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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1yw2PGJMitogen-activated protein kinase 14

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1yw2PGJMitogen-activated protein kinase 14/1.000
3hllI45Mitogen-activated protein kinase 14/0.538
3kf7L9GMitogen-activated protein kinase 14/0.536
1ouk084Mitogen-activated protein kinase 14/0.514
1pmn984Mitogen-activated protein kinase 102.7.11.240.511
4lopSB4Mitogen-activated protein kinase 14/0.510
2p33J07Mitogen-activated protein kinase 102.7.11.240.508
3hl7I47Mitogen-activated protein kinase 14/0.505
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.500
4cd2FOLDihydrofolate reductase1.5.1.30.500
3gc9B45Mitogen-activated protein kinase 112.7.11.240.498
3tqhNDPQuinone oxidoreductase/0.498
2w9sTOPDihydrofolate reductase type 1 from Tn40031.5.1.30.497
3zuyTCHTransporter/0.497
3roc29AMitogen-activated protein kinase 14/0.496
4loqSB4Mitogen-activated protein kinase 14/0.494
1q41IXMGlycogen synthase kinase-3 beta2.7.11.260.489
1m13HYFNuclear receptor subfamily 1 group I member 2/0.488
1bwsNDPGDP-L-fucose synthase/0.487
3ttiKBIMitogen-activated protein kinase 102.7.11.240.487
3t1tGDPProbable gliding protein mglA/0.486
3zuxTCHTransporter/0.486
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.486
1jipKTN6-deoxyerythronolide B hydroxylase/0.485
3bheBZNGag-Pol polyprotein3.4.23.160.485
1k6tXN1Gag-Pol polyprotein3.4.23.160.484
3a1nNADNDP-sugar epimerase/0.484
1jioDEB6-deoxyerythronolide B hydroxylase/0.483
3flkNAITartrate dehydrogenase/decarboxylase1.1.1.930.482
2ghlLIBMitogen-activated protein kinase 14/0.481
5a4kFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.481
3flwFLWMitogen-activated protein kinase 14/0.480
3s1dZIRCytokinin dehydrogenase 11.5.99.120.480
3s4qNK0Mitogen-activated protein kinase 14/0.480
3ttjJBIMitogen-activated protein kinase 102.7.11.240.480
4b7dQLECytochrome P450 monooxygenase PikC/0.480
1d4aFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.479
2d29FADAcyl-CoA dehydrogenase/0.479
2uxoTACHTH-type transcriptional regulator TtgR/0.479
1dhjMTXDihydrofolate reductase1.5.1.30.478
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.478
3kpkFADSulfide-quinone reductase/0.478
3t2kFADSulfide-quinone reductase/0.478
4o59NADGlyceraldehyde-3-phosphate dehydrogenase1.2.1.120.478
1y0s331Peroxisome proliferator-activated receptor delta/0.477
3t2yFADSulfide-quinone reductase/0.477
4eh70OOMitogen-activated protein kinase 14/0.477
5itzLOCTubulin beta-2B chain/0.477
2c6hPXICytochrome P450 monooxygenase PikC/0.476
3vt8YI3Vitamin D3 receptor/0.476
1ddrMTXDihydrofolate reductase1.5.1.30.475
3a99ANPSerine/threonine-protein kinase pim-12.7.11.10.475
3och2MXDihydrofolate reductase1.5.1.30.475
4ylfFADDihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit homolog/0.475
1nvtNAPShikimate dehydrogenase (NADP(+))/0.474
2jn3JN3Fatty acid-binding protein, liver/0.473
2i4zDRHPeroxisome proliferator-activated receptor gamma/0.472
3vt9YI4Vitamin D3 receptor/0.472
3zk5Z18Cytochrome P450 monooxygenase PikC/0.472
4k1b1OCSerine/threonine-protein kinase pim-12.7.11.10.472
1bygSTUTyrosine-protein kinase CSK/0.471
