sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4lsj | LSJ | Glucocorticoid receptor |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4lsj | LSJ | Glucocorticoid receptor | / | 1.000 | |
| 2oax | SNL | Mineralocorticoid receptor | / | 0.579 | |
| 3zrb | OR8 | Progesterone receptor | / | 0.566 | |
| 3zra | ORB | Progesterone receptor | / | 0.565 | |
| 3zr7 | OR8 | Progesterone receptor | / | 0.564 | |
| 1e3k | R18 | Progesterone receptor | / | 0.561 | |
| 3d90 | NOG | Progesterone receptor | / | 0.560 | |
| 2w8y | 486 | Progesterone receptor | / | 0.552 | |
| 4a2j | AS0 | Progesterone receptor | / | 0.552 | |
| 2w8y | NDR | Progesterone receptor | / | 0.551 | |
| 4apu | A2K | Progesterone receptor | / | 0.547 | |
| 3zrb | ORC | Progesterone receptor | / | 0.546 | |
| 4p6w | MOF | Glucocorticoid receptor | / | 0.540 | |
| 2ab2 | SNL | Mineralocorticoid receptor | / | 0.538 | |
| 3vhu | SNL | Mineralocorticoid receptor | / | 0.538 | |
| 4apu | OR8 | Progesterone receptor | / | 0.534 | |
| 1sqn | NDR | Progesterone receptor | / | 0.533 | |
| 2aax | PDN | Mineralocorticoid receptor | / | 0.533 | |
| 2abi | 1CA | Mineralocorticoid receptor | / | 0.532 | |
| 3bqd | DAY | Glucocorticoid receptor | / | 0.530 | |
| 2a3i | C0R | Mineralocorticoid receptor | / | 0.529 | |
| 1y9r | 1CA | Mineralocorticoid receptor | / | 0.524 | |
| 2aa2 | AS4 | Mineralocorticoid receptor | / | 0.523 | |
| 1ya3 | STR | Mineralocorticoid receptor | / | 0.521 | |
| 2aa6 | STR | Mineralocorticoid receptor | / | 0.520 | |
| 1gs4 | ZK5 | Androgen receptor | / | 0.519 | |
| 2acl | REA | Retinoic acid receptor RXR-alpha | / | 0.518 | |
| 2amb | 17H | Androgen receptor | / | 0.517 | |
| 1p93 | DEX | Glucocorticoid receptor | / | 0.516 | |
| 2ylo | TES | Androgen receptor | / | 0.516 | |
| 1sr7 | MOF | Progesterone receptor | / | 0.513 | |
| 1zuc | T98 | Progesterone receptor | / | 0.512 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.511 | |
| 1s9q | OHT | Estrogen-related receptor gamma | / | 0.510 | |
| 1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.510 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.508 | |
| 2aa5 | STR | Mineralocorticoid receptor | / | 0.506 | |
| 2pkl | DHT | Androgen receptor | / | 0.506 | |
| 3fal | REA | Retinoic acid receptor RXR-alpha | / | 0.504 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.504 | |
| 3nr4 | PYV | Abscisic acid receptor PYL2 | / | 0.504 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.504 | |
| 4uda | DEX | Mineralocorticoid receptor | / | 0.504 | |
| 3clb | TMQ | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.501 | |
| 2ovm | AS0 | Progesterone receptor | / | 0.500 | |
| 1m9k | 7NI | Nitric oxide synthase, endothelial | 1.14.13.39 | 0.499 | |
| 2aa7 | 1CA | Mineralocorticoid receptor | / | 0.499 | |
| 2pix | DHT | Androgen receptor | / | 0.499 | |
| 3ns2 | PYV | Abscisic acid receptor PYL2 | / | 0.499 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.498 | |
| 2ovh | AS0 | Progesterone receptor | / | 0.497 | |
| 2piv | DHT | Androgen receptor | / | 0.497 | |
| 3fc6 | REA | Retinoic acid receptor RXR-alpha | / | 0.496 | |
| 1xj7 | DHT | Androgen receptor | / | 0.495 | |
| 1xq3 | R18 | Androgen receptor | / | 0.493 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.493 | |
| 2ama | DHT | Androgen receptor | / | 0.491 | |
| 2pit | DHT | Androgen receptor | / | 0.491 | |
| 3sgv | 2BJ | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.489 | |
| 4g1y | 0VO | Vitamin D3 receptor A | / | 0.489 | |
| 4oea | DHT | Androgen receptor | / | 0.489 | |
| 1t7r | DHT | Androgen receptor | / | 0.488 | |
| 1xow | R18 | Androgen receptor | / | 0.487 | |
| 2pio | DHT | Androgen receptor | / | 0.487 | |
| 4ia1 | BIV | Vitamin D3 receptor A | / | 0.487 | |
| 5k2c | ZMA | Adenosine receptor A2a | / | 0.486 | |
| 1rkh | VD2 | Vitamin D3 receptor | / | 0.485 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.485 | |
| 2qpy | DHT | Androgen receptor | / | 0.485 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.485 | |
| 1nhz | 486 | Glucocorticoid receptor | / | 0.484 | |
| 2piw | DHT | Androgen receptor | / | 0.484 | |
| 4udc | DEX | Glucocorticoid receptor | / | 0.484 | |
| 3nj0 | PYV | Abscisic acid receptor PYL2 | / | 0.483 | |
| 3zqt | TES | Androgen receptor | / | 0.483 | |
| 2has | C3O | Vitamin D3 receptor | / | 0.482 | |
| 2pir | DHT | Androgen receptor | / | 0.482 | |
| 2piu | DHT | Androgen receptor | / | 0.482 | |
| 4oha | HFT | Androgen receptor | / | 0.482 | |
| 5k2a | ZMA | Adenosine receptor A2a | / | 0.482 | |
