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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4xvq GNP GTPase HRas

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4xvq GNPGTPase HRas / 1.140
4dlz GNPGTPase HRas / 1.058
3oes GNPGTPase RhebL1 / 1.057
3mjh GTPRas-related protein Rab-5A / 1.051
3kko GNPRas-related protein M-Ras / 1.044
1zc3 GNPRas-related protein Ral-A / 1.042
2rgc GNPGTPase HRas / 1.042
4dlx GNPGTPase HRas / 1.041
1zc4 GNPRas-related protein Ral-A / 1.040
4lhw GNPRas-related protein Rab-8A / 1.039
1n6l GTPRas-related protein Rab-5A / 1.036
4dso GSPGTPase KRas / 1.034
3tgp GNPGTPase HRas / 1.031
1vg8 GNPRas-related protein Rab-7a / 1.030
4xvr GNPGTPase HRas / 1.029
4g0n GNPGTPase HRas / 1.020
3bc1 GNPRas-related protein Rab-27A / 1.015
3ddc GNPGTPase HRas / 1.013
2rgg GNPGTPase HRas / 1.012
3k9l GNPGTPase HRas / 1.012
2rge GNPGTPase HRas / 1.011
3i3s GNPGTPase HRas / 1.011
3oiu GNPGTPase HRas / 1.011
4dlv GNPGTPase HRas / 1.011
3k8y GNPGTPase HRas / 1.010
3l8y GNPGTPase HRas / 1.010
3oiw GNPGTPase HRas / 1.010
3rs0 GNPGTPase HRas / 1.010
3rsl GNPGTPase HRas / 1.010
3v4f GNPGTPase HRas / 1.010
4dlt GNPGTPase HRas / 1.010
3lbh GNPGTPase HRas / 1.009
3oiv GNPGTPase HRas / 1.009
3rs5 GNPGTPase HRas / 1.009
3rs7 GNPGTPase HRas / 1.009
4dlw GNPGTPase HRas / 1.009
3lbi GNPGTPase HRas / 1.008
3lbn GNPGTPase HRas / 1.008
3rs4 GNPGTPase HRas / 1.008
4l9w GNPGTPase HRas / 1.008
5b2z GNPGTPase HRas / 1.008
4dls GNPGTPase HRas / 1.007
1yu9 GNPRas-related protein Rab-4A / 1.006
4hdo GNPRas-related protein Rap-1b / 1.005
1g17 GNPRas-related protein SEC4 / 1.004
2bme GNPRas-related protein Rab-4A / 1.003
1yzq GNPRas-related protein Rab-6A / 1.002
4nyj GNPGTPase HRas / 0.997
1tu3 GNPRas-related protein Rab-5A / 0.995
3tso GNPRas-related protein Rab-25 / 0.994
4k81 GTPGTPase HRas / 0.994
4hdq GNPRas-related protein Rap-1b / 0.993
4kvg GTPRas-related protein Rap-1A / 0.993
2rgb GNPGTPase HRas / 0.992
3pit GNPRas-related protein M-Ras / 0.992
1uad GNPRas-related protein Ral-A / 0.991
3x1z GNPRas-related protein Rap-1b / 0.991
4nyi GNPGTPase HRas / 0.991
2c5l GTPGTPase HRas / 0.988
3rab GNPRas-related protein Rab-3A / 0.986
1gwn GTPRho-related GTP-binding protein RhoE / 0.984
1t91 GTPRas-related protein Rab-7a / 0.984
4dsn GCPGTPase KRas / 0.983
3qbt GNPRas-related protein Rab-8A / 0.979
1mh1 GNPRas-related C3 botulinum toxin substrate 1 / 0.978
2gil GTPRas-related protein Rab-6A / 0.978
3e5h GNPRas-related protein Rab-28 / 0.977
3a58 GNPGTP-binding protein RHO1 / 0.971
3sbd GNPRas-related C3 botulinum toxin substrate 1 / 0.971
4dvg GSPRho family GTPase / 0.968
2ffq GSPRas-related protein Rab-6B / 0.966
2cl6 CAGGTPase HRas / 0.964
4rkf GNPRas-related protein Rab-3 / 0.961
4js0 GNPCell division control protein 42 homolog / 0.960
3tnf GNPRas-related protein Rab-8A / 0.958
3th5 GNPRas-related C3 botulinum toxin substrate 1 / 0.957
2gcp GSPRho-related GTP-binding protein RhoC / 0.955
2ov2 GCPRas-related C3 botulinum toxin substrate 3 / 0.955
2qme GCPRas-related C3 botulinum toxin substrate 3 / 0.955
1ky2 GNPGTP-binding protein YPT7 / 0.951
