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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3bptQUE3-hydroxyisobutyryl-CoA hydrolase, mitochondrial3.1.2.4

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
3bptQUE3-hydroxyisobutyryl-CoA hydrolase, mitochondrial3.1.2.41.000
1mj3HXCEnoyl-CoA hydratase, mitochondrial4.2.1.170.517
3ddqRRCCyclin-dependent kinase 22.7.11.220.497
4aotGW8Serine/threonine-protein kinase 102.7.11.10.491
3zh8C58Protein kinase C iota type2.7.11.130.489
3pe2E1BCasein kinase II subunit alpha2.7.11.10.488
3cd3STUTyrosine-protein kinase Fes/Fps2.7.10.20.487
3q0gBCOProbable enoyl-CoA hydratase echA84.2.1.170.486
4fv7E94Mitogen-activated protein kinase 12.7.11.240.484
5cshATPCasein kinase II subunit alpha2.7.11.10.482
2po7CHDFerrochelatase, mitochondrial4.99.1.10.478
3qqkX02Cyclin-dependent kinase 22.7.11.220.478
1q3dSTUGlycogen synthase kinase-3 beta2.7.11.260.477
4anwO92Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.477
2a0cCK9Cyclin-dependent kinase 22.7.11.220.476
2q6bHR23-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.340.475
3cgfJNFMitogen-activated protein kinase 102.7.11.240.475
3u9eCOALmo1369 protein/0.475
1zrzBI1Protein kinase C iota type2.7.11.130.474
2vv9IM9Cyclin-dependent kinase 22.7.11.220.474
2q5g1FAPeroxisome proliferator-activated receptor delta/0.473
3w2rW2REpidermal growth factor receptor2.7.10.10.473
1eh4IC1Casein kinase I homolog 12.7.11.10.472
2znnS44Peroxisome proliferator-activated receptor alpha/0.472
3kljFADNADH-rubredoxin oxidoreductase1.18.1.10.472
3sp6IL2Peroxisome proliferator-activated receptor alpha/0.472
2aqkNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.471
3cgoJNOMitogen-activated protein kinase 102.7.11.240.471
4bqpVMYEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.471
1zeoC01Peroxisome proliferator-activated receptor gamma/0.470
3gggNADPrephenate dehydrogenase/0.470
3v9v21LPeroxisome proliferator-activated receptor gamma/0.470
4a9mP9MBromodomain-containing protein 2/0.470
1q3wATUGlycogen synthase kinase-3 beta2.7.11.260.469
1v1k3FPCyclin-dependent kinase 22.7.11.220.469
3el01UNGag-Pol polyprotein3.4.23.160.469
3i0rRT3Gag-Pol polyprotein2.7.7.490.468
4mq12C3Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.468
1cqp803Integrin alpha-L/0.467
2duv371Cyclin-dependent kinase 22.7.11.220.467
2f4bEHAPeroxisome proliferator-activated receptor gamma/0.467
2w06FRVCyclin-dependent kinase 22.7.11.220.467
2znpK55Peroxisome proliferator-activated receptor delta/0.467
3vjhJ35Peroxisome proliferator-activated receptor gamma/0.467
4xldBRLPeroxisome proliferator-activated receptor gamma/0.467
1jxzBCA4-chlorobenzoyl coenzyme A dehalogenase3.8.1.70.466
2h96893Mitogen-activated protein kinase 82.7.11.240.466
2r7b2533-phosphoinositide-dependent protein kinase 12.7.11.10.466
3ezvEZVCyclin-dependent kinase 22.7.11.220.466
3oyzACOMalate synthase2.3.3.90.466
4z61ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.466
2vu3LZECyclin-dependent kinase 22.7.11.220.465
3b8r887Vascular endothelial growth factor receptor 22.7.10.10.465
4dx9SER_ALA_VAL_THRIntegrin beta-1/0.465
4dx9SER_ALA_VAL_THRIntegrin beta-1-binding protein 1/0.465
4fkv61KCyclin-dependent kinase 22.7.11.220.465
4ix6ADPUncharacterized protein/0.465
5drdATPAurora kinase A2.7.11.10.465
2yyiFAD4-hydroxyphenylacetate 3-monooxygenase oxygenase component1.14.14.90.464
3c50ADPRhodopsin kinase/0.464
5c88COAN-alpha-acetyltransferase/0.464
1eioGCHGastrotropin/0.463
2xa4AZ5Tyrosine-protein kinase JAK2/0.463
3kn5ANPRibosomal protein S6 kinase alpha-52.7.11.10.463
3qu0X40Cyclin-dependent kinase 22.7.11.220.463
