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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2fgiPD1Fibroblast growth factor receptor 1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2fgiPD1Fibroblast growth factor receptor 1/1.000
4nka2K7Fibroblast growth factor receptor 1/0.643
4nks2M2Fibroblast growth factor receptor 1/0.609
4f640S8Fibroblast growth factor receptor 1/0.607
3b8r887Vascular endothelial growth factor receptor 22.7.10.10.603
4nk92K5Fibroblast growth factor receptor 1/0.603
3js2VM1Fibroblast growth factor receptor 1/0.560
3qlfPD5Proto-oncogene tyrosine-protein kinase Src2.7.10.20.560
3cjgKIMVascular endothelial growth factor receptor 22.7.10.10.559
4f630S7Fibroblast growth factor receptor 1/0.549
4j97ACPFibroblast growth factor receptor 2/0.548
4dggI76Proto-oncogene tyrosine-protein kinase Src2.7.10.20.546
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.545
2p2h994Vascular endothelial growth factor receptor 22.7.10.10.545
3qlg1N1Proto-oncogene tyrosine-protein kinase Src2.7.10.20.545
4bidIE8Mitogen-activated protein kinase kinase kinase 52.7.11.250.541
3mvl38PMitogen-activated protein kinase 14/0.537
3vs6VSHTyrosine-protein kinase HCK2.7.10.20.536
4mxoDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.536
4qmnDB8Serine/threonine-protein kinase 242.7.11.10.536
4bc6XZNSerine/threonine-protein kinase 102.7.11.10.535
1qpdSTUTyrosine-protein kinase Lck2.7.10.20.534
1zyjBI5Mitogen-activated protein kinase 14/0.534
2pwlACPFibroblast growth factor receptor 2/0.534
3vrzVRZTyrosine-protein kinase HCK2.7.10.20.534
2itzIREEpidermal growth factor receptor2.7.10.10.531
3vs7KS1Tyrosine-protein kinase HCK2.7.10.20.529
3b2w9NHTyrosine-protein kinase Lck2.7.10.20.528
2c0tL3GTyrosine-protein kinase HCK2.7.10.20.525
4fic0ULProto-oncogene tyrosine-protein kinase Src2.7.10.20.525
4mxyDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.525
4mxzDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.525
4qmxH8HSerine/threonine-protein kinase 242.7.11.10.525
2bdf24AProto-oncogene tyrosine-protein kinase Src2.7.10.20.523
4anqVGHALK tyrosine kinase receptor2.7.10.10.523
1agwSU2Fibroblast growth factor receptor 1/0.522
1oecAA2Fibroblast growth factor receptor 2/0.521
4xli1N1Abelson tyrosine-protein kinase 22.7.10.20.521
3zewSTUEphrin type-B receptor 42.7.10.10.519
1qpePP2Tyrosine-protein kinase Lck2.7.10.20.518
3vjoANPEpidermal growth factor receptor2.7.10.10.518
4jr3KJREpidermal growth factor receptor2.7.10.10.518
2bdjHETProto-oncogene tyrosine-protein kinase Src2.7.10.20.517
2pvyACPFibroblast growth factor receptor 2/0.517
3s4qNK0Mitogen-activated protein kinase 14/0.517
4gmy0X5Tyrosine-protein kinase JAK2/0.517
2itqITQEpidermal growth factor receptor2.7.10.10.516
3vs3VSETyrosine-protein kinase HCK2.7.10.20.516
2r0uM54Serine/threonine-protein kinase Chk12.7.11.10.515
2vwx7X4Ephrin type-B receptor 42.7.10.10.515
4k110J9Proto-oncogene tyrosine-protein kinase Src2.7.10.20.515
1m17AQ4Epidermal growth factor receptor2.7.10.10.514
4ansVGHALK tyrosine kinase receptor2.7.10.10.514
5aacVGHALK tyrosine kinase receptor2.7.10.10.514
2hog710Serine/threonine-protein kinase Chk12.7.11.10.513
2py3ACPFibroblast growth factor receptor 2/0.512
3c7qXINVascular endothelial growth factor receptor 22.7.10.10.511
4ic7ANPMitogen-activated protein kinase 72.7.11.240.511
2c0iL1GTyrosine-protein kinase HCK2.7.10.20.510
2zv9PP2Tyrosine-protein kinase Lyn2.7.10.20.509
3nww3NWMitogen-activated protein kinase 14/0.509
3vs4VSFTyrosine-protein kinase HCK2.7.10.20.509
2of4979Tyrosine-protein kinase Lck2.7.10.20.506
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.505
2of2547Tyrosine-protein kinase Lck2.7.10.20.505
2xm9LWHSerine/threonine-protein kinase Chk22.7.11.10.505
2zva1N1Tyrosine-protein kinase Lyn2.7.10.20.505
1finATPCyclin-dependent kinase 22.7.11.220.504
1yolS03Proto-oncogene tyrosine-protein kinase Src2.7.10.20.504
