sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4nzh | FAD | L-ornithine N(5)-monooxygenase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 4nzh | FAD | L-ornithine N(5)-monooxygenase | / | 1.215 | |
| 4b69 | FAD | L-ornithine N(5)-monooxygenase | / | 1.142 | |
| 5cku | FAD | L-ornithine N(5)-monooxygenase | / | 1.119 | |
| 4b64 | FAD | L-ornithine N(5)-monooxygenase | / | 1.087 | |
| 4b63 | FAD | L-ornithine N(5)-monooxygenase | / | 0.998 | |
| 4b65 | FAD | L-ornithine N(5)-monooxygenase | / | 0.987 | |
| 4b68 | FAD | L-ornithine N(5)-monooxygenase | / | 0.984 | |
| 4b66 | FAD | L-ornithine N(5)-monooxygenase | / | 0.907 | |
| 4b67 | FAD | L-ornithine N(5)-monooxygenase | / | 0.880 | |
| 4tm3 | FAD | KtzI | / | 0.873 | |
| 2xvf | FAD | Putative flavin-containing monooxygenase | / | 0.849 | |
| 4tlx | FDA | KtzI | / | 0.827 | |
| 4tlz | FAD | KtzI | / | 0.807 | |
| 2gv8 | FAD | Thiol-specific monooxygenase | 1.14.13 | 0.805 | |
| 4gcm | FAD | Thioredoxin reductase | 1.8.1.9 | 0.799 | |
| 4icy | FAD | PgaE | / | 0.796 | |
| 3oz2 | FAD | Digeranylgeranylglycerophospholipid reductase | / | 0.795 | |
| 3ish | FAD | Thioredoxin reductase | 1.8.1.9 | 0.794 | |
| 3uox | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.790 | |
| 3ict | FAD | Coenzyme A disulfide reductase | / | 0.779 | |
| 4jq9 | FAD | Dihydrolipoyl dehydrogenase | / | 0.779 | |
| 1k0l | FAD | p-hydroxybenzoate hydroxylase | / | 0.778 | |
| 1k0j | FAD | p-hydroxybenzoate hydroxylase | / | 0.776 | |
| 3s5w | FAD | L-ornithine N(5)-monooxygenase | / | 0.776 | |
| 4jdr | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.776 | |
| 5buk | FAD | FADH2-dependent halogenase | / | 0.776 | |
| 4tm1 | FDA | KtzI | / | 0.775 | |
| 1d7l | RFL | p-hydroxybenzoate hydroxylase | / | 0.773 | |
| 2hqm | FAD | Glutathione reductase | 1.8.1.7 | 0.770 | |
| 1zk7 | FAD | Mercuric reductase | 1.16.1.1 | 0.769 | |
| 3cge | FAD | Coenzyme A disulfide reductase | / | 0.768 | |
| 3pl8 | FAD | Pyranose 2-oxidase | / | 0.768 | |
| 4x4j | FAD | Putative oxygenase | / | 0.767 | |
| 2fje | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.766 | |
| 2q7v | FAD | Thioredoxin reductase | / | 0.766 | |
| 3cgc | FAD | Coenzyme A disulfide reductase | / | 0.760 | |
| 3cgd | FAD | Coenzyme A disulfide reductase | / | 0.760 | |
| 4gut | FAD | Lysine-specific histone demethylase 1B | 1 | 0.759 | |
| 5eow | FAD | 6-hydroxynicotinate 3-monooxygenase | 1.14.13.114 | 0.759 | |
| 1pdh | FAS | p-hydroxybenzoate hydroxylase | / | 0.756 | |
| 3oc4 | FAD | Oxidoreductase, pyridine nucleotide-disulfide family | / | 0.756 | |
| 4k2x | FAD | Polyketide oxygenase/hydroxylase | / | 0.756 | |
| 3g5s | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.754 | |
| 3nlc | FAD | Uncharacterized protein | / | 0.754 | |
| 4tm4 | FDA | KtzI | / | 0.754 | |
| 3f8d | FAD | NADH oxidase/thioredoxin reductase | / | 0.753 | |
| 4tm0 | FAD | KtzI | / | 0.752 | |
| 3k7m | FAD | 6-hydroxy-L-nicotine oxidase | / | 0.751 | |
| 4j2w | FAD | Kynurenine 3-monooxygenase | / | 0.751 | |
| 3grs | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.750 | |
| 4cnk | FAD | L-amino acid oxidase | / | 0.750 | |
| 3djg | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.749 | |
| 1gra | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.747 | |
