Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3hko | ANP | Calcium/calmodulin-dependent protein kinase with a kinase domain and 2 calmodulin-like EF hands |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3hko | ANP | Calcium/calmodulin-dependent protein kinase with a kinase domain and 2 calmodulin-like EF hands | / | 1.000 | |
| 2hen | ADP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.560 | |
| 3c4w | ATP | Rhodopsin kinase | / | 0.545 | |
| 2qoq | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.538 | |
| 1q97 | ATP | Serine/threonine-protein kinase SKY1 | 2.7.11.1 | 0.531 | |
| 3c4z | ADP | Rhodopsin kinase | / | 0.527 | |
| 2wqe | ADP | Aurora kinase A | 2.7.11.1 | 0.525 | |
| 3qc9 | ADP | Rhodopsin kinase | / | 0.525 | |
| 4l9i | 8PR | Rhodopsin kinase | / | 0.525 | |
| 2ijm | ATP | Focal adhesion kinase 1 | 2.7.10.2 | 0.524 | |
| 2qo7 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.521 | |
| 4c3p | ACP | Aurora kinase A | 2.7.11.1 | 0.516 | |
| 4qny | ANP | Mitogen activated protein kinase, putative | / | 0.516 | |
| 4dee | ADP | Aurora kinase A | 2.7.11.1 | 0.515 | |
| 5l8l | ADP | Aurora kinase A | 2.7.11.1 | 0.514 | |
| 4fl2 | ANP | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.509 | |
| 3t8o | ATP | Rhodopsin kinase | / | 0.508 | |
| 1ny3 | ADP | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.507 | |
| 4iaz | ADP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.505 | |
| 3c4x | ATP | Rhodopsin kinase | / | 0.504 | |
| 3fzp | AGS | Protein-tyrosine kinase 2-beta | 2.7.10.2 | 0.504 | |
| 4fl3 | ANP | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.502 | |
| 4pl4 | ADP | Serine/threonine-protein kinase/endoribonuclease IRE1 | 2.7.11.1 | 0.502 | |
| 2v7a | 627 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.501 | |
| 4fv3 | EK6 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.501 | |
| 2j0m | 4ST | Focal adhesion kinase 1 | 2.7.10.2 | 0.499 | |
| 1u54 | ACP | Activated CDC42 kinase 1 | / | 0.498 | |
| 4yhj | AN2 | G protein-coupled receptor kinase 4 | 2.7.11.16 | 0.498 | |
| 4btj | ADP | Tau-tubulin kinase 1 | 2.7.11.1 | 0.497 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.495 | |
| 3p23 | ADP | Serine/threonine-protein kinase/endoribonuclease IRE1 | 2.7.11.1 | 0.495 | |
| 4qml | ANP | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.495 | |
| 2j0l | ANP | Focal adhesion kinase 1 | 2.7.10.2 | 0.493 | |
| 4awi | AQ2 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.493 | |
| 5dos | ATP | Aurora kinase A | 2.7.11.1 | 0.493 | |
| 2fsv | NAD | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.491 | |
| 5dnr | ATP | Aurora kinase A | 2.7.11.1 | 0.491 | |
| 4j95 | ACP | Fibroblast growth factor receptor 2 | / | 0.490 | |
| 1j1c | ADP | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.489 | |
| 3i5z | Z48 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.488 | |
| 2phk | ATP | Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform | 2.7.11.19 | 0.487 | |
| 2yxu | ATP | Pyridoxal kinase | 2.7.1.35 | 0.487 | |
| 3gu7 | ADP | Death-associated protein kinase 1 | 2.7.11.1 | 0.487 | |
| 5dt3 | ATP | Aurora kinase A | 2.7.11.1 | 0.487 | |
| 1i44 | ACP | Insulin receptor | 2.7.10.1 | 0.486 | |
| 2py3 | ACP | Fibroblast growth factor receptor 2 | / | 0.486 | |
| 1q8y | ADP | Serine/threonine-protein kinase SKY1 | 2.7.11.1 | 0.485 | |
| 3a7h | ATP | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.485 | |
| 3i60 | E86 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.485 | |
| 4k33 | ACP | Fibroblast growth factor receptor 3 | 2.7.10.1 | 0.485 | |
| 1ir3 | ANP | Insulin receptor | 2.7.10.1 | 0.484 | |
| 3nsz | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.484 | |
