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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4dlsGNPGTPase HRas

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
4dlsGNPGTPase HRas/1.000
3rs7GNPGTPase HRas/0.864
2rgbGNPGTPase HRas/0.779
4dlzGNPGTPase HRas/0.764
4dlxGNPGTPase HRas/0.732
3rs5GNPGTPase HRas/0.711
3rslGNPGTPase HRas/0.702
2rgcGNPGTPase HRas/0.698
4g0nGNPGTPase HRas/0.690
4dlvGNPGTPase HRas/0.682
3lbnGNPGTPase HRas/0.679
4l9wGNPGTPase HRas/0.678
5difGNPGTP-binding nuclear protein Ran/0.678
3rs0GNPGTPase HRas/0.676
3l8yGNPGTPase HRas/0.674
3oivGNPGTPase HRas/0.674
3pitGNPRas-related protein M-Ras/0.674
2rgeGNPGTPase HRas/0.672
3rs4GNPGTPase HRas/0.669
4dsnGCPGTPase KRas/0.666
2c5lGTPGTPase HRas/0.665
1t91GTPRas-related protein Rab-7a/0.664
3oiwGNPGTPase HRas/0.660
1zbdGTPRas-related protein Rab-3A/0.646
3v4fGNPGTPase HRas/0.646
3i3sGNPGTPase HRas/0.643
5b2zGNPGTPase HRas/0.643
3x1zGNPRas-related protein Rap-1b/0.639
4nyiGNPGTPase HRas/0.638
5dhaGNPGTP-binding nuclear protein Ran/0.638
3kkoGNPRas-related protein M-Ras/0.635
3lbiGNPGTPase HRas/0.634
1e96GTPRas-related C3 botulinum toxin substrate 1/0.630
4hdoGNPRas-related protein Rap-1b/0.630
1g17GNPRas-related protein SEC4/0.627
5jljGNPGTP-binding nuclear protein Ran/0.627
2bkuGTPGTP-binding nuclear protein Ran/0.625
3kucGDPRas-related protein Rap-1A/0.625
4nyjGNPGTPase HRas/0.625
3oiuGNPGTPase HRas/0.622
4lv6GDPGTPase KRas/0.622
4lhwGNPRas-related protein Rab-8A/0.621
4rkfGNPRas-related protein Rab-3/0.621
3a6pGTPGTP-binding nuclear protein Ran/0.619
3kudGDPGTPase HRas/0.619
4dltGNPGTPase HRas/0.619
4k81GTPGTPase HRas/0.619
3kkqGDPRas-related protein M-Ras/0.615
4mitGTPRho-related protein racC/0.613
3lbhGNPGTPase HRas/0.610
4tq9GDPGTPase KRas/0.609
4obeGDPGTPase KRas/0.608
1yzqGNPRas-related protein Rab-6A/0.607
3ddcGNPGTPase HRas/0.607
3e5hGNPRas-related protein Rab-28/0.604
4dlwGNPGTPase HRas/0.603
2fe4GDPRas-related protein Rab-6B/0.602
3sbdGNPRas-related C3 botulinum toxin substrate 1/0.602
3w3zGTPGTP-binding nuclear protein Ran/0.602
1zd9GDPADP-ribosylation factor-like protein 8A/0.598
3tsoGNPRas-related protein Rab-25/0.598
1xtsGTPGTP-binding protein Rheb/0.596
2gilGTPRas-related protein Rab-6A/0.593
4dsoGSPGTPase KRas/0.593
1cxzGSPTransforming protein RhoA/0.589
1ibrGNPGTP-binding nuclear protein Ran/0.589
3rabGNPRas-related protein Rab-3A/0.589
2ce2GDPGTPase HRas/0.587
3bbpGTPRas-related protein Rab-6A/0.587
4qxaGTPRas-related protein Rab-9A/0.585
3oesGNPGTPase RhebL1/0.583
3a58GNPGTP-binding protein RHO1/0.582
4o25GTPGTP-binding protein Rheb/0.582
3ea5GDPGTP-binding nuclear protein Ran/0.581
2qmeGCPRas-related C3 botulinum toxin substrate 3/0.579
4o2lGTPGTP-binding protein Rheb/0.579
4hdqGNPRas-related protein Rap-1b/0.577
4lucGDPGTPase KRas/0.577
1vg8GNPRas-related protein Rab-7a/0.575
