swtBTNStreptavidin/0.467
2hunNAD336aa long hypothetical dTDP-glucose 4,6-dehydratase/0.467
3bgxMEFThymidylate synthase/0.467
4e0hFADMitochondrial FAD-linked sulfhydryl oxidase ERV11.8.3.20.467
1mznBM6Retinoic acid receptor RXR-alpha/0.466
1sojIBMcGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.466
1toiHCIAspartate aminotransferase2.6.1.10.466
2bxoOPBSerum albumin/0.466
2c2aADPSensor histidine kinase/0.466
2jc6QPPCalcium/calmodulin-dependent protein kinase type 1D2.7.11.170.466
2ow9SP6Collagenase 33.4.240.466
2po7CHDFerrochelatase, mitochondrial4.99.1.10.466
3gobHXXDdmC/0.466
3wi2P98cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.466
3zkyWT4Isopenicillin N synthase1.21.3.10.466
5kf1ACOPredicted acetyltransferase/0.466
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.465
1r6g442Thyroid hormone receptor beta/0.465
2c3qGTXGlutathione S-transferase theta-12.5.1.180.465
2jlcTPP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.465
3i0pNADMalate dehydrogenase, putative/0.465
3qvwNADMyo-inositol-1-phosphate synthase (Ino1)/0.465
3wv9FEGHmd co-occurring protein HcgE/0.465
4ku5DCC3-oxoacyl-[ACP] synthase III/0.465
4nd3NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.465
2q1sNAIPutative nucleotide sugar epimerase/ dehydratase/0.464
3f7bAG5Carbonic anhydrase 44.2.1.10.464
3hu1AGSTransitional endoplasmic reticulum ATPase3.6.4.60.464
4kwhNAPReductase homolog/0.464
5f2rACP78 kDa glucose-regulated protein/0.464
1g28FMNPHY3/0.463
1hovI5272 kDa type IV collagenase3.4.24.240.463
1obnASVIsopenicillin N synthase1.21.3.10.463
2jizANPATP synthase subunit beta, mitochondrial3.6.3.140.463
3qwbNDPProbable quinone oxidoreductase1.6.5.50.463
4avlTMPPolymerase acidic protein/0.463
4ja1NGHStromelysin-13.4.24.170.463
4jldADPAdenylate kinase/0.463
1mvcBM6Retinoic acid receptor RXR-alpha/0.462
1pagFMPAntiviral protein I3.2.2.220.462
4em3FADCoenzyme A disulfide reductase/0.462
5dp2NAPCurF/0.462
1b2lNDCAlcohol dehydrogenase1.1.1.10.461
1lc3NADBiliverdin reductase A1.3.1.240.461
1s7gNADNAD-dependent protein deacylase 2/0.461
1uyfPU1Heat shock protein HSP 90-alpha/0.461
2xvv9DNSerum albumin/0.461
2z6iFMN2-nitropropane dioxygenase/0.461
3da1FADGlycerol-3-phosphate dehydrogenase/0.461
3gwfFADCyclohexanone monooxygenase/0.461
3zbsOVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.461
4r21STRCytochrome P450 family 17 polypeptide 2/0.461
1bwlFMNNADPH dehydrogenase 11.6.99.10.460
1fm69CRRetinoic acid receptor RXR-alpha/0.460
1qorNDPQuinone oxidoreductase 1/0.460
1rdtL79Retinoic acid receptor RXR-alpha/0.460
2j14GNIPeroxisome proliferator-activated receptor delta/0.460
3v2uATPProtein GAL3/0.460
3zbrNAP2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.460
4ht2V50Carbonic anhydrase 124.2.1.10.460
4jv81M1Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.460
5djuFMNNPH1-2/0.460
5kf9ACOPredicted acetyltransferase/0.460
1blzACVIsopenicillin N synthase1.21.3.10.459
1g7vPAI2-dehydro-3-deoxyphosphooctonate aldolase2.5.1.550.459
1pg3PRXAcetyl-coenzyme A synthetase/0.459
1reqDCAMethylmalonyl-CoA mutase large subunit5.4.99.20.459
