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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1z0uNAPNAD kinase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1z0uNAPNAD kinase/1.000
1rdwLARActin, alpha skeletal muscle/0.503
1bw9NADPhenylalanine dehydrogenase/0.498
2cy0NAPShikimate dehydrogenase (NADP(+))/0.491
4yqfGDPSeptin-9/0.491
2cibCM6Lanosterol 14-alpha demethylase1.14.13.700.488
4oqyNDP(S)-imine reductase/0.486
4l4xNDPAmphI/0.484
2ch6ADPN-acetyl-D-glucosamine kinase2.7.1.590.483
3sp6IL2Peroxisome proliferator-activated receptor alpha/0.483
5d7qAR6NAD-dependent protein deacetylase sirtuin-23.5.10.482
3rueNADUDP-N-acetylglucosamine 4-epimerase/0.481
4y93746Tyrosine-protein kinase/0.478
3bv2P38Mitogen-activated protein kinase 14/0.477
1rfvADPPyridoxal kinase2.7.1.350.476
2brnDF1Serine/threonine-protein kinase Chk12.7.11.10.476
2cgpCMPcAMP-activated global transcriptional regulator CRP/0.476
5c8wPCGcGMP-dependent protein kinase 22.7.11.120.476
1gcoNADGlucose 1-dehydrogenase1.1.1.470.475
4iqlFMNEnoyl-(Acyl-carrier-protein) reductase II/0.475
1mjaCOAHistone acetyltransferase ESA1/0.474
2f7e2EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.473
3c1y2BADNA integrity scanning protein DisA/0.473
3etdNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.473
3mk6ACOPantothenate kinase 32.7.1.330.473
3a14NDP1-deoxy-D-xylulose 5-phosphate reductoisomerase/0.472
4nxvGDPMitochondrial dynamics protein MID51/0.472
3kjsNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.471
4ewn0VRImidazole glycerol phosphate synthase subunit HisF4.1.30.471
3iocA5DPantothenate synthetase6.3.2.10.470
1u7tNAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.469
2a7r5GPGMP reductase 2/0.468
2ibzUQ6Cytochrome b/0.468
3pndFADFAD:protein FMN transferase/0.468
1j0xNADGlyceraldehyde-3-phosphate dehydrogenase1.2.1.120.467
4bvbAR6NAD-dependent protein deacetylase sirtuin-3, mitochondrial3.5.10.467
1mhtSAHModification methylase HhaI2.1.1.370.466
2cig1DGDihydrofolate reductase1.5.1.30.466
2xhd7T9Glutamate receptor 2/0.466
3ivgFG5Pantothenate synthetase6.3.2.10.466
3wmxNADNAD dependent epimerase/dehydratase/0.466
4nxuADPMitochondrial dynamics protein MID51/0.466
5d3qGDPDynamin-13.6.5.50.466
2g5cNADPrephenate dehydrogenase/0.465
3clyACPFibroblast growth factor receptor 2/0.465
3zxsFADDeoxyribodipyrimidine photolyase-related protein/0.465
4qmzB49Serine/threonine-protein kinase 242.7.11.10.465
1a8pFADFerredoxin--NADP reductase/0.464
1k7fIAVTryptophan synthase alpha chain/0.464
1u0wSTLChalcone synthase 22.3.1.740.464
1ykfNAPNADP-dependent isopropanol dehydrogenase1.1.1.800.464
2b53D23Cyclin-dependent kinase 22.7.11.220.464
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.464
2j5xGSPADP-ribosylation factor 6/0.464
3b895GP16S rRNA methylase/0.464
3oquA8SAbscisic acid receptor PYL9/0.464
4cukNAID-lactate dehydrogenase/0.464
4dbzNDPPutative ketoacyl reductase1.3.10.464
4i02CMPcAMP-activated global transcriptional regulator CRP/0.464
4nd3NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.464
2iyaZIOOleandomycin glycosyltransferase/0.463
3bg7FADPyranose 2-oxidase/0.463
3c212BADNA integrity scanning protein DisA/0.463
3d7kD7KBenzaldehyde lyase/0.463
3rucNADUDP-N-acetylglucosamine 4-epimerase/0.463
4dpwAGSMevalonate diphosphate decarboxylase/0.463