3sufSUEPolyprotein/0.463
4enxZ20Serine/threonine-protein kinase pim-12.7.11.10.463
4fkw62KCyclin-dependent kinase 22.7.11.220.463
4inb1F6Gag protein/0.463
4lyn1YGCyclin-dependent kinase 22.7.11.220.463
1dubCAAEnoyl-CoA hydratase, mitochondrial4.2.1.170.462
1k74544Peroxisome proliferator-activated receptor gamma/0.462
1knuYPAPeroxisome proliferator-activated receptor gamma/0.462
2xc3RT8Steroid C26-monooxygenase1.14.13.1410.462
2znq401Peroxisome proliferator-activated receptor delta/0.462
3dxjNE6DNA-directed RNA polymerase subunit beta/0.462
3dxjNE6DNA-directed RNA polymerase subunit beta'/0.462
3rm618ZCyclin-dependent kinase 22.7.11.220.462
3rmf20ZCyclin-dependent kinase 22.7.11.220.462
3w32W32Epidermal growth factor receptor2.7.10.10.462
3zdu38RCyclin-dependent kinase-like 32.7.11.220.462
4a4vYFDPeroxisome proliferator-activated receptor gamma/0.462
4anuEM7Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.462
4dreNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.462
4oxyNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.462
4y8wSTRSteroid 21-hydroxylase/0.462
1uy7PU4Heat shock protein HSP 90-alpha/0.461
2ca0PXICytochrome P450 monooxygenase PikC/0.461
2chz093Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.461
2pmoHMDProtein kinase 7/0.461
2w1hL0FCyclin-dependent kinase 22.7.11.220.461
3oroAGSSerine/threonine protein kinase/0.461
3qrtX14Cyclin-dependent kinase 22.7.11.220.461
4f9mFCMPeroxisome proliferator-activated receptor gamma/0.461
4k110J9Proto-oncogene tyrosine-protein kinase Src2.7.10.20.461
4uyf73BBromodomain-containing protein 2/0.461
2a5uQYTPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.460
2cchATPCyclin-dependent kinase 22.7.11.220.460
2h3wCOACarnitine O-acetyltransferase2.3.1.70.460
2h8hH8HProto-oncogene tyrosine-protein kinase Src2.7.10.20.460
2pr2DG1Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.460
2yfeYFEPeroxisome proliferator-activated receptor gamma/0.460
3gobHXXDdmC/0.460
3inxJZCHeat shock protein HSP 90-alpha/0.460
3r7yZ04Cyclin-dependent kinase 22.7.11.220.460
3s1h56ZCyclin-dependent kinase 22.7.11.220.460
4fuyEK2Mitogen-activated protein kinase 12.7.11.240.460
4gk3L87Ephrin type-A receptor 32.7.10.10.460
4id71G0Activated CDC42 kinase 1/0.460
1idb0DOGag-Pol polyprotein/0.459
2y46MIVMycinamicin IV hydroxylase/epoxidase/0.459
3ddpRC8Cyclin-dependent kinase 22.7.11.220.459
3qtuX44Cyclin-dependent kinase 22.7.11.220.459
3rak03ZCyclin-dependent kinase 22.7.11.220.459
4kikKSAInhibitor of nuclear factor kappa-B kinase subunit beta2.7.11.100.459
1di8DTQCyclin-dependent kinase 22.7.11.220.458
1ke6LS2Cyclin-dependent kinase 22.7.11.220.458
2b55D31Cyclin-dependent kinase 22.7.11.220.458
2ds11CDCyclin-dependent kinase 22.7.11.220.458
2hwrDRDPeroxisome proliferator-activated receptor gamma/0.458
2y6o1N1Ephrin type-A receptor 42.7.10.10.458
2yylFAD4-hydroxyphenylacetate 3-monooxygenase oxygenase component1.14.14.90.458
3eljGS7Mitogen-activated protein kinase 82.7.11.240.458
3i4bZ48Glycogen synthase kinase-3 beta2.7.11.260.458
3nux3NVCyclin-dependent kinase 62.7.11.220.458
3qk0QK0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.458
3sheI85MAP kinase-activated protein kinase 32.7.11.10.458
4c59FEFCyclin-G-associated kinase2.7.11.10.458
5ej9TPP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.458
1bygSTUTyrosine-protein kinase CSK/0.457
1ee0CAA2-pyrone synthase/0.457
1phgMYTCamphor 5-monooxygenase1.14.15.10.457
1zgyBRLPeroxisome proliferator-activated receptor gamma/0.457
2d3mCOA5,7-dihydroxy-2-methylchromone synthase2.3.1.2160.457
2pvlP55Casein kinase II subunit alpha2.7.11.10.457
