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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2wtjWTJSerine/threonine-protein kinase Chk22.7.11.1

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
2wtjWTJSerine/threonine-protein kinase Chk22.7.11.11.000
4bdaVFBSerine/threonine-protein kinase Chk22.7.11.10.608
2wtiWTISerine/threonine-protein kinase Chk22.7.11.10.604
4a9uA9USerine/threonine-protein kinase Chk22.7.11.10.593
2xk9XK9Serine/threonine-protein kinase Chk22.7.11.10.568
3gubGUBDeath-associated protein kinase 12.7.11.10.568
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.560
2yirYIRSerine/threonine-protein kinase Chk22.7.11.10.560
2y7jB49Phosphorylase b kinase gamma catalytic chain, liver/testis isoform2.7.11.190.559
4a9tA9TSerine/threonine-protein kinase Chk22.7.11.10.558
2w7xD1ASerine/threonine-protein kinase Chk22.7.11.10.552
2xm9LWHSerine/threonine-protein kinase Chk22.7.11.10.550
4a9sRU9Serine/threonine-protein kinase Chk22.7.11.10.544
2wtdZZKSerine/threonine-protein kinase Chk22.7.11.10.538
4bdgP3JSerine/threonine-protein kinase Chk22.7.11.10.531
4a9rRU5Serine/threonine-protein kinase Chk22.7.11.10.527
1z5mLI83-phosphoinositide-dependent protein kinase 12.7.11.10.521
2pe15173-phosphoinositide-dependent protein kinase 12.7.11.10.520
2zjwREFCasein kinase II subunit alpha2.7.11.10.520
3nunJMZ3-phosphoinositide-dependent protein kinase 12.7.11.10.520
2xbjXBJSerine/threonine-protein kinase Chk22.7.11.10.518
2pe24643-phosphoinositide-dependent protein kinase 12.7.11.10.517
1h1wATP3-phosphoinositide-dependent protein kinase 12.7.11.10.516
2e9v85ASerine/threonine-protein kinase Chk12.7.11.10.515
2wtcVGMSerine/threonine-protein kinase Chk22.7.11.10.515
4ft9H4KSerine/threonine-protein kinase Chk12.7.11.10.514
4bdhWVISerine/threonine-protein kinase Chk22.7.11.10.513
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.513
1wvxBD4Death-associated protein kinase 12.7.11.10.512
2pe039Z3-phosphoinositide-dependent protein kinase 12.7.11.10.512
3bqr4RBDeath-associated protein kinase 3/0.512
4i22IREEpidermal growth factor receptor2.7.10.10.512
4d58BI9Focal adhesion kinase 12.7.10.20.511
4ftiH7KSerine/threonine-protein kinase Chk12.7.11.10.510
1rekB8LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.509
4fsqHK3Serine/threonine-protein kinase Chk12.7.11.10.509
4ft3H1KSerine/threonine-protein kinase Chk12.7.11.10.508
4enxZ20Serine/threonine-protein kinase pim-12.7.11.10.507
1yolS03Proto-oncogene tyrosine-protein kinase Src2.7.10.20.505
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.505
4ftkH9KSerine/threonine-protein kinase Chk12.7.11.10.505
2e9oA58Serine/threonine-protein kinase Chk12.7.11.10.501
3qcs3Q13-phosphoinositide-dependent protein kinase 12.7.11.10.501
4bdcODHSerine/threonine-protein kinase Chk22.7.11.10.501
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.500
4ft0HK9Serine/threonine-protein kinase Chk12.7.11.10.500
2xp2VGHALK tyrosine kinase receptor2.7.10.10.498
4bgh3I6Cyclin-dependent kinase 22.7.11.220.498
4fsuHK5Serine/threonine-protein kinase Chk12.7.11.10.498
3bhy7CPDeath-associated protein kinase 3/0.497
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.496
2hog710Serine/threonine-protein kinase Chk12.7.11.10.496
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.496
