Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3w0p | ADP | Hygromycin-B 4-O-kinase | 2.7.1.163 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3w0p | ADP | Hygromycin-B 4-O-kinase | 2.7.1.163 | 1.000 | |
| 3w0n | ANP | Hygromycin-B 4-O-kinase | 2.7.1.163 | 0.671 | |
| 3w0s | ANP | Hygromycin-B 4-O-kinase | 2.7.1.163 | 0.632 | |
| 1qpj | STU | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.508 | |
| 3a4o | STU | Tyrosine-protein kinase Lyn | 2.7.10.2 | 0.502 | |
| 4fti | H7K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.501 | |
| 4k1b | 1OC | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.501 | |
| 3w0r | ANP | Hygromycin-B 4-O-kinase | 2.7.1.163 | 0.500 | |
| 3vs3 | VSE | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.499 | |
| 3gc9 | B45 | Mitogen-activated protein kinase 11 | 2.7.11.24 | 0.495 | |
| 2izu | P01 | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.493 | |
| 4dpw | AGS | Mevalonate diphosphate decarboxylase | / | 0.492 | |
| 3lcd | BDY | Macrophage colony-stimulating factor 1 receptor | 2.7.10.1 | 0.489 | |
| 4k8a | K8A | Focal adhesion kinase 1 | 2.7.10.2 | 0.489 | |
| 4hgs | 15G | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.486 | |
| 4hle | 17V | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.486 | |
| 1pjk | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.485 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.485 | |
| 4fg7 | ATP | Calcium/calmodulin-dependent protein kinase type 1 | 2.7.11.17 | 0.484 | |
| 2bdf | 24A | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.481 | |
| 2cmw | OLP | Casein kinase I isoform gamma-1 | 2.7.11.1 | 0.479 | |
| 3a99 | ANP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.479 | |
| 4fv9 | E71 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.479 | |
| 4fsr | HKC | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.477 | |
| 2dq7 | STU | Tyrosine-protein kinase Fyn | 2.7.10.2 | 0.476 | |
| 4fr4 | STU | Serine/threonine-protein kinase 32A | 2.7.11.1 | 0.476 | |
| 4fsn | A58 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.475 | |
| 1lsj | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.474 | |
| 2izr | BRK | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.474 | |
| 4mq1 | 2C3 | Dual specificity tyrosine-phosphorylation-regulated kinase 1A | 2.7.12.1 | 0.474 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.473 | |
| 3w0o | ADP | Hygromycin-B 4-O-kinase | 2.7.1.163 | 0.472 | |
| 4bfm | ANP | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.472 | |
| 4ryv | ZEA | Protein LlR18A | / | 0.472 | |
| 1k6t | XN1 | Gag-Pol polyprotein | 3.4.23.16 | 0.471 | |
| 3ggg | NAD | Prephenate dehydrogenase | / | 0.471 | |
| 4btj | ATP | Tau-tubulin kinase 1 | 2.7.11.1 | 0.471 | |
| 4ib4 | ERM | 5-hydroxytryptamine receptor 2B | / | 0.471 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.470 | |
| 1j39 | UPG | DNA beta-glucosyltransferase | / | 0.470 | |
| 1v59 | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.470 | |
| 3igo | ANP | Calmodulin-domain protein kinase 1, putative | / | 0.470 | |
| 4fsm | HK1 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.470 | |
| 1zp9 | ATP | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.469 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.469 | |
| 3jy0 | LYG | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.469 | |
| 3ofm | 4B0 | Casein kinase II subunit alpha' | 2.7.11.1 | 0.469 | |
| 3wmx | NAD | NAD dependent epimerase/dehydratase | / | 0.469 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.468 | |
| 1yol | S03 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.468 | |
| 3g5s | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.468 | |
| 2cjm | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.467 | |
| 4agu | D15 | Cyclin-dependent kinase-like 1 | / | 0.467 | |
