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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3zrlZRLGlycogen synthase kinase-3 beta2.7.11.26

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity
Align
3zrlZRLGlycogen synthase kinase-3 beta2.7.11.261.000
3zrmZRMGlycogen synthase kinase-3 beta2.7.11.260.627
3f7z34OGlycogen synthase kinase-3 beta2.7.11.260.596
3zrkZRKGlycogen synthase kinase-3 beta2.7.11.260.595
4acdGR9Glycogen synthase kinase-3 beta2.7.11.260.589
4j1rI5RGlycogen synthase kinase-3 beta2.7.11.260.578
4achKDIGlycogen synthase kinase-3 beta2.7.11.260.576
4afjSJJGlycogen synthase kinase-3 beta2.7.11.260.572
4acc7YGGlycogen synthase kinase-3 beta2.7.11.260.561
2ow3BIMGlycogen synthase kinase-3 beta2.7.11.260.560
4j711JXGlycogen synthase kinase-3 beta2.7.11.260.555
4nm0ADPGlycogen synthase kinase-3 beta2.7.11.260.547
1pyxANPGlycogen synthase kinase-3 beta2.7.11.260.544
4b7tCWTGlycogen synthase kinase-3 beta2.7.11.260.544
1q3dSTUGlycogen synthase kinase-3 beta2.7.11.260.540
3q3b55EGlycogen synthase kinase-3 beta2.7.11.260.540
3sd0TSKGlycogen synthase kinase-3 beta2.7.11.260.535
1q3wATUGlycogen synthase kinase-3 beta2.7.11.260.534
3gb2G3BGlycogen synthase kinase-3 beta2.7.11.260.532
1r0eDFNGlycogen synthase kinase-3 beta2.7.11.260.531
3du8553Glycogen synthase kinase-3 beta2.7.11.260.530
4acg6LQGlycogen synthase kinase-3 beta2.7.11.260.530
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.525
4dit0KDGlycogen synthase kinase-3 beta2.7.11.260.525
2vd5BI8Myotonin-protein kinase2.7.11.10.520
3f883HTGlycogen synthase kinase-3 beta2.7.11.260.520
4nm7ADPGlycogen synthase kinase-3 beta2.7.11.260.519
1q5kTMUGlycogen synthase kinase-3 beta2.7.11.260.512
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.512
1j1cADPGlycogen synthase kinase-3 beta2.7.11.260.511
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.511
1q41IXMGlycogen synthase kinase-3 beta2.7.11.260.505
1uv5BRWGlycogen synthase kinase-3 beta2.7.11.260.502
3zh8C58Protein kinase C iota type2.7.11.130.502
2wmsZYSSerine/threonine-protein kinase Chk12.7.11.10.501
3zep1NXTyrosine-protein kinase JAK32.7.10.20.501
1q4l679Glycogen synthase kinase-3 beta2.7.11.260.500
1zrzBI1Protein kinase C iota type2.7.11.130.498
3i4bZ48Glycogen synthase kinase-3 beta2.7.11.260.498
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.10.496
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.495
2c3kABOSerine/threonine-protein kinase Chk12.7.11.10.494
2i0ePDSProtein kinase C beta type2.7.11.130.494
3r2b05BMAP kinase-activated protein kinase 22.7.11.10.494
2i40BLZCyclin-dependent kinase 22.7.11.220.493
3l1sZ92Glycogen synthase kinase-3 beta2.7.11.260.493
2brgDFYSerine/threonine-protein kinase Chk12.7.11.10.492
2broDF2Serine/threonine-protein kinase Chk12.7.11.10.491
3eb0DRKUncharacterized protein/0.491
3ckxSTUSerine/threonine-protein kinase 242.7.11.10.490
2br1PFPSerine/threonine-protein kinase Chk12.7.11.10.489
4hbm0Y7E3 ubiquitin-protein ligase Mdm26.3.20.488
2ym5YM5Serine/threonine-protein kinase Chk12.7.11.10.487
4fswHK6Serine/threonine-protein kinase Chk12.7.11.10.487