3g8eIS1Nicotinamide phosphoribosyltransferase2.4.2.120.459
3i59N6RCRP-like cAMP-activated global transcriptional regulator/0.459
4hy6FJ1Heat shock protein HSP 90-alpha/0.459
4isk1JYThymidylate synthase/0.459
4q0kGA3Phytohormone-binding protein/0.459
4xcvNDPProbable hydroxyacid dehydrogenase protein/0.459
4y9lFADAcyl-CoA dehydrogenase family member 11/0.459
5stdUNNScytalone dehydratase4.2.1.940.459
1q0rAKTAclacinomycin methylesterase RdmC3.1.1.950.458
1txtCAAHMG-CoA synthase/0.458
2ejzSAHDiphthine synthase/0.458
2vcmM11Isopenicillin N synthase1.21.3.10.458
2woa023Macrophage metalloelastase3.4.24.650.458
2x7hPFNProstaglandin reductase 310.458
3bqdDAYGlucocorticoid receptor/0.458
3mnrSD1Heat shock protein HSP 90-alpha/0.458
4cerVL4Integrase/0.458
4fqsLYAThymidylate synthase ThyA/0.458
4jl6ADPAdenylate kinase/0.458
3sn6P0GBeta-2 adrenergic receptor/0.458
1fduESTEstradiol 17-beta-dehydrogenase 11.1.1.620.457
2vo7M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.457
3sf6FDAGlutaryl-CoA dehydrogenase/0.457
4qjqOTRLactoperoxidase/0.457
4rpgFADUDP-galactopyranose mutase5.4.99.90.457
5hbrCOAAcyl-CoA synthetase (NDP forming)/0.457
1cbqRE9Cellular retinoic acid-binding protein 2/0.456
1fdwESTEstradiol 17-beta-dehydrogenase 11.1.1.620.456
1thnADPAnti-sigma F factor/0.456
2c27ACOMycothiol acetyltransferase2.3.1.1890.456
2j9lATPH(+)/Cl(-) exchange transporter 5/0.456
2wpwACOOrf14/0.456
2xzwATPNitrogen regulatory protein P-II/0.456
2ym2NAPPhenylacetone monooxygenase1.14.13.920.456
3cs8BRLPeroxisome proliferator-activated receptor gamma/0.456
3ghwGHWDihydrofolate reductase1.5.1.30.456
3iocA5DPantothenate synthetase6.3.2.10.456
3issEPUUDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.456
4ag5ADPType IV secretory pathway VirB4 components-like protein/0.456
4bb3KKAIsopenicillin N synthase1.21.3.10.456
4ced9NSIntegrase/0.456
4jzr4JREgl nine homolog 1/0.456
4k6i9RARetinoic acid receptor RXR-alpha/0.456
1cjwCOTSerotonin N-acetyltransferase/0.455
1d8fSPIStromelysin-13.4.24.170.455
1drbMTXDihydrofolate reductase1.5.1.30.455
2fw3BUICarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.455
2p1t3TNRetinoic acid receptor RXR-alpha/0.455
2p9cNAID-3-phosphoglycerate dehydrogenase1.1.1.950.455
2pdaTPPPyruvate synthase/0.455
2vigFADShort-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.10.455
2ydd2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.455
3b1jNADGlyceraldehyde-3-phosphate dehydrogenase/0.455
3e2sFADBifunctional protein PutA1.5.5.20.455
3kvxFMYMitogen-activated protein kinase 102.7.11.240.455
3oiaA31Camphor 5-monooxygenase1.14.15.10.455
3qeoLLTDeoxycytidine kinase2.7.1.740.455
3s1dZIRCytokinin dehydrogenase 11.5.99.120.455
4ldkFADFAD-linked sulfhydryl oxidase ALR1.8.3.20.455
1uttCP8Macrophage metalloelastase3.4.24.650.454
1yw7A41Methionine aminopeptidase 2/0.454
2ic3HBYGag-Pol polyprotein2.7.7.490.454
2jl1NAPTriphenylmethane reductase/0.454
3dv3MEKDual specificity mitogen-activated protein kinase kinase 12.7.12.20.454
3f7uAG4Carbonic anhydrase 44.2.1.10.454
3l9lL9LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.454
