Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3vs3 | VSE | Tyrosine-protein kinase HCK | 2.7.10.2 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3vs3 | VSE | Tyrosine-protein kinase HCK | 2.7.10.2 | 1.000 | |
| 3vrz | VRZ | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.649 | |
| 3vry | B43 | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.646 | |
| 3vs5 | VSG | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.644 | |
| 2h8h | H8H | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.643 | |
| 3vs0 | VS0 | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.635 | |
| 1qcf | PP1 | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.628 | |
| 3vs2 | VSB | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.625 | |
| 3vs7 | KS1 | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.621 | |
| 3vs4 | VSF | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.619 | |
| 3vs6 | VSH | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.616 | |
| 2c0t | L3G | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.611 | |
| 4k11 | 0J9 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.610 | |
| 3bbt | FMM | Receptor tyrosine-protein kinase erbB-4 | 2.7.10.1 | 0.605 | |
| 2hk5 | 1BM | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.598 | |
| 3vs1 | VSA | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.592 | |
| 2c0i | L1G | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.587 | |
| 2c0o | L2G | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.587 | |
| 3qlf | PD5 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.587 | |
| 2bdf | 24A | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.586 | |
| 3w33 | W19 | Epidermal growth factor receptor | 2.7.10.1 | 0.575 | |
| 3b8r | 887 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.571 | |
| 4id7 | 1G0 | Activated CDC42 kinase 1 | / | 0.571 | |
| 4dgg | I76 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.570 | |
| 3w2s | W2R | Epidermal growth factor receptor | 2.7.10.1 | 0.563 | |
| 1yol | S03 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.561 | |
| 3poz | 03P | Epidermal growth factor receptor | 2.7.10.1 | 0.561 | |
| 1xkk | FMM | Epidermal growth factor receptor | 2.7.10.1 | 0.560 | |
| 2zm1 | KSF | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.559 | |
| 2bdj | HET | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.548 | |
| 1qpj | STU | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.547 | |
| 4i22 | IRE | Epidermal growth factor receptor | 2.7.10.1 | 0.544 | |
| 1qpd | STU | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.540 | |
| 2zv9 | PP2 | Tyrosine-protein kinase Lyn | 2.7.10.2 | 0.540 | |
| 5ajq | DB8 | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.540 | |
| 1ad5 | ANP | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.539 | |
| 4mxo | DB8 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.539 | |
| 3ue4 | DB8 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.536 | |
| 2zva | 1N1 | Tyrosine-protein kinase Lyn | 2.7.10.2 | 0.535 | |
| 3b2w | 9NH | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.535 | |
| 4gk2 | L66 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.535 | |
| 2of2 | 547 | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.534 | |
| 4hjo | AQ4 | Epidermal growth factor receptor | 2.7.10.1 | 0.534 | |
| 4otw | DB8 | Receptor tyrosine-protein kinase erbB-3 | 2.7.10.1 | 0.534 | |
| 4lgg | VGG | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.531 | |
| 1m17 | AQ4 | Epidermal growth factor receptor | 2.7.10.1 | 0.530 | |
| 3w32 | W32 | Epidermal growth factor receptor | 2.7.10.1 | 0.530 | |
| 4riy | ADP | Epidermal growth factor receptor | 2.7.10.1 | 0.530 | |
| 2dq7 | STU | Tyrosine-protein kinase Fyn | 2.7.10.2 | 0.529 | |
| 4lgh | 0JN | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.529 | |
| 3qlg | 1N1 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.527 | |
| 4xey | 1N1 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.527 | |
| 4yuq | KS1 | Calmodulin-like domain protein kinase | / | 0.527 | |
| 1byg | STU | Tyrosine-protein kinase CSK | / | 0.526 | |
| 4gk3 | L87 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.526 | |
| 4gk4 | L90 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.525 | |
| 3vjo | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.522 | |
| 4nka | 2K7 | Fibroblast growth factor receptor 1 | / | 0.522 | |
| 1u4d | DBQ | Activated CDC42 kinase 1 | / | 0.521 | |
| 1vjy | 460 | TGF-beta receptor type-1 | 2.7.11.30 | 0.520 | |
| 2eb3 | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.520 | |
| 4wkq | IRE | Epidermal growth factor receptor | 2.7.10.1 | 0.519 | |
| 3gxl | QIG | TGF-beta receptor type-1 | 2.7.11.30 | 0.518 | |
| 2p2h | 994 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.517 | |
| 2wot | ZZG | TGF-beta receptor type-1 | 2.7.11.30 | 0.517 | |
| 4xli | 1N1 | Abelson tyrosine-protein kinase 2 | 2.7.10.2 | 0.516 | |
| 1rw8 | 580 | TGF-beta receptor type-1 | 2.7.11.30 | 0.515 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.515 | |
| 2vwu | 7X1 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.515 | |
| 4jr3 | KJR | Epidermal growth factor receptor | 2.7.10.1 | 0.515 | |
| 2qoc | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.514 | |
| 4mxx | DB8 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.514 | |
| 4nk9 | 2K5 | Fibroblast growth factor receptor 1 | / | 0.514 | |
| 4fic | 0UL | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.513 | |
| 2c6e | HPM | Aurora kinase A | 2.7.11.1 | 0.512 | |
| 3a4o | STU | Tyrosine-protein kinase Lyn | 2.7.10.2 | 0.511 | |
| 3ac5 | KZM | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.511 | |
| 4mxy | DB8 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.511 | |
| 4mxz | DB8 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.511 | |