| 1rp0 | AHZ | Thiamine thiazole synthase, chloroplastic | / | 0.747 | |
| 2qa1 | FAD | PgaE | / | 0.747 | |
| 4gr1 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.746 | |
| 5g3s | FDA | Flavin-dependent L-tryptophan oxidase VioA | / | 0.746 | |
| 3cgb | FAD | Coenzyme A disulfide reductase | / | 0.744 | |
| 3gyi | FAD | Cholesterol oxidase | 1.1.3.6 | 0.744 | |
| 3uoy | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.744 | |
| 2xve | FAD | Putative flavin-containing monooxygenase | / | 0.743 | |
| 5fs8 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.743 | |
| 5g3t | FDA | Flavin-dependent L-tryptophan oxidase VioA | / | 0.743 | |
| 2vq7 | FAD | Putative flavin-containing monooxygenase | / | 0.742 | |
| 3dk8 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.742 | |
| 4fwf | FAD | Lysine-specific histone demethylase 1B | 1 | 0.742 | |
| 1zx9 | FAD | Mercuric reductase | 1.16.1.1 | 0.740 | |
| 2ign | FAD | Pyranose 2-oxidase | / | 0.740 | |
| 3uov | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.740 | |
| 1gre | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.739 | |
| 1ryi | FAD | Glycine oxidase | 1.4.3.19 | 0.739 | |
| 2i0z | FAD | NAD(FAD)-utilizing dehydrogenases | / | 0.738 | |
| 3p9u | FAD | TetX family tetracycline inactivation enzyme | / | 0.737 | |
| 2jae | FAD | L-amino acid oxidase | / | 0.736 | |
| 1fl2 | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.735 | |
| 3klj | FAD | NADH-rubredoxin oxidoreductase | 1.18.1.1 | 0.735 | |
| 1get | FAD | Glutathione reductase | 1.8.1.7 | 0.732 | |
| 3nt6 | FAD | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.732 | |
| 3djj | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.731 | |
| 4rek | FAD | Cholesterol oxidase | 1.1.3.6 | 0.731 | |
| 1h83 | FAD | Polyamine oxidase | 1.5.3.14 | 0.730 | |
| 1ju2 | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.730 | |
| 2iw5 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.730 | |
| 4ech | FAD | Polyamine oxidase FMS1 | / | 0.730 | |
| 1b4v | FAD | Cholesterol oxidase | 1.1.3.6 | 0.729 | |
| 4k5r | FAD | Oxygenase | / | 0.729 | |
| 2c3c | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.728 | |
| 3b6d | FAE | Cholesterol oxidase | 1.1.3.6 | 0.728 | |
| 3icr | FAD | Coenzyme A disulfide reductase | / | 0.728 | |
| 3ntd | FAD | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.728 | |
| 3k4c | FAD | Pyranose 2-oxidase | / | 0.727 | |
| 4fwj | FAD | Lysine-specific histone demethylase 1B | 1 | 0.727 | |
| 2jb1 | FAD | L-amino acid oxidase | / | 0.726 | |
| 2jb2 | FAD | L-amino acid oxidase | / | 0.726 | |
| 2yr5 | FAD | Phenylalanine 2-monooxygenase precursor | 1.13.12.9 | 0.726 | |
| 3kve | FAD | L-amino-acid oxidase | / | 0.726 | |
| 1f8w | FAD | NADH peroxidase | 1.11.1.1 | 0.725 | |
| 1geu | FAD | Glutathione reductase | 1.8.1.7 | 0.725 | |
| 1rsg | FAD | Polyamine oxidase FMS1 | / | 0.725 | |
| 2q0l | FAD | Thioredoxin reductase | 1.8.1.9 | 0.725 | |
| 1cc2 | FAD | Cholesterol oxidase | 1.1.3.6 | 0.724 | |
| 1jnr | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.724 | |
| 1v59 | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.724 | |
| 3nta | FAD | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.724 | |
| 3sz0 | FAD | Sulfide-quinone reductase | / | 0.724 | |
