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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1revTB9Gag-Pol polyprotein2.7.7.49

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
1revTB9Gag-Pol polyprotein2.7.7.491.000
1tktH12Gag-Pol polyprotein2.7.7.490.708
1tkzH16Gag-Pol polyprotein2.7.7.490.696
1tl1H18Gag-Pol polyprotein2.7.7.490.657
1s1wUC1Gag-Pol polyprotein2.7.7.490.635
1c1bGCAGag-Pol polyprotein2.7.7.490.633
3i0rRT3Gag-Pol polyprotein2.7.7.490.633
1vruAAPGag-Pol polyprotein2.7.7.490.627
2opqHBQGag-Pol polyprotein2.7.7.490.616
1tl3H20Gag-Pol polyprotein2.7.7.490.615
1hnvTBOGag-Pol polyprotein2.7.7.490.609
1ikwEFZGag-Pol polyprotein2.7.7.490.607
1rt4UC1Gag-Pol polyprotein2.7.7.490.607
4i7fNVEGag-Pol polyprotein2.7.7.490.603
1ikxPNUGag-Pol polyprotein2.7.7.490.598
2hndNVPGag-Pol polyprotein2.7.7.490.597
3ffi3OBGag-Pol polyprotein2.7.7.490.596
1hquHBYGag-Pol polyprotein2.7.7.490.593
2vg7NNIGag-Pol polyprotein2.7.7.490.589
1hpzAAPGag-Pol polyprotein2.7.7.490.580
2rf2MRXGag-Pol polyprotein2.7.7.490.577
1s9eADBGag-Pol polyprotein2.7.7.490.576
3megT27Gag-Pol polyprotein2.7.7.490.576
1ikvEFZGag-Pol polyprotein2.7.7.490.573
3meeT27Gag-Pol polyprotein2.7.7.490.573
2ze2T27Gag-Pol polyprotein2.7.7.490.571
4ko0JLJGag-Pol polyprotein2.7.7.490.570
2vg5NNCGag-Pol polyprotein2.7.7.490.565
1rt2TNKGag-Pol polyprotein2.7.7.490.563
2ban357Gag-Pol polyprotein2.7.7.490.562
4i2pG73Gag-Pol polyprotein2.7.7.490.561
1tvrTB9Gag-Pol polyprotein2.7.7.490.555
3di6PDZGag-Pol polyprotein2.7.7.490.555
3i0sRT7Gag-Pol polyprotein2.7.7.490.554
1rt5UC2Gag-Pol polyprotein2.7.7.490.553
1tkxGWBGag-Pol polyprotein2.7.7.490.552
4g1qT27Gag-Pol polyprotein2.7.7.490.552
4id5T27Gag-Pol polyprotein2.7.7.490.552
2zd1T27Gag-Pol polyprotein2.7.7.490.551
4ig3T27Gag-Pol polyprotein2.7.7.490.549
3is9AC7Gag-Pol polyprotein2.7.7.490.547
1fk9EFZGag-Pol polyprotein2.7.7.490.545
1s6qTPBGag-Pol polyprotein2.7.7.490.544
4kko1REGag-Pol polyprotein2.7.7.490.544
1eetBFUGag-Pol polyprotein2.7.7.490.542
1hniAAAGag-Pol polyprotein2.7.7.490.541
1ikyMSDGag-Pol polyprotein2.7.7.490.539
1ep4S11Gag-Pol polyprotein2.7.7.490.538
3qlhT27Gag-Pol polyprotein2.7.7.490.531
3m8qDJZGag-Pol polyprotein2.7.7.490.529
2hnzPC0Gag-Pol polyprotein2.7.7.490.528
3nbpJGZGag-Pol polyprotein2.7.7.490.524
1jlgUC1Gag-Pol polyprotein2.7.7.490.522
2oppHBQGag-Pol polyprotein2.7.7.490.521
3m8p65BGag-Pol polyprotein2.7.7.490.515
3lamKRPGag-Pol polyprotein2.7.7.490.512
5cyqT27Gag-Pol polyprotein2.7.7.490.512
4i2q1BTGag-Pol polyprotein2.7.7.490.508
3dleGFAGag-Pol polyprotein2.7.7.490.506
2opsHBQGag-Pol polyprotein2.7.7.490.505
3lanKBTGag-Pol polyprotein2.7.7.490.503
3mec65BGag-Pol polyprotein2.7.7.490.501
3med65BGag-Pol polyprotein2.7.7.490.499
2ibzSMACytochrome b/0.496
1jlqSBNGag-Pol polyprotein2.7.7.490.495
2rkiTT1Gag-Pol polyprotein2.7.7.490.493
3dolGWIPol protein/0.486
3eel53TUncharacterized protein/0.486
1ezvSMACytochrome b/0.485
1kyoSMACytochrome b/0.484
3cx5SMACytochrome b/0.484
1klmSPPGag-Pol polyprotein2.7.7.490.482
1rt1MKCGag-Pol polyprotein2.7.7.490.482
1v7aFRCAdenosine deaminase3.5.4.40.482
4a33MYAGlycylpeptide N-tetradecanoyltransferase/0.482
1rt7UC4Gag-Pol polyprotein2.7.7.490.481