| 2pip | DHT | Androgen receptor | / | 0.481 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.481 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.480 | |
| 2ao6 | R18 | Androgen receptor | / | 0.480 | |
| 2hb7 | O1C | Vitamin D3 receptor | / | 0.480 | |
| 2z4j | DHT | Androgen receptor | / | 0.480 | |
| 1txi | TX5 | Vitamin D3 receptor | / | 0.479 | |
| 1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.479 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.479 | |
| 2o4r | VD5 | Vitamin D3 receptor | / | 0.479 | |
| 1qnf | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.478 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.477 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.477 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.476 | |
| 1xu7 | CPS | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.476 | |
| 2g44 | T3O | Estrogen receptor | / | 0.476 | |
| 3vg9 | ZMA | Adenosine receptor A2a | / | 0.476 | |
| 1upw | 444 | Oxysterols receptor LXR-beta | / | 0.475 | |
| 1xu9 | CPS | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.475 | |
| 2j7y | E3O | Estrogen receptor beta | / | 0.475 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.475 | |
| 3mne | DEX | Glucocorticoid receptor | / | 0.475 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.474 | |
| 1r0e | DFN | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.474 | |
| 2on6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.474 | |
| 2zla | VDB | Vitamin D3 receptor | / | 0.474 | |
| 2z97 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.473 | |
| 3w0h | W12 | Vitamin D3 receptor | / | 0.473 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.473 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.472 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.472 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.472 | |
| 2zlc | VDX | Vitamin D3 receptor | / | 0.472 | |
| 4g2g | TDH | Mycocyclosin synthase | 1.14.21.9 | 0.472 | |
| 4p6x | HCY | Glucocorticoid receptor | / | 0.472 | |
| 3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.472 | |
| 1fds | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.471 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.471 | |
| 2p15 | EZT | Estrogen receptor | / | 0.471 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.471 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.471 | |
| 1qkn | RAL | Estrogen receptor beta | / | 0.470 | |
| 1vrw | NAI | Enoyl-ACP reductase | / | 0.470 | |
| 3a60 | STU | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.470 | |
| 3fzn | D7K | Benzoylformate decarboxylase | 4.1.1.7 | 0.470 | |
| 4ug9 | 1EW | Nitric oxide synthase oxygenase | 1.14.13.165 | 0.470 | |
| 5d1b | TSN | Histone deacetylase 8 | 3.5.1.98 | 0.470 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.469 | |
| 1t73 | DHT | Androgen receptor | / | 0.469 | |
| 2fai | 459 | Estrogen receptor | / | 0.469 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.469 | |
| 2ylq | TES | Androgen receptor | / | 0.469 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.469 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.469 | |
| 3oqf | S51 | Renin | 3.4.23.15 | 0.469 | |
| 4ap1 | NAP | Steroid monooxygenase | / | 0.469 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.468 | |
| 1kqw | RTL | Cellular retinol-binding protein type II | / | 0.468 | |
| 1m2z | DEX | Glucocorticoid receptor | / | 0.468 | |
| 1t65 | DHT | Androgen receptor | / | 0.468 | |
| 3byz | H11 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.468 | |
| 3w5p | 4OA | Vitamin D3 receptor | / | 0.468 | |
| 4eso | NAP | Putative oxidoreductase | / | 0.468 | |
| 1e3g | R18 | Androgen receptor | / | 0.467 | |
| 1p91 | SAM | 23S rRNA (guanine(745)-N(1))-methyltransferase | / | 0.467 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.467 | |
| 2q7l | TES | Androgen receptor | / | 0.467 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.467 | |
| 3a78 | 3EV | Vitamin D3 receptor | / | 0.467 | |
| 3fco | IIG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.467 | |
| 3lfe | Z84 | Mitogen-activated protein kinase 14 | / | 0.467 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.467 | |
| 4lsl | 1YQ | Gag-Pol polyprotein | 2.7.7.49 | 0.467 | |
| 1crb | RTL | Retinol-binding protein 1 | / | 0.466 | |
| 1e7q | NAP | GDP-L-fucose synthase | / | 0.466 | |
| 1fml | RTL | Retinol dehydratase | / | 0.466 | |
| 2fpc | SCG | Strictosidine synthase | 4.3.3.2 | 0.466 | |
| 2fs4 | PZ1 | Renin | 3.4.23.15 | 0.466 | |
| 2q66 | ATP | Poly(A) polymerase | 2.7.7.19 | 0.466 | |