| 4qpm | ADP | Mitotic checkpoint serine/threonine-protein kinase BUB1 | 2.7.11.1 | 0.484 | |
| 4gu9 | 4GU | Focal adhesion kinase 1 | 2.7.10.2 | 0.483 | |
| 4xw5 | ATP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.483 | |
| 3lu7 | IPX | Serum albumin | / | 0.482 | |
| 4lrj | ANP | Uncharacterized protein | / | 0.482 | |
| 1qpj | STU | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.481 | |
| 2w1f | L0F | Aurora kinase A | 2.7.11.1 | 0.481 | |
| 4fv5 | EK9 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.481 | |
| 4j99 | ACP | Fibroblast growth factor receptor 2 | / | 0.481 | |
| 4oa9 | ANP | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.481 | |
| 1pdh | FAS | p-hydroxybenzoate hydroxylase | / | 0.479 | |
| 4ii5 | ADP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.479 | |
| 4jrn | ANP | Rhoptry kinase family protein | / | 0.479 | |
| 4o0u | ADN | Aurora kinase A | 2.7.11.1 | 0.479 | |
| 3ori | AGS | Serine/threonine protein kinase | / | 0.478 | |
| 4iay | ADP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.478 | |
| 1zth | ADP | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.477 | |
| 2rio | ADP | Serine/threonine-protein kinase/endoribonuclease IRE1 | 2.7.11.1 | 0.477 | |
| 4gk3 | L87 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.477 | |
| 1u5r | ATP | Serine/threonine-protein kinase TAO2 | 2.7.11.1 | 0.476 | |
| 1xr1 | ANP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.476 | |
| 3c50 | ADP | Rhodopsin kinase | / | 0.476 | |
| 4ftt | 6HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.476 | |
| 4iak | ADP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.476 | |
| 4eoo | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.475 | |
| 4fvq | ATP | Tyrosine-protein kinase JAK2 | / | 0.475 | |
| 3c0i | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.473 | |
| 4btj | ATP | Tau-tubulin kinase 1 | 2.7.11.1 | 0.473 | |
| 5dn3 | ATP | Aurora kinase A | 2.7.11.1 | 0.473 | |
| 2qoc | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.472 | |
| 3cok | ANP | Serine/threonine-protein kinase PLK4 | 2.7.11.21 | 0.472 | |
| 4ekk | ANP | RAC-alpha serine/threonine-protein kinase | 2.7.11.1 | 0.472 | |
| 1t0l | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.471 | |
| 1zp9 | ATP | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.471 | |
| 3i4b | Z48 | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.471 | |
| 2ozo | ANP | Tyrosine-protein kinase ZAP-70 | 2.7.10.2 | 0.469 | |
| 2pdt | FAD | Vivid PAS protein VVD | / | 0.469 | |
| 4aw0 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.469 | |
| 4mvf | STU | Calcium-dependent protein kinase 2 | 2.7.11.1 | 0.469 | |
| 4nmd | FDA | Bifunctional protein PutA | / | 0.469 | |
| 4xlv | ACP | Insulin receptor | 2.7.10.1 | 0.469 | |
| 1jqh | ANP | Insulin-like growth factor 1 receptor | 2.7.10.1 | 0.468 | |
| 2lba | CHO | Fatty acid binding protein 6 | / | 0.468 | |
| 3lj3 | WYE | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.468 | |
| 4dh5 | ADP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.468 | |
| 4fg8 | ATP | Calcium/calmodulin-dependent protein kinase type 1 | 2.7.11.17 | 0.468 | |
| 5i4n | ATP | Tyrosine-protein kinase JAK2 | / | 0.468 | |
| 2cjm | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.467 | |
| 4ysj | ADP | Calmodulin-like domain protein kinase | / | 0.467 | |
| 5cnn | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.467 | |
| 1ol7 | ADP | Aurora kinase A | 2.7.11.1 | 0.466 | |
| 1u28 | NAD | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.466 | |
| 2a19 | ANP | Interferon-induced, double-stranded RNA-activated protein kinase | 2.7.11.1 | 0.466 | |