3wyfGTPGTP-binding nuclear protein/0.575
1k5dGNPGTP-binding nuclear protein Ran/0.573
1zc4GNPRas-related protein Ral-A/0.571
4l8gGDPGTPase KRas/0.571
1kmqGNPTransforming protein RhoA/0.570
1s1cGNPTransforming protein RhoA/0.570
1zc3GNPRas-related protein Ral-A/0.568
4kvgGTPRas-related protein Rap-1A/0.568
1mh1GNPRas-related C3 botulinum toxin substrate 1/0.567
1xtrGNPGTP-binding protein Rheb/0.564
4lpkGDPGTPase KRas/0.564
4uj3GNPRas-related protein Rab-11A/0.562
1m7bGTPRho-related GTP-binding protein RhoE/0.561
3k8yGNPGTPase HRas/0.561
1x1rGDPRas-related protein M-Ras/0.560
4q02GDPGTPase KRas/0.559
2gcpGSPRho-related GTP-binding protein RhoC/0.558
2x19GTPGTP-binding nuclear protein GSP1/CNR1/0.558
4ql3GDPGTPase KRas/0.558
3lawGNPRas-related protein Rab-7a/0.557
3x1wGDPRas-related protein Rap-1b/0.556
4ldjGDPGTPase KRas/0.556
4wa7GDPGTPase KRas/0.556
2ffqGSPRas-related protein Rab-6B/0.555
2zetGTPRas-related protein Rab-27B/0.554
4epwGDPGTPase KRas/0.552
3wygGTPGTP-binding nuclear protein GSP1/CNR1/0.551
4epxGDPGTPase KRas/0.550
2msdGNPMHC class I alpha chain/0.548
3tnfGNPRas-related protein Rab-8A/0.547
4l9sGDPGTPase HRas/0.547
1n6lGTPRas-related protein Rab-5A/0.546
4ol0GTPGTP-binding nuclear protein Ran/0.546
4o2rGDPGTP-binding protein Rheb/0.545
3th5GNPRas-related C3 botulinum toxin substrate 1/0.544
3cphGDPRas-related protein SEC4/0.542
3mjhGTPRas-related protein Rab-5A/0.542
3nbzGTPGTP-binding nuclear protein Ran/0.542
1yhnGTPRas-related protein Rab-7a/0.540
2fjuGSPRas-related C3 botulinum toxin substrate 1/0.540
4js0GNPCell division control protein 42 homolog/0.539
1d5cGDPGTPase (Rab6)/0.538
4q03GDPGTPase KRas/0.538
4lrwGDPGTPase KRas/0.537
3qbtGNPRas-related protein Rab-8A/0.534
4dsuGDPGTPase KRas/0.534
2rggGNPGTPase HRas/0.532
1yu9GNPRas-related protein Rab-4A/0.530
3tgpGNPGTPase HRas/0.528
3bc1GNPRas-related protein Rab-27A/0.527
4gzlGNPRas-related C3 botulinum toxin substrate 1/0.527
1z2aGDPRas-related protein Rab-23/0.524
4uj5GNPRas-related protein Rab-11A/0.524
1z0dGDPRas-related protein Rab-5C/0.523
2mscGDPMHC class I alpha chain/0.521
2w2xGSPRas-related C3 botulinum toxin substrate 2/0.520
1a2bGSPTransforming protein RhoA/0.519
1oixGDPRas-related protein Rab-11A/0.519
1tu3GNPRas-related protein Rab-5A/0.518
3sbeGNPRas-related C3 botulinum toxin substrate 1/0.518
4cymGCPRas-related protein Rab-32/0.518
1ow3GDPTransforming protein RhoA/0.512
1z2cGNPRho-related GTP-binding protein RhoC/0.510
4xvqGNPGTPase HRas/0.510
2ov2GCPRas-related C3 botulinum toxin substrate 3/0.508
4xvrGNPGTPase HRas/0.508
2a9y26AAdenosine kinase2.7.1.200.507
2fg5GNPRas-related protein Rab-31/0.505
3k9lGNPGTPase HRas/0.505
1lfdGNPGTPase HRas/0.504
4cidANPEH domain-containing protein 2/0.504
1g16GDPRas-related protein SEC4/0.503
5hpyGDPTransforming protein RhoA/0.502
3eg5GNPCell division control protein 42 homolog/0.498