| 2qd3 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.466 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.466 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.466 | |
| 3vru | YS3 | Vitamin D3 receptor | / | 0.466 | |
| 3vt6 | 5YI | Vitamin D3 receptor | / | 0.466 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.466 | |
| 4rup | H97 | Vitamin D3 receptor A | / | 0.466 | |
| 5akk | 1P8 | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.466 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.465 | |
| 1fm6 | 9CR | Retinoic acid receptor RXR-alpha | / | 0.465 | |
| 1l2j | ETC | Estrogen receptor beta | / | 0.465 | |
| 1m9j | CLW | Nitric oxide synthase, endothelial | 1.14.13.39 | 0.465 | |
| 1s19 | MC9 | Vitamin D3 receptor | / | 0.465 | |
| 1s9p | DES | Estrogen-related receptor gamma | / | 0.465 | |
| 3gyt | DL4 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.465 | |
| 3kpz | ZNE | Vitamin D3 receptor | / | 0.465 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.465 | |
| 1phg | MYT | Camphor 5-monooxygenase | 1.14.15.1 | 0.464 | |
| 1uhl | MEI | Retinoic acid receptor RXR-beta | / | 0.464 | |
| 2dhf | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.464 | |
| 2yhd | TES | Androgen receptor | / | 0.464 | |
| 3d75 | NBB | Pheromone-binding protein ASP1 | / | 0.464 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.464 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.464 | |
| 3mnp | DEX | Glucocorticoid receptor | / | 0.464 | |
| 3n63 | XFN | Nitric oxide synthase, brain | 1.14.13.39 | 0.464 | |
| 3oll | EST | Estrogen receptor beta | / | 0.464 | |
| 3w5r | LOA | Vitamin D3 receptor | / | 0.464 | |
| 4bzo | 676 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.464 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 4lwa | Q13 | Nitric oxide synthase oxygenase | 1.14.13.165 | 0.464 | |
| 4ofu | DHT | Androgen receptor | / | 0.464 | |
| 4r1l | ADP | Phenylacetate-coenzyme A ligase | / | 0.464 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.463 | |
| 1pkf | EPD | Epothilone C/D epoxidase | 1.14 | 0.463 | |
| 1t79 | DHT | Androgen receptor | / | 0.463 | |
| 1zky | 689 | Estrogen receptor | / | 0.463 | |
| 2bf7 | HBI | Pteridine reductase 1 | 1.5.1.33 | 0.463 | |
| 3arv | SAU | Chitinase A | / | 0.463 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.463 | |
| 3up0 | D7S | aceDAF-12 | / | 0.463 | |
| 3w5t | LHP | Vitamin D3 receptor | / | 0.463 | |
| 1err | RAL | Estrogen receptor | / | 0.462 | |
| 1zdw | FLV | Prenyltransferase | / | 0.462 | |
| 2q7i | TES | Androgen receptor | / | 0.462 | |
| 3vtc | TK3 | Vitamin D3 receptor | / | 0.462 | |
| 4dqu | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.462 | |
| 5hwq | CAA | Hydroxymethylglutaryl-CoA synthase | / | 0.462 | |
| 1jtq | LY3 | Thymidylate synthase | / | 0.461 | |
| 1kzj | CB3 | Thymidylate synthase | / | 0.461 | |
| 2cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.461 | |
| 3dol | GWI | Pol protein | / | 0.461 | |
| 3gyu | DL7 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.461 | |
| 3tdl | 11D | Serum albumin | / | 0.461 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.461 | |
| 4hai | I23 | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.461 | |
| 4j03 | FVS | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.461 | |
| 4q0a | 4OA | Vitamin D3 receptor A | / | 0.461 | |
| 4y8w | STR | Steroid 21-hydroxylase | / | 0.461 | |
| 1eji | THF | Serine hydroxymethyltransferase, cytosolic | / | 0.460 | |
| 1ia3 | TQ5 | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.460 | |
| 1kmv | LII | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 2bkt | RPF | Renin | 3.4.23.15 | 0.460 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.460 | |
| 3czr | 3CZ | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.460 | |
| 3u8h | BHP | Phospholipase A2, membrane associated | / | 0.460 | |
| 3vt3 | VDX | Vitamin D3 receptor | / | 0.460 | |
| 3wav | DWV | Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 | 3.1.4.39 | 0.460 | |
| 3wec | AUI | Cytochrome P450 | / | 0.460 | |
| 4fw0 | 5KJ | Nitric oxide synthase, brain | 1.14.13.39 | 0.460 | |
| 4ia2 | BIV | Vitamin D3 receptor A | / | 0.460 | |
| 4k6i | 9RA | Retinoic acid receptor RXR-alpha | / | 0.460 | |
| 1fdu | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.459 | |
| 1k74 | 9CR | Retinoic acid receptor RXR-alpha | / | 0.459 | |
| 1m9t | INE | Nitric oxide synthase, inducible | 1.14.13.39 | 0.459 | |
| 1udt | VIA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.459 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.459 | |
| 3dr1 | C5D | Vitamin D3 receptor A | / | 0.459 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.459 | |