1kmq GNPTransforming protein RhoA / 0.943
4qxa GTPRas-related protein Rab-9A / 0.943
1lfd GNPGTPase HRas / 0.941
4cym GCPRas-related protein Rab-32 / 0.941
1cxz GSPTransforming protein RhoA / 0.940
4dsu GDPGTPase KRas / 0.940
4wa7 GDPGTPase KRas / 0.940
2ce2 GDPGTPase HRas / 0.939
4xoi GTPTransforming protein RhoA / 0.937
4gzl GNPRas-related C3 botulinum toxin substrate 1 / 0.936
3cx8 GSPGuanine nucleotide-binding protein subunit alpha-13 / 0.927
3kud GDPGTPase HRas / 0.927
4tq9 GDPGTPase KRas / 0.926
3tkl GTPRas-related protein Rab-1A / 0.922
3x1w GDPRas-related protein Rap-1b / 0.922
4epx GDPGTPase KRas / 0.922
2fg5 GNPRas-related protein Rab-31 / 0.920
3sbe GNPRas-related C3 botulinum toxin substrate 1 / 0.920
4mit GTPRho-related protein racC / 0.918
1z2c GNPRho-related GTP-binding protein RhoC / 0.917
5c46 GSPRas-related protein Rab-11A / 0.917
4o2l GTPGTP-binding protein Rheb / 0.916
1a2b GSPTransforming protein RhoA / 0.914
1x1r GDPRas-related protein M-Ras / 0.914
4lhv GDPRas-related protein Rab-8A / 0.913
4ql3 GDPGTPase KRas / 0.913
1oix GDPRas-related protein Rab-11A / 0.912
1z0d GDPRas-related protein Rab-5C / 0.912
4q03 GDPGTPase KRas / 0.912
1m7b GTPRho-related GTP-binding protein RhoE / 0.911
2fe4 GDPRas-related protein Rab-6B / 0.911
3kuc GDPRas-related protein Rap-1A / 0.910
4dxa GSPRas-related protein Rap-1b / 0.909
4goj GNPADP-ribosylation factor-like protein 3 / 0.908
4q02 GDPGTPase KRas / 0.906
4l9s GDPGTPase HRas / 0.900
1e96 GTPRas-related C3 botulinum toxin substrate 1 / 0.897
3law GNPRas-related protein Rab-7a / 0.896
5dif GNPGTP-binding nuclear protein Ran / 0.894
4epw GDPGTPase KRas / 0.893
3b1x GNPFerrous iron transport protein B / 0.891
3kkq GDPRas-related protein M-Ras / 0.889
1zbd GTPRas-related protein Rab-3A / 0.887
4lv6 GDPGTPase KRas / 0.886
4uj3 GNPRas-related protein Rab-11A / 0.886
4d0l GSPRas-related protein Rab-11A / 0.883
1z0a GDPRas-related protein Rab-2A / 0.882
4xsg GSPTransforming protein RhoA / 0.881
4ldj GDPGTPase KRas / 0.879
4obe GDPGTPase KRas / 0.878
1s1c GNPTransforming protein RhoA / 0.875
4o2r GDPGTP-binding protein Rheb / 0.875
3ftq GNPSeptin-2 / 0.874
2dpx GDPGTP-binding protein RAD / 0.872
4l8g GDPGTPase KRas / 0.866
1gia GSPGuanine nucleotide-binding protein G(i) subunit alpha-1 / 0.863
2ic5 GDPRas-related C3 botulinum toxin substrate 3 / 0.863
4pao GSPGuanine nucleotide-binding protein G(i) subunit alpha-1 / 0.863
1cul GSPGuanine nucleotide-binding protein G(s) subunit alpha isoforms short / 0.862
3ref GDPRho family GTPase / 0.860
4idn GNPAtlastin-1 3.6.5 0.859
4lpk GDPGTPase KRas / 0.856
2j0s ANPEukaryotic initiation factor 4A-III 3.6.4.13 0.855
1d5c GDPGTPase (Rab6) / 0.852
2q3f GNPRas-related GTP-binding protein D / 0.852
5di3 GNPADP-ribosylation factor-like protein 3 / 0.851
3kz1 GSPTransforming protein RhoA / 0.849
4o25 GTPGTP-binding protein Rheb / 0.848
2p2l GDPRas-related C3 botulinum toxin substrate 1 / 0.846
5jlj GNPGTP-binding nuclear protein Ran / 0.846
1wdt GTPElongation factor G (EF-G-2) / 0.842
2ic5 GNPRas-related C3 botulinum toxin substrate 3 / 0.842
2xtz GSPGuanine nucleotide-binding protein alpha-1 subunit / 0.841