| 1ijh | FAD | Cholesterol oxidase | 1.1.3.6 | 0.723 | |
| 2vou | FAD | 2,6-dihydroxypyridine 3-monooxygenase | 1.14.13.10 | 0.723 | |
| 3cnj | FAD | Cholesterol oxidase | 1.1.3.6 | 0.723 | |
| 4hb9 | FAD | Uncharacterized protein | / | 0.723 | |
| 2b9w | FAD | Putative aminooxidase | / | 0.722 | |
| 2yg6 | FAD | Putrescine oxidase | / | 0.722 | |
| 2b9x | FAD | Putative aminooxidase | / | 0.721 | |
| 3bg7 | FAD | Pyranose 2-oxidase | / | 0.721 | |
| 3syi | FAD | Sulfide-quinone reductase | / | 0.719 | |
| 2bra | FAD | [F-actin]-methionine sulfoxide oxidase MICAL1 | 1.14.13 | 0.718 | |
| 4fwe | FAD | Lysine-specific histone demethylase 1B | 1 | 0.718 | |
| 1b8s | FAD | Cholesterol oxidase | 1.1.3.6 | 0.717 | |
| 2xlp | FAD | Putative flavin-containing monooxygenase | / | 0.717 | |
| 2yg3 | FAD | Putrescine oxidase | / | 0.717 | |
| 2gh5 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.716 | |
| 3r9u | FAD | Thioredoxin reductase | / | 0.716 | |
| 3rha | FDA | Putrescine oxidase | / | 0.716 | |
| 3t37 | FAD | Pyridoxine 4-oxidase | / | 0.716 | |
| 1n4v | FAD | Cholesterol oxidase | 1.1.3.6 | 0.715 | |
| 3duw | SAH | O-methyltransferase, putative | / | 0.715 | |
| 4a99 | FAD | TetX family tetracycline inactivation enzyme | / | 0.715 | |
| 4u2s | FDA | Cholesterol oxidase | 1.1.3.6 | 0.715 | |
| 4udq | FAD | 5-(hydroxymethyl)furfural oxidase | / | 0.715 | |
| 5eb5 | FAD | (R)-mandelonitrile lyase 1 | 4.1.2.10 | 0.715 | |
| 1gsn | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.714 | |
| 1nhq | FAD | NADH peroxidase | 1.11.1.1 | 0.714 | |
| 1dnc | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.713 | |
| 1ges | FAD | Glutathione reductase | 1.8.1.7 | 0.713 | |
| 3l8k | ADP | Dihydrolipoamide dehydrogenase (PdhD-3) | / | 0.713 | |
| 4eqr | FAD | Coenzyme A disulfide reductase | / | 0.712 | |
| 1nhs | FAD | NADH peroxidase | 1.11.1.1 | 0.711 | |
| 1grb | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.710 | |
| 1nhr | FAD | NADH peroxidase | 1.11.1.1 | 0.710 | |
| 4usr | FAD | Monooxygenase | / | 0.709 | |
| 1bwc | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.708 | |
| 1n4u | FAE | Cholesterol oxidase | 1.1.3.6 | 0.708 | |
| 2igo | FAD | Pyranose 2-oxidase | / | 0.708 | |
| 2q28 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.708 | |
| 1grh | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.707 | |
| 2ba9 | FAD | Putative aminooxidase | / | 0.707 | |
| 1n4w | FAD | Cholesterol oxidase | 1.1.3.6 | 0.705 | |
| 1ng3 | FAD | Glycine oxidase | 1.4.3.19 | 0.705 | |
| 4opi | FDA | Conserved Archaeal protein | / | 0.705 | |
| 2a8x | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.704 | |
| 3ean | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.704 | |
| 2bab | FAD | Putative aminooxidase | / | 0.702 | |
| 2bi7 | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.702 | |
| 2gew | FAD | Cholesterol oxidase | 1.1.3.6 | 0.702 | |
| 3nn6 | FB0 | 6-hydroxy-L-nicotine oxidase | / | 0.702 | |
| 4yac | NAI | C alpha-dehydrogenase | / | 0.702 | |
| 2rab | FAD | Glutathione amide reductase | / | 0.701 | |
| 2rgh | FAD | Alpha-Glycerophosphate Oxidase | / | 0.701 | |
| 4ocg | FAD | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.701 | |
| 3m0o | FAD | Monomeric sarcosine oxidase | 1.5.3.1 | 0.700 | |
| 4eqs | FAD | Coenzyme A disulfide reductase | / | 0.700 | |