2yee2ECHeat shock protein HSP 90-alpha/0.457
2zjwREFCasein kinase II subunit alpha2.7.11.10.457
3nup3NUCyclin-dependent kinase 62.7.11.220.457
3qaiXNNKetohexokinase/0.457
3roy22ZCyclin-dependent kinase 22.7.11.220.457
3vspEK8Peroxisome proliferator-activated receptor gamma/0.457
4dtiNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.457
4kzoNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.457
1jipKTN6-deoxyerythronolide B hydroxylase/0.456
2pvnP63Casein kinase II subunit alpha2.7.11.10.456
3bheBZNGag-Pol polyprotein3.4.23.160.456
3ibdCPZCytochrome P450 2B61.14.130.456
3icrFADCoenzyme A disulfide reductase/0.456
4b7sQLECytochrome P450 monooxygenase PikC/0.456
4erwSTUCyclin-dependent kinase 22.7.11.220.456
4hee14RPeroxisome proliferator-activated receptor gamma/0.456
4m87NADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.456
4tuvCPZCytochrome P450 1191.140.456
5ab6CAANonspecific lipid-transfer protein, putative/0.456
5ifiPRXAcetyl-coenzyme A synthetase/0.456
1h1r6CPCyclin-dependent kinase 22.7.11.220.455
1ppjANYCytochrome b/0.455
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.455
1u54ACPActivated CDC42 kinase 1/0.455
2dcnADP2-keto-3-deoxy-gluconate kinase/0.455
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.455
2om9AJAPeroxisome proliferator-activated receptor gamma/0.455
3gbk2PQPeroxisome proliferator-activated receptor gamma/0.455
3gbuATPUncharacterized sugar kinase PH14592.7.10.455
3h0aD30Peroxisome proliferator-activated receptor gamma/0.455
3kgaLX9MAP kinase-activated protein kinase 22.7.11.10.455
3kytHC2Nuclear receptor ROR-gamma/0.455
3le62BZCyclin-dependent kinase 22.7.11.220.455
3oewNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.455
3r8lZ30Cyclin-dependent kinase 22.7.11.220.455
3vn9ANKDual specificity mitogen-activated protein kinase kinase 62.7.12.20.455
3w4yFADMitochondrial FAD-linked sulfhydryl oxidase ERV11.8.3.20.455
3zuyTCHTransporter/0.455
4acc7YGGlycogen synthase kinase-3 beta2.7.11.260.455
4fw8NAI3-oxoacyl-(Acyl-carrier-protein) reductase/0.455
4nmdFDABifunctional protein PutA/0.455
1hvsA77Gag-Pol polyprotein/0.454
1oiyN41Cyclin-dependent kinase 22.7.11.220.454
1urwI1PCyclin-dependent kinase 22.7.11.220.454
1vrwNAIEnoyl-ACP reductase/0.454
1zmdNAIDihydrolipoyl dehydrogenase, mitochondrial1.8.1.40.454
2ath3EAPeroxisome proliferator-activated receptor gamma/0.454
2dwbANPAurora kinase A2.7.11.10.454
2gdo12CSerine/threonine-protein kinase Chk12.7.11.10.454
2i4pDRHPeroxisome proliferator-activated receptor gamma/0.454
2w9sTOPDihydrofolate reductase type 1 from Tn40031.5.1.30.454
2yekEAMBromodomain-containing protein 2/0.454
3dgaNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.454
3tqhNDPQuinone oxidoreductase/0.454
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.454
4efuEFUHeat shock protein HSP 90-alpha/0.454
4z64ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.454
1ml3NADGlyceraldehyde-3-phosphate dehydrogenase, glycosomal1.2.1.120.453
1oi9N20Cyclin-dependent kinase 22.7.11.220.453
1owpFADDeoxyribodipyrimidine photo-lyase4.1.99.30.453
1wvgAPRCDP-glucose 4,6-dehydratase4.2.1.450.453
2q59240Peroxisome proliferator-activated receptor gamma/0.453
3il1B5DGlutamate receptor 2/0.453
3jswJARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.453
3ofm4B0Casein kinase II subunit alpha'2.7.11.10.453
3q0gCOAProbable enoyl-CoA hydratase echA84.2.1.170.453
4cfnJYMCyclin-dependent kinase 22.7.11.220.453
4fkr45KCyclin-dependent kinase 22.7.11.220.453
4h3c0YZDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.453
4kip1R9Mitogen-activated protein kinase 14/0.453
4mcv29KProto-oncogene tyrosine-protein kinase Src2.7.10.20.453
