sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2pui | ADP | Methylthioribose kinase | 2.7.1.100 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2pui | ADP | Methylthioribose kinase | 2.7.1.100 | 1.000 | |
| 2pup | ADP | Methylthioribose kinase | 2.7.1.100 | 0.686 | |
| 2pul | ACP | Methylthioribose kinase | 2.7.1.100 | 0.638 | |
| 2pun | ACP | Methylthioribose kinase | 2.7.1.100 | 0.532 | |
| 2olc | ADP | Methylthioribose kinase | 2.7.1.100 | 0.531 | |
| 3itu | IBM | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.511 | |
| 3nrr | D16 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.501 | |
| 1x8b | 824 | Wee1-like protein kinase | 2.7.10.2 | 0.500 | |
| 3qly | 55V | Uncharacterized protein | / | 0.498 | |
| 5iqi | GNP | Bifunctional AAC/APH | 2.3.1 | 0.498 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.497 | |
| 4ele | 31I | Dihydrofolate reductase | / | 0.497 | |
| 2bkk | ADP | Aminoglycoside 3'-phosphotransferase | 2.7.1.95 | 0.494 | |
| 2pyw | ADP | Methylthioribose kinase | 2.7.1.100 | 0.492 | |
| 3eej | 53R | Uncharacterized protein | / | 0.491 | |
| 3fl8 | RAR | Dihydrofolate reductase | / | 0.491 | |
| 2a19 | ANP | Interferon-induced, double-stranded RNA-activated protein kinase | 2.7.11.1 | 0.490 | |
| 3qlx | QLR | Uncharacterized protein | / | 0.490 | |
| 3c0g | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.489 | |
| 1zth | ADP | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.488 | |
| 3eem | 53V | Uncharacterized protein | / | 0.488 | |
| 3sn7 | 540 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.487 | |
| 3u8h | BHP | Phospholipase A2, membrane associated | / | 0.486 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.486 | |
| 1zp9 | ATP | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.485 | |
| 4tx9 | AMZ | Phosphoribosyl isomerase A | / | 0.485 | |
| 3oro | AGS | Serine/threonine protein kinase | / | 0.484 | |
| 2jc6 | QPP | Calcium/calmodulin-dependent protein kinase type 1D | 2.7.11.17 | 0.483 | |
| 3ort | AGS | Serine/threonine protein kinase | / | 0.483 | |
| 4gb9 | 0WR | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.483 | |
| 1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.482 | |
| 4l9k | EHF | Serum albumin | / | 0.481 | |
| 1o6y | ACP | Serine/threonine-protein kinase PknB | 2.7.11.1 | 0.480 | |
| 2jiz | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.479 | |
| 2wue | KEK | 4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase | 3.7.1.17 | 0.479 | |
| 3qaq | QAQ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.479 | |
| 4fl2 | ANP | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.479 | |
| 5ftc | ADP | TPR domain protein | / | 0.479 | |
| 3wow | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.478 | |
| 4heu | 15J | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.478 | |
| 1soj | IBM | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.477 | |
| 2wuf | KEM | 4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase | 3.7.1.17 | 0.477 | |
| 4bbe | 3O4 | Tyrosine-protein kinase JAK2 | / | 0.477 | |
| 5iqd | GNP | Bifunctional AAC/APH | 2.3.1 | 0.477 | |
| 2wug | HPK | 4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase | 3.7.1.17 | 0.476 | |
| 3g4k | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.476 | |
| 3lu7 | IPX | Serum albumin | / | 0.476 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.476 | |
| 5iqa | GNP | Bifunctional AAC/APH | 2.3.1 | 0.476 | |
| 4crs | AGS | Serine/threonine-protein kinase N2 | 2.7.11.13 | 0.475 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.474 | |
| 1qkn | RAL | Estrogen receptor beta | / | 0.474 | |
| 2dcn | ADP | 2-keto-3-deoxy-gluconate kinase | / | 0.473 | |
| 3sni | 546 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.473 | |
| 3pwh | ZMA | Adenosine receptor A2a | / | 0.473 | |
| 1q9m | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.472 | |
| 3a99 | ANP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.472 | |
| 1mru | AGS | Serine/threonine-protein kinase PknB | 2.7.11.1 | 0.471 | |
| 3cgf | JNF | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.471 | |