4h9614QDihydrofolate reductase1.5.1.30.481
4nb6444Nuclear receptor ROR-gamma/0.480
3sgx0FWDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.479
3cxhSMACytochrome b/0.478
3dl9V2HVitamin D 25-hydroxylase/0.476
4a2zMYAGlycylpeptide N-tetradecanoyltransferase/0.476
4a32MYAGlycylpeptide N-tetradecanoyltransferase/0.476
4lmuQUESerine/threonine-protein kinase pim-12.7.11.10.476
2ph5NADHomospermidine synthase/0.475
2yee2ECHeat shock protein HSP 90-alpha/0.475
2zv2609Calcium/calmodulin-dependent protein kinase kinase 22.7.11.170.475
4c2xNHWGlycylpeptide N-tetradecanoyltransferase 2/0.475
5a3bAPRSIR2 family protein/0.475
1fduESTEstradiol 17-beta-dehydrogenase 11.1.1.620.474
2z7gEH9Adenosine deaminase3.5.4.40.474
3p9tTCLRepressor/0.474
2vn0TDZCytochrome P450 2C8/0.473
3dmjGWEPol protein/0.473
3eej53RUncharacterized protein/0.473
3irxUDRGag-Pol polyprotein2.7.7.490.473
4grb0XGCasein kinase II subunit alpha2.7.11.10.473
4hbgNDP3-oxoacyl-[acyl-carrier-protein] reductase1.1.1.1000.473
4ug71EVNitric oxide synthase oxygenase1.14.13.1650.473
3mfsANPPeripheral plasma membrane protein CASK2.7.11.10.472
3qlxQLRUncharacterized protein/0.472
4ezj0SCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.472
4gkh0J9Aminoglycoside 3'-phosphotransferase AphA1-IAB/0.472
1ia2TQ4Dihydrofolate reductase1.5.1.30.471
1kb9SMACytochrome b/0.471
2qjySMACytochrome b/0.471
4rw6494Gag-Pol polyprotein2.7.7.490.471
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.470
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.470
4ele31IDihydrofolate reductase/0.470
2w9sTOPDihydrofolate reductase type 1 from Tn40031.5.1.30.469
3el8PD5Proto-oncogene tyrosine-protein kinase Src2.7.10.20.469
3hz5Z64Heat shock protein HSP 90-alpha/0.469
3of2NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.469
4ktkKTKCytochrome P450/0.469
1yc2NADNAD-dependent protein deacylase 2/0.468
2wufKEM4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase3.7.1.170.468
2yiuSMACytochrome b/0.468
3irm1CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.468
3t3q9PLCytochrome P450 2A61.14.130.468
1jlcFTCGag-Pol polyprotein2.7.7.490.467
1o5rFR9Adenosine deaminase3.5.4.40.467
1rdt570Peroxisome proliferator-activated receptor gamma/0.467
3ixp834Ecdysone receptor/0.467
3ua506XCytochrome P450 2B61.14.130.467
1m78CLZDihydrofolate reductase1.5.1.30.466
1s1vTNKGag-Pol polyprotein2.7.7.490.466
3qaqQAQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.466
4elf35IDihydrofolate reductase/0.466
4iui1GQEstrogen receptor/0.466
1fm4DXCMajor pollen allergen Bet v 1-L/0.465
1jlaTNKGag-Pol polyprotein2.7.7.490.465
1ml6GBXGlutathione S-transferase A22.5.1.180.465
1ndzFR5Adenosine deaminase3.5.4.40.465
3sgv2BJDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.465
3sp9IL2Peroxisome proliferator-activated receptor delta/0.465
3vn2TLSPeroxisome proliferator-activated receptor gamma/0.464
4g47TZFMycocyclosin synthase1.14.21.90.464
1s1tUC1Gag-Pol polyprotein2.7.7.490.463
2om9AJAPeroxisome proliferator-activated receptor gamma/0.463
3cd2MTXDihydrofolate reductase1.5.1.30.463
3mnrSD1Heat shock protein HSP 90-alpha/0.463
4b10NHWGlycylpeptide N-tetradecanoyltransferase/0.463