4ftu7HKSerine/threonine-protein kinase Chk12.7.11.10.486
2ym44YMSerine/threonine-protein kinase Chk12.7.11.10.485
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.485
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.485
2cchATPCyclin-dependent kinase 22.7.11.220.484
2e9oA58Serine/threonine-protein kinase Chk12.7.11.10.484
3ag9A02cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.484
3pjcPJCTyrosine-protein kinase JAK32.7.10.20.484
4nm5ADPGlycogen synthase kinase-3 beta2.7.11.260.484
1oi9N20Cyclin-dependent kinase 22.7.11.220.483
4qmxH8HSerine/threonine-protein kinase 242.7.11.10.483
2wxvWXVCyclin-dependent kinase 22.7.11.220.481
3mfsANPPeripheral plasma membrane protein CASK2.7.11.10.481
3vf9477Tyrosine-protein kinase SYK2.7.10.20.481
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.481
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.480
3bheBZNGag-Pol polyprotein3.4.23.160.479
4qnaX11Serine/threonine-protein kinase 242.7.11.10.479
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.478
2gcdSTUSerine/threonine-protein kinase TAO22.7.11.10.478
3p8jFMNPentaerythritol tetranitrate reductase/0.478
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.478
2c3lIDZSerine/threonine-protein kinase Chk12.7.11.10.477
2hog710Serine/threonine-protein kinase Chk12.7.11.10.477
2wmwZYWSerine/threonine-protein kinase Chk12.7.11.10.477
4q71FADBifunctional protein PutA/0.477
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.476
3cd3STUTyrosine-protein kinase Fes/Fps2.7.10.20.476
3hllI45Mitogen-activated protein kinase 14/0.476
4ft0HK9Serine/threonine-protein kinase Chk12.7.11.10.476
1nxkSTUMAP kinase-activated protein kinase 22.7.11.10.475
2wmxZY6Serine/threonine-protein kinase Chk12.7.11.10.475
3ddqRRCCyclin-dependent kinase 22.7.11.220.475
3tnwF18Cyclin-dependent kinase 22.7.11.220.475
4wboANWRhodopsin kinase/0.475
2hxq373Serine/threonine-protein kinase Chk12.7.11.10.474
2r7b2533-phosphoinositide-dependent protein kinase 12.7.11.10.474
3rm618ZCyclin-dependent kinase 22.7.11.220.474
4hvh19RTyrosine-protein kinase JAK32.7.10.20.474
4qmzB49Serine/threonine-protein kinase 242.7.11.10.474
2qhm7CSSerine/threonine-protein kinase Chk12.7.11.10.473
3iw4LW4Protein kinase C alpha type2.7.11.130.473
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.473
4qmuSKESerine/threonine-protein kinase 242.7.11.10.473
1nvrSTUSerine/threonine-protein kinase Chk12.7.11.10.472
1uu9BI33-phosphoinositide-dependent protein kinase 12.7.11.10.472
2wihP48Cyclin-dependent kinase 22.7.11.220.472
4erwSTUCyclin-dependent kinase 22.7.11.220.472
4hyh1AMSerine/threonine-protein kinase Chk12.7.11.10.472
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.471
3m42HGFMAP kinase-activated protein kinase 22.7.11.10.471
2ym3YM3Serine/threonine-protein kinase Chk12.7.11.10.470
3dt1P40Mitogen-activated protein kinase 14/0.470
4dcaADPAminoglycoside phosphotransferase/0.470
1pkdUCNCyclin-dependent kinase 22.7.11.220.469
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.469
3junAJDPhenazine biosynthesis protein A/B/0.469
3r7iX9ICyclin-dependent kinase 22.7.11.220.469
4gk2L66Ephrin type-A receptor 32.7.10.10.469
