sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1ihx | SND | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1ihx | SND | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 1.000 | |
| 3ids | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.639 | |
| 1u8f | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.621 | |
| 1szj | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.615 | |
| 4o63 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.615 | |
| 1dbv | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.613 | |
| 1hdg | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.603 | |
| 3v1y | NAD | Glyceraldehyde-3-phosphate dehydrogenase 1, cytosolic | 1.2.1.12 | 0.599 | |
| 1rm5 | NDP | Glyceraldehyde-3-phosphate dehydrogenase A, chloroplastic | 1.2.1.13 | 0.596 | |
| 3gnq | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.596 | |
| 2dbv | NDP | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.594 | |
| 4lsm | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.592 | |
| 4dbv | NDP | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.589 | |
| 1npt | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.587 | |
| 1ml3 | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.582 | |
| 4p8r | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.582 | |
| 4boy | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.581 | |
| 1rm4 | NDP | Glyceraldehyde-3-phosphate dehydrogenase A, chloroplastic | 1.2.1.13 | 0.580 | |
| 1a7k | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.572 | |
| 4z0h | NAD | Glyceraldehyde-3-phosphate dehydrogenase GAPC1, cytosolic | 1.2.1.12 | 0.571 | |
| 3ksd | NAD | Glyceraldehyde-3-phosphate dehydrogenase 1 | / | 0.569 | |
| 2b4r | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.565 | |
| 5c7o | NAD | Glyceraldehyde-3-phosphate dehydrogenase, testis-specific | 1.2.1.12 | 0.564 | |
| 1jn0 | NDP | Glyceraldehyde-3-phosphate dehydrogenase A, chloroplastic | 1.2.1.13 | 0.563 | |
| 3cps | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.563 | |
| 1dc6 | NAD | Glyceraldehyde-3-phosphate dehydrogenase A | / | 0.560 | |
| 1vsv | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.558 | |
| 1gad | NAD | Glyceraldehyde-3-phosphate dehydrogenase A | / | 0.555 | |
| 2d2i | NAP | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.552 | |
| 3doc | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.552 | |
| 3l4s | NAD | Glyceraldehyde-3-phosphate dehydrogenase 1 | / | 0.552 | |
| 3cmc | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.551 | |
| 1ywg | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.548 | |
| 1rm3 | NDP | Glyceraldehyde-3-phosphate dehydrogenase A, chloroplastic | 1.2.1.13 | 0.547 | |
| 3k2b | NAD | Glyceraldehyde-3-phosphate dehydrogenase GAPA1, chloroplastic | 1.2.1.13 | 0.547 | |
| 1nbo | NAD | Glyceraldehyde-3-phosphate dehydrogenase A, chloroplastic | 1.2.1.13 | 0.546 | |
| 3pym | NAD | Glyceraldehyde-3-phosphate dehydrogenase 3 | 1.2.1.12 | 0.545 | |
| 2ep7 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.543 | |
| 3zcx | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.538 | |
| 3l0d | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.536 | |
| 1ihy | APR | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.534 | |
| 3dbv | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.533 | |
| 1j0x | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.529 | |
| 1gae | NAD | Glyceraldehyde-3-phosphate dehydrogenase A | / | 0.523 | |
| 1vc2 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.510 | |
| 1pdh | FAS | p-hydroxybenzoate hydroxylase | / | 0.499 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.498 | |
| 4iwo | 1H4 | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.498 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.490 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.487 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.486 | |
| 3umv | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.486 | |
| 4nmd | FDA | Bifunctional protein PutA | / | 0.483 | |
| 4xgx | ADP | FAD:protein FMN transferase | / | 0.483 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.480 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.480 | |