1gthFADDihydropyrimidine dehydrogenase [NADP(+)]1.3.1.20.462
1u3dFADCryptochrome-1/0.462
1uamSAHtRNA (guanine-N(1)-)-methyltransferase2.1.1.2280.462
2nnlNAPDihydroflavonol 4-reductase1.1.1.2190.462
2o12FMNChorismate synthase/0.462
2y9qANPMitogen-activated protein kinase 12.7.11.240.462
3bhrTHGThymidylate synthase/0.462
3nglNAPBifunctional protein FolD/0.462
4a9rRU5Serine/threonine-protein kinase Chk22.7.11.10.462
4an4DUDPutative glycosyl transferase/0.462
2e9v85ASerine/threonine-protein kinase Chk12.7.11.10.461
3sjhLARActin, alpha skeletal muscle/0.461
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.461
4h8nNDPNADPH-dependent conjugated polyketone reductase C2/0.461
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.461
4jk4DIUSerum albumin/0.461
4r1lADPPhenylacetate-coenzyme A ligase/0.461
3cinNADMyo-inositol-1-phosphate synthase-related protein/0.460
3ndrNADPyridoxal 4-dehydrogenase1.1.1.1070.460
3orfNADDihydropteridine reductase1.5.1.340.460
3s1dZIRCytokinin dehydrogenase 11.5.99.120.460
4egbNADdTDP-glucose 4,6-dehydratase/0.460
4hxyNDPPlm1/0.460
4yau2AMNADPH--cytochrome P450 reductase/0.460
1fy7COAHistone acetyltransferase ESA1/0.459
2g25TDKPyruvate dehydrogenase E1 component1.2.4.10.459
2g76NADD-3-phosphoglycerate dehydrogenase1.1.1.950.459
2rkvZBATrichothecene 3-O-acetyltransferase/0.459
2wo7ASVIsopenicillin N synthase1.21.3.10.459
4a61ANPPlasmid segregation protein ParM/0.459
1dhiMTXDihydrofolate reductase1.5.1.30.458
1omoNADAlanine dehydrogenase/0.458
2pr2DG1Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.458
2q0uLABActin, alpha skeletal muscle/0.458
2wyvNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.458
3gqvNAPEnoyl reductase LovC10.458
3jvvACPTwitching mobility protein/0.458
3uf6CODLmo1369 protein/0.458
4mk029XBeta-adrenergic receptor kinase 12.7.11.150.458
5a3cNADSIR2 family protein/0.458
1hw5CMPcAMP-activated global transcriptional regulator CRP/0.457
1k7l544Peroxisome proliferator-activated receptor alpha/0.457
1lbcCYZGlutamate receptor 2/0.457
1qiqACCIsopenicillin N synthase1.21.3.10.457
2a1mCAMCamphor 5-monooxygenase1.14.15.10.457
2a1oCAMCamphor 5-monooxygenase1.14.15.10.457
3q5kD1UHeat shock protein 83-1/0.457
5eccNAPDehydrofolate reductase type I/0.457
1h2bNAJNAD-dependent alcohol dehydrogenase/0.456
2a1nCAMCamphor 5-monooxygenase1.14.15.10.456
2ii6C5PAlpha-2,3/2,6-sialyltransferase/sialidase/0.456
2o98FSC14-3-3-like protein C/0.456
2qtcTDKPyruvate dehydrogenase E1 component1.2.4.10.456
2y60M8FIsopenicillin N synthase1.21.3.10.456
3clbNAPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.456
3d84NDPDihydrofolate reductase1.5.1.30.456
3dheANDEstradiol 17-beta-dehydrogenase 11.1.1.620.456
4djaFAD(6-4) photolyase/0.456
4kl9NDPDihydrofolate reductase1.5.1.30.456
4u0oMTALipoyl synthase 2/0.456
1phePIYCamphor 5-monooxygenase1.14.15.10.455
2pciSAHDiphthine synthase/0.455
3mdmFJZCholesterol 24-hydroxylase/0.455
3sfdFADSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial/0.455
4c04SFGProtein arginine N-methyltransferase 6/0.455
4fv3EK6Mitogen-activated protein kinase 12.7.11.240.455
4plpNADHomospermidine synthase2.5.1.440.455
1fxsNAPGDP-L-fucose synthase/0.454
1llqNADNAD-dependent malic enzyme, mitochondrial1.1.1.380.454
1rwbNADGlucose 1-dehydrogenase1.1.1.470.454
1z7eUGABifunctional polymyxin resistance protein ArnA/0.454
