sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3fnu | 006 | HAP protein |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3fnu | 006 | HAP protein | / | 1.000 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.516 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.514 | |
| 3oq1 | 3OQ | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.507 | |
| 3gie | ACP | Sensor histidine kinase DesK | 2.7.13.3 | 0.500 | |
| 3up3 | XCA | aceDAF-12 | / | 0.500 | |
| 3h0a | 9RA | Retinoic acid receptor RXR-alpha | / | 0.498 | |
| 1xu9 | CPS | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.497 | |
| 3p9t | TCL | Repressor | / | 0.497 | |
| 5uvi | ZMA | Adenosine receptor A2a | / | 0.491 | |
| 3qm4 | PN0 | Cytochrome P450 2D6 | / | 0.489 | |
| 4fhi | 0S4 | Vitamin D3 receptor A | / | 0.489 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.488 | |
| 1x2h | LPA | Lipoate-protein ligase A | 6.3.1.20 | 0.488 | |
| 3qrw | NDP | Putative ketoacyl reductase | 1.3.1 | 0.488 | |
| 1v35 | NAI | Enoyl-ACP reductase | / | 0.487 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.486 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.484 | |
| 2hb8 | MVD | Vitamin D3 receptor | / | 0.484 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.484 | |
| 2zb4 | 5OP | Prostaglandin reductase 2 | 1.3.1.48 | 0.483 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.483 | |
| 4b1f | KRH | Glutamate racemase | / | 0.483 | |
| 4eil | FOL | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.482 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.482 | |
| 2xk4 | OL2 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.480 | |
| 3byz | H11 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.480 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.480 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.480 | |
| 1e7a | PFL | Serum albumin | / | 0.479 | |
| 1fel | FEN | Retinol-binding protein 4 | / | 0.479 | |
| 2qo5 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.479 | |
| 4i9i | 1DY | Tankyrase-1 | 2.4.2.30 | 0.479 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.478 | |
| 2bkt | RPF | Renin | 3.4.23.15 | 0.478 | |
| 2jn3 | JN3 | Fatty acid-binding protein, liver | / | 0.478 | |
| 2xk8 | 5R1 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.478 | |
| 4m6j | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.477 | |
| 4o1m | NAD | Enoyl-acyl carrier reductase | / | 0.477 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.476 | |
| 1og5 | SWF | Cytochrome P450 2C9 | / | 0.476 | |
| 1v7a | FRC | Adenosine deaminase | 3.5.4.4 | 0.476 | |
| 2bns | MST | Reaction center protein L chain | / | 0.476 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.476 | |
| 4mvh | 2F5 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.476 | |
| 1dr5 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.475 | |
| 4ky4 | 04J | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.475 | |
| 1ao8 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.474 | |
| 3d75 | NBB | Pheromone-binding protein ASP1 | / | 0.474 | |
| 3nj0 | PYV | Abscisic acid receptor PYL2 | / | 0.474 | |
| 3s3v | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.474 | |
| 1osv | CHC | Bile acid receptor | / | 0.473 | |
| 2fr0 | NDP | 6-deoxyerythronolide-B synthase EryA1, modules 1 and 2 | / | 0.473 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.473 | |
| 3eml | ZMA | Adenosine receptor A2a | / | 0.473 | |
| 1n4h | REA | Nuclear receptor ROR-beta | / | 0.472 | |
| 3gyt | DL4 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.472 | |
| 3lak | KR1 | Gag-Pol polyprotein | 2.7.7.49 | 0.472 | |
| 3ua5 | 06X | Cytochrome P450 2B6 | 1.14.13 | 0.472 | |
| 3vtc | TK3 | Vitamin D3 receptor | / | 0.472 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.472 | |
