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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4ck2NVUIntegrase

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
4ck2NVUIntegrase/1.000
3zt0ZT0Integrase/0.616
4cggK5QIntegrase/0.610
4cfaWOPIntegrase/0.602
4cfc7NVIntegrase/0.601
4cghLOZIntegrase/0.597
4cifJDXIntegrase/0.593
4cgd8P3Integrase/0.591
4cjp4D2Integrase/0.591
4cj3E4FIntegrase/0.590
4cf23GMIntegrase/0.588
4cfdS8YIntegrase/0.588
4cigX0PIntegrase/0.584
4cgjNZLIntegrase/0.581
4cfbOM3Integrase/0.580
4ceqQCHIntegrase/0.579
4cjrFYMIntegrase/0.579
4cjkH39Integrase/0.577
3zsrO3NIntegrase/0.575
4cezO3NIntegrase/0.575
4cjqVXOIntegrase/0.575
4ce9O3NIntegrase/0.574
4ced9NSIntegrase/0.572
4cf0O5UIntegrase/0.572
3zswZSWIntegrase/0.571
4cefD0TIntegrase/0.571
3zsyOM3Integrase/0.570
4cesNFWIntegrase/0.570
4ceaZSWIntegrase/0.567
4cieY7NIntegrase/0.567
4cec2SSIntegrase/0.562
4cjuJNSIntegrase/0.559
4ck3K1TIntegrase/0.559
4cgiNZLIntegrase/0.556
4cj4S3GIntegrase/0.556
4cj54VWIntegrase/0.556
4chyC5QIntegrase/0.552
4cjeQ31Integrase/0.552
4cf1IY7Integrase/0.548
3zt1OM1Integrase/0.547
4ck1OM1Integrase/0.547
4cerVL4Integrase/0.544
4cf8V7HIntegrase/0.544
4cjsL0YIntegrase/0.542
3zt3ZT4Integrase/0.539
3zt2ZT2Integrase/0.536
4ceoG0TIntegrase/0.536
3zsqO4NIntegrase/0.533
3zsvZSVIntegrase/0.528
4cebZSVIntegrase/0.528
3zszOM2Integrase/0.527
4cjfRVNIntegrase/0.527
3zcmPX3Integrase/0.519
4chqCWUIntegrase/0.518
4ceeB0TIntegrase/0.516
3bhtMFRCyclin-dependent kinase 22.7.11.220.515
3zsxN44Integrase/0.513
3hadNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.508
2gnhH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.490
1xe65FPPlasmepsin-23.4.23.390.488
2rhgIGPTryptophan synthase alpha chain/0.485
2ohvNHLGlutamate racemase/0.483
3p67FMNPentaerythritol tetranitrate reductase/0.483
4fxy0W2Neurolysin, mitochondrial3.4.24.160.482
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.481
3p4tFAOPutative acyl-CoA dehydrogenase/0.481
1p0pBCHCholinesterase3.1.1.80.479
5ar4SB2Receptor-interacting serine/threonine-protein kinase 22.7.11.10.479
1bwsNDPGDP-L-fucose synthase/0.478
1kfbIGPTryptophan synthase alpha chain/0.478
1h51FMNPentaerythritol tetranitrate reductase/0.476
1zrzBI1Protein kinase C iota type2.7.11.130.476
2qo5CHDFatty acid-binding protein 10-A, liver basic/0.475
2w9hTOPDihydrofolate reductase1.5.1.30.475
3p82FMNPentaerythritol tetranitrate reductase/0.474
4c02TAKActivin receptor type-12.7.11.300.474
4rrvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.474
3em3478Gag-Pol polyprotein3.4.23.160.473
2vtiLZ3Cyclin-dependent kinase 22.7.11.220.472
2xj2985Serine/threonine-protein kinase pim-12.7.11.10.472
2z54AB1Gag-Pol polyprotein3.4.23.160.472
3bv7NAP3-oxo-5-beta-steroid 4-dehydrogenase/0.472
4jx1CAHCamphor 5-monooxygenase1.14.15.10.472
1je1GMPPurine nucleoside phosphorylase/0.471
1mg5NAIAlcohol dehydrogenase1.1.1.10.471
3mg3ECHOrange carotenoid-binding protein/0.471
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.470
3flyFLYMitogen-activated protein kinase 14/0.470
3fskRO6Mitogen-activated protein kinase 14/0.470
4dptAGSMevalonate diphosphate decarboxylase/0.470
4g2rH1LProbable propionyl-CoA carboxylase beta chain 66.4.1.30.470
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.469
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.469