3tk0FADFAD-linked sulfhydryl oxidase ALR1.8.3.20.454
4bftZVTPantothenate kinase2.7.1.330.454
4bvaT3Ketimine reductase mu-crystallin1.5.1.250.454
4imgNGFN-acetylneuraminate lyase/0.454
4rrmA3TProbable threonine--tRNA ligase 26.1.1.30.454
5agyGTBTau class glutathione S-transferase/0.454
1b4pGPSGlutathione S-transferase Mu 2/0.453
1efpFADElectron transfer flavoprotein subunit alpha/0.453
1f4fTP3Thymidylate synthase/0.453
1kt3RTLRetinol-binding protein 4/0.453
1tysDHFThymidylate synthase/0.453
2dhfDZFDihydrofolate reductase1.5.1.30.453
2zevB71Geranylgeranyl pyrophosphate synthase/0.453
3fu9KIBLaccase-11.10.3.20.453
3znpFADD-amino-acid oxidase1.4.3.30.453
4a84DXCMajor pollen allergen Bet v 1-A/0.453
4co4ATPNitrogen regulatory protein P-II 1/0.453
4l98LRGPeroxisome proliferator-activated receptor gamma/0.453
4n1gCEIObelin/0.453
4ok1198Androgen receptor/0.453
1c7oPPGHemolysin/0.452
1q0zAKAAclacinomycin methylesterase RdmC3.1.1.950.452
1xiuREARetinoic acid receptor RXR/0.452
1yqzCOACoenzyme A disulfide reductase/0.452
2iodMYCDihydroflavonol 4-reductase1.1.1.2190.452
2yphQQY2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.452
3a60STURibosomal protein S6 kinase beta-12.7.11.10.452
3cz7ACOHistone acetyltransferase RTT1092.3.1.480.452
3t195MAGag-Pol polyprotein2.7.7.490.452
4a83DXCMajor pollen allergen Bet v 1-A/0.452
4d7mTDCTetracycline repressor protein class D/0.452
4dbs0HVAldo-keto reductase family 1 member C3/0.452
4do30LAFatty-acid amide hydrolase 13.5.1.990.452
4ge40KEKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.452
4k6fNAPPutative Acetoacetyl-CoA reductase/0.452
5dozNDPJamJ/0.452
1adfTADAlcohol dehydrogenase E chain1.1.1.10.451
1e79ADPATP synthase subunit alpha, mitochondrial/0.451
1e79ADPATP synthase subunit beta, mitochondrial3.6.3.140.451
1mj3HXCEnoyl-CoA hydratase, mitochondrial4.2.1.170.451
2g2hP16Tyrosine-protein kinase ABL12.7.10.20.451
2g78REACellular retinoic acid-binding protein 2/0.451
2rl1UD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.451
3r6sCMPCRP-like cAMP-activated global transcriptional regulator/0.451
4ceqQCHIntegrase/0.451
4du82P0Mevalonate diphosphate decarboxylase/0.451
4eiyZMAAdenosine receptor A2a/0.451
4gllNADUDP-glucuronic acid decarboxylase 14.1.1.350.451
4ips1G4Mycocyclosin synthase1.14.21.90.451
4tmcFMNOld yellow enzyme/0.451
4ure1PSCyclohexanol dehydrogenase/0.451
4xumIMNPeroxisome proliferator-activated receptor gamma/0.451
5i4nATPTyrosine-protein kinase JAK2/0.451
1a72PADAlcohol dehydrogenase E chain1.1.1.10.450
1ib0FADNADH-cytochrome b5 reductase 31.6.2.20.450
1p0hACOMycothiol acetyltransferase2.3.1.1890.450
2ag1TPPBenzaldehyde lyase/0.450
2ddoATPPyridoxine/pyridoxal/pyridoxamine kinase/0.450
2vcwZZAHematopoietic prostaglandin D synthase/0.450
2wpxACOOrf14/0.450
3ad9NADSubunit alpha of sarocosine oxidase/0.450
3hpqAP5Adenylate kinase/0.450
3o73O73Ribosyldihydronicotinamide dehydrogenase [quinone]/0.450
3oafOAGDihydrofolate reductase1.5.1.30.450
3pxyJWSCyclin-dependent kinase 22.7.11.220.450
3ruhNADUDP-N-acetylglucosamine 4-epimerase/0.450
3uovFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.450
3wecAUICytochrome P450/0.450
4a4vYFDPeroxisome proliferator-activated receptor gamma/0.450
4i2q1BTGag-Pol polyprotein2.7.7.490.450
4j531J4Serine/threonine-protein kinase PLK12.7.11.210.450
4p6xHCYGlucocorticoid receptor/0.450
4u9yCOAAlpha-tubulin N-acetyltransferase 1/0.450
1a9zUPGUDP-glucose 4-epimerase5.1.3.20.449
1q6nP90Tyrosine-protein phosphatase non-receptor type 13.1.3.480.449
2uxoTACHTH-type transcriptional regulator TtgR/0.449
3aw9NADNAD-dependent epimerase/dehydratase/0.449
3d45GDPPoly(A)-specific ribonuclease PARN3.1.13.40.449
3g51ANPRibosomal protein S6 kinase alpha-32.7.11.10.449
3jynNDPQuinone oxidoreductase/0.449
4em9TCEPeroxisome proliferator-activated receptor gamma/0.449
4nieNBHNuclear receptor ROR-gamma/0.449
5es7FONLinear gramicidin synthase subunit A/0.449
5fm7ADPRuvB-like helicase/0.449
2am22LGUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase/0.448
2fhnBNIAvidin-related protein 4/5/0.448
2p2qPRXAcetyl-coenzyme A synthetase/0.448
2zbaZBATrichothecene 3-O-acetyltransferase/0.448
2ztsADPUncharacterized protein/0.448
3vqvANPPyrrolysine--tRNA ligase/0.448
3zhsTD6Multifunctional 2-oxoglutarate metabolism enzyme1.2.4.20.448
4da7AC2Purine nucleoside phosphorylase DeoD-type2.4.2.10.448
4ih71ERGenome polyprotein2.7.7.480.448
4j361HRKynurenine 3-monooxygenase/0.448
4o8jADNRNA 3'-terminal phosphate cyclase6.5.1.40.448
4rvuNDPProbable quinone reductase Qor (NADPH:quinone reductase) (Zeta-crystallin homolog protein)/0.448
5b1yNDP3-oxoacyl-[acyl-carrier-protein] reductase/0.448
5ftcADPTPR domain protein/0.448
5irnADPNucleotide binding oligomerization domain containing 2/0.448
1bdbNADCis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase/0.447
1uycPU7Heat shock protein HSP 90-alpha/0.447
1uyePU9Heat shock protein HSP 90-alpha/0.447
1uymPU3Heat shock protein HSP 90-beta/0.447
2egvSAMRibosomal RNA small subunit methyltransferase E2.1.1.1930.447
2ou2ACOHistone acetyltransferase KAT5/0.447
2vbdV10Isopenicillin N synthase1.21.3.10.447
3ddw055Glycogen phosphorylase, liver form2.4.1.10.447
3hmvHBTcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.447
3o4rNAPDehydrogenase/reductase SDR family member 41.1.1.1840.447
3q9zTXQCasein kinase II subunit alpha2.7.11.10.447
4b4w9L9Bifunctional protein FolD/0.447
4b7sQLECytochrome P450 monooxygenase PikC/0.447
4bfwZVWPantothenate kinase2.7.1.330.447
4gxs0YSGlutamate receptor 2/0.447
4jl5ADPAdenylate kinase/0.447
4nt3ZAWLactoperoxidase1.11.1.70.447
4s34ANPMitogen-activated protein kinase 12.7.11.240.447
5djtFMNNPH1-2/0.447
1dcyI3NPhospholipase A2, membrane associated/0.446
1fnnADPORC1-type DNA replication protein/0.446
1mvtDTMDihydrofolate reductase1.5.1.30.446
1s3uTQDDihydrofolate reductase1.5.1.30.446
2dwpACP6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 32.7.1.1050.446
2p9gNAID-3-phosphoglycerate dehydrogenase1.1.1.950.446
2y8lADP5'-AMP-activated protein kinase subunit gamma-1/0.446
2yozOVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.446
3cgdCOACoenzyme A disulfide reductase/0.446