| 4fx9 | FAD | Coenzyme A disulfide reductase | 1.8.1.14 | 0.700 | |
| 2xvi | FAD | Putative flavin-containing monooxygenase | / | 0.699 | |
| 3gyj | FAD | Cholesterol oxidase | 1.1.3.6 | 0.699 | |
| 1ger | FAD | Glutathione reductase | 1.8.1.7 | 0.698 | |
| 1w4x | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.698 | |
| 3rp8 | FAD | FAD-dependent urate hydroxylase | / | 0.698 | |
| 1gpe | FAD | Glucose oxidase | 1.1.3.4 | 0.697 | |
| 2xvh | FAD | Putative flavin-containing monooxygenase | / | 0.697 | |
| 2zzc | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.697 | |
| 4pyo | SAH | Catechol O-methyltransferase | 2.1.1.6 | 0.697 | |
| 2xdo | FAD | TetX family tetracycline inactivation enzyme | / | 0.695 | |
| 3cox | FAD | Cholesterol oxidase | 1.1.3.6 | 0.695 | |
| 3lsi | FAD | Pyranose 2-oxidase | / | 0.695 | |
| 1lqu | FAD | NADPH-ferredoxin reductase FprA | 1.18.1.2 | 0.694 | |
| 1yqz | FAD | Coenzyme A disulfide reductase | / | 0.694 | |
| 2b9y | FAD | Putative aminooxidase | / | 0.694 | |
| 2eq7 | NAD | Dihydrolipoyl dehydrogenase | / | 0.694 | |
| 3up4 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.694 | |
| 4eqw | FAD | Coenzyme A disulfide reductase | / | 0.694 | |
| 3lb8 | FAD | Putidaredoxin reductase | 1.18.1.5 | 0.693 | |
| 4cnj | FAD | L-amino acid oxidase | / | 0.693 | |
| 1gte | FAD | Dihydropyrimidine dehydrogenase [NADP(+)] | 1.3.1.2 | 0.692 | |
| 3kpk | FAD | Sulfide-quinone reductase | / | 0.692 | |
| 3t2z | FAD | Sulfide-quinone reductase | / | 0.692 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.691 | |
| 3k30 | ADP | Histamine dehydrogenase | / | 0.691 | |
| 3m12 | FAD | Monomeric sarcosine oxidase | 1.5.3.1 | 0.691 | |
| 3sqp | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.691 | |
| 3t2y | FAD | Sulfide-quinone reductase | / | 0.691 | |
| 5er0 | FAD | Uncharacterized NAD(FAD)-dependent dehydrogenase | / | 0.691 | |
| 1d4d | FAD | Fumarate reductase flavoprotein subunit | 1.3.5.4 | 0.690 | |
| 2tmd | ADP | Trimethylamine dehydrogenase | 1.5.8.2 | 0.690 | |
| 3u81 | SAH | Catechol O-methyltransferase | 2.1.1.6 | 0.690 | |
| 4iv8 | SAM | Phosphoethanolamine N-methyltransferase,putative | / | 0.690 | |
| 5hhf | FDA | UDP-galactopyranose mutase | / | 0.690 | |
| 1h81 | FAD | Polyamine oxidase | 1.5.3.14 | 0.689 | |
| 4ap3 | FAD | Steroid monooxygenase | / | 0.689 | |
| 4eqx | FAD | Coenzyme A disulfide reductase | / | 0.689 | |
| 2ibt | NEA | Modification methylase TaqI | 2.1.1.72 | 0.688 | |
| 2v6o | FAD | Thioredoxin glutathione reductase | / | 0.688 | |
| 3g5q | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.688 | |
| 2ih2 | NEA | Modification methylase TaqI | 2.1.1.72 | 0.687 | |
| 2o06 | MTA | Spermidine synthase | 2.5.1.16 | 0.687 | |
| 3cn8 | FAD | Polyamine oxidase FMS1 | / | 0.687 | |
| 1e1m | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.686 | |
| 2x3n | FAD | Probable FAD-dependent monooxygenase | / | 0.686 | |
| 3fbs | FAD | Oxidoreductase | / | 0.686 | |
| 4guv | FAD | TetX family tetracycline inactivation enzyme | / | 0.686 | |
| 1mxt | FAE | Cholesterol oxidase | 1.1.3.6 | 0.685 | |
| 1zmc | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.685 | |
| 2hnk | SAH | SAM-dependent O-methyltransferase | / | 0.685 | |