4gmy0X5Tyrosine-protein kinase JAK2/0.469
4u9aSTUInterleukin-1 receptor-associated kinase 42.7.11.10.468
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.467
2ym7YM7Serine/threonine-protein kinase Chk12.7.11.10.467
4bcnT9NCyclin-dependent kinase 22.7.11.220.467
4g170VNCasein kinase I isoform gamma-32.7.11.10.467
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.466
2b55D31Cyclin-dependent kinase 22.7.11.220.466
2ydiYDISerine/threonine-protein kinase Chk12.7.11.10.466
4dgo0JWCasein kinase II subunit alpha2.7.11.10.466
4fszHK8Serine/threonine-protein kinase Chk12.7.11.10.466
1h1r6CPCyclin-dependent kinase 22.7.11.220.465
1j1bANPGlycogen synthase kinase-3 beta2.7.11.260.465
2brbPFQSerine/threonine-protein kinase Chk12.7.11.10.465
2c6tDT5Cyclin-dependent kinase 22.7.11.220.465
2itqITQEpidermal growth factor receptor2.7.10.10.465
2r0uM54Serine/threonine-protein kinase Chk12.7.11.10.465
2w06FRVCyclin-dependent kinase 22.7.11.220.465
2wmuZYUSerine/threonine-protein kinase Chk12.7.11.10.465
2x1nX1NCyclin-dependent kinase 22.7.11.220.465
3qx4X4BCyclin-dependent kinase 22.7.11.220.465
4eomATPCyclin-dependent kinase 22.7.11.220.465
4oavACP2-5A-dependent ribonuclease3.1.260.465
3juqAJDPhenazine biosynthesis protein A/B/0.464
4ftcH6KSerine/threonine-protein kinase Chk12.7.11.10.464
4g2fC07Ephrin type-A receptor 32.7.10.10.464
4j97ACPFibroblast growth factor receptor 2/0.464
2ghlLIBMitogen-activated protein kinase 14/0.463
2wpa889Cyclin-dependent kinase 22.7.11.220.463
3hdmMMGSerine/threonine-protein kinase Sgk12.7.11.10.463
4bcoT6QCyclin-dependent kinase 22.7.11.220.463
1pjcNADAlanine dehydrogenase/0.462
1x2hLPALipoate-protein ligase A6.3.1.200.462
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.462
3cjfSAVVascular endothelial growth factor receptor 22.7.10.10.462
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.462
4fsmHK1Serine/threonine-protein kinase Chk12.7.11.10.462
4tuvCPZCytochrome P450 1191.140.462
1vyw292Cyclin-dependent kinase 22.7.11.220.461
2aqkNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.461
2b7aIZATyrosine-protein kinase JAK2/0.461
3c50ADPRhodopsin kinase/0.461
3hx4ANPCalmodulin-domain protein kinase 1/0.461
4eok4SPCyclin-dependent kinase 22.7.11.220.461
4qmySTUSerine/threonine-protein kinase 242.7.11.10.461
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.460
2hy0306Serine/threonine-protein kinase Chk12.7.11.10.460
3p84FMNPentaerythritol tetranitrate reductase/0.460
3qc9ADPRhodopsin kinase/0.460
4e5yNDPGDP-L-fucose synthase1.1.1.2710.460
4oa9ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.460
1u54ACPActivated CDC42 kinase 1/0.459
1yvj4STTyrosine-protein kinase JAK32.7.10.20.459
2ym6YM6Serine/threonine-protein kinase Chk12.7.11.10.459
3blrCPBCyclin-dependent kinase 92.7.11.220.459
3frqERYErythromycin resistance repressor protein/0.459
3qqfX07Cyclin-dependent kinase 22.7.11.220.459
3vid4TTVascular endothelial growth factor receptor 22.7.10.10.459
4ftkH9KSerine/threonine-protein kinase Chk12.7.11.10.459
4ix6ADPUncharacterized protein/0.459
1oiyN41Cyclin-dependent kinase 22.7.11.220.458