| 4jq8 | KJ8 | Epidermal growth factor receptor | 2.7.10.1 | 0.510 | |
| 4l7s | G7K | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.510 | |
| 5e8x | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.510 | |
| 1u54 | ACP | Activated CDC42 kinase 1 | / | 0.509 | |
| 4hvh | 19R | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.509 | |
| 2qoq | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.507 | |
| 4i23 | 1C9 | Epidermal growth factor receptor | 2.7.10.1 | 0.507 | |
| 4kiq | 1RA | Mitogen-activated protein kinase 14 | / | 0.506 | |
| 3zew | STU | Ephrin type-B receptor 4 | 2.7.10.1 | 0.505 | |
| 4g2f | C07 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.505 | |
| 2py3 | ACP | Fibroblast growth factor receptor 2 | / | 0.504 | |
| 2vwx | 7X4 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.504 | |
| 4c3f | 7KW | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.504 | |
| 1y57 | MPZ | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.503 | |
| 2itq | ITQ | Epidermal growth factor receptor | 2.7.10.1 | 0.503 | |
| 3lcd | BDY | Macrophage colony-stimulating factor 1 receptor | 2.7.10.1 | 0.503 | |
| 5aaa | VGH | ALK tyrosine kinase receptor | 2.7.10.1 | 0.503 | |
| 2itn | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.502 | |
| 2itt | AEE | Epidermal growth factor receptor | 2.7.10.1 | 0.502 | |
| 2w2l | NAD | D-mandelate dehydrogenase | / | 0.502 | |
| 3hmm | 855 | TGF-beta receptor type-1 | 2.7.11.30 | 0.502 | |
| 4jq7 | KJQ | Epidermal growth factor receptor | 2.7.10.1 | 0.502 | |
| 4nks | 2M2 | Fibroblast growth factor receptor 1 | / | 0.502 | |
| 2of4 | 979 | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.501 | |
| 2xvd | AS6 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.501 | |
| 2ivu | ZD6 | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.500 | |
| 2xyu | Q9G | Ephrin type-A receptor 4 | 2.7.10.1 | 0.500 | |
| 2vwz | 7X6 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.499 | |
| 3c7q | XIN | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.499 | |
| 2vwy | 7X5 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.498 | |
| 2y6o | 1N1 | Ephrin type-A receptor 4 | 2.7.10.1 | 0.498 | |
| 4dfl | 0K0 | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.498 | |
| 2exc | JNK | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.497 | |
| 4bb4 | 32W | Ephrin type-B receptor 4 | 2.7.10.1 | 0.497 | |
| 5amn | DTQ | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.497 | |
| 1qpe | PP2 | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.496 | |
| 2gs7 | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.496 | |
| 2yn8 | STU | Ephrin type-B receptor 4 | 2.7.10.1 | 0.496 | |
| 3l8p | 0CE | Angiopoietin-1 receptor | 2.7.10.1 | 0.496 | |
| 3s4q | NK0 | Mitogen-activated protein kinase 14 | / | 0.496 | |
| 4btk | DTQ | Tau-tubulin kinase 1 | 2.7.11.1 | 0.496 | |
| 4hvi | 19S | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.496 | |
| 1ie4 | T44 | Transthyretin | / | 0.495 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.495 | |
| 2itz | IRE | Epidermal growth factor receptor | 2.7.10.1 | 0.495 | |
| 2ycq | UPX | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.495 | |
| 3ac2 | KSE | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.495 | |
| 3ad6 | KSC | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.495 | |
| 3el8 | PD5 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.495 | |
| 3gub | GUB | Death-associated protein kinase 1 | 2.7.11.1 | 0.495 | |
| 4c62 | XWW | Tyrosine-protein kinase JAK2 | / | 0.495 | |
| 5e8w | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.495 | |
| 2fb8 | 215 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.494 | |
| 2ivv | PP1 | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.494 | |
| 3cjg | KIM | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.494 | |
| 3w2r | W2R | Epidermal growth factor receptor | 2.7.10.1 | 0.494 | |
| 4l52 | 1UL | Mitogen-activated protein kinase kinase kinase 7 | 2.7.11.25 | 0.494 | |
| 2gcd | STU | Serine/threonine-protein kinase TAO2 | 2.7.11.1 | 0.493 | |
| 2om9 | AJA | Peroxisome proliferator-activated receptor gamma | / | 0.493 | |
| 3uvq | FS8 | Mitogen-activated protein kinase 14 | / | 0.493 | |
| 4hvg | 19Q | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.493 | |
| 3gc9 | B45 | Mitogen-activated protein kinase 11 | 2.7.11.24 | 0.492 | |
| 3oom | 507 | Activin receptor type-1 | 2.7.11.30 | 0.492 | |
| 4ks8 | B49 | Serine/threonine-protein kinase PAK 6 | 2.7.11.1 | 0.492 | |
| 2cdz | 23D | Serine/threonine-protein kinase PAK 4 | 2.7.11.1 | 0.491 | |
| 2vx0 | 7X7 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.491 | |
| 3js2 | VM1 | Fibroblast growth factor receptor 1 | / | 0.491 | |
| 3lj3 | WYE | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.491 | |
| 4j97 | ACP | Fibroblast growth factor receptor 2 | / | 0.491 | |
| 3ac3 | KSH | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.489 | |
| 4bf2 | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.489 | |
| 4fk3 | 325 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.489 | |
| 2yit | YIT | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.488 | |
| 2x2l | X2L | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.487 | |
| 2x2m | X2M | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.487 | |
| 2xk9 | XK9 | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.487 | |
| 3ttj | JBI | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.487 | |
| 3v8w | 0G2 | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.487 | |
| 4cki | ADN | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.487 | |
| 4f64 | 0S8 | Fibroblast growth factor receptor 1 | / | 0.487 | |
| 2hen | ADP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.486 | |
| 2wou | ZZF | TGF-beta receptor type-1 | 2.7.11.30 | 0.486 | |
