Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3w77 | FMN | FMN-dependent NADH-azoreductase |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3w77 | FMN | FMN-dependent NADH-azoreductase | / | 1.000 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.499 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.490 | |
| 1dds | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.488 | |
| 1ra3 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.488 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.488 | |
| 1ra8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.485 | |
| 1jtv | TES | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.484 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.484 | |
| 4twr | NAD | NAD binding site:NAD-dependent epimerase/dehydratase:UDP-glucose 4-epimerase | / | 0.483 | |
| 1a72 | PAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.482 | |
| 2fn7 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.482 | |
| 3vqs | JT1 | Genome polyprotein | / | 0.482 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.481 | |
| 4b4w | 9L9 | Bifunctional protein FolD | / | 0.481 | |
| 3zbr | NAP | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.480 | |
| 2dhf | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.479 | |
| 1szf | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.478 | |
| 3e32 | ED2 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.478 | |
| 3n0h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.478 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.477 | |
| 2geu | COK | Pantothenate kinase | 2.7.1.33 | 0.477 | |
| 3fp0 | FP0 | 15-O-acetyltransferase | / | 0.477 | |
| 1rd7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.475 | |
| 2oc9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.475 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.475 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.474 | |
| 4a86 | H35 | Major pollen allergen Bet v 1-A | / | 0.473 | |
| 4f9g | C2E | Stimulator of interferon genes protein | / | 0.473 | |
| 4k6m | SAH | Genome polyprotein | / | 0.473 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.472 | |
| 1dgm | ADN | Adenosine kinase | 2.7.1.20 | 0.471 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.471 | |
| 3gqv | NAP | Enoyl reductase LovC | 1 | 0.471 | |
| 4f6w | 0SS | Cyclin-dependent kinase 8 | 2.7.11.22 | 0.471 | |
| 1tll | FMN | Nitric oxide synthase, brain | 1.14.13.39 | 0.470 | |
| 2bjf | DXC | Choloylglycine hydrolase | 3.5.1.24 | 0.470 | |
| 2iyf | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.470 | |
| 2xtn | GTP | GTPase IMAP family member 2 | / | 0.470 | |
| 4m6j | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.470 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.469 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.469 | |
| 2gmh | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.469 | |
| 2i7p | ACO | Pantothenate kinase 3 | 2.7.1.33 | 0.469 | |
| 2owu | SAH | Diphthine synthase | / | 0.469 | |
| 3nxx | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.469 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.469 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.468 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.468 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.468 | |
| 1yqz | COA | Coenzyme A disulfide reductase | / | 0.467 | |
| 4bge | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.467 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.466 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.466 | |
| 4w5k | PLP | Aspartate aminotransferase, mitochondrial | / | 0.466 | |
| 1rb3 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
| 2ewm | NAD | (S)-1-Phenylethanol dehydrogenase | 1.1.1.311 | 0.465 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.465 | |
| 3qls | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
| 1ju9 | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.464 | |
| 1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 1q5m | NDP | Prostaglandin-E(2) 9-reductase | 1.1.1.189 | 0.464 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.464 | |
| 2gvd | FKP | Adenylate cyclase type 2 | / | 0.464 | |
| 2gvd | FKP | Adenylate cyclase type 5 | / | 0.464 | |
| 2ien | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.464 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.464 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.464 | |
| 5ein | NAP | [LysW]-L-2-aminoadipate 6-phosphate reductase | / | 0.464 | |
| 1dr2 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
| 1dyi | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
| 1gtr | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.463 | |
| 3b70 | NAP | Enoyl reductase LovC | 1 | 0.463 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.463 | |
