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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4c5cATPD-alanine--D-alanine ligase B6.3.2.4

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4c5cATPD-alanine--D-alanine ligase B6.3.2.41.000
4c5bADPD-alanine--D-alanine ligase B6.3.2.40.571
2pywADPMethylthioribose kinase2.7.1.1000.556
1cm8ANPMitogen-activated protein kinase 12/0.528
1tduCB3Thymidylate synthase/0.525
4fflADPUncharacterized protein/0.522
3wo0ADPAlanine--anticapsin ligase/0.516
3q5iANPProtein kinase, putative/0.515
4eomATPCyclin-dependent kinase 22.7.11.220.511
2pmlANPUncharacterized protein/0.510
5e92ANPTGF-beta receptor type-22.7.11.300.506
3my5RFZCyclin-dependent kinase 22.7.11.220.505
3r8uZ31Cyclin-dependent kinase 22.7.11.220.504
2r5tANPSerine/threonine-protein kinase Sgk12.7.11.10.503
4eos1ROCyclin-dependent kinase 22.7.11.220.502
2pz5ACPFibroblast growth factor receptor 2/0.501
5ckwANPUncharacterized protein/0.499
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.497
4qpmADPMitotic checkpoint serine/threonine-protein kinase BUB12.7.11.10.497
1phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.496
4ysjADPCalmodulin-like domain protein kinase/0.495
2yw2ATPPhosphoribosylamine--glycine ligase/0.494
5bpfADPD-alanine--D-alanine ligase/0.494
1qmzATPCyclin-dependent kinase 22.7.11.220.493
3l08ZIGPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.492
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.491
3a99ANPSerine/threonine-protein kinase pim-12.7.11.10.491
3wnzADPAlanine--anticapsin ligase/0.491
2hgsADPGlutathione synthetase6.3.2.30.490
3nszANPCasein kinase II subunit alpha2.7.11.10.488
4ful0VUPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.488
1e8zSTUPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.487
2a19ANPInterferon-induced, double-stranded RNA-activated protein kinase2.7.11.10.487
4azwATPO-antigen chain terminator bifunctional methyltransferase/kinase WbdD/0.486
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.485
3orzBI43-phosphoinositide-dependent protein kinase 12.7.11.10.485
4fhk0U0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.485
4ft0HK9Serine/threonine-protein kinase Chk12.7.11.10.485
2b9iADPMitogen-activated protein kinase FUS32.7.11.240.484
2bbqPFGThymidylate synthase/0.484
2qoqANPEphrin type-A receptor 32.7.10.10.484
4aw0ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.484
4ndnSAMS-adenosylmethionine synthase isoform type-22.5.1.60.484
4rqkATP3-phosphoinositide-dependent protein kinase 12.7.11.10.483
1gy3ATPCyclin-dependent kinase 22.7.11.220.481
1jkkANPDeath-associated protein kinase 12.7.11.10.481
2henADPEphrin type-B receptor 22.7.10.10.481
2w4jADPDeath-associated protein kinase 12.7.11.10.481
3r8vZ62Cyclin-dependent kinase 22.7.11.220.481
3zdu38RCyclin-dependent kinase-like 32.7.11.220.481
3qcs3Q13-phosphoinositide-dependent protein kinase 12.7.11.10.480
4dcaADPAminoglycoside phosphotransferase/0.480
4y12AGSSerine/threonine-protein kinase PknG2.7.11.10.480
5cvhADPCasein kinase II subunit alpha2.7.11.10.480
4kd11QKCyclin-dependent kinase 22.7.11.220.479
4e6q0NVTyrosine-protein kinase JAK2/0.478
4gh2HK0Serine/threonine-protein kinase Chk12.7.11.10.478
4gvjADPNon-receptor tyrosine-protein kinase TYK22.7.10.20.478