1ow3 GDPTransforming protein RhoA / 0.840
4itr GDPCell division control protein 42 homolog / 0.839
4lrw GDPGTPase KRas / 0.837
1g16 GDPRas-related protein SEC4 / 0.836
2fju GSPRas-related C3 botulinum toxin substrate 1 / 0.836
1xtr GNPGTP-binding protein Rheb / 0.835
3w3z GTPGTP-binding nuclear protein Ran / 0.835
2qtv GNPSmall COPII coat GTPase SAR1 3.6.5 0.834
4uj5 GNPRas-related protein Rab-11A / 0.834
1cs4 GSPGuanine nucleotide-binding protein G(s) subunit alpha isoforms short / 0.831
5dha GNPGTP-binding nuclear protein Ran / 0.831
1z0f GDPRas-related protein Rab-14 / 0.829
3myk ANPMyosin-2 heavy chain / 0.829
3wyg GTPGTP-binding nuclear protein GSP1/CNR1 / 0.829
2bku GTPGTP-binding nuclear protein Ran / 0.828
2j0v GDPRac-like GTP-binding protein ARAC7 / 0.827
3cph GDPRas-related protein SEC4 / 0.825
4tl7 ATPCircadian clock protein kinase KaiC 2.7.11.1 0.817
5l3s GNPSignal recognition particle receptor FtsY / 0.814
2g0n GDPRas-related C3 botulinum toxin substrate 3 / 0.813
4jsy GTPMetallophosphoesterase / 0.812
3vx4 ATPPutative ABC transporter, ATP-binding protein ComA / 0.811
3ea5 GDPGTP-binding nuclear protein Ran / 0.810
1wa5 GTPGTP-binding nuclear protein Ran / 0.808
2bc9 GNPGuanylate-binding protein 1 / 0.808
2cls GTPRho-related GTP-binding protein Rho6 / 0.808
2gvd GSPGuanine nucleotide-binding protein G(s) subunit alpha isoforms short / 0.808
3dt4 GTPPhosphoenolpyruvate carboxykinase, cytosolic [GTP] 4.1.1.32 0.808
1ibr GNPGTP-binding nuclear protein Ran / 0.807
2jj2 ANPATP synthase subunit beta, mitochondrial 3.6.3.14 0.807
1gil GSPGuanine nucleotide-binding protein G(i) subunit alpha-1 / 0.805
2j5x GSPADP-ribosylation factor 6 / 0.805
2w2x GSPRas-related C3 botulinum toxin substrate 2 / 0.805
3r9x GNPGTPase Era / 0.805
1yra GDPGPN-loop GTPase PAB0955 / 0.801
1mmg AGSMyosin-2 heavy chain / 0.800
4ylg GDPADP-ribosylation factor 1, putative / 0.800
1w5t ANPORC1-type DNA replication protein 2 / 0.796
4y0v GDPADP-ribosylation factor 1, putative / 0.795
4db1 ANPMyosin-7 / 0.794
1f5n GNPGuanylate-binding protein 1 / 0.793
3adc ANPL-seryl-tRNA(Sec) kinase 2.7.1.164 0.793
4m0l GDPTranslation initiation factor 2 subunit gamma / 0.793
4r43 GDPPhosphoenolpyruvate carboxykinase [GTP] / 0.793
3tjz GNPADP-ribosylation factor 1 / 0.792
2j7p GNPSignal recognition particle protein / 0.790
2j7p GNPSignal recognition particle receptor FtsY / 0.790
4xvu ATPATPase GET3 / 0.789
2fna ADPUncharacterized protein / 0.787
1zd9 GDPADP-ribosylation factor-like protein 8A / 0.784
2jlr ANPGenome polyprotein 3.4.21.91 0.784
3vhx GTPADP-ribosylation factor 6 / 0.784
1azt GSPGuanine nucleotide-binding protein G(s) subunit alpha isoforms short / 0.783
1am4 GNPCell division control protein 42 homolog / 0.782
3a4l ANPL-seryl-tRNA(Sec) kinase 2.7.1.164 0.782
5l3r GCPCell division protein FtsY homolog, chloroplastic / 0.781
3fwy ADPLight-independent protochlorophyllide reductase iron-sulfur ATP-binding protein / 0.779
4xjx ATPType I restriction enzyme EcoR124II R protein 3.1.21.3 0.779
5k5z ANPUncharacterized protein / 0.779
3wyf GTPGTP-binding nuclear protein / 0.776