2dr3ADPUPF0273 protein PH0284/0.454
2dwpACP6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 32.7.1.1050.454
2fznFADBifunctional protein PutA1.5.5.20.454
2h12CMXCitrate synthase/0.454
2vwhNAPGlucose 1-dehydrogenase/0.454
3b9oFMNAlkane monoxygenase/0.454
3h3sH15Collagen type IV alpha-3-binding protein/0.454
3toxNAPPutative oxidoreductase/0.454
4jia1K3Tyrosine-protein kinase JAK2/0.454
4l6gCNL1,8-cineole 2-endo-monooxygenase1.14.13.1560.454
4nd2A3DLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.454
4xgxADPFAD:protein FMN transferase/0.454
5jlaNADPutative short-chain dehydrogenase/reductase/0.454
5k5zANPUncharacterized protein/0.454
1bsvNDPGDP-L-fucose synthase/0.453
1dhrNADDihydropteridine reductase1.5.1.340.453
1f20FADNitric oxide synthase, brain1.14.13.390.453
1rp0AHZThiamine thiazole synthase, chloroplastic/0.453
2g2zCOZMalonyl CoA-acyl carrier protein transacylase2.3.1.390.453
3dmhSAMProbable ribosomal RNA small subunit methyltransferase/0.453
3ii43IIDihydrolipoyl dehydrogenase1.8.1.40.453
3ioeA7DPantothenate synthetase6.3.2.10.453
3oafOAGDihydrofolate reductase1.5.1.30.453
3v5w8PRBeta-adrenergic receptor kinase 12.7.11.150.453
4a30QMIGlycylpeptide N-tetradecanoyltransferase/0.453
4ambDUDPutative glycosyl transferase/0.453
4h4uNDPBiphenyl dioxygenase ferredoxin reductase subunit/0.453
4qppSAHProtein arginine N-methyltransferase 6/0.453
4ri1ACOUDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase2.3.1.2020.453
5bxySAHPutative RNA methylase family UPF0020/0.453
1bdmNAXMalate dehydrogenase/0.452
1g4tFTPThiamine-phosphate synthase/0.452
2w2lNADD-mandelate dehydrogenase/0.452
2zcjSAHModification methylase HhaI2.1.1.370.452
3ea0ATPATPase, ParA family/0.452
3l63CAMCamphor 5-monooxygenase1.14.15.10.452
3zbrNAP2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.452
4ek816KCyclin-dependent kinase 22.7.11.220.452
4ewhT77Activated CDC42 kinase 1/0.452
4y9qC2EUncharacterized protein/0.452
1eiiRTLRetinol-binding protein 2/0.451
1mjbACOHistone acetyltransferase ESA1/0.451
2ahcVNLChorismate pyruvate-lyase/0.451
2qs4LY5Glutamate receptor ionotropic, kainate 1/0.451
3fhxPLPPyridoxal kinase2.7.1.350.451
3pm9FADPutative oxidoreductase/0.451
3rufNADUDP-N-acetylglucosamine 4-epimerase/0.451
4ddhMS0Pantothenate synthetase6.3.2.10.451
4tl8AGSCircadian clock protein kinase KaiC2.7.11.10.451
4u8iFDAUDP-galactopyranose mutase/0.451
4z63ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.451
5einNAP[LysW]-L-2-aminoadipate 6-phosphate reductase/0.451
5fsyAR6Uncharacterized protein/0.451
1bzlFADTrypanothione reductase1.8.1.120.450
1u3cFADCryptochrome-1/0.450
1um0FMNChorismate synthase/0.450
1w06W05Isopenicillin N synthase1.21.3.10.450
1xkkFMMEpidermal growth factor receptor2.7.10.10.450
2w3bNDPDihydrofolate reductase1.5.1.30.450
3h89NSXCathepsin L13.4.22.150.450
3mqe416Prostaglandin G/H synthase 21.14.99.10.450
3nnz59WNitric oxide synthase, brain1.14.13.390.450
3r6sCMPCRP-like cAMP-activated global transcriptional regulator/0.450
3ru7NADUDP-N-acetylglucosamine 4-epimerase/0.450
4aa4QC0Mitogen-activated protein kinase 14/0.450
4b1uLABActin, alpha skeletal muscle/0.450
4njoNADD-3-phosphoglycerate dehydrogenase, putative/0.450
4oknNAIL-lactate dehydrogenase A chain1.1.1.270.450
4uxjTTPThymidine kinase/0.450
1bk0ACVIsopenicillin N synthase1.21.3.10.449