2cdz23DSerine/threonine-protein kinase PAK 42.7.11.10.495
2e9p77ASerine/threonine-protein kinase Chk12.7.11.10.495
2ydiYDISerine/threonine-protein kinase Chk12.7.11.10.495
3lctADPALK tyrosine kinase receptor2.7.10.10.495
3sc13S13-phosphoinositide-dependent protein kinase 12.7.11.10.495
3qd43Q63-phosphoinositide-dependent protein kinase 12.7.11.10.493
3s2pPMUCyclin-dependent kinase 22.7.11.220.493
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.493
4gh2HK0Serine/threonine-protein kinase Chk12.7.11.10.493
2yaaATPDeath-associated protein kinase 2/0.492
2wmqZYQSerine/threonine-protein kinase Chk12.7.11.10.491
4ftcH6KSerine/threonine-protein kinase Chk12.7.11.10.491
1pyePM1Cyclin-dependent kinase 22.7.11.220.490
2j9mPY8Cyclin-dependent kinase 22.7.11.220.490
1w0xOLOCyclin-dependent kinase 22.7.11.220.489
4fsnA58Serine/threonine-protein kinase Chk12.7.11.10.489
4ftjH8KSerine/threonine-protein kinase Chk12.7.11.10.489
4fto3HKSerine/threonine-protein kinase Chk12.7.11.10.489
4jik1KOSerine/threonine-protein kinase Chk12.7.11.10.489
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.488
4aw1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.487
4yhjAN2G protein-coupled receptor kinase 42.7.11.160.487
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.485
2vtpLZ9Cyclin-dependent kinase 22.7.11.220.485
2yitYITSerine/threonine-protein kinase Chk22.7.11.10.485
4fszHK8Serine/threonine-protein kinase Chk12.7.11.10.485
3cblSTUTyrosine-protein kinase Fes/Fps2.7.10.20.484
3rpy27ZCyclin-dependent kinase 22.7.11.220.484
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.10.484
1oiyN41Cyclin-dependent kinase 22.7.11.220.483
2cgv3B3Serine/threonine-protein kinase Chk12.7.11.10.483
2hy0306Serine/threonine-protein kinase Chk12.7.11.10.482
2ydkYDKSerine/threonine-protein kinase Chk12.7.11.10.482
3emg685Tyrosine-protein kinase SYK2.7.10.20.482
3sheI85MAP kinase-activated protein kinase 32.7.11.10.482
4rqkATP3-phosphoinositide-dependent protein kinase 12.7.11.10.482
4yuqKS1Calmodulin-like domain protein kinase/0.482
2c475IDCasein kinase I isoform gamma-2/0.481
4rqvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.481
2a0cCK9Cyclin-dependent kinase 22.7.11.220.480
3zewSTUEphrin type-B receptor 42.7.10.10.480
5aacVGHALK tyrosine kinase receptor2.7.10.10.480
5auwQUEDeath-associated protein kinase 12.7.11.10.480
2br1PFPSerine/threonine-protein kinase Chk12.7.11.10.479
2c6iDT1Cyclin-dependent kinase 22.7.11.220.479
4bdeCWSSerine/threonine-protein kinase Chk22.7.11.10.479
4ftu7HKSerine/threonine-protein kinase Chk12.7.11.10.479
2ydjYDJSerine/threonine-protein kinase Chk12.7.11.10.478
3hrfATP3-phosphoinositide-dependent protein kinase 12.7.11.10.478
3qcy3Q33-phosphoinositide-dependent protein kinase 12.7.11.10.478
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.478
2xb7GUIALK tyrosine kinase receptor2.7.10.10.477
4gfg0XFTyrosine-protein kinase SYK2.7.10.20.477
4im2BX7Serine/threonine-protein kinase TBK12.7.11.10.477
2hxq373Serine/threonine-protein kinase Chk12.7.11.10.476
3bkbSTUTyrosine-protein kinase Fes/Fps2.7.10.20.476
4ftaH5KSerine/threonine-protein kinase Chk12.7.11.10.476
1oi9N20Cyclin-dependent kinase 22.7.11.220.475
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.475