2mseGNPMHC class I alpha chain/0.497
4g2i0VQVitamin D3 receptor/0.492
5c46GSPRas-related protein Rab-11A/0.491
2cl6CAGGTPase HRas/0.490
1z0aGDPRas-related protein Rab-2A/0.489
2rdn1PL1-deoxypentalenic acid 11-beta-hydroxylase1.14.11.350.489
4dxaGSPRas-related protein Rap-1b/0.489
3k7mFAD6-hydroxy-L-nicotine oxidase/0.487
4xoiGTPTransforming protein RhoA/0.487
4paoGSPGuanine nucleotide-binding protein G(i) subunit alpha-1/0.486
1rzuADPGlycogen synthase 12.4.1.210.483
2bmeGNPRas-related protein Rab-4A/0.483
4h6uACOAlpha-tubulin N-acetyltransferase 1/0.483
2clsGTPRho-related GTP-binding protein Rho6/0.482
2xtzGSPGuanine nucleotide-binding protein alpha-1 subunit/0.482
1gwnGTPRho-related GTP-binding protein RhoE/0.481
3e32ED2Protein farnesyltransferase subunit beta2.5.1.580.481
2v59LZKBiotin carboxylase6.3.4.140.479
4h6zACOAlpha-tubulin N-acetyltransferase 1/0.479
4imgNGFN-acetylneuraminate lyase/0.479
2q7oIMHPurine nucleoside phosphorylase2.4.2.10.478
1x2hLPALipoate-protein ligase A6.3.1.200.477
5iu86DZAdenosine receptor A2a/0.476
2d4h5GPGuanylate-binding protein 1/0.475
2p2lGDPRas-related C3 botulinum toxin substrate 1/0.475
1ay0TPPTransketolase 12.2.1.10.474
1cjtFOKAdenylate cyclase type 2/0.474
1cjtFOKAdenylate cyclase type 5/0.474
1tkaN3TTransketolase 12.2.1.10.474
2bxqIMNSerum albumin/0.474
2oegUPGUDP-glucose pyrophosphorylase/0.474
3t1tGDPProbable gliding protein mglA/0.474
4iteTEYVitamin D3 receptor/0.474
2a9z26AAdenosine kinase2.7.1.200.472
3djfBC3Purine nucleoside phosphorylase/0.472
2g0nGDPRas-related C3 botulinum toxin substrate 3/0.471
3i5xANPATP-dependent RNA helicase MSS116, mitochondrial3.6.4.130.471
1culFOKAdenylate cyclase type 2/0.470
1culFOKAdenylate cyclase type 5/0.470
1qyxASDEstradiol 17-beta-dehydrogenase 11.1.1.620.470
2p1u4TNRetinoic acid receptor RXR-alpha/0.470
3c14GSPGuanine nucleotide-binding protein G(s) subunit alpha isoforms short/0.470
3vmmP0DAlanine--anticapsin ligase/0.470
4ihjGTPTubulin alpha-1B chain/0.470
4kp61S1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.470
4fgcPQ0NADPH-dependent 7-cyano-7-deazaguanine reductase1.7.1.130.469
1mrqSTRAldo-keto reductase family 1 member C1/0.468
1qm5PLPMaltodextrin phosphorylase2.4.1.10.468
2x06NADL-sulfolactate dehydrogenase/0.468
2xk4OL2Serine/threonine-protein kinase Nek22.7.11.10.468
4n3l2FNProthrombin3.4.21.50.468
1d3dBZTProthrombin3.4.21.50.467
1g7vPAI2-dehydro-3-deoxyphosphooctonate aldolase2.5.1.550.467
1gtrATPGlutamine--tRNA ligase6.1.1.180.467
3exhTPPPyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial1.2.4.10.467
3exhTPPPyruvate dehydrogenase E1 component subunit beta, mitochondrial1.2.4.10.467
4u9zCOAAlpha-tubulin N-acetyltransferase 1/0.467
1giaGSPGuanine nucleotide-binding protein G(i) subunit alpha-1/0.466
2hamC33Vitamin D3 receptor/0.466
2xkfBX1Serine/threonine-protein kinase Nek22.7.11.10.466