| 4jia | 1K3 | Tyrosine-protein kinase JAK2 | / | 0.466 | |
| 4l3l | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.466 | |
| 4z34 | ON7 | Lysophosphatidic acid receptor 1 | / | 0.466 | |
| 3tdw | GDP | Gentamicin resistance protein | / | 0.465 | |
| 4yzc | STU | Serine/threonine-protein kinase/endoribonuclease IRE1 | 2.7.11.1 | 0.465 | |
| 5c03 | AGS | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.465 | |
| 1l8q | ADP | Chromosomal replication initiator protein DnaA | / | 0.464 | |
| 2fj1 | CTC | Tetracycline repressor protein class D | / | 0.464 | |
| 2xuu | ADP | Death-associated protein kinase 1 | 2.7.11.1 | 0.464 | |
| 2y3s | TIR | TamL | / | 0.464 | |
| 3cd5 | 7HI | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.34 | 0.464 | |
| 3ge1 | ADP | Glycerol kinase | / | 0.464 | |
| 3tdv | GDP | Gentamicin resistance protein | / | 0.464 | |
| 4hbm | 0Y7 | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.464 | |
| 2b9i | ADP | Mitogen-activated protein kinase FUS3 | 2.7.11.24 | 0.463 | |
| 2gu8 | 796 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.463 | |
| 2p33 | J07 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.463 | |
| 2xs0 | ANP | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.463 | |
| 2y3r | TRK | TamL | / | 0.463 | |
| 3hrf | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.463 | |
| 4b8l | A0P | Aurora kinase B-A | 2.7.11.1 | 0.463 | |
| 4bii | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.463 | |
| 4cd0 | AWJ | ALK tyrosine kinase receptor | 2.7.10.1 | 0.463 | |
| 1ci0 | FMN | Pyridoxamine 5'-phosphate oxidase | 1.4.3.5 | 0.462 | |
| 1mqb | ANP | Ephrin type-A receptor 2 | 2.7.10.1 | 0.462 | |
| 2bmc | MPY | Aurora kinase A | 2.7.11.1 | 0.462 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.462 | |
| 2ojj | 82A | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.462 | |
| 3pe2 | E1B | Casein kinase II subunit alpha | 2.7.11.1 | 0.462 | |
| 4fhj | 0TZ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.462 | |
| 1byg | STU | Tyrosine-protein kinase CSK | / | 0.461 | |
| 2bxo | OPB | Serum albumin | / | 0.461 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.461 | |
| 3qcs | 3Q1 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.461 | |
| 4wbb | ADP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.461 | |
| 3lpb | NVB | Tyrosine-protein kinase JAK2 | / | 0.460 | |
| 3qd0 | 3Q4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.460 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.460 | |
| 4ct2 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.460 | |
| 4fg9 | ATP | Calcium/calmodulin-dependent protein kinase type 1 | 2.7.11.17 | 0.460 | |
| 4h9t | HL4 | Phosphotriesterase | / | 0.460 | |
| 1jnk | ANP | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.459 | |
| 2uzw | SS4 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.459 | |
| 3kvx | FMY | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.459 | |
| 3ml8 | ML8 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.459 | |
| 3niz | ADP | Cdc2-like CDK2/CDC28 like protein kinase | / | 0.459 | |
| 4fg7 | ATP | Calcium/calmodulin-dependent protein kinase type 1 | 2.7.11.17 | 0.459 | |
| 4fsn | A58 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.459 | |
| 4rqk | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.459 | |
| 1e90 | MYC | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.458 | |
| 1gzu | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.458 | |
| 1rkx | NAD | CDP-D-glucose-4,6-dehydratase | / | 0.458 | |
| 2b9f | ADP | Mitogen-activated protein kinase FUS3 | 2.7.11.24 | 0.458 | |
| 2j4z | 626 | Aurora kinase A | 2.7.11.1 | 0.458 | |
| 2vwu | 7X1 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.458 | |