2r0uM54Serine/threonine-protein kinase Chk12.7.11.10.475
3hrcATP3-phosphoinositide-dependent protein kinase 12.7.11.10.475
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.475
4bdbODOSerine/threonine-protein kinase Chk22.7.11.10.475
2r7b2533-phosphoinositide-dependent protein kinase 12.7.11.10.474
2vu3LZECyclin-dependent kinase 22.7.11.220.474
3t8oATPRhodopsin kinase/0.474
4mq12C3Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.474
2r64740Cyclin-dependent kinase 22.7.11.220.473
5ackATP3-phosphoinositide-dependent protein kinase 12.7.11.10.473
1nvrSTUSerine/threonine-protein kinase Chk12.7.11.10.472
1oecAA2Fibroblast growth factor receptor 2/0.472
1pxmCK5Cyclin-dependent kinase 22.7.11.220.472
1urwI1PCyclin-dependent kinase 22.7.11.220.472
2biyATP3-phosphoinositide-dependent protein kinase 12.7.11.10.472
3q9xEMOCasein kinase II subunit alpha2.7.11.10.472
3tkh07SSerine/threonine-protein kinase Chk12.7.11.10.472
4anqVGHALK tyrosine kinase receptor2.7.10.10.472
4enyJ19Serine/threonine-protein kinase pim-12.7.11.10.472
4fsyHK7Serine/threonine-protein kinase Chk12.7.11.10.472
1uu3LY43-phosphoinositide-dependent protein kinase 12.7.11.10.471
2j0lANPFocal adhesion kinase 12.7.10.20.471
2qhn582Serine/threonine-protein kinase Chk12.7.11.10.471
2ycqUPXSerine/threonine-protein kinase Chk22.7.11.10.471
3cd3STUTyrosine-protein kinase Fes/Fps2.7.10.20.471
3qd33Q53-phosphoinositide-dependent protein kinase 12.7.11.10.471
3qx2X63Cyclin-dependent kinase 22.7.11.220.471
4fswHK6Serine/threonine-protein kinase Chk12.7.11.10.471
5av4GENDeath-associated protein kinase 12.7.11.10.471
1h0w207Cyclin-dependent kinase 22.7.11.220.470
1uvrBI83-phosphoinositide-dependent protein kinase 12.7.11.10.470
3orzBI43-phosphoinositide-dependent protein kinase 12.7.11.10.470
3r9dX6BCyclin-dependent kinase 22.7.11.220.470
4brxKGWFocal adhesion kinase 12.7.10.20.470
4ek610KCyclin-dependent kinase 22.7.11.220.470
4j97ACPFibroblast growth factor receptor 2/0.470
2brhDFWSerine/threonine-protein kinase Chk12.7.11.10.469
2c3lIDZSerine/threonine-protein kinase Chk12.7.11.10.469
3gc9B45Mitogen-activated protein kinase 112.7.11.240.469
4eok4SPCyclin-dependent kinase 22.7.11.220.469
4fsmHK1Serine/threonine-protein kinase Chk12.7.11.10.469
4ftm1HKSerine/threonine-protein kinase Chk12.7.11.10.469
4k8aK8AFocal adhesion kinase 12.7.10.20.469
1finATPCyclin-dependent kinase 22.7.11.220.468
1k2b0Q4Gag-Pol polyprotein3.4.23.160.468
1wvySTUDeath-associated protein kinase 12.7.11.10.468
2r3p3SCCyclin-dependent kinase 22.7.11.220.468
3ezvEZVCyclin-dependent kinase 22.7.11.220.468
3kn5ANPRibosomal protein S6 kinase alpha-52.7.11.10.468
3qcq3Q03-phosphoinositide-dependent protein kinase 12.7.11.10.468
3qxoX65Cyclin-dependent kinase 22.7.11.220.468
1aq1STUCyclin-dependent kinase 22.7.11.220.467
2c4g514Cyclin-dependent kinase 22.7.11.220.467
2objVRVSerine/threonine-protein kinase pim-12.7.11.10.467
2uzoC62Cyclin-dependent kinase 22.7.11.220.467
3lijANPCalcium/calmodulin dependent protein kinase with a kinase domain and 4 calmodulin like EF hands/0.467
4fv9E71Mitogen-activated protein kinase 12.7.11.240.467
4wboANWRhodopsin kinase/0.467
1okySTU3-phosphoinositide-dependent protein kinase 12.7.11.10.466
2r3iSCFCyclin-dependent kinase 22.7.11.220.466
3rmf20ZCyclin-dependent kinase 22.7.11.220.466