| 5k2b | ZMA | Adenosine receptor A2a | / | 0.472 | |
| 2agv | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.471 | |
| 2dhf | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.471 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.471 | |
| 2op1 | 8PC | Enoyl-ACP reductase | / | 0.471 | |
| 3dol | GWI | Pol protein | / | 0.471 | |
| 3hxb | BD5 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.471 | |
| 3nrr | D16 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.471 | |
| 3bfa | 9OD | Odorant binding protein ASP1 | / | 0.470 | |
| 4ia1 | BIV | Vitamin D3 receptor A | / | 0.470 | |
| 4lb2 | DM5 | Serum albumin | / | 0.470 | |
| 1f28 | F89 | Thymidylate synthase | 2.1.1.45 | 0.469 | |
| 1txi | TX5 | Vitamin D3 receptor | / | 0.469 | |
| 2ilt | NN1 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.469 | |
| 2xvv | 9DN | Serum albumin | / | 0.469 | |
| 3itu | IBM | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.469 | |
| 3qpp | PFW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.469 | |
| 3w8w | FAD | Putative FAD-dependent oxygenase EncM | / | 0.469 | |
| 4iaq | 2GM | 5-hydroxytryptamine receptor 1B | / | 0.469 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.469 | |
| 1ml6 | GBX | Glutathione S-transferase A2 | 2.5.1.18 | 0.468 | |
| 1o5r | FR9 | Adenosine deaminase | 3.5.4.4 | 0.468 | |
| 1rkg | VD1 | Vitamin D3 receptor | / | 0.468 | |
| 2bf7 | HBI | Pteridine reductase 1 | 1.5.1.33 | 0.468 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.468 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.468 | |
| 3c1x | CKK | Hepatocyte growth factor receptor | 2.7.10.1 | 0.468 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.468 | |
| 4muw | 2F4 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.468 | |
| 3k1w | BFX | Renin | 3.4.23.15 | 0.467 | |
| 3w5t | LHP | Vitamin D3 receptor | / | 0.467 | |
| 5ai5 | BSU | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.467 | |
| 3rfm | CFF | Adenosine receptor A2a | / | 0.467 | |
| 1s1v | TNK | Gag-Pol polyprotein | 2.7.7.49 | 0.466 | |
| 1upw | 444 | Oxysterols receptor LXR-beta | / | 0.466 | |
| 3bej | MUF | Bile acid receptor | / | 0.466 | |
| 3vt6 | 5YI | Vitamin D3 receptor | / | 0.466 | |
| 4euf | NAD | Trans-2-enoyl-CoA reductase [NADH] | / | 0.466 | |
| 1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
| 1ohk | COP | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
| 1rd4 | L08 | Integrin alpha-L | / | 0.465 | |
| 2b01 | TUD | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.465 | |
| 2yiu | SMA | Cytochrome b | / | 0.465 | |
| 3oad | LPO | Renin | 3.4.23.15 | 0.465 | |
| 3oez | STI | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.465 | |
| 3u4c | NDP | NADPH-dependent reductase BacG | / | 0.465 | |
| 4bb6 | HD1 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.465 | |
| 4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.465 | |
| 1d3h | A26 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.464 | |
| 1qkn | RAL | Estrogen receptor beta | / | 0.464 | |
| 4iui | 1GQ | Estrogen receptor | / | 0.464 | |
| 1m52 | P17 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.463 | |
| 1p8d | CO1 | Oxysterols receptor LXR-beta | / | 0.463 | |
| 1tw4 | CHD | Fatty acid-binding protein, liver | / | 0.463 | |
| 1uml | FR4 | Adenosine deaminase | 3.5.4.4 | 0.463 | |
| 1w22 | NHB | Histone deacetylase 8 | 3.5.1.98 | 0.463 | |
| 1zkl | IBM | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | 3.1.4.53 | 0.463 | |
| 2b36 | 5PP | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.463 | |
| 2har | OCC | Vitamin D3 receptor | / | 0.463 | |
| 2hb7 | O1C | Vitamin D3 receptor | / | 0.463 | |
| 2xvw | 9NR | Serum albumin | / | 0.463 | |
| 3dya | PZL | Gag-Pol polyprotein | 2.7.7.49 | 0.463 | |