| 2zyb | KSL | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.486 | |
| 3ml8 | ML8 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.486 | |
| 3ori | AGS | Serine/threonine protein kinase | / | 0.486 | |
| 4jia | 1K3 | Tyrosine-protein kinase JAK2 | / | 0.486 | |
| 4yzc | STU | Serine/threonine-protein kinase/endoribonuclease IRE1 | 2.7.11.1 | 0.486 | |
| 4g3e | 0WC | Mitogen-activated protein kinase kinase kinase 14 | 2.7.11.25 | 0.484 | |
| 4jlc | SU6 | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.484 | |
| 1py5 | PY1 | TGF-beta receptor type-1 | 2.7.11.30 | 0.483 | |
| 2vww | 7X2 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.483 | |
| 2xp2 | VGH | ALK tyrosine kinase receptor | 2.7.10.1 | 0.483 | |
| 4eqc | XR1 | Serine/threonine-protein kinase PAK 1 | 2.7.11.1 | 0.483 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.482 | |
| 3fsk | RO6 | Mitogen-activated protein kinase 14 | / | 0.481 | |
| 4dym | IYZ | Activin receptor type-1 | 2.7.11.30 | 0.481 | |
| 2pzp | ACP | Fibroblast growth factor receptor 2 | / | 0.480 | |
| 4jrv | KJV | Epidermal growth factor receptor | 2.7.10.1 | 0.480 | |
| 4u97 | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.480 | |
| 5hes | 032 | Mitogen-activated protein kinase kinase kinase 20 | 2.7.11.25 | 0.479 | |
| 4bid | IE8 | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.478 | |
| 3ncg | BK1 | Calmodulin-domain protein kinase 1, putative | / | 0.477 | |
| 3zdi | UGJ | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.477 | |
| 4aot | GW8 | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.477 | |
| 4k1b | 1OC | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.477 | |
| 1dxo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.476 | |
| 4c58 | 824 | Cyclin-G-associated kinase | 2.7.11.1 | 0.476 | |
| 4fr4 | STU | Serine/threonine-protein kinase 32A | 2.7.11.1 | 0.476 | |
| 2fgi | PD1 | Fibroblast growth factor receptor 1 | / | 0.475 | |
| 2itp | AEE | Epidermal growth factor receptor | 2.7.10.1 | 0.475 | |
| 2vx1 | 7X8 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.475 | |
| 4mcv | 29K | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.475 | |
| 2itv | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.474 | |
| 2yfx | VGH | ALK tyrosine kinase receptor | 2.7.10.1 | 0.474 | |
| 2yiq | YIQ | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.474 | |
| 3qaq | QAQ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.474 | |
| 3w18 | N13 | Aurora kinase A | 2.7.11.1 | 0.474 | |
| 4fst | HK4 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.474 | |
| 2itx | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.473 | |
| 3say | OFT | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.473 | |
| 3tti | KBI | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.473 | |
| 4gmy | 0X5 | Tyrosine-protein kinase JAK2 | / | 0.473 | |
| 4kip | 1R9 | Mitogen-activated protein kinase 14 | / | 0.473 | |
| 1zyj | BI5 | Mitogen-activated protein kinase 14 | / | 0.472 | |
| 2o65 | MYF | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.472 | |
| 2qo7 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.472 | |
| 2zm4 | KSM | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.472 | |
| 4oav | ACP | 2-5A-dependent ribonuclease | 3.1.26 | 0.472 | |
| 4wo5 | 324 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.472 | |
| 1pn3 | TYD | dTDP-epi-vancosaminyltransferase | 2.4.1.311 | 0.471 | |
| 2pmd | GNP | Translation initiation factor 2 subunit gamma | / | 0.471 | |
| 2x2k | X2K | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.471 | |
| 2ycr | HCW | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.471 | |
| 4bc6 | XZN | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.471 | |
| 4ftm | 1HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.471 | |
| 4idv | 13V | Mitogen-activated protein kinase kinase kinase 14 | 2.7.11.25 | 0.471 | |
| 2y98 | MIV | Mycinamicin IV hydroxylase/epoxidase | / | 0.470 | |
| 3f69 | XDR | Serine/threonine-protein kinase PknB | 2.7.11.1 | 0.470 | |
| 3inm | NDP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.470 | |
| 4gfo | 0X2 | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.470 | |
| 4m15 | ADP | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.470 | |
| 1d7y | FAD | Ferredoxin reductase | / | 0.469 | |
| 2h96 | 893 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.469 | |
| 2i1m | 5CN | Macrophage colony-stimulating factor 1 receptor | 2.7.10.1 | 0.469 | |
| 3a60 | STU | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.469 | |
| 3l8x | N4D | Mitogen-activated protein kinase 14 | / | 0.469 | |
| 4ans | VGH | ALK tyrosine kinase receptor | 2.7.10.1 | 0.469 | |
| 4aw5 | 30K | Ephrin type-B receptor 4 | 2.7.10.1 | 0.469 | |
| 4c4g | 7RO | Dual specificity protein kinase TTK | 2.7.12.1 | 0.469 | |
| 4ic7 | ANP | Mitogen-activated protein kinase 7 | 2.7.11.24 | 0.469 | |
| 4zse | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.469 | |
| 1agw | SU2 | Fibroblast growth factor receptor 1 | / | 0.468 | |
| 1e90 | MYC | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.468 | |
| 2itu | ITQ | Epidermal growth factor receptor | 2.7.10.1 | 0.468 | |
| 3dxj | NE6 | DNA-directed RNA polymerase subunit beta | / | 0.468 | |
| 3dxj | NE6 | DNA-directed RNA polymerase subunit beta' | / | 0.468 | |
| 3ocg | OCG | Mitogen-activated protein kinase 14 | / | 0.468 | |
| 4acc | 7YG | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.468 | |
| 4pd6 | URI | Nucleoside permease | / | 0.468 | |
| 2itw | ITQ | Epidermal growth factor receptor | 2.7.10.1 | 0.467 | |
| 3aox | EMH | ALK tyrosine kinase receptor | 2.7.10.1 | 0.467 | |
| 3cyl | VIT | Basic phospholipase A2 homolog piratoxin-2 | / | 0.467 | |
| 3dtc | VIN | Mitogen-activated protein kinase kinase kinase 9 | 2.7.11.25 | 0.467 | |
| 3mtf | A3F | Activin receptor type-1 | 2.7.11.30 | 0.467 | |