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.504
3a7hATPSerine/threonine-protein kinase 242.7.11.10.504
3ac5KZMTyrosine-protein kinase Lck2.7.10.20.503
4jq8KJ8Epidermal growth factor receptor2.7.10.10.503
3ue4DB8Tyrosine-protein kinase ABL12.7.10.20.502
4f650S9Fibroblast growth factor receptor 1/0.502
1yi3LY2Serine/threonine-protein kinase pim-12.7.11.10.501
2i0ePDSProtein kinase C beta type2.7.11.130.501
5e8xSTUTGF-beta receptor type-12.7.11.300.501
1qcfPP1Tyrosine-protein kinase HCK2.7.10.20.500
2ittAEEEpidermal growth factor receptor2.7.10.10.500
1wvxBD4Death-associated protein kinase 12.7.11.10.499
2vx17X8Ephrin type-B receptor 42.7.10.10.499
2zybKSLTyrosine-protein kinase Lck2.7.10.20.499
5amnDTQProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.499
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.498
4bibIEOMitogen-activated protein kinase kinase kinase 52.7.11.250.498
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.498
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.498
2vx07X7Ephrin type-B receptor 42.7.10.10.497
4fob0USALK tyrosine kinase receptor2.7.10.10.497
4jrvKJVEpidermal growth factor receptor2.7.10.10.497
1bygSTUTyrosine-protein kinase CSK/0.496
2c6eHPMAurora kinase A2.7.11.10.496
2ivuZD6Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.496
2vwy7X5Ephrin type-B receptor 42.7.10.10.496
3t8oATPRhodopsin kinase/0.496
3w33W19Epidermal growth factor receptor2.7.10.10.496
4btkDTQTau-tubulin kinase 12.7.11.10.496
4mxxDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.496
2hk51BMTyrosine-protein kinase HCK2.7.10.20.495
3vryB43Tyrosine-protein kinase HCK2.7.10.20.495
4jia1K3Tyrosine-protein kinase JAK2/0.495
1u4dDBQActivated CDC42 kinase 1/0.494
2v7a627Tyrosine-protein kinase ABL12.7.10.20.494
4y93746Tyrosine-protein kinase/0.494
1y57MPZProto-oncogene tyrosine-protein kinase Src2.7.10.20.493
4ftiH7KSerine/threonine-protein kinase Chk12.7.11.10.493
4gk4L90Ephrin type-A receptor 32.7.10.10.493
1ywrLI9Mitogen-activated protein kinase 14/0.492
2gcdSTUSerine/threonine-protein kinase TAO22.7.11.10.492
2vwz7X6Ephrin type-B receptor 42.7.10.10.492
2zm1KSFTyrosine-protein kinase Lck2.7.10.20.492
3uvqFS8Mitogen-activated protein kinase 14/0.492
4dfl0K0Tyrosine-protein kinase SYK2.7.10.20.492
4mcv29KProto-oncogene tyrosine-protein kinase Src2.7.10.20.492
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.491
3dt1P40Mitogen-activated protein kinase 14/0.491
3flsFLSMitogen-activated protein kinase 14/0.491
3hllI45Mitogen-activated protein kinase 14/0.491
4ih8B43Calmodulin-domain protein kinase 1/0.491
2itpAEEEpidermal growth factor receptor2.7.10.10.490
2j0k4STFocal adhesion kinase 12.7.10.20.490
2pz5ACPFibroblast growth factor receptor 2/0.490
2pzpACPFibroblast growth factor receptor 2/0.490
2q0bACPFibroblast growth factor receptor 2/0.490
2yfxVGHALK tyrosine kinase receptor2.7.10.10.490
3vs2VSBTyrosine-protein kinase HCK2.7.10.20.490
3vs5VSGTyrosine-protein kinase HCK2.7.10.20.490
4aa5NQBMitogen-activated protein kinase 14/0.490
5aaaVGHALK tyrosine kinase receptor2.7.10.10.490
3a4oSTUTyrosine-protein kinase Lyn2.7.10.20.489
2etm7PYFocal adhesion kinase 12.7.10.20.488
3bhy7CPDeath-associated protein kinase 3/0.488
3h9f92MDual specificity protein kinase TTK2.7.12.10.488
3l8p0CEAngiopoietin-1 receptor2.7.10.10.488
4gk2L66Ephrin type-A receptor 32.7.10.10.488
4gk3L87Ephrin type-A receptor 32.7.10.10.488
2y6o1N1Ephrin type-A receptor 42.7.10.10.487
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.487
3w2sW2REpidermal growth factor receptor2.7.10.10.487
4hvh19RTyrosine-protein kinase JAK32.7.10.20.487
4lggVGGProto-oncogene tyrosine-protein kinase Src2.7.10.20.487
4xey1N1Tyrosine-protein kinase ABL12.7.10.20.487
2f4jVX6Tyrosine-protein kinase ABL12.7.10.20.486
3b2tM33Fibroblast growth factor receptor 2/0.486