3ls8AJZPhosphatidylinositol 3-kinase catalytic subunit type 32.7.1.1370.477
4b8lA0PAurora kinase B-A2.7.11.10.477
4fsnA58Serine/threonine-protein kinase Chk12.7.11.10.476
4oa9ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.476
3oquA8SAbscisic acid receptor PYL9/0.475
3orpAGSSerine/threonine protein kinase/0.475
3t9fADPInositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2/0.475
4eoi1ROCyclin-dependent kinase 22.7.11.220.475
4o1pANPRibonuclease L/0.475
3nieANPMitogen-activated protein kinase/0.474
3oriAGSSerine/threonine protein kinase/0.474
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.474
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.474
4fvqATPTyrosine-protein kinase JAK2/0.474
4ii5ADPCyclin-dependent kinase 22.7.11.220.474
1e7vLY2Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.473
1ykdCMPAdenylate cyclase/0.473
2acxANPG protein-coupled receptor kinase 62.7.11.160.473
2hy0306Serine/threonine-protein kinase Chk12.7.11.10.473
2izsBRQCasein kinase I isoform gamma-32.7.11.10.473
3c4wATPRhodopsin kinase/0.473
5auwQUEDeath-associated protein kinase 12.7.11.10.473
3qcy3Q33-phosphoinositide-dependent protein kinase 12.7.11.10.472
3qtsX46Cyclin-dependent kinase 22.7.11.220.472
3w0pADPHygromycin-B 4-O-kinase2.7.1.1630.472
3zm9QMQCholine kinase alpha2.7.1.320.472
4c4iX20Dual specificity protein kinase TTK2.7.12.10.472
4rqvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.472
5c1pADPD-alanine--D-alanine ligase/0.472
5iqhGNPBifunctional AAC/APH2.3.10.472
2hfnFMNActivator of photopigment and puc expression/0.471
2pzpACPFibroblast growth factor receptor 2/0.471
3wo1ADPAlanine--anticapsin ligase/0.471
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.471
1j1cADPGlycogen synthase kinase-3 beta2.7.11.260.470
3ia4MTXDihydrofolate reductase/0.470
3orlAGSSerine/threonine protein kinase/0.470
3tnwF18Cyclin-dependent kinase 22.7.11.220.470
4bcmT7ZCyclin-dependent kinase 22.7.11.220.470
4qmlANPSerine/threonine-protein kinase 242.7.11.10.470
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.470
4zhxC1V5'-AMP-activated protein kinase catalytic subunit alpha-2/0.470
4zhxC1V5'-AMP-activated protein kinase subunit beta-1/0.470
3apfBMWPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.469
3q60ATPRhoptry protein 5B/0.469
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.469
1jnkANPMitogen-activated protein kinase 102.7.11.240.468
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.468
3cgcCOACoenzyme A disulfide reductase/0.468
3havATPAminoglycoside phosphotransferase/0.468
3qc9ADPRhodopsin kinase/0.468
3qd03Q43-phosphoinositide-dependent protein kinase 12.7.11.10.468
3zw3ZW3Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.468
4bfmANPMaternal embryonic leucine zipper kinase2.7.11.10.468
4ku2MYA3-oxoacyl-[ACP] synthase III/0.468
5dr2ATPAurora kinase A2.7.11.10.468
1dawANPCasein kinase II subunit alpha2.7.11.10.467
1unhIXMCyclin-dependent-like kinase 52.7.11.10.467
2a4zBYMPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.467
3c50ADPRhodopsin kinase/0.467
3qaqQAQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.467
3qd33Q53-phosphoinositide-dependent protein kinase 12.7.11.10.467
4fjz4FJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.467