3f1kNAPUncharacterized oxidoreductase YciK10.446
3f883HTGlycogen synthase kinase-3 beta2.7.11.260.446
3gytDL4Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.446
3hu3AGSTransitional endoplasmic reticulum ATPase3.6.4.60.446
3ivcFG4Pantothenate synthetase6.3.2.10.446
3p8iFMNPentaerythritol tetranitrate reductase/0.446
3zvmADPBifunctional polynucleotide phosphatase/kinase2.7.1.780.446
4gevCB3Thymidylate synthase/0.446
4lva20MNicotinamide phosphoribosyltransferase2.4.2.120.446
4nr42LKCREB-binding protein/0.446
4nyw2O3CREB-binding protein/0.446
1cjvFOKAdenylate cyclase type 2/0.445
1cjvFOKAdenylate cyclase type 5/0.445
1dorFMNDihydroorotate dehydrogenase A (fumarate)1.3.98.10.445
1rq1FADEndoplasmic oxidoreductin-11.8.40.445
1wuaAP8Actin, alpha skeletal muscle/0.445
1zq9SAMProbable dimethyladenosine transferase/0.445
2dcnADP2-keto-3-deoxy-gluconate kinase/0.445
2ic5GNPRas-related C3 botulinum toxin substrate 3/0.445
2rcyNAPPyrroline-5-carboxylate reductase/0.445
2vdyHCYCorticosteroid-binding globulin/0.445
3c0g3AMPeripheral plasma membrane protein CASK2.7.11.10.445
3d2mCOAAmino-acid acetyltransferase/0.445
3havATPAminoglycoside phosphotransferase/0.445
3l9mL9McAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.445
3nxxNDPDihydrofolate reductase1.5.1.30.445
3o2x3O2Collagenase 33.4.240.445
3uceNDPDehydrogenase/0.445
3upkUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.445
4anuEM7Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
4dpeNGHStromelysin-13.4.24.170.445
4fa30SLAldo-keto reductase family 1 member C3/0.445
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.445
4h0yLARActin, alpha skeletal muscle/0.445
4i8vBHFCytochrome P450 1A11.14.14.10.445
4ltsLTSNicotinamide phosphoribosyltransferase2.4.2.120.445
4mxeACON-acetyltransferase ESCO12.3.10.445
4z87GDPInosine-5'-monophosphate dehydrogenase/0.445
5c3aURMHisto-blood group ABO system transferase/0.445
1fm99CRRetinoic acid receptor RXR-alpha/0.444
1j4jACOAcetyltransferase2.3.10.444
1nm6L86Prothrombin3.4.21.50.444
1nquRDL6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.444
1pzhNADLactate dehydrogenase/0.444
1rneC60Renin3.4.23.150.444
2abjCBCBranched-chain-amino-acid aminotransferase, cytosolic2.6.1.420.444
2gj3FADNitrogen fixation regulatory protein2.7.13.30.444
2h29DNDProbable nicotinate-nucleotide adenylyltransferase/0.444
2oo7AP5Adenylate kinase/0.444
2ourCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.444
2qirCOAAminoglycoside 6-N-acetyltransferase type Ib11/0.444
3bxxQUEDihydroflavonol 4-reductase1.1.1.2190.444
3hu2AGSTransitional endoplasmic reticulum ATPase3.6.4.60.444
3l9nL9NcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.444
3nhjA2ZRibosyldihydronicotinamide dehydrogenase [quinone]/0.444
3v0o4GWHisto-blood group ABO system transferase/0.444
4c7kNAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.444
4egnTWOCytochrome P450/0.444
4lrlTTPHD domain protein/0.444
4xd2NAIAlcohol dehydrogenase E chain1.1.1.10.444
4yt5H4MH(2)-forming methylenetetrahydromethanopterin dehydrogenase-related protein MJ1338/0.444