4cd0AWJALK tyrosine kinase receptor2.7.10.10.486
4dce0JFALK tyrosine kinase receptor2.7.10.10.485
4k1b1OCSerine/threonine-protein kinase pim-12.7.11.10.485
4z34ON7Lysophosphatidic acid receptor 1/0.485
2bujSTUSerine/threonine-protein kinase 16/0.484
2qo9ANPEphrin type-A receptor 32.7.10.10.484
2xp2VGHALK tyrosine kinase receptor2.7.10.10.484
3iphG11Mitogen-activated protein kinase 14/0.484
4fsqHK3Serine/threonine-protein kinase Chk12.7.11.10.483
4ftm1HKSerine/threonine-protein kinase Chk12.7.11.10.483
4jq7KJQEpidermal growth factor receptor2.7.10.10.483
2qhm7CSSerine/threonine-protein kinase Chk12.7.11.10.482
3ncgBK1Calmodulin-domain protein kinase 1, putative/0.482
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.482
4nj32KDCyclin-dependent kinase 22.7.11.220.482
3ad6KSCTyrosine-protein kinase Lck2.7.10.20.481
3f5p741Insulin-like growth factor 1 receptor2.7.10.10.481
3hl7I47Mitogen-activated protein kinase 14/0.481
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.480
3lcdBDYMacrophage colony-stimulating factor 1 receptor2.7.10.10.480
4id71G0Activated CDC42 kinase 1/0.480
2ivvPP1Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.479
4e4m0NHTyrosine-protein kinase JAK2/0.479
1m7qDQOMitogen-activated protein kinase 14/0.478
2vww7X2Ephrin type-B receptor 42.7.10.10.478
3ac3KSHTyrosine-protein kinase Lck2.7.10.20.478
3fklFKLMitogen-activated protein kinase 14/0.478
3mwuBK3Calmodulin-domain protein kinase 1, putative/0.478
3uvp048Mitogen-activated protein kinase 14/0.478
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.478
4fstHK4Serine/threonine-protein kinase Chk12.7.11.10.478
2ghmLICMitogen-activated protein kinase 14/0.477
2itnANPEpidermal growth factor receptor2.7.10.10.477
2vwu7X1Ephrin type-B receptor 42.7.10.10.477
3fln3FNMitogen-activated protein kinase 14/0.477
3tucFPWTyrosine-protein kinase SYK2.7.10.20.477
4aa4QC0Mitogen-activated protein kinase 14/0.477
4fg7ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.477
4fnzNZFALK tyrosine kinase receptor2.7.10.10.477
4lgh0JNProto-oncogene tyrosine-protein kinase Src2.7.10.20.477
1w84L12Mitogen-activated protein kinase 14/0.476
2itwITQEpidermal growth factor receptor2.7.10.10.476
3lctADPALK tyrosine kinase receptor2.7.10.10.476
4eqcXR1Serine/threonine-protein kinase PAK 12.7.11.10.476
4lopSB4Mitogen-activated protein kinase 14/0.476
4otwDB8Receptor tyrosine-protein kinase erbB-32.7.10.10.476
2h8hH8HProto-oncogene tyrosine-protein kinase Src2.7.10.20.475
3vjnANPEpidermal growth factor receptor2.7.10.10.475
4f9wLM4Mitogen-activated protein kinase 14/0.475
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.475
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.474
3emg685Tyrosine-protein kinase SYK2.7.10.20.474
3fmn530Mitogen-activated protein kinase 14/0.474
3gubGUBDeath-associated protein kinase 12.7.11.10.474
3l8xN4DMitogen-activated protein kinase 14/0.474
4o0rX4ZSerine/threonine-protein kinase PAK 12.7.11.10.474
4qmzB49Serine/threonine-protein kinase 242.7.11.10.474
4yuqKS1Calmodulin-like domain protein kinase/0.474
4yzcSTUSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.474
1ouy094Mitogen-activated protein kinase 14/0.473
2c0oL2GTyrosine-protein kinase HCK2.7.10.20.473
2f2cAP9Cyclin-dependent kinase 62.7.11.220.473
3flwFLWMitogen-activated protein kinase 14/0.473
4aotGW8Serine/threonine-protein kinase 102.7.11.10.473
5e8wSTUTGF-beta receptor type-12.7.11.300.473
3bbtFMMReceptor tyrosine-protein kinase erbB-42.7.10.10.472
3flyFLYMitogen-activated protein kinase 14/0.472
4ftcH6KSerine/threonine-protein kinase Chk12.7.11.10.472
4ftkH9KSerine/threonine-protein kinase Chk12.7.11.10.472
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.471
2qoqANPEphrin type-A receptor 32.7.10.10.471
3pjcPJCTyrosine-protein kinase JAK32.7.10.20.471
3w1f1O5Dual specificity protein kinase TTK2.7.12.10.471
3ztxZTXAurora kinase B-A2.7.11.10.471