| 4dsc | A8S | Abscisic acid receptor PYL3 | / | 0.459 | |
| 4ivy | 1GT | Estrogen receptor | / | 0.459 | |
| 4ofr | DHT | Androgen receptor | / | 0.459 | |
| 1og5 | SWF | Cytochrome P450 2C9 | / | 0.458 | |
| 1rx7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 2bbq | PFG | Thymidylate synthase | / | 0.458 | |
| 2yat | EEU | Estrogen receptor | / | 0.458 | |
| 3ue4 | DB8 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.458 | |
| 4bj9 | UHB | Tankyrase-2 | 2.4.2.30 | 0.458 | |
| 4g1d | 0VK | Vitamin D3 receptor A | / | 0.458 | |
| 4m2x | TMQ | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 1aiq | CB3 | Thymidylate synthase | / | 0.457 | |
| 1iwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.457 | |
| 1nyx | DRF | Peroxisome proliferator-activated receptor gamma | / | 0.457 | |
| 1xls | REA | Retinoic acid receptor RXR-alpha | / | 0.457 | |
| 2zl9 | VDA | Vitamin D3 receptor | / | 0.457 | |
| 3own | 3OW | Renin | 3.4.23.15 | 0.457 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.457 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.457 | |
| 4uqs | INE | Nitric oxide synthase oxygenase | 1.14.13.165 | 0.457 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.457 | |
| 2hk9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.456 | |
| 3d5q | T30 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.456 | |
| 3gmd | 2M3 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.456 | |
| 3iro | 2CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.456 | |
| 4f4d | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.456 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.456 | |
| 4l5b | 1UX | Deoxycytidine kinase | 2.7.1.74 | 0.456 | |
| 4oey | DHT | Androgen receptor | / | 0.456 | |
| 4ruj | VDX | Vitamin D3 receptor A | / | 0.456 | |
| 1ddu | CB3 | Thymidylate synthase | / | 0.455 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.455 | |
| 2j0m | 4ST | Focal adhesion kinase 1 | 2.7.10.2 | 0.455 | |
| 2piq | DHT | Androgen receptor | / | 0.455 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.455 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.455 | |
| 2xls | FAD | Putative flavin-containing monooxygenase | / | 0.455 | |
| 3e7i | B2 | Nitric oxide synthase, inducible | 1.14.13.39 | 0.455 | |
| 3maa | FKP | Adenylate cyclase type 2 | / | 0.455 | |
| 3maa | FKP | Adenylate cyclase type 5 | / | 0.455 | |
| 3w1w | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.455 | |
| 4a9m | P9M | Bromodomain-containing protein 2 | / | 0.455 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.455 | |
| 4ite | TEY | Vitamin D3 receptor | / | 0.455 | |
| 1dtp | APU | Diphtheria toxin | / | 0.454 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 1r9o | FLP | Cytochrome P450 2C9 | / | 0.454 | |
| 2o4j | VD4 | Vitamin D3 receptor | / | 0.454 | |
| 2w6o | OA3 | Biotin carboxylase | 6.3.4.14 | 0.454 | |
| 3g4i | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.454 | |
| 3qm4 | PN0 | Cytochrome P450 2D6 | / | 0.454 | |
| 3ruk | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.454 | |
| 3sp9 | IL2 | Peroxisome proliferator-activated receptor delta | / | 0.454 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.454 | |
| 4e0u | 0MV | Cyclic dipeptide N-prenyltransferase | / | 0.454 | |
| 4g20 | 484 | Vitamin D3 receptor A | / | 0.454 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.454 | |
| 1ie9 | VDX | Vitamin D3 receptor | / | 0.453 | |
| 1kl2 | FON | Serine hydroxymethyltransferase | / | 0.453 | |
| 2iod | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.453 | |
| 2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.453 | |
| 3bzu | A21 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.453 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.453 | |
| 3mno | DEX | Glucocorticoid receptor | / | 0.453 | |
| 3nks | ACJ | Protoporphyrinogen oxidase | 1.3.3.4 | 0.453 | |
| 3of2 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.453 | |
| 3vtb | TKA | Vitamin D3 receptor | / | 0.453 | |
| 4i1n | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 4oed | DHT | Androgen receptor | / | 0.453 | |
| 4ogh | HFT | Androgen receptor | / | 0.453 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.452 | |
| 1rk3 | VDX | Vitamin D3 receptor | / | 0.452 | |
| 1v35 | NAI | Enoyl-ACP reductase | / | 0.452 | |
| 3c0i | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.452 | |
| 3ch6 | 311 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.452 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.452 | |