3vs7KS1Tyrosine-protein kinase HCK2.7.10.20.466
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.466
4fkpLS5Cyclin-dependent kinase 22.7.11.220.466
1gii1PUCyclin-dependent kinase 22.7.11.220.465
3nuuJOZ3-phosphoinositide-dependent protein kinase 12.7.11.10.465
3tucFPWTyrosine-protein kinase SYK2.7.10.20.465
4fv8E63Mitogen-activated protein kinase 12.7.11.240.465
1e9hINRCyclin-dependent kinase 22.7.11.220.464
1g5sI17Cyclin-dependent kinase 22.7.11.220.464
2btrU73Cyclin-dependent kinase 22.7.11.220.464
2cgx3D3Serine/threonine-protein kinase Chk12.7.11.10.464
3qqkX02Cyclin-dependent kinase 22.7.11.220.464
4bl1ANPMaternal embryonic leucine zipper kinase2.7.11.10.464
4fob0USALK tyrosine kinase receptor2.7.10.10.464
5dr6SKEAurora kinase A2.7.11.10.464
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.463
1xjdSTUProtein kinase C theta type2.7.11.130.463
2ckeIQUDeath-associated protein kinase 2/0.463
2r3kSCQCyclin-dependent kinase 22.7.11.220.463
3rm719ZCyclin-dependent kinase 22.7.11.220.463
3v8t477Tyrosine-protein kinase ITK/TSK2.7.10.20.463
4bddZ0OSerine/threonine-protein kinase Chk22.7.11.10.463
4fg9ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.463
4riyADPEpidermal growth factor receptor2.7.10.10.463
2cig1DGDihydrofolate reductase1.5.1.30.462
2qhm7CSSerine/threonine-protein kinase Chk12.7.11.10.462
2uzbC75Cyclin-dependent kinase 22.7.11.220.462
2ycsNXPSerine/threonine-protein kinase Chk22.7.11.10.462
3ggxGGXGag-Pol polyprotein/0.462
3rk507ZCyclin-dependent kinase 22.7.11.220.462
4b8lA0PAurora kinase B-A2.7.11.10.462
4fx360KCyclin-dependent kinase 22.7.11.220.462
2vv9IM9Cyclin-dependent kinase 22.7.11.220.461
3a62STURibosomal protein S6 kinase beta-12.7.11.10.461
3at4CCKCasein kinase II subunit alpha2.7.11.10.461
3rni21ZCyclin-dependent kinase 22.7.11.220.461
3tnwF18Cyclin-dependent kinase 22.7.11.220.461
4fv3EK6Mitogen-activated protein kinase 12.7.11.240.461
1ke5LS1Cyclin-dependent kinase 22.7.11.220.460
1q5kTMUGlycogen synthase kinase-3 beta2.7.11.260.460
1qpdSTUTyrosine-protein kinase Lck2.7.10.20.460
2vtiLZ3Cyclin-dependent kinase 22.7.11.220.460
2x8eX8ESerine/threonine-protein kinase Chk12.7.11.10.460
3hx4ANPCalmodulin-domain protein kinase 1/0.460
3rwpABQ3-phosphoinositide-dependent protein kinase 12.7.11.10.460
4c61LMMTyrosine-protein kinase JAK2/0.460
4fki09KCyclin-dependent kinase 22.7.11.220.460
4fkq42KCyclin-dependent kinase 22.7.11.220.460
1ke7LS3Cyclin-dependent kinase 22.7.11.220.459
2ivuZD6Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.459
3ambVX6cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.459
4ct2ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.459
4fkr45KCyclin-dependent kinase 22.7.11.220.459
4o0sADNAurora kinase A2.7.11.10.459
4yzcSTUSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.459
1gih1PUCyclin-dependent kinase 22.7.11.220.458
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.458
2ayp43ASerine/threonine-protein kinase Chk12.7.11.10.458
2xj1XJ1Serine/threonine-protein kinase pim-12.7.11.10.458
3lfnA27Cyclin-dependent kinase 22.7.11.220.458
3qxpX64Cyclin-dependent kinase 22.7.11.220.458
4b1vATPActin, alpha skeletal muscle/0.458
4fko20KCyclin-dependent kinase 22.7.11.220.458
4fod0UVALK tyrosine kinase receptor2.7.10.10.458