| 4hyu | 1BK | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.467 | |
| 1tz8 | DES | Transthyretin | / | 0.466 | |
| 2qu6 | 857 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.466 | |
| 3js2 | VM1 | Fibroblast growth factor receptor 1 | / | 0.466 | |
| 3rm6 | 18Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.466 | |
| 3vrz | VRZ | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.466 | |
| 2ym6 | YM6 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.465 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.465 | |
| 3zew | STU | Ephrin type-B receptor 4 | 2.7.10.1 | 0.465 | |
| 5cvc | PLP | Serine racemase | / | 0.465 | |
| 2om9 | AJA | Peroxisome proliferator-activated receptor gamma | / | 0.464 | |
| 2vtt | LZD | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.464 | |
| 3e8e | G98 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.464 | |
| 4dit | 0KD | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.464 | |
| 1t1r | IMB | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.463 | |
| 2ghm | LIC | Mitogen-activated protein kinase 14 | / | 0.463 | |
| 2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.463 | |
| 3wow | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.463 | |
| 4c4h | 7RO | Dual specificity protein kinase TTK | 2.7.12.1 | 0.463 | |
| 4kuh | CAA | 3-hydroxybutyryl-CoA dehydrogenase | / | 0.463 | |
| 4l49 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.463 | |
| 1fpq | SAM | Isoliquiritigenin 2'-O-methyltransferase | / | 0.462 | |
| 2hen | ADP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.462 | |
| 2j5x | GSP | ADP-ribosylation factor 6 | / | 0.462 | |
| 3w2s | W2R | Epidermal growth factor receptor | 2.7.10.1 | 0.462 | |
| 3zh8 | C58 | Protein kinase C iota type | 2.7.11.13 | 0.462 | |
| 1pl8 | NAD | Sorbitol dehydrogenase | 1.1.1.14 | 0.461 | |
| 1q99 | ANP | Serine/threonine-protein kinase SKY1 | 2.7.11.1 | 0.461 | |
| 2bts | U32 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.461 | |
| 2hog | 710 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.461 | |
| 2obj | VRV | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.461 | |
| 3gqv | NAP | Enoyl reductase LovC | 1 | 0.461 | |
| 3hcr | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.461 | |
| 4d0l | 093 | Phosphatidylinositol 4-kinase beta | 2.7.1.67 | 0.461 | |
| 4izy | 1J2 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.461 | |
| 2cgu | 3A3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.460 | |
| 2nni | MTK | Cytochrome P450 2C8 | / | 0.460 | |
| 2qoq | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.460 | |
| 3cis | ATP | Universal stress protein Rv2623 | / | 0.460 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.460 | |
| 4ft9 | H4K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.460 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.459 | |
| 3f69 | XDR | Serine/threonine-protein kinase PknB | 2.7.11.1 | 0.459 | |
| 3inm | NDP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.459 | |
| 3upk | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.459 | |
| 2hfu | MEV | Mevalonate kinase | / | 0.458 | |
| 2pyw | ADP | Methylthioribose kinase | 2.7.1.100 | 0.458 | |
| 3v9v | 21L | Peroxisome proliferator-activated receptor gamma | / | 0.458 | |
| 4ez5 | 0RS | Cyclin-dependent kinase 6 | 2.7.11.22 | 0.458 | |
| 4ix6 | ADP | Uncharacterized protein | / | 0.458 | |
| 4mcv | 29K | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.458 | |
| 4neu | Q1A | Receptor-interacting serine/threonine-protein kinase 1 | 2.7.11.1 | 0.458 | |
| 2iw8 | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.457 | |
| 2j0l | ANP | Focal adhesion kinase 1 | 2.7.10.2 | 0.457 | |
| 2r7b | 253 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.457 | |
| 2w05 | FRT | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.457 | |