4xcvNDPProbable hydroxyacid dehydrogenase protein/0.453
1gii1PUCyclin-dependent kinase 22.7.11.220.452
1ie4T44Transthyretin/0.452
1pdhFASp-hydroxybenzoate hydroxylase/0.452
1pg3PRXAcetyl-coenzyme A synthetase/0.452
2fwzH71Heat shock protein HSP 90-alpha/0.452
2gtk208Peroxisome proliferator-activated receptor gamma/0.452
2uxuNARHTH-type transcriptional regulator TtgR/0.452
3at4CCKCasein kinase II subunit alpha2.7.11.10.452
3dds26BGlycogen phosphorylase, liver form2.4.1.10.452
3eb0DRKUncharacterized protein/0.452
3gw9VNILanosterol 14-alpha-demethylase/0.452
3rpv26ZCyclin-dependent kinase 22.7.11.220.452
4fhh0U3Vitamin D3 receptor A/0.452
4fklCK2Cyclin-dependent kinase 22.7.11.220.452
4k181OBSerine/threonine-protein kinase pim-12.7.11.10.452
4nbwNADShort-chain dehydrogenase/reductase SDR/0.452
1jioDEB6-deoxyerythronolide B hydroxylase/0.451
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.451
1pxmCK5Cyclin-dependent kinase 22.7.11.220.451
1s9eADBGag-Pol polyprotein2.7.7.490.451
1xny191Propionyl-CoA carboxylase complex B subunit/0.451
2b9fADPMitogen-activated protein kinase FUS32.7.11.240.451
2iebZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.451
2q4bNAPUncharacterized protein At5g02240/0.451
2znoS44Peroxisome proliferator-activated receptor gamma/0.451
3a14NDP1-deoxy-D-xylulose 5-phosphate reductoisomerase/0.451
3clyACPFibroblast growth factor receptor 2/0.451
3hdmMMGSerine/threonine-protein kinase Sgk12.7.11.10.451
3hz5Z64Heat shock protein HSP 90-alpha/0.451
3lshFADPyranose 2-oxidase/0.451
3vn2TLSPeroxisome proliferator-activated receptor gamma/0.451
3vsoEK1Peroxisome proliferator-activated receptor gamma/0.451
4dit0KDGlycogen synthase kinase-3 beta2.7.11.260.451
4fod0UVALK tyrosine kinase receptor2.7.10.10.451
4hvi19STyrosine-protein kinase JAK32.7.10.20.451
4nkvAERSteroid 17-alpha-hydroxylase/17,20 lyase/0.451
4oh4ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.451
4trnNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.451
1bdlIM1Gag-Pol polyprotein3.4.23.160.450
1e8xATPPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.450
1i7iAZ2Peroxisome proliferator-activated receptor gamma/0.450
2c5yMTWCyclin-dependent kinase 22.7.11.220.450
2q5p241Peroxisome proliferator-activated receptor gamma/0.450
3a60STURibosomal protein S6 kinase beta-12.7.11.10.450
3orkAGSSerine/threonine protein kinase/0.450
3rkb12ZCyclin-dependent kinase 22.7.11.220.450
3rni21ZCyclin-dependent kinase 22.7.11.220.450
3tk3CPZCytochrome P450 2B41.14.14.10.450
3tkh07SSerine/threonine-protein kinase Chk12.7.11.10.450
4a9nA9NBromodomain-containing protein 2/0.450
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.450
1ndeMONEstrogen receptor beta/0.449
1nyxDRFPeroxisome proliferator-activated receptor gamma/0.449
1u4dDBQActivated CDC42 kinase 1/0.449
2p20PRXAcetyl-coenzyme A synthetase/0.449
2vd5BI8Myotonin-protein kinase2.7.11.10.449
3b895GP16S rRNA methylase/0.449
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.449
3iok1P6Tyrosine-protein kinase JAK2/0.449
3l0lHC3Nuclear receptor ROR-gamma/0.449
3t14FADSulfide-quinone reductase/0.449
4eomATPCyclin-dependent kinase 22.7.11.220.449
4ib4ERM5-hydroxytryptamine receptor 2B/0.449
4irnFADAnaB/0.449
4ja81K9Isocitrate dehydrogenase [NADP], mitochondrial1.1.1.420.449
4kbk1QGCasein kinase I isoform delta2.7.11.10.449
4nakPBQ2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, chloroplastic2.7.7.600.449
4nmbFADBifunctional protein PutA/0.449
1bxqPP8Penicillopepsin-13.4.23.200.448
1cg6MTAS-methyl-5'-thioadenosine phosphorylase/0.448
1ia3TQ5Dihydrofolate reductase1.5.1.30.448