| 2jcx | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.480 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.480 | |
| 3zuy | TCH | Transporter | / | 0.480 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.478 | |
| 1dhi | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.478 | |
| 2brm | DFZ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.477 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.476 | |
| 2chx | 090 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.474 | |
| 4nxv | GDP | Mitochondrial dynamics protein MID51 | / | 0.473 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.472 | |
| 1l8q | ADP | Chromosomal replication initiator protein DnaA | / | 0.472 | |
| 2xvi | FAD | Putative flavin-containing monooxygenase | / | 0.472 | |
| 4ips | 1G4 | Mycocyclosin synthase | 1.14.21.9 | 0.470 | |
| 1tez | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.469 | |
| 2cvu | CDP | Ribonucleoside-diphosphate reductase large chain 1 | 1.17.4.1 | 0.469 | |
| 3r04 | UNQ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.469 | |
| 4nxu | ADP | Mitochondrial dynamics protein MID51 | / | 0.469 | |
| 2wot | ZZG | TGF-beta receptor type-1 | 2.7.11.30 | 0.468 | |
| 4gyz | D5M | Tyrosyl-DNA phosphodiesterase 2 | 3.1.4 | 0.468 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.468 | |
| 3gob | HXX | DdmC | / | 0.467 | |
| 4eut | BX7 | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.467 | |
| 4f4d | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.467 | |
| 4l9k | EHF | Serum albumin | / | 0.467 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.466 | |
| 3rud | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.466 | |
| 4kzo | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.466 | |
| 5eio | NAP | [LysW]-L-2-aminoadipate 6-phosphate reductase | / | 0.466 | |
| 1byg | STU | Tyrosine-protein kinase CSK | / | 0.465 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.465 | |
| 3zux | TCH | Transporter | / | 0.465 | |
| 4gk2 | L66 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.465 | |
| 4ia1 | BIV | Vitamin D3 receptor A | / | 0.465 | |
| 4nxw | ADP | Mitochondrial dynamics protein MID51 | / | 0.465 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.464 | |
| 1gzu | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.463 | |
| 1tl7 | FOK | Adenylate cyclase type 2 | / | 0.463 | |
| 1tl7 | FOK | Adenylate cyclase type 5 | / | 0.463 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.463 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.463 | |
| 3nd1 | SAH | Precorrin-6A synthase (Deacetylating) | / | 0.463 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.463 | |
| 2cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.462 | |
| 3r6s | CMP | CRP-like cAMP-activated global transcriptional regulator | / | 0.462 | |
| 3s8c | CDP | Ribonucleoside-diphosphate reductase large chain 1 | 1.17.4.1 | 0.462 | |
| 3u8w | 09J | Mitogen-activated protein kinase 14 | / | 0.462 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.462 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.461 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.461 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.461 | |
| 3sdk | P3N | Proteasome subunit beta type-5 | 3.4.25.1 | 0.461 | |
| 3sdk | P3N | Proteasome subunit beta type-6 | 3.4.25.1 | 0.461 | |
| 4aos | NAP | Steroid monooxygenase | / | 0.461 | |
| 4e5y | NDP | GDP-L-fucose synthase | 1.1.1.271 | 0.461 | |
| 4ge7 | 0K5 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.461 | |
| 5dqr | FAD | 7-hydroxymethyl chlorophyll a reductase, chloroplastic | 1.17.7.2 | 0.461 | |
| 1d7l | RFL | p-hydroxybenzoate hydroxylase | / | 0.460 | |
| 4hle | 17V | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.460 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.460 | |
| 4iwq | 1FV | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.460 | |
| 4z64 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.460 | |
| 5bsf | NAD | Pyrroline-5-carboxylate reductase | / | 0.460 | |
| 2eq7 | NAD | Dihydrolipoyl dehydrogenase | / | 0.459 | |
| 3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.459 | |