1xts GTPGTP-binding protein Rheb / 0.774
2jiz ANPATP synthase subunit beta, mitochondrial 3.6.3.14 0.774
3zia ATPATP synthase subunit alpha, mitochondrial / 0.774
4tlb AGSCircadian clock protein kinase KaiC 2.7.11.1 0.774
4tlc AGSCircadian clock protein kinase KaiC 2.7.11.1 0.774
4tle AGSCircadian clock protein kinase KaiC 2.7.11.1 0.774
4yqf GDPSeptin-9 / 0.774
4tld AGSCircadian clock protein kinase KaiC 2.7.11.1 0.773
4luc GDPGTPase KRas / 0.771
3eg5 GNPCell division control protein 42 homolog / 0.770
5aun ADPIron-sulfur cluster carrier protein / 0.770
1z2a GDPRas-related protein Rab-23 / 0.769
2ck3 ANPATP synthase subunit alpha, mitochondrial / 0.768
2ck3 ANPATP synthase subunit beta, mitochondrial 3.6.3.14 0.768
4pjk ADPMyosin-2 heavy chain / 0.768
4idp GNPAtlastin-1 3.6.5 0.767
1jx2 ADPMyosin-2 heavy chain / 0.766
3bbp GTPRas-related protein Rab-6A / 0.765
4z54 GDPNeuronal-specific septin-3 / 0.765
1h65 GDPTranslocase of chloroplast 34 3.6.5 0.764
5bn3 ADPV-type ATP synthase alpha chain / 0.763
5bn3 ADPNEQ263 / 0.763
2bif ANP6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 2.7.1.105 0.761
2l0x GDPGTP-binding protein Rheb / 0.761
3bb3 GDPTranslocase of chloroplast 33, chloroplastic 3.6.5 0.761
4cid ANPEH domain-containing protein 2 / 0.761
2pg2 ADPKinesin-like protein KIF11 / 0.759
3hu3 AGSTransitional endoplasmic reticulum ATPase 3.6.4.6 0.759
1rj9 GCPSignal recognition particle receptor FtsY / 0.758
2x2r ADPKinesin-like protein KIF11 / 0.757
2xtn GTPGTPase IMAP family member 2 / 0.756
3hu1 AGSTransitional endoplasmic reticulum ATPase 3.6.4.6 0.756
4tl9 AGSCircadian clock protein kinase KaiC 2.7.11.1 0.756
2zfi ADPKinesin-like protein KIF1A / 0.755
1okk GCPSignal recognition particle protein / 0.754
1okk GCPSignal recognition particle receptor FtsY / 0.754
4asu ADPATP synthase subunit alpha, mitochondrial / 0.754
1bof GDPGuanine nucleotide-binding protein G(i) subunit alpha-1 / 0.753
1ytm ATPPhosphoenolpyruvate carboxykinase (ATP) / 0.753
2gm1 ADPKinesin-like protein KIF11 / 0.753
2hf8 GSPProbable hydrogenase nickel incorporation protein HypB / 0.753
2qen ADPWalker-Type ATPase / 0.752
2jiz ADPATP synthase subunit beta, mitochondrial 3.6.3.14 0.751
3cob ADPKinesin heavy chain-like protein / 0.751
4cvm ANPUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase / 0.751
4ko8 AGSTransitional endoplasmic reticulum ATPase 3.6.4.6 0.751
4ncl GDPEukaryotic translation initiation factor 5B / 0.751
1m2o GNPSmall COPII coat GTPase SAR1 3.6.5 0.750
1mma ADPMyosin-2 heavy chain / 0.750
4v02 ATPSite-determining protein / 0.750
4oi4 ATPmRNA cleavage and polyadenylation factor CLP1 / 0.749
1e79 ADPATP synthase subunit alpha, mitochondrial / 0.748
1e79 ADPATP synthase subunit beta, mitochondrial 3.6.3.14 0.748
1fnn ADPORC1-type DNA replication protein / 0.748
1khb GCPPhosphoenolpyruvate carboxykinase, cytosolic [GTP] 4.1.1.32 0.748
2v7q ATPATP synthase subunit alpha, mitochondrial / 0.748
2v7q ATPATP synthase subunit beta, mitochondrial 3.6.3.14 0.748
3onw GDPGuanine nucleotide-binding protein G(i) subunit alpha-1 / 0.748
4g01 GDPRas-related protein RABF2b / 0.748