| 4f9w | LM4 | Mitogen-activated protein kinase 14 | / | 0.467 | |
| 1di9 | MSQ | Mitogen-activated protein kinase 14 | / | 0.466 | |
| 2aaz | CB3 | Thymidylate synthase | 2.1.1.45 | 0.466 | |
| 2izr | BRK | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.466 | |
| 3ac1 | KZI | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.466 | |
| 3bu5 | ATP | Insulin receptor | 2.7.10.1 | 0.466 | |
| 3gb2 | G3B | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.466 | |
| 3mpa | SB2 | Mitogen-activated protein kinase 14 | / | 0.466 | |
| 3ppk | FNI | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.466 | |
| 3q4z | ANP | Serine/threonine-protein kinase PAK 1 | 2.7.11.1 | 0.466 | |
| 4f65 | 0S9 | Fibroblast growth factor receptor 1 | / | 0.466 | |
| 4jvb | 1M0 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.466 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.466 | |
| 5e92 | ANP | TGF-beta receptor type-2 | 2.7.11.30 | 0.466 | |
| 2jn3 | JN3 | Fatty acid-binding protein, liver | / | 0.465 | |
| 2pz5 | ACP | Fibroblast growth factor receptor 2 | / | 0.465 | |
| 3kf7 | L9G | Mitogen-activated protein kinase 14 | / | 0.465 | |
| 4aic | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.465 | |
| 4bib | IEO | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.465 | |
| 4feq | 0T8 | Tyrosine-protein kinase receptor TYRO3 | 2.7.10.1 | 0.465 | |
| 4flh | 14K | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.465 | |
| 4xlv | ACP | Insulin receptor | 2.7.10.1 | 0.465 | |
| 1xr1 | ANP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.464 | |
| 2gtn | LIE | Mitogen-activated protein kinase 14 | / | 0.464 | |
| 2x9f | X9F | Ephrin type-B receptor 4 | 2.7.10.1 | 0.464 | |
| 2zb0 | GK3 | Mitogen-activated protein kinase 14 | / | 0.464 | |
| 4aa4 | QC0 | Mitogen-activated protein kinase 14 | / | 0.464 | |
| 4aw3 | MYV | Mycinamicin IV hydroxylase/epoxidase | / | 0.464 | |
| 4ckj | ADN | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.464 | |
| 4qms | 1N1 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.464 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.463 | |
| 2f4j | VX6 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.463 | |
| 2xa4 | AZ5 | Tyrosine-protein kinase JAK2 | / | 0.463 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.463 | |
| 4a6b | QG8 | Gag-Pol polyprotein | 3.4.23.16 | 0.463 | |
| 4c4h | 7RO | Dual specificity protein kinase TTK | 2.7.12.1 | 0.463 | |
| 4fnz | NZF | ALK tyrosine kinase receptor | 2.7.10.1 | 0.463 | |
| 1pnv | TYD | dTDP-epi-vancosaminyltransferase | 2.4.1.311 | 0.462 | |
| 2cig | 1DG | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 2wmq | ZYQ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.462 | |
| 3fln | 3FN | Mitogen-activated protein kinase 14 | / | 0.462 | |
| 4ezj | 0SC | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.462 | |
| 4gyi | ADP | Uncharacterized protein | / | 0.462 | |
| 4hgs | 15G | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.462 | |
| 2hog | 710 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.461 | |
| 2i0e | PDS | Protein kinase C beta type | 2.7.11.13 | 0.461 | |
| 3uvp | 048 | Mitogen-activated protein kinase 14 | / | 0.461 | |
| 4c02 | TAK | Activin receptor type-1 | 2.7.11.30 | 0.461 | |
| 2xrw | ANP | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.460 | |
| 3b8q | 900 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.460 | |
| 3v5j | 0F2 | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.460 | |
| 4aa5 | NQB | Mitogen-activated protein kinase 14 | / | 0.460 | |
| 4k0y | 1OA | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.460 | |
| 1jvs | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.459 | |
| 1pme | SB2 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.459 | |
| 1pmn | 984 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.459 | |
| 2pwl | ACP | Fibroblast growth factor receptor 2 | / | 0.459 | |
| 2wmw | ZYW | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.459 | |
| 2wmx | ZY6 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.459 | |
| 2ym6 | YM6 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.459 | |
| 3igo | ANP | Calmodulin-domain protein kinase 1, putative | / | 0.459 | |
| 3jy0 | LYG | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.459 | |
| 3prf | FP3 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.459 | |
| 3t2y | FAD | Sulfide-quinone reductase | / | 0.459 | |
| 3tz3 | B36 | Acetyl-CoA carboxylase | / | 0.459 | |
| 4ih8 | B43 | Calmodulin-domain protein kinase 1 | / | 0.459 | |
| 4k18 | 1OB | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.459 | |
| 5awm | ANP | Stress-activated protein kinase JNK | 2.7.11.24 | 0.459 | |
| 5d12 | G97 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.459 | |
| 2bal | PQA | Mitogen-activated protein kinase 14 | / | 0.458 | |
| 2csn | CKI | Casein kinase I homolog 1 | 2.7.11.1 | 0.458 | |
| 2wle | COA | Polysialic acid O-acetyltransferase | / | 0.458 | |
| 3k5u | PFQ | Aurora kinase A | 2.7.11.1 | 0.458 | |
| 3s2a | 2NQ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.458 | |
| 3u8w | 09J | Mitogen-activated protein kinase 14 | / | 0.458 | |
| 4jbp | YPH | Aurora kinase A | 2.7.11.1 | 0.458 | |
| 4wsq | KSA | AP2-associated protein kinase 1 | 2.7.11.1 | 0.458 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.457 | |
| 1yvj | 4ST | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.457 | |
| 2rl5 | 2RL | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.457 | |
| 2w1e | L0E | Aurora kinase A | 2.7.11.1 | 0.457 | |
| 3erk | SB4 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.457 | |
| 3qp0 | NI8 | Gag-Pol polyprotein | 3.4.23.16 | 0.457 | |
| 4h3y | SAH | tRNA (guanine-N(1)-)-methyltransferase | / | 0.457 | |
| 4jay | FAD | UDP-N-acetylenolpyruvoylglucosamine reductase | / | 0.457 | |