| 3of2 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.459 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 1jm6 | ADP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial | 2.7.11.2 | 0.458 | |
| 1tqf | 32P | Beta-secretase 1 | 3.4.23.46 | 0.458 | |
| 2y3r | TIR | TamL | / | 0.458 | |
| 3mtf | A3F | Activin receptor type-1 | 2.7.11.30 | 0.458 | |
| 3nwx | KVS | Gag-Pol polyprotein | 3.4.23.16 | 0.458 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 3u9e | COA | Lmo1369 protein | / | 0.458 | |
| 1g4t | FTP | Thiamine-phosphate synthase | / | 0.457 | |
| 1jio | DEB | 6-deoxyerythronolide B hydroxylase | / | 0.457 | |
| 2g37 | FAD | Proline dehydrogenase | / | 0.457 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.457 | |
| 2x0r | NAD | Malate dehydrogenase | / | 0.457 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.457 | |
| 4cuk | NAI | D-lactate dehydrogenase | / | 0.457 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.457 | |
| 1cjt | FOK | Adenylate cyclase type 2 | / | 0.456 | |
| 1cjt | FOK | Adenylate cyclase type 5 | / | 0.456 | |
| 1owm | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.456 | |
| 1yjq | NAP | 2-dehydropantoate 2-reductase | 1.1.1.169 | 0.456 | |
| 2p33 | J07 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.456 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.456 | |
| 2xh9 | J01 | Uncharacterized protein | / | 0.456 | |
| 3nr4 | PYV | Abscisic acid receptor PYL2 | / | 0.456 | |
| 3zc3 | NAP | Ferredoxin--NADP reductase | 1.18.1.2 | 0.456 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.456 | |
| 4jbi | NDP | Alcohol dehydrogenase (Zinc) | / | 0.456 | |
| 6cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.456 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.455 | |
| 2pwc | G3G | Gag-Pol polyprotein | 3.4.23.16 | 0.455 | |
| 2rkv | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.455 | |
| 2v7a | 627 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.455 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 3ns2 | PYV | Abscisic acid receptor PYL2 | / | 0.455 | |
| 3otq | MZL | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.455 | |
| 4j33 | FAD | Kynurenine 3-monooxygenase | / | 0.455 | |
| 1dhj | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 1dz6 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.454 | |
| 1eup | ASD | 6-deoxyerythronolide B hydroxylase | / | 0.454 | |
| 1ia1 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 2nru | T12 | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.454 | |
| 2qbo | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.454 | |
| 2yyi | FAD | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component | 1.14.14.9 | 0.454 | |
| 3slk | NDP | Polyketide synthase extender module 2 | / | 0.454 | |
| 3wbb | NAP | Meso-diaminopimelate D-dehydrogenase | / | 0.454 | |
| 4uym | VOR | 14-alpha sterol demethylase Cyp51B | / | 0.454 | |
| 4xb2 | NDP | 319aa long hypothetical homoserine dehydrogenase | / | 0.454 | |
| 5eai | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.454 | |
| 1e90 | MYC | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.453 | |
| 1uu9 | BI3 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.453 | |
| 2i4z | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.453 | |
| 4rbs | 0RV | Metallo-beta-lactamase type 2 | / | 0.453 | |
| 4tqg | NDP | Putative dTDP-d-glucose 4 6-dehydratase | / | 0.453 | |
| 1dhr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.452 | |
| 2jcv | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.452 | |
| 2y3r | TRK | TamL | / | 0.452 | |
| 3fwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 3tjs | D0R | Cytochrome P450 3A4 | / | 0.452 | |
| 4a6b | QG8 | Gag-Pol polyprotein | 3.4.23.16 | 0.452 | |
| 4c3f | 7KW | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.452 | |
| 1bw9 | NAD | Phenylalanine dehydrogenase | / | 0.451 | |
| 1dnp | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.451 | |
| 1dxo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.451 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.451 | |
| 1v9a | SAH | Uncharacterized protein | / | 0.451 | |
| 2a1n | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 2iyf | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.451 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.451 | |