1v8k ANPKinesin-like protein KIF2C / 0.747
2zts ADPUncharacterized protein / 0.747
2y65 ADPKinesin heavy chain / 0.746
1gp2 GDPGuanine nucleotide-binding protein G(i) subunit alpha-1 / 0.745
4ol0 GTPGTP-binding nuclear protein Ran / 0.745
1ayl ATPPhosphoenolpyruvate carboxykinase (ATP) / 0.744
5cyo GDPSeptin-9 / 0.744
1esn ANPPantothenate kinase 2.7.1.33 0.743
1p3d ANPUDP-N-acetylmuramate--L-alanine ligase 6.3.2.8 0.743
3ews ADPATP-dependent RNA helicase DDX19B 3.6.4.13 0.743
4g5q GDPGuanine nucleotide-binding protein G(i) subunit alpha-1 / 0.743
1ank ANPAdenylate kinase / 0.742
1w1w AGSStructural maintenance of chromosomes protein 1 / 0.742
3t1t GDPProbable gliding protein mglA / 0.742
3c15 GSPGuanine nucleotide-binding protein G(s) subunit alpha isoforms short / 0.741
4a28 ADPKinesin-like protein KIF11 / 0.741
3sqw ANPATP-dependent RNA helicase MSS116, mitochondrial 3.6.4.13 0.740
1u0h GSPGuanine nucleotide-binding protein G(s) subunit alpha isoforms short / 0.739
1w0k ADPATP synthase subunit alpha, mitochondrial / 0.739
1w0k ADPATP synthase subunit beta, mitochondrial 3.6.3.14 0.739
2v7q ADPATP synthase subunit beta, mitochondrial 3.6.3.14 0.739
4cei ANPATP-dependent helicase/deoxyribonuclease subunit B 3.1 0.739
4wou GDPPhosphoenolpyruvate carboxykinase [GTP] / 0.739
5d3q GDPDynamin-1 3.6.5.5 0.739
2msc GDPMHC class I alpha chain / 0.738
3m0e ATPTranscriptional regulator (NtrC family) / 0.738
3oee ANPATP synthase subunit alpha, mitochondrial / 0.738
3oee ANPATP synthase subunit beta, mitochondrial 3.6.3.14 0.738
4gzm GSPRas-related C3 botulinum toxin substrate 1 / 0.738
5i67 GDPPhosphoenolpyruvate carboxykinase [GTP] / 0.738
1l8q ADPChromosomal replication initiator protein DnaA / 0.737
2r9v ATPATP synthase subunit alpha / 0.737
3r9i ADPSeptum site-determining protein MinD / 0.737
3zvm ADPBifunctional polynucleotide phosphatase/kinase 2.7.1.78 0.737
4pfp ADPUnconventional myosin-VI / 0.737
4ymu ATPABC-type polar amino acid transport system, ATPase component / 0.737
1q3h ANPCystic fibrosis transmembrane conductance regulator / 0.736
1xms ANPProtein RecA / 0.736
2jj2 ADPATP synthase subunit alpha, mitochondrial / 0.736
2jj2 ADPATP synthase subunit beta, mitochondrial 3.6.3.14 0.736
2xae ADPKinesin-like protein KIF11 / 0.736
4ki0 ANPMaltose/maltodextrin import ATP-binding protein MalK / 0.736
3k3b ADPKinesin-like protein KIF11 / 0.735
4gp6 ADPMetallophosphoesterase / 0.735
4pan GDPGuanine nucleotide-binding protein G(i) subunit alpha-1 / 0.735
1ii6 ADPKinesin-like protein KIF11 / 0.734
1p9w ANPType II secretion system protein E / 0.733
3c16 GSPGuanine nucleotide-binding protein G(s) subunit alpha isoforms short / 0.733
4bzq ADPBifunctional enzyme CysN/CysC 2.7.1.25 0.733
4dzz ADPPlasmid partitioning protein ParF / 0.733
1bmf ANPATP synthase subunit alpha, mitochondrial / 0.732
1bmf ANPATP synthase subunit beta, mitochondrial 3.6.3.14 0.732
1z6t ADPApoptotic protease-activating factor 1 / 0.732
3tqc ADPPantothenate kinase / 0.731
4qos ADPPsp operon transcriptional activator / 0.731
4tla ADPCircadian clock protein kinase KaiC 2.7.11.1 0.731