1hdcCBO3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.471
2o2u738Mitogen-activated protein kinase 102.7.11.240.471
2qo9ANPEphrin type-A receptor 32.7.10.10.471
2vzmNRBCytochrome P450 monooxygenase PikC/0.471
3nwxKVSGag-Pol polyprotein3.4.23.160.471
4tuvCPZCytochrome P450 1191.140.471
2i4pDRHPeroxisome proliferator-activated receptor gamma/0.470
4nky3QZSteroid 17-alpha-hydroxylase/17,20 lyase/0.470
1ddsMTXDihydrofolate reductase1.5.1.30.469
3t14FADSulfide-quinone reductase/0.469
1dz6CAMCamphor 5-monooxygenase1.14.15.10.468
3dxjNE6DNA-directed RNA polymerase subunit beta/0.468
3dxjNE6DNA-directed RNA polymerase subunit beta'/0.468
3fi3JK2Mitogen-activated protein kinase 102.7.11.240.468
5dqrFAD7-hydroxymethyl chlorophyll a reductase, chloroplastic1.17.7.20.468
1k6cMK1Gag-Pol polyprotein3.4.23.160.467
2qk8MTXDihydrofolate reductase/0.467
3nwq2NCGag-Pol polyprotein3.4.23.160.467
3uyt0CKCasein kinase I isoform delta2.7.11.10.467
4b7sQLECytochrome P450 monooxygenase PikC/0.467
4h3c0YZDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.467
4looSB4Mitogen-activated protein kinase 14/0.467
4neuQ1AReceptor-interacting serine/threonine-protein kinase 12.7.11.10.467
4r20AERCytochrome P450 family 17 polypeptide 2/0.467
4c58824Cyclin-G-associated kinase2.7.11.10.466
4ryvZEAProtein LlR18A/0.466
1drbMTXDihydrofolate reductase1.5.1.30.465
1ywrLI9Mitogen-activated protein kinase 14/0.465
1zz2B11Mitogen-activated protein kinase 14/0.465
2excJNKMitogen-activated protein kinase 102.7.11.240.465
2izuP01Casein kinase I isoform gamma-32.7.11.10.465
3il1B5DGlutamate receptor 2/0.465
3oafOAGDihydrofolate reductase1.5.1.30.465
4anuEM7Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.465
4hvh19RTyrosine-protein kinase JAK32.7.10.20.464
4nkvAERSteroid 17-alpha-hydroxylase/17,20 lyase/0.464
5e8wSTUTGF-beta receptor type-12.7.11.300.464
1nzdUPGDNA beta-glucosyltransferase/0.463
4k33ACPFibroblast growth factor receptor 32.7.10.10.463
1k6pXN3Gag-Pol polyprotein3.4.23.160.462
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.462
3cgdNADCoenzyme A disulfide reductase/0.462
3ibqATPPyridoxal kinase/0.462
3syiFADSulfide-quinone reductase/0.462
4eutBX7Serine/threonine-protein kinase TBK12.7.11.10.462
4kin1M8Mitogen-activated protein kinase 14/0.462
1e3eNAIAlcohol dehydrogenase 41.1.1.10.461
1gg5FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.461
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.461
2ww4ADP4-diphosphocytidyl-2-C-methyl-D-erythritol kinase2.7.1.1480.461
3begANPSRSF protein kinase 12.7.11.10.461
3h4lANPDNA mismatch repair protein PMS1/0.461
4d0l093Phosphatidylinositol 4-kinase beta2.7.1.670.461
4ifcADPSerine/threonine-protein kinase PRP4 homolog2.7.11.10.461
4q73FADBifunctional protein PutA/0.461
2hmaSAMtRNA-specific 2-thiouridylase MnmA/0.460
2znnS44Peroxisome proliferator-activated receptor alpha/0.460
3bc3OPTCathepsin L13.4.22.150.460
3el4ROCGag-Pol polyprotein3.4.23.160.460
3fklFKLMitogen-activated protein kinase 14/0.460
4a99FADTetX family tetracycline inactivation enzyme/0.460
4kbk1QGCasein kinase I isoform delta2.7.11.10.460
1dxqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.459