| 2npx | FAD | NADH peroxidase | 1.11.1.1 | 0.684 | |
| 3kpf | FAD | Polyamine oxidase | 1.5.3.14 | 0.684 | |
| 3uoz | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.684 | |
| 1gxf | FAD | Trypanothione reductase | 1.8.1.12 | 0.683 | |
| 3gdp | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.683 | |
| 4bk2 | FAD | Probable salicylate monooxygenase | / | 0.683 | |
| 4em4 | FAD | Coenzyme A disulfide reductase | / | 0.683 | |
| 4mo2 | FAD | UDP-galactopyranose mutase | / | 0.683 | |
| 4em3 | FAD | Coenzyme A disulfide reductase | / | 0.682 | |
| 4j36 | FAD | Kynurenine 3-monooxygenase | / | 0.682 | |
| 4xxg | FAD | Cholesterol oxidase | 1.1.3.6 | 0.682 | |
| 2gmh | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.681 | |
| 3epp | SFG | mRNA cap guanine-N7 methyltransferase | 2.1.1.56 | 0.681 | |
| 5fa5 | MTA | Protein arginine N-methyltransferase 5 | / | 0.681 | |
| 1tdk | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.680 | |
| 2yr4 | FAD | Phenylalanine 2-monooxygenase precursor | 1.13.12.9 | 0.680 | |
| 3grv | ADN | Probable ribosomal RNA small subunit methyltransferase A | / | 0.679 | |
| 3lov | FAD | Protoporphyrinogen oxidase | / | 0.679 | |
| 3ukl | FAD | UDP-galactopyranose mutase | / | 0.679 | |
| 3zdn | FAD | Monoamine oxidase N | 1.4.3.4 | 0.679 | |
| 4gur | FAD | Lysine-specific histone demethylase 1B | 1 | 0.679 | |
| 2c7g | FAD | NADPH-ferredoxin reductase FprA | 1.18.1.2 | 0.678 | |
| 2wsb | NAD | Galactitol dehydrogenase | / | 0.678 | |
| 2xls | FAD | Putative flavin-containing monooxygenase | / | 0.678 | |
| 3pgx | NAD | Uncharacterized NAD-dependent oxidoreductase MAP_4146 | / | 0.678 | |
| 1e1k | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.677 | |
| 2rgj | FAD | Flavin-containing monooxygenase | / | 0.677 | |
| 2v7g | NAD | Urocanate hydratase | 4.2.1.49 | 0.677 | |
| 4txi | FAD | [F-actin]-methionine sulfoxide oxidase MICAL1 | 1.14.13 | 0.677 | |
| 1djn | ADP | Trimethylamine dehydrogenase | 1.5.8.2 | 0.676 | |
| 1e1n | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.676 | |
| 1gal | FAD | Glucose oxidase | 1.1.3.4 | 0.676 | |
| 1k4q | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.676 | |
| 2x8h | FAD | Thioredoxin glutathione reductase | / | 0.676 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.676 | |
| 3ldf | SAH | Uncharacterized protein | / | 0.676 | |
| 4nte | FAD | DepH | / | 0.676 | |
| 1boo | SAH | Modification methylase PvuII | 2.1.1.113 | 0.675 | |
| 2dw4 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.675 | |
| 3lxd | FAD | FAD-dependent pyridine nucleotide-disulfide oxidoreductase | / | 0.675 | |
| 3t2k | FAD | Sulfide-quinone reductase | / | 0.675 | |
| 4o5q | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.675 | |
| 4wec | NAD | Short chain dehydrogenase | / | 0.675 | |
| 1o94 | ADP | Trimethylamine dehydrogenase | 1.5.8.2 | 0.674 | |
| 3dk4 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.674 | |
| 3ihg | FAD | Aklavinone 12-hydroxylase RdmE | / | 0.674 | |
| 3jyp | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.674 | |
| 4gbe | SAH | DNA adenine methylase | 2.1.1.72 | 0.674 | |
| 4qi5 | FAD | Cellobiose dehydrogenase | / | 0.674 | |
| 2eq8 | FAD | Dihydrolipoyl dehydrogenase | / | 0.673 | |
| 4gus | FAD | Lysine-specific histone demethylase 1B | 1 | 0.673 | |