4jvf17XRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.463
1ysx4EBSerum albumin/0.462
2gjnFMNNitronate monooxygenase1.13.12.160.462
2q59240Peroxisome proliferator-activated receptor gamma/0.462
3ctj320Hepatocyte growth factor receptor2.7.10.10.462
3fcoIIGCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.462
3kjsDQ1Bifunctional dihydrofolate reductase-thymidylate synthase/0.462
3mdvCL6Cholesterol 24-hydroxylase/0.462
3nnuEDBMitogen-activated protein kinase 14/0.462
4elb34RDihydrofolate reductase/0.462
4fjz4FJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.462
5ag7MYAGlycylpeptide N-tetradecanoyltransferase/0.462
1osvCHCBile acid receptor/0.461
3e01PZ2Gag-Pol polyprotein2.7.7.490.461
3ml8ML8Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.461
4a7cE46Serine/threonine-protein kinase pim-12.7.11.10.461
4b12NHWGlycylpeptide N-tetradecanoyltransferase/0.461
4cgpMYAGlycylpeptide N-tetradecanoyltransferase/0.461
4dfn0K1Tyrosine-protein kinase SYK2.7.10.20.461
4g310WHEukaryotic translation initiation factor 2-alpha kinase 32.7.11.10.461
4pkl1GHUncharacterized protein/0.461
4qe6JN3Bile acid receptor/0.461
4z44FADFlavin-dependent tryptophan halogenase PrnA1.14.19.90.461
1disBDMDihydrofolate reductase1.5.1.30.460
1fmjRTLRetinol dehydratase/0.460
4ejh0QACytochrome P450 2A131.14.14.10.460
4o4fATPKinase/0.460
4ug7H4BNitric oxide synthase oxygenase1.14.13.1650.460
3uzcT4EAdenosine receptor A2a/0.460
3uzaT4GAdenosine receptor A2a/0.460
2ykeYKEHeat shock protein HSP 90-alpha/0.459
2z4bDC8Estrogen receptor beta/0.459
3cs8BRLPeroxisome proliferator-activated receptor gamma/0.459
3cy3JN5Serine/threonine-protein kinase pim-12.7.11.10.459
3d7kD7KBenzaldehyde lyase/0.459
3kpkFADSulfide-quinone reductase/0.459
3r7cFADFAD-linked sulfhydryl oxidase ALR1.8.3.20.459
3srrQ20Dihydrofolate reductase1.5.1.30.459
3w5tLHPVitamin D3 receptor/0.459
4oj4DIFPeroxisome proliferator-activated receptor gamma/0.459
1a27ESTEstradiol 17-beta-dehydrogenase 11.1.1.620.458
1cx2S58Prostaglandin G/H synthase 21.14.99.10.458
1sqvUHDCytochrome b/0.458
1w2xRCPAcetyl-CoA carboxylase/0.458
3c0i3AMPeripheral plasma membrane protein CASK2.7.11.10.458
3cd57HI3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.340.458
3gwfFADCyclohexanone monooxygenase/0.458
3lfcZ86Mitogen-activated protein kinase 14/0.458
3vspEK8Peroxisome proliferator-activated receptor gamma/0.458
4b13NHWGlycylpeptide N-tetradecanoyltransferase/0.458
4ure1PSCyclohexanol dehydrogenase/0.458
6cp4CAMCamphor 5-monooxygenase1.14.15.10.458
1fkoEFZGag-Pol polyprotein2.7.7.490.457
1ly3COGDihydrofolate reductase1.5.1.30.457
1yinCM3Estrogen receptor/0.457
2fzhDH1Dihydrofolate reductase1.5.1.30.457
2pmdGNPTranslation initiation factor 2 subunit gamma/0.457
3d3eD3ECorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.457
3d78NBBPheromone-binding protein ASP1/0.457
3dxjNE6DNA-directed RNA polymerase subunit beta/0.457
3dxjNE6DNA-directed RNA polymerase subunit beta'/0.457
4a30MYAGlycylpeptide N-tetradecanoyltransferase/0.457
4g2gTDHMycocyclosin synthase1.14.21.90.457
4jib1L6cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.457
5cccDDFDihydrofolate reductase1.5.1.30.457
1qxlFR8Adenosine deaminase3.5.4.40.456