2zi53L1Deoxycytidine kinase2.7.1.740.466
5iu4ZMAAdenosine receptor A2a/0.466
2ic5GNPRas-related C3 botulinum toxin substrate 3/0.465
3sqxANPATP-dependent RNA helicase MSS116, mitochondrial3.6.4.130.465
3tklGTPRas-related protein Rab-1A/0.465
4wbnGTPTubulin alpha-1B chain/0.465
4wda2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.465
1cjvFOKAdenylate cyclase type 2/0.464
1cjvFOKAdenylate cyclase type 5/0.464
4feu537Aminoglycoside 3'-phosphotransferase AphA1-IAB/0.464
4oe4NADDelta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial1.2.1.880.464
4tv9GTPTubulin alpha-1B chain/0.464
2ab8MTPAdenosine kinase2.7.1.200.463
2ic5GDPRas-related C3 botulinum toxin substrate 3/0.463
3b9lAZZSerum albumin/0.463
3c14FOKAdenylate cyclase type 2/0.463
3c14FOKAdenylate cyclase type 5/0.463
1rszDIHPurine nucleoside phosphorylase2.4.2.10.462
1uadGNPRas-related protein Ral-A/0.462
3zvuA8SAbscisic acid receptor PYR1/0.462
4xg1LLPDiaminopimelate decarboxylase/0.462
5jqgGTPTubulin alpha-1B chain/0.462
1cjuFOKAdenylate cyclase type 2/0.461
1cjuFOKAdenylate cyclase type 5/0.461
2iutAGSDNA translocase FtsK/0.461
3g4lROFcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.461
3k4s0MOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.461
3nxvD2FDihydrofolate reductase1.5.1.30.461
5iubCLRAdenosine receptor A2a/0.461
1bnuAL3Carbonic anhydrase 24.2.1.10.460
2zhw12UProthrombin3.4.21.50.460
3sqzCOAPutative hydroxymethylglutaryl-CoA synthase/0.460
3w0aDS5Vitamin D3 receptor/0.460
4l1xSTRAldo-keto reductase family 1 member C2/0.460
4lb2DM5Serum albumin/0.460
4llkMEWcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.460
4mzuTYDWxcM-like protein/0.460
4q0a4OAVitamin D3 receptor A/0.460
1cg6MTAS-methyl-5'-thioadenosine phosphorylase/0.459
1qoqIGPTryptophan synthase alpha chain/0.459
2c54NADGDP-mannose 3,5-epimerase5.1.3.180.459
3eon341Glutaryl-CoA dehydrogenase/0.459
4wctFADFructosyl amine:oxygen oxidoreductase/0.459
1culGSPGuanine nucleotide-binding protein G(s) subunit alpha isoforms short/0.458
3lfm3DTAlpha-ketoglutarate-dependent dioxygenase FTO/0.458
4imfSI3N-acetylneuraminate lyase/0.458
1v8kANPKinesin-like protein KIF2C/0.457
2hvdADPNucleoside diphosphate kinase A2.7.4.60.457
2j0vGDPRac-like GTP-binding protein ARAC7/0.457
2z4sADPChromosomal replication initiator protein DnaA/0.457
3hmvHBTcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.457
3iogSDFMetallo-beta-lactamase type 2/0.457
3vhxGTPADP-ribosylation factor 6/0.457
4pahLNRPhenylalanine-4-hydroxylase1.14.16.10.457
4qx5CMPcGMP-dependent protein kinase 12.7.11.120.457
1oc1ASVIsopenicillin N synthase1.21.3.10.456
2aclL05Oxysterols receptor LXR-alpha/0.456
2gvdFKPAdenylate cyclase type 2/0.456
2gvdFKPAdenylate cyclase type 5/0.456
2q3fGNPRas-related GTP-binding protein D/0.456
2xk6EQHSerine/threonine-protein kinase Nek22.7.11.10.456