| 2npn | SAM | Putative cobalamin synthesis related protein | / | 0.451 | |
| 2uxp | CLM | HTH-type transcriptional regulator TtgR | / | 0.451 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 2ww4 | ADP | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | 2.7.1.148 | 0.451 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 3g5h | YTT | Mycocyclosin synthase | 1.14.21.9 | 0.451 | |
| 3ics | ADP | Coenzyme A disulfide reductase | / | 0.451 | |
| 3s79 | ASD | Aromatase | 1.14.14.14 | 0.451 | |
| 4cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 4dre | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.451 | |
| 4j2w | FAD | Kynurenine 3-monooxygenase | / | 0.451 | |
| 4kwi | 1TJ | Reductase homolog | / | 0.451 | |
| 4n6h | EJ4 | Delta-type opioid receptor | / | 0.451 | |
| 1eio | GCH | Gastrotropin | / | 0.450 | |
| 1k6c | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.450 | |
| 1k7l | 544 | Peroxisome proliferator-activated receptor alpha | / | 0.450 | |
| 1qnf | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.450 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.450 | |
| 3a99 | ANP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.450 | |
| 3frq | ERY | Erythromycin resistance repressor protein | / | 0.450 | |
| 3k6l | 2BB | Peptide deformylase | 3.5.1.88 | 0.450 | |
| 3qd3 | 3Q5 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.450 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.450 | |
| 3say | OFT | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.450 | |
| 3zh8 | C58 | Protein kinase C iota type | 2.7.11.13 | 0.450 | |
| 4h8n | NDP | NADPH-dependent conjugated polyketone reductase C2 | / | 0.450 | |
| 4i02 | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.450 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.450 | |
| 4xf7 | ACP | Carbohydrate/pyrimidine kinase, PfkB family | / | 0.450 | |
| 4xj4 | 3AT | Cyclic GMP-AMP synthase | / | 0.450 | |
| 1dyi | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1k6t | XN1 | Gag-Pol polyprotein | 3.4.23.16 | 0.449 | |
| 2ktd | PUC | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.449 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.449 | |
| 2zax | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 3il1 | B5D | Glutamate receptor 2 | / | 0.449 | |
| 3nxe | 2NC | Protease | / | 0.449 | |
| 3p99 | LNP | Lanosterol 14-alpha-demethylase | / | 0.449 | |
| 3wrj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 4c57 | FEF | Cyclin-G-associated kinase | 2.7.11.1 | 0.449 | |
| 4f9f | GDP | Putative glycosyltransferase | / | 0.449 | |
| 4gk3 | L87 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.449 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.449 | |
| 5d3q | GDP | Dynamin-1 | 3.6.5.5 | 0.449 | |
| 1gjv | AGS | [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial | 2.7.11.4 | 0.448 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.448 | |
| 2bal | PQA | Mitogen-activated protein kinase 14 | / | 0.448 | |
| 2vn0 | TDZ | Cytochrome P450 2C8 | / | 0.448 | |
| 2vx1 | 7X8 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.448 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.448 | |
| 3kf7 | L9G | Mitogen-activated protein kinase 14 | / | 0.448 | |
| 3nwq | 2NC | Gag-Pol polyprotein | 3.4.23.16 | 0.448 | |
| 3ras | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.448 | |
| 4yao | FMN | NADPH--cytochrome P450 reductase | / | 0.448 | |
| 4ysw | FAD | Xanthine dehydrogenase/oxidase | / | 0.448 | |
| 1t88 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 2y8q | ADP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.447 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.447 | |
| 3had | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.447 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.447 | |
| 3mqe | 416 | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.447 | |
| 3qf9 | NM8 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.447 | |
| 4gxs | 0YS | Glutamate receptor 2 | / | 0.447 | |
| 4l6g | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.447 | |
| 4yr9 | NAD | L-threonine 3-dehydrogenase, mitochondrial | 1.1.1.103 | 0.447 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.446 | |