2chz093Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.466
2uzbC75Cyclin-dependent kinase 22.7.11.220.466
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.466
3gu7ADPDeath-associated protein kinase 12.7.11.10.466
3i4bZ48Glycogen synthase kinase-3 beta2.7.11.260.466
3t99ADPInositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2/0.466
4bwxAGSPAB-dependent poly(A)-specific ribonuclease subunit pan3/0.466
4jia1K3Tyrosine-protein kinase JAK2/0.466
4wh3ATPN-acetylhexosamine 1-kinase2.7.1.1620.466
5c03AGSNon-receptor tyrosine-protein kinase TYK22.7.10.20.466
5e8xSTUTGF-beta receptor type-12.7.11.300.466
2j0m4STFocal adhesion kinase 12.7.10.20.465
3a8tATPAdenylate isopentenyltransferase/0.465
3tkh07SSerine/threonine-protein kinase Chk12.7.11.10.465
4otpADPSerine/threonine-protein kinase RIO12.7.11.10.465
4qnyANPMitogen activated protein kinase, putative/0.465
2vgpAD6Aurora kinase B-A2.7.11.10.464
2vqdAP2Biotin carboxylase6.3.4.140.464
2yefANPHeat shock protein HSP 90-alpha/0.464
3datMTXDihydrofolate reductase/0.464
3hkoANPCalcium/calmodulin-dependent protein kinase with a kinase domain and 2 calmodulin-like EF hands/0.464
4l3l5FIRibosomal protein S6 kinase beta-12.7.11.10.464
4o95245Cytokinin dehydrogenase 4/0.464
5aabVGHALK tyrosine kinase receptor2.7.10.10.464
1ad5ANPTyrosine-protein kinase HCK2.7.10.20.463
2b9jADPMitogen-activated protein kinase FUS32.7.11.240.463
3t8oATPRhodopsin kinase/0.463
4b7p9UNHeat shock protein HSP 90-alpha/0.463
4c4g7RODual specificity protein kinase TTK2.7.12.10.463
4ftiH7KSerine/threonine-protein kinase Chk12.7.11.10.463
4fzvSAM5-methylcytosine rRNA methyltransferase NSUN42.1.10.463
4k8aK8AFocal adhesion kinase 12.7.10.20.463
4qmxH8HSerine/threonine-protein kinase 242.7.11.10.463
5ackATP3-phosphoinositide-dependent protein kinase 12.7.11.10.463
1e8wQUEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.462
1ig1ANPDeath-associated protein kinase 12.7.11.10.462
1zarADPRIO-type serine/threonine-protein kinase Rio22.7.11.10.462
2xbjXBJSerine/threonine-protein kinase Chk22.7.11.10.462
3sh25DRDihydrofolate reductase1.5.1.30.462
4ic7ANPMitogen-activated protein kinase 72.7.11.240.462
4s33ANPMitogen-activated protein kinase 12.7.11.240.462
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.461
3gu5ANPDeath-associated protein kinase 12.7.11.10.461
4krcAGSCyclin-dependent protein kinase PHO852.7.11.220.461
4lfiGNPCasein kinase II subunit alpha2.7.11.10.461
4r8qADPMitotic checkpoint serine/threonine-protein kinase BUB12.7.11.10.461
5iqdGNPBifunctional AAC/APH2.3.10.461
1jdbADPCarbamoyl-phosphate synthase large chain/0.460
2cn8DBQSerine/threonine-protein kinase Chk22.7.11.10.460
3eem53VUncharacterized protein/0.460
3mtfA3FActivin receptor type-12.7.11.300.460
4c4h7RODual specificity protein kinase TTK2.7.12.10.460
4ezj0SCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.460
4i4e1BQFocal adhesion kinase 12.7.10.20.460
4lrjANPUncharacterized protein/0.460
5aaaVGHALK tyrosine kinase receptor2.7.10.10.460
1j7lADPAminoglycoside 3'-phosphotransferase2.7.1.950.459
1pkgADPMast/stem cell growth factor receptor Kit2.7.10.10.459
2c5nCK8Cyclin-dependent kinase 22.7.11.220.459
2ojj82AMitogen-activated protein kinase 12.7.11.240.459
2x1nX1NCyclin-dependent kinase 22.7.11.220.459