2xclANPPhosphoribosylamine--glycine ligase/0.470
4c4h7RODual specificity protein kinase TTK2.7.12.10.470
4i231C9Epidermal growth factor receptor2.7.10.10.470
1q4l679Glycogen synthase kinase-3 beta2.7.11.260.469
2balPQAMitogen-activated protein kinase 14/0.469
2j0j4STFocal adhesion kinase 12.7.10.20.469
2vgoAD5Aurora kinase B-A2.7.11.10.469
2yirYIRSerine/threonine-protein kinase Chk22.7.11.10.469
3ac1KZITyrosine-protein kinase Lck2.7.10.20.469
3c4xATPRhodopsin kinase/0.469
3icrCOACoenzyme A disulfide reductase/0.469
3iw4LW4Protein kinase C alpha type2.7.11.130.469
3q3b55EGlycogen synthase kinase-3 beta2.7.11.260.469
3w2o03PEpidermal growth factor receptor2.7.10.10.469
5aabVGHALK tyrosine kinase receptor2.7.10.10.469
1hpoUNIGag-Pol polyprotein3.4.23.160.468
2xyuQ9GEphrin type-A receptor 42.7.10.10.468
2yn8STUEphrin type-B receptor 42.7.10.10.468
3gstGPRGlutathione S-transferase Mu 12.5.1.180.468
3sgx0FWDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.468
3vid4TTVascular endothelial growth factor receptor 22.7.10.10.468
4b8mVX6Aurora kinase B-A2.7.11.10.468
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.468
4ftlH0KSerine/threonine-protein kinase Chk12.7.11.10.468
4qmlANPSerine/threonine-protein kinase 242.7.11.10.468
2c475IDCasein kinase I isoform gamma-2/0.467
2vrx447Aurora kinase B-A2.7.11.10.467
2wmxZY6Serine/threonine-protein kinase Chk12.7.11.10.467
2xa4AZ5Tyrosine-protein kinase JAK2/0.467
2ym3YM3Serine/threonine-protein kinase Chk12.7.11.10.467
3gfeP37Mitogen-activated protein kinase 14/0.467
3hp552PMitogen-activated protein kinase 14/0.467
3uyt0CKCasein kinase I isoform delta2.7.11.10.467
4dlj6RGMitogen-activated protein kinase 14/0.467
4g2fC07Ephrin type-A receptor 32.7.10.10.467
4kiq1RAMitogen-activated protein kinase 14/0.467
4l7sG7KTyrosine-protein kinase ITK/TSK2.7.10.20.467
4wkqIREEpidermal growth factor receptor2.7.10.10.467
1xwsBI1Serine/threonine-protein kinase pim-12.7.11.10.466
2csnCKICasein kinase I homolog 12.7.11.10.466
2xvdAS6Ephrin type-B receptor 42.7.10.10.466
2yitYITSerine/threonine-protein kinase Chk22.7.11.10.466
3f69XDRSerine/threonine-protein kinase PknB2.7.11.10.466
3gc9B45Mitogen-activated protein kinase 112.7.11.240.466
3mpaSB2Mitogen-activated protein kinase 14/0.466
3qk0QK0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.466
3roc29AMitogen-activated protein kinase 14/0.466
4aacAAVMitogen-activated protein kinase 14/0.466
4fnyI3KALK tyrosine kinase receptor2.7.10.10.466
4wboANWRhodopsin kinase/0.466
1hncGDNGlutathione S-transferase Mu 22.5.1.180.465
2bfyH1NAurora kinase B-A2.7.11.10.465
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.465
2eb3ANPEpidermal growth factor receptor2.7.10.10.465
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.465
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.465
4fsnA58Serine/threonine-protein kinase Chk12.7.11.10.465
1oiyN41Cyclin-dependent kinase 22.7.11.220.464
2c3kABOSerine/threonine-protein kinase Chk12.7.11.10.464
2xikJ60Serine/threonine-protein kinase 252.7.11.10.464
4ftn2HKSerine/threonine-protein kinase Chk12.7.11.10.464
4l425FIRibosomal protein S6 kinase beta-12.7.11.10.464
1nvrSTUSerine/threonine-protein kinase Chk12.7.11.10.463
2x2kX2KProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.463
2ym6YM6Serine/threonine-protein kinase Chk12.7.11.10.463
3fmjFMJMitogen-activated protein kinase 14/0.463
3tkh07SSerine/threonine-protein kinase Chk12.7.11.10.463
4hgl0YOCasein kinase I isoform gamma-32.7.11.10.463
4hjoAQ4Epidermal growth factor receptor2.7.10.10.463
1eh4IC1Casein kinase I homolog 12.7.11.10.462
2j0m4STFocal adhesion kinase 12.7.10.20.462
2j4z626Aurora kinase A2.7.11.10.462
2ycrHCWSerine/threonine-protein kinase Chk22.7.11.10.462
3bu5ATPInsulin receptor2.7.10.10.462
3ckxSTUSerine/threonine-protein kinase 242.7.11.10.462
3ha85JZMitogen-activated protein kinase 14/0.462