3lqfNADGalactitol dehydrogenase/0.469
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.469
4cr8NADN-acylmannosamine 1-dehydrogenase1.1.1.2330.469
1vyrFMNPentaerythritol tetranitrate reductase/0.468
2briANPUridylate kinase2.7.4.220.468
3eyhIZATyrosine-protein kinase JAK1/0.468
3pwm017Gag-Pol polyprotein3.4.23.160.468
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.468
2hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.467
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.467
2zbaZBATrichothecene 3-O-acetyltransferase/0.467
3qt62P0Mevalonate diphosphate decarboxylase/0.467
4dymIYZActivin receptor type-12.7.11.300.467
1h50FMNPentaerythritol tetranitrate reductase/0.466
1kfcIPLTryptophan synthase alpha chain/0.466
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.466
2rh9IGPTryptophan synthase alpha chain/0.466
3gu83GUDeath-associated protein kinase 12.7.11.10.466
4bzo676Serine/threonine-protein kinase pim-12.7.11.10.466
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.466
1rx8NAPDihydrofolate reductase1.5.1.30.465
1vikBAYGag-Pol polyprotein/0.465
1zemNADXylitol dehydrogenase/0.465
4nm9FADBifunctional protein PutA/0.465
1ia1NDPDihydrofolate reductase1.5.1.30.464
1qy5NECEndoplasmin/0.464
2ien017Gag-Pol polyprotein3.4.23.160.464
2qo9ANPEphrin type-A receptor 32.7.10.10.464
3r7kFDAProbable acyl CoA dehydrogenase/0.464
2ab8MTPAdenosine kinase2.7.1.200.463
2brbPFQSerine/threonine-protein kinase Chk12.7.11.10.463
4e2dFMNDehydrogenase/0.463
4v0s2HN3-dehydroquinate dehydratase4.2.1.100.463
1foaUD1Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase2.4.1.1010.462
1gzuNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.462
2abbFMNPentaerythritol tetranitrate reductase/0.462
2bkzSBCCyclin-dependent kinase 22.7.11.220.462
1drhNAPDihydrofolate reductase1.5.1.30.461
1eioGCHGastrotropin/0.461
1kvsUPGUDP-glucose 4-epimerase5.1.3.20.461
2ejvNADL-threonine 3-dehydrogenase/0.461
3ivgFG5Pantothenate synthetase6.3.2.10.461
3mpjFADGlutaryl-CoA dehydrogenase1.3.99.320.461
3vdqNAD3-hydroxybutyrate dehydrogenase/0.461
4ct1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.461
4nd2A3DLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.461
4q72FADBifunctional protein PutA/0.461
1svmATPLarge T antigen3.6.40.460
1u33LM2Pancreatic alpha-amylase/0.460
1u7tNAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.460
1xe55FEPlasmepsin-23.4.23.390.460
3d7kD7KBenzaldehyde lyase/0.460
3ibqATPPyridoxal kinase/0.460
4bibIEOMitogen-activated protein kinase kinase kinase 52.7.11.250.460
4hp8NAP2-deoxy-D-gluconate 3-dehydrogenase/0.460
5e8wSTUTGF-beta receptor type-12.7.11.300.460
1j49NADD-lactate dehydrogenase1.1.1.280.459
1nq5NADGlyceraldehyde-3-phosphate dehydrogenase/0.459
2q2qNADBeta-D-hydroxybutyrate dehydrogenase/0.459
2uztSS3cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.459
3atzFMNProstaglandin F2a synthase/0.459
3fklFKLMitogen-activated protein kinase 14/0.459
3iphG11Mitogen-activated protein kinase 14/0.459
4ewn0VRImidazole glycerol phosphate synthase subunit HisF4.1.30.459
4gk3L87Ephrin type-A receptor 32.7.10.10.459
1dirNADDihydropteridine reductase1.5.1.340.458
1hbvGANGag-Pol polyprotein/0.458
1kp2ATPArgininosuccinate synthase6.3.4.50.458
1lrjUD1UDP-glucose 4-epimerase5.1.3.20.458
1tqf32PBeta-secretase 13.4.23.460.458
1u30GOXPancreatic alpha-amylase/0.458