| 4ddl | 0JQ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.471 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.471 | |
| 1j1c | ADP | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.470 | |
| 1j7l | ADP | Aminoglycoside 3'-phosphotransferase | 2.7.1.95 | 0.470 | |
| 2pmd | GNP | Translation initiation factor 2 subunit gamma | / | 0.470 | |
| 3s7a | 684 | Dihydrofolate reductase | 1.5.1.3 | 0.470 | |
| 4c1i | EH9 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.470 | |
| 4xcv | NDP | Probable hydroxyacid dehydrogenase protein | / | 0.470 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.469 | |
| 2vn0 | TDZ | Cytochrome P450 2C8 | / | 0.469 | |
| 3l08 | ZIG | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.469 | |
| 4jib | 1L6 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.469 | |
| 2a4z | BYM | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.468 | |
| 2idz | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.468 | |
| 3g4i | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.468 | |
| 3qv1 | NAD | Glyceraldehyde-3-phosphate dehydrogenase GAPA1, chloroplastic | 1.2.1.13 | 0.468 | |
| 4bge | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.468 | |
| 4elf | 35I | Dihydrofolate reductase | / | 0.468 | |
| 4hf4 | 15H | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.468 | |
| 1xon | PIL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.467 | |
| 2j0v | GDP | Rac-like GTP-binding protein ARAC7 | / | 0.467 | |
| 3iw1 | ASD | Steroid C26-monooxygenase | 1.14.13.141 | 0.467 | |
| 3tk3 | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.467 | |
| 4bfr | J82 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform | 2.7.1.153 | 0.467 | |
| 4lfi | GNP | Casein kinase II subunit alpha | 2.7.11.1 | 0.467 | |
| 4otp | ADP | Serine/threonine-protein kinase RIO1 | 2.7.11.1 | 0.467 | |
| 5bn4 | ANP | V-type ATP synthase alpha chain | / | 0.467 | |
| 1j7u | ANP | Aminoglycoside 3'-phosphotransferase | 2.7.1.95 | 0.466 | |
| 1psd | NAD | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.466 | |
| 1dnp | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.465 | |
| 2dr3 | ADP | UPF0273 protein PH0284 | / | 0.465 | |
| 3bi6 | 396 | Wee1-like protein kinase | 2.7.10.2 | 0.465 | |
| 3dat | MTX | Dihydrofolate reductase | / | 0.465 | |
| 3vx4 | ATP | Putative ABC transporter, ATP-binding protein ComA | / | 0.465 | |
| 4fjz | 4FJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.465 | |
| 1e90 | MYC | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.464 | |
| 2pml | ANP | Uncharacterized protein | / | 0.464 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 4ib4 | ERM | 5-hydroxytryptamine receptor 2B | / | 0.464 | |
| 2ok7 | FAD | Ferredoxin--NADP reductase, apicoplast | / | 0.463 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.463 | |
| 3uoz | NAP | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.463 | |
| 4bb6 | HD1 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.463 | |
| 4fjy | FJY | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.463 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.463 | |
| 4wbb | ADP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.463 | |
| 4yaf | 2AM | NADPH--cytochrome P450 reductase | / | 0.463 | |
| 3uza | T4G | Adenosine receptor A2a | / | 0.463 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.462 | |
| 1xkd | NAP | Isocitrate dehydrogenase [NADP] | / | 0.462 | |
| 1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.462 | |
| 2dt5 | NAD | Redox-sensing transcriptional repressor Rex | / | 0.462 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.462 | |
| 2ovy | PFJ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.462 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.462 | |
| 3tm0 | ANP | Aminoglycoside 3'-phosphotransferase | 2.7.1.95 | 0.462 | |
| 4bzo | 676 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.462 | |
| 4oav | ACP | 2-5A-dependent ribonuclease | 3.1.26 | 0.462 | |
| 5iqh | GNP | Bifunctional AAC/APH | 2.3.1 | 0.462 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 2acl | REA | Retinoic acid receptor RXR-alpha | / | 0.461 | |