4c62XWWTyrosine-protein kinase JAK2/0.462
2jedLG8Protein kinase C theta type2.7.11.130.461
2wmwZYWSerine/threonine-protein kinase Chk12.7.11.10.461
3ac2KSETyrosine-protein kinase Lck2.7.10.20.461
3fi4FI4Mitogen-activated protein kinase 14/0.461
3fskRO6Mitogen-activated protein kinase 14/0.461
3jxwLXGSerine/threonine-protein kinase pim-12.7.11.10.461
3s2a2NQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.461
3vs0VS0Tyrosine-protein kinase HCK2.7.10.20.461
4b99R4LMitogen-activated protein kinase 72.7.11.240.461
4hvg19QTyrosine-protein kinase JAK32.7.10.20.461
5ajqDB8Serine/threonine-protein kinase 102.7.11.10.461
2chlDKICasein kinase I isoform gamma-32.7.11.10.460
2vd5BI8Myotonin-protein kinase2.7.11.10.460
2xf04UBSerine/threonine-protein kinase Chk12.7.11.10.460
3fl4FL4Mitogen-activated protein kinase 14/0.460
3mpt1GKMitogen-activated protein kinase 14/0.460
4bb432WEphrin type-B receptor 42.7.10.10.460
4d9t0JGRibosomal protein S6 kinase alpha-32.7.11.10.460
1ie4T44Transthyretin/0.459
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.459
1uu8BI13-phosphoinositide-dependent protein kinase 12.7.11.10.459
2fumMIXSerine/threonine-protein kinase PknB2.7.11.10.459
2gstGPSGlutathione S-transferase Mu 12.5.1.180.459
2zm4KSMTyrosine-protein kinase Lck2.7.10.20.459
3ambVX6cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.459
3vo30KFVascular endothelial growth factor receptor 22.7.10.10.459
3wi6YRZMAP kinase-activated protein kinase 22.7.11.10.459
4aojV4ZHigh affinity nerve growth factor receptor2.7.10.10.459
4c3pACPAurora kinase A2.7.11.10.459
4fsyHK7Serine/threonine-protein kinase Chk12.7.11.10.459
4hni16WCasein kinase I isoform epsilon2.7.11.10.459
4hvi19STyrosine-protein kinase JAK32.7.10.20.459
4joa3DKALK tyrosine kinase receptor2.7.10.10.459
4qmuSKESerine/threonine-protein kinase 242.7.11.10.459
4qo9627Serine/threonine-protein kinase 242.7.11.10.459
2brbPFQSerine/threonine-protein kinase Chk12.7.11.10.458
2ym5YM5Serine/threonine-protein kinase Chk12.7.11.10.458
2zb0GK3Mitogen-activated protein kinase 14/0.458
3fzpAGSProtein-tyrosine kinase 2-beta2.7.10.20.458
3vs1VSATyrosine-protein kinase HCK2.7.10.20.458
3zokNAD3-dehydroquinate synthase, chloroplastic4.2.3.40.458
4flh14KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.458
4fsuHK5Serine/threonine-protein kinase Chk12.7.11.10.458
4hnf16WCasein kinase I isoform delta2.7.11.10.458
4i22IREEpidermal growth factor receptor2.7.10.10.458
5auwQUEDeath-associated protein kinase 12.7.11.10.458
5dr9SKEAurora kinase A2.7.11.10.458
1ove358Mitogen-activated protein kinase 14/0.457
2j7t274Serine/threonine-protein kinase 102.7.11.10.457
2pzrACPFibroblast growth factor receptor 2/0.457
2wouZZFTGF-beta receptor type-12.7.11.300.457
2xru400Aurora kinase A2.7.11.10.457
3a2oKNJGag-Pol polyprotein3.4.23.160.457
3oom507Activin receptor type-12.7.11.300.457
4aw530KEphrin type-B receptor 42.7.10.10.457
4e37NDPCatalase1.11.1.60.457
4k33ACPFibroblast growth factor receptor 32.7.10.10.457
4kin1M8Mitogen-activated protein kinase 14/0.457
2e9oA58Serine/threonine-protein kinase Chk12.7.11.10.456
2hxq373Serine/threonine-protein kinase Chk12.7.11.10.456
3ezvEZVCyclin-dependent kinase 22.7.11.220.456
3fmkFMKMitogen-activated protein kinase 14/0.456
3itzP66Mitogen-activated protein kinase 14/0.456
4ft9H4KSerine/threonine-protein kinase Chk12.7.11.10.456
4kba1QMCasein kinase I isoform delta2.7.11.10.456
2gs7ANPEpidermal growth factor receptor2.7.10.10.455
2izuP01Casein kinase I isoform gamma-32.7.11.10.455
3p23ADPSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.455
4kip1R9Mitogen-activated protein kinase 14/0.455
4z35ON9Lysophosphatidic acid receptor 1/0.455
2ayp43ASerine/threonine-protein kinase Chk12.7.11.10.454
2wmuZYUSerine/threonine-protein kinase Chk12.7.11.10.454
3lpbNVBTyrosine-protein kinase JAK2/0.454
3umxQ18Serine/threonine-protein kinase pim-12.7.11.10.454