1meuDMPGag-Pol polyprotein3.4.23.160.448
1n83CLRNuclear receptor ROR-alpha/0.448
1owmFADDeoxyribodipyrimidine photo-lyase4.1.99.30.448
1ownFADDeoxyribodipyrimidine photo-lyase4.1.99.30.448
1uy9PU6Heat shock protein HSP 90-alpha/0.448
2brnDF1Serine/threonine-protein kinase Chk12.7.11.10.448
2cig1DGDihydrofolate reductase1.5.1.30.448
2qd4CHDFerrochelatase, mitochondrial4.99.1.10.448
2zv2609Calcium/calmodulin-dependent protein kinase kinase 22.7.11.170.448
3a62STURibosomal protein S6 kinase beta-12.7.11.10.448
3bbtFMMReceptor tyrosine-protein kinase erbB-42.7.10.10.448
3bc3OPTCathepsin L13.4.22.150.448
3bhh5CPCalcium/calmodulin-dependent protein kinase type II subunit beta2.7.11.170.448
3o0iP54Heat shock protein HSP 90-alpha/0.448
3qruX19Cyclin-dependent kinase 22.7.11.220.448
4lopSB4Mitogen-activated protein kinase 14/0.448
4nbtNAD3-oxoacyl-[acyl-carrier-protein] reductase/0.448
4otpADPSerine/threonine-protein kinase RIO12.7.11.10.448
5dr6SKEAurora kinase A2.7.11.10.448
5dt3ATPAurora kinase A2.7.11.10.448
1h0w207Cyclin-dependent kinase 22.7.11.220.447
1n4vFADCholesterol oxidase1.1.3.60.447
1pxpCK8Cyclin-dependent kinase 22.7.11.220.447
1qiqACCIsopenicillin N synthase1.21.3.10.447
1y4lSVRBasic phospholipase A2 homolog 2/0.447
1y60H4M5,6,7,8-tetrahydromethanopterin hydro-lyase4.2.1.1470.447
1ykr628Cyclin-dependent kinase 22.7.11.220.447
2b52D42Cyclin-dependent kinase 22.7.11.220.447
2eleSAHDiphthine synthase/0.447
2g2zCOZMalonyl CoA-acyl carrier protein transacylase2.3.1.390.447
2iw6QQ2Cyclin-dependent kinase 22.7.11.220.447
2npaMMBPeroxisome proliferator-activated receptor alpha/0.447
2owkSAHDiphthine synthase/0.447
2p2qPRXAcetyl-coenzyme A synthetase/0.447
2uztSS3cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.447
2y1oT26UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.447
2zoq5IDMitogen-activated protein kinase 32.7.11.240.447
3bbrBHYGlutamate receptor 2/0.447
3d8bADPFidgetin-like protein 13.6.40.447
3iphG11Mitogen-activated protein kinase 14/0.447
3mdvCL6Cholesterol 24-hydroxylase/0.447
3oeyNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.447
3otfCMPPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4/0.447
3p7nFMNLight-activated DNA-binding protein EL222/0.447
3poz03PEpidermal growth factor receptor2.7.10.10.447
3rk507ZCyclin-dependent kinase 22.7.11.220.447
3unk0BYCyclin-dependent kinase 22.7.11.220.447
3zc6VFCTyrosine-protein kinase JAK32.7.10.20.447
4bcoT6QCyclin-dependent kinase 22.7.11.220.447
4bzo676Serine/threonine-protein kinase pim-12.7.11.10.447
4c62XWWTyrosine-protein kinase JAK2/0.447
4foc0UUALK tyrosine kinase receptor2.7.10.10.447
4mvfSTUCalcium-dependent protein kinase 22.7.11.10.447
4z63ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.447
1fm9570Peroxisome proliferator-activated receptor gamma/0.446
1lsjNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.446
1mruAGSSerine/threonine-protein kinase PknB2.7.11.10.446
1muiAB1Protease/0.446
1sr7MOFProgesterone receptor/0.446
2d52COA5,7-dihydroxy-2-methylchromone synthase2.3.1.2160.446
2ghlLIBMitogen-activated protein kinase 14/0.446
2objVRVSerine/threonine-protein kinase pim-12.7.11.10.446
2ou2ACOHistone acetyltransferase KAT5/0.446
2ovhAS0Progesterone receptor/0.446
2q46NAPUncharacterized protein At5g02240/0.446
2w05FRTCyclin-dependent kinase 22.7.11.220.446
3au8NDP1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic1.1.1.2670.446
3cpsNADGlyceraldehyde-3-phosphate dehydrogenase/0.446
3ibeL64Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
3pxkPXKFocal adhesion kinase 12.7.10.20.446
3pxyJWSCyclin-dependent kinase 22.7.11.220.446