| 2pr2 | DG1 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.461 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.461 | |
| 4ge4 | 0KE | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.461 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.461 | |
| 4n57 | ADP | APH(2'')-Id | / | 0.461 | |
| 5c6c | CMP | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.461 | |
| 2fzi | DH3 | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 3irm | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.460 | |
| 3ori | AGS | Serine/threonine protein kinase | / | 0.460 | |
| 4fwe | FAD | Lysine-specific histone demethylase 1B | 1 | 0.460 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 4muw | 2F4 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.460 | |
| 5iqf | GDP | Bifunctional AAC/APH | 2.3.1 | 0.460 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 1y2k | 7DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.459 | |
| 1zkn | IBM | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.459 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.459 | |
| 3igo | ANP | Calmodulin-domain protein kinase 1, putative | / | 0.459 | |
| 3zlm | ANP | Adenosine monophosphate-protein transferase NmFic | 2.7.7.n1 | 0.459 | |
| 4ej7 | ATP | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.459 | |
| 4elb | 34S | Dihydrofolate reductase | / | 0.459 | |
| 4fcb | 0T7 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.459 | |
| 4fl1 | ANP | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.459 | |
| 4jvb | 1M0 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.459 | |
| 4ork | GDP | Bifunctional AAC/APH | 2.3.1 | 0.459 | |
| 5k2a | ZMA | Adenosine receptor A2a | / | 0.459 | |
| 2h44 | 7CA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.458 | |
| 2in6 | 839 | Wee1-like protein kinase | 2.7.10.2 | 0.458 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 1yqj | 6NP | Mitogen-activated protein kinase 14 | / | 0.457 | |
| 2b36 | 5PP | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.457 | |
| 3ft8 | MOJ | Heat shock protein HSP 90-alpha | / | 0.457 | |
| 4bkj | STI | Epithelial discoidin domain-containing receptor 1 | 2.7.10.1 | 0.457 | |
| 4dqu | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.457 | |
| 4elg | 52J | Dihydrofolate reductase | / | 0.457 | |
| 4ix5 | ANP | Uncharacterized protein | / | 0.457 | |
| 4tzk | 641 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.457 | |
| 5iqe | GNP | Bifunctional AAC/APH | 2.3.1 | 0.457 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 1y2c | 3DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.456 | |
| 2hw2 | RFP | Rifampin ADP-ribosyl transferase | / | 0.456 | |
| 2ilt | NN1 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.456 | |
| 2jj2 | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.456 | |
| 2p2l | GDP | Ras-related C3 botulinum toxin substrate 1 | / | 0.456 | |
| 2pvl | P55 | Casein kinase II subunit alpha | 2.7.11.1 | 0.456 | |
| 2qk8 | MTX | Dihydrofolate reductase | / | 0.456 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.456 | |
| 2ydo | ADN | Adenosine receptor A2a | / | 0.456 | |
| 3ix9 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 3oq1 | 3OQ | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.456 | |
| 3w0s | ANP | Hygromycin-B 4-O-kinase | 2.7.1.163 | 0.456 | |
| 4a7c | E46 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.456 | |
| 4cuk | NAI | D-lactate dehydrogenase | / | 0.456 | |
| 5byl | GCP | Bifunctional AAC/APH | 2.3.1 | 0.456 | |
| 2v7a | 627 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.455 | |
| 3eel | 53T | Uncharacterized protein | / | 0.455 | |
| 4djw | 0KP | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
| 4yau | 2AM | NADPH--cytochrome P450 reductase | / | 0.455 | |
| 1cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 1tbb | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.454 | |
| 2dw4 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.454 | |
| 2jiz | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.454 | |
| 3aba | FLI | Cytochrome P450 | / | 0.454 | |
| 3czr | 3CZ | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.454 | |