| 3gmd | 2M3 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.463 | |
| 3irn | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.463 | |
| 3qlz | QLZ | Uncharacterized protein | / | 0.463 | |
| 4ejg | NCT | Cytochrome P450 2A13 | 1.14.14.1 | 0.463 | |
| 5iub | CLR | Adenosine receptor A2a | / | 0.463 | |
| 3ar5 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.462 | |
| 3i0r | RT3 | Gag-Pol polyprotein | 2.7.7.49 | 0.462 | |
| 3is9 | AC7 | Gag-Pol polyprotein | 2.7.7.49 | 0.462 | |
| 3meg | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.462 | |
| 4e37 | NDP | Catalase | 1.11.1.6 | 0.462 | |
| 4g2h | 0VQ | Vitamin D3 receptor A | / | 0.462 | |
| 4h96 | 14Q | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 5k2d | ZMA | Adenosine receptor A2a | / | 0.462 | |
| 1err | RAL | Estrogen receptor | / | 0.461 | |
| 1rti | HEF | Gag-Pol polyprotein | 2.7.7.49 | 0.461 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 1x7h | NDP | Putative ketoacyl reductase | 1.3.1 | 0.461 | |
| 1yho | TRR | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.461 | |
| 3d80 | Q22 | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 3v2u | ATP | Protein GAL3 | / | 0.461 | |
| 4g1y | 0VO | Vitamin D3 receptor A | / | 0.461 | |
| 4kbn | 25U | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 1uhl | MEI | Retinoic acid receptor RXR-beta | / | 0.460 | |
| 3mee | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.460 | |
| 3n0h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 3reo | EUG | (Iso)eugenol O-methyltransferase | 2.1.1.146 | 0.460 | |
| 1db1 | VDX | Vitamin D3 receptor | / | 0.459 | |
| 1h35 | R01 | Squalene--hopene cyclase | 4.2.1.129 | 0.459 | |
| 1q5m | NDP | Prostaglandin-E(2) 9-reductase | 1.1.1.189 | 0.459 | |
| 1rkh | VD2 | Vitamin D3 receptor | / | 0.459 | |
| 2acw | UPG | Glycosyltransferase | / | 0.459 | |
| 3a4o | STU | Tyrosine-protein kinase Lyn | 2.7.10.2 | 0.459 | |
| 3bfb | 9OD | Pheromone-binding protein ASP1 | / | 0.459 | |
| 3ezp | B3N | Histone deacetylase 8 | 3.5.1.98 | 0.459 | |
| 3l8s | BFF | Mitogen-activated protein kinase 14 | / | 0.459 | |
| 3td8 | D2R | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.459 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.459 | |
| 4jda | A9S | Abscisic acid receptor PYL3 | / | 0.459 | |
| 1ai9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 2cl5 | BIE | Catechol O-methyltransferase | 2.1.1.6 | 0.458 | |
| 2h2q | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.458 | |
| 2h94 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.458 | |
| 3dga | RJ1 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.458 | |
| 3g70 | A5T | Renin | 3.4.23.15 | 0.458 | |
| 3gph | OID | Cytochrome P450 2E1 | 1.14.13 | 0.458 | |
| 3hbb | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.458 | |
| 3nxx | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 3srw | Q27 | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 3vt4 | 5YI | Vitamin D3 receptor | / | 0.458 | |
| 4a4o | 664 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.458 | |
| 4c1i | EH9 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.458 | |
| 4cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 4equ | G6I | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.458 | |
| 4h95 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 4hf4 | 15H | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.458 | |
| 1e3v | DXC | Steroid Delta-isomerase | 5.3.3.1 | 0.457 | |
| 1ia4 | TQ6 | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 1j3j | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.457 | |
| 1n83 | CLR | Nuclear receptor ROR-alpha | / | 0.457 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 1rt2 | TNK | Gag-Pol polyprotein | 2.7.7.49 | 0.457 | |
| 1rx6 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 1s19 | MC9 | Vitamin D3 receptor | / | 0.457 | |