1in5 ADPHolliday junction ATP-dependent DNA helicase RuvB / 0.729
2uyi ADPKinesin-like protein KIF11 / 0.729
3cx6 GDPGuanine nucleotide-binding protein subunit alpha-13 / 0.729
3fkq ATPNtrC-like two-domain protein / 0.729
3q9l ATPSeptum site-determining protein MinD / 0.729
1bmf ADPATP synthase subunit alpha, mitochondrial / 0.728
1bmf ADPATP synthase subunit beta, mitochondrial 3.6.3.14 0.728
2db3 ANPATP-dependent RNA helicase vasa, isoform A 3.6.4.13 0.728
2w2v GTPRas-related C3 botulinum toxin substrate 2 / 0.728
2x7e ADPKinesin-like protein KIF11 / 0.728
1yrs ADPKinesin-like protein KIF11 / 0.726
1got GDPGuanine nucleotide-binding protein G(t) subunit alpha-1 / 0.725
1w5t ADPORC1-type DNA replication protein 2 / 0.725
1zcb GDPGuanine nucleotide-binding protein subunit alpha-13 / 0.725
3hqd ANPKinesin-like protein KIF11 / 0.725
3l9h ADPKinesin-like protein KIF11 / 0.725
1sdm ADPKinesin heavy chain-like protein / 0.724
3oeh ANPATP synthase subunit alpha, mitochondrial / 0.724
2hld ANPATP synthase subunit alpha, mitochondrial / 0.723
2hld ANPATP synthase subunit beta, mitochondrial 3.6.3.14 0.723
4ap0 ADPKinesin-like protein KIF11 / 0.722
4b7b ADPKinesin-like protein KIF11 / 0.722
4jl6 ADPAdenylate kinase / 0.722
4jlo ADPAdenylate kinase / 0.722
2gks ADPProbable bifunctional SAT/APS kinase 2.7.1.25 0.720
1i4l GDPRas-related C3 botulinum toxin substrate 1 / 0.719
3hu2 AGSTransitional endoplasmic reticulum ATPase 3.6.4.6 0.719
4hse ADPChaperone protein ClpB / 0.719
4jld ADPAdenylate kinase / 0.719
2dwp ACP6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 2.7.1.105 0.718
3moh GDPPhosphoenolpyruvate carboxykinase, cytosolic [GTP] 4.1.1.32 0.718
1khe GCPPhosphoenolpyruvate carboxykinase, cytosolic [GTP] 4.1.1.32 0.717
2qf2 GDPPhosphoenolpyruvate carboxykinase, cytosolic [GTP] 4.1.1.32 0.717
3kji ADPCO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC / 0.717
4cf7 ADPAdenylate kinase / 0.716
4hi0 GDPUrease accessory protein UreG / 0.716
1w5s ADPORC1-type DNA replication protein 2 / 0.715
1xnj ADPBifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 2.7.1.25 0.715
5irn ADPNucleotide binding oligomerization domain containing 2 / 0.715
1e1q ADPATP synthase subunit beta, mitochondrial 3.6.3.14 0.714
1sq5 ADPPantothenate kinase 2.7.1.33 0.714
3c41 ANPAmino acid ABC transporter / 0.714
3k1j ADPATP-dependent protease Lon / 0.714
1rrg GDPADP-ribosylation factor 1 / 0.713
1wbb ADPDNA mismatch repair protein MutS / 0.713
3d8b ADPFidgetin-like protein 1 3.6.4 0.713
4a1z ADPKinesin-like protein KIF11 / 0.713
4d81 ADPAAA ATPase, central domain protein / 0.713
1a4r GNHCell division control protein 42 homolog / 0.712
3a6p GTPGTP-binding nuclear protein Ran / 0.712
3bos CDPRegulatory inactivation of DnaA Hda protein / 0.712
4pjj ADPUnconventional myosin-VI / 0.712
3ieu GDPGTPase Era / 0.711
3sqx ANPATP-dependent RNA helicase MSS116, mitochondrial 3.6.4.13 0.711
4zca ADPKinesin-like protein KIF11 / 0.711
1svw GTPProbable GTP-binding protein EngB / 0.710
2c9o ADPRuvB-like 1 3.6.4.12 0.710
3qe0 GDPGuanine nucleotide-binding protein G(i) subunit alpha-1 / 0.710