1eupASD6-deoxyerythronolide B hydroxylase/0.459
1ia3TQ5Dihydrofolate reductase1.5.1.30.459
3cblSTUTyrosine-protein kinase Fes/Fps2.7.10.20.459
3fwiCAMCamphor 5-monooxygenase1.14.15.10.459
3rukAERSteroid 17-alpha-hydroxylase/17,20 lyase/0.459
3vt7VDXVitamin D3 receptor/0.459
1bvrNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.458
1e8xATPPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.458
1ove358Mitogen-activated protein kinase 14/0.458
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.458
1vjy460TGF-beta receptor type-12.7.11.300.458
1zthADPRIO-type serine/threonine-protein kinase Rio12.7.11.10.458
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.458
3gu83GUDeath-associated protein kinase 12.7.11.10.458
3hwrNDP2-dehydropantoate 2-reductase/0.458
3mdvCL6Cholesterol 24-hydroxylase/0.458
3th8TH9Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.458
3w2sW2REpidermal growth factor receptor2.7.10.10.458
4biiPYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.458
4c59FEFCyclin-G-associated kinase2.7.11.10.458
4j95ACPFibroblast growth factor receptor 2/0.458
1kboFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.457
1zrzBI1Protein kinase C iota type2.7.11.130.457
2ca0PXICytochrome P450 monooxygenase PikC/0.457
2zdt46CMitogen-activated protein kinase 102.7.11.240.457
3el51UNGag-Pol polyprotein/0.457
3fln3FNMitogen-activated protein kinase 14/0.457
3iw5DF3Mitogen-activated protein kinase 14/0.457
3slkNDPPolyketide synthase extender module 2/0.457
4aotGW8Serine/threonine-protein kinase 102.7.11.10.457
4o701QKBromodomain-containing protein 4/0.457
1dyjDDFDihydrofolate reductase1.5.1.30.456
1kc1NDPdTDP-4-dehydrorhamnose reductase1.1.1.1330.456
1re7FOLDihydrofolate reductase1.5.1.30.456
2f1kNAPPrephenate dehydrogenase/0.456
3f03FMNPentaerythritol tetranitrate reductase/0.456
3sgx0FWDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.456
4cztCPSCBL-interacting serine/threonine-protein kinase 232.7.11.10.456
4hbm0Y7E3 ubiquitin-protein ligase Mdm26.3.20.456
4jvf17XRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.456
4nfn2KCTau-tubulin kinase 12.7.11.10.456
4o4fATPKinase/0.456
5hi6MTXDihydrofolate reductase/0.456
1m2pHNACasein kinase II subunit alpha2.7.11.10.455
1tw4CHDFatty acid-binding protein, liver/0.455
3atzFMNProstaglandin F2a synthase/0.455
3iw6PP0Mitogen-activated protein kinase 14/0.455
3l0lHC3Nuclear receptor ROR-gamma/0.455
3mvl38PMitogen-activated protein kinase 14/0.455
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.455
3sz0FADSulfide-quinone reductase/0.455
4a33MYAGlycylpeptide N-tetradecanoyltransferase/0.455
4a6cQG9Gag-Pol polyprotein3.4.23.160.455
4eh60ONMitogen-activated protein kinase 14/0.455
4ewqMWLMitogen-activated protein kinase 14/0.455
4i3wNADAldehyde dehydrogenase (NAD+)/0.455
4jib1L6cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.455
5a9sNAPPutative dehydrogenase/0.455
1zmdNAIDihydrolipoyl dehydrogenase, mitochondrial1.8.1.40.454
2drcMTXDihydrofolate reductase1.5.1.30.454
2ft9CHDFatty acid-binding protein 2, liver/0.454
3fc152PMitogen-activated protein kinase 14/0.454
3mdmFJZCholesterol 24-hydroxylase/0.454