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.458
2y3sTIRTamL/0.458
3nwxKVSGag-Pol polyprotein3.4.23.160.458
3vjoANPEpidermal growth factor receptor2.7.10.10.458
4hyi1AOSerine/threonine-protein kinase Chk12.7.11.10.458
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.458
5e8wSTUTGF-beta receptor type-12.7.11.300.458
1hbvGANGag-Pol polyprotein/0.457
1oiuN76Cyclin-dependent kinase 22.7.11.220.457
1ouk084Mitogen-activated protein kinase 14/0.457
2ayp43ASerine/threonine-protein kinase Chk12.7.11.10.457
2y4gTIRTamL/0.457
3a62STURibosomal protein S6 kinase beta-12.7.11.10.457
3ddpRC8Cyclin-dependent kinase 22.7.11.220.457
3sheI85MAP kinase-activated protein kinase 32.7.11.10.457
3zc6VFCTyrosine-protein kinase JAK32.7.10.20.457
4ek610KCyclin-dependent kinase 22.7.11.220.457
4qmpDKISerine/threonine-protein kinase 242.7.11.10.457
6cp4CAMCamphor 5-monooxygenase1.14.15.10.457
2qo9ANPEphrin type-A receptor 32.7.10.10.456
2xchCKG3-phosphoinositide-dependent protein kinase 12.7.11.10.456
3cyxROCGag-Pol polyprotein3.4.23.160.456
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.456
3rjc06ZCyclin-dependent kinase 22.7.11.220.456
3zdiUGJGlycogen synthase kinase-3 beta2.7.11.260.456
4l4dCAMCamphor 5-monooxygenase1.14.15.10.456
4mvfSTUCalcium-dependent protein kinase 22.7.11.10.456
1bvrNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.455
1eh4IC1Casein kinase I homolog 12.7.11.10.455
1gij2PUCyclin-dependent kinase 22.7.11.220.455
2b52D42Cyclin-dependent kinase 22.7.11.220.455
2uzlC94Cyclin-dependent kinase 22.7.11.220.455
4qms1N1Serine/threonine-protein kinase 242.7.11.10.455
5bsgNAPPyrroline-5-carboxylate reductase/0.455
1ppjANYCytochrome b/0.454
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.454
2ejvNADL-threonine 3-dehydrogenase/0.454
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.454
2jedLG8Protein kinase C theta type2.7.11.130.454
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.454
2wmtZYTSerine/threonine-protein kinase Chk12.7.11.10.454
4bcpT3CCyclin-dependent kinase 22.7.11.220.454
4nj32KDCyclin-dependent kinase 22.7.11.220.454
4qmtH1NSerine/threonine-protein kinase 242.7.11.10.454
5a9sNAPPutative dehydrogenase/0.454
1rx8NAPDihydrofolate reductase1.5.1.30.453
1sduMK1Gag-Pol polyprotein3.4.23.160.453
1xl2189Gag-Pol polyprotein3.4.23.160.453
2bqvA1AProtease/0.453
2fvdLIACyclin-dependent kinase 22.7.11.220.453
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.453
4bgg844Activin receptor type-12.7.11.300.453
4dx7DM2Multidrug efflux pump subunit AcrB/0.453
4erkOLOMitogen-activated protein kinase 12.7.11.240.453
4f630S7Fibroblast growth factor receptor 1/0.453
4xumIMNPeroxisome proliferator-activated receptor gamma/0.453
5drdATPAurora kinase A2.7.11.10.453
1uu3LY43-phosphoinositide-dependent protein kinase 12.7.11.10.452
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.452
2gdo12CSerine/threonine-protein kinase Chk12.7.11.10.452
2iw84SPCyclin-dependent kinase 22.7.11.220.452
3mfrANPPeripheral plasma membrane protein CASK2.7.11.10.452
4ftm1HKSerine/threonine-protein kinase Chk12.7.11.10.452