3qa2XNAKetohexokinase/0.446
3r2b05BMAP kinase-activated protein kinase 22.7.11.10.446
3th8TH9Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.446
3u2lFADFAD-linked sulfhydryl oxidase ALR1.8.3.20.446
3w5rLOAVitamin D3 receptor/0.446
4acm7YGCyclin-dependent kinase 22.7.11.220.446
4anv751Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
4dtaADNAPH(2'')-Id/0.446
4ejh0QACytochrome P450 2A131.14.14.10.446
4ejvLCLTranscriptional regulator TcaR/0.446
4emaBRLPeroxisome proliferator-activated receptor gamma/0.446
4hgl0YOCasein kinase I isoform gamma-32.7.11.10.446
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.446
4j95ACPFibroblast growth factor receptor 2/0.446
4xumIMNPeroxisome proliferator-activated receptor gamma/0.446
5e8ySTUTGF-beta receptor type-22.7.11.300.446
1hvlA76Gag-Pol polyprotein/0.445
1i7gAZ2Peroxisome proliferator-activated receptor alpha/0.445
1xjdSTUProtein kinase C theta type2.7.11.130.445
1zsnTN2Enoyl-ACP reductase/0.445
2bfyH1NAurora kinase B-A2.7.11.10.445
2cdz23DSerine/threonine-protein kinase PAK 42.7.11.10.445
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.445
2uxpCLMHTH-type transcriptional regulator TtgR/0.445
2vwpNDPGlucose 1-dehydrogenase/0.445
2xj1XJ1Serine/threonine-protein kinase pim-12.7.11.10.445
3cylVITBasic phospholipase A2 homolog piratoxin-2/0.445
3f1kNAPUncharacterized oxidoreductase YciK10.445
3nieANPMitogen-activated protein kinase/0.445
3r7iX9ICyclin-dependent kinase 22.7.11.220.445
3rk708ZCyclin-dependent kinase 22.7.11.220.445
3unj0BXCyclin-dependent kinase 22.7.11.220.445
4a4wYFBPeroxisome proliferator-activated receptor gamma/0.445
4bl1ANPMaternal embryonic leucine zipper kinase2.7.11.10.445
4c58824Cyclin-G-associated kinase2.7.11.10.445
4e4qRRHPeroxisome proliferator-activated receptor gamma/0.445
4ewn0VRImidazole glycerol phosphate synthase subunit HisF4.1.30.445
4fxy0W2Neurolysin, mitochondrial3.4.24.160.445
4oj4DIFPeroxisome proliferator-activated receptor gamma/0.445
4p8rNADGlyceraldehyde-3-phosphate dehydrogenase/0.445
4r20AERCytochrome P450 family 17 polypeptide 2/0.445
4yzcSTUSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.445
1bxkNADdTDP-glucose 4,6-dehydratase 2/0.444
1n49RITGag-Pol polyprotein3.4.23.160.444
1pmeSB2Mitogen-activated protein kinase 12.7.11.240.444
1t3r017Gag-Pol polyprotein3.4.23.160.444
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.444
2gs7ANPEpidermal growth factor receptor2.7.10.10.444
2j7t274Serine/threonine-protein kinase 102.7.11.10.444
2pd7FADVivid PAS protein VVD/0.444
2q8sL92Peroxisome proliferator-activated receptor gamma/0.444
2vwqNAPGlucose 1-dehydrogenase/0.444
2x7hPFNProstaglandin reductase 310.444
2x8iX8ISerine/threonine-protein kinase Chk12.7.11.10.444
2xbjXBJSerine/threonine-protein kinase Chk22.7.11.10.444
3cblSTUTyrosine-protein kinase Fes/Fps2.7.10.20.444
3gytDL4Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.444
3hllI45Mitogen-activated protein kinase 14/0.444
3iqzH4MF420-dependent methylenetetrahydromethanopterin dehydrogenase1.5.98.10.444
3kvxFMYMitogen-activated protein kinase 102.7.11.240.444
3qaaG04Gag-Pol polyprotein3.4.23.160.444
3r354CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.444
3wecAUICytochrome P450/0.444
4ful0VUPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
4fv6E57Mitogen-activated protein kinase 12.7.11.240.444
4gxs0YSGlutamate receptor 2/0.444
4n57ADPAPH(2'')-Id/0.444
1aq1STUCyclin-dependent kinase 22.7.11.220.443
1bifAGS6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 42.7.1.1050.443
1fm4DXCMajor pollen allergen Bet v 1-L/0.443
1j1bANPGlycogen synthase kinase-3 beta2.7.11.260.443