| 1k6v | XN2 | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 1o76 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 1u4d | DBQ | Activated CDC42 kinase 1 | / | 0.446 | |
| 2brb | PFQ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.446 | |
| 2i4p | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.446 | |
| 2q46 | NAP | Uncharacterized protein At5g02240 | / | 0.446 | |
| 3a1n | NAD | NDP-sugar epimerase | / | 0.446 | |
| 3oev | 3OE | Proteasome subunit beta type-5 | 3.4.25.1 | 0.446 | |
| 3oev | 3OE | Proteasome subunit beta type-6 | 3.4.25.1 | 0.446 | |
| 3qj5 | 022 | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.446 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.446 | |
| 4dqu | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.446 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.446 | |
| 4h3c | 0YZ | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.446 | |
| 4i6a | HMG | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.88 | 0.446 | |
| 4nmb | FAD | Bifunctional protein PutA | / | 0.446 | |
| 4y1b | NAP | AntE | / | 0.446 | |
| 1iwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 1mj9 | COA | Histone acetyltransferase ESA1 | / | 0.445 | |
| 1t85 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 2itq | ITQ | Epidermal growth factor receptor | 2.7.10.1 | 0.445 | |
| 2vwx | 7X4 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.445 | |
| 2x0i | NAI | Malate dehydrogenase | / | 0.445 | |
| 2zkj | ADP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial | 2.7.11.2 | 0.445 | |
| 3a14 | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.445 | |
| 3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 3rue | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.445 | |
| 3vqs | JT1 | Genome polyprotein | / | 0.445 | |
| 4bqp | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.445 | |
| 4fmx | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.445 | |
| 4l4c | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 4qmx | H8H | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.445 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.444 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 2jds | L20 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.444 | |
| 2w0b | CMW | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.444 | |
| 3cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.444 | |
| 3ofm | 4B0 | Casein kinase II subunit alpha' | 2.7.11.1 | 0.444 | |
| 3p7n | FMN | Light-activated DNA-binding protein EL222 | / | 0.444 | |
| 4z63 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.444 | |
| 1cjv | FOK | Adenylate cyclase type 2 | / | 0.443 | |
| 1cjv | FOK | Adenylate cyclase type 5 | / | 0.443 | |
| 1drb | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1lbc | CYZ | Glutamate receptor 2 | / | 0.443 | |
| 1lso | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.443 | |
| 1nuq | NXX | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.443 | |
| 1u3c | FAD | Cryptochrome-1 | / | 0.443 | |
| 1uyu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 2bdf | 24A | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.443 | |
| 2dfv | NAD | L-threonine 3-dehydrogenase | / | 0.443 | |
| 2xhd | 7T9 | Glutamate receptor 2 | / | 0.443 | |
| 3a4o | STU | Tyrosine-protein kinase Lyn | 2.7.10.2 | 0.443 | |
| 3c0g | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.443 | |
| 3c15 | FOK | Adenylate cyclase type 2 | / | 0.443 | |
| 3c15 | FOK | Adenylate cyclase type 5 | / | 0.443 | |
| 3flw | FLW | Mitogen-activated protein kinase 14 | / | 0.443 | |
| 3fwg | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 3gxo | MQA | Mitomycin biosynthesis 6-O-methyltransferase | / | 0.443 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.443 | |
| 4hbm | 0Y7 | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.443 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.443 | |
| 4lrz | ADP | PEP-dependent dihydroxyacetone kinase, ADP-binding subunit DhaL | 2.7 | 0.443 | |
| 4qmw | KS1 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.443 | |
| 1bxo | PP7 | Penicillopepsin-1 | 3.4.23.20 | 0.442 | |
| 1c70 | L75 | Protease | / | 0.442 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.442 | |