4zirANPEnergy-coupling factor transporter ATP-binding protein EcfA23.6.30.452
4zirANPEnergy-coupling factor transporter ATP-binding protein EcfA1/0.452
1v1k3FPCyclin-dependent kinase 22.7.11.220.451
1ykr628Cyclin-dependent kinase 22.7.11.220.451
1yw2PGJMitogen-activated protein kinase 14/0.451
2acxANPG protein-coupled receptor kinase 62.7.11.160.451
3r7uX96Cyclin-dependent kinase 22.7.11.220.451
3roy22ZCyclin-dependent kinase 22.7.11.220.451
3u8w09JMitogen-activated protein kinase 14/0.451
1a72PADAlcohol dehydrogenase E chain1.1.1.10.450
1finATPCyclin-dependent kinase 22.7.11.220.450
1v35NAIEnoyl-ACP reductase/0.450
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.450
2f2cAP9Cyclin-dependent kinase 62.7.11.220.450
3bhtMFRCyclin-dependent kinase 22.7.11.220.450
3cjgKIMVascular endothelial growth factor receptor 22.7.10.10.450
4cd0AWJALK tyrosine kinase receptor2.7.10.10.450
1ungALHCyclin-dependent-like kinase 52.7.11.10.449
2ij7TPFMycocyclosin synthase1.14.21.90.449
3fwfCAMCamphor 5-monooxygenase1.14.15.10.449
3i60E86Mitogen-activated protein kinase 12.7.11.240.449
3oom507Activin receptor type-12.7.11.300.449
3rk909ZCyclin-dependent kinase 22.7.11.220.449
4fsyHK7Serine/threonine-protein kinase Chk12.7.11.10.449
4rrvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.449
2izt23DCasein kinase I isoform gamma-32.7.11.10.448
3l9nL9NcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.448
3r8lZ30Cyclin-dependent kinase 22.7.11.220.448
3rni21ZCyclin-dependent kinase 22.7.11.220.448
4bchT7ZCyclin-dependent kinase 92.7.11.220.448
4cztCPSCBL-interacting serine/threonine-protein kinase 232.7.11.10.448
4ftlH0KSerine/threonine-protein kinase Chk12.7.11.10.448
5fwnNAPPutative dehydrogenase/0.448
1e9hINRCyclin-dependent kinase 22.7.11.220.447
1m78NDPDihydrofolate reductase1.5.1.30.447
1ml6GBXGlutathione S-transferase A22.5.1.180.447
1xddAAYIntegrin alpha-L/0.447
2aquDR7Gag-Pol polyprotein3.4.23.160.447
2cgv3B3Serine/threonine-protein kinase Chk12.7.11.10.447
3emg685Tyrosine-protein kinase SYK2.7.10.20.447
3junAKDPhenazine biosynthesis protein A/B/0.447
3tkh07SSerine/threonine-protein kinase Chk12.7.11.10.447
4gh2HK0Serine/threonine-protein kinase Chk12.7.11.10.447
4hge15VTyrosine-protein kinase JAK2/0.447
1jpaANPEphrin type-B receptor 22.7.10.10.446
1ny3ADPMAP kinase-activated protein kinase 22.7.11.10.446
2oh02PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.446
2x8iX8ISerine/threonine-protein kinase Chk12.7.11.10.446
2xvdAS6Ephrin type-B receptor 42.7.10.10.446
3c4xATPRhodopsin kinase/0.446
3qaqQAQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
3qziX72Cyclin-dependent kinase 22.7.11.220.446
3raiX85Cyclin-dependent kinase 22.7.11.220.446
3s79ASDAromatase1.14.14.140.446
4eutBX7Serine/threonine-protein kinase TBK12.7.11.10.446
4ft5H2KSerine/threonine-protein kinase Chk12.7.11.10.446
4i0s1B5Tyrosine-protein kinase SYK2.7.10.20.446
4l521ULMitogen-activated protein kinase kinase kinase 72.7.11.250.446
4nmdFDABifunctional protein PutA/0.446
4qmnDB8Serine/threonine-protein kinase 242.7.11.10.446
5e8xSTUTGF-beta receptor type-12.7.11.300.446
1hk2T44Serum albumin/0.445