| 2z7q | ACP | Ribosomal protein S6 kinase alpha-1 | 2.7.11.1 | 0.458 | |
| 3cly | ACP | Fibroblast growth factor receptor 2 | / | 0.458 | |
| 3k5u | PFQ | Aurora kinase A | 2.7.11.1 | 0.458 | |
| 3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.458 | |
| 4lfi | GNP | Casein kinase II subunit alpha | 2.7.11.1 | 0.458 | |
| 4o1p | ANP | Ribonuclease L | / | 0.458 | |
| 4q5j | ANP | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.458 | |
| 5eg3 | ACP | Fibroblast growth factor receptor 2 | / | 0.458 | |
| 5l8j | ADP | Aurora kinase A | 2.7.11.1 | 0.458 | |
| 2qo5 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.457 | |
| 3g8d | ADP | Biotin carboxylase | 6.3.4.14 | 0.457 | |
| 3ork | AGS | Serine/threonine protein kinase | / | 0.457 | |
| 3rep | ATP | Integrin-linked protein kinase | 2.7.11.1 | 0.457 | |
| 3w0s | ANP | Hygromycin-B 4-O-kinase | 2.7.1.163 | 0.457 | |
| 4fsw | HK6 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.457 | |
| 4ly9 | 1YY | Glucokinase regulatory protein | / | 0.457 | |
| 4zse | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.457 | |
| 1ig1 | ANP | Death-associated protein kinase 1 | 2.7.11.1 | 0.456 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.456 | |
| 2biy | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.456 | |
| 2chx | 090 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.456 | |
| 2hy0 | 306 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.456 | |
| 2oor | NAD | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.456 | |
| 2w4j | ADP | Death-associated protein kinase 1 | 2.7.11.1 | 0.456 | |
| 4bbe | 3O4 | Tyrosine-protein kinase JAK2 | / | 0.456 | |
| 4e5y | NDP | GDP-L-fucose synthase | 1.1.1.271 | 0.456 | |
| 5cvh | ADP | Casein kinase II subunit alpha | 2.7.11.1 | 0.456 | |
| 5e92 | ANP | TGF-beta receptor type-2 | 2.7.11.30 | 0.456 | |
| 1fm7 | DFV | Chalcone--flavonone isomerase 1 | 5.5.1.6 | 0.455 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 1qmz | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.455 | |
| 2acx | ANP | G protein-coupled receptor kinase 6 | 2.7.11.16 | 0.455 | |
| 2pui | ADP | Methylthioribose kinase | 2.7.1.100 | 0.455 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.455 | |
| 3my5 | RFZ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.455 | |
| 4fv6 | E57 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.455 | |
| 4iac | ACP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.455 | |
| 4r8q | ADP | Mitotic checkpoint serine/threonine-protein kinase BUB1 | 2.7.11.1 | 0.455 | |
| 4rqv | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.455 | |
| 5iqi | GNP | Bifunctional AAC/APH | 2.3.1 | 0.455 | |
| 1kqu | BR4 | Phospholipase A2, membrane associated | / | 0.454 | |
| 3qcy | 3Q3 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.454 | |
| 3w16 | P9J | Aurora kinase A | 2.7.11.1 | 0.454 | |
| 4b8z | GDP | GDP-L-fucose synthase | 1.1.1.271 | 0.454 | |
| 4bbf | O19 | Tyrosine-protein kinase JAK2 | / | 0.454 | |
| 4ijp | 1EH | Serine/threonine-protein kinase PRP4 homolog | 2.7.11.1 | 0.454 | |
| 1h1w | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.453 | |
| 1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.453 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.453 | |
| 3a8w | ATP | Protein kinase C iota type | 2.7.11.13 | 0.453 | |
| 3jun | AJD | Phenazine biosynthesis protein A/B | / | 0.453 | |
| 3ras | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.453 | |
| 4f6w | 0SS | Cyclin-dependent kinase 8 | 2.7.11.22 | 0.453 | |
| 4fv2 | EK5 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.453 | |
| 4g2f | C07 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.453 | |