| 3eks | CY9 | Actin-5C | / | 0.463 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.463 | |
| 1vi2 | NAD | Quinate/shikimate dehydrogenase | / | 0.462 | |
| 2v16 | C47 | Renin | 3.4.23.15 | 0.462 | |
| 2w9h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.462 | |
| 4bgi | I4I | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.462 | |
| 4gb9 | 0WR | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.462 | |
| 1t4c | COA | Formyl-CoA:oxalate CoA-transferase | / | 0.461 | |
| 1xel | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.461 | |
| 3eu5 | GBO | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.461 | |
| 3otb | DGT | Probable tRNA(His) guanylyltransferase | 2.7.7.79 | 0.461 | |
| 3own | 3OX | Renin | 3.4.23.15 | 0.461 | |
| 4df2 | FMN | NADPH dehydrogenase | / | 0.461 | |
| 4emt | C2E | Stimulator of interferon genes protein | / | 0.461 | |
| 4gz6 | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.461 | |
| 4yag | NAI | C alpha-dehydrogenase | / | 0.461 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.460 | |
| 2fy4 | COA | Choline O-acetyltransferase | 2.3.1.6 | 0.460 | |
| 2r2l | PB9 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.460 | |
| 2rir | NAP | Dipicolinate synthase subunit A | / | 0.460 | |
| 2yq9 | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.460 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.460 | |
| 4nd2 | A3D | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.460 | |
| 1dhf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 1kfb | IGP | Tryptophan synthase alpha chain | / | 0.459 | |
| 1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.459 | |
| 1pjc | NAD | Alanine dehydrogenase | / | 0.459 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.459 | |
| 2uuv | FAD | Alkyldihydroxyacetonephosphate synthase | 2.5.1.26 | 0.459 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.459 | |
| 3e33 | ED7 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.459 | |
| 3w8e | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.459 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.459 | |
| 4lol | 1YE | Stimulator of interferon genes protein | / | 0.459 | |
| 1cs4 | FOK | Adenylate cyclase type 2 | / | 0.458 | |
| 1cs4 | FOK | Adenylate cyclase type 5 | / | 0.458 | |
| 2hdj | NDP | Aldo-keto reductase family 1 member C2 | / | 0.458 | |
| 2jkv | NAP | 6-phosphogluconate dehydrogenase, decarboxylating | 1.1.1.44 | 0.458 | |
| 2rcy | NAP | Pyrroline-5-carboxylate reductase | / | 0.458 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.458 | |
| 3m2v | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.458 | |
| 4hbg | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.458 | |
| 4hmz | 18T | dTDP-4-dehydro-6-deoxyglucose 3-epimerase | 5.1.3.27 | 0.458 | |
| 4x5h | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 4yj2 | GTP | Tubulin alpha-1B chain | / | 0.458 | |
| 5adh | APR | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.458 | |
| 1lf2 | R37 | Plasmepsin-2 | 3.4.23.39 | 0.457 | |
| 2f3r | G5P | Guanylate kinase | 2.7.4.8 | 0.457 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.457 | |
| 2ggs | NDP | dTDP-4-dehydrorhamnose reductase | / | 0.457 | |
| 3elu | SAM | Methyltransferase | / | 0.457 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.457 | |
| 1jol | FFO | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 2c1b | CQP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.456 | |
| 2eud | GCQ | Ribonucleoside-diphosphate reductase large chain 1 | 1.17.4.1 | 0.456 | |
| 3eku | CY9 | Actin-5C | / | 0.456 | |
| 3iqh | TYR_ASP_ILE | Cysteine synthase | 2.5.1.47 | 0.456 | |
| 3qd4 | 3Q6 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.456 | |
| 3qwb | NDP | Probable quinone oxidoreductase | 1.6.5.5 | 0.456 | |
| 2x0i | NAI | Malate dehydrogenase | / | 0.455 | |
| 3img | BZ3 | Pantothenate synthetase | 6.3.2.1 | 0.455 | |
| 3rtn | RTN | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
| 3s3v | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.455 | |
| 4j0v | 1H7 | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 1l2t | ATP | Uncharacterized ABC transporter ATP-binding protein MJ0796 | / | 0.454 | |
| 1ps9 | MDE | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.454 | |
| 1psa | 0ZL | Pepsin A | 3.4.23.1 | 0.454 | |
| 1ra3 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 2clq | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.454 | |
| 2dsg | SAH | Diphthine synthase | / | 0.454 | |
| 2dv4 | SAH | Diphthine synthase | / | 0.454 | |
| 2e15 | SAH | Diphthine synthase | / | 0.454 | |
| 2qbm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.454 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.454 | |