4fstHK4Serine/threonine-protein kinase Chk12.7.11.10.458
1tqpATPRIO-type serine/threonine-protein kinase Rio22.7.11.10.457
1v1k3FPCyclin-dependent kinase 22.7.11.220.457
2wmuZYUSerine/threonine-protein kinase Chk12.7.11.10.457
3qcx3Q23-phosphoinositide-dependent protein kinase 12.7.11.10.457
3sw418KCyclin-dependent kinase 22.7.11.220.457
3uvqFS8Mitogen-activated protein kinase 14/0.457
4bdiHAUSerine/threonine-protein kinase Chk22.7.11.10.457
4ct1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.457
4eutBX7Serine/threonine-protein kinase TBK12.7.11.10.457
4mf129YTyrosine-protein kinase ITK/TSK2.7.10.20.457
1eh4IC1Casein kinase I homolog 12.7.11.10.456
1uu7BI23-phosphoinositide-dependent protein kinase 12.7.11.10.456
2pwlACPFibroblast growth factor receptor 2/0.456
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.456
2ycfYCFSerine/threonine-protein kinase Chk22.7.11.10.456
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.456
3u4uLNHCasein kinase II subunit alpha2.7.11.10.456
4bdfH3RSerine/threonine-protein kinase Chk22.7.11.10.456
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.456
1tqmANPRIO-type serine/threonine-protein kinase Rio22.7.11.10.455
2cn8DBQSerine/threonine-protein kinase Chk22.7.11.10.455
2csnCKICasein kinase I homolog 12.7.11.10.455
2gu8796cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.455
2ijmATPFocal adhesion kinase 12.7.10.20.455
2ylrFADPhenylacetone monooxygenase1.14.13.920.455
4a06ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.455
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.455
4n0sDHCMitogen-activated protein kinase 12.7.11.240.455
1jklANPDeath-associated protein kinase 12.7.11.10.454
2bdjHETProto-oncogene tyrosine-protein kinase Src2.7.10.20.454
3bhh5CPCalcium/calmodulin-dependent protein kinase type II subunit beta2.7.11.170.454
3qa2XNAKetohexokinase/0.454
3rvg17PTyrosine-protein kinase JAK2/0.454
4njt017Protease/0.454
5av047XDeath-associated protein kinase 12.7.11.10.454
1di8DTQCyclin-dependent kinase 22.7.11.220.453
1fff0Q4Gag-Pol polyprotein3.4.23.160.453
2bdf24AProto-oncogene tyrosine-protein kinase Src2.7.10.20.453
2brnDF1Serine/threonine-protein kinase Chk12.7.11.10.453
2btsU32Cyclin-dependent kinase 22.7.11.220.453
2yfxVGHALK tyrosine kinase receptor2.7.10.10.453
3ddpRC8Cyclin-dependent kinase 22.7.11.220.453
3nga3NGCasein kinase II subunit alpha2.7.11.10.453
3pxkPXKFocal adhesion kinase 12.7.10.20.453
3ral04ZCyclin-dependent kinase 22.7.11.220.453
4ckiADNProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.453
4g160VMCasein kinase I isoform gamma-32.7.11.10.453
4g1wG1WMitogen-activated protein kinase 82.7.11.240.453
4jqeANPCasein kinase II subunit alpha2.7.11.10.453
1dq8COA3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.340.452
1ke6LS2Cyclin-dependent kinase 22.7.11.220.452
3mfsANPPeripheral plasma membrane protein CASK2.7.11.10.452
1ny3ADPMAP kinase-activated protein kinase 22.7.11.10.451
1zys199Serine/threonine-protein kinase Chk12.7.11.10.451
2i40BLZCyclin-dependent kinase 22.7.11.220.451
2w06FRVCyclin-dependent kinase 22.7.11.220.451
2x2lX2LProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.451
2ym44YMSerine/threonine-protein kinase Chk12.7.11.10.451
3ofm4B0Casein kinase II subunit alpha'2.7.11.10.451
3q92XNBKetohexokinase/0.451