1u54ACPActivated CDC42 kinase 1/0.458
2br1PFPSerine/threonine-protein kinase Chk12.7.11.10.458
4bznUGXSerine/threonine-protein kinase pim-12.7.11.10.458
4q73FADBifunctional protein PutA/0.458
5il2SAHN6-adenosine-methyltransferase 70 kDa subunit/0.458
1t2dNADL-lactate dehydrogenase1.1.1.270.457
2z52H23Geranylgeranyl pyrophosphate synthase/0.457
3a3yOBNSodium/potassium-transporting ATPase subunit alpha/0.457
3drcMTXDihydrofolate reductase1.5.1.30.457
3iaeD7KBenzaldehyde lyase/0.457
4hmz18TdTDP-4-dehydro-6-deoxyglucose 3-epimerase5.1.3.270.457
4j8tDOGUncharacterized PhzA/B-like protein PA3332/0.457
1w6hTITPlasmepsin-23.4.23.390.456
1y57MPZProto-oncogene tyrosine-protein kinase Src2.7.10.20.456
3fp0FP015-O-acetyltransferase/0.456
4hyh1AMSerine/threonine-protein kinase Chk12.7.11.10.456
4nbtNAD3-oxoacyl-[acyl-carrier-protein] reductase/0.456
1ay0TPPTransketolase 12.2.1.10.455
1dyjDDFDihydrofolate reductase1.5.1.30.455
1f8fNADBenzyl alcohol dehydrogenase/0.455
1u4oNDDL-lactate dehydrogenase1.1.1.270.455
2bxmIMNSerum albumin/0.455
2e9oA58Serine/threonine-protein kinase Chk12.7.11.10.455
2p3b3TLV-1 PROTEASE protein/0.455
2p3b3TLV-1 protease/0.455
3dt1P40Mitogen-activated protein kinase 14/0.455
3opxU5PSuppressor of disruption of TFIIS/0.455
4fv6E57Mitogen-activated protein kinase 12.7.11.240.455
4l4xNDPAmphI/0.455
4wda2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.455
4wecNADShort chain dehydrogenase/0.455
1e8xATPPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.454
1m78NDPDihydrofolate reductase1.5.1.30.454
1rx1NAPDihydrofolate reductase1.5.1.30.454
2c3kABOSerine/threonine-protein kinase Chk12.7.11.10.454
2ojtUBAGlutamate receptor ionotropic, kainate 1/0.454
3em0CHDFatty acid-binding protein 6, ileal (gastrotropin)/0.454
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.454
4cukNAID-lactate dehydrogenase/0.454
4eplJAIJasmonic acid-amido synthetase JAR16.3.20.454
1di8DTQCyclin-dependent kinase 22.7.11.220.453
1hdcCBO3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.453
1mokFAD2-oxopropyl-CoM reductase, carboxylating1.8.1.50.453
2a7r5GPGMP reductase 2/0.453
2c29NAPDihydroflavonol 4-reductase/0.453
2c31TZDOxalyl-CoA decarboxylase4.1.1.80.453
2eklNADD-3-phosphoglycerate dehydrogenase/0.453
2i4xKGQProtease/0.453
2oc4IMHPurine nucleoside phosphorylase2.4.2.10.453
2p9gNAID-3-phosphoglycerate dehydrogenase1.1.1.950.453
2v13C40Renin3.4.23.150.453
2wxvWXVCyclin-dependent kinase 22.7.11.220.453
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.453
3o03NAPDehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase)/0.453
3p62FMNPentaerythritol tetranitrate reductase/0.453
3vyfVYFRenin3.4.23.150.453
4b8wNAPGDP-L-fucose synthase1.1.1.2710.453
4bcaFADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.453
5fwnNAPPutative dehydrogenase/0.453
1powFADPyruvate oxidase1.2.3.30.452
2g1n1IGRenin3.4.23.150.452
3kgaLX9MAP kinase-activated protein kinase 22.7.11.10.452
3mtfA3FActivin receptor type-12.7.11.300.452
3orfNADDihydropteridine reductase1.5.1.340.452
3s1dZIRCytokinin dehydrogenase 11.5.99.120.452
3zw9NADPeroxisomal bifunctional enzyme1.1.1.350.452
4cgfUJ6Integrase/0.452
4g2fC07Ephrin type-A receptor 32.7.10.10.452
4k6fNAPPutative Acetoacetyl-CoA reductase/0.452
4mlp2CXCryptochrome-2/0.452
1gcoNADGlucose 1-dehydrogenase1.1.1.470.451