3s2a2NQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.459
3wowANPCasein kinase II subunit alpha2.7.11.10.459
4gmy0X5Tyrosine-protein kinase JAK2/0.459
4hge15VTyrosine-protein kinase JAK2/0.459
4u9zCOAAlpha-tubulin N-acetyltransferase 1/0.459
5e8ySTUTGF-beta receptor type-22.7.11.300.459
1iyzNDPProbable quinone oxidoreductase/0.458
2chw039Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.458
3cgfJNFMitogen-activated protein kinase 102.7.11.240.458
3lmgANPReceptor tyrosine-protein kinase erbB-32.7.10.10.458
4bcnT9NCyclin-dependent kinase 22.7.11.220.458
4deeADPAurora kinase A2.7.11.10.458
4dk50KOPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.458
4eol1ROCyclin-dependent kinase 22.7.11.220.458
4fv2EK5Mitogen-activated protein kinase 12.7.11.240.458
4xlvACPInsulin receptor2.7.10.10.458
5awmANPStress-activated protein kinase JNK2.7.11.240.458
5dt3ATPAurora kinase A2.7.11.10.458
1ir3ANPInsulin receptor2.7.10.10.457
1jtuLYBThymidylate synthase/0.457
2cchATPCyclin-dependent kinase 22.7.11.220.457
2o1xTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.457
2wqeADPAurora kinase A2.7.11.10.457
2zcePYLPyrrolysine--tRNA ligase/0.457
3hxbBD5Geranylgeranyl transferase type-2 subunit beta2.5.1.600.457
3rv3ADPBiotin carboxylase6.3.4.140.457
3rwpABQ3-phosphoinositide-dependent protein kinase 12.7.11.10.457
3vweCOAAlpha-tubulin N-acetyltransferase 1/0.457
4ezk0SDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.457
4fjyFJYPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.457
4jseQJ2Nitric oxide synthase, brain1.14.13.390.457
4l3j5FIRibosomal protein S6 kinase beta-12.7.11.10.457
5dnrATPAurora kinase A2.7.11.10.457
2bdjHETProto-oncogene tyrosine-protein kinase Src2.7.10.20.456
2p55MRADual specificity mitogen-activated protein kinase kinase 12.7.12.20.456
2pe15173-phosphoinositide-dependent protein kinase 12.7.11.10.456
2yk2YJWHeat shock protein HSP 90-alpha/0.456
3c4zADPRhodopsin kinase/0.456
3s2pPMUCyclin-dependent kinase 22.7.11.220.456
3w0oADPHygromycin-B 4-O-kinase2.7.1.1630.456
4awp99AHeat shock protein HSP 90-alpha/0.456
4jrnANPRhoptry kinase family protein/0.456
4o4eATPKinase/0.456
5drdATPAurora kinase A2.7.11.10.456
1ol7ADPAurora kinase A2.7.11.10.455
1sze173Cytochrome b2, mitochondrial1.1.2.30.455
2xvv9DNSerum albumin/0.455
3jziJZLBiotin carboxylase6.3.4.140.455
3tdvGDPGentamicin resistance protein/0.455
4bgg844Activin receptor type-12.7.11.300.455
4ct2ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.455
4flh14KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.455
4hyu1BKMitogen-activated protein kinase 82.7.11.240.455
4l9i8PRRhodopsin kinase/0.455
4q4cADPInositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2/0.455
1b38ATPCyclin-dependent kinase 22.7.11.220.454
1dayGNPCasein kinase II subunit alpha2.7.11.10.454
1tqpATPRIO-type serine/threonine-protein kinase Rio22.7.11.10.454
1u54ACPActivated CDC42 kinase 1/0.454
1uvrBI83-phosphoinositide-dependent protein kinase 12.7.11.10.454
1xr1ANPSerine/threonine-protein kinase pim-12.7.11.10.454
2fpcSCGStrictosidine synthase4.3.3.20.454
2qo9ANPEphrin type-A receptor 32.7.10.10.454
2qocANPEphrin type-A receptor 32.7.10.10.454
3f69XDRSerine/threonine-protein kinase PknB2.7.11.10.454