| 4usq | FAD | Pyridine nucleotide-disulfide oxidoreductase | / | 0.673 | |
| 3a26 | MTA | tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase | / | 0.672 | |
| 4bk3 | FAD | Probable salicylate monooxygenase | / | 0.672 | |
| 4la1 | FAD | Thioredoxin glutathione reductase | / | 0.672 | |
| 1p1i | NAD | Inositol-3-phosphate synthase | 5.5.1.4 | 0.671 | |
| 4c03 | SFG | Protein arginine N-methyltransferase 6 | / | 0.671 | |
| 4hsu | FAD | Lysine-specific histone demethylase 1B | 1 | 0.671 | |
| 1h2h | NAD | L-aspartate dehydrogenase | 1.4.1.21 | 0.670 | |
| 1nw6 | SFG | Modification methylase RsrI | 2.1.1.72 | 0.670 | |
| 3g07 | SAM | 7SK snRNA methylphosphate capping enzyme | 2.1.1 | 0.670 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.669 | |
| 3s55 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.669 | |
| 4jn9 | FAD | DepH | / | 0.669 | |
| 3f8p | NAD | NADH oxidase/thioredoxin reductase | / | 0.668 | |
| 3uka | FAD | UDP-galactopyranose mutase | / | 0.668 | |
| 2eq6 | FAD | Dihydrolipoyl dehydrogenase | / | 0.667 | |
| 2ih5 | NEA | Modification methylase TaqI | 2.1.1.72 | 0.667 | |
| 2wow | FAD | Trypanothione reductase | / | 0.667 | |
| 3qvr | FAD | Glucose oxidase | 1.1.3.4 | 0.667 | |
| 4hc4 | SAH | Protein arginine N-methyltransferase 6 | / | 0.667 | |
| 1d4c | FAD | Fumarate reductase flavoprotein subunit | 1.3.5.4 | 0.666 | |
| 1i9g | SAM | tRNA (adenine(58)-N(1))-methyltransferase TrmI | / | 0.666 | |
| 4xwr | FAD | Cholesterol oxidase | 1.1.3.6 | 0.666 | |
| 5l3d | FAD | Lysine-specific histone demethylase 1A | 1 | 0.666 | |
| 1h6v | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.665 | |
| 3k7t | FAD | 6-hydroxy-L-nicotine oxidase | / | 0.665 | |
| 1skm | SAH | Modification methylase HhaI | 2.1.1.37 | 0.664 | |
| 2x8g | FAD | Thioredoxin glutathione reductase | / | 0.664 | |
| 2z6u | SAH | Modification methylase HhaI | 2.1.1.37 | 0.664 | |
| 3fpf | MTA | Uncharacterized protein | / | 0.664 | |
| 1djq | ADP | Trimethylamine dehydrogenase | 1.5.8.2 | 0.663 | |
| 3wv8 | ATP | Hmd co-occurring protein HcgE | / | 0.663 | |
| 4ccq | FAD | Thioredoxin reductase | / | 0.663 | |
| 4emw | FAD | Coenzyme A disulfide reductase | / | 0.663 | |
| 1cjc | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.662 | |
| 2c7q | SAH | Modification methylase HhaI | 2.1.1.37 | 0.662 | |
| 2ji9 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.662 | |
| 2p35 | SAH | Trans-aconitate 2-methyltransferase | / | 0.662 | |
| 3mht | SAH | Modification methylase HhaI | 2.1.1.37 | 0.662 | |
| 4j34 | FAD | Kynurenine 3-monooxygenase | / | 0.662 | |
| 1jnz | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.661 | |
| 2i9k | SAH | Modification methylase HhaI | 2.1.1.37 | 0.661 | |
| 4bjz | FAD | Probable salicylate monooxygenase | / | 0.661 | |
| 4g73 | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.661 | |
| 4u8o | FDA | UDP-galactopyranose mutase | / | 0.661 | |
| 4xbf | FAD | Lysine-specific histone demethylase 1A | 1 | 0.661 | |
| 4ysh | FAD | Glycine oxidase | / | 0.661 | |
| 1ahh | NAD | 7-alpha-hydroxysteroid dehydrogenase | 1.1.1.159 | 0.660 | |
| 1cf3 | FAD | Glucose oxidase | 1.1.3.4 | 0.660 | |
| 1mo9 | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.660 | |
| 4rls | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.660 | |