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.454
3zh8C58Protein kinase C iota type2.7.11.130.454
3zsi52PMitogen-activated protein kinase 14/0.454
4aa5NQBMitogen-activated protein kinase 14/0.454
4aacAAVMitogen-activated protein kinase 14/0.454
4bgePYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.454
4dfrMTXDihydrofolate reductase1.5.1.30.454
1dirNADDihydropteridine reductase1.5.1.340.453
1h66FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.453
1sduMK1Gag-Pol polyprotein3.4.23.160.453
1zeoC01Peroxisome proliferator-activated receptor gamma/0.453
2cy0NAPShikimate dehydrogenase (NADP(+))/0.453
3f69XDRSerine/threonine-protein kinase PknB2.7.11.10.453
3mtfA3FActivin receptor type-12.7.11.300.453
3nxe2NCProtease/0.453
3poz03PEpidermal growth factor receptor2.7.10.10.453
4kb81QOCasein kinase I isoform delta2.7.11.10.453
5eypLOCTubulin beta chain/0.453
1draMTXDihydrofolate reductase1.5.1.30.452
1hiiC20Gag-Pol polyprotein/0.452
1xl2189Gag-Pol polyprotein3.4.23.160.452
1xr1ANPSerine/threonine-protein kinase pim-12.7.11.10.452
2ghmLICMitogen-activated protein kinase 14/0.452
2xgoZKDUncharacterized protein/0.452
3mpaSB2Mitogen-activated protein kinase 14/0.452
3zep1NXTyrosine-protein kinase JAK32.7.10.20.452
3zsh469Mitogen-activated protein kinase 14/0.452
4k110J9Proto-oncogene tyrosine-protein kinase Src2.7.10.20.452
4nka2K7Fibroblast growth factor receptor 1/0.452
4r21STRCytochrome P450 family 17 polypeptide 2/0.452
1dxoFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.451
1zhzERGOxysterol-binding protein homolog 4/0.451
2ckeIQUDeath-associated protein kinase 2/0.451
2r3wG3GGag-Pol polyprotein3.4.23.160.451
3d8bADPFidgetin-like protein 13.6.40.451
3eteNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.451
3fl9TOPDihydrofolate reductase/0.451
3g49NAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.451
3gobHXXDdmC/0.451
3vtdTKDVitamin D3 receptor/0.451
4anv751Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.451
4bgiI4IEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.451
4bibIEOMitogen-activated protein kinase kinase kinase 52.7.11.250.451
4dtiNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.451
4elb34RDihydrofolate reductase/0.451
4f640S8Fibroblast growth factor receptor 1/0.451
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.451
4oaeCLMUncharacterized protein/0.451
4xiwAZMCarbonic anhydrase, alpha type/0.451
1dhfFOLDihydrofolate reductase1.5.1.30.450
1h69FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.450
1hwzNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.450
1lldNADL-lactate dehydrogenase 21.1.1.270.450
1siqFADGlutaryl-CoA dehydrogenase, mitochondrial1.3.8.60.450
1v9aSAHUncharacterized protein/0.450
1y57MPZProto-oncogene tyrosine-protein kinase Src2.7.10.20.450
1zmcNADDihydrolipoyl dehydrogenase, mitochondrial1.8.1.40.450
2balPQAMitogen-activated protein kinase 14/0.450
2ovhAS0Progesterone receptor/0.450
2z97CAMCamphor 5-monooxygenase1.14.15.10.450
4g3rCAMCamphor 5-monooxygenase1.14.15.10.450
4j97ACPFibroblast growth factor receptor 2/0.450
4jia1K3Tyrosine-protein kinase JAK2/0.450
4o0rX4ZSerine/threonine-protein kinase PAK 12.7.11.10.450