| 1o0s | NAI | NAD-dependent malic enzyme, mitochondrial | 1.1.1.38 | 0.442 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.442 | |
| 1y4s | ADP | Chaperone protein HtpG | / | 0.442 | |
| 2cd8 | PXI | Cytochrome P450 monooxygenase PikC | / | 0.442 | |
| 2eud | GCQ | Ribonucleoside-diphosphate reductase large chain 1 | 1.17.4.1 | 0.442 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.442 | |
| 2qtv | GNP | Small COPII coat GTPase SAR1 | 3.6.5 | 0.442 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.442 | |
| 3cvu | FAD | RE11660p | / | 0.442 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.442 | |
| 3jqp | A2P | Ferredoxin--NADP reductase, apicoplast | / | 0.442 | |
| 3oji | PYV | Abscisic acid receptor PYL3 | / | 0.442 | |
| 3qa2 | XNA | Ketohexokinase | / | 0.442 | |
| 3zew | STU | Ephrin type-B receptor 4 | 2.7.10.1 | 0.442 | |
| 4aic | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.442 | |
| 4l8u | 9AZ | Serum albumin | / | 0.442 | |
| 4mcb | 21W | tRNA (guanine-N(1)-)-methyltransferase | 2.1.1.228 | 0.442 | |
| 4y93 | 746 | Tyrosine-protein kinase | / | 0.442 | |
| 5bsg | NAP | Pyrroline-5-carboxylate reductase | / | 0.442 | |
| 1e7q | NAP | GDP-L-fucose synthase | / | 0.441 | |
| 1np7 | FAD | Cryptochrome DASH | / | 0.441 | |
| 1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.441 | |
| 1vzd | CB3 | Thymidylate synthase | / | 0.441 | |
| 1ybm | NAP | Uncharacterized protein At5g02240 | / | 0.441 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.441 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 2zdy | ADP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial | 2.7.11.2 | 0.441 | |
| 3c1t | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.441 | |
| 3cd3 | STU | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.441 | |
| 3cls | FAD | Electron transfer flavoprotein subunit alpha | / | 0.441 | |
| 3ey9 | TDP | Pyruvate dehydrogenase [ubiquinone] | 1.2.5.1 | 0.441 | |
| 3iae | D7K | Benzaldehyde lyase | / | 0.441 | |
| 3sp6 | IL2 | Peroxisome proliferator-activated receptor alpha | / | 0.441 | |
| 3tk3 | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.441 | |
| 3v8w | 0G2 | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.441 | |
| 4bcr | WY1 | Peroxisome proliferator-activated receptor alpha | / | 0.441 | |
| 4c58 | 824 | Cyclin-G-associated kinase | 2.7.11.1 | 0.441 | |
| 4dfr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 4l4x | NDP | AmphI | / | 0.441 | |
| 4lxh | C1E | Alpha/beta hydrolase fold | / | 0.441 | |
| 4ocv | ANP | Aminoglycoside phosphotransferase | / | 0.441 | |
| 4px9 | ADP | ATP-dependent RNA helicase DDX3X | 3.6.4.13 | 0.441 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.441 | |
| 4q72 | FAD | Bifunctional protein PutA | / | 0.441 | |
| 1hwz | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.440 | |
| 1j21 | ATP | Argininosuccinate synthase | / | 0.440 | |
| 1noo | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 1nvq | UCN | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 1u59 | STU | Tyrosine-protein kinase ZAP-70 | 2.7.10.2 | 0.440 | |
| 1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.440 | |
| 2iod | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.440 | |
| 2o7p | NAP | Riboflavin biosynthesis protein RibD | / | 0.440 | |
| 2pr2 | DG1 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 2qbl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.440 | |
| 2rl1 | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.440 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.440 | |
| 2xck | MH4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.440 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.440 | |
| 3d2r | ADP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial | 2.7.11.2 | 0.440 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.440 | |
| 3q3c | NAD | NAD-dependent L-serine dehydrogenase | / | 0.440 | |
| 3t11 | 3T1 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 4dpd | DHF | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.440 | |
| 4e73 | 0NR | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.440 | |
| 4qml | ANP | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.440 | |
| 4qmy | STU | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.440 |