| 4x5i | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 1dyj | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 1ia1 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 1n4p | CYS_VAL_ILE_LEU_GER | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.453 | |
| 1qlh | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.453 | |
| 1tqf | 32P | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
| 2dfv | NAD | L-threonine 3-dehydrogenase | / | 0.453 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.453 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.453 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.453 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.453 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.453 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.453 | |
| 5dhh | DGW | Nociceptin receptor | / | 0.453 | |
| 1e5q | NDP | Saccharopine dehydrogenase [NADP(+), L-glutamate-forming] | 1.5.1.10 | 0.452 | |
| 1icq | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.452 | |
| 1k8y | 13P | Tryptophan synthase alpha chain | / | 0.452 | |
| 1o1s | 1NH | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.452 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.452 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.452 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.452 | |
| 2ztm | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.452 | |
| 3iae | D7K | Benzaldehyde lyase | / | 0.452 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 3vdq | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.452 | |
| 4eph | 0RK | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.452 | |
| 4i8z | G08 | Gag-Pol polyprotein | 3.4.23.16 | 0.452 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.452 | |
| 1qx4 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.451 | |
| 1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.451 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.451 | |
| 2e0n | SAH | Precorrin-2 C20-methyltransferase | / | 0.451 | |
| 2fr0 | NDP | 6-deoxyerythronolide-B synthase EryA1, modules 1 and 2 | / | 0.451 | |
| 2q2v | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.451 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.451 | |
| 2ztl | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.451 | |
| 3b6z | CO7 | Enoyl reductase LovC | 1 | 0.451 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.451 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.451 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.451 | |
| 4dfr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 4er6 | AW2 | Histone-lysine N-methyltransferase, H3 lysine-79 specific | 2.1.1.43 | 0.451 | |
| 1hbv | GAN | Gag-Pol polyprotein | / | 0.450 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 2ges | COK | Pantothenate kinase | 2.7.1.33 | 0.450 | |
| 2gjn | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.450 | |
| 3eld | SFG | Methyltransferase | / | 0.450 | |
| 3u9f | CLM | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.450 | |
| 4blr | UTP | NTPase P4 | / | 0.450 | |
| 4eyw | L0R | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.450 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 4gcm | NAP | Thioredoxin reductase | 1.8.1.9 | 0.450 | |
| 4x5j | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1bil | 0IU | Renin | 3.4.23.15 | 0.449 | |
| 1dr5 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.449 | |
| 1w0k | ADP | ATP synthase subunit alpha, mitochondrial | / | 0.449 | |
| 1w0k | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.449 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.449 | |
| 2dte | NAI | Glucose 1-dehydrogenase related protein | / | 0.449 | |
| 2ev9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.449 | |
| 2pci | SAH | Diphthine synthase | / | 0.449 | |
| 2pck | SAH | Diphthine synthase | / | 0.449 | |
| 2qs3 | UBE | Glutamate receptor ionotropic, kainate 1 | / | 0.449 | |
| 3pw8 | ACO | 1,2-phenylacetyl-CoA epoxidase, subunit A | 1.14.13.149 | 0.449 | |
| 4a87 | NAR | Major pollen allergen Bet v 1-A | / | 0.449 | |
| 4an4 | DUD | Putative glycosyl transferase | / | 0.449 | |
| 4bj9 | UHB | Tankyrase-2 | 2.4.2.30 | 0.449 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.449 | |
| 4ie6 | UN9 | Alpha-ketoglutarate-dependent dioxygenase FTO | / | 0.449 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.449 | |
| 1h60 | STR | Pentaerythritol tetranitrate reductase | / | 0.448 | |
| 1ju2 | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.448 | |
| 1ld7 | U66 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.448 | |
| 1s63 | 778 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.448 | |
| 1xl5 | 190 | Gag-Pol polyprotein | 3.4.23.16 | 0.448 | |
| 2a9y | 26A | Adenosine kinase | 2.7.1.20 | 0.448 | |