5cshATPCasein kinase II subunit alpha2.7.11.10.450
1iyzNDPProbable quinone oxidoreductase/0.449
1m7qDQOMitogen-activated protein kinase 14/0.449
1ml3NADGlyceraldehyde-3-phosphate dehydrogenase, glycosomal1.2.1.120.449
1ouy094Mitogen-activated protein kinase 14/0.449
1qxsNADGlyceraldehyde-3-phosphate dehydrogenase, glycosomal1.2.1.120.449
1rb3MTXDihydrofolate reductase1.5.1.30.449
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.449
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.449
2iebZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.449
2nnhREACytochrome P450 2C8/0.449
2om9AJAPeroxisome proliferator-activated receptor gamma/0.449
2qd9LGFMitogen-activated protein kinase 14/0.449
2qnqQN3Gag-Pol polyprotein3.4.23.160.449
3fmkFMKMitogen-activated protein kinase 14/0.449
3hvcGG5Mitogen-activated protein kinase 14/0.449
3p74FMNPentaerythritol tetranitrate reductase/0.449
3tucFPWTyrosine-protein kinase SYK2.7.10.20.449
4jx1CAMCamphor 5-monooxygenase1.14.15.10.449
4ocvANPAminoglycoside phosphotransferase/0.449
4v2gITCTetracycline repressor protein class D/0.449
4x5jFOLDihydrofolate reductase1.5.1.30.449
1jolFFODihydrofolate reductase1.5.1.30.448
1lsoNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.448
2fr0NDP6-deoxyerythronolide-B synthase EryA1, modules 1 and 2/0.448
2wyvNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.448
3b895GP16S rRNA methylase/0.448
3cv9VDXVitamin D3 dihydroxylase/0.448
4a6bQG8Gag-Pol polyprotein3.4.23.160.448
4bidIE8Mitogen-activated protein kinase kinase kinase 52.7.11.250.448
4enhFVXCholesterol 24-hydroxylase/0.448
4hfmNAP2-alkenal reductase (NADP(+)-dependent)/0.448
4nbwNADShort-chain dehydrogenase/reductase SDR/0.448
1dhiMTXDihydrofolate reductase1.5.1.30.447
1e7qNAPGDP-L-fucose synthase/0.447
1g2vTTPGlucose-1-phosphate thymidylyltransferase/0.447
1hvlA76Gag-Pol polyprotein/0.447
1qnfFADDeoxyribodipyrimidine photo-lyase4.1.99.30.447
1yrdCAMCamphor 5-monooxygenase1.14.15.10.447
2dvlFADAcyl-CoA dehydrogenase/0.447
2f4bEHAPeroxisome proliferator-activated receptor gamma/0.447
3el01UNGag-Pol polyprotein3.4.23.160.447
3igoANPCalmodulin-domain protein kinase 1, putative/0.447
3lj3WYEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
3t2zFADSulfide-quinone reductase/0.447
3umoATPATP-dependent 6-phosphofructokinase isozyme 22.7.1.110.447
4elb34SDihydrofolate reductase/0.447
4h9814QUncharacterized protein/0.447
4lxhC1EAlpha/beta hydrolase fold/0.447
4qmxH8HSerine/threonine-protein kinase 242.7.11.10.447
1gufNDPEnoyl-[acyl-carrier-protein] reductase 1, mitochondrial1.3.1.100.446
1iwjCAMCamphor 5-monooxygenase1.14.15.10.446
1yonA2R2-dehydropantoate 2-reductase1.1.1.1690.446
1zyjBI5Mitogen-activated protein kinase 14/0.446
2a1nCAMCamphor 5-monooxygenase1.14.15.10.446
2aqkNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.446
2gtmLIDMitogen-activated protein kinase 14/0.446
2lbaCHOFatty acid binding protein 6/0.446
2yylFAD4-hydroxyphenylacetate 3-monooxygenase oxygenase component1.14.14.90.446
2zbaZBATrichothecene 3-O-acetyltransferase/0.446
3bva2NCGag-Pol polyprotein3.4.23.160.446
3gstGPRGlutathione S-transferase Mu 12.5.1.180.446
3gw9VNILanosterol 14-alpha-demethylase/0.446