1c2tNHSPhosphoribosylglycinamide formyltransferase/0.449
1dg8NDPDihydrofolate reductase1.5.1.30.449
2a94AP0L-lactate dehydrogenase1.1.1.270.449
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.449
2fzmFADBifunctional protein PutA1.5.5.20.449
2ghlLIBMitogen-activated protein kinase 14/0.449
2ivpATPtRNA N6-adenosine threonylcarbamoyltransferase/0.449
2o4cNADErythronate-4-phosphate dehydrogenase/0.449
2qo5CHDFatty acid-binding protein 10-A, liver basic/0.449
2wdzNADGalactitol dehydrogenase/0.449
2x19GTPGTP-binding nuclear protein GSP1/CNR1/0.449
3kjrNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.449
3mqgACOLipopolysaccharides biosynthesis acetyltransferase/0.449
3rnnRNNGlutamate receptor 2/0.449
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.449
4c9oCAMCytochrome P450/0.449
4gyzD5MTyrosyl-DNA phosphodiesterase 23.1.40.449
4k6fNAPPutative Acetoacetyl-CoA reductase/0.449
4ng5NAJAlcohol dehydrogenase E chain1.1.1.10.449
4nkeIPEFarnesyl pyrophosphate synthase2.5.1.100.449
1ae1NAPTropinone reductase 1/0.448
1dliUDXUDP-glucose 6-dehydrogenase/0.448
1ebuNDAHomoserine dehydrogenase1.1.1.30.448
1h73ANPHomoserine kinase2.7.1.390.448
1khhSAHGuanidinoacetate N-methyltransferase2.1.1.20.448
1mj9COAHistone acetyltransferase ESA1/0.448
1o76CAMCamphor 5-monooxygenase1.14.15.10.448
1p44NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.448
1svlADPLarge T antigen3.6.40.448
1tj2FADBifunctional protein PutA1.5.5.20.448
2db3ANPATP-dependent RNA helicase vasa, isoform A3.6.4.130.448
2dteNAIGlucose 1-dehydrogenase related protein/0.448
2ozuACOHistone acetyltransferase KAT6A/0.448
2qtrNXXProbable nicotinate-nucleotide adenylyltransferase/0.448
3d8bADPFidgetin-like protein 13.6.40.448
3isjA8DPantothenate synthetase6.3.2.10.448
3w9rA8SAbscisic acid receptor PYL9/0.448
4ejh0QACytochrome P450 2A131.14.14.10.448
4kqwNAPKetol-acid reductoisomerase (NADP(+))/0.448
4l4dCAMCamphor 5-monooxygenase1.14.15.10.448
4nm9FADBifunctional protein PutA/0.448
4o2bLOCTubulin beta-2B chain/0.448
4yauFADNADPH--cytochrome P450 reductase/0.448
1bpwNADBetaine aldehyde dehydrogenase1.2.1.80.447
1gzuNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.447
1w5tADPORC1-type DNA replication protein 2/0.447
2dpxGDPGTP-binding protein RAD/0.447
2jdtI5ScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.447
2o23NAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.447
2ql6ADPNicotinamide riboside kinase 1/0.447
2ym2FADPhenylacetone monooxygenase1.14.13.920.447
3d5fL41Peroxisome proliferator-activated receptor delta/0.447
3ggoNAIPrephenate dehydrogenase/0.447
3kb1ADPIron-sulfur cluster carrier protein/0.447
3lqfNADGalactitol dehydrogenase/0.447
3p2eSAH16S rRNA (adenine(1408)-N(1))-methyltransferase2.1.1.1800.447
3p97SAMGenome polyprotein2.1.1.560.447
3w2jQRODihydroorotate dehydrogenase (fumarate)1.3.98.10.447
4cvmANPUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase/0.447
4dc0NDPPutative ketoacyl reductase1.3.10.447
4eakATP5'-AMP-activated protein kinase subunit gamma-1/0.447
4eqwCOACoenzyme A disulfide reductase/0.447
4i0bCMPcAMP-activated global transcriptional regulator CRP/0.447
4pd6URINucleoside permease/0.447
4pfpADPUnconventional myosin-VI/0.447
1ahiCHO7-alpha-hydroxysteroid dehydrogenase1.1.1.1590.446
1fmjRTLRetinol dehydratase/0.446
1hb1OCVIsopenicillin N synthase1.21.3.10.446
1kqoDNDNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.446
1scuCOASuccinate--CoA ligase [ADP-forming] subunit alpha6.2.1.50.446
1td2PXLPyridoxal kinase PdxY/0.446
2gblATPCircadian clock protein kinase KaiC2.7.11.10.446
2o1sTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.446
2uxpCLMHTH-type transcriptional regulator TtgR/0.446
2vtoLZ8Cyclin-dependent kinase 22.7.11.220.446
2wotZZGTGF-beta receptor type-12.7.11.300.446
2wueKEK4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase3.7.1.170.446
2x3nFADProbable FAD-dependent monooxygenase/0.446
2zdyADP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial2.7.11.20.446
3eteNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.446
3pb3SAH16S rRNA (adenine(1408)-N(1))-methyltransferase2.1.1.1800.446
3rypCMPcAMP-activated global transcriptional regulator CRP/0.446
3t1tGDPProbable gliding protein mglA/0.446
3u9eCOALmo1369 protein/0.446
4dwvNAJAlcohol dehydrogenase E chain1.1.1.10.446
4fmqANPMitogen-activated protein kinase 12.7.11.240.446
4i22IREEpidermal growth factor receptor2.7.10.10.446
4j57FADThioredoxin reductase 21.8.1.90.446
4k41ATPActin, alpha skeletal muscle/0.446
4q71FADBifunctional protein PutA/0.446
4rf2NAPNADPH dependent R-specific alcohol dehydrogenase/0.446
4xvuATPATPase GET3/0.446
4yvjSFGtRNA (guanine-N(1)-)-methyltransferase2.1.1.2280.446
1unlRRCCyclin-dependent-like kinase 52.7.11.10.445
2dkiFAD3-hydroxybenzoate 4-monooxygenase1.14.13.230.445
2iyfERYOleandomycin glycosyltransferase2.4.10.445
2oz6CMPCyclic AMP receptor-like protein/0.445
2w17I19Cyclin-dependent kinase 22.7.11.220.445
3a0iAJIGlucokinase2.7.1.20.445
3eqlMXPDNA-directed RNA polymerase subunit beta/0.445
3eqlMXPDNA-directed RNA polymerase subunit beta'/0.445
3ey9TDPPyruvate dehydrogenase [ubiquinone]1.2.5.10.445
3gvhNADMalate dehydrogenase/0.445
3hbbNAPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.445
3m42HGFMAP kinase-activated protein kinase 22.7.11.10.445
3nmnPYVAbscisic acid receptor PYL1/0.445
3q3cNADNAD-dependent L-serine dehydrogenase/0.445
3qw2NADMyo-inositol-1-phosphate synthase (Ino1)/0.445
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.445
3rjc06ZCyclin-dependent kinase 22.7.11.220.445
3w32W32Epidermal growth factor receptor2.7.10.10.445
3zuyTCHTransporter/0.445
4a2zVIQGlycylpeptide N-tetradecanoyltransferase/0.445
4a9tA9TSerine/threonine-protein kinase Chk22.7.11.10.445
4jpe1M7Beta-secretase 13.4.23.460.445
4kvzSAHPtnL protein/0.445
4nmdFDABifunctional protein PutA/0.445
4yusFMNFamily 3 adenylate cyclase/0.445
4yvkSFGtRNA (guanine-N(1)-)-methyltransferase2.1.1.2280.445
5cyoGDPSeptin-9/0.445
5hbrCOAAcyl-CoA synthetase (NDP forming)/0.445
1hbvGANGag-Pol polyprotein/0.444
1lb9DNQGlutamate receptor 2/0.444
1nmdATPMajor actin/0.444
1q8wM77cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.444
1zz2B11Mitogen-activated protein kinase 14/0.444
2i7pACOPantothenate kinase 32.7.1.330.444
2jcvNDP1-deoxy-D-xylulose 5-phosphate reductoisomerase/0.444
2oapANPType II secretion system protein (GspE-2)/0.444
2of4979Tyrosine-protein kinase Lck2.7.10.20.444
2oh02PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.444
2q7vFADThioredoxin reductase/0.444
2yyuC5POrotidine 5'-phosphate decarboxylase/0.444
3bnkFMNFlavoredoxin/0.444
3cgeFADCoenzyme A disulfide reductase/0.444