4bfmANPMaternal embryonic leucine zipper kinase2.7.11.10.454
4iebANPCalmodulin-domain protein kinase 1/0.454
4loqSB4Mitogen-activated protein kinase 14/0.454
4mbl26LSerine/threonine-protein kinase pim-12.7.11.10.454
4o0sADNAurora kinase A2.7.11.10.454
1q3wATUGlycogen synthase kinase-3 beta2.7.11.260.453
1sm2STUTyrosine-protein kinase ITK/TSK2.7.10.20.453
1vjy460TGF-beta receptor type-12.7.11.300.453
1zz2B11Mitogen-activated protein kinase 14/0.453
2acxANPG protein-coupled receptor kinase 62.7.11.160.453
2brgDFYSerine/threonine-protein kinase Chk12.7.11.10.453
2c7xNRBCytochrome P450 monooxygenase PikC/0.453
2ckeIQUDeath-associated protein kinase 2/0.453
2j0lANPFocal adhesion kinase 12.7.10.20.453
2wmsZYSSerine/threonine-protein kinase Chk12.7.11.10.453
3fmh533Mitogen-activated protein kinase 14/0.453
4c4g7RODual specificity protein kinase TTK2.7.12.10.453
4ftu7HKSerine/threonine-protein kinase Chk12.7.11.10.453
5d12G97Proto-oncogene tyrosine-protein kinase Src2.7.10.20.453
3kf7L9GMitogen-activated protein kinase 14/0.452
3lijANPCalcium/calmodulin dependent protein kinase with a kinase domain and 4 calmodulin like EF hands/0.452
3tmz06XCytochrome P450 2B41.14.14.10.452
3vquO22Dual specificity protein kinase TTK2.7.12.10.452
4l2iFADElectron transfer flavoprotein alpha/beta-subunit/0.452
4mxaBK7Calmodulin-like domain protein kinase isoenzyme gamma, related/0.452
1ouk084Mitogen-activated protein kinase 14/0.451
1q41IXMGlycogen synthase kinase-3 beta2.7.11.260.451
2br1PFPSerine/threonine-protein kinase Chk12.7.11.10.451
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.451
2wmtZYTSerine/threonine-protein kinase Chk12.7.11.10.451
2xynVX6Abelson tyrosine-protein kinase 22.7.10.20.451
3a62STURibosomal protein S6 kinase beta-12.7.11.10.451
3ekv478Gag-Pol polyprotein3.4.23.160.451
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.451
3uibSB2Putative mitogen-activated protein kinase/0.451
4bcqTJFCyclin-dependent kinase 22.7.11.220.451
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.451
4k2xFADPolyketide oxygenase/hydroxylase/0.451
4l3l5FIRibosomal protein S6 kinase beta-12.7.11.10.451
4lm5Q17Serine/threonine-protein kinase pim-12.7.11.10.451
4nfn2KCTau-tubulin kinase 12.7.11.10.451
1nxkSTUMAP kinase-activated protein kinase 22.7.11.10.450
1t7i017Gag-Pol polyprotein3.4.23.160.450
1uvrBI83-phosphoinositide-dependent protein kinase 12.7.11.10.450
1yvj4STTyrosine-protein kinase JAK32.7.10.20.450
2ghlLIBMitogen-activated protein kinase 14/0.450
2x2lX2LProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.450
2x7gPVBSRSF protein kinase 22.7.11.10.450
3bqr4RBDeath-associated protein kinase 3/0.450
3oxv478Gag-Pol polyprotein3.4.23.160.450
4ct1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.450
5k2cZMAAdenosine receptor A2a/0.450
2bilBI1Serine/threonine-protein kinase pim-12.7.11.10.449
2h96893Mitogen-activated protein kinase 82.7.11.240.449
2i40BLZCyclin-dependent kinase 22.7.11.220.449
2izrBRKCasein kinase I isoform gamma-32.7.11.10.449
2q59240Peroxisome proliferator-activated receptor gamma/0.449
2rg5279Mitogen-activated protein kinase 14/0.449
2ym7YM7Serine/threonine-protein kinase Chk12.7.11.10.449
3e8eG98cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.449
3gc7B45Mitogen-activated protein kinase 14/0.449
3mtfA3FActivin receptor type-12.7.11.300.449
4acc7YGGlycogen synthase kinase-3 beta2.7.11.260.449
4ezj0SCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.449
4fto3HKSerine/threonine-protein kinase Chk12.7.11.10.449
4jboWPHAurora kinase A2.7.11.10.449
4u8iFDAUDP-galactopyranose mutase/0.449
5dc5B3NHistone deacetylase 83.5.1.980.449
1k6pXN3Gag-Pol polyprotein3.4.23.160.448
1t0lNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.448
2c3lIDZSerine/threonine-protein kinase Chk12.7.11.10.448
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.448