| 4jbo | WPH | Aurora kinase A | 2.7.11.1 | 0.457 | |
| 4jvf | 17X | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.457 | |
| 2f4b | EHA | Peroxisome proliferator-activated receptor gamma | / | 0.456 | |
| 2izt | 23D | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.456 | |
| 3sgx | 0FW | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.456 | |
| 4fny | I3K | ALK tyrosine kinase receptor | 2.7.10.1 | 0.456 | |
| 4kin | 1M8 | Mitogen-activated protein kinase 14 | / | 0.456 | |
| 4utd | ACP | Aurora kinase A | 2.7.11.1 | 0.456 | |
| 5bvw | 1N1 | Epithelial discoidin domain-containing receptor 1 | 2.7.10.1 | 0.456 | |
| 5c8w | PCG | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.456 | |
| 1bxo | PP7 | Penicillopepsin-1 | 3.4.23.20 | 0.455 | |
| 1ict | T44 | Transthyretin | / | 0.455 | |
| 1yi4 | ADN | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.455 | |
| 1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.455 | |
| 3gfe | P37 | Mitogen-activated protein kinase 14 | / | 0.455 | |
| 3upj | U03 | Gag-Pol polyprotein | / | 0.455 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.455 | |
| 4fsq | HK3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.455 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.455 | |
| 1h1s | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
| 1ol5 | ADP | Aurora kinase A | 2.7.11.1 | 0.454 | |
| 2c3q | GTX | Glutathione S-transferase theta-1 | 2.5.1.18 | 0.454 | |
| 2hy8 | 1ST | Serine/threonine-protein kinase PAK 1 | 2.7.11.1 | 0.454 | |
| 2j7t | 274 | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.454 | |
| 2r0u | M54 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.454 | |
| 2vn0 | TDZ | Cytochrome P450 2C8 | / | 0.454 | |
| 2ycf | YCF | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.454 | |
| 3h0a | D30 | Peroxisome proliferator-activated receptor gamma | / | 0.454 | |
| 3qai | XNN | Ketohexokinase | / | 0.454 | |
| 3tmz | 06X | Cytochrome P450 2B4 | 1.14.14.1 | 0.454 | |
| 4fl1 | ANP | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.454 | |
| 4h4z | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.454 | |
| 4ieb | ANP | Calmodulin-domain protein kinase 1 | / | 0.454 | |
| 5doz | NDP | JamJ | / | 0.454 | |
| 2o0u | C0M | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.453 | |
| 2rio | ADP | Serine/threonine-protein kinase/endoribonuclease IRE1 | 2.7.11.1 | 0.453 | |
| 2w7x | D1A | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.453 | |
| 3i0r | RT3 | Gag-Pol polyprotein | 2.7.7.49 | 0.453 | |
| 3mvm | 39P | Mitogen-activated protein kinase 14 | / | 0.453 | |
| 3pe6 | ZYH | Monoglyceride lipase | / | 0.453 | |
| 4bdb | ODO | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.453 | |
| 4joa | 3DK | ALK tyrosine kinase receptor | 2.7.10.1 | 0.453 | |
| 5jtb | ZMA | Adenosine receptor A2a | / | 0.453 | |
| 4z35 | ON9 | Lysophosphatidic acid receptor 1 | / | 0.453 | |
| 4ug2 | NGI | Adenosine receptor A2a | / | 0.453 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.452 | |
| 1k6t | XN1 | Gag-Pol polyprotein | 3.4.23.16 | 0.452 | |
| 1yt9 | OIS | Gag-Pol polyprotein | / | 0.452 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.452 | |
| 2hw2 | RFP | Rifampin ADP-ribosyl transferase | / | 0.452 | |
| 2q6s | PLB | Peroxisome proliferator-activated receptor gamma | / | 0.452 | |
| 2xyn | VX6 | Abelson tyrosine-protein kinase 2 | 2.7.10.2 | 0.452 | |
| 3b2t | M33 | Fibroblast growth factor receptor 2 | / | 0.452 | |
| 3q3b | 55E | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.452 | |
| 3tqh | NDP | Quinone oxidoreductase | / | 0.452 | |
| 3w1f | 1O5 | Dual specificity protein kinase TTK | 2.7.12.1 | 0.452 | |
| 4b10 | NHW | Glycylpeptide N-tetradecanoyltransferase | / | 0.452 | |
| 4dce | 0JF | ALK tyrosine kinase receptor | 2.7.10.1 | 0.452 | |
| 4g34 | 924 | Eukaryotic translation initiation factor 2-alpha kinase 3 | 2.7.11.1 | 0.452 | |
| 5csh | ATP | Casein kinase II subunit alpha | 2.7.11.1 | 0.452 | |
| 1dkf | BMS | Retinoic acid receptor alpha | / | 0.451 | |
| 1g4t | FTP | Thiamine-phosphate synthase | / | 0.451 | |
| 1jq5 | NAD | Glycerol dehydrogenase | 1.1.1.6 | 0.451 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.451 | |
| 2g2f | AGS | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.451 | |
| 2w0j | ZAT | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.451 | |
| 2ycs | NXP | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.451 | |
| 3cgb | FAD | Coenzyme A disulfide reductase | / | 0.451 | |
| 3f88 | 3HT | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.451 | |
| 4bb5 | HD2 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.451 | |
| 4bcr | WY1 | Peroxisome proliferator-activated receptor alpha | / | 0.451 | |
| 4gvj | ADP | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.451 | |
| 4y95 | 746 | Tyrosine-protein kinase | / | 0.451 | |
| 1ir3 | ANP | Insulin receptor | 2.7.10.1 | 0.450 | |
| 1k6c | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.450 | |
| 1oec | AA2 | Fibroblast growth factor receptor 2 | / | 0.450 | |
| 1ppm | 0P1 | Penicillopepsin-1 | 3.4.23.20 | 0.450 | |
| 1uuo | BRF | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.450 | |
| 2cgw | 3C3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.450 | |
| 2jed | LG8 | Protein kinase C theta type | 2.7.11.13 | 0.450 | |
| 2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.450 | |
| 2w9s | TOP | Dihydrofolate reductase type 1 from Tn4003 | 1.5.1.3 | 0.450 | |
| 3a14 | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.450 | |
| 3gu8 | 3GU | Death-associated protein kinase 1 | 2.7.11.1 | 0.450 | |
| 3icr | COA | Coenzyme A disulfide reductase | / | 0.450 | |
| 3qk0 | QK0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.450 | |
| 3tuc | FPW | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.450 | |