1k8y13PTryptophan synthase alpha chain/0.451
1kvuUPGUDP-glucose 4-epimerase5.1.3.20.451
1sowNADL-lactate dehydrogenase1.1.1.270.451
1z1rHBHGag-Pol polyprotein3.4.23.160.451
2c27ACOMycothiol acetyltransferase2.3.1.1890.451
2nnlNAPDihydroflavonol 4-reductase1.1.1.2190.451
3cscACOCitrate synthase, mitochondrial2.3.3.10.451
3f1kNAPUncharacterized oxidoreductase YciK10.451
3jyqNADQuinate/shikimate dehydrogenase (NAD(+))/0.451
3lfm3DTAlpha-ketoglutarate-dependent dioxygenase FTO/0.451
3owaFADAcyl-CoA dehydrogenase/0.451
4a802ANMajor pollen allergen Bet v 1-A/0.451
4ew2DXYTrifunctional purine biosynthetic protein adenosine-32.1.2.20.451
4fw8NAI3-oxoacyl-(Acyl-carrier-protein) reductase/0.451
4kip1R9Mitogen-activated protein kinase 14/0.451
4rqkATP3-phosphoinositide-dependent protein kinase 12.7.11.10.451
1f5fDHTSex hormone-binding globulin/0.450
1rx8FOLDihydrofolate reductase1.5.1.30.450
1u2yGOXPancreatic alpha-amylase/0.450
1vi2NADQuinate/shikimate dehydrogenase/0.450
2jdsL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.450
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.450
2p5uNADUDP-glucose 4-epimerase/0.450
3fwjCAMCamphor 5-monooxygenase1.14.15.10.450
3u9eCOALmo1369 protein/0.450
4a83DXCMajor pollen allergen Bet v 1-A/0.450
4aqc88ATyrosine-protein kinase JAK2/0.450
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.450
4c36ZO9cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.450
4dfg0JVGag-Pol polyprotein3.4.23.160.450
4eu9COASuccinyl-CoA:acetate CoA-transferase/0.450
4jicFMNGTN Reductase/0.450
4qq3XMPInosine-5'-monophosphate dehydrogenase/0.450
1h74ADPHomoserine kinase2.7.1.390.449
1rr6IMHPurine nucleoside phosphorylase2.4.2.10.449
1siqFADGlutaryl-CoA dehydrogenase, mitochondrial1.3.8.60.449
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.449
1u8fNADGlyceraldehyde-3-phosphate dehydrogenase1.2.1.120.449
1zxmANPDNA topoisomerase 2-alpha5.99.1.30.449
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.449
2g8yNADHydroxycarboxylate dehydrogenase B/0.449
2gjnFMNNitronate monooxygenase1.13.12.160.449
2qs4LY5Glutamate receptor ionotropic, kainate 1/0.449
2vwqNAPGlucose 1-dehydrogenase/0.449
2ztvNADD(-)-3-hydroxybutyrate dehydrogenase/0.449
3akzGSUGlutamate--tRNA ligase 2/0.449
3koo24DBifunctional epoxide hydrolase 23.3.2.100.449
3lzs017Gag-Pol polyprotein3.4.23.160.449
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.449
4dbzNDPPutative ketoacyl reductase1.3.10.449
4i8zG08Gag-Pol polyprotein3.4.23.160.449
4pghSAMCaffeic acid O-methyltransferase/0.449
4z63ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.449
1i7pFADNADH-cytochrome b5 reductase 31.6.2.20.448
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.448
1ra3MTXDihydrofolate reductase1.5.1.30.448
2bbwGP5Adenylate kinase 4, mitochondrial/0.448
2d1yNADOxidoreductase, short-chain dehydrogenase/reductase family/0.448
2qs3UBEGlutamate receptor ionotropic, kainate 1/0.448
3cxw7CPSerine/threonine-protein kinase pim-12.7.11.10.448
3n0tOPYDipeptidyl peptidase 23.4.14.20.448
3s56ROCProtease/0.448
3vjoANPEpidermal growth factor receptor2.7.10.10.448
4bgg844Activin receptor type-12.7.11.300.448
4cvmANPUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase/0.448
4enhFVXCholesterol 24-hydroxylase/0.448
4fizCUE17beta-hydroxysteroid dehydrogenase/0.448
4zj8SUVOrexin receptor type 1/0.448