3lijANPCalcium/calmodulin dependent protein kinase with a kinase domain and 4 calmodulin like EF hands/0.454
3nrrD16Bifunctional dihydrofolate reductase-thymidylate synthase/0.454
3ztxZTXAurora kinase B-A2.7.11.10.454
4hyh1AMSerine/threonine-protein kinase Chk12.7.11.10.454
1h1wATP3-phosphoinositide-dependent protein kinase 12.7.11.10.453
1oguST8Cyclin-dependent kinase 22.7.11.220.453
1q8yADPSerine/threonine-protein kinase SKY12.7.11.10.453
2bu7TF3[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial2.7.11.20.453
2eklNADD-3-phosphoglycerate dehydrogenase/0.453
3fyvXCFDihydrofolate reductase1.5.1.30.453
3t9eADPInositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2/0.453
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.453
4dit0KDGlycogen synthase kinase-3 beta2.7.11.260.453
4eor4SPCyclin-dependent kinase 22.7.11.220.453
4izy1J2Mitogen-activated protein kinase 82.7.11.240.453
4o0rX4ZSerine/threonine-protein kinase PAK 12.7.11.10.453
1okySTU3-phosphoinositide-dependent protein kinase 12.7.11.10.452
2bfyH1NAurora kinase B-A2.7.11.10.452
2i4jDRJPeroxisome proliferator-activated receptor gamma/0.452
2jizADPATP synthase subunit beta, mitochondrial3.6.3.140.452
3lj3WYEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.452
3mqe416Prostaglandin G/H synthase 21.14.99.10.452
3ofm4B0Casein kinase II subunit alpha'2.7.11.10.452
3ortAGSSerine/threonine protein kinase/0.452
3qcmNXWReceptor-type tyrosine-protein phosphatase gamma3.1.3.480.452
3qwkX62Cyclin-dependent kinase 22.7.11.220.452
3rpr25ZCyclin-dependent kinase 22.7.11.220.452
4ele31IDihydrofolate reductase/0.452
4fg7ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.452
5iqaGNPBifunctional AAC/APH2.3.10.452
1hckATPCyclin-dependent kinase 22.7.11.220.451
1z5mLI83-phosphoinositide-dependent protein kinase 12.7.11.10.451
2biyATP3-phosphoinositide-dependent protein kinase 12.7.11.10.451
2ghmLICMitogen-activated protein kinase 14/0.451
3nunJMZ3-phosphoinositide-dependent protein kinase 12.7.11.10.451
3ormAGSSerine/threonine protein kinase/0.451
3qcq3Q03-phosphoinositide-dependent protein kinase 12.7.11.10.451
3qk0QK0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.451
3r9nZ68Cyclin-dependent kinase 22.7.11.220.451
3vs2VSBTyrosine-protein kinase HCK2.7.10.20.451
3w0sANPHygromycin-B 4-O-kinase2.7.1.1630.451
3zxtACPDeath-associated protein kinase 12.7.11.10.451
4anv751Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.451
4b6cB5UDNA gyrase subunit B/0.451
4bl5GFBGDP-L-fucose synthase1.1.1.2710.451
4egh0OYHeat shock protein HSP 90-alpha/0.451
4enyJ19Serine/threonine-protein kinase pim-12.7.11.10.451
4eooATPCyclin-dependent kinase 22.7.11.220.451
4hle17VPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.451
4nm0ADPGlycogen synthase kinase-3 beta2.7.11.260.451
1kzjCB3Thymidylate synthase/0.450
1zthADPRIO-type serine/threonine-protein kinase Rio12.7.11.10.450
2pe24643-phosphoinositide-dependent protein kinase 12.7.11.10.450
2pulACPMethylthioribose kinase2.7.1.1000.450
2w4kADPDeath-associated protein kinase 12.7.11.10.450
3ambVX6cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.450
3b9lAZZSerum albumin/0.450
3ibdCPZCytochrome P450 2B61.14.130.450
3nizADPCdc2-like CDK2/CDC28 like protein kinase/0.450
3zvvXAZPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.450