3gxlQIGTGF-beta receptor type-12.7.11.300.446
3kytHC2Nuclear receptor ROR-gamma/0.446
3lshFADPyranose 2-oxidase/0.446
3s56ROCProtease/0.446
3tea4CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.446
4fuyEK2Mitogen-activated protein kinase 12.7.11.240.446
4gk2L66Ephrin type-A receptor 32.7.10.10.446
4i22IREEpidermal growth factor receptor2.7.10.10.446
4nk92K5Fibroblast growth factor receptor 1/0.446
4xwtU5PRibonuclease J/0.446
4zseANPEpidermal growth factor receptor2.7.10.10.446
1bsvNDPGDP-L-fucose synthase/0.445
1jld0PPGag-Pol polyprotein/0.445
1s3zCOAAminoglycoside N(6')-acetyltransferase type 1/0.445
1y4lSVRBasic phospholipase A2 homolog 2/0.445
1zhwHC2Oxysterol-binding protein homolog 4/0.445
2bpw1INGag-Pol polyprotein3.4.23.160.445
2hw2RFPRifampin ADP-ribosyl transferase/0.445
2pziAXXSerine/threonine-protein kinase PknG2.7.11.10.445
2qfxNDPIsocitrate dehydrogenase [NADP], mitochondrial1.1.1.420.445
2rioADPSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.445
3cjgKIMVascular endothelial growth factor receptor 22.7.10.10.445
3fl8RARDihydrofolate reductase/0.445
3o9cK20Pol polyprotein/0.445
3uvp048Mitogen-activated protein kinase 14/0.445
4g3jVNTLanosterol 14-alpha-demethylase/0.445
4hvi19STyrosine-protein kinase JAK32.7.10.20.445
4ix6ADPUncharacterized protein/0.445
4nb6444Nuclear receptor ROR-gamma/0.445
4yr9NADL-threonine 3-dehydrogenase, mitochondrial1.1.1.1030.445
5bmvVLBTubulin alpha-1B chain/0.445
5bmvVLBTubulin beta chain/0.445
1bw9NADPhenylalanine dehydrogenase/0.444
1f4gTP4Thymidylate synthase/0.444
1n83CLRNuclear receptor ROR-alpha/0.444
1rv1IMZE3 ubiquitin-protein ligase Mdm26.3.20.444
1s60COAAminoglycoside N(6')-acetyltransferase type 1/0.444
1xuoLA1Integrin alpha-L/0.444
1zp9ATPRIO-type serine/threonine-protein kinase Rio12.7.11.10.444
2ejvNADL-threonine 3-dehydrogenase/0.444
2q7vFADThioredoxin reductase/0.444
2uzwSS4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.444
3cgoJNOMitogen-activated protein kinase 102.7.11.240.444
3ckxSTUSerine/threonine-protein kinase 242.7.11.10.444
3ggu017Gag-Pol polyprotein3.4.23.160.444
3h8bNSYCathepsin L13.4.22.150.444
3k4vROCGag-Pol polyprotein3.4.23.160.444
3mg3ECHOrange carotenoid-binding protein/0.444
3r7iX9ICyclin-dependent kinase 22.7.11.220.444
3zptM8YGag-Pol polyprotein3.4.23.160.444
4c7kNAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.444
4e5yNDPGDP-L-fucose synthase1.1.1.2710.444
4idv13VMitogen-activated protein kinase kinase kinase 142.7.11.250.444
4lsmNADGlyceraldehyde-3-phosphate dehydrogenase/0.444
4rnuFMNNADPH dehydrogenase 11.6.99.10.444
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.443
1wntNAPL-xylulose reductase1.1.1.100.443
2uzvSS5cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.443
2wpxACOOrf14/0.443
3c7qXINVascular endothelial growth factor receptor 22.7.10.10.443
3d8vUD1Bifunctional protein GlmU/0.443
3e8eG98cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.443
3eek53SUncharacterized protein/0.443
3flyFLYMitogen-activated protein kinase 14/0.443
3frqERYErythromycin resistance repressor protein/0.443
3hk1B64Fatty acid-binding protein, adipocyte/0.443
3icrFADCoenzyme A disulfide reductase/0.443