1uvrBI83-phosphoinositide-dependent protein kinase 12.7.11.10.445
1zidZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.445
2dwbANPAurora kinase A2.7.11.10.445
2uzdC85Cyclin-dependent kinase 22.7.11.220.445
2uzeC95Cyclin-dependent kinase 22.7.11.220.445
2wmqZYQSerine/threonine-protein kinase Chk12.7.11.10.445
2xd6XD6ATP-dependent molecular chaperone HSP82/0.445
2xikJ60Serine/threonine-protein kinase 252.7.11.10.445
3friSAH16S rRNA methylase/0.445
3hl7I47Mitogen-activated protein kinase 14/0.445
3ssnMVIMycinamicin VI 2''-O-methyltransferase/0.445
3zvvXAZPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
4dqh017Gag-Pol polyprotein/0.445
4gk4L90Ephrin type-A receptor 32.7.10.10.445
4p6wMOFGlucocorticoid receptor/0.445
1d7yFADFerredoxin reductase/0.444
1k2b0Q4Gag-Pol polyprotein3.4.23.160.444
1xjdSTUProtein kinase C theta type2.7.11.130.444
2bhhRYUCyclin-dependent kinase 22.7.11.220.444
2ijmATPFocal adhesion kinase 12.7.10.20.444
2pziAXXSerine/threonine-protein kinase PknG2.7.11.10.444
2xf04UBSerine/threonine-protein kinase Chk12.7.11.10.444
2yn8STUEphrin type-B receptor 42.7.10.10.444
2z54AB1Gag-Pol polyprotein3.4.23.160.444
3qwkX62Cyclin-dependent kinase 22.7.11.220.444
3r7eX88Cyclin-dependent kinase 22.7.11.220.444
3r9hZ67Cyclin-dependent kinase 22.7.11.220.444
4ct1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.444
4dbzNDPPutative ketoacyl reductase1.3.10.444
4jboWPHAurora kinase A2.7.11.10.444
4kkyCAMCamphor 5-monooxygenase1.14.15.10.444
4l4fCAMCamphor 5-monooxygenase1.14.15.10.444
4o0wADNAurora kinase A2.7.11.10.444
4rqvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.444
5dr2ATPAurora kinase A2.7.11.10.444
1cbfSAHCobalt-precorrin-4 C(11)-methyltransferase2.1.1.2710.443
1g5sI17Cyclin-dependent kinase 22.7.11.220.443
1qvrANPChaperone protein ClpB/0.443
2idzZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.443
2r5tANPSerine/threonine-protein kinase Sgk12.7.11.10.443
2wyvNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.443
2ym8YM8Serine/threonine-protein kinase Chk12.7.11.10.443
3cblSTUTyrosine-protein kinase Fes/Fps2.7.10.20.443
3fwiCAMCamphor 5-monooxygenase1.14.15.10.443
3uli1N3Cyclin-dependent kinase 22.7.11.220.443
4l9i8PRRhodopsin kinase/0.443
5akk1P8Bifunctional epoxide hydrolase 23.1.3.760.443
1fvv107Cyclin-dependent kinase 22.7.11.220.442
1okySTU3-phosphoinositide-dependent protein kinase 12.7.11.10.442
1ouy094Mitogen-activated protein kinase 14/0.442
2brhDFWSerine/threonine-protein kinase Chk12.7.11.10.442
2itpAEEEpidermal growth factor receptor2.7.10.10.442
2py3ACPFibroblast growth factor receptor 2/0.442
2uxoTACHTH-type transcriptional regulator TtgR/0.442
2z97CAMCamphor 5-monooxygenase1.14.15.10.442
3a8wATPProtein kinase C iota type2.7.11.130.442
3mj5GRMReplicase polyprotein 1a3.4.220.442
3ncgBK1Calmodulin-domain protein kinase 1, putative/0.442
3r0tFU9Casein kinase II subunit alpha2.7.11.10.442
3rukAERSteroid 17-alpha-hydroxylase/17,20 lyase/0.442
3t113T1Gag-Pol polyprotein3.4.23.160.442
3tucFPWTyrosine-protein kinase SYK2.7.10.20.442
4ft9H4KSerine/threonine-protein kinase Chk12.7.11.10.442
4ftq4HKSerine/threonine-protein kinase Chk12.7.11.10.442