3qpv ADP6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 2.7.1.105 0.710
4pk4 ADPUnconventional myosin-VI / 0.710
3ea0 ATPATPase, ParA family / 0.709
3ums GDPGuanine nucleotide-binding protein G(i) subunit alpha-1 / 0.709
4ohv ANPProtein clpf-1 / 0.709
1bif AGS6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 2.7.1.105 0.708
3q5d GDPAtlastin-1 3.6.5 0.706
1nly AGSCag alpha / 0.705
2eck ADPAdenylate kinase / 0.705
1k5d GNPGTP-binding nuclear protein Ran / 0.703
5hpy GDPTransforming protein RhoA / 0.703
1b7t ADPMyosin heavy chain, striated muscle / 0.702
1ny5 ADPTranscriptional regulator (NtrC family) / 0.702
3i5x ANPATP-dependent RNA helicase MSS116, mitochondrial 3.6.4.13 0.702
3tlx ADPAdenylate kinase 2 / 0.702
1w7k ADPDihydrofolate synthase/folylpolyglutamate synthase 6.3.2.12 0.699
4ike ADPAdenylate kinase / 0.699
1h8h ADPATP synthase subunit alpha, mitochondrial / 0.698
1h8h ADPATP synthase subunit beta, mitochondrial 3.6.3.14 0.698
1ohh ANPATP synthase subunit alpha, mitochondrial / 0.698
1ohh ANPATP synthase subunit beta, mitochondrial 3.6.3.14 0.698
2jj1 ADPATP synthase subunit alpha, mitochondrial / 0.698
2jj1 ADPATP synthase subunit beta, mitochondrial 3.6.3.14 0.698
3c14 GSPGuanine nucleotide-binding protein G(s) subunit alpha isoforms short / 0.697
3l1c ADPProtein claret segregational / 0.697
2vf7 ADPUvrABC system protein A / 0.696
2jj1 ANPATP synthase subunit alpha, mitochondrial / 0.695
4jjz ADPFormate--tetrahydrofolate ligase / 0.695
1fmw ATPMyosin-2 heavy chain / 0.694
1mez GDPAdenylosuccinate synthetase isozyme 1 / 0.694
2iut AGSDNA translocase FtsK / 0.694
2zrj AGSProtein RecA / 0.694
3zia ADPATP synthase subunit beta, mitochondrial 3.6.3.14 0.694
4jky ADPAdenylate kinase / 0.693
4bec ATPType I restriction enzyme EcoR124II R protein 3.1.21.3 0.692
3tif ADPUncharacterized ABC transporter ATP-binding protein MJ0796 / 0.691
2fl2 ADPKinesin-like protein KIF11 / 0.690
4c0b ATPmRNA cleavage and polyadenylation factor CLP1 / 0.690
4ys0 ADPProtein translocase subunit SecA / 0.690
3qcz ANPDihydrofolate synthase/folylpolyglutamate synthase / 0.689
4ag5 ADPType IV secretory pathway VirB4 components-like protein / 0.689
4iok ADPFormate--tetrahydrofolate ligase / 0.689
1xef ATPAlpha-hemolysin translocation ATP-binding protein HlyB / 0.688
2bbw GP5Adenylate kinase 4, mitochondrial / 0.688
4c30 ANPDNA helicase / 0.688
2whx ADPGenome polyprotein 3.4.21.91 0.685
3pfi ADPHolliday junction ATP-dependent DNA helicase RuvB / 0.684
4oi2 ADPProtein clpf-1 / 0.684
1g6o ADPCag alpha / 0.682
1ofh ADPATP-dependent protease ATPase subunit HslU / 0.682
2r6g ATPMaltose/maltodextrin import ATP-binding protein MalK / 0.682
2zr9 DTPProtein RecA / 0.682
1nsf ATPVesicle-fusing ATPase 3.6.4.6 0.681
2v1x ADPATP-dependent DNA helicase Q1 3.6.4.12 0.681
2xsz ATPRuvB-like 2 3.6.4.12 0.681
4r9u ANPVitamin B12 import ATP-binding protein BtuD / 0.681
1svl ADPLarge T antigen 3.6.4 0.680
3qbv GDPCell division control protein 42 homolog / 0.680
3nbz GTPGTP-binding nuclear protein Ran / 0.679
1oyy AGSATP-dependent DNA helicase RecQ 3.6.4.12 0.678
4ww0 ADPATP-dependent zinc metalloprotease FtsH / 0.678