1k6tXN1Gag-Pol polyprotein3.4.23.160.443
1qmfKEFPenicillin-binding protein 2x/0.443
1u3cFADCryptochrome-1/0.443
1uh5TCLEnoyl-ACP reductase/0.443
2aclREARetinoic acid receptor RXR-alpha/0.443
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
2q61SF1Peroxisome proliferator-activated receptor gamma/0.443
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.443
2wyvNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.443
3ad9NADSubunit alpha of sarocosine oxidase/0.443
3dd125DGlycogen phosphorylase, liver form2.4.1.10.443
3dfcANPDeath-associated protein kinase 12.7.11.10.443
3ezrEZRCyclin-dependent kinase 22.7.11.220.443
3ggfGVDSerine/threonine-protein kinase 26/0.443
3lltANPProtein serine/threonine kinase-1/0.443
3tea4CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.443
4cqlNADEstradiol 17-beta-dehydrogenase 81.1.1.620.443
4fjz4FJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
4fuxE75Mitogen-activated protein kinase 12.7.11.240.443
4ge40KEKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.443
4gub0Y4Casein kinase II subunit alpha2.7.11.10.443
4y12AGSSerine/threonine-protein kinase PknG2.7.11.10.443
5dpvSKEAurora kinase A2.7.11.10.443
1h1wATP3-phosphoinositide-dependent protein kinase 12.7.11.10.442
1hihC20Gag-Pol polyprotein/0.442
1nhgTCLEnoyl-ACP reductase/0.442
1owoFADDeoxyribodipyrimidine photo-lyase4.1.99.30.442
1tl1H18Gag-Pol polyprotein2.7.7.490.442
1xddAAYIntegrin alpha-L/0.442
1z1hHBBGag-Pol polyprotein3.4.23.160.442
1zidZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.442
2c27ACOMycothiol acetyltransferase2.3.1.1890.442
2ejzSAHDiphthine synthase/0.442
2fvdLIACyclin-dependent kinase 22.7.11.220.442
2hydADPPutative multidrug export ATP-binding/permease protein SAV18663.6.30.442
2j14GNIPeroxisome proliferator-activated receptor delta/0.442
2yeiXQIHeat shock protein HSP 90-alpha/0.442
3e8nVRADual specificity mitogen-activated protein kinase kinase 12.7.12.20.442
3g51ANPRibosomal protein S6 kinase alpha-32.7.11.10.442
3nynSGVG protein-coupled receptor kinase 62.7.11.160.442
3pe6ZYHMonoglyceride lipase/0.442
3qlrNDPDihydrofolate reductase1.5.1.30.442
3t99ADPInositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2/0.442
3vt9YI4Vitamin D3 receptor/0.442
4aknS5BBromodomain-containing protein 2/0.442
4awiAQ2Mitogen-activated protein kinase 82.7.11.240.442
4bqh9VUUDP-N-acetylglucosamine pyrophosphorylase, putative/0.442
4eji0QACytochrome P450 2A131.14.14.10.442
4ftn2HKSerine/threonine-protein kinase Chk12.7.11.10.442
4hyh1AMSerine/threonine-protein kinase Chk12.7.11.10.442
4idv13VMitogen-activated protein kinase kinase kinase 142.7.11.250.442
4im2BX7Serine/threonine-protein kinase TBK12.7.11.10.442
4jq8KJ8Epidermal growth factor receptor2.7.10.10.442
4l521ULMitogen-activated protein kinase kinase kinase 72.7.11.250.442
4o2bLOCTubulin beta-2B chain/0.442
4xuhSFIPeroxisome proliferator-activated receptor gamma/0.442
4zohFADPutative oxidoreductase FAD-binding subunit/0.442
5a9sNAPPutative dehydrogenase/0.442
1hdrNADDihydropteridine reductase1.5.1.340.441
1m78NDPDihydrofolate reductase1.5.1.30.441
1mq4ADPAurora kinase A2.7.11.10.441
1osvCHCBile acid receptor/0.441
1pyxANPGlycogen synthase kinase-3 beta2.7.11.260.441
1yw2PGJMitogen-activated protein kinase 14/0.441
2br1PFPSerine/threonine-protein kinase Chk12.7.11.10.441
2c54NADGDP-mannose 3,5-epimerase5.1.3.180.441
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.441
2emuSAHDiphthine synthase/0.441
2f3kRO1Protease/0.441
2f5zFADDihydrolipoyl dehydrogenase, mitochondrial1.8.1.40.441
2h55DZ8Heat shock protein HSP 90-alpha/0.441
2itnANPEpidermal growth factor receptor2.7.10.10.441