| 4cd0 | AWJ | ALK tyrosine kinase receptor | 2.7.10.1 | 0.450 | |
| 4eh6 | 0ON | Mitogen-activated protein kinase 14 | / | 0.450 | |
| 5dr9 | SKE | Aurora kinase A | 2.7.11.1 | 0.450 | |
| 5uvi | ZMA | Adenosine receptor A2a | / | 0.450 | |
| 1ivq | 0PX | Gag-Pol polyprotein | / | 0.449 | |
| 1k6v | XN2 | Gag-Pol polyprotein | 3.4.23.16 | 0.449 | |
| 2f8g | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.449 | |
| 2v7a | 627 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.449 | |
| 2xru | 400 | Aurora kinase A | 2.7.11.1 | 0.449 | |
| 2xye | CXG | Gag-Pol polyprotein | / | 0.449 | |
| 3bgp | VX1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.449 | |
| 3d7t | STU | Tyrosine-protein kinase CSK | / | 0.449 | |
| 3el4 | ROC | Gag-Pol polyprotein | 3.4.23.16 | 0.449 | |
| 3kpk | FAD | Sulfide-quinone reductase | / | 0.449 | |
| 3ml9 | ML9 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.449 | |
| 4erw | STU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 4fuy | EK2 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.449 | |
| 4hle | 17V | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.449 | |
| 4i0r | 1B4 | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.449 | |
| 4kbc | 1QJ | Casein kinase I isoform delta | 2.7.11.1 | 0.449 | |
| 4nr4 | 2LK | CREB-binding protein | / | 0.449 | |
| 4xgx | ADP | FAD:protein FMN transferase | / | 0.449 | |
| 5eai | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.449 | |
| 5f0a | 1FB | cGMP-dependent protein kinase, putative | / | 0.449 | |
| 1i8t | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.448 | |
| 1osv | CHC | Bile acid receptor | / | 0.448 | |
| 2ayp | 43A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.448 | |
| 2jd0 | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.448 | |
| 2yir | YIR | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.448 | |
| 3fkl | FKL | Mitogen-activated protein kinase 14 | / | 0.448 | |
| 3hwr | NDP | 2-dehydropantoate 2-reductase | / | 0.448 | |
| 3iae | D7K | Benzaldehyde lyase | / | 0.448 | |
| 3iph | G11 | Mitogen-activated protein kinase 14 | / | 0.448 | |
| 3mfu | ANP | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.448 | |
| 3qa2 | XNA | Ketohexokinase | / | 0.448 | |
| 3r9d | X6B | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
| 3zze | 6XP | Hepatocyte growth factor receptor | 2.7.10.1 | 0.448 | |
| 4b7d | QLE | Cytochrome P450 monooxygenase PikC | / | 0.448 | |
| 4dn5 | AGS | Mitogen-activated protein kinase kinase kinase 14 | 2.7.11.25 | 0.448 | |
| 4ftk | H9K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.448 | |
| 4loo | SB4 | Mitogen-activated protein kinase 14 | / | 0.448 | |
| 4n9i | PCG | Catabolite expression activator | / | 0.448 | |
| 4nkv | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.448 | |
| 4xld | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.448 | |
| 5iua | 6DX | Adenosine receptor A2a | / | 0.448 | |
| 1phg | MYT | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 2gek | GDP | Phosphatidyl-myo-inositol mannosyltransferase | 2.4.1.57 | 0.447 | |
| 2gqg | 1N1 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.447 | |
| 2i4j | DRJ | Peroxisome proliferator-activated receptor gamma | / | 0.447 | |
| 2wbd | RO5 | Fructose-1,6-bisphosphatase 1 | 3.1.3.11 | 0.447 | |
| 2yfe | YFE | Peroxisome proliferator-activated receptor gamma | / | 0.447 | |
| 3cuk | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.447 | |
| 3l1s | Z92 | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.447 | |
| 4afj | SJJ | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.447 | |
| 4anq | VGH | ALK tyrosine kinase receptor | 2.7.10.1 | 0.447 | |
| 4c4i | X20 | Dual specificity protein kinase TTK | 2.7.12.1 | 0.447 | |
| 4e4m | 0NH | Tyrosine-protein kinase JAK2 | / | 0.447 | |
| 4ezk | 0SD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.447 | |
| 4okx | 198 | Androgen receptor | / | 0.447 | |
| 4rph | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.447 | |
| 5eow | FAD | 6-hydroxynicotinate 3-monooxygenase | 1.14.13.114 | 0.447 | |
| 1c6y | MK1 | Protease | / | 0.446 | |
| 1pp9 | SMA | Cytochrome b | / | 0.446 | |
| 2etm | 7PY | Focal adhesion kinase 1 | 2.7.10.2 | 0.446 | |
| 2vxo | XMP | GMP synthase [glutamine-hydrolyzing] | 6.3.5.2 | 0.446 | |
| 2y46 | MIV | Mycinamicin IV hydroxylase/epoxidase | / | 0.446 | |
| 2zno | S44 | Peroxisome proliferator-activated receptor gamma | / | 0.446 | |
| 3b2e | ADP | ATPase GET3 | / | 0.446 | |
| 3gbu | ATP | Uncharacterized sugar kinase PH1459 | 2.7.1 | 0.446 | |
| 3i59 | N6R | CRP-like cAMP-activated global transcriptional regulator | / | 0.446 | |
| 3iw4 | LW4 | Protein kinase C alpha type | 2.7.11.13 | 0.446 | |
| 3jxw | LXG | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.446 | |
| 3q5i | ANP | Protein kinase, putative | / | 0.446 | |
| 3qfv | NM7 | Serine/threonine-protein kinase MRCK beta | 2.7.11.1 | 0.446 | |
| 3umx | Q18 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.446 | |
| 3uwq | U5P | Orotidine 5'-phosphate decarboxylase | / | 0.446 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 4bgg | 844 | Activin receptor type-1 | 2.7.11.30 | 0.446 | |
| 4dpw | AGS | Mevalonate diphosphate decarboxylase | / | 0.446 | |
| 4f63 | 0S7 | Fibroblast growth factor receptor 1 | / | 0.446 | |
| 4g17 | 0VN | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.446 | |
| 4hw3 | 19G | Induced myeloid leukemia cell differentiation protein Mcl-1 | / | 0.446 | |
| 4ia2 | BIV | Vitamin D3 receptor A | / | 0.446 | |
| 4mcb | 21W | tRNA (guanine-N(1)-)-methyltransferase | 2.1.1.228 | 0.446 | |
| 4oj4 | DIF | Peroxisome proliferator-activated receptor gamma | / | 0.446 | |
| 4rup | H97 | Vitamin D3 receptor A | / | 0.446 | |
| 4u03 | GTP | Cyclic GMP-AMP synthase | / | 0.446 | |
| 1bsv | NDP | GDP-L-fucose synthase | / | 0.445 | |