| 3dds | 26B | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.454 | |
| 3qlw | N22 | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.454 | |
| 5ab6 | CAA | Nonspecific lipid-transfer protein, putative | / | 0.454 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 1so2 | 666 | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.453 | |
| 1xoq | ROF | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.453 | |
| 2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.453 | |
| 2x86 | ADP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.453 | |
| 3d5w | ADP | Serine/threonine-protein kinase PLK | / | 0.453 | |
| 3ibd | CPZ | Cytochrome P450 2B6 | 1.14.13 | 0.453 | |
| 3ml8 | ML8 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.453 | |
| 3q2m | CKI | Spectinomycin phosphotransferase | / | 0.453 | |
| 3zhq | TPP | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.453 | |
| 4ezj | 0SC | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.453 | |
| 4gg7 | 0J8 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.453 | |
| 4oew | 5IO | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.453 | |
| 4qkn | JMS | Alpha-ketoglutarate-dependent dioxygenase FTO | / | 0.453 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 1ewy | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.452 | |
| 1pkf | EPD | Epothilone C/D epoxidase | 1.14 | 0.452 | |
| 2fzh | DH1 | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 3hu2 | AGS | Transitional endoplasmic reticulum ATPase | 3.6.4.6 | 0.452 | |
| 3lj3 | WYE | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.452 | |
| 3m9v | TYD | FAD-dependent oxidoreductase | / | 0.452 | |
| 4k33 | ACP | Fibroblast growth factor receptor 3 | 2.7.10.1 | 0.452 | |
| 4m2x | TMQ | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 1eny | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.451 | |
| 1sq5 | ADP | Pantothenate kinase | 2.7.1.33 | 0.451 | |
| 1yc2 | NAD | NAD-dependent protein deacylase 2 | / | 0.451 | |
| 2ga9 | AGS | Poly(A) polymerase catalytic subunit | 2.7.7.19 | 0.451 | |
| 2jj1 | ADP | ATP synthase subunit alpha, mitochondrial | / | 0.451 | |
| 2jj1 | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.451 | |
| 3a4p | DFQ | Hepatocyte growth factor receptor | 2.7.10.1 | 0.451 | |
| 3a78 | 3EV | Vitamin D3 receptor | / | 0.451 | |
| 3ba6 | AN2 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.451 | |
| 3cr7 | PPS | Adenylyl-sulfate kinase | 2.7.1.25 | 0.451 | |
| 3eek | 53S | Uncharacterized protein | / | 0.451 | |
| 3gc9 | B45 | Mitogen-activated protein kinase 11 | 2.7.11.24 | 0.451 | |
| 3qft | NAP | NADPH--cytochrome P450 reductase | / | 0.451 | |
| 4anu | EM7 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.451 | |
| 4dit | 0KD | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.451 | |
| 4eev | L1X | Hepatocyte growth factor receptor | 2.7.10.1 | 0.451 | |
| 4i6g | FAD | Cryptochrome-2 | / | 0.451 | |
| 4l23 | X6K | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | / | 0.451 | |
| 4zas | TYD | CalS13 | / | 0.451 | |
| 1e7v | LY2 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.450 | |
| 1j3k | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.450 | |
| 1uyk | PUX | Heat shock protein HSP 90-alpha | / | 0.450 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 1xu9 | CPS | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.450 | |
| 1y2d | 4DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.450 | |
| 1zkl | IBM | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | 3.1.4.53 | 0.450 | |
| 2fm0 | M98 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.450 | |
| 2xk3 | XK3 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.450 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 2zza | FOL | Dihydrofolate reductase | / | 0.450 | |
| 3jyn | NDP | Quinone oxidoreductase | / | 0.450 | |
| 4h97 | 53S | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 4hle | 17V | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.450 | |
| 4itm | ATP | Tetraacyldisaccharide 4'-kinase | / | 0.450 | |
| 4jbt | ASD | Cytochrome P450 monooxygenase | / | 0.450 | |