| 2bnp | MST | Reaction center protein L chain | / | 0.457 | |
| 2ibz | SMA | Cytochrome b | / | 0.457 | |
| 2ydv | NEC | Adenosine receptor A2a | / | 0.457 | |
| 3di6 | PDZ | Gag-Pol polyprotein | 2.7.7.49 | 0.457 | |
| 3hcr | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.457 | |
| 3lam | KRP | Gag-Pol polyprotein | 2.7.7.49 | 0.457 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.457 | |
| 4g21 | 0VP | Vitamin D3 receptor A | / | 0.457 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.457 | |
| 4mfb | 29T | Gag-Pol polyprotein | 2.7.7.49 | 0.457 | |
| 5dq8 | FLF | Transcriptional enhancer factor TEF-4 | / | 0.457 | |
| 5iu8 | 6DZ | Adenosine receptor A2a | / | 0.457 | |
| 3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.457 | |
| 1ezf | IN0 | Squalene synthase | 2.5.1.21 | 0.456 | |
| 1pkf | EPD | Epothilone C/D epoxidase | 1.14 | 0.456 | |
| 1rk3 | VDX | Vitamin D3 receptor | / | 0.456 | |
| 2hc4 | VDX | Vitamin D3 receptor A | / | 0.456 | |
| 2vss | ACO | Hydroxycinnamoyl-CoA hydratase-lyase | 4.1.2.41 | 0.456 | |
| 3c6t | M14 | Gag-Pol polyprotein | 2.7.7.49 | 0.456 | |
| 3fco | IIG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.456 | |
| 3qly | 55V | Uncharacterized protein | / | 0.456 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.456 | |
| 3vtb | TKA | Vitamin D3 receptor | / | 0.456 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 4fjz | 4FJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.456 | |
| 4nb6 | 444 | Nuclear receptor ROR-gamma | / | 0.456 | |
| 4qa0 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.456 | |
| 5ab7 | MLC | Nonspecific lipid-transfer protein, putative | / | 0.456 | |
| 1ry0 | PG2 | Aldo-keto reductase family 1 member C3 | / | 0.455 | |
| 1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.455 | |
| 2fs4 | PZ1 | Renin | 3.4.23.15 | 0.455 | |
| 2igy | A2T | Plasmepsin 2 | / | 0.455 | |
| 3w0a | DS5 | Vitamin D3 receptor | / | 0.455 | |
| 4dk5 | 0KO | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.455 | |
| 4h97 | 53S | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 1aoe | GW3 | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 1el4 | CTZ | Obelin | / | 0.454 | |
| 1ezv | SMA | Cytochrome b | / | 0.454 | |
| 1r9o | FLP | Cytochrome P450 2C9 | / | 0.454 | |
| 1t47 | NTD | 4-hydroxyphenylpyruvate dioxygenase | 1.13.11.27 | 0.454 | |
| 2fsz | OHT | Estrogen receptor beta | / | 0.454 | |
| 2fzi | DH3 | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.454 | |
| 3ey4 | 352 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.454 | |
| 3gcq | 1BU | Mitogen-activated protein kinase 14 | / | 0.454 | |
| 4eil | CB3 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.454 | |
| 4htx | 19F | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.454 | |
| 4li7 | 1XP | Tankyrase-1 | 2.4.2.30 | 0.454 | |
| 4mm7 | 29J | Na(+):neurotransmitter symporter (Snf family) | / | 0.454 | |
| 5k2c | ZMA | Adenosine receptor A2a | / | 0.454 | |
| 5k2a | ZMA | Adenosine receptor A2a | / | 0.454 | |
| 5jtb | ZMA | Adenosine receptor A2a | / | 0.454 | |
| 1dkf | BMS | Retinoic acid receptor alpha | / | 0.453 | |
| 1dr2 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.453 | |
| 1qxl | FR8 | Adenosine deaminase | 3.5.4.4 | 0.453 | |
| 1v79 | FR7 | Adenosine deaminase | 3.5.4.4 | 0.453 | |
| 2hnz | PC0 | Gag-Pol polyprotein | 2.7.7.49 | 0.453 | |
| 2on6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.453 | |
| 3e01 | PZ2 | Gag-Pol polyprotein | 2.7.7.49 | 0.453 | |
| 3eem | 53V | Uncharacterized protein | / | 0.453 | |
| 3ns2 | PYV | Abscisic acid receptor PYL2 | / | 0.453 | |
| 3pz2 | 3PZ | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.453 | |
| 3v1m | HPK | 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase | 3.7.1.8 | 0.453 | |