| 2dv7 | SAH | Diphthine synthase | / | 0.448 | |
| 2ed4 | NAD | 4-hydroxyphenylacetate 3-monooxygenase reductase component | 1.5.1.36 | 0.448 | |
| 2w3b | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 2wvm | GDD | Mannosyl-3-phosphogylcerate synthase | / | 0.448 | |
| 3p8z | SAH | Genome polyprotein | 2.1.1.56 | 0.448 | |
| 3s87 | ADP | Ribonucleoside-diphosphate reductase large chain 1 | 1.17.4.1 | 0.448 | |
| 4a6b | QG8 | Gag-Pol polyprotein | 3.4.23.16 | 0.448 | |
| 4ef4 | C2E | Stimulator of interferon genes protein | / | 0.448 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.447 | |
| 1i7p | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.447 | |
| 1kvu | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.447 | |
| 1re7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.447 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.447 | |
| 2drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 2e8r | SAH | Diphthine synthase | / | 0.447 | |
| 2eeq | SAH | Diphthine synthase | / | 0.447 | |
| 2hut | SAH | Diphthine synthase | / | 0.447 | |
| 2npi | ATP | mRNA cleavage and polyadenylation factor CLP1 | / | 0.447 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.447 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.447 | |
| 3d3w | NAP | L-xylulose reductase | 1.1.1.10 | 0.447 | |
| 3khu | UPG | UDP-glucose 6-dehydrogenase | 1.1.1.22 | 0.447 | |
| 3nl6 | TPS | Uncharacterized protein | / | 0.447 | |
| 3to6 | LYS_CMC | Histone acetyltransferase ESA1 | / | 0.447 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.447 | |
| 4c36 | ZO9 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.447 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.447 | |
| 4yai | NAI | C alpha-dehydrogenase | / | 0.447 | |
| 4ydd | MD1 | DMSO reductase family type II enzyme, molybdopterin subunit | / | 0.447 | |
| 1c6y | MK1 | Protease | / | 0.446 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.446 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.446 | |
| 1h73 | ANP | Homoserine kinase | 2.7.1.39 | 0.446 | |
| 1mja | COA | Histone acetyltransferase ESA1 | / | 0.446 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.446 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.446 | |
| 2d0k | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 2xy3 | DUP | SPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS | 3.6.1.23 | 0.446 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.446 | |
| 3och | 2MX | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 4bc7 | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.446 | |
| 4g74 | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.446 | |
| 4k28 | NAD | Shikimate dehydrogenase family protein | / | 0.446 | |
| 4ms1 | 381 | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.446 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.446 | |
| 1fdt | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.445 | |
| 1j1z | ATP | Argininosuccinate synthase | / | 0.445 | |
| 1j49 | NAD | D-lactate dehydrogenase | 1.1.1.28 | 0.445 | |
| 3dv3 | MEK | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.445 | |
| 3jsx | CC2 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.445 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.445 | |
| 1ddr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1fy7 | COA | Histone acetyltransferase ESA1 | / | 0.444 | |
| 1g8j | MGD | Arsenite oxidase subunit AioA | 1.20.9.1 | 0.444 | |
| 1jd0 | AZM | Carbonic anhydrase 12 | 4.2.1.1 | 0.444 | |
| 1orr | NAD | CDP-paratose 2-epimerase | / | 0.444 | |
| 2a0w | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.444 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.444 | |
| 2e8q | SAH | Diphthine synthase | / | 0.444 | |
| 3l63 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 4ctj | SAM | Genome polyprotein | / | 0.444 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.444 | |
| 4qxq | 1YE | Stimulator of interferon genes protein | / | 0.444 | |
| 4qys | PLR | Tryptophan synthase beta chain 2 | 4.2.1.20 | 0.444 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.444 | |
| 1g54 | FFB | Carbonic anhydrase 2 | 4.2.1.1 | 0.443 | |
| 1h61 | PDN | Pentaerythritol tetranitrate reductase | / | 0.443 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.443 | |
| 1jdv | ADN | Purine nucleoside phosphorylase | / | 0.443 | |
| 1lbc | CYZ | Glutamate receptor 2 | / | 0.443 | |
| 1lf3 | EH5 | Plasmepsin-2 | 3.4.23.39 | 0.443 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1opm | IYG | Peptidyl-glycine alpha-amidating monooxygenase | 1.14.17.3 | 0.443 | |
| 1rx8 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 2aba | STR | Pentaerythritol tetranitrate reductase | / | 0.443 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.443 | |