| 4gvj | ADP | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.453 | |
| 4ix5 | ANP | Uncharacterized protein | / | 0.453 | |
| 5drd | ATP | Aurora kinase A | 2.7.11.1 | 0.453 | |
| 1cm8 | ANP | Mitogen-activated protein kinase 12 | / | 0.452 | |
| 1hdr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.452 | |
| 1j39 | UPG | DNA beta-glucosyltransferase | / | 0.452 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.452 | |
| 2izs | BRQ | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.452 | |
| 3c0g | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.452 | |
| 3vx4 | ATP | Putative ABC transporter, ATP-binding protein ComA | / | 0.452 | |
| 4fl1 | ANP | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.452 | |
| 1e8z | STU | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.451 | |
| 1j1b | ANP | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.451 | |
| 1j7k | ATP | Holliday junction ATP-dependent DNA helicase RuvB | / | 0.451 | |
| 2chw | 039 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.451 | |
| 2oj9 | BMI | Insulin-like growth factor 1 receptor | 2.7.10.1 | 0.451 | |
| 2ym6 | YM6 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.451 | |
| 3vid | 4TT | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.451 | |
| 4fhk | 0U0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.451 | |
| 4i3z | ADP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
| 4mv4 | ACP | Biotin carboxylase | 6.3.4.14 | 0.451 | |
| 5aaa | VGH | ALK tyrosine kinase receptor | 2.7.10.1 | 0.451 | |
| 5e8y | STU | TGF-beta receptor type-2 | 2.7.11.30 | 0.451 | |
| 1jkk | ANP | Death-associated protein kinase 1 | 2.7.11.1 | 0.450 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.450 | |
| 2q6b | HR2 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.34 | 0.450 | |
| 2w98 | P1Z | Prostaglandin reductase 2 | 1.3.1.48 | 0.450 | |
| 3cvu | FAD | RE11660p | / | 0.450 | |
| 3elb | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.450 | |
| 3ncz | 3NC | Rho-associated protein kinase 1 | 2.7.11.1 | 0.450 | |
| 3orp | AGS | Serine/threonine protein kinase | / | 0.450 | |
| 3u9e | COA | Lmo1369 protein | / | 0.450 | |
| 3zhr | TPP | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.450 | |
| 4bl1 | ANP | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.450 | |
| 4dpm | COA | Malonyl-CoA reductase | 1.2.1.75 | 0.450 | |
| 4fob | 0US | ALK tyrosine kinase receptor | 2.7.10.1 | 0.450 | |
| 4ifc | ADP | Serine/threonine-protein kinase PRP4 homolog | 2.7.11.1 | 0.450 | |
| 4otp | ADP | Serine/threonine-protein kinase RIO1 | 2.7.11.1 | 0.450 | |
| 4rf2 | NAP | NADPH dependent R-specific alcohol dehydrogenase | / | 0.450 | |
| 4s33 | ANP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.450 | |
| 4z69 | DIF | Serum albumin | / | 0.450 | |
| 1ha3 | MAU | Elongation factor Tu-A | / | 0.449 | |
| 1o6y | ACP | Serine/threonine-protein kinase PknB | 2.7.11.1 | 0.449 | |
| 1ol5 | ADP | Aurora kinase A | 2.7.11.1 | 0.449 | |
| 1qxo | FMN | Chorismate synthase | / | 0.449 | |
| 2jn3 | JN3 | Fatty acid-binding protein, liver | / | 0.449 | |
| 2ojg | 19A | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.449 | |
| 2xrw | ANP | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.449 | |
| 3elj | GS7 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.449 | |
| 3tqh | NDP | Quinone oxidoreductase | / | 0.449 | |
| 3ump | ATP | ATP-dependent 6-phosphofructokinase isozyme 2 | 2.7.1.11 | 0.449 | |
| 4bew | CZA | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.449 | |
| 4eak | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.449 | |
| 4en4 | ATP | Pyridoxal kinase | 2.7.1.35 | 0.449 | |