4bcmT7ZCyclin-dependent kinase 22.7.11.220.451
4hyh1AMSerine/threonine-protein kinase Chk12.7.11.10.451
4s34ANPMitogen-activated protein kinase 12.7.11.240.451
5dr9SKEAurora kinase A2.7.11.10.451
1bdlIM1Gag-Pol polyprotein3.4.23.160.450
3jy0LYGSerine/threonine-protein kinase pim-12.7.11.10.450
3mfrANPPeripheral plasma membrane protein CASK2.7.11.10.450
3qtzX42Cyclin-dependent kinase 22.7.11.220.450
4btjADPTau-tubulin kinase 12.7.11.10.450
4ewhT77Activated CDC42 kinase 1/0.450
4k1b1OCSerine/threonine-protein kinase pim-12.7.11.10.450
4z9rNADOmega-3 polyunsaturated fatty acid synthase subunit PfaD/0.450
1me7RVPInosine-5'-monophosphate dehydrogenase/0.449
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.449
2vgoAD5Aurora kinase B-A2.7.11.10.449
3a99ANPSerine/threonine-protein kinase pim-12.7.11.10.449
3amaSKEcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.449
3igoANPCalmodulin-domain protein kinase 1, putative/0.449
3oafOAGDihydrofolate reductase1.5.1.30.449
3rukAERSteroid 17-alpha-hydroxylase/17,20 lyase/0.449
4fyo0VFTyrosine-protein kinase SYK2.7.10.20.449
4jajXU1Aurora kinase A2.7.11.10.449
4jlcSU6Serine/threonine-protein kinase TBK12.7.11.10.449
1vyzN5BCyclin-dependent kinase 22.7.11.220.448
2qkrIXMCdc2-like CDK2/CDC28 like protein kinase/0.448
2xikJ60Serine/threonine-protein kinase 252.7.11.10.448
2ym7YM7Serine/threonine-protein kinase Chk12.7.11.10.448
3nuyJPZ3-phosphoinositide-dependent protein kinase 12.7.11.10.448
3oxxDR7Gag-Pol polyprotein3.4.23.160.448
3qtrX36Cyclin-dependent kinase 22.7.11.220.448
3qu0X40Cyclin-dependent kinase 22.7.11.220.448
3r1yX76Cyclin-dependent kinase 22.7.11.220.448
3r7uX96Cyclin-dependent kinase 22.7.11.220.448
3umw596Serine/threonine-protein kinase pim-12.7.11.10.448
3w551FMMitogen-activated protein kinase 12.7.11.240.448
4dit0KDGlycogen synthase kinase-3 beta2.7.11.260.448
4ft5H2KSerine/threonine-protein kinase Chk12.7.11.10.448
5dosATPAurora kinase A2.7.11.10.448
2cgu3A3Serine/threonine-protein kinase Chk12.7.11.10.447
2r3lSCWCyclin-dependent kinase 22.7.11.220.447
2vtjLZ4Cyclin-dependent kinase 22.7.11.220.447
2w0jZATSerine/threonine-protein kinase Chk22.7.11.10.447
3hp552PMitogen-activated protein kinase 14/0.447
4fkt48KCyclin-dependent kinase 22.7.11.220.447
4foc0UUALK tyrosine kinase receptor2.7.10.10.447
5auvAGIDeath-associated protein kinase 12.7.11.10.447
1dw60Q4Gag-Pol polyprotein3.4.23.160.446
1nbhSAMGlycine N-methyltransferase2.1.1.200.446
1oguST8Cyclin-dependent kinase 22.7.11.220.446
1pkdUCNCyclin-dependent kinase 22.7.11.220.446
2h96893Mitogen-activated protein kinase 82.7.11.240.446
3qtsX46Cyclin-dependent kinase 22.7.11.220.446
4aua4AUCyclin-dependent kinase 62.7.11.220.446
4gu610NFocal adhesion kinase 12.7.10.20.446
4kz01UJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
1ke9LS5Cyclin-dependent kinase 22.7.11.220.445
2of2547Tyrosine-protein kinase Lck2.7.10.20.445
2w17I19Cyclin-dependent kinase 22.7.11.220.445
2wmvZYVSerine/threonine-protein kinase Chk12.7.11.10.445
2ym5YM5Serine/threonine-protein kinase Chk12.7.11.10.445
3eb0DRKUncharacterized protein/0.445
3f5p741Insulin-like growth factor 1 receptor2.7.10.10.445
3qzgX67Cyclin-dependent kinase 22.7.11.220.445
4c62XWWTyrosine-protein kinase JAK2/0.445
4dgnLU2Casein kinase II subunit alpha2.7.11.10.445