| 1al7 | HST | Peroxisomal (S)-2-hydroxy-acid oxidase | 1.1.3.15 | 0.449 | |
| 1f5f | DHT | Sex hormone-binding globulin | / | 0.449 | |
| 1ir3 | ANP | Insulin receptor | 2.7.10.1 | 0.449 | |
| 1oyn | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.449 | |
| 1tdr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 2imk | GTX | AGAP009194-PA | / | 0.449 | |
| 3inv | C50 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.449 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.449 | |
| 3ntg | D72 | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.449 | |
| 3pdt | ADP | Myosin heavy chain kinase A | 2.7.11.7 | 0.449 | |
| 3qk0 | QK0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.449 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.449 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.449 | |
| 4lrj | ANP | Uncharacterized protein | / | 0.449 | |
| 4qml | ANP | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.449 | |
| 5dju | FMN | NPH1-2 | / | 0.449 | |
| 2hk9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.448 | |
| 2i4p | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.448 | |
| 3ae4 | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.448 | |
| 3hzi | ATP | Serine/threonine-protein kinase toxin HipA | / | 0.448 | |
| 4bew | CZA | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.448 | |
| 4bii | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.448 | |
| 4gg5 | 0J3 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.448 | |
| 5iub | CLR | Adenosine receptor A2a | / | 0.448 | |
| 3rey | XAC | Adenosine receptor A2a | / | 0.448 | |
| 3eml | ZMA | Adenosine receptor A2a | / | 0.448 | |
| 1aoe | GW3 | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1ia9 | ANP | Transient receptor potential cation channel subfamily M member 7 | 2.7.11.1 | 0.447 | |
| 1jol | FFO | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1tv8 | SAM | GTP 3',8-cyclase | 4.1.99.18 | 0.447 | |
| 2wey | EV1 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.447 | |
| 3cv9 | VDX | Vitamin D3 dihydroxylase | / | 0.447 | |
| 3k4s | 0MO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.447 | |
| 4ajw | VWN | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | 2.7.1.153 | 0.447 | |
| 4h1e | 10J | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 4nmb | FAD | Bifunctional protein PutA | / | 0.447 | |
| 4qem | HC4 | Phospholipase A2 VRV-PL-VIIIa | / | 0.447 | |
| 4xiw | AZM | Carbonic anhydrase, alpha type | / | 0.447 | |
| 4y9r | NAP | NADPH--cytochrome P450 reductase | / | 0.447 | |
| 1v35 | NAI | Enoyl-ACP reductase | / | 0.446 | |
| 2nnq | T4B | Fatty acid-binding protein, adipocyte | / | 0.446 | |
| 3g8d | ADP | Biotin carboxylase | 6.3.4.14 | 0.446 | |
| 3hcr | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.446 | |
| 3hko | ANP | Calcium/calmodulin-dependent protein kinase with a kinase domain and 2 calmodulin-like EF hands | / | 0.446 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.446 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 4bqg | 50Q | Heat shock protein HSP 90-alpha | / | 0.446 | |
| 4ekk | ANP | RAC-alpha serine/threonine-protein kinase | 2.7.11.1 | 0.446 | |
| 4fry | NAD | Putative signal-transduction protein with CBS domains | / | 0.446 | |
| 4gyi | ADP | Uncharacterized protein | / | 0.446 | |
| 4lva | 20M | Nicotinamide phosphoribosyltransferase | 2.4.2.12 | 0.446 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.445 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.445 | |
| 1e1m | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.445 | |
| 1jio | DEB | 6-deoxyerythronolide B hydroxylase | / | 0.445 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 1vzd | CB3 | Thymidylate synthase | / | 0.445 | |
| 1z6l | FAD | Polyamine oxidase FMS1 | / | 0.445 | |
| 2v1a | FMN | NPH1-1 | / | 0.445 | |
| 3c4z | ADP | Rhodopsin kinase | / | 0.445 | |
| 3fco | IIG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.445 | |
| 3ln1 | CEL | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.445 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.445 | |