| 4iwo | 1H4 | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.449 | |
| 4jqe | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.449 | |
| 4xx9 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.449 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.448 | |
| 2bfy | H1N | Aurora kinase B-A | 2.7.11.1 | 0.448 | |
| 3a14 | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.448 | |
| 3juq | AJD | Phenazine biosynthesis protein A/B | / | 0.448 | |
| 3lu6 | IMX | Serum albumin | / | 0.448 | |
| 3m31 | FAD | Endoplasmic oxidoreductin-1 | 1.8.4 | 0.448 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.448 | |
| 3qcq | 3Q0 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.448 | |
| 3qd4 | 3Q6 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.448 | |
| 3w2u | ROU | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.448 | |
| 4bge | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.448 | |
| 4bgi | I4I | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.448 | |
| 4bkz | 1WS | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.448 | |
| 4ezk | 0SD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.448 | |
| 4i6g | FAD | Cryptochrome-2 | / | 0.448 | |
| 4iir | ANP | Serine/threonine-protein kinase PRP4 homolog | 2.7.11.1 | 0.448 | |
| 4oau | ADP | 2-5A-dependent ribonuclease | 3.1.26 | 0.448 | |
| 4xcv | NDP | Probable hydroxyacid dehydrogenase protein | / | 0.448 | |
| 1tvo | FRZ | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.447 | |
| 2brb | PFQ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.447 | |
| 2gnh | H52 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.447 | |
| 2j50 | 627 | Aurora kinase A | 2.7.11.1 | 0.447 | |
| 2rds | 1PL | 1-deoxypentalenic acid 11-beta-hydroxylase | 1.14.11.35 | 0.447 | |
| 3e39 | FMN | Nitroreductase | / | 0.447 | |
| 3keu | ATP | Pyridoxal kinase | 2.7.1.35 | 0.447 | |
| 3tm5 | SFG | Uncharacterized protein | / | 0.447 | |
| 3ztx | ZTX | Aurora kinase B-A | 2.7.11.1 | 0.447 | |
| 4aw1 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.447 | |
| 4g1w | G1W | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.447 | |
| 4ivo | ACJ | Protoporphyrinogen oxidase | 1.3.3.4 | 0.447 | |
| 4kcf | AKM | FAD-dependent oxidoreductase | / | 0.447 | |
| 4oti | MI1 | Serine/threonine-protein kinase N1 | / | 0.447 | |
| 1dxo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.446 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.446 | |
| 2aa3 | AP0 | L-lactate dehydrogenase | / | 0.446 | |
| 2b9j | ADP | Mitogen-activated protein kinase FUS3 | 2.7.11.24 | 0.446 | |
| 2hxl | 422 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.446 | |
| 2ic5 | GDP | Ras-related C3 botulinum toxin substrate 3 | / | 0.446 | |
| 2rc3 | NAD | CBS domain | / | 0.446 | |
| 2w4k | ADP | Death-associated protein kinase 1 | 2.7.11.1 | 0.446 | |
| 2wb2 | FAD | RE11660p | / | 0.446 | |
| 2xne | ASH | Aurora kinase A | 2.7.11.1 | 0.446 | |
| 3we4 | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.446 | |
| 4azw | ATP | O-antigen chain terminator bifunctional methyltransferase/kinase WbdD | / | 0.446 | |
| 4bcm | T7Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 4cy8 | FDA | 2-hydroxybiphenyl-3-monooxygenase | / | 0.446 | |
| 4ivg | ANP | TNF receptor-associated protein 1 | / | 0.446 | |
| 5dr2 | ATP | Aurora kinase A | 2.7.11.1 | 0.446 | |
| 1g4t | FTP | Thiamine-phosphate synthase | / | 0.445 | |
| 1g67 | TZP | Thiamine-phosphate synthase | / | 0.445 | |
| 1guf | NDP | Enoyl-[acyl-carrier-protein] reductase 1, mitochondrial | 1.3.1.10 | 0.445 | |
| 2c6d | ANP | Aurora kinase A | 2.7.11.1 | 0.445 | |
| 2ft9 | CHD | Fatty acid-binding protein 2, liver | / | 0.445 | |