| 3gbk | 2PQ | Peroxisome proliferator-activated receptor gamma | / | 0.452 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.452 | |
| 3mqe | 416 | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.452 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.452 | |
| 3nef | PYV | Abscisic acid receptor PYL1 | / | 0.452 | |
| 3rep | ATP | Integrin-linked protein kinase | 2.7.11.1 | 0.452 | |
| 3up3 | XCA | aceDAF-12 | / | 0.452 | |
| 4bb5 | HD2 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.452 | |
| 4c9o | CAM | Cytochrome P450 | / | 0.452 | |
| 4fvz | 4KJ | Nitric oxide synthase, brain | 1.14.13.39 | 0.452 | |
| 4hlw | TES | Androgen receptor | / | 0.452 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.452 | |
| 4oac | ADP | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.452 | |
| 1cjk | FOK | Adenylate cyclase type 2 | / | 0.451 | |
| 1cjk | FOK | Adenylate cyclase type 5 | / | 0.451 | |
| 1dhi | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1jut | LYD | Thymidylate synthase | / | 0.451 | |
| 1u1c | BAU | Uridine phosphorylase | 2.4.2.3 | 0.451 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 3c0g | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.451 | |
| 3d3e | D3E | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.451 | |
| 3dds | 26B | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.451 | |
| 3ipq | 965 | Oxysterols receptor LXR-alpha | / | 0.451 | |
| 3oey | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.451 | |
| 3s7a | 684 | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 3vn2 | TLS | Peroxisome proliferator-activated receptor gamma | / | 0.451 | |
| 3wfg | WFG | Mineralocorticoid receptor | / | 0.451 | |
| 4acc | 7YG | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.451 | |
| 4c9p | CAM | Cytochrome P450 | / | 0.451 | |
| 4gqe | 6KJ | Nitric oxide synthase, brain | 1.14.13.39 | 0.451 | |
| 4oez | DHT | Androgen receptor | / | 0.451 | |
| 4oil | HFT | Androgen receptor | / | 0.451 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.451 | |
| 5d7q | 4I5 | NAD-dependent protein deacetylase sirtuin-2 | 3.5.1 | 0.451 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.450 | |
| 1eio | GCH | Gastrotropin | / | 0.450 | |
| 2q7k | TES | Androgen receptor | / | 0.450 | |
| 2y37 | A54 | Nitric oxide synthase, inducible | 1.14.13.39 | 0.450 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.450 | |
| 3nxy | D2H | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.450 | |
| 4eil | FOL | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.450 | |
| 4g21 | 0VP | Vitamin D3 receptor A | / | 0.450 | |
| 4gm4 | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.450 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.450 | |
| 4jlj | 1NM | Deoxycytidine kinase | 2.7.1.74 | 0.450 | |
| 4muw | 2F4 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.450 | |
| 4pkw | GM6 | Lethal factor | 3.4.24.83 | 0.450 | |
| 4ruo | BIV | Vitamin D3 receptor A | / | 0.450 | |
| 5hbr | COA | Acyl-CoA synthetase (NDP forming) | / | 0.450 | |
| 1klk | PMD | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1m8h | 6NI | Nitric oxide synthase, inducible | 1.14.13.39 | 0.449 | |
| 1pz1 | NAP | General stress protein 69 | / | 0.449 | |
| 1u1d | 181 | Uridine phosphorylase | 2.4.2.3 | 0.449 | |
| 1xon | PIL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.449 | |
| 2cjf | RP4 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.449 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.449 | |
| 2har | OCC | Vitamin D3 receptor | / | 0.449 | |
| 2jj2 | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.449 | |
| 3ey4 | 352 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.449 | |
| 3l9m | L9M | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.449 | |
| 3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.449 | |
| 3qly | 55V | Uncharacterized protein | / | 0.449 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.449 | |
| 4c1i | EH9 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.449 | |
| 4cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 4j24 | EST | Estrogen receptor beta | / | 0.449 | |
| 4ktl | 1CQ | Cytochrome P450 | / | 0.449 | |
| 1fby | REA | Retinoic acid receptor RXR-alpha | / | 0.448 | |
| 1iwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 1t5z | DHT | Androgen receptor | / | 0.448 | |
| 1wlv | COA | Phenylacetic acid degradation protein PaaI | / | 0.448 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.448 | |
| 2jed | LG8 | Protein kinase C theta type | 2.7.11.13 | 0.448 | |
| 2x86 | ADP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.448 | |