1bdlIM1Gag-Pol polyprotein3.4.23.160.447
1e81M91Endothiapepsin3.4.23.220.447
1eh4IC1Casein kinase I homolog 12.7.11.10.447
1f17NAIHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.447
1h62ANBPentaerythritol tetranitrate reductase/0.447
1t2cNAIL-lactate dehydrogenase1.1.1.270.447
1zthADPRIO-type serine/threonine-protein kinase Rio12.7.11.10.447
2dvlFADAcyl-CoA dehydrogenase/0.447
2i65NADADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 13.2.2.60.447
2ii5CO6Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial2.3.1.1680.447
2ji9TPWOxalyl-CoA decarboxylase4.1.1.80.447
2lfoGCHFatty acid-binding protein, liver/0.447
2pvnP63Casein kinase II subunit alpha2.7.11.10.447
2vigFADShort-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.10.447
3au8NDP1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic1.1.1.2670.447
3cy2MB9Serine/threonine-protein kinase pim-12.7.11.10.447
3hrfATP3-phosphoinositide-dependent protein kinase 12.7.11.10.447
3r9uFADThioredoxin reductase/0.447
3sheI85MAP kinase-activated protein kinase 32.7.11.10.447
3sudSUEPolyprotein/0.447
3toxNAPPutative oxidoreductase/0.447
4bfzZVZPantothenate kinase2.7.1.330.447
4jhz1KVBeta-glucuronidase3.2.1.310.447
4nd4NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.447
4z64ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.447
1a72PADAlcohol dehydrogenase E chain1.1.1.10.446
1bvrTHTEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.446
1d4aFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.446
1phhFADp-hydroxybenzoate hydroxylase/0.446
2brnDF1Serine/threonine-protein kinase Chk12.7.11.10.446
2fn7NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.446
2vtnLZ7Cyclin-dependent kinase 22.7.11.220.446
2wnsOMPUridine 5'-monophosphate synthase2.4.2.100.446
2wpa889Cyclin-dependent kinase 22.7.11.220.446
2z4sADPChromosomal replication initiator protein DnaA/0.446
3bwcSAMSpermidine synthase, putative/0.446
3hrcATP3-phosphoinositide-dependent protein kinase 12.7.11.10.446
3qlrNDPDihydrofolate reductase1.5.1.30.446
4f0e0RUPoly [ADP-ribose] polymerase 152.4.2.300.446
4p8rNADGlyceraldehyde-3-phosphate dehydrogenase/0.446
5dp2NAPCurF/0.446
1cs4FOKAdenylate cyclase type 2/0.445
1cs4FOKAdenylate cyclase type 5/0.445
1dbvNADGlyceraldehyde-3-phosphate dehydrogenase/0.445
1e3sNAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.445
1fm4DXCMajor pollen allergen Bet v 1-L/0.445
1h63FMNPentaerythritol tetranitrate reductase/0.445
1h74AGSHomoserine kinase2.7.1.390.445
1jg0DDTThymidylate synthase/0.445
1kquBR4Phospholipase A2, membrane associated/0.445
1ny3ADPMAP kinase-activated protein kinase 22.7.11.10.445
1tqpATPRIO-type serine/threonine-protein kinase Rio22.7.11.10.445
1uyuCAMCamphor 5-monooxygenase1.14.15.10.445
2ed4NAD4-hydroxyphenylacetate 3-monooxygenase reductase component1.5.1.360.445
3c16FOKAdenylate cyclase type 2/0.445
3c16FOKAdenylate cyclase type 5/0.445
3cd3STUTyrosine-protein kinase Fes/Fps2.7.10.20.445
3dv3MEKDual specificity mitogen-activated protein kinase kinase 12.7.12.20.445
3ecg065Gag-Pol polyprotein3.4.23.470.445
3fr8NDPKetol-acid reductoisomerase, chloroplastic1.1.1.860.445
3o0qADNVitamin B12-dependent ribonucleotide reductase/0.445
3upkUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.445
4k28NADShikimate dehydrogenase family protein/0.445