4bi0Z0WDual specificity protein kinase TTK2.7.12.10.450
4ezl0SEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.450
4gb90WRPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.450
4i3zADPCyclin-dependent kinase 22.7.11.220.450
4j97ACPFibroblast growth factor receptor 2/0.450
4jqeANPCasein kinase II subunit alpha2.7.11.10.450
5iqiGNPBifunctional AAC/APH2.3.10.450
1bvrTHTEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.449
1i44ACPInsulin receptor2.7.10.10.449
1pyxANPGlycogen synthase kinase-3 beta2.7.11.260.449
1yqj6NPMitogen-activated protein kinase 14/0.449
1zaoATPRIO-type serine/threonine-protein kinase Rio22.7.11.10.449
2bujSTUSerine/threonine-protein kinase 16/0.449
2jfhLK1UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.449
2py3ACPFibroblast growth factor receptor 2/0.449
2vtqLZACyclin-dependent kinase 22.7.11.220.449
2yitYITSerine/threonine-protein kinase Chk22.7.11.10.449
3axwTIDCasein kinase II subunit alpha2.7.11.10.449
3cgbCOACoenzyme A disulfide reductase/0.449
3kp4MIITranscriptional regulator TcaR/0.449
4bcqTJFCyclin-dependent kinase 22.7.11.220.449
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.10.449
4lv8ADPRhoptry protein 5 C/0.449
4z34ON7Lysophosphatidic acid receptor 1/0.449
2bycFMNBlue-light receptor of the BLUF-family/0.448
2gfdRDAEndoplasmin/0.448
2r7b2533-phosphoinositide-dependent protein kinase 12.7.11.10.448
2xuuADPDeath-associated protein kinase 12.7.11.10.448
2zb3NDPProstaglandin reductase 21.3.1.480.448
3a7jADPSerine/threonine-protein kinase 242.7.11.10.448
3g8dADPBiotin carboxylase6.3.4.140.448
3hrfATP3-phosphoinositide-dependent protein kinase 12.7.11.10.448
3i60E86Mitogen-activated protein kinase 12.7.11.240.448
3sruQ26Dihydrofolate reductase1.5.1.30.448
4e1z0MXNon-receptor tyrosine-protein kinase TYK22.7.10.20.448
4g1wG1WMitogen-activated protein kinase 82.7.11.240.448
4kz01UJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.448
4l23X6KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform/0.448
4xcjADPHeat shock cognate 90 kDa protein/0.448
4y0xADPSerine/threonine-protein kinase PknG2.7.11.10.448
5ap7SVEDual specificity protein kinase TTK2.7.12.10.448
1j39UPGDNA beta-glucosyltransferase/0.447
2i4pDRHPeroxisome proliferator-activated receptor gamma/0.447
2prh238Dihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.447
2r3gSC9Cyclin-dependent kinase 22.7.11.220.447
2wmsZYSSerine/threonine-protein kinase Chk12.7.11.10.447
2xvdAS6Ephrin type-B receptor 42.7.10.10.447
2z7qACPRibosomal protein S6 kinase alpha-12.7.11.10.447
3ekrPY9Heat shock protein HSP 90-alpha/0.447
3rkb12ZCyclin-dependent kinase 22.7.11.220.447
3sgv2BJDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.447
4aw1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.447
4fcr0TMHeat shock protein HSP 90-alpha/0.447
4hyp1A1DNA gyrase subunit B/0.447
4xhgADPUncharacterized protein/0.447
5ca0ACPTubulin tyrosine ligase/0.447
5dq8FLFTranscriptional enhancer factor TEF-4/0.447
1kgjFL8Transthyretin/0.446
1ol5ADPAurora kinase A2.7.11.10.446
1pnvTYDdTDP-epi-vancosaminyltransferase2.4.1.3110.446
2b9fADPMitogen-activated protein kinase FUS32.7.11.240.446
2izrBRKCasein kinase I isoform gamma-32.7.11.10.446
2v92ATP5'-AMP-activated protein kinase subunit gamma-1/0.446