| 3c1t | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.448 | |
| 3cnj | FAD | Cholesterol oxidase | 1.1.3.6 | 0.448 | |
| 3dha | C6L | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.448 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.448 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
| 3irn | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.448 | |
| 3lak | KR1 | Gag-Pol polyprotein | 2.7.7.49 | 0.448 | |
| 3lkh | LT6 | Genome polyprotein | 2.7.7.48 | 0.448 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.448 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.448 | |
| 4boe | CLR | Japanin | / | 0.448 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.448 | |
| 4uga | Q05 | Nitric oxide synthase oxygenase | 1.14.13.165 | 0.448 | |
| 5cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 5kf1 | ACO | Predicted acetyltransferase | / | 0.448 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1fp2 | HMO | Isoflavone-7-O-methyltransferase 8 | 2.1.1.150 | 0.447 | |
| 1re0 | AFB | ADP-ribosylation factor 1 | / | 0.447 | |
| 1re0 | AFB | ARF guanine-nucleotide exchange factor 1 | / | 0.447 | |
| 1suo | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.447 | |
| 1t63 | DHT | Androgen receptor | / | 0.447 | |
| 1zkn | IBM | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.447 | |
| 2a0w | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.447 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.447 | |
| 2pr2 | DG1 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.447 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 3njo | PYV | Abscisic acid receptor PYR1 | / | 0.447 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.447 | |
| 3vrv | YSD | Vitamin D3 receptor | / | 0.447 | |
| 4qa2 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.447 | |
| 4rrr | A3T | Threonine--tRNA ligase | 6.1.1.3 | 0.447 | |
| 4yek | THM | Thymidine phosphorylase | / | 0.447 | |
| 1bim | 0QB | Renin | 3.4.23.15 | 0.446 | |
| 1e1q | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.446 | |
| 1g50 | EST | Estrogen receptor | / | 0.446 | |
| 1nvt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.446 | |
| 1owm | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.446 | |
| 2aqh | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.446 | |
| 2idz | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.446 | |
| 2jiz | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.446 | |
| 2jn3 | JN3 | Fatty acid-binding protein, liver | / | 0.446 | |
| 2vn0 | TDZ | Cytochrome P450 2C8 | / | 0.446 | |
| 2yg4 | FAD | Putrescine oxidase | / | 0.446 | |
| 3eon | 341 | Glutaryl-CoA dehydrogenase | / | 0.446 | |
| 3ezp | B3N | Histone deacetylase 8 | 3.5.1.98 | 0.446 | |
| 3h0a | 9RA | Retinoic acid receptor RXR-alpha | / | 0.446 | |
| 3l6j | Z90 | Alr2278 protein | / | 0.446 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.446 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.446 | |
| 4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.446 | |
| 4g47 | TZF | Mycocyclosin synthase | 1.14.21.9 | 0.446 | |
| 4nie | NBH | Nuclear receptor ROR-gamma | / | 0.446 | |
| 4qa0 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.446 | |
| 4rrh | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.446 | |
| 4xbf | FAD | Lysine-specific histone demethylase 1A | 1 | 0.446 | |
| 1b4v | FAD | Cholesterol oxidase | 1.1.3.6 | 0.445 | |
| 1bsv | NDP | GDP-L-fucose synthase | / | 0.445 | |
| 1n83 | CLR | Nuclear receptor ROR-alpha | / | 0.445 | |
| 1own | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.445 | |
| 1ppj | ANY | Cytochrome b | / | 0.445 | |
| 1rdt | 570 | Peroxisome proliferator-activated receptor gamma | / | 0.445 | |
| 1s3y | TQT | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 2bel | CBO | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.445 | |
| 2h44 | 7CA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.445 | |
| 2ilt | NN1 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.445 | |
| 2ow3 | BIM | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.445 | |
| 2p1v | 5TN | Retinoic acid receptor RXR-alpha | / | 0.445 | |
| 2wd8 | VGF | Pteridine reductase | / | 0.445 | |
| 2xvi | FAD | Putative flavin-containing monooxygenase | / | 0.445 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.445 | |
| 4bb6 | HD1 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.445 | |
| 4dpd | DHF | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.445 | |
| 4fxf | ATP | Pyruvate kinase PKM | 2.7.1.40 | 0.445 | |
| 4ise | 1FW | Glucokinase | 2.7.1.2 | 0.445 | |
| 4o7u | THF | Thymidylate synthase | / | 0.445 | |