2zruFMNIsopentenyl-diphosphate delta-isomerase/0.456
3em0CHDFatty acid-binding protein 6, ileal (gastrotropin)/0.456
3p1799PProthrombin3.4.21.50.456
4bqwQNMEgl nine homolog 1/0.456
4bs4A64Tankyrase-22.4.2.300.456
4ixd1HVIntegrin alpha-L/0.456
4jq2SUZAldo-keto reductase family 1 member C2/0.456
4xo7ASDAldo-keto reductase family 1 member C2/0.456
1jtvTESEstradiol 17-beta-dehydrogenase 11.1.1.620.455
1ttm667Carbonic anhydrase 24.2.1.10.455
1ve3SAMUncharacterized protein/0.455
3dcsMZMCarbonic anhydrase 24.2.1.10.455
4bahMELProthrombin3.4.21.50.455
4phlPILPhosphodiesterase/0.455
1mlzPLPAdenosylmethionine-8-amino-7-oxononanoate aminotransferase2.6.1.620.454
1rt9IMHPurine nucleoside phosphorylase2.4.2.10.454
1y3aGDPGuanine nucleotide-binding protein G(i) subunit alpha-1/0.454
2hekGDPUncharacterized protein/0.454
2v8pCDP4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.454
2vbpVB1Isopenicillin N synthase1.21.3.10.454
3fr5I4AFatty acid-binding protein, adipocyte/0.454
3maaFKPAdenylate cyclase type 2/0.454
3maaFKPAdenylate cyclase type 5/0.454
4bfvZVVPantothenate kinase2.7.1.330.454
4k5o1OTM1 family aminopeptidase3.4.110.454
4ytnFD8Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial/0.454
4ytnFD8Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial/0.454
4ytnFD8Succinate dehydrogenase cytochrome b560/0.454
5fd8A5APutative carboxypeptidase yocD/0.454
1d3pBT3Prothrombin3.4.21.50.453
1jnrFADAdenylylsulfate reductase, subunit A (AprA)/0.453
1x1aSAMC-20 methyltransferase/0.453
1ykdCMPAdenylate cyclase/0.453
2fhjMFNFormylmethanofuran--tetrahydromethanopterin formyltransferase2.3.1.1010.453
2idoTMPDNA polymerase III subunit epsilon2.7.7.70.453
3bi2FADPolyamine oxidase FMS1/0.453
3fhxPLPPyridoxal kinase2.7.1.350.453
3w0c6DSVitamin D3 receptor/0.453
4b1fKRHGlutamate racemase/0.453
4bakM67Prothrombin3.4.21.50.453
4i9z5BAcGMP-specific 3',5'-cyclic phosphodiesterase/0.453
5h8tRTLRetinol-binding protein 1/0.453
3c15GSPGuanine nucleotide-binding protein G(s) subunit alpha isoforms short/0.452
3dynPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.452
3pqbVGPPutative oxidoreductase/0.452
3t8vBTJM1 family aminopeptidase3.4.110.452
4c717RD3-oxoacyl-ACP synthase/0.452
4ycoFMNtRNA-dihydrouridine(16) synthase/0.452
4zzi1NSNAD-dependent protein deacetylase sirtuin-13.5.10.452
1obnASVIsopenicillin N synthase1.21.3.10.451
1ozqPRFQueuine tRNA-ribosyltransferase2.4.2.290.451
1ygkRRCPyridoxal kinase2.7.1.350.451
2b1z17MEstrogen receptor/0.451
2bdyUNBProthrombin3.4.21.50.451
2ociTYCValacyclovir hydrolase3.10.451
2v3hI25Prothrombin3.4.21.50.451
3ml8ML8Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.451
3q7fED2Uncharacterized protein/0.451
3qeoLLTDeoxycytidine kinase2.7.1.740.451
3rl35GPMetallophosphoesterase MPPED23.10.451
4a81DXCMajor pollen allergen Bet v 1-A/0.451