4o0rX4ZSerine/threonine-protein kinase PAK 12.7.11.10.445
4q71FADBifunctional protein PutA/0.445
4xcvNDPProbable hydroxyacid dehydrogenase protein/0.445
4z61ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.445
5b1yNDP3-oxoacyl-[acyl-carrier-protein] reductase/0.445
1cqp803Integrin alpha-L/0.444
1fmjRTLRetinol dehydratase/0.444
1jpaANPEphrin type-B receptor 22.7.10.10.444
1ps9MDE2,4-dienoyl-CoA reductase1.3.1.340.444
1rdwLARActin, alpha skeletal muscle/0.444
1s20NAD2,3-diketo-L-gulonate reductase1.1.1.1300.444
1t88CAMCamphor 5-monooxygenase1.14.15.10.444
2g5w8PG12-oxophytodienoate reductase 31.3.1.420.444
2i0aMUIProtease/0.444
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.444
2yd0BESEndoplasmic reticulum aminopeptidase 13.4.110.444
2znq401Peroxisome proliferator-activated receptor delta/0.444
3a60STURibosomal protein S6 kinase beta-12.7.11.10.444
3bxsDRSGag-Pol polyprotein3.4.23.160.444
3cgtBCDCyclomaltodextrin glucanotransferase2.4.1.190.444
3d1xROCGag-Pol polyprotein3.4.23.160.444
3fhxPLPPyridoxal kinase2.7.1.350.444
3h3t16HCollagen type IV alpha-3-binding protein/0.444
3i2l2NCProtease/0.444
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.444
3idsNADGlyceraldehyde-3-phosphate dehydrogenase, glycosomal1.2.1.120.444
3mvm39PMitogen-activated protein kinase 14/0.444
3otfCMPPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4/0.444
3r7eX88Cyclin-dependent kinase 22.7.11.220.444
3raiX85Cyclin-dependent kinase 22.7.11.220.444
3rpeFADPutative modulator of drug activity/0.444
3toh079Gag-Pol polyprotein2.7.7.490.444
4aa4QC0Mitogen-activated protein kinase 14/0.444
4g6oE28Mitogen-activated protein kinase 12.7.11.240.444
4nbwNADShort-chain dehydrogenase/reductase SDR/0.444
4x5hFOLDihydrofolate reductase1.5.1.30.444
4yntFDAGlucose oxidase, putative/0.444
5hwrCOAHydroxymethylglutaryl-CoA synthase/0.444
5jy1NADPutative short-chain dehydrogenase/reductase/0.444
1e6wNAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.443
1h65GDPTranslocase of chloroplast 343.6.50.443
1rfuADPPyridoxal kinase2.7.1.350.443
1x2hLPALipoate-protein ligase A6.3.1.200.443
2balPQAMitogen-activated protein kinase 14/0.443
2npxNADNADH peroxidase1.11.1.10.443
2vtlLZ5Cyclin-dependent kinase 22.7.11.220.443
2wihP48Cyclin-dependent kinase 22.7.11.220.443
3ai3NDPNADPH-sorbose reductase/0.443
3hztJ60Calmodulin-like domain protein kinase isoform 3/0.443
3nl6TPSUncharacterized protein/0.443
3o9dK19Pol polyprotein/0.443
3qd43Q63-phosphoinositide-dependent protein kinase 12.7.11.10.443
3tog079Gag-Pol polyprotein2.7.7.490.443
4f6w0SSCyclin-dependent kinase 82.7.11.220.443
4k9dNADGlyceraldehyde-3-phosphate dehydrogenase1.2.1.120.443
4kb9G79Protease/0.443
4qgiROCGag-Pol polyprotein3.4.23.160.443
5ackATP3-phosphoinositide-dependent protein kinase 12.7.11.10.443
1a59COA2-methylcitrate synthase/0.442
1dr2TAPDihydrofolate reductase1.5.1.30.442
1f20FADNitric oxide synthase, brain1.14.13.390.442
1fvt106Cyclin-dependent kinase 22.7.11.220.442
1kvkATPMevalonate kinase2.7.1.360.442
1tl7FOKAdenylate cyclase type 2/0.442
1tl7FOKAdenylate cyclase type 5/0.442
2acxANPG protein-coupled receptor kinase 62.7.11.160.442
2cchATPCyclin-dependent kinase 22.7.11.220.442
2d29FADAcyl-CoA dehydrogenase/0.442
2f3kRO1Protease/0.442
2gmhFADElectron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial1.5.5.10.442