| 3v1s | 0LH | Strictosidine synthase | 4.3.3.2 | 0.453 | |
| 4dsc | A8S | Abscisic acid receptor PYL3 | / | 0.453 | |
| 4i7f | NVE | Gag-Pol polyprotein | 2.7.7.49 | 0.453 | |
| 5hbr | COA | Acyl-CoA synthetase (NDP forming) | / | 0.453 | |
| 5iu4 | ZMA | Adenosine receptor A2a | / | 0.453 | |
| 1dhf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1hvy | D16 | Thymidylate synthase | 2.1.1.45 | 0.452 | |
| 1iyz | NDP | Probable quinone oxidoreductase | / | 0.452 | |
| 1ot7 | CHC | Bile acid receptor | / | 0.452 | |
| 1so2 | 666 | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.452 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 2wsi | FAD | FAD synthase | 2.7.7.2 | 0.452 | |
| 3aiq | HBO | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1b, chloroplastic | 3.2.1.182 | 0.452 | |
| 3gyu | DL7 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.452 | |
| 3qls | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 3qpn | PFK | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.452 | |
| 3tda | PN0 | Cytochrome P450 2D6 | / | 0.452 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.452 | |
| 4g1d | 0VK | Vitamin D3 receptor A | / | 0.452 | |
| 1rx8 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1s3v | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 2w3v | TOP | Dihydrofolate reductase | / | 0.451 | |
| 3g49 | 3G4 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.451 | |
| 3h1j | SMA | Cytochrome b | / | 0.451 | |
| 3inv | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.451 | |
| 3lan | KBT | Gag-Pol polyprotein | 2.7.7.49 | 0.451 | |
| 4a84 | DXC | Major pollen allergen Bet v 1-A | / | 0.451 | |
| 4a87 | NAR | Major pollen allergen Bet v 1-A | / | 0.451 | |
| 1o6q | R17 | Squalene--hopene cyclase | 4.2.1.129 | 0.450 | |
| 1z4i | UMP | 5'(3')-deoxyribonucleotidase, mitochondrial | 3.1.3 | 0.450 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.450 | |
| 3dg8 | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.450 | |
| 3fnh | JPJ | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.450 | |
| 4gtv | 7TR | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.450 | |
| 4k5y | 1Q5 | Corticotropin-releasing factor receptor 1 | / | 0.450 | |
| 1equ | EQI | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.449 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.449 | |
| 1ia2 | TQ4 | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1kt3 | RTL | Retinol-binding protein 4 | / | 0.449 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 1xon | PIL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.449 | |
| 1y2d | 4DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.449 | |
| 2gdz | NAD | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | 1.1.1.141 | 0.449 | |
| 2has | C3O | Vitamin D3 receptor | / | 0.449 | |
| 2ol4 | JPN | Enoyl-ACP reductase | / | 0.449 | |
| 2wey | EV1 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.449 | |
| 2xk7 | 30E | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.449 | |
| 3cxh | SMA | Cytochrome b | / | 0.449 | |
| 3d3e | D3E | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.449 | |
| 3h18 | PMS | Esterase/lipase | / | 0.449 | |
| 3ipq | 965 | Oxysterols receptor LXR-alpha | / | 0.449 | |
| 3irm | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.449 | |
| 3kpz | ZNE | Vitamin D3 receptor | / | 0.449 | |
| 3w0j | T08 | Vitamin D3 receptor | / | 0.449 | |
| 4ite | TEY | Vitamin D3 receptor | / | 0.449 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.448 | |
| 1ly4 | COQ | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1s0z | EB1 | Vitamin D3 receptor | / | 0.448 | |
| 1zid | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.448 | |
| 2hw2 | RFP | Rifampin ADP-ribosyl transferase | / | 0.448 | |