| 2egs | SAH | Diphthine synthase | / | 0.443 | |
| 2ejz | SAH | Diphthine synthase | / | 0.443 | |
| 2hk9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.443 | |
| 2p5c | SAH | Diphthine synthase | / | 0.443 | |
| 2vou | FAD | 2,6-dihydroxypyridine 3-monooxygenase | 1.14.13.10 | 0.443 | |
| 2z6r | SAH | Diphthine synthase | / | 0.443 | |
| 3cne | FMN | Putative protease I | / | 0.443 | |
| 3gfb | NAD | L-threonine 3-dehydrogenase | / | 0.443 | |
| 3ljt | LA3 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.443 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.443 | |
| 3ox4 | NAD | Alcohol dehydrogenase 2 | 1.1.1.1 | 0.443 | |
| 4bv9 | NDP | Ketimine reductase mu-crystallin | 1.5.1.25 | 0.443 | |
| 4fj0 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.443 | |
| 4y9q | C2E | Uncharacterized protein | / | 0.443 | |
| 4z38 | FMN | MlnA | / | 0.443 | |
| 1lwi | NAP | 3-alpha-hydroxysteroid dehydrogenase | 1.1.1.50 | 0.442 | |
| 1m0b | 0ZQ | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 1rsz | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.442 | |
| 1udb | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.442 | |
| 2e17 | SAH | Diphthine synthase | / | 0.442 | |
| 2fxv | 5GP | Xanthine phosphoribosyltransferase | 2.4.2.22 | 0.442 | |
| 2pxa | SAH | Genome polyprotein | 2.7.7.48 | 0.442 | |
| 2v2q | NVG | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.442 | |
| 2vyq | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.442 | |
| 3ai2 | NDP | NADPH-sorbose reductase | / | 0.442 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 3g5s | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.442 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.442 | |
| 3lzs | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 3pft | FMN | Flavin reductase | / | 0.442 | |
| 4opg | FDA | Conserved Archaeal protein | / | 0.442 | |
| 4rvn | COA | Phenylacetate-coenzyme A ligase | / | 0.442 | |
| 1cdo | NAD | Alcohol dehydrogenase 1 | 1.1.1.1 | 0.441 | |
| 1jcq | 739 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.441 | |
| 1mjb | ACO | Histone acetyltransferase ESA1 | / | 0.441 | |
| 1mvt | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1s20 | NAD | 2,3-diketo-L-gulonate reductase | 1.1.1.130 | 0.441 | |
| 1xl8 | 152 | Peroxisomal carnitine O-octanoyltransferase | 2.3.1.137 | 0.441 | |
| 2ed3 | SAH | Diphthine synthase | / | 0.441 | |
| 2h3w | HC5 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.441 | |
| 2qc8 | ADP | Glutamine synthetase | 6.3.1.2 | 0.441 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.441 | |
| 2rh9 | IGP | Tryptophan synthase alpha chain | / | 0.441 | |
| 3cgt | BCD | Cyclomaltodextrin glucanotransferase | 2.4.1.19 | 0.441 | |
| 3gvh | NAD | Malate dehydrogenase | / | 0.441 | |
| 3iqi | ASN_GLU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.441 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 3sqx | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.441 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.441 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.441 | |
| 4cf6 | CBD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.441 | |
| 4hxy | NDP | Plm1 | / | 0.441 | |
| 4nwz | FAD | FAD-dependent pyridine nucleotide-disulfide oxidoreductase | / | 0.441 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 1e3l | NAD | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.440 | |
| 1il0 | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.440 | |
| 1kvs | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.440 | |
| 1ld8 | U49 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.440 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 1sa4 | JAN | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.440 | |
| 1wng | SAH | Diphthine synthase | / | 0.440 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.440 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.440 | |
| 2jds | L20 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.440 | |
| 2q46 | NAP | Uncharacterized protein At5g02240 | / | 0.440 | |
| 3hyo | ADP | Pyridoxal kinase | / | 0.440 | |
| 3i0p | NAD | Malate dehydrogenase, putative | / | 0.440 | |
| 3img | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.440 | |
| 3s79 | ASD | Aromatase | 1.14.14.14 | 0.440 | |
| 4cvm | ANP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.440 | |
| 4fxy | 0W2 | Neurolysin, mitochondrial | 3.4.24.16 | 0.440 | |
| 4g6g | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.440 | |
| 4gtr | 7TR | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.440 | |
| 4nvk | 2NY | Peroxidase | / | 0.440 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.440 | |
| 4yp1 | 2BA | Stimulator of interferon genes protein | / | 0.440 |