| 2vpr | TDC | Tetracycline repressor protein class H | / | 0.445 | |
| 2wmw | ZYW | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.445 | |
| 2wtc | VGM | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.445 | |
| 2xch | CKG | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.445 | |
| 3eej | 53R | Uncharacterized protein | / | 0.445 | |
| 3g51 | ANP | Ribosomal protein S6 kinase alpha-3 | 2.7.11.1 | 0.445 | |
| 3say | OFT | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.445 | |
| 3spt | UD1 | Bifunctional protein GlmU | / | 0.445 | |
| 3zlm | ANP | Adenosine monophosphate-protein transferase NmFic | 2.7.7.n1 | 0.445 | |
| 4ekl | 0RF | RAC-alpha serine/threonine-protein kinase | 2.7.11.1 | 0.445 | |
| 4l45 | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.445 | |
| 1yvj | 4ST | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.444 | |
| 2hog | 710 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
| 2uzt | SS3 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.444 | |
| 2vn9 | GVD | Calcium/calmodulin-dependent protein kinase type II subunit delta | 2.7.11.17 | 0.444 | |
| 3nks | ACJ | Protoporphyrinogen oxidase | 1.3.3.4 | 0.444 | |
| 3p8z | SAH | Genome polyprotein | 2.1.1.56 | 0.444 | |
| 3pxk | PXK | Focal adhesion kinase 1 | 2.7.10.2 | 0.444 | |
| 3tki | S25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
| 4fti | H7K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
| 4hvi | 19S | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.444 | |
| 4i8v | BHF | Cytochrome P450 1A1 | 1.14.14.1 | 0.444 | |
| 4jbp | YPH | Aurora kinase A | 2.7.11.1 | 0.444 | |
| 4rrv | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.444 | |
| 5ap7 | SVE | Dual specificity protein kinase TTK | 2.7.12.1 | 0.444 | |
| 5bsg | NAP | Pyrroline-5-carboxylate reductase | / | 0.444 | |
| 4z35 | ON9 | Lysophosphatidic acid receptor 1 | / | 0.444 | |
| 4zj8 | SUV | Orexin receptor type 1 | / | 0.444 | |
| 1gjv | AGS | [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial | 2.7.11.4 | 0.443 | |
| 1ydt | IQB | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.443 | |
| 2cci | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 2vwi | ANP | Serine/threonine-protein kinase OSR1 | 2.7.11.1 | 0.443 | |
| 2w2l | NAD | D-mandelate dehydrogenase | / | 0.443 | |
| 3a99 | ANP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.443 | |
| 3cbl | STU | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.443 | |
| 3eem | 53V | Uncharacterized protein | / | 0.443 | |
| 3gcu | R48 | Mitogen-activated protein kinase 14 | / | 0.443 | |
| 3iok | 1P6 | Tyrosine-protein kinase JAK2 | / | 0.443 | |
| 3lgx | ATP | D-alanine--poly(phosphoribitol) ligase subunit 1 | / | 0.443 | |
| 3pls | ANP | Macrophage-stimulating protein receptor | 2.7.10.1 | 0.443 | |
| 3v5j | 0F2 | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.443 | |
| 4ccb | OFG | ALK tyrosine kinase receptor | 2.7.10.1 | 0.443 | |
| 4j97 | ACP | Fibroblast growth factor receptor 2 | / | 0.443 | |
| 4j98 | ACP | Fibroblast growth factor receptor 2 | / | 0.443 | |
| 4jbo | WPH | Aurora kinase A | 2.7.11.1 | 0.443 | |
| 4l3j | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.443 | |
| 4y12 | AGS | Serine/threonine-protein kinase PknG | 2.7.11.1 | 0.443 | |
| 1bx6 | BA1 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.442 | |
| 1csn | ATP | Casein kinase I homolog 1 | 2.7.11.1 | 0.442 | |
| 1jgt | APC | Carboxyethyl-arginine beta-lactam-synthase | 6.3.3.4 | 0.442 | |
| 2j9g | ADP | Biotin carboxylase | 6.3.4.14 | 0.442 | |
| 2pd7 | FAD | Vivid PAS protein VVD | / | 0.442 | |
| 2vgo | AD5 | Aurora kinase B-A | 2.7.11.1 | 0.442 | |
| 2x6d | X6D | Aurora kinase A | 2.7.11.1 | 0.442 | |