| 1gqt | ACP | Ribokinase | / | 0.445 | |
| 1sgu | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 1szm | BI4 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.445 | |
| 1z1r | HBH | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 2g5c | NAD | Prephenate dehydrogenase | / | 0.445 | |
| 2j2i | LY4 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.445 | |
| 2w1f | L0F | Aurora kinase A | 2.7.11.1 | 0.445 | |
| 2yjx | YJX | Heat shock protein HSP 90-alpha | / | 0.445 | |
| 3hdm | MMG | Serine/threonine-protein kinase Sgk1 | 2.7.11.1 | 0.445 | |
| 3lu8 | IQX | Serum albumin | / | 0.445 | |
| 3r6s | CMP | CRP-like cAMP-activated global transcriptional regulator | / | 0.445 | |
| 3rep | ATP | Integrin-linked protein kinase | 2.7.11.1 | 0.445 | |
| 3sdi | 3SD | Proteasome subunit beta type-5 | 3.4.25.1 | 0.445 | |
| 3sdi | 3SD | Proteasome subunit beta type-6 | 3.4.25.1 | 0.445 | |
| 3sdk | P3N | Proteasome subunit beta type-5 | 3.4.25.1 | 0.445 | |
| 3sdk | P3N | Proteasome subunit beta type-6 | 3.4.25.1 | 0.445 | |
| 3ump | ATP | ATP-dependent 6-phosphofructokinase isozyme 2 | 2.7.1.11 | 0.445 | |
| 4b7s | QLE | Cytochrome P450 monooxygenase PikC | / | 0.445 | |
| 4ejn | 0R4 | RAC-alpha serine/threonine-protein kinase | 2.7.11.1 | 0.445 | |
| 4jbq | VX6 | Aurora kinase A | 2.7.11.1 | 0.445 | |
| 4mxa | BK7 | Calmodulin-like domain protein kinase isoenzyme gamma, related | / | 0.445 | |
| 4zs2 | FLU | Alpha-ketoglutarate-dependent dioxygenase FTO | / | 0.445 | |
| 1a5u | ATP | Pyruvate kinase PKM | 2.7.1.40 | 0.444 | |
| 1aj8 | COA | Citrate synthase | / | 0.444 | |
| 1cde | GAR | Phosphoribosylglycinamide formyltransferase | / | 0.444 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.444 | |
| 1i7i | AZ2 | Peroxisome proliferator-activated receptor gamma | / | 0.444 | |
| 1nvq | UCN | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
| 1u59 | STU | Tyrosine-protein kinase ZAP-70 | 2.7.10.2 | 0.444 | |
| 1yi3 | LY2 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.444 | |
| 2b7z | MK1 | Gag-Pol polyprotein | / | 0.444 | |
| 2bx8 | AZQ | Serum albumin | / | 0.444 | |
| 2gtk | 208 | Peroxisome proliferator-activated receptor gamma | / | 0.444 | |
| 2j0j | 4ST | Focal adhesion kinase 1 | 2.7.10.2 | 0.444 | |
| 2jds | L20 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.444 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.444 | |
| 2wdz | NAD | Galactitol dehydrogenase | / | 0.444 | |
| 2y05 | NAP | Prostaglandin reductase 1 | / | 0.444 | |
| 2yxu | ATP | Pyridoxal kinase | 2.7.1.35 | 0.444 | |
| 3ggo | NAI | Prephenate dehydrogenase | / | 0.444 | |
| 4aac | AAV | Mitogen-activated protein kinase 14 | / | 0.444 | |
| 4c34 | STU | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.444 | |
| 4dk5 | 0KO | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.444 | |
| 4f9m | FCM | Peroxisome proliferator-activated receptor gamma | / | 0.444 | |
| 4hee | 14R | Peroxisome proliferator-activated receptor gamma | / | 0.444 | |
| 4jib | 1L6 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.444 | |
| 4mbl | 26L | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.444 | |
| 1c1d | NAI | Phenylalanine dehydrogenase | / | 0.443 | |
| 1jld | 0PP | Gag-Pol polyprotein | / | 0.443 | |
| 1qxl | FR8 | Adenosine deaminase | 3.5.4.4 | 0.443 | |
| 1tqm | ANP | RIO-type serine/threonine-protein kinase Rio2 | 2.7.11.1 | 0.443 | |
| 1xjd | STU | Protein kinase C theta type | 2.7.11.13 | 0.443 | |
| 1yb5 | NAP | Quinone oxidoreductase | 1.6.5.5 | 0.443 | |
| 2ath | 3EA | Peroxisome proliferator-activated receptor gamma | / | 0.443 | |
| 2c59 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.443 | |
| 2cke | IQU | Death-associated protein kinase 2 | / | 0.443 | |
| 2j0k | 4ST | Focal adhesion kinase 1 | 2.7.10.2 | 0.443 | |
| 2q61 | SF1 | Peroxisome proliferator-activated receptor gamma | / | 0.443 | |
| 2qd8 | 065 | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 2wec | PP5 | Penicillopepsin-1 | 3.4.23.20 | 0.443 | |
| 2yaa | ATP | Death-associated protein kinase 2 | / | 0.443 | |
| 3cgf | JNF | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.443 | |
| 3crl | ANP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial | 2.7.11.2 | 0.443 | |
| 3em6 | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 3iw8 | HIZ | Mitogen-activated protein kinase 14 | / | 0.443 | |
| 3llt | ANP | Protein serine/threonine kinase-1 | / | 0.443 | |
| 3mvl | 38P | Mitogen-activated protein kinase 14 | / | 0.443 | |
| 3ruk | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.443 | |
| 3wmx | NAD | NAD dependent epimerase/dehydratase | / | 0.443 | |
| 4ezl | 0SE | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.443 | |
| 4g31 | 0WH | Eukaryotic translation initiation factor 2-alpha kinase 3 | 2.7.11.1 | 0.443 | |
| 4nj3 | 2KD | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.443 | |
| 4v12 | POG | MaoC like domain protein | / | 0.443 | |
| 4zoh | FAD | Putative oxidoreductase FAD-binding subunit | / | 0.443 | |
| 5dc5 | B3N | Histone deacetylase 8 | 3.5.1.98 | 0.443 | |
| 1cm8 | ANP | Mitogen-activated protein kinase 12 | / | 0.442 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.442 | |
| 1v59 | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.442 | |
| 1wuu | ANP | Galactokinase | 2.7.1.6 | 0.442 | |
| 2e9u | A25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
| 2hfp | NSI | Peroxisome proliferator-activated receptor gamma | / | 0.442 | |
| 2i4p | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.442 | |
| 2izs | BRQ | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.442 | |
| 2nru | T12 | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.442 | |
| 2o2u | 738 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.442 | |
| 2oye | IM8 | Prostaglandin G/H synthase 1 | 1.14.99.1 | 0.442 | |