2gekGDPPhosphatidyl-myo-inositol mannosyltransferase2.4.1.570.448
2henADPEphrin type-B receptor 22.7.10.10.448
2qocANPEphrin type-A receptor 32.7.10.10.448
3cokANPSerine/threonine-protein kinase PLK42.7.11.210.448
4ckiADNProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.448
4kb81QNCasein kinase I isoform delta2.7.11.10.448
4nc3ERM5-hydroxytryptamine receptor 2B/0.448
4tv3ML9Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform/0.448
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.448
5ackATP3-phosphoinositide-dependent protein kinase 12.7.11.10.448
1jld0PPGag-Pol polyprotein/0.447
1jvsNDP1-deoxy-D-xylulose 5-phosphate reductoisomerase1.1.1.2670.447
1xjdSTUProtein kinase C theta type2.7.11.130.447
2p33J07Mitogen-activated protein kinase 102.7.11.240.447
2vzmNRBCytochrome P450 monooxygenase PikC/0.447
2x6dX6DAurora kinase A2.7.11.10.447
3dxjNE6DNA-directed RNA polymerase subunit beta/0.447
3dxjNE6DNA-directed RNA polymerase subunit beta'/0.447
3icsCOACoenzyme A disulfide reductase/0.447
3le62BZCyclin-dependent kinase 22.7.11.220.447
3v3vMYUMitogen-activated protein kinase 82.7.11.240.447
4bgg844Activin receptor type-12.7.11.300.447
4eym0RXMitogen-activated protein kinase 132.7.11.240.447
4ezk0SDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
4ft5H2KSerine/threonine-protein kinase Chk12.7.11.10.447
4lmuQUESerine/threonine-protein kinase pim-12.7.11.10.447
4nky3QZSteroid 17-alpha-hydroxylase/17,20 lyase/0.447
4qmySTUSerine/threonine-protein kinase 242.7.11.10.447
4qnaX11Serine/threonine-protein kinase 242.7.11.10.447
1xkkFMMEpidermal growth factor receptor2.7.10.10.446
2j2iLY4Serine/threonine-protein kinase pim-12.7.11.10.446
2ow3BIMGlycogen synthase kinase-3 beta2.7.11.260.446
2x1nX1NCyclin-dependent kinase 22.7.11.220.446
2ydiYDISerine/threonine-protein kinase Chk12.7.11.10.446
3bgpVX1Serine/threonine-protein kinase pim-12.7.11.10.446
3bheBZNGag-Pol polyprotein3.4.23.160.446
3lfqA28Cyclin-dependent kinase 22.7.11.220.446
3t2zFADSulfide-quinone reductase/0.446
3u4uLNHCasein kinase II subunit alpha2.7.11.10.446
3we45FIRibosomal protein S6 kinase beta-12.7.11.10.446
4acg6LQGlycogen synthase kinase-3 beta2.7.11.260.446
4c61LMMTyrosine-protein kinase JAK2/0.446
4fz70VHTyrosine-protein kinase SYK2.7.10.20.446
5hes032Mitogen-activated protein kinase kinase kinase 202.7.11.250.446
6gswGPSGlutathione S-transferase Mu 12.5.1.180.446
1pkdUCNCyclin-dependent kinase 22.7.11.220.445
1py5PY1TGF-beta receptor type-12.7.11.300.445
2itxANPEpidermal growth factor receptor2.7.10.10.445
2uzlC94Cyclin-dependent kinase 22.7.11.220.445
3cjfSAVVascular endothelial growth factor receptor 22.7.10.10.445
3e5aVX6Aurora kinase A2.7.11.10.445
3iqeF42F420-dependent methylenetetrahydromethanopterin dehydrogenase1.5.98.10.445
3s43478Protease/0.445
3ttiKBIMitogen-activated protein kinase 102.7.11.240.445
4feq0T8Tyrosine-protein kinase receptor TYRO32.7.10.10.445
5f0a1FBcGMP-dependent protein kinase, putative/0.445
1i7iAZ2Peroxisome proliferator-activated receptor gamma/0.444
1rx3MTXDihydrofolate reductase1.5.1.30.444
1t1rIMB1-deoxy-D-xylulose 5-phosphate reductoisomerase1.1.1.2670.444
2chz093Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
2ituITQEpidermal growth factor receptor2.7.10.10.444
2izsBRQCasein kinase I isoform gamma-32.7.11.10.444
2y03Y01Beta-1 adrenergic receptor/0.444
2ycqUPXSerine/threonine-protein kinase Chk22.7.11.10.444
2ydjYDJSerine/threonine-protein kinase Chk12.7.11.10.444
3el8PD5Proto-oncogene tyrosine-protein kinase Src2.7.10.20.444
3gu83GUDeath-associated protein kinase 12.7.11.10.444
4bdgP3JSerine/threonine-protein kinase Chk22.7.11.10.444
4gfg0XFTyrosine-protein kinase SYK2.7.10.20.444
4riyADPEpidermal growth factor receptor2.7.10.10.444
4v010LIFibroblast growth factor receptor 1 (Fms-related tyrosine kinase 2, Pfeiffer syndrome), isoform CRA_b/0.444