1v79FR7Adenosine deaminase3.5.4.40.456
4fjyFJYPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.456
4flh14KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.456
4iarERM5-hydroxytryptamine receptor 1B/0.456
4klrCHDFerrochelatase, mitochondrial4.99.1.10.456
4oavACP2-5A-dependent ribonuclease3.1.260.456
4ugaQ05Nitric oxide synthase oxygenase1.14.13.1650.456
4wa9AXITyrosine-protein kinase ABL12.7.10.20.456
1fp2HMOIsoflavone-7-O-methyltransferase 82.1.1.1500.455
1pjkANPCasein kinase II subunit alpha2.7.11.10.455
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.455
2xir00JVascular endothelial growth factor receptor 22.7.10.10.455
2xvv9DNSerum albumin/0.455
3byzH11Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.455
3frdDHFDihydrofolate reductase1.5.1.30.455
3kpzZNEVitamin D3 receptor/0.455
3vsoEK1Peroxisome proliferator-activated receptor gamma/0.455
3w1f1O5Dual specificity protein kinase TTK2.7.12.10.455
3wmxNADNAD dependent epimerase/dehydratase/0.455
4ajwVWNPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform2.7.1.1530.455
4bgePYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.455
4dk50KOPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.455
4e37NDPCatalase1.11.1.60.455
4h50NAPBiphenyl dioxygenase ferredoxin reductase subunit/0.455
4jq8KJ8Epidermal growth factor receptor2.7.10.10.455
4jv618FRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.455
5k2aZMAAdenosine receptor A2a/0.455
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.454
2c27ACOMycothiol acetyltransferase2.3.1.1890.454
2gjlFMNNitronate monooxygenase1.13.12.160.454
2vf0F89Thymidylate synthase/0.454
3a3yOBNSodium/potassium-transporting ATPase subunit alpha/0.454
3oezSTIProto-oncogene tyrosine-protein kinase Src2.7.10.20.454
4feu537Aminoglycoside 3'-phosphotransferase AphA1-IAB/0.454
4m11MXMProstaglandin G/H synthase 21.14.99.10.454
5ajqDB8Serine/threonine-protein kinase 102.7.11.10.454
5epeSAHUncharacterized protein/0.454
1umlFR4Adenosine deaminase3.5.4.40.453
1yhsSTUSerine/threonine-protein kinase pim-12.7.11.10.453
1zg32HIIsoflavone 4'-O-methyltransferase/0.453
1zgaHMKIsoflavone 4'-O-methyltransferase/0.453
2hc4VDXVitamin D3 receptor A/0.453
2idzZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.453
3bgqVX2Serine/threonine-protein kinase pim-12.7.11.10.453
3iqfE4MF420-dependent methylenetetrahydromethanopterin dehydrogenase1.5.98.10.453
3s7a684Dihydrofolate reductase1.5.1.30.453
3vbq0F5Serine/threonine-protein kinase pim-12.7.11.10.453
3zvvXAZPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.453
4nc3ERM5-hydroxytryptamine receptor 2B/0.453
4nmbFADBifunctional protein PutA/0.453
4oze24GUDP-3-O-acyl-N-acetylglucosamine deacetylase/0.453
5a27MYAGlycylpeptide N-tetradecanoyltransferase/0.453
5i2hAGIO-methyltransferase family 2/0.453
5uviZMAAdenosine receptor A2a/0.453
5k2dZMAAdenosine receptor A2a/0.453
1xwsBI1Serine/threonine-protein kinase pim-12.7.11.10.452
2q5p241Peroxisome proliferator-activated receptor gamma/0.452
2qmzLDPRibosyldihydronicotinamide dehydrogenase [quinone]/0.452
2yejZZ3Heat shock protein HSP 90-alpha/0.452
3d84NDPDihydrofolate reductase1.5.1.30.452
3w5rLOAVitamin D3 receptor/0.452