2rqfJH3Hemolymph juvenile hormone binding protein/0.442
2xf3J01Uncharacterized protein/0.442
2xvu9DNSerum albumin/0.442
3dogNNNCyclin-dependent kinase 22.7.11.220.442
3dxmN24Actin-related protein 3/0.442
3e5rNADGlyceraldehyde-3-phosphate dehydrogenase 1, cytosolic1.2.1.120.442
3g5sFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.442
3gegNADShort-chain dehydrogenase/reductase SDR/0.442
3h3cP1EProtein-tyrosine kinase 2-beta2.7.10.20.442
3h3fNAIL-lactate dehydrogenase A chain1.1.1.270.442
3hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.442
3k8q22APurine nucleoside phosphorylase2.4.2.10.442
3lsiFADPyranose 2-oxidase/0.442
3lzu017Gag-Pol polyprotein3.4.23.160.442
3mzhCMPCRP-like cAMP-activated global transcriptional regulator/0.442
3nww3NWMitogen-activated protein kinase 14/0.442
3qpjN4IGag-Pol polyprotein3.4.23.160.442
3wv9FEGHmd co-occurring protein HcgE/0.442
3zuyTCHTransporter/0.442
4i6aHMG3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.880.442
5adhAPRAlcohol dehydrogenase E chain1.1.1.10.442
5ez7FADProbable FAD-dependent oxidoreductase PA4991/0.442
1bxoPP7Penicillopepsin-13.4.23.200.441
1ddsMTXDihydrofolate reductase1.5.1.30.441
1ezvUQ6Cytochrome b/0.441
1rfgGMPPurine nucleoside phosphorylase2.4.2.10.441
2ddoATPPyridoxine/pyridoxal/pyridoxamine kinase/0.441
2fdd385Pol protein/0.441
2ghlLIBMitogen-activated protein kinase 14/0.441
2hsdNAD3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.441
2nnkROCProtease/0.441
2qhyMZ1Gag-Pol polyprotein/0.441
2vtjLZ4Cyclin-dependent kinase 22.7.11.220.441
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.441
3kjiADPCO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC/0.441
3nugNADPyridoxal 4-dehydrogenase1.1.1.1070.441
3otwCOAPhosphopantetheine adenylyltransferase/0.441
3rdoBTNStreptavidin/0.441
3tm5SFGUncharacterized protein/0.441
4bfxZVXPantothenate kinase2.7.1.330.441
4fmxCNL1,8-cineole 2-endo-monooxygenase1.14.13.1560.441
4g95OAGDihydrofolate reductase1.5.1.30.441
4i13FOLDihydrofolate reductase1.5.1.30.441
1bw9NADPhenylalanine dehydrogenase/0.440
1bwlFMNNADPH dehydrogenase 11.6.99.10.440
1dr3HBIDihydrofolate reductase1.5.1.30.440
1f4eTPRThymidylate synthase/0.440
1svlADPLarge T antigen3.6.40.440
1tduDURThymidylate synthase/0.440
2bpw1INGag-Pol polyprotein3.4.23.160.440
2fypRDEEndoplasmin/0.440
2h9iEADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.440
2j2pSC2Ficolin-2/0.440
2pwcG3GGag-Pol polyprotein3.4.23.160.440
2q1sNAIPutative nucleotide sugar epimerase/ dehydratase/0.440
2x8iX8ISerine/threonine-protein kinase Chk12.7.11.10.440
2ym44YMSerine/threonine-protein kinase Chk12.7.11.10.440
3btsNADGalactose/lactose metabolism regulatory protein GAL80/0.440
3dd125DGlycogen phosphorylase, liver form2.4.1.10.440
3hllI45Mitogen-activated protein kinase 14/0.440
3m2uCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.440
3qwbNDPProbable quinone oxidoreductase1.6.5.50.440
3sc13S13-phosphoinositide-dependent protein kinase 12.7.11.10.440
3t4nADP5'-AMP-activated protein kinase subunit gamma/0.440
4d9t0JGRibosomal protein S6 kinase alpha-32.7.11.10.440
4fv3EK6Mitogen-activated protein kinase 12.7.11.240.440
4gj30XPNon-receptor tyrosine-protein kinase TYK22.7.10.20.440
4iqlFMNEnoyl-(Acyl-carrier-protein) reductase II/0.440
4pnmNU1Tankyrase-22.4.2.300.440
4y35F90Endothiapepsin3.4.23.220.440