| 2igx | A1T | Plasmepsin 2 | / | 0.448 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.448 | |
| 3c0i | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.448 | |
| 3eig | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 3g5s | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.448 | |
| 3hx3 | RET | Retinaldehyde-binding protein 1 | / | 0.448 | |
| 3k47 | D09 | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 4g20 | 484 | Vitamin D3 receptor A | / | 0.448 | |
| 4m6l | 21V | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 4pnm | NU1 | Tankyrase-2 | 2.4.2.30 | 0.448 | |
| 1enz | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.447 | |
| 1ie8 | KH1 | Vitamin D3 receptor | / | 0.447 | |
| 1opb | RET | Retinol-binding protein 2 | / | 0.447 | |
| 1rx1 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 2oax | SNL | Mineralocorticoid receptor | / | 0.447 | |
| 2ovy | PFJ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.447 | |
| 2p1u | 4TN | Retinoic acid receptor RXR-alpha | / | 0.447 | |
| 2z2w | 770 | Wee1-like protein kinase | 2.7.10.2 | 0.447 | |
| 2z7g | EH9 | Adenosine deaminase | 3.5.4.4 | 0.447 | |
| 3ipt | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.447 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.447 | |
| 3njo | PYV | Abscisic acid receptor PYR1 | / | 0.447 | |
| 3sgv | 2BJ | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.447 | |
| 3tm4 | SAM | Uncharacterized protein | / | 0.447 | |
| 4a6e | ASE | Acetylserotonin O-methyltransferase | 2.1.1.4 | 0.447 | |
| 4i2p | G73 | Gag-Pol polyprotein | 2.7.7.49 | 0.447 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 1eio | GCH | Gastrotropin | / | 0.446 | |
| 1ep4 | S11 | Gag-Pol polyprotein | 2.7.7.49 | 0.446 | |
| 1hpz | AAP | Gag-Pol polyprotein | 2.7.7.49 | 0.446 | |
| 1iiu | RTL | Retinol-binding protein 4 | / | 0.446 | |
| 1n4p | CYS_VAL_ILE_LEU_GER | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.446 | |
| 1r2j | FAD | FkbI | / | 0.446 | |
| 1rdt | L79 | Retinoic acid receptor RXR-alpha | / | 0.446 | |
| 2a19 | ANP | Interferon-induced, double-stranded RNA-activated protein kinase | 2.7.11.1 | 0.446 | |
| 2blb | CP7 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.446 | |
| 2fzw | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.446 | |
| 2ilu | NDP | Lactaldehyde dehydrogenase | 1.2.1.22 | 0.446 | |
| 2j9g | ADP | Biotin carboxylase | 6.3.4.14 | 0.446 | |
| 2nxe | SAM | Ribosomal protein L11 methyltransferase | 2.1.1 | 0.446 | |
| 2zlc | VDX | Vitamin D3 receptor | / | 0.446 | |
| 3aiv | HBO | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase, chloroplastic | 3.2.1.182 | 0.446 | |
| 3ar6 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.446 | |
| 3ghv | GHC | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 3up0 | D7S | aceDAF-12 | / | 0.446 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.446 | |
| 4ajd | F04 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.446 | |
| 4bb5 | HD2 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.446 | |
| 4h4o | 506 | Gag-Pol polyprotein | 2.7.7.49 | 0.446 | |
| 4qoe | FAD | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.446 | |
| 1j0b | 5PA | Putative 1-aminocyclopropane-1-carboxylate deaminase | 3.5.99.7 | 0.445 | |
| 1jtu | LYB | Thymidylate synthase | / | 0.445 | |
| 1s0x | C3S | Nuclear receptor ROR-alpha | / | 0.445 | |
| 1soj | IBM | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.445 | |
| 2cig | 1DG | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 2pnc | CLU | Primary amine oxidase, liver isozyme | / | 0.445 | |
| 2xui | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 2ze2 | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.445 | |
| 3dfr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 3n6u | TSU | HTH-type transcriptional regulator TsaR | / | 0.445 | |