5ej7TD62-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.444
1a8rGTPGTP cyclohydrolase 13.5.4.160.443
1gj5130Prothrombin3.4.21.50.443
1ngjANPHeat shock cognate 71 kDa protein/0.443
1tllFADNitric oxide synthase, brain1.14.13.390.443
1udaUFGUDP-glucose 4-epimerase5.1.3.20.443
2bt4CA23-dehydroquinate dehydratase4.2.1.100.443
2fxuBIDActin, alpha skeletal muscle/0.443
2j4z626Aurora kinase A2.7.11.10.443
2owvSAHDiphthine synthase/0.443
2vd0D27Hematopoietic prostaglandin D synthase/0.443
2wo8077Macrophage metalloelastase3.4.24.650.443
2xi4AFTAcetylcholinesterase3.1.1.70.443
3bgxTMPThymidylate synthase/0.443
3cgbCOACoenzyme A disulfide reductase/0.443
3cpsNADGlyceraldehyde-3-phosphate dehydrogenase/0.443
3dxmN24Actin-related protein 3/0.443
3k3ePDBHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.443
3oev3OEProteasome subunit beta type-53.4.25.10.443
3oev3OEProteasome subunit beta type-63.4.25.10.443
3up4NAP2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.443
3vi7CBDHematopoietic prostaglandin D synthase/0.443
4a2bAGSCell division protein FtsA/0.443
4a31MYAGlycylpeptide N-tetradecanoyltransferase/0.443
4cfbOM3Integrase/0.443
4ckrDI1Epithelial discoidin domain-containing receptor 12.7.10.10.443
4kko1REGag-Pol polyprotein2.7.7.490.443
4nu0AP5Adenylate kinase/0.443
4q72FADBifunctional protein PutA/0.443
4r20AERCytochrome P450 family 17 polypeptide 2/0.443
5cb3APRO-acetyl-ADP-ribose deacetylase/0.443
5hgcHCYUncharacterized protein/0.443
5kf2ACOPredicted acetyltransferase/0.443
7catNDPCatalase1.11.1.60.443
1aquESTEstrogen sulfotransferase, testis isoform2.8.2.40.442
1lf2R37Plasmepsin-23.4.23.390.442
1pl2ABYGlutathione S-transferase A12.5.1.180.442
1qyxASDEstradiol 17-beta-dehydrogenase 11.1.1.620.442
1szgFNSCytochrome b2, mitochondrial1.1.2.30.442
1towCRZFatty acid-binding protein, adipocyte/0.442
1uhlMEIRetinoic acid receptor RXR-beta/0.442
1wsvTHHAminomethyltransferase, mitochondrial/0.442
1wwkNAD307aa long hypothetical phosphoglycerate dehydrogenase/0.442
1xkqNDPUncharacterized protein/0.442
1y4lSVRBasic phospholipase A2 homolog 2/0.442
2admSAMModification methylase TaqI2.1.1.720.442
2bpoFADNADPH--cytochrome P450 reductase/0.442
2hfuMEVMevalonate kinase/0.442
2ivpATPtRNA N6-adenosine threonylcarbamoyltransferase/0.442
2v1aFMNNPH1-1/0.442
2yac937Serine/threonine-protein kinase PLK12.7.11.210.442
3bsc2PDGenome polyprotein2.7.7.480.442
3d2pCOAAmino-acid acetyltransferase/0.442
3isjA8DPantothenate synthetase6.3.2.10.442
3jv7NADSecondary alcohol dehydrogenase/0.442
3jziJZLBiotin carboxylase6.3.4.140.442
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.442
3pd4A3GThreonine--tRNA ligase6.1.1.30.442
3qbtGNPRas-related protein Rab-8A/0.442
3slkNDPPolyketide synthase extender module 2/0.442
3sufSUEPolyprotein/0.442
3ukuC69Actin-related protein 3/0.442
3vwdACOAlpha-tubulin N-acetyltransferase 1/0.442
4a81DXCMajor pollen allergen Bet v 1-A/0.442
4jpc1M6Beta-secretase 13.4.23.460.442
4trj665Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.442
1dvrATFAdenylate kinase/0.441
1ewyFADFerredoxin--NADP reductase1.18.1.20.441