5bvw1N1Epithelial discoidin domain-containing receptor 12.7.10.10.444
1bveDMPGag-Pol polyprotein3.4.23.160.443
1di9MSQMitogen-activated protein kinase 14/0.443
1dq8COA3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.340.443
1ebk0Q4Gag-Pol polyprotein3.4.23.160.443
1mqbANPEphrin type-A receptor 22.7.10.10.443
1w5vBE3Gag-Pol polyprotein3.4.23.160.443
2brhDFWSerine/threonine-protein kinase Chk12.7.11.10.443
2qhn582Serine/threonine-protein kinase Chk12.7.11.10.443
2yexYEXSerine/threonine-protein kinase Chk12.7.11.10.443
2yw2ATPPhosphoribosylamine--glycine ligase/0.443
3fl8RARDihydrofolate reductase/0.443
3q92XNBKetohexokinase/0.443
3qaiXNNKetohexokinase/0.443
3u8w09JMitogen-activated protein kinase 14/0.443
4ft0HK9Serine/threonine-protein kinase Chk12.7.11.10.443
4g34924Eukaryotic translation initiation factor 2-alpha kinase 32.7.11.10.443
4xhgADPUncharacterized protein/0.443
5k2dZMAAdenosine receptor A2a/0.443
1jqhANPInsulin-like growth factor 1 receptor2.7.10.10.442
1xr1ANPSerine/threonine-protein kinase pim-12.7.11.10.442
2itvANPEpidermal growth factor receptor2.7.10.10.442
2p4yC03Peroxisome proliferator-activated receptor gamma/0.442
2qfxNDPIsocitrate dehydrogenase [NADP], mitochondrial1.1.1.420.442
2x9fX9FEphrin type-B receptor 42.7.10.10.442
3cblSTUTyrosine-protein kinase Fes/Fps2.7.10.20.442
3rukAERSteroid 17-alpha-hydroxylase/17,20 lyase/0.442
3w18N13Aurora kinase A2.7.11.10.442
3zdiUGJGlycogen synthase kinase-3 beta2.7.11.260.442
3zsi52PMitogen-activated protein kinase 14/0.442
4achKDIGlycogen synthase kinase-3 beta2.7.11.260.442
4aw3MYVMycinamicin IV hydroxylase/epoxidase/0.442
4ewqMWLMitogen-activated protein kinase 14/0.442
4ftaH5KSerine/threonine-protein kinase Chk12.7.11.10.442
4qmwKS1Serine/threonine-protein kinase 242.7.11.10.442
5l8lADPAurora kinase A2.7.11.10.442
1k6cMK1Gag-Pol polyprotein3.4.23.160.441
1kr2TADNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.441
1okySTU3-phosphoinositide-dependent protein kinase 12.7.11.10.441
2hw1ANPKetohexokinase/0.441
2i1m5CNMacrophage colony-stimulating factor 1 receptor2.7.10.10.441
2w4iVGAGlutamate racemase/0.441
2wmqZYQSerine/threonine-protein kinase Chk12.7.11.10.441
2wotZZGTGF-beta receptor type-12.7.11.300.441
2ym44YMSerine/threonine-protein kinase Chk12.7.11.10.441
3cy3JN5Serine/threonine-protein kinase pim-12.7.11.10.441
3dtcVINMitogen-activated protein kinase kinase kinase 92.7.11.250.441
3hvcGG5Mitogen-activated protein kinase 14/0.441
3nunJMZ3-phosphoinositide-dependent protein kinase 12.7.11.10.441
3s54017Protease/0.441
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.441
3w2cN15Aurora kinase A2.7.11.10.441
3zxtACPDeath-associated protein kinase 12.7.11.10.441
4hgs15GCasein kinase I isoform gamma-32.7.11.10.441
4kbk1QGCasein kinase I isoform delta2.7.11.10.441
4qrc0LIFibroblast growth factor receptor 42.7.10.10.441
4u9aSTUInterleukin-1 receptor-associated kinase 42.7.11.10.441
4wuoNAD3-isopropylmalate dehydrogenase1.1.1.850.441
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.441
1chwHXCChalcone synthase 22.3.1.740.440
1ppm0P1Penicillopepsin-13.4.23.200.440
1yi4ADNSerine/threonine-protein kinase pim-12.7.11.10.440
2bikBI1Serine/threonine-protein kinase pim-12.7.11.10.440
2gejGDDPhosphatidyl-myo-inositol mannosyltransferase2.4.1.570.440
2zbaZBATrichothecene 3-O-acetyltransferase/0.440
3ddpRC8Cyclin-dependent kinase 22.7.11.220.440
3et7349Protein-tyrosine kinase 2-beta2.7.10.20.440
3flzFLZMitogen-activated protein kinase 14/0.440
3ogqAB1Pol polyprotein/0.440
4bcnT9NCyclin-dependent kinase 22.7.11.220.440
4c02TAKActivin receptor type-12.7.11.300.440
4g1wG1WMitogen-activated protein kinase 82.7.11.240.440
4gub0Y4Casein kinase II subunit alpha2.7.11.10.440
4h4uNDPBiphenyl dioxygenase ferredoxin reductase subunit/0.440
4looSB4Mitogen-activated protein kinase 14/0.440
5uviZMAAdenosine receptor A2a/0.440
5dhhDGWNociceptin receptor/0.440