3gubGUBDeath-associated protein kinase 12.7.11.10.444
3h3cP1EProtein-tyrosine kinase 2-beta2.7.10.20.444
3qpvADP6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 32.7.1.1050.444
3umvFADDeoxyribodipyrimidine photo-lyase4.1.99.30.444
3w0qANPHygromycin-B 4-O-kinase2.7.1.1630.444
3zewSTUEphrin type-B receptor 42.7.10.10.444
4f4qFADDecaprenylphosphoryl-beta-D-ribose oxidase/0.444
4gapFADRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.444
4opgFDAConserved Archaeal protein/0.444
4rgqNDPGlycerol-1-phosphate dehydrogenase [NAD(P)+]/0.444
4z64ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.444
5hwsNAP2-dehydropantoate 2-reductase/0.444
1aq1STUCyclin-dependent kinase 22.7.11.220.443
1cgpCMPcAMP-activated global transcriptional regulator CRP/0.443
1d4aFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.443
1h69FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.443
1i8tFADUDP-galactopyranose mutase5.4.99.90.443
1l4gNCNNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase2.4.2.210.443
1nhhANPDNA mismatch repair protein MutL/0.443
1pf9ADP60 kDa chaperonin/0.443
1u4dDBQActivated CDC42 kinase 1/0.443
2gtbAZPOrf1ab polyprotein/0.443
2iviACWIsopenicillin N synthase1.21.3.10.443
2ya3J7V5'-AMP-activated protein kinase subunit gamma-1/0.443
3clrFADElectron transfer flavoprotein subunit alpha/0.443
3fln3FNMitogen-activated protein kinase 14/0.443
3icrFADCoenzyme A disulfide reductase/0.443
3nloJSRNitric oxide synthase, brain1.14.13.390.443
3w2eNADNADH-cytochrome b5 reductase 31.6.2.20.443
4a2aATPCell division protein FtsA/0.443
4g1z0VPVitamin D3 receptor A/0.443
4imoPWZProstaglandin-H2 D-isomerase5.3.99.20.443
4kh0ATPAspartate carbamoyltransferase regulatory chain {ECO:0000256|HAMAP-Rule:MF_00002}/0.443
4li81XQTankyrase-12.4.2.300.443
4nka2K7Fibroblast growth factor receptor 1/0.443
4y9rFADNADPH--cytochrome P450 reductase/0.443
5dbvCOAAldehyde Dehydrogenase/0.443
6cp4CAMCamphor 5-monooxygenase1.14.15.10.443
1bv9XV6Gag-Pol polyprotein3.4.23.160.442
1kvuUPGUDP-glucose 4-epimerase5.1.3.20.442
1lolXMPOrotidine 5'-phosphate decarboxylase4.1.1.230.442
1mc1PCXCarboxyethyl-arginine beta-lactam-synthase6.3.3.40.442
1mvsDTMDihydrofolate reductase1.5.1.30.442
1rbzKT5Trifunctional purine biosynthetic protein adenosine-32.1.2.20.442
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.442
2h2qNAPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.442
2ohjFMNType A flavoprotein FprA10.442
2qbmCAMCamphor 5-monooxygenase1.14.15.10.442
2vzmNRBCytochrome P450 monooxygenase PikC/0.442
2zgzGNPPlasmid segregation protein ParM/0.442
3c15FOKAdenylate cyclase type 2/0.442
3c15FOKAdenylate cyclase type 5/0.442
3c16GSPGuanine nucleotide-binding protein G(s) subunit alpha isoforms short/0.442
3dgaNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.442
3fwiCAMCamphor 5-monooxygenase1.14.15.10.442
3iahNAPPutative oxoacyl-(Acyl carrier protein) reductase/0.442
3imgBZ2Pantothenate synthetase6.3.2.10.442
3t3c017Gag-Pol polyprotein3.4.23.160.442
3tqaNDPDihydrofolate reductase/0.442
3ugc046Tyrosine-protein kinase JAK2/0.442
4e730NRMitogen-activated protein kinase 82.7.11.240.442
4gh5NADShort-chain dehydrogenase/reductase SDR/0.442
4ihl1F514-3-3 protein zeta/delta/0.442
4ug5XFKNitric oxide synthase oxygenase1.14.13.1650.442
4wqmFADToluene-4-monooxygenase electron transfer component1.18.1.30.442