| 1axw | MTX | Thymidylate synthase | / | 0.444 | |
| 1hk1 | T44 | Serum albumin | / | 0.444 | |
| 1mvc | BM6 | Retinoic acid receptor RXR-alpha | / | 0.444 | |
| 1rkg | VD1 | Vitamin D3 receptor | / | 0.444 | |
| 1ro9 | 8BR | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.444 | |
| 1sbr | VIB | Putative HMP/thiamine-binding protein YkoF | / | 0.444 | |
| 1uho | VDN | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.444 | |
| 1wsv | THH | Aminomethyltransferase, mitochondrial | / | 0.444 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.444 | |
| 2hb8 | MVD | Vitamin D3 receptor | / | 0.444 | |
| 2pnu | ENM | Androgen receptor | / | 0.444 | |
| 2qo4 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.444 | |
| 2yke | YKE | Heat shock protein HSP 90-alpha | / | 0.444 | |
| 3g72 | A6T | Renin | 3.4.23.15 | 0.444 | |
| 3nrr | D16 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.444 | |
| 3p99 | LNP | Lanosterol 14-alpha-demethylase | / | 0.444 | |
| 3pd4 | A3G | Threonine--tRNA ligase | 6.1.1.3 | 0.444 | |
| 3tk3 | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.444 | |
| 3um5 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.444 | |
| 3uvv | REA | Retinoic acid receptor RXR-alpha | / | 0.444 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.444 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.444 | |
| 4c3y | ANB | 3-ketosteroid dehydrogenase | / | 0.444 | |
| 4ddl | 0JQ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.444 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.444 | |
| 4k4e | K4E | Tankyrase-1 | 2.4.2.30 | 0.444 | |
| 4m87 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.444 | |
| 4nkv | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.444 | |
| 4qmx | H8H | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.444 | |
| 4ug5 | XFK | Nitric oxide synthase oxygenase | 1.14.13.165 | 0.444 | |
| 4uym | VOR | 14-alpha sterol demethylase Cyp51B | / | 0.444 | |
| 4wa9 | AXI | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.444 | |
| 1db1 | VDX | Vitamin D3 receptor | / | 0.443 | |
| 1s0z | EB1 | Vitamin D3 receptor | / | 0.443 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1t7f | DHT | Androgen receptor | / | 0.443 | |
| 1xiu | REA | Retinoic acid receptor RXR | / | 0.443 | |
| 2cig | 1DG | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.443 | |
| 2e9a | B28 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.443 | |
| 2hc4 | VDX | Vitamin D3 receptor A | / | 0.443 | |
| 2hko | FAD | Lysine-specific histone demethylase 1A | 1 | 0.443 | |
| 2hw2 | RFP | Rifampin ADP-ribosyl transferase | / | 0.443 | |
| 2q7g | CCL | Pyrrolysine--tRNA ligase | / | 0.443 | |
| 2uxi | G50 | HTH-type transcriptional regulator TtgR | / | 0.443 | |
| 2znp | K55 | Peroxisome proliferator-activated receptor delta | / | 0.443 | |
| 3dmj | GWE | Pol protein | / | 0.443 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 3g70 | A5T | Renin | 3.4.23.15 | 0.443 | |
| 3i1y | 33N | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.443 | |
| 3p84 | FMN | Pentaerythritol tetranitrate reductase | / | 0.443 | |
| 3vuf | ADP | Granule-bound starch synthase 1, chloroplastic/amyloplastic | 2.4.1.242 | 0.443 | |
| 4ky4 | 04J | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.443 | |
| 4xe6 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 4xwt | U5P | Ribonuclease J | / | 0.443 | |
| 5h8t | RTL | Retinol-binding protein 1 | / | 0.443 | |
| 5uvi | ZMA | Adenosine receptor A2a | / | 0.443 | |
| 1cs4 | FOK | Adenylate cyclase type 2 | / | 0.442 | |
| 1cs4 | FOK | Adenylate cyclase type 5 | / | 0.442 | |
| 1dhf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1fdw | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.442 | |
| 1fko | EFZ | Gag-Pol polyprotein | 2.7.7.49 | 0.442 | |
| 1p8d | CO1 | Oxysterols receptor LXR-beta | / | 0.442 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1rx6 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1tdr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1uye | PU9 | Heat shock protein HSP 90-alpha | / | 0.442 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.442 | |
| 2g1o | 2IG | Renin | 3.4.23.15 | 0.442 | |
| 2g27 | 4LG | Renin | 3.4.23.15 | 0.442 | |
| 2hvc | LGD | Androgen receptor | / | 0.442 | |
| 2i4q | UA4 | Renin | 3.4.23.15 | 0.442 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.442 | |
| 2qbl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.442 | |
| 2v4l | ABJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.442 | |
| 2wkm | PFY | Hepatocyte growth factor receptor | 2.7.10.1 | 0.442 | |