| 3kn5 | ANP | Ribosomal protein S6 kinase alpha-5 | 2.7.11.1 | 0.457 | |
| 3qlg | 1N1 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.457 | |
| 3vs7 | KS1 | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.457 | |
| 4e73 | 0NR | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.457 | |
| 4grb | 0XG | Casein kinase II subunit alpha | 2.7.11.1 | 0.457 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.457 | |
| 4ysw | FAD | Xanthine dehydrogenase/oxidase | / | 0.457 | |
| 5cu6 | ATP | Casein kinase II subunit alpha | 2.7.11.1 | 0.457 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.456 | |
| 1rj6 | AZM | Carbonic anhydrase 14 | 4.2.1.1 | 0.456 | |
| 1tqp | ATP | RIO-type serine/threonine-protein kinase Rio2 | 2.7.11.1 | 0.456 | |
| 3ma3 | 01I | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.456 | |
| 3t8o | ATP | Rhodopsin kinase | / | 0.456 | |
| 3vs2 | VSB | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.456 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.456 | |
| 4cd0 | AWJ | ALK tyrosine kinase receptor | 2.7.10.1 | 0.456 | |
| 1eup | ASD | 6-deoxyerythronolide B hydroxylase | / | 0.455 | |
| 1uvr | BI8 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.455 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.455 | |
| 3b2w | 9NH | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.455 | |
| 4ge4 | 0KE | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.455 | |
| 4o70 | 1QK | Bromodomain-containing protein 4 | / | 0.455 | |
| 4rup | H97 | Vitamin D3 receptor A | / | 0.455 | |
| 4wq4 | ATP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.455 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.455 | |
| 5fm7 | ADP | RuvB-like helicase | / | 0.455 | |
| 1g69 | TZP | Thiamine-phosphate synthase | / | 0.454 | |
| 1k6c | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.454 | |
| 1mqb | ANP | Ephrin type-A receptor 2 | 2.7.10.1 | 0.454 | |
| 2ojj | 82A | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.454 | |
| 3elj | GS7 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.454 | |
| 3ls8 | AJZ | Phosphatidylinositol 3-kinase catalytic subunit type 3 | 2.7.1.137 | 0.454 | |
| 3vs5 | VSG | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.454 | |
| 4flh | 14K | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.454 | |
| 4y95 | 746 | Tyrosine-protein kinase | / | 0.454 | |
| 5cwa | 0GA | Anthranilate synthase component 1 | 4.1.3.27 | 0.454 | |
| 1jip | KTN | 6-deoxyerythronolide B hydroxylase | / | 0.453 | |
| 1lny | IMO | Adenylosuccinate synthetase isozyme 1 | / | 0.453 | |
| 1mb9 | ATP | Carboxyethyl-arginine beta-lactam-synthase | 6.3.3.4 | 0.453 | |
| 2b9f | ADP | Mitogen-activated protein kinase FUS3 | 2.7.11.24 | 0.453 | |
| 2b9i | ADP | Mitogen-activated protein kinase FUS3 | 2.7.11.24 | 0.453 | |
| 3czr | 3CZ | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.453 | |
| 4hnc | 0UT | Mandelate racemase | / | 0.453 | |
| 4xx9 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.453 | |
| 1t88 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 2hxl | 422 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.452 | |
| 2yfe | YFE | Peroxisome proliferator-activated receptor gamma | / | 0.452 | |
| 2znn | S44 | Peroxisome proliferator-activated receptor alpha | / | 0.452 | |
| 3ics | COA | Coenzyme A disulfide reductase | / | 0.452 | |
| 3jsk | AHZ | Thiamine thiazole synthase | / | 0.452 | |
| 3tkh | 07S | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.452 | |
| 3tnl | NAD | Shikimate dehydrogenase (NADP(+)) | / | 0.452 | |
| 4c4i | X20 | Dual specificity protein kinase TTK | 2.7.12.1 | 0.452 | |
| 2buj | STU | Serine/threonine-protein kinase 16 | / | 0.451 | |
| 2d8a | NAD | L-threonine 3-dehydrogenase | / | 0.451 | |
| 3h0s | B38 | Acetyl-CoA carboxylase | / | 0.451 | |