4gub0Y4Casein kinase II subunit alpha2.7.11.10.442
4gyzD5MTyrosyl-DNA phosphodiesterase 23.1.40.442
4n6hEJ4Delta-type opioid receptor/0.442
4q73FADBifunctional protein PutA/0.442
5ackATP3-phosphoinositide-dependent protein kinase 12.7.11.10.442
1t85CAMCamphor 5-monooxygenase1.14.15.10.441
2chz093Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
2e0aANP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial2.7.11.20.441
2hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.441
2vx07X7Ephrin type-B receptor 42.7.10.10.441
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.441
2y3rTRKTamL/0.441
3bqcEMOCasein kinase II subunit alpha2.7.11.10.441
3cgcFADCoenzyme A disulfide reductase/0.441
3ezrEZRCyclin-dependent kinase 22.7.11.220.441
3mdmFJZCholesterol 24-hydroxylase/0.441
3my5RFZCyclin-dependent kinase 22.7.11.220.441
3nww3NWMitogen-activated protein kinase 14/0.441
3qtqX35Cyclin-dependent kinase 22.7.11.220.441
3qu0X40Cyclin-dependent kinase 22.7.11.220.441
3uyt0CKCasein kinase I isoform delta2.7.11.10.441
4acm7YGCyclin-dependent kinase 22.7.11.220.441
4aw0ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.441
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.441
4c58824Cyclin-G-associated kinase2.7.11.10.441
4enhFVXCholesterol 24-hydroxylase/0.441
4fl1ANPTyrosine-protein kinase SYK2.7.10.20.441
4g160VMCasein kinase I isoform gamma-32.7.11.10.441
4gj30XPNon-receptor tyrosine-protein kinase TYK22.7.10.20.441
4ienCOAPutative acyl-CoA hydrolase/0.441
4jia1K3Tyrosine-protein kinase JAK2/0.441
4lopSB4Mitogen-activated protein kinase 14/0.441
1ke9LS5Cyclin-dependent kinase 22.7.11.220.440
1oecAA2Fibroblast growth factor receptor 2/0.440
1q8wM77cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.440
1u2yGOXPancreatic alpha-amylase/0.440
1uu8BI13-phosphoinositide-dependent protein kinase 12.7.11.10.440
2cdz23DSerine/threonine-protein kinase PAK 42.7.11.10.440
2ev9NAPShikimate dehydrogenase (NADP(+))/0.440
2ojf4PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.440
3at3ATKCasein kinase II subunit alpha2.7.11.10.440
3em0CHDFatty acid-binding protein 6, ileal (gastrotropin)/0.440
3h4lANPDNA mismatch repair protein PMS1/0.440
3iaeD7KBenzaldehyde lyase/0.440
3ibqATPPyridoxal kinase/0.440
3iw1ASDSteroid C26-monooxygenase1.14.13.1410.440
3s4qNK0Mitogen-activated protein kinase 14/0.440
3sc13S13-phosphoinositide-dependent protein kinase 12.7.11.10.440
3wblPDYCyclin-dependent kinase 22.7.11.220.440
4c9oCAMCytochrome P450/0.440
4dfn0K1Tyrosine-protein kinase SYK2.7.10.20.440
4ew2DXYTrifunctional purine biosynthetic protein adenosine-32.1.2.20.440
4fjyFJYPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
4fsqHK3Serine/threonine-protein kinase Chk12.7.11.10.440
4gfo0X2Non-receptor tyrosine-protein kinase TYK22.7.10.20.440
4hbgNDP3-oxoacyl-[acyl-carrier-protein] reductase1.1.1.1000.440
4i22IREEpidermal growth factor receptor2.7.10.10.440
4ix5ANPUncharacterized protein/0.440
4loqSB4Mitogen-activated protein kinase 14/0.440
5c8wPCGcGMP-dependent protein kinase 22.7.11.120.440
5cvhADPCasein kinase II subunit alpha2.7.11.10.440