3k5uPFQAurora kinase A2.7.11.10.443
3pe6ZYHMonoglyceride lipase/0.443
3so9017Pol protein/0.443
4aa4QC0Mitogen-activated protein kinase 14/0.443
4ewn0VRImidazole glycerol phosphate synthase subunit HisF4.1.30.443
4ful0VUPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
4gmy0X5Tyrosine-protein kinase JAK2/0.443
4l9kEHFSerum albumin/0.443
4nieNBHNuclear receptor ROR-gamma/0.443
4pl3ADPSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.443
1ivp1ZKGag-Pol polyprotein/0.442
1kkq471Peroxisome proliferator-activated receptor alpha/0.442
1owmFADDeoxyribodipyrimidine photo-lyase4.1.99.30.442
2i3gNAPN-acetyl-gamma-glutamyl-phosphate reductase1.2.1.380.442
2nnkROCProtease/0.442
2qocANPEphrin type-A receptor 32.7.10.10.442
2vn0TDZCytochrome P450 2C8/0.442
3a1l2CCCytochrome P450/0.442
3cktYDPGag-Pol polyprotein3.4.23.160.442
3e5rNADGlyceraldehyde-3-phosphate dehydrogenase 1, cytosolic1.2.1.120.442
3p62FMNPentaerythritol tetranitrate reductase/0.442
3p8jFMNPentaerythritol tetranitrate reductase/0.442
3qp0NI8Gag-Pol polyprotein3.4.23.160.442
3w1tWRODihydroorotate dehydrogenase (fumarate)1.3.98.10.442
4jbqVX6Aurora kinase A2.7.11.10.442
5dt3ATPAurora kinase A2.7.11.10.442
1c70L75Protease/0.441
1eh4IC1Casein kinase I homolog 12.7.11.10.441
1o0sNAINAD-dependent malic enzyme, mitochondrial1.1.1.380.441
1zidZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.441
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.441
2idw017Protease/0.441
2itzIREEpidermal growth factor receptor2.7.10.10.441
2oh02PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.441
2y1oT26UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.441
2zjwREFCasein kinase II subunit alpha2.7.11.10.441
3fi4FI4Mitogen-activated protein kinase 14/0.441
3ggxGGXGag-Pol polyprotein/0.441
3icsCOACoenzyme A disulfide reductase/0.441
3ictCOACoenzyme A disulfide reductase/0.441
3ma301ISerine/threonine-protein kinase pim-12.7.11.10.441
3of2NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.441
3oom507Activin receptor type-12.7.11.300.441
3r34COA4-hydroxybenzoyl-CoA thioesterase3.1.2.230.441
3s79ASDAromatase1.14.14.140.441
4e2bFMNDehydrogenase/0.441
4hdbG52Gag-Pol polyprotein3.4.23.160.441
4njvRITProtease/0.441
1cqp803Integrin alpha-L/0.440
1difA85Gag-Pol polyprotein/0.440
1g35AHFGag-Pol polyprotein3.4.23.160.440
1phgMYTCamphor 5-monooxygenase1.14.15.10.440
1t88CAMCamphor 5-monooxygenase1.14.15.10.440
2bxoOPBSerum albumin/0.440
2ftoCB3Thymidylate synthase/0.440
3dheANDEstradiol 17-beta-dehydrogenase 11.1.1.620.440
3f5p741Insulin-like growth factor 1 receptor2.7.10.10.440
3fmh533Mitogen-activated protein kinase 14/0.440
3fwgCAMCamphor 5-monooxygenase1.14.15.10.440
3hp552PMitogen-activated protein kinase 14/0.440
3mvqNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.440
3ndrNADPyridoxal 4-dehydrogenase1.1.1.1070.440
3nyg2NCGag-Pol polyprotein3.4.23.160.440
3pwrROCGag-Pol polyprotein3.4.23.160.440
3rudNADUDP-N-acetylglucosamine 4-epimerase/0.440
3ssnMVIMycinamicin VI 2''-O-methyltransferase/0.440
3wrlCAMCamphor 5-monooxygenase1.14.15.10.440
4at0FADPossible succinate dehydrogenase/0.440
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.440