| 4euf | NAD | Trans-2-enoyl-CoA reductase [NADH] | / | 0.451 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.451 | |
| 4xx0 | COA | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial | 6.2.1.4 | 0.451 | |
| 1fcb | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.450 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.450 | |
| 1i58 | ACP | Chemotaxis protein CheA | 2.7.13.3 | 0.450 | |
| 1xkk | FMM | Epidermal growth factor receptor | 2.7.10.1 | 0.450 | |
| 2i4p | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.450 | |
| 3at4 | CCK | Casein kinase II subunit alpha | 2.7.11.1 | 0.450 | |
| 3inx | JZC | Heat shock protein HSP 90-alpha | / | 0.450 | |
| 4fjy | FJY | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.450 | |
| 4h50 | NAP | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.450 | |
| 4l42 | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.450 | |
| 1zmc | NAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.449 | |
| 2gr1 | FAD | Ferredoxin reductase | / | 0.449 | |
| 2xvd | AS6 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.449 | |
| 3ba6 | AN2 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.449 | |
| 3hz1 | 42C | Heat shock protein HSP 90-alpha | / | 0.449 | |
| 3mb7 | 14I | Casein kinase II subunit alpha | 2.7.11.1 | 0.449 | |
| 3ute | FAD | UDP-galactopyranose mutase | / | 0.449 | |
| 3uu1 | 14B | Anthranilate phosphoribosyltransferase | / | 0.449 | |
| 4c4g | 7RO | Dual specificity protein kinase TTK | 2.7.12.1 | 0.449 | |
| 4qys | PLR | Tryptophan synthase beta chain 2 | 4.2.1.20 | 0.449 | |
| 5ack | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.449 | |
| 1ie4 | T44 | Transthyretin | / | 0.448 | |
| 1ihx | SND | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.448 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.448 | |
| 2hma | SAM | tRNA-specific 2-thiouridylase MnmA | / | 0.448 | |
| 2hy0 | 306 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.448 | |
| 2hy8 | 1ST | Serine/threonine-protein kinase PAK 1 | 2.7.11.1 | 0.448 | |
| 2izs | BRQ | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.448 | |
| 2xbj | XBJ | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.448 | |
| 2y46 | MIV | Mycinamicin IV hydroxylase/epoxidase | / | 0.448 | |
| 3rpv | 26Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
| 3slk | NDP | Polyketide synthase extender module 2 | / | 0.448 | |
| 3v9y | 24L | Peroxisome proliferator-activated receptor gamma | / | 0.448 | |
| 3vs0 | VS0 | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.448 | |
| 4j97 | ACP | Fibroblast growth factor receptor 2 | / | 0.448 | |
| 1d7l | RFL | p-hydroxybenzoate hydroxylase | / | 0.447 | |
| 1iep | STI | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.447 | |
| 1oiy | N41 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 1zar | ADP | RIO-type serine/threonine-protein kinase Rio2 | 2.7.11.1 | 0.447 | |
| 2itu | ITQ | Epidermal growth factor receptor | 2.7.10.1 | 0.447 | |
| 2pob | GW4 | Peroxisome proliferator-activated receptor gamma | / | 0.447 | |
| 3nun | JMZ | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.447 | |
| 3pxy | JWS | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 4hfr | 14M | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.447 | |
| 1j1c | ADP | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.446 | |
| 1og5 | SWF | Cytochrome P450 2C9 | / | 0.446 | |
| 1ppj | ANY | Cytochrome b | / | 0.446 | |
| 1q3q | ANP | Thermosome subunit alpha | / | 0.446 | |
| 1t1s | CBQ | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.446 | |
| 1ztf | XYA | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.446 | |
| 3sp9 | IL2 | Peroxisome proliferator-activated receptor delta | / | 0.446 | |
| 4rnh | C2E | Motility regulator | / | 0.446 | |
| 1kl2 | FON | Serine hydroxymethyltransferase | / | 0.445 | |