2wmuZYUSerine/threonine-protein kinase Chk12.7.11.10.446
2xk9XK9Serine/threonine-protein kinase Chk22.7.11.10.446
3a8wATPProtein kinase C iota type2.7.11.130.446
3cd57HI3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.340.446
3igoANPCalmodulin-domain protein kinase 1, putative/0.446
3k974CDHeat shock protein HSP 90-alpha/0.446
3mnrSD1Heat shock protein HSP 90-alpha/0.446
3plsANPMacrophage-stimulating protein receptor2.7.10.10.446
3qlxQLRUncharacterized protein/0.446
3r71X86Cyclin-dependent kinase 22.7.11.220.446
3t9aANPInositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2/0.446
3tm0ANPAminoglycoside 3'-phosphotransferase2.7.1.950.446
4b99R4LMitogen-activated protein kinase 72.7.11.240.446
4bhzZ0BDual specificity protein kinase TTK2.7.12.10.446
4ekkANPRAC-alpha serine/threonine-protein kinase2.7.11.10.446
4fswHK6Serine/threonine-protein kinase Chk12.7.11.10.446
4ftaH5KSerine/threonine-protein kinase Chk12.7.11.10.446
4fz70VHTyrosine-protein kinase SYK2.7.10.20.446
1h1r6CPCyclin-dependent kinase 22.7.11.220.445
1uy7PU4Heat shock protein HSP 90-alpha/0.445
1w1rZEACytokinin dehydrogenase 11.5.99.120.445
1ywrLI9Mitogen-activated protein kinase 14/0.445
2atiIHUGlycogen phosphorylase, liver form2.4.1.10.445
2c5yMTWCyclin-dependent kinase 22.7.11.220.445
2cgu3A3Serine/threonine-protein kinase Chk12.7.11.10.445
2pdtFADVivid PAS protein VVD/0.445
2wpa889Cyclin-dependent kinase 22.7.11.220.445
3hrcATP3-phosphoinositide-dependent protein kinase 12.7.11.10.445
3lu7IPXSerum albumin/0.445
3rlq3RQHeat shock protein HSP 90-alpha/0.445
4dh5ADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.445
4eajATP5'-AMP-activated protein kinase subunit gamma-1/0.445
4f1sF1SPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
1h0vUN4Cyclin-dependent kinase 22.7.11.220.444
1m0wANPGlutathione synthetase6.3.2.30.444
1mruAGSSerine/threonine-protein kinase PknB2.7.11.10.444
1pkdUCNCyclin-dependent kinase 22.7.11.220.444
1x8b824Wee1-like protein kinase2.7.10.20.444
2b51UTPRNA editing complex protein MP57/0.444
2j7t274Serine/threonine-protein kinase 102.7.11.10.444
2r3q5SCCyclin-dependent kinase 22.7.11.220.444
2xs0ANPMitogen-activated protein kinase 82.7.11.240.444
3bv3P39Mitogen-activated protein kinase 14/0.444
3cgdCOACoenzyme A disulfide reductase/0.444
3mdmFJZCholesterol 24-hydroxylase/0.444
4ax8ADPO-antigen chain terminator bifunctional methyltransferase/kinase WbdD/0.444
4e4l0NHTyrosine-protein kinase JAK1/0.444
4k33ACPFibroblast growth factor receptor 32.7.10.10.444
5c1oANPD-alanine--D-alanine ligase/0.444
5eg3ACPFibroblast growth factor receptor 2/0.444
1ay0TPPTransketolase 12.2.1.10.443
1e9hINRCyclin-dependent kinase 22.7.11.220.443
1q97ATPSerine/threonine-protein kinase SKY12.7.11.10.443
1zeoC01Peroxisome proliferator-activated receptor gamma/0.443
2byh2D7Heat shock protein HSP 90-alpha/0.443
2ijmATPFocal adhesion kinase 12.7.10.20.443
2p0aANPSynapsin-3/0.443
2v4lABJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
2x4f16XMyosin light chain kinase family member 42.7.11.10.443
2ycrHCWSerine/threonine-protein kinase Chk22.7.11.10.443
2ye42FYHeat shock protein HSP 90-alpha/0.443
3cgoJNOMitogen-activated protein kinase 102.7.11.240.443
4axdANPInositol-pentakisphosphate 2-kinase2.7.1.1580.443