| 3dmh | SAM | Probable ribosomal RNA small subunit methyltransferase | / | 0.442 | |
| 4a06 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.442 | |
| 4bl5 | GFB | GDP-L-fucose synthase | 1.1.1.271 | 0.442 | |
| 4c57 | FEF | Cyclin-G-associated kinase | 2.7.11.1 | 0.442 | |
| 4ge7 | 0K5 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.442 | |
| 4ork | GDP | Bifunctional AAC/APH | 2.3.1 | 0.442 | |
| 5av2 | KMP | Death-associated protein kinase 1 | 2.7.11.1 | 0.442 | |
| 1ad5 | ANP | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.441 | |
| 1ol6 | ATP | Aurora kinase A | 2.7.11.1 | 0.441 | |
| 1phk | ATP | Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform | 2.7.11.19 | 0.441 | |
| 1u4d | DBQ | Activated CDC42 kinase 1 | / | 0.441 | |
| 1wlv | COA | Phenylacetic acid degradation protein PaaI | / | 0.441 | |
| 2an9 | GDP | Guanylate kinase | 2.7.4.8 | 0.441 | |
| 2g0n | GDP | Ras-related C3 botulinum toxin substrate 3 | / | 0.441 | |
| 2itq | ITQ | Epidermal growth factor receptor | 2.7.10.1 | 0.441 | |
| 2q61 | SF1 | Peroxisome proliferator-activated receptor gamma | / | 0.441 | |
| 2yx6 | ADP | Uncharacterized protein | / | 0.441 | |
| 2zjw | REF | Casein kinase II subunit alpha | 2.7.11.1 | 0.441 | |
| 3aez | GDP | Pantothenate kinase | 2.7.1.33 | 0.441 | |
| 3bu5 | ATP | Insulin receptor | 2.7.10.1 | 0.441 | |
| 3hrc | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.441 | |
| 3sc1 | 3S1 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.441 | |
| 3zew | STU | Ephrin type-B receptor 4 | 2.7.10.1 | 0.441 | |
| 3zhq | TPP | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.441 | |
| 3zon | IK1 | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.441 | |
| 4aqc | 88A | Tyrosine-protein kinase JAK2 | / | 0.441 | |
| 4bf2 | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.441 | |
| 4bfm | ANP | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.441 | |
| 4fsm | HK1 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 4gj3 | 0XP | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.441 | |
| 4xey | 1N1 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.441 | |
| 4ysw | NAI | Xanthine dehydrogenase/oxidase | / | 0.441 | |
| 4zrn | UPG | UDP-glucose 4-epimerase, putative | / | 0.441 | |
| 5aac | VGH | ALK tyrosine kinase receptor | 2.7.10.1 | 0.441 | |
| 5iqf | GDP | Bifunctional AAC/APH | 2.3.1 | 0.441 | |
| 1fin | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.440 | |
| 1i5a | ACP | Chemotaxis protein CheA | 2.7.13.3 | 0.440 | |
| 1pmn | 984 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.440 | |
| 1ztf | XYA | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.440 | |
| 2wxv | WXV | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 2x0r | NAD | Malate dehydrogenase | / | 0.440 | |
| 2y3r | TIR | TamL | / | 0.440 | |
| 2y4g | TIR | TamL | / | 0.440 | |
| 3a7j | ADP | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.440 | |
| 3cop | ADP | Glycogen synthase | 2.4.1.21 | 0.440 | |
| 3dd1 | 25D | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.440 | |
| 3fhy | ATP | Pyridoxal kinase | 2.7.1.35 | 0.440 | |
| 3tkh | 07S | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 3tnl | NAD | Shikimate dehydrogenase (NADP(+)) | / | 0.440 | |
| 3zc6 | VFC | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.440 | |
| 4ceg | ADP | Aurora kinase A | 2.7.11.1 | 0.440 | |
| 4dja | FAD | (6-4) photolyase | / | 0.440 | |
| 4hge | 15V | Tyrosine-protein kinase JAK2 | / | 0.440 | |
| 4ki8 | ADP | 60 kDa chaperonin | / | 0.440 | |
| 4nmb | FAD | Bifunctional protein PutA | / | 0.440 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.440 | |
| 4zas | TYD | CalS13 | / | 0.440 |