| 3w0g | W07 | Vitamin D3 receptor | / | 0.445 | |
| 4bch | T7Z | Cyclin-dependent kinase 9 | 2.7.11.22 | 0.445 | |
| 4bii | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.445 | |
| 4ejh | 0QA | Cytochrome P450 2A13 | 1.14.14.1 | 0.445 | |
| 4l0q | NAD | Alcohol dehydrogenase class-3 | / | 0.445 | |
| 1eny | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.444 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1j3k | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.444 | |
| 1p0p | BCH | Cholinesterase | 3.1.1.8 | 0.444 | |
| 1rjk | VDZ | Vitamin D3 receptor | / | 0.444 | |
| 1uxn | NAP | NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase | / | 0.444 | |
| 2f38 | 15M | Aldo-keto reductase family 1 member C3 | / | 0.444 | |
| 2o4r | VD5 | Vitamin D3 receptor | / | 0.444 | |
| 2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.444 | |
| 2pnu | ENM | Androgen receptor | / | 0.444 | |
| 2rf2 | MRX | Gag-Pol polyprotein | 2.7.7.49 | 0.444 | |
| 3bzu | A21 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.444 | |
| 3kjs | DQ1 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.444 | |
| 3lfe | Z84 | Mitogen-activated protein kinase 14 | / | 0.444 | |
| 4ddl | 0JQ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.444 | |
| 4hhz | 15S | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.444 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.444 | |
| 4jvn | YUG | Estrogen sulfotransferase | 2.8.2.4 | 0.444 | |
| 5ecc | NAP | Dehydrofolate reductase type I | / | 0.444 | |
| 4ea3 | 0NN | Nociceptin receptor | / | 0.444 | |
| 1tbb | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.443 | |
| 1tl7 | FOK | Adenylate cyclase type 2 | / | 0.443 | |
| 1tl7 | FOK | Adenylate cyclase type 5 | / | 0.443 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.443 | |
| 1xdu | SFG | Aclacinomycin 10-hydroxylase RdmB | 4.1.1 | 0.443 | |
| 2bxm | IMN | Serum albumin | / | 0.443 | |
| 2fpc | SCG | Strictosidine synthase | 4.3.3.2 | 0.443 | |
| 2qjp | SMA | Cytochrome b | / | 0.443 | |
| 2xkf | BX1 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.443 | |
| 3b9l | AZZ | Serum albumin | / | 0.443 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.443 | |
| 3d74 | NBB | Pheromone-binding protein ASP1 | / | 0.443 | |
| 3eel | 53T | Uncharacterized protein | / | 0.443 | |
| 3l70 | JZV | Cytochrome b | / | 0.443 | |
| 3qls | 55V | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 3sl6 | JN8 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.443 | |
| 3vg9 | ZMA | Adenosine receptor A2a | / | 0.443 | |
| 4dvq | 1CA | Cytochrome P450 11B2, mitochondrial | 1.14.15.4 | 0.443 | |
| 4fhh | 0U3 | Vitamin D3 receptor A | / | 0.443 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.443 | |
| 4n1f | CZH | Obelin | / | 0.443 | |
| 4phl | PIL | Phosphodiesterase | / | 0.443 | |
| 4qa2 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.443 | |
| 4wa9 | AXI | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.443 | |
| 5akk | 1P8 | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.443 | |
| 3uzc | T4E | Adenosine receptor A2a | / | 0.443 | |
| 1fk9 | EFZ | Gag-Pol polyprotein | 2.7.7.49 | 0.442 | |
| 1g3m | PCQ | Estrogen sulfotransferase | 2.8.2.4 | 0.442 | |
| 1ndz | FR5 | Adenosine deaminase | 3.5.4.4 | 0.442 | |
| 1tsd | F89 | Thymidylate synthase | / | 0.442 | |
| 1uom | PTI | Estrogen receptor | / | 0.442 | |
| 1uy7 | PU4 | Heat shock protein HSP 90-alpha | / | 0.442 | |
| 1vrw | NAI | Enoyl-ACP reductase | / | 0.442 | |
| 1yqd | NAP | Sinapyl alcohol dehydrogenase | / | 0.442 | |
| 1zdw | FLV | Prenyltransferase | / | 0.442 | |
| 2azy | CHD | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.442 | |
| 2bxo | OPB | Serum albumin | / | 0.442 | |