4buxF35Tankyrase-22.4.2.300.451
4fevPP1Aminoglycoside 3'-phosphotransferase AphA1-IAB/0.451
4frkDWDBeta-secretase 13.4.23.460.451
4j3lAJ5Tankyrase-22.4.2.300.451
4j7gTRHPCZA361.3/0.451
5hbsRTLRetinol-binding protein 1/0.451
1mznBM6Retinoic acid receptor RXR-alpha/0.450
1ro98BRcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.450
2w71L23Biotin carboxylase6.3.4.140.450
3akm11DFatty acid-binding protein, intestinal/0.450
3c16FOKAdenylate cyclase type 2/0.450
3c16FOKAdenylate cyclase type 5/0.450
3h4vNAPPteridine reductase 11.5.1.330.450
5stdUNNScytalone dehydratase4.2.1.940.450
1a9sNOSPurine nucleoside phosphorylase2.4.2.10.449
1u0hFOKAdenylate cyclase type 2/0.449
1u0hFOKAdenylate cyclase type 5/0.449
1zgi382Prothrombin3.4.21.50.449
2ji9TPWOxalyl-CoA decarboxylase4.1.1.80.449
2vczVC3Hematopoietic prostaglandin D synthase/0.449
2wo7ASVIsopenicillin N synthase1.21.3.10.449
2xvw9NRSerum albumin/0.449
2zb8IMNProstaglandin reductase 21.3.1.480.449
3gncQQQGlutaryl-CoA dehydrogenase/0.449
3umsGDPGuanine nucleotide-binding protein G(i) subunit alpha-1/0.449
4ddl0JQcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.449
4dvi2IWTankyrase-12.4.2.300.449
4tjy3GNTankyrase-22.4.2.300.449
1gilGSPGuanine nucleotide-binding protein G(i) subunit alpha-1/0.448
3t3r9PLCytochrome P450 2A61.14.130.448
3zbnCOA3-ketoacyl-CoA thiolase-like protein/0.448
4bfwZVWPantothenate kinase2.7.1.330.448
4d9fDCSD-cysteine desulfhydrase/0.448
4gusFADLysine-specific histone demethylase 1B10.448
4u7wNDPMxaA/0.448
5pahLDPPhenylalanine-4-hydroxylase1.14.16.10.448
1q63AIQQueuine tRNA-ribosyltransferase2.4.2.290.447
1qyw5SDEstradiol 17-beta-dehydrogenase 11.1.1.620.447
1upw444Oxysterols receptor LXR-beta/0.447
1xomCIOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.447
1ygjRMCPyridoxal kinase2.7.1.350.447
2e0nSAHPrecorrin-2 C20-methyltransferase/0.447
2p1t3TNRetinoic acid receptor RXR-alpha/0.447
2rtdBTNStreptavidin/0.447
2yg5FADPutrescine oxidase/0.447
3dheANDEstradiol 17-beta-dehydrogenase 11.1.1.620.447
3hwxTPP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.447
3v2uATPProtein GAL3/0.447
3vv8B02Beta-secretase 13.4.23.460.447
3zkyWT4Isopenicillin N synthase1.21.3.10.447
3zu2NAIEnoyl-[acyl-carrier-protein] reductase [NADH]/0.447
4ubuCOASteroid 3-ketoacyl-CoA thiolase/0.447
1hdrNADDihydropteridine reductase1.5.1.340.446
1pw6FRBInterleukin-2/0.446
1towCRZFatty acid-binding protein, adipocyte/0.446
1x1cSAHC-20 methyltransferase/0.446
1x7jGENEstrogen receptor beta/0.446
2fm0M98cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.446
2h15B19Carbonic anhydrase 24.2.1.10.446
2ok7FADFerredoxin--NADP reductase, apicoplast/0.446
2re8GSUGlutamine--tRNA ligase6.1.1.180.446
3a783EVVitamin D3 receptor/0.446
3cehAVEGlycogen phosphorylase, liver form2.4.1.10.446
3dr1C5DVitamin D3 receptor A/0.446
3iktNADRedox-sensing transcriptional repressor Rex/0.446