1fx9MJIPhospholipase A2, major isoenzyme3.1.1.40.441
1n83CLRNuclear receptor ROR-alpha/0.441
1necFMNOxygen-insensitive NAD(P)H nitroreductase10.441
1pr1FMBPurine nucleoside phosphorylase DeoD-type/0.441
1siqFADGlutaryl-CoA dehydrogenase, mitochondrial1.3.8.60.441
1uyiPUZHeat shock protein HSP 90-alpha/0.441
1vrwNAIEnoyl-ACP reductase/0.441
1yhjR6CPyridoxal kinase2.7.1.350.441
1ykdCMPAdenylate cyclase/0.441
2eklNADD-3-phosphoglycerate dehydrogenase/0.441
2hveADPNucleoside diphosphate kinase A2.7.4.60.441
2ozrGG1Collagenase 33.4.240.441
2rlcCHDCholoylglycine hydrolase3.5.1.240.441
2yj5ATPCopper-transporting ATPase/0.441
2ykeYKEHeat shock protein HSP 90-alpha/0.441
2yncYNCGlycylpeptide N-tetradecanoyltransferase/0.441
3nhfVVVRibosyldihydronicotinamide dehydrogenase [quinone]/0.441
3oom507Activin receptor type-12.7.11.300.441
3qppPFWcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.441
3r4b74TGag-Pol polyprotein/0.441
4bcqTJFCyclin-dependent kinase 22.7.11.220.441
4gl4NAIAlcohol dehydrogenase class-3/0.441
4lvb20NNicotinamide phosphoribosyltransferase2.4.2.120.441
4ogkTHMUridine phosphorylase2.4.2.30.441
4r7uUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.441
4x28FDAAcyl-CoA dehydrogenase FadE26/0.441
4x28FDAAcyl-CoA dehydrogenase FadE27/0.441
4ys0ADPProtein translocase subunit SecA/0.441
5iu86DZAdenosine receptor A2a/0.441
1jtvTESEstradiol 17-beta-dehydrogenase 11.1.1.620.440
1olmVTQSEC14-like protein 2/0.440
1orkATCTetracycline repressor protein class D/0.440
1rb3MTXDihydrofolate reductase1.5.1.30.440
1swdBTNStreptavidin/0.440
1zthADPRIO-type serine/threonine-protein kinase Rio12.7.11.10.440
2fgjATPAlpha-hemolysin translocation ATP-binding protein HlyB/0.440
2hm9TRRDihydrofolate reductase1.5.1.30.440
2y8qADP5'-AMP-activated protein kinase subunit gamma-1/0.440
2z2dHSIMacrophage metalloelastase3.4.24.650.440
2z7hGG3Geranylgeranyl pyrophosphate synthase/0.440
3a28NADL-2,3-butanediol dehydrogenase1.1.1.760.440
3hy7097A disintegrin and metalloproteinase with thrombospondin motifs 53.4.240.440
3kp4MIITranscriptional regulator TcaR/0.440
3m1vCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.440
3m1vCOMMethyl-coenzyme M reductase I subunit beta2.8.4.10.440
3qe2FMNNADPH--cytochrome P450 reductase/0.440
3ru9NADUDP-N-acetylglucosamine 4-epimerase/0.440
3ue6FMNAureochrome1/0.440
3uleC69Actin-related protein 3/0.440
3up3XCAaceDAF-12/0.440
3w78CBDFMN-dependent NADH-azoreductase/0.440
3zqtTESAndrogen receptor/0.440
4alxIZNAcetylcholine-binding protein/0.440
4cj3E4FIntegrase/0.440
4g48PZBMycocyclosin synthase1.14.21.90.440
4hj6FMNLOV protein/0.440
4loh1SYStimulator of interferon genes protein/0.440
4lsaBLDProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.440
4oviN01Phenylacetone monooxygenase1.14.13.920.440
4ttjFMCPurine nucleoside phosphorylase DeoD-type/0.440
4xmxBESAminopeptidase N3.4.11.20.440
4xz3COAAcyl-CoA synthetase (NDP forming)/0.440
4ytnFADSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial/0.440
5kj1NAJAlcohol dehydrogenase E chain1.1.1.10.440
5uviZMAAdenosine receptor A2a/0.440
5k2bZMAAdenosine receptor A2a/0.440