5ar4SB2Receptor-interacting serine/threonine-protein kinase 22.7.11.10.442
5cnsCDPRibonucleoside-diphosphate reductase 1 subunit alpha1.17.4.10.442
1bygSTUTyrosine-protein kinase CSK/0.441
1dyiFOLDihydrofolate reductase1.5.1.30.441
1dz4CAMCamphor 5-monooxygenase1.14.15.10.441
1dz6CAMCamphor 5-monooxygenase1.14.15.10.441
1gilGSPGuanine nucleotide-binding protein G(i) subunit alpha-1/0.441
1nlmUD1UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase/0.441
1rkxNADCDP-D-glucose-4,6-dehydratase/0.441
1tj1FADBifunctional protein PutA1.5.5.20.441
1u4oNDDL-lactate dehydrogenase1.1.1.270.441
1w73NAP2,4-dienoyl-CoA reductase, mitochondrial1.3.1.340.441
2cvjFADThioredoxin reductase related protein/0.441
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.441
2egsSAHDiphthine synthase/0.441
2gdzNAD15-hydroxyprostaglandin dehydrogenase [NAD(+)]1.1.1.1410.441
2hamC33Vitamin D3 receptor/0.441
2uzhCDP2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase/0.441
2vo7M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.441
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.441
3iodA6DPantothenate synthetase6.3.2.10.441
3nugNADPyridoxal 4-dehydrogenase1.1.1.1070.441
3p3zP3ZPutative cytochrome P450/0.441
3pxkPXKFocal adhesion kinase 12.7.10.20.441
3r9uFADThioredoxin reductase/0.441
3t0zATPHeat shock protein HSP 90-alpha/0.441
3uwqU5POrotidine 5'-phosphate decarboxylase/0.441
3wycNAPMeso-diaminopimelate D-dehydrogenase1.4.1.160.441
4g3sUD1Bifunctional protein GlmU/0.441
4g74FADRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.441
4nt03DUOrotidine 5'-phosphate decarboxylase4.1.1.230.441
1c2tGARPhosphoribosylglycinamide formyltransferase/0.440
1e3eNAIAlcohol dehydrogenase 41.1.1.10.440
1juvNDPDihydrofolate reductase1.5.1.30.440
1pvgANPDNA topoisomerase 25.99.1.30.440
1tj0FADBifunctional protein PutA1.5.5.20.440
1vsoAT1Glutamate receptor ionotropic, kainate 1/0.440
2ad5ADPCTP synthase/0.440
2bd0NAPSepiapterin reductase/0.440
2c6lDT4Cyclin-dependent kinase 22.7.11.220.440
2gr1FADFerredoxin reductase/0.440
2itqITQEpidermal growth factor receptor2.7.10.10.440
2jdsL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.440
2vn0TDZCytochrome P450 2C8/0.440
2wbaFADTrypanothione reductase1.8.1.120.440
2xw7NDPDihydrofolate reductase/0.440
2y0mACOHistone acetyltransferase KAT8/0.440
2yj4ATPCopper-transporting ATPase/0.440
2zjwREFCasein kinase II subunit alpha2.7.11.10.440
3br3ETHTH-type transcriptional regulator QacR/0.440
3d2mCOAAmino-acid acetyltransferase/0.440
3gwfFADCyclohexanone monooxygenase/0.440
3k4nFADPyranose 2-oxidase/0.440
3kmeINNDisintegrin and metalloproteinase domain-containing protein 173.4.24.860.440
3mjeNDPAmphB/0.440
3n83ADPAldehyde dehydrogenase, mitochondrial1.2.1.30.440
3n8nN883-dehydroquinate dehydratase4.2.1.100.440
3oibFDAPutative acyl-CoA dehydrogenase/0.440
3ojxNAPNADPH--cytochrome P450 reductase/0.440
3q44D50M1 family aminopeptidase3.4.110.440
3zcnATPAdenosine monophosphate-protein transferase SoFic2.7.7.n10.440
4bwxAGSPAB-dependent poly(A)-specific ribonuclease subunit pan3/0.440
4dnaFADProbable glutathione reductase/0.440
4hgs15GCasein kinase I isoform gamma-32.7.11.10.440
4ho6UTPGlucose-1-phosphate thymidylyltransferase/0.440
4iteTEYVitamin D3 receptor/0.440
4m2aUPGUDP-glucose pyrophosphorylase/0.440