3kz1GSPTransforming protein RhoA/0.446
3sfxJANUncharacterized protein/0.446
3sqwANPATP-dependent RNA helicase MSS116, mitochondrial3.6.4.130.446
4i1nFOLDihydrofolate reductase1.5.1.30.446
4j8tDOGUncharacterized PhzA/B-like protein PA3332/0.446
4jlm1NNDeoxycytidine kinase2.7.1.740.446
4k6i9RARetinoic acid receptor RXR-alpha/0.446
4pl9ADPEthylene receptor 1/0.446
4pnmNU1Tankyrase-22.4.2.300.446
1c3x8IGPurine nucleoside phosphorylase2.4.2.10.445
1cnfFADNitrate reductase [NADH]1.7.1.10.445
1crbRTLRetinol-binding protein 1/0.445
1d6w00RProthrombin3.4.21.50.445
1gsfEAAGlutathione S-transferase A12.5.1.180.445
1lwxAZDNucleoside diphosphate kinase, cytosolic2.7.4.60.445
1mx0ANPType 2 DNA topoisomerase 6 subunit B/0.445
1q12ATPMaltose/maltodextrin import ATP-binding protein MalK/0.445
1w19T1P6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.445
2bzgSAHThiopurine S-methyltransferase2.1.1.670.445
2pbwDOQGlutamate receptor ionotropic, kainate 1/0.445
2pksG44Prothrombin3.4.21.50.445
3biz61EWee1-like protein kinase2.7.10.20.445
3keqNADRedox-sensing transcriptional repressor Rex/0.445
3ksqZ96Protein farnesyltransferase subunit beta2.5.1.580.445
3lq2TDPPyruvate dehydrogenase E1 component1.2.4.10.445
3tfuPL8Adenosylmethionine-8-amino-7-oxononanoate aminotransferase2.6.1.620.445
3ziaADPATP synthase subunit beta, mitochondrial3.6.3.140.445
4azwATPO-antigen chain terminator bifunctional methyltransferase/kinase WbdD/0.445
4jxxATPGlutamine--tRNA ligase6.1.1.180.445
4zo3C6LAcylhomoserine lactonase/0.445
5k2bZMAAdenosine receptor A2a/0.445
1z71L17Prothrombin3.4.21.50.444
2a1hGBNBranched-chain-amino-acid aminotransferase, mitochondrial2.6.1.420.444
2ea2F77Methionine aminopeptidase 2/0.444
2hveADPNucleoside diphosphate kinase A2.7.4.60.444
2i0v6C3Macrophage colony-stimulating factor 1 receptor2.7.10.10.444
2iodMYCDihydroflavonol 4-reductase1.1.1.2190.444
2r6jNDPEugenol synthase 11.1.1.3180.444
2r8oT5XTransketolase 1/0.444
2rbeZMGCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.444
2wvlGDDMannosyl-3-phosphogylcerate synthase/0.444
2ydvNECAdenosine receptor A2a/0.444
3kxoKXOHematopoietic prostaglandin D synthase/0.444
3qpoPFRcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.444
4lngJANCaaX farnesyltransferase beta subunit Ram1/0.444
4o0mATPCircadian clock protein kinase KaiC2.7.11.10.444
1rr6IMHPurine nucleoside phosphorylase2.4.2.10.443
1s19MC9Vitamin D3 receptor/0.443
1sd1FMCS-methyl-5'-thioadenosine phosphorylase/0.443
1wlvCOAPhenylacetic acid degradation protein PaaI/0.443
2gjlFMNNitronate monooxygenase1.13.12.160.443
2jb4A14Isopenicillin N synthase1.21.3.10.443
2r0pK2CPutative FAD-monooxygenase/0.443
2weyEV1cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.443
2xvv9DNSerum albumin/0.443
2y8lADP5'-AMP-activated protein kinase subunit gamma-1/0.443