| 2ze2 | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.442 | |
| 3c15 | FOK | Adenylate cyclase type 2 | / | 0.442 | |
| 3c15 | FOK | Adenylate cyclase type 5 | / | 0.442 | |
| 3h1v | TK1 | Glucokinase | 2.7.1.2 | 0.442 | |
| 3nmh | PYV | Abscisic acid receptor PYL2 | / | 0.442 | |
| 3ntz | 3TZ | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 3uud | EST | Estrogen receptor | / | 0.442 | |
| 3w0y | DS4 | Vitamin D3 receptor | / | 0.442 | |
| 3zbn | COA | 3-ketoacyl-CoA thiolase-like protein | / | 0.442 | |
| 4dfn | 0K1 | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.442 | |
| 4hbm | 0Y7 | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.442 | |
| 4hvi | 19S | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.442 | |
| 4kla | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.442 | |
| 4v12 | POG | MaoC like domain protein | / | 0.442 | |
| 4z63 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.442 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.442 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.442 | |
| 1ao8 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1noo | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 1yhs | STU | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.441 | |
| 2pnj | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.441 | |
| 2q70 | DC8 | Estrogen receptor | / | 0.441 | |
| 3e6o | A55 | Nitric oxide synthase, inducible | 1.14.13.39 | 0.441 | |
| 3ghv | GHC | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 3l03 | 4OH | Estrogen receptor | / | 0.441 | |
| 3n62 | XFJ | Nitric oxide synthase, brain | 1.14.13.39 | 0.441 | |
| 3vet | ADP | nebramycin 5' synthase | 6.1.2.2 | 0.441 | |
| 3vrt | YS2 | Vitamin D3 receptor | / | 0.441 | |
| 3zia | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.441 | |
| 4at5 | MUJ | BDNF/NT-3 growth factors receptor | 2.7.10.1 | 0.441 | |
| 4czt | CPS | CBL-interacting serine/threonine-protein kinase 23 | 2.7.11.1 | 0.441 | |
| 4ead | 0NP | Thymidine phosphorylase | 2.4.2.4 | 0.441 | |
| 4ge7 | 0K5 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.441 | |
| 4itf | TFY | Vitamin D3 receptor | / | 0.441 | |
| 4l9k | EHF | Serum albumin | / | 0.441 | |
| 4lwb | QJ8 | Nitric oxide synthase oxygenase | 1.14.13.165 | 0.441 | |
| 4mr6 | 1K0 | Bromodomain-containing protein 2 | / | 0.441 | |
| 6cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 3eml | ZMA | Adenosine receptor A2a | / | 0.441 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.440 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.440 | |
| 1f0l | APU | Diphtheria toxin | / | 0.440 | |
| 1fxs | NAP | GDP-L-fucose synthase | / | 0.440 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1jtv | TES | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.440 | |
| 1r8q | AFB | Cytohesin-2 | / | 0.440 | |
| 1r8q | AFB | ADP-ribosylation factor 1 | / | 0.440 | |
| 1rr6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.440 | |
| 2bxo | OPB | Serum albumin | / | 0.440 | |
| 2e9c | B75 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.440 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.440 | |
| 2g26 | 3LG | Renin | 3.4.23.15 | 0.440 | |
| 2jc6 | QPP | Calcium/calmodulin-dependent protein kinase type 1D | 2.7.11.17 | 0.440 | |
| 2o65 | MYF | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.440 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.440 | |
| 3d74 | NBB | Pheromone-binding protein ASP1 | / | 0.440 | |
| 3fwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 3kjs | DQ1 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.440 | |
| 3nxo | D2B | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 3oq1 | 3OQ | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.440 | |
| 3pe6 | ZYH | Monoglyceride lipase | / | 0.440 | |
| 3pl8 | FAD | Pyranose 2-oxidase | / | 0.440 | |
| 3r7i | X9I | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 3t3q | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.440 | |
| 3u9y | 09L | Tankyrase-2 | 2.4.2.30 | 0.440 | |
| 3vyf | VYF | Renin | 3.4.23.15 | 0.440 | |
| 4a31 | 2CB | Glycylpeptide N-tetradecanoyltransferase | / | 0.440 | |
| 4b7s | QLE | Cytochrome P450 monooxygenase PikC | / | 0.440 | |
| 4ejh | 0QA | Cytochrome P450 2A13 | 1.14.14.1 | 0.440 | |
| 4ffl | ADP | Uncharacterized protein | / | 0.440 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.440 | |
| 4i2q | 1BT | Gag-Pol polyprotein | 2.7.7.49 | 0.440 | |
| 4iv4 | 1GS | Estrogen receptor | / | 0.440 | |
| 4mlh | VO2 | Glucokinase | 2.7.1.2 | 0.440 | |
| 4u0m | GTP | Cyclic GMP-AMP synthase | / | 0.440 |