2jcs TTPDeoxynucleoside kinase / 0.677
3mle ADPATP-dependent dethiobiotin synthetase BioD 6.3.3.3 0.677
3nbx ADPATPase RavA 3.6.3 0.677
4ohx ADPProtein clpf-1 / 0.677
1aq2 ATPPhosphoenolpyruvate carboxykinase (ATP) / 0.676
2g1q ADPKinesin-like protein KIF11 / 0.676
2zet GTPRas-related protein Rab-27B / 0.674
2d4h 5GPGuanylate-binding protein 1 / 0.673
4kln AGSTransitional endoplasmic reticulum ATPase 3.6.4.6 0.673
4a51 ADPKinesin-like protein KIF11 / 0.672
4be7 ATPType I restriction enzyme EcoR124II R protein 3.1.21.3 0.672
4zir ANPEnergy-coupling factor transporter ATP-binding protein EcfA2 3.6.3 0.672
4zir ANPEnergy-coupling factor transporter ATP-binding protein EcfA1 / 0.672
1k6m AGS6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 2.7.1.105 0.671
1svm ATPLarge T antigen 3.6.4 0.671
1w7i ADPUnconventional myosin-Va / 0.671
2c96 ATPPsp operon transcriptional activator / 0.671
2zro ADPProtein RecA / 0.671
1e1q ANPATP synthase subunit alpha, mitochondrial / 0.670
1e1q ANPATP synthase subunit beta, mitochondrial 3.6.3.14 0.670
1xmv ADPProtein RecA / 0.670
2ce7 ADPATP-dependent zinc metalloprotease FtsH / 0.670
3zl8 ADPUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase / 0.670
4to0 DTPDeoxynucleoside triphosphate triphosphohydrolase SAMHD1 3.1.5 0.670
1s3s ADPTransitional endoplasmic reticulum ATPase 3.6.4.6 0.669
3pcr GTPADP-ribosylation factor 6 / 0.668
4cvl ACPUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase / 0.668
1e0j ANPDNA primase/helicase 2.7.7 0.666
1um8 ADPATP-dependent Clp protease ATP-binding subunit ClpX / 0.666
2uz3 TTPThymidine kinase / 0.663
1ni4 TPPPyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial 1.2.4.1 0.662
1ni4 TPPPyruvate dehydrogenase E1 component subunit beta, mitochondrial 1.2.4.1 0.662
1im2 ADPATP-dependent protease ATPase subunit HslU / 0.661
2xau ADPPre-mRNA-splicing factor ATP-dependent RNA helicase PRP43 3.6.4.13 0.661
3qi2 GDPGuanine nucleotide-binding protein G(i) subunit alpha-1 / 0.659
4ma4 ADP6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 2.7.1.105 0.659
1dj2 GDPAdenylosuccinate synthetase, chloroplastic / 0.658
1ht2 ADPATP-dependent protease ATPase subunit HslU / 0.658
1r0z ATPCystic fibrosis transmembrane conductance regulator / 0.657
2zsa ADPPantothenate kinase 2.7.1.33 0.657
4kod ADPTransitional endoplasmic reticulum ATPase 3.6.4.6 0.657
4ww4 ADPRuvB-like helicase / 0.656
1fp6 ADPNitrogenase iron protein 1 1.18.6.1 0.655
2dft ADPShikimate kinase 2.7.1.71 0.655
1xbt TTPThymidine kinase, cytosolic 2.7.1.21 0.654
2ywv ADPPhosphoribosylaminoimidazole-succinocarboxamide synthase / 0.654
3uk6 ADPRuvB-like 2 3.6.4.12 0.654
1ake AP5Adenylate kinase / 0.653
2c98 ADPPsp operon transcriptional activator / 0.653
2zsb ADPPantothenate kinase 2.7.1.33 0.653
4qm6 GTPMetallophosphoesterase / 0.653
2dr3 ADPUPF0273 protein PH0284 / 0.652
2fgj ATPAlpha-hemolysin translocation ATP-binding protein HlyB / 0.652
4lja ACPChaperone protein ClpB / 0.652
2ad5 ADPCTP synthase / 0.651
4rz3 ADPSite-determining protein / 0.651
5ftf ADPTPR domain protein / 0.651
1gqy ACPUDP-N-acetylmuramate--L-alanine ligase 6.3.2.8 0.650