| 3q4z | ANP | Serine/threonine-protein kinase PAK 1 | 2.7.11.1 | 0.445 | |
| 3uoy | NAP | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.445 | |
| 3vid | 4TT | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.445 | |
| 3zw3 | ZW3 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.445 | |
| 4flh | 14K | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.445 | |
| 4h6k | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.445 | |
| 4ia2 | BIV | Vitamin D3 receptor A | / | 0.445 | |
| 4kcf | AKM | FAD-dependent oxidoreductase | / | 0.445 | |
| 4ko8 | AGS | Transitional endoplasmic reticulum ATPase | 3.6.4.6 | 0.445 | |
| 4r1f | ADP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.445 | |
| 4y7c | NAP | NADPH--cytochrome P450 reductase | / | 0.445 | |
| 5iqb | GNP | Bifunctional AAC/APH | 2.3.1 | 0.445 | |
| 1q97 | ATP | Serine/threonine-protein kinase SKY1 | 2.7.11.1 | 0.444 | |
| 1uho | VDN | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.444 | |
| 1zid | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.444 | |
| 2gvc | FAD | Thiol-specific monooxygenase | 1.14.13 | 0.444 | |
| 2ouy | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.444 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 3iel | U5P | Ribonuclease TTHA0252 | 3.1 | 0.444 | |
| 3w5r | LOA | Vitamin D3 receptor | / | 0.444 | |
| 4b8u | IBK | 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase | 4.2.1.59 | 0.444 | |
| 4bva | T3 | Ketimine reductase mu-crystallin | 1.5.1.25 | 0.444 | |
| 4c3y | ANB | 3-ketosteroid dehydrogenase | / | 0.444 | |
| 4dja | FAD | (6-4) photolyase | / | 0.444 | |
| 4ful | 0VU | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.444 | |
| 4ku2 | MYA | 3-oxoacyl-[ACP] synthase III | / | 0.444 | |
| 4lv5 | ADP | Rhoptry protein 5B | / | 0.444 | |
| 4zme | ADN | Myosin heavy chain kinase A | 2.7.11.7 | 0.444 | |
| 1ad5 | ANP | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.443 | |
| 1dra | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1ia3 | TQ5 | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1qnf | HDF | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.443 | |
| 1u1f | 183 | Uridine phosphorylase | 2.4.2.3 | 0.443 | |
| 1x2h | LPA | Lipoate-protein ligase A | 6.3.1.20 | 0.443 | |
| 2c3i | IYZ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.443 | |
| 2j07 | HDF | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.443 | |
| 2owb | 626 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.443 | |
| 3aty | FMN | Prostaglandin F2a synthase | / | 0.443 | |
| 3cse | N22 | Uncharacterized protein | / | 0.443 | |
| 3inx | JZC | Heat shock protein HSP 90-alpha | / | 0.443 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 3pff | ADP | ATP-citrate synthase | 2.3.3.8 | 0.443 | |
| 3x04 | GNP | Phosphatidylinositol 5-phosphate 4-kinase type-2 beta | 2.7.1.149 | 0.443 | |
| 4ajd | F04 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.443 | |
| 4eft | EFT | Heat shock protein HSP 90-alpha | / | 0.443 | |
| 4h3j | 10W | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 4o0m | ATP | Circadian clock protein kinase KaiC | 2.7.11.1 | 0.443 | |
| 4zzi | 1NS | NAD-dependent protein deacetylase sirtuin-1 | 3.5.1 | 0.443 | |
| 5hs1 | VOR | Lanosterol 14-alpha demethylase | / | 0.443 | |
| 5k2b | ZMA | Adenosine receptor A2a | / | 0.443 | |
| 1h8h | ADP | ATP synthase subunit alpha, mitochondrial | / | 0.442 | |
| 1h8h | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.442 | |
| 1hwz | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.442 | |
| 1kvo | OAP | Phospholipase A2, membrane associated | / | 0.442 | |
| 1lp4 | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.442 | |
| 1s3y | TQT | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 2o65 | MYF | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.442 | |
| 2yke | YKE | Heat shock protein HSP 90-alpha | / | 0.442 | |
| 3fgo | CZA | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.442 | |
| 3of2 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 3r04 | UNQ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.442 | |
| 3th8 | TH9 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.442 | |