| 1pnv | TYD | dTDP-epi-vancosaminyltransferase | 2.4.1.311 | 0.445 | |
| 1rby | KEU | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.445 | |
| 1sn5 | T3 | Transthyretin | / | 0.445 | |
| 2cke | IQU | Death-associated protein kinase 2 | / | 0.445 | |
| 2jko | BIJ | Focal adhesion kinase 1 | 2.7.10.2 | 0.445 | |
| 2q59 | 240 | Peroxisome proliferator-activated receptor gamma | / | 0.445 | |
| 2xck | MH4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.445 | |
| 3q4z | ANP | Serine/threonine-protein kinase PAK 1 | 2.7.11.1 | 0.445 | |
| 3qk0 | QK0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.445 | |
| 3zw9 | NAD | Peroxisomal bifunctional enzyme | 1.1.1.35 | 0.445 | |
| 4bkz | 1WS | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.445 | |
| 4bl1 | ANP | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.445 | |
| 4c57 | FEF | Cyclin-G-associated kinase | 2.7.11.1 | 0.445 | |
| 4ftj | H8K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.445 | |
| 4ike | ADP | Adenylate kinase | / | 0.445 | |
| 4kgm | ATP | Uncharacterized protein | / | 0.445 | |
| 4otp | ADP | Serine/threonine-protein kinase RIO1 | 2.7.11.1 | 0.445 | |
| 4qa2 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.445 | |
| 4xuh | SFI | Peroxisome proliferator-activated receptor gamma | / | 0.445 | |
| 5dos | ATP | Aurora kinase A | 2.7.11.1 | 0.445 | |
| 1byg | STU | Tyrosine-protein kinase CSK | / | 0.444 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.444 | |
| 1om1 | IQA | Casein kinase II subunit alpha | 2.7.11.1 | 0.444 | |
| 1uu3 | LY4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.444 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.444 | |
| 2aqh | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.444 | |
| 2xtz | GSP | Guanine nucleotide-binding protein alpha-1 subunit | / | 0.444 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.444 | |
| 3vew | ADP | nebramycin 5' synthase | 6.1.2.2 | 0.444 | |
| 4f9m | FCM | Peroxisome proliferator-activated receptor gamma | / | 0.444 | |
| 4h6r | FDA | Proline dehydrogenase | / | 0.444 | |
| 4yhj | AN2 | G protein-coupled receptor kinase 4 | 2.7.11.16 | 0.444 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.444 | |
| 1di8 | DTQ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.443 | |
| 1v9a | SAH | Uncharacterized protein | / | 0.443 | |
| 2c27 | MA8 | Mycothiol acetyltransferase | 2.3.1.189 | 0.443 | |
| 2itn | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.443 | |
| 3hxb | BD5 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.443 | |
| 3lfc | Z86 | Mitogen-activated protein kinase 14 | / | 0.443 | |
| 3orz | BI4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.443 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.443 | |
| 3zon | IK1 | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.443 | |
| 4a28 | ADP | Kinesin-like protein KIF11 | / | 0.443 | |
| 4bi0 | Z0W | Dual specificity protein kinase TTK | 2.7.12.1 | 0.443 | |
| 4g17 | 0VN | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.443 | |
| 4qmx | H8H | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.443 | |
| 4xiw | AZM | Carbonic anhydrase, alpha type | / | 0.443 | |
| 4zhq | ACP | Tubulin tyrosine ligase | / | 0.443 | |
| 4zoh | FAD | Putative oxidoreductase FAD-binding subunit | / | 0.443 | |
| 1c70 | L75 | Protease | / | 0.442 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.442 | |
| 1iwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 1k6p | XN3 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 1qr6 | NAD | NAD-dependent malic enzyme, mitochondrial | 1.1.1.38 | 0.442 | |
| 1tqm | ANP | RIO-type serine/threonine-protein kinase Rio2 | 2.7.11.1 | 0.442 | |
| 1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.442 | |
| 1zrz | BI1 | Protein kinase C iota type | 2.7.11.13 | 0.442 | |
| 3cgc | COA | Coenzyme A disulfide reductase | / | 0.442 | |
| 3csd | EMO | Putative ketoacyl reductase | 1.3.1 | 0.442 | |
| 3cty | FAD | Probable thioredoxin reductase | / | 0.442 | |
| 3ft8 | MOJ | Heat shock protein HSP 90-alpha | / | 0.442 | |
| 3iel | U5P | Ribonuclease TTHA0252 | 3.1 | 0.442 | |
| 3l63 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 3ogq | AB1 | Pol polyprotein | / | 0.442 | |
| 3tri | NAP | Pyrroline-5-carboxylate reductase | / | 0.442 | |
| 3tti | KBI | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.442 | |
| 3u9e | COA | Lmo1369 protein | / | 0.442 | |
| 3zhq | TPP | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.442 | |
| 4anu | EM7 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.442 | |
| 4btk | DTQ | Tau-tubulin kinase 1 | 2.7.11.1 | 0.442 | |
| 4hfm | NAP | 2-alkenal reductase (NADP(+)-dependent) | / | 0.442 | |
| 4jaz | STL | Peroxisome proliferator-activated receptor gamma | / | 0.442 | |
| 4jia | 1K3 | Tyrosine-protein kinase JAK2 | / | 0.442 | |
| 4l7s | G7K | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.442 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.442 | |
| 4o2b | LOC | Tubulin beta-2B chain | / | 0.442 | |
| 1dxo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.441 | |
| 1ojt | FAD | Dihydrolipoyl dehydrogenase | / | 0.441 | |
| 1qcf | PP1 | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.441 | |
| 2oh0 | 2PY | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.441 | |
| 3a3b | RBF | Lumazine protein | / | 0.441 | |
| 3axw | TID | Casein kinase II subunit alpha | 2.7.11.1 | 0.441 | |
| 3fwf | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 3iw6 | PP0 | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 3q9x | EMO | Casein kinase II subunit alpha | 2.7.11.1 | 0.441 | |
| 3qd4 | 3Q6 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.441 | |
| 3unk | 0BY | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 3vjh | J35 | Peroxisome proliferator-activated receptor gamma | / | 0.441 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.441 | |
| 4fad | 0TB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.441 | |
| 4iwo | 1H4 | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.441 | |
| 4nxw | ADP | Mitochondrial dynamics protein MID51 | / | 0.441 | |
| 4uym | VOR | 14-alpha sterol demethylase Cyp51B | / | 0.441 | |
| 4xwt | U5P | Ribonuclease J | / | 0.441 | |
| 1oi9 | N20 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 1phe | PIY | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 1rfv | ADP | Pyridoxal kinase | 2.7.1.35 | 0.440 | |
| 1t87 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 1uu8 | BI1 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.440 | |
| 2has | C3O | Vitamin D3 receptor | / | 0.440 | |
| 2i5b | ADP | Pyridoxine kinase | / | 0.440 | |
| 2q61 | SF1 | Peroxisome proliferator-activated receptor gamma | / | 0.440 | |
| 2wot | ZZG | TGF-beta receptor type-1 | 2.7.11.30 | 0.440 | |
| 3cd5 | 7HI | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.34 | 0.440 | |
| 3il1 | B5D | Glutamate receptor 2 | / | 0.440 | |
| 3nal | DBK | Calcium-transporting ATPase | / | 0.440 | |
| 3uvq | FS8 | Mitogen-activated protein kinase 14 | / | 0.440 | |
| 4a4v | YFD | Peroxisome proliferator-activated receptor gamma | / | 0.440 | |
| 4anw | O92 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 4eny | J19 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.440 | |
| 4f4p | 0SB | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.440 | |
| 4g09 | 0VD | Histidinol dehydrogenase | / | 0.440 | |
| 4gu9 | 4GU | Focal adhesion kinase 1 | 2.7.10.2 | 0.440 | |
| 4in4 | 4ID | Kelch-like ECH-associated protein 1 | / | 0.440 | |
| 4jk4 | DIU | Serum albumin | / | 0.440 | |
| 4oag | ADP | Mitochondrial dynamics protein MID51 | / | 0.440 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.440 |