3c27DKKProthrombin3.4.21.50.443
4avuLDRTankyrase-22.4.2.300.443
4bewACPSarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.443
4cvmANPUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase/0.443
4g2gTDHMycocyclosin synthase1.14.21.90.443
4klnAGSTransitional endoplasmic reticulum ATPase3.6.4.60.443
1a4rGNHCell division control protein 42 homolog/0.442
1jwtBLIProthrombin3.4.21.50.442
1k22MELProthrombin3.4.21.50.442
1kquBR4Phospholipase A2, membrane associated/0.442
1ky2GNPGTP-binding protein YPT7/0.442
1nueGDPNucleoside diphosphate kinase B2.7.4.60.442
1oxoIK2Aspartate aminotransferase, mitochondrial2.6.1.10.442
1stdBFSScytalone dehydratase4.2.1.940.442
1xmmM7Gm7GpppX diphosphatase3.6.1.590.442
2a5kAZPReplicase polyprotein 1ab3.4.220.442
2yg4FADPutrescine oxidase/0.442
3ewsADPATP-dependent RNA helicase DDX19B3.6.4.130.442
3qen5BTDeoxycytidine kinase2.7.1.740.442
3vrbFTNSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial/0.442
3vrbFTNCytochrome b-large subunit/0.442
4j21AJ6Tankyrase-22.4.2.300.442
4j531J4Serine/threonine-protein kinase PLK12.7.11.210.442
4jdaA9SAbscisic acid receptor PYL3/0.442
4mo82VQCarbonic anhydrase 24.2.1.10.442
4qzuRTLRetinol-binding protein 2/0.442
5fsi8DG7,8-dihydro-8-oxoguanine triphosphatase3.6.1.550.442
1e0jANPDNA primase/helicase2.7.70.441
1kyxCRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.441
1m8kNADNicotinamide-nucleotide adenylyltransferase2.7.7.10.441
1zrb062Prothrombin3.4.21.50.441
2a0xDIHPurine nucleoside phosphorylase2.4.2.10.441
2e7zMGDAcetylene hydratase/0.441
2o1sTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.441
2stdCRPScytalone dehydratase4.2.1.940.441
2yloTESAndrogen receptor/0.441
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.441
3k0fATPCircadian clock protein kinase KaiC2.7.11.10.441
3mjrAC2Deoxycytidine kinase2.7.1.740.441
3nh8DC2N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming)3.5.1.1140.441
4b67NAPL-ornithine N(5)-monooxygenase/0.441
4ead0NPThymidine phosphorylase2.4.2.40.441
4g0k0VSGlutathionyl-hydroquinone reductase YqjG1.80.441
4id9NADPutative UDP-glucose 4-epimerase/0.441
4l2g1V4Tankyrase-22.4.2.300.441
4tuyGTPTubulin alpha-1B chain/0.441
4yaw2AMNADPH--cytochrome P450 reductase/0.441
1qiqACCIsopenicillin N synthase1.21.3.10.440
1qzzSAMAclacinomycin 10-hydroxylase RdmB4.1.10.440
2vmyFFOSerine hydroxymethyltransferase/0.440
2zgb21UProthrombin3.4.21.50.440
3bxxQUEDihydroflavonol 4-reductase1.1.1.2190.440
3fhxPXLPyridoxal kinase2.7.1.350.440
3qv1NADGlyceraldehyde-3-phosphate dehydrogenase GAPA1, chloroplastic1.2.1.130.440
3tfjTHGDimethylsulfonioproprionate demethylase DmdA2.1.1.2690.440
3wqtANPCell division protein FtsA/0.440
4bfuZVUPantothenate kinase2.7.1.330.440
4g47TZFMycocyclosin synthase1.14.21.90.440
4m8e29VRetinoic acid receptor RXR-alpha/0.440
4nbb9CATerminal oxygenase component of carbazole/0.440