| 3wo1 | ADP | Alanine--anticapsin ligase | / | 0.442 | |
| 4acg | 6LQ | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.442 | |
| 4bqp | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 4ge7 | 0K5 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.442 | |
| 4izy | 1J2 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.442 | |
| 4jlm | 1NN | Deoxycytidine kinase | 2.7.1.74 | 0.442 | |
| 4ktl | 1CQ | Cytochrome P450 | / | 0.442 | |
| 4l8u | 9AZ | Serum albumin | / | 0.442 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.442 | |
| 4qpm | ADP | Mitotic checkpoint serine/threonine-protein kinase BUB1 | 2.7.11.1 | 0.442 | |
| 5g53 | NEC | Adenosine receptor A2a | / | 0.442 | |
| 5k2c | ZMA | Adenosine receptor A2a | / | 0.442 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 1kqu | BR4 | Phospholipase A2, membrane associated | / | 0.441 | |
| 1n4h | REA | Nuclear receptor ROR-beta | / | 0.441 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.441 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.441 | |
| 2bik | BI1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.441 | |
| 2gnf | Y27 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.441 | |
| 2jbl | SMA | Reaction center protein L chain | / | 0.441 | |
| 2ozo | ANP | Tyrosine-protein kinase ZAP-70 | 2.7.10.2 | 0.441 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.441 | |
| 2w6m | OA1 | Biotin carboxylase | 6.3.4.14 | 0.441 | |
| 2wsi | FAD | FAD synthase | 2.7.7.2 | 0.441 | |
| 2yg4 | FAD | Putrescine oxidase | / | 0.441 | |
| 3e8e | G98 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.441 | |
| 3hu3 | AGS | Transitional endoplasmic reticulum ATPase | 3.6.4.6 | 0.441 | |
| 3jqp | A2P | Ferredoxin--NADP reductase, apicoplast | / | 0.441 | |
| 3jwm | 5WB | Dihydrofolate reductase | / | 0.441 | |
| 3kjs | DQ1 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.441 | |
| 3s2a | 2NQ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.441 | |
| 4b5p | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.441 | |
| 4btj | ADP | Tau-tubulin kinase 1 | 2.7.11.1 | 0.441 | |
| 4dan | 2FA | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.441 | |
| 4fad | 0TB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.441 | |
| 4fl3 | ANP | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.441 | |
| 4icy | FAD | PgaE | / | 0.441 | |
| 4jrn | ANP | Rhoptry kinase family protein | / | 0.441 | |
| 4kf1 | HT5 | Aryldialkylphosphatase | 3.1.8.1 | 0.441 | |
| 4mvh | 2F5 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.441 | |
| 1bsv | NDP | GDP-L-fucose synthase | / | 0.440 | |
| 1kl2 | FON | Serine hydroxymethyltransferase | / | 0.440 | |
| 1zyd | ATP | eIF-2-alpha kinase GCN2 | / | 0.440 | |
| 2ph5 | NAD | Homospermidine synthase | / | 0.440 | |
| 2y3r | TIR | TamL | / | 0.440 | |
| 3b9l | AZZ | Serum albumin | / | 0.440 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 3k9u | ACO | Spermidine N(1)-acetyltransferase | / | 0.440 | |
| 3lki | ATP | Fructokinase | / | 0.440 | |
| 3nga | 3NG | Casein kinase II subunit alpha | 2.7.11.1 | 0.440 | |
| 3opd | HIE | Heat shock protein 83 | / | 0.440 | |
| 3qpn | PFK | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.440 | |
| 3zdf | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.440 | |
| 3zux | TCH | Transporter | / | 0.440 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.440 | |
| 4anv | 751 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 4h6r | FDA | Proline dehydrogenase | / | 0.440 | |
| 4hfr | 14M | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.440 | |
| 4j1r | I5R | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.440 | |
| 4jia | 1K3 | Tyrosine-protein kinase JAK2 | / | 0.440 | |
| 4llk | MEW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.440 | |
| 4r21 | STR | Cytochrome P450 family 17 polypeptide 2 | / | 0.440 | |
| 4u9z | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.440 | |
| 4y12 | AGS | Serine/threonine-protein kinase PknG | 2.7.11.1 | 0.440 | |
| 5hi6 | MTX | Dihydrofolate reductase | / | 0.440 | |
| 5hwq | CAA | Hydroxymethylglutaryl-CoA synthase | / | 0.440 |