| 2qfx | NDP | Isocitrate dehydrogenase [NADP], mitochondrial | 1.1.1.42 | 0.442 | |
| 2qo6 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.442 | |
| 2x7f | 824 | TRAF2 and NCK-interacting protein kinase | 2.7.11.1 | 0.442 | |
| 2xf0 | 4UB | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
| 2xik | J60 | Serine/threonine-protein kinase 25 | 2.7.11.1 | 0.442 | |
| 2znn | S44 | Peroxisome proliferator-activated receptor alpha | / | 0.442 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.442 | |
| 3apf | BMW | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.442 | |
| 3ds6 | A17 | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 3flk | NAI | Tartrate dehydrogenase/decarboxylase | 1.1.1.93 | 0.442 | |
| 3fls | FLS | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 3ijd | C2F | Methylenetetrahydrofolate reductase | / | 0.442 | |
| 3mwu | BK3 | Calmodulin-domain protein kinase 1, putative | / | 0.442 | |
| 3vcy | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.442 | |
| 3vso | EK1 | Peroxisome proliferator-activated receptor gamma | / | 0.442 | |
| 3zpt | M8Y | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 3zpu | M8B | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.442 | |
| 4cta | ATP | CinA-like protein | / | 0.442 | |
| 4e4q | RRH | Peroxisome proliferator-activated receptor gamma | / | 0.442 | |
| 4fhi | 0S4 | Vitamin D3 receptor A | / | 0.442 | |
| 4ftj | H8K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
| 4hur | ACO | Virginiamycin A acetyltransferase | 2.3.1 | 0.442 | |
| 4j5j | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 4kba | 1QM | Casein kinase I isoform delta | 2.7.11.1 | 0.442 | |
| 4l2i | FAD | Electron transfer flavoprotein alpha/beta-subunit | / | 0.442 | |
| 4l7f | 1V5 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.442 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.442 | |
| 4rpg | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.442 | |
| 4zzj | CNA | NAD-dependent protein deacetylase sirtuin-1 | 3.5.1 | 0.442 | |
| 5ify | UMP | Glucose-1-phosphate thymidylyltransferase | / | 0.442 | |
| 1dss | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.441 | |
| 1jsc | FAD | Acetolactate synthase catalytic subunit, mitochondrial | 2.2.1.6 | 0.441 | |
| 1oky | STU | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.441 | |
| 1okz | UCN | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.441 | |
| 1ppj | SMA | Cytochrome b | / | 0.441 | |
| 1rek | B8L | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.441 | |
| 1v9a | SAH | Uncharacterized protein | / | 0.441 | |
| 1xl2 | 189 | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 2b1p | AIZ | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.441 | |
| 2bb9 | AKC | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 2chz | 093 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.441 | |
| 2pr2 | DG1 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 3fco | IIG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.441 | |
| 3int | FDA | UDP-galactopyranose mutase | 5.4.99.9 | 0.441 | |
| 3nbw | TR4 | Ketohexokinase | / | 0.441 | |
| 3ndu | ROC | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 3opd | HIE | Heat shock protein 83 | / | 0.441 | |
| 4c3p | ACP | Aurora kinase A | 2.7.11.1 | 0.441 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.441 | |
| 4i0s | 1B5 | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.441 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.441 | |
| 4jk4 | DIU | Serum albumin | / | 0.441 | |
| 5aac | VGH | ALK tyrosine kinase receptor | 2.7.10.1 | 0.441 | |
| 3rey | XAC | Adenosine receptor A2a | / | 0.441 | |
| 1n4h | REA | Nuclear receptor ROR-beta | / | 0.440 | |
| 1wvg | APR | CDP-glucose 4,6-dehydratase | 4.2.1.45 | 0.440 | |
| 1ywr | LI9 | Mitogen-activated protein kinase 14 | / | 0.440 | |
| 1zhw | HC2 | Oxysterol-binding protein homolog 4 | / | 0.440 | |
| 1zmc | NAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.440 | |
| 2i4z | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.440 | |
| 2jko | BIJ | Focal adhesion kinase 1 | 2.7.10.2 | 0.440 | |
| 2ym7 | YM7 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 3be2 | RAJ | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.440 | |
| 3cqe | P91 | Wee1-like protein kinase | 2.7.10.2 | 0.440 | |
| 3fzp | AGS | Protein-tyrosine kinase 2-beta | 2.7.10.2 | 0.440 | |
| 3juh | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.440 | |
| 3lin | E13 | Protease | / | 0.440 | |
| 3mee | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.440 | |
| 3nbv | ANP | Ketohexokinase | / | 0.440 | |
| 3oev | 3OE | Proteasome subunit beta type-5 | 3.4.25.1 | 0.440 | |
| 3oev | 3OE | Proteasome subunit beta type-6 | 3.4.25.1 | 0.440 | |
| 3oew | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 3uyt | 0CK | Casein kinase I isoform delta | 2.7.11.1 | 0.440 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.440 | |
| 4a6c | QG9 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 4bcq | TJF | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 4ele | 31I | Dihydrofolate reductase | / | 0.440 | |
| 4ftl | H0K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 4g16 | 0VM | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.440 | |
| 4grb | 0XG | Casein kinase II subunit alpha | 2.7.11.1 | 0.440 | |
| 4in4 | 4ID | Kelch-like ECH-associated protein 1 | / | 0.440 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.440 | |
| 4oa9 | ANP | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.440 | |
| 4qmn | DB8 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.440 | |
| 4xum | IMN | Peroxisome proliferator-activated receptor gamma | / | 0.440 | |
| 5auw | QUE | Death-associated protein kinase 1 | 2.7.11.1 | 0.440 | |
| 5k2d | ZMA | Adenosine receptor A2a | / | 0.440 | |
| 4z34 | ON7 | Lysophosphatidic acid receptor 1 | / | 0.440 |