4b8mVX6Aurora kinase B-A2.7.11.10.443
4fl1ANPTyrosine-protein kinase SYK2.7.10.20.443
4ks7X4ZSerine/threonine-protein kinase PAK 62.7.11.10.443
4utdACPAurora kinase A2.7.11.10.443
5cnnANPEpidermal growth factor receptor2.7.10.10.443
5cyqT27Gag-Pol polyprotein2.7.7.490.443
5djtFMNNPH1-2/0.443
1om1IQACasein kinase II subunit alpha2.7.11.10.442
2br1PFPSerine/threonine-protein kinase Chk12.7.11.10.442
2c68CT6Cyclin-dependent kinase 22.7.11.220.442
2ckeIQUDeath-associated protein kinase 2/0.442
2pupADPMethylthioribose kinase2.7.1.1000.442
2r1rTTPRibonucleoside-diphosphate reductase 1 subunit alpha1.17.4.10.442
2y4lGDPUncharacterized protein/0.442
2yac937Serine/threonine-protein kinase PLK12.7.11.210.442
3dauMTXDihydrofolate reductase1.5.1.30.442
3frfXCFDihydrofolate reductase1.5.1.30.442
3sa16DRDihydrofolate reductase/0.442
3sc13S13-phosphoinositide-dependent protein kinase 12.7.11.10.442
3ta2ATPNitrogen regulatory protein P-II (GlnB-3)/0.442
4c4f7CEDual specificity protein kinase TTK2.7.12.10.442
4ffrATPUncharacterized protein/0.442
4fk3325Serine/threonine-protein kinase B-raf2.7.11.10.442
4fmqANPMitogen-activated protein kinase 12.7.11.240.442
4hkfACOAlpha-tubulin N-acetyltransferase 1/0.442
4jloADPAdenylate kinase/0.442
5av3KMPDeath-associated protein kinase 12.7.11.10.442
1finATPCyclin-dependent kinase 22.7.11.220.441
1jpaANPEphrin type-B receptor 22.7.10.10.441
1nbmADPATP synthase subunit beta, mitochondrial3.6.3.140.441
1uu8BI13-phosphoinositide-dependent protein kinase 12.7.11.10.441
2b9wFADPutative aminooxidase/0.441
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
2e9zUTPGenome polyprotein/0.441
2etm7PYFocal adhesion kinase 12.7.10.20.441
2gn8NAPUDP-N-acetylglucosamine 4,6-dehydratase (inverting)4.2.1.1150.441
2i40BLZCyclin-dependent kinase 22.7.11.220.441
2o2u738Mitogen-activated protein kinase 102.7.11.240.441
2p33J07Mitogen-activated protein kinase 102.7.11.240.441
2r26CMCCitrate synthase2.3.3.160.441
2ykeYKEHeat shock protein HSP 90-alpha/0.441
3qwjX6ACyclin-dependent kinase 22.7.11.220.441
3qx2X63Cyclin-dependent kinase 22.7.11.220.441
4bbfO19Tyrosine-protein kinase JAK2/0.441
4f1oACPProbable serine/threonine-protein kinase roco42.7.11.10.441
4fx360KCyclin-dependent kinase 22.7.11.220.441
4hhdFMNPhototropin-12.7.11.10.441
4xw5ATPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.441
1joaFADNADH peroxidase1.11.1.10.440
1oitHDTCyclin-dependent kinase 22.7.11.220.440
1pk8ATPSynapsin-1/0.440
1rt5UC2Gag-Pol polyprotein2.7.7.490.440
1u4dDBQActivated CDC42 kinase 1/0.440
1vyzN5BCyclin-dependent kinase 22.7.11.220.440
2az3CDPNucleoside diphosphate kinase/0.440
2c3lIDZSerine/threonine-protein kinase Chk12.7.11.10.440
2dr3ADPUPF0273 protein PH0284/0.440
2e9v85ASerine/threonine-protein kinase Chk12.7.11.10.440
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.440
2ouyCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.440
2yn8STUEphrin type-B receptor 42.7.10.10.440
3c4xATPRhodopsin kinase/0.440
3ft8MOJHeat shock protein HSP 90-alpha/0.440
3qd43Q63-phosphoinositide-dependent protein kinase 12.7.11.10.440
3qly55VUncharacterized protein/0.440
4bl1ANPMaternal embryonic leucine zipper kinase2.7.11.10.440
4mxxDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.440