4fv1EK4Mitogen-activated protein kinase 12.7.11.240.445
4hgl0YOCasein kinase I isoform gamma-32.7.11.10.445
4nj32KDCyclin-dependent kinase 22.7.11.220.445
1ivp1ZKGag-Pol polyprotein/0.444
1pxoCK7Cyclin-dependent kinase 22.7.11.220.444
1uyrD1LAcetyl-CoA carboxylase/0.444
2aidTHKGag-Pol polyprotein3.4.23.160.444
2c6o4SPCyclin-dependent kinase 22.7.11.220.444
2fvdLIACyclin-dependent kinase 22.7.11.220.444
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.444
2j0m4STFocal adhesion kinase 12.7.10.20.444
2xngA0HAurora kinase A2.7.11.10.444
2yac937Serine/threonine-protein kinase PLK12.7.11.210.444
3bheBZNGag-Pol polyprotein3.4.23.160.444
3hdmMMGSerine/threonine-protein kinase Sgk12.7.11.10.444
3r7vZ02Cyclin-dependent kinase 22.7.11.220.444
3roy22ZCyclin-dependent kinase 22.7.11.220.444
4ansVGHALK tyrosine kinase receptor2.7.10.10.444
4kuhCAA3-hydroxybutyryl-CoA dehydrogenase/0.444
5dpvSKEAurora kinase A2.7.11.10.444
1ke8LS4Cyclin-dependent kinase 22.7.11.220.443
1q41IXMGlycogen synthase kinase-3 beta2.7.11.260.443
2a4fAAUV-1 protease/0.443
3ma301ISerine/threonine-protein kinase pim-12.7.11.10.443
4b6l9ZPSerine/threonine-protein kinase PLK32.7.11.210.443
4bc6XZNSerine/threonine-protein kinase 102.7.11.10.443
4dgo0JWCasein kinase II subunit alpha2.7.11.10.443
1phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.442
1pxpCK8Cyclin-dependent kinase 22.7.11.220.442
2jkkBI9Focal adhesion kinase 12.7.10.20.442
2pvlP55Casein kinase II subunit alpha2.7.11.10.442
3ezrEZRCyclin-dependent kinase 22.7.11.220.442
3nux3NVCyclin-dependent kinase 62.7.11.220.442
3qwkX62Cyclin-dependent kinase 22.7.11.220.442
3unk0BYCyclin-dependent kinase 22.7.11.220.442
4fz70VHTyrosine-protein kinase SYK2.7.10.20.442
4loqSB4Mitogen-activated protein kinase 14/0.442
4qgiROCGag-Pol polyprotein3.4.23.160.442
2ijmADPFocal adhesion kinase 12.7.10.20.441
2r3fSC8Cyclin-dependent kinase 22.7.11.220.441
3iggEFQCyclin-dependent kinase 22.7.11.220.441
3iok1P6Tyrosine-protein kinase JAK2/0.441
3lfsA07Cyclin-dependent kinase 22.7.11.220.441
3lpfZ77Beta-glucuronidase3.2.1.310.441
3nup3NUCyclin-dependent kinase 62.7.11.220.441
3slkNDPPolyketide synthase extender module 2/0.441
3sqq99ZCyclin-dependent kinase 22.7.11.220.441
3sw719KCyclin-dependent kinase 22.7.11.220.441
4fks46KCyclin-dependent kinase 22.7.11.220.441
4gub0Y4Casein kinase II subunit alpha2.7.11.10.441
4hvh19RTyrosine-protein kinase JAK32.7.10.20.441
4kba1QMCasein kinase I isoform delta2.7.11.10.441
4l7sG7KTyrosine-protein kinase ITK/TSK2.7.10.20.441
4lyn1YGCyclin-dependent kinase 22.7.11.220.441
4xhgADPUncharacterized protein/0.441
1bl6SB6Mitogen-activated protein kinase 14/0.440
1dz6CAMCamphor 5-monooxygenase1.14.15.10.440
1gij2PUCyclin-dependent kinase 22.7.11.220.440
2izuP01Casein kinase I isoform gamma-32.7.11.10.440
2j62GSZO-GlcNAcase NagJ/0.440
2wmtZYTSerine/threonine-protein kinase Chk12.7.11.10.440
2ym3YM3Serine/threonine-protein kinase Chk12.7.11.10.440
3cxw7CPSerine/threonine-protein kinase pim-12.7.11.10.440
3lcdBDYMacrophage colony-stimulating factor 1 receptor2.7.10.10.440
3nwq2NCGag-Pol polyprotein3.4.23.160.440
3qaiXNNKetohexokinase/0.440
3s1h56ZCyclin-dependent kinase 22.7.11.220.440
4ccqNAPThioredoxin reductase/0.440
4jvf17XRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.440