4b14NHWGlycylpeptide N-tetradecanoyltransferase/0.452
4f1sF1SPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.452
4fad0TBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.452
4hvb19PPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.452
4i22IREEpidermal growth factor receptor2.7.10.10.452
4iv41GSEstrogen receptor/0.452
4nkvAERSteroid 17-alpha-hydroxylase/17,20 lyase/0.452
4nky3QZSteroid 17-alpha-hydroxylase/17,20 lyase/0.452
4nr42LKCREB-binding protein/0.452
5cvfATPCasein kinase II subunit alpha2.7.11.10.452
4z34ON7Lysophosphatidic acid receptor 1/0.452
1ie4T44Transthyretin/0.451
1p0hACOMycothiol acetyltransferase2.3.1.1890.451
2o65MYFSerine/threonine-protein kinase pim-12.7.11.10.451
2y00Y01Beta-1 adrenergic receptor/0.451
2z97CAMCamphor 5-monooxygenase1.14.15.10.451
3h1jSMACytochrome b/0.451
3nj0PYVAbscisic acid receptor PYL2/0.451
3pxvFMNNitroreductase/0.451
3vtdTKDVitamin D3 receptor/0.451
4e4qRRHPeroxisome proliferator-activated receptor gamma/0.451
4j6dTESCytochrome P450 monooxygenase/0.451
4oa9ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.451
5hi2BAXSerine/threonine-protein kinase B-raf2.7.11.10.451
1diuBDMDihydrofolate reductase1.5.1.30.450
1ia3TQ5Dihydrofolate reductase1.5.1.30.450
1kv2B96Mitogen-activated protein kinase 14/0.450
1lsjNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.450
1p44GEQEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.450
1rrmAPRLactaldehyde reductase1.1.1.770.450
1xddAAYIntegrin alpha-L/0.450
1yi3LY2Serine/threonine-protein kinase pim-12.7.11.10.450
2bx8AZQSerum albumin/0.450
2g2hP16Tyrosine-protein kinase ABL12.7.10.20.450
2hqpNDPDihydrofolate reductase1.5.1.30.450
2ivuZD6Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.450
2zmd537Dual specificity protein kinase TTK2.7.12.10.450
3at4CCKCasein kinase II subunit alpha2.7.11.10.450
3icsADPCoenzyme A disulfide reductase/0.450
3iqzH4MF420-dependent methylenetetrahydromethanopterin dehydrogenase1.5.98.10.450
3lj3WYEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.450
3o4rNAPDehydrogenase/reductase SDR family member 41.1.1.1840.450
3vt5YI2Vitamin D3 receptor/0.450
4ceoG0TIntegrase/0.450
5e8xSTUTGF-beta receptor type-12.7.11.300.450
5kjePFBAlcohol dehydrogenase E chain1.1.1.10.450
1g67TZPThiamine-phosphate synthase/0.449
1kt3RTLRetinol-binding protein 4/0.449
1om1IQACasein kinase II subunit alpha2.7.11.10.449
1wrlTFPTroponin C, slow skeletal and cardiac muscles/0.449
1zeoC01Peroxisome proliferator-activated receptor gamma/0.449
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.449
2q61SF1Peroxisome proliferator-activated receptor gamma/0.449
2uzeC95Cyclin-dependent kinase 22.7.11.220.449
3dokGWJPol protein/0.449
3h0a9RARetinoic acid receptor RXR-alpha/0.449
3jwcEKBDihydrofolate reductase/0.449
3sruQ26Dihydrofolate reductase1.5.1.30.449
3sz0FADSulfide-quinone reductase/0.449
3t3r9PLCytochrome P450 2A61.14.130.449
4anuEM7Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.449
4ewn0VRImidazole glycerol phosphate synthase subunit HisF4.1.30.449
4hle17VPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.449
4iq71G9Mycocyclosin synthase1.14.21.90.449
4ubsDIFPentalenic acid synthase1.14.15