| 2bh2 | SAH | 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD | / | 0.659 | |
| 2ji7 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.659 | |
| 2ore | SAH | DNA adenine methylase | 2.1.1.72 | 0.659 | |
| 5br7 | FAD | UDP-galactopyranose mutase | / | 0.659 | |
| 2uyh | SAH | Modification methylase HhaI | 2.1.1.37 | 0.658 | |
| 3c96 | FAD | Flavin-containing monooxygenase | / | 0.658 | |
| 2zth | SAM | Catechol O-methyltransferase | 2.1.1.6 | 0.657 | |
| 3dgz | FAD | Thioredoxin reductase 2, mitochondrial | 1.8.1.9 | 0.657 | |
| 4j57 | FAD | Thioredoxin reductase 2 | 1.8.1.9 | 0.657 | |
| 1tdn | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.656 | |
| 1zq9 | SAM | Probable dimethyladenosine transferase | / | 0.656 | |
| 2aot | SAH | Histamine N-methyltransferase | 2.1.1.8 | 0.656 | |
| 2hmv | ADP | Ktr system potassium uptake protein A | / | 0.656 | |
| 2ji6 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.656 | |
| 3ukf | FDA | UDP-galactopyranose mutase | / | 0.656 | |
| 4cy8 | FDA | 2-hydroxybiphenyl-3-monooxygenase | / | 0.656 | |
| 2j3n | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.655 | |
| 3h5n | ATP | MccB protein | / | 0.655 | |
| 5fs7 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.655 | |
| 1f8r | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.654 | |
| 2fja | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.654 | |
| 3axb | FAD | Putative oxidoreductase | / | 0.654 | |
| 4opl | FDA | Conserved Archaeal protein | / | 0.654 | |
| 5c2t | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.654 | |
| 1v0j | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.653 | |
| 2gqw | FAD | Ferredoxin reductase | / | 0.653 | |
| 2gr3 | FAD | Ferredoxin reductase | / | 0.653 | |
| 2jib | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.653 | |
| 3nt4 | NAI | Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase | 1.1.1.18 | 0.653 | |
| 4xcx | SAH | Small RNA 2'-O-methyltransferase | / | 0.653 | |
| 1v59 | NAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.652 | |
| 1wam | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.652 | |
| 1wg8 | SAM | Ribosomal RNA small subunit methyltransferase H | / | 0.652 | |
| 1yy5 | FAD | Polyamine oxidase FMS1 | / | 0.652 | |
| 2f5z | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.652 | |
| 2pwy | SAH | tRNA (adenine(58)-N(1))-methyltransferase TrmI | 2.1.1.220 | 0.652 | |
| 2yvl | SAM | tRNA (adenine(58)-N(1))-methyltransferase TrmI | / | 0.652 | |
| 3bi5 | FAD | Polyamine oxidase FMS1 | / | 0.652 | |
| 3c3y | SAH | O-methyltransferase | / | 0.652 | |
| 4j49 | NAI | Uncharacterized protein | / | 0.652 | |
| 5hxw | FAD | L-amino acid deaminase | / | 0.652 | |
| 5j60 | FAD | Thioredoxin reductase | / | 0.652 | |
| 4c3y | FAD | 3-ketosteroid dehydrogenase | / | 0.651 | |
| 4gde | FDA | UDP-galactopyranose mutase | / | 0.651 | |
| 4j43 | NAD | Uncharacterized protein | / | 0.651 | |
| 4j49 | NAD | Uncharacterized protein | / | 0.651 | |
| 4z26 | FAD | Putative GMC-type oxidoreductase R135 | 1 | 0.651 | |
| 9mht | SAH | Modification methylase HhaI | 2.1.1.37 | 0.651 | |
| 2eq9 | FAD | Dihydrolipoyl dehydrogenase | / | 0.650 | |
| 3nwe | 662 | Catechol O-methyltransferase | 2.1.1.6 | 0.650 | |
| 4yuz | S4M | Spermidine synthase, putative | / | 0.650 |