2j5xGSPADP-ribosylation factor 6/0.441
2jj2ANPATP synthase subunit beta, mitochondrial3.6.3.140.441
2rbeNDPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.441
2wpxACOOrf14/0.441
2wxvWXVCyclin-dependent kinase 22.7.11.220.441
2xtzGSPGuanine nucleotide-binding protein alpha-1 subunit/0.441
3a99ANPSerine/threonine-protein kinase pim-12.7.11.10.441
3aw9NADNAD-dependent epimerase/dehydratase/0.441
3dt1P40Mitogen-activated protein kinase 14/0.441
3em6017Gag-Pol polyprotein3.4.23.160.441
3fwjCAMCamphor 5-monooxygenase1.14.15.10.441
3irxUDRGag-Pol polyprotein2.7.7.490.441
3kduNKSPeroxisome proliferator-activated receptor alpha/0.441
3kpkFADSulfide-quinone reductase/0.441
3lqfNADGalactitol dehydrogenase/0.441
3n4mCMPcAMP-activated global transcriptional regulator CRP/0.441
3nyg2NCGag-Pol polyprotein3.4.23.160.441
3oom507Activin receptor type-12.7.11.300.441
3p2oNADBifunctional protein FolD/0.441
3qtxX43Cyclin-dependent kinase 22.7.11.220.441
3rk909ZCyclin-dependent kinase 22.7.11.220.441
3sc13S13-phosphoinositide-dependent protein kinase 12.7.11.10.441
3sdkP3NProteasome subunit beta type-53.4.25.10.441
3sdkP3NProteasome subunit beta type-63.4.25.10.441
3sw418KCyclin-dependent kinase 22.7.11.220.441
3u8hBHPPhospholipase A2, membrane associated/0.441
3umpATPATP-dependent 6-phosphofructokinase isozyme 22.7.1.110.441
3zhqTPPMultifunctional 2-oxoglutarate metabolism enzyme1.2.4.20.441
4aqc88ATyrosine-protein kinase JAK2/0.441
4bcmT7ZCyclin-dependent kinase 22.7.11.220.441
4btjATPTau-tubulin kinase 12.7.11.10.441
4fl2ANPTyrosine-protein kinase SYK2.7.10.20.441
4fvqATPTyrosine-protein kinase JAK2/0.441
4h8nNDPNADPH-dependent conjugated polyketone reductase C2/0.441
4ly91YYGlucokinase regulatory protein/0.441
5hwqCAAHydroxymethylglutaryl-CoA synthase/0.441
1a4iNDPC-1-tetrahydrofolate synthase, cytoplasmic1.5.1.50.440
1gih1PUCyclin-dependent kinase 22.7.11.220.440
1h1s4SPCyclin-dependent kinase 22.7.11.220.440
1ie3NADMalate dehydrogenase/0.440
1k6mAGS6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 12.7.1.1050.440
1qbrXV6Gag-Pol polyprotein3.4.23.160.440
1t88CAMCamphor 5-monooxygenase1.14.15.10.440
1uyhPU0Heat shock protein HSP 90-alpha/0.440
1vruAAPGag-Pol polyprotein2.7.7.490.440
1yb5NAPQuinone oxidoreductase1.6.5.50.440
2cej1AHPol protein/0.440
2p4yC03Peroxisome proliferator-activated receptor gamma/0.440
2vtpLZ9Cyclin-dependent kinase 22.7.11.220.440
2xchCKG3-phosphoinositide-dependent protein kinase 12.7.11.10.440
2xngA0HAurora kinase A2.7.11.10.440
2ycsNXPSerine/threonine-protein kinase Chk22.7.11.10.440
3adaNADSubunit alpha of sarocosine oxidase/0.440
3el4ROCGag-Pol polyprotein3.4.23.160.440
3juhANPCasein kinase II subunit alpha2.7.11.10.440
3lfqA28Cyclin-dependent kinase 22.7.11.220.440
3lsiFADPyranose 2-oxidase/0.440
3lzu017Gag-Pol polyprotein3.4.23.160.440
3nxe2NCProtease/0.440
3okxSAMS-adenosyl-L-methionine-binding protein RPA0152/0.440
3r7uX96Cyclin-dependent kinase 22.7.11.220.440
3rps4B0Casein kinase II subunit alpha2.7.11.10.440
3vt5YI2Vitamin D3 receptor/0.440
3zc3NAPFerredoxin--NADP reductase1.18.1.20.440
4a2jAS0Progesterone receptor/0.440
4bgq38RCyclin-dependent kinase-like 52.7.11.220.440
4ccbOFGALK tyrosine kinase receptor2.7.10.10.440
4ce3L4VATP-dependent molecular chaperone HSP82/0.440
4eilCB3Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.440
4fv8E63Mitogen-activated protein kinase 12.7.11.240.440
4l9zCOAL-malyl-CoA/beta-methylmalyl-CoA lyase4.1.3.240.440
4ogrADNCyclin-dependent kinase 92.7.11.220.440
4xgxADPFAD:protein FMN transferase/0.440
5ab7MLCNonspecific lipid-transfer protein, putative/0.440