| 2o4j | VD4 | Vitamin D3 receptor | / | 0.442 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 2ynf | WHU | Gag-Pol polyprotein | 2.7.7.49 | 0.442 | |
| 3cse | N22 | Uncharacterized protein | / | 0.442 | |
| 3g6z | A7T | Renin | 3.4.23.15 | 0.442 | |
| 3s79 | ASD | Aromatase | 1.14.14.14 | 0.442 | |
| 3w0c | 6DS | Vitamin D3 receptor | / | 0.442 | |
| 3wsb | RWZ | Farnesyltransferase, putative | / | 0.442 | |
| 4eev | L1X | Hepatocyte growth factor receptor | 2.7.10.1 | 0.442 | |
| 4hfr | 14M | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.442 | |
| 1diu | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1m7a | MQU | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 1y2k | 7DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.441 | |
| 1ysx | 4EB | Serum albumin | / | 0.441 | |
| 2o8h | 227 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.441 | |
| 2vna | NAP | Prostaglandin reductase 2 | 1.3.1.48 | 0.441 | |
| 2wsa | 646 | Glycylpeptide N-tetradecanoyltransferase | / | 0.441 | |
| 3ar7 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.441 | |
| 3iro | 2CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.441 | |
| 3p99 | LNP | Lanosterol 14-alpha-demethylase | / | 0.441 | |
| 3qlh | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.441 | |
| 3tam | M06 | Gag-Pol polyprotein | 2.7.7.49 | 0.441 | |
| 3w5e | NVW | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.441 | |
| 3x04 | GNP | Phosphatidylinositol 5-phosphate 4-kinase type-2 beta | 2.7.1.149 | 0.441 | |
| 4at4 | T6E | BDNF/NT-3 growth factors receptor | 2.7.10.1 | 0.441 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.441 | |
| 4dqu | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 4ea1 | 3RX | Dehydrosqualene synthase | / | 0.441 | |
| 4eiy | ZMA | Adenosine receptor A2a | / | 0.441 | |
| 4gi2 | NAP | Crotonyl-CoA carboxylase/reductase | / | 0.441 | |
| 4pv5 | CBW | Lactoylglutathione lyase | 4.4.1.5 | 0.441 | |
| 4rup | H97 | Vitamin D3 receptor A | / | 0.441 | |
| 1brp | RTL | Retinol-binding protein 4 | / | 0.440 | |
| 1bvr | THT | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 1c7o | PPG | Hemolysin | / | 0.440 | |
| 1d2s | DHT | Sex hormone-binding globulin | / | 0.440 | |
| 1g0n | NDP | Tetrahydroxynaphthalene reductase | 1.1.1.252 | 0.440 | |
| 1juj | LYA | Thymidylate synthase | 2.1.1.45 | 0.440 | |
| 1lnm | DTX | Bilin-binding protein | / | 0.440 | |
| 1lri | CLR | Beta-elicitin cryptogein | / | 0.440 | |
| 1pq6 | 965 | Oxysterols receptor LXR-beta | / | 0.440 | |
| 1wxy | FRK | Adenosine deaminase | 3.5.4.4 | 0.440 | |
| 2e98 | B29 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.440 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.440 | |
| 2g27 | 4LG | Renin | 3.4.23.15 | 0.440 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.440 | |
| 2imf | TOM | 2-hydroxychromene-2-carboxylate isomerase | 5.99.1.4 | 0.440 | |
| 2jc6 | QPP | Calcium/calmodulin-dependent protein kinase type 1D | 2.7.11.17 | 0.440 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.440 | |
| 2wd8 | VGF | Pteridine reductase | / | 0.440 | |
| 2wkm | PFY | Hepatocyte growth factor receptor | 2.7.10.1 | 0.440 | |
| 3ar4 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.440 | |
| 3b9o | FMN | Alkane monoxygenase | / | 0.440 | |
| 3clb | TMQ | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.440 | |
| 3ghw | GHW | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 3k9u | ACO | Spermidine N(1)-acetyltransferase | / | 0.440 | |
| 4at3 | LTI | BDNF/NT-3 growth factors receptor | 2.7.10.1 | 0.440 | |
| 4dc1 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.440 | |
| 4j0k | EGR | Tannase | / | 0.440 | |
| 4j6b | PLO | Cytochrome P450 monooxygenase | / | 0.440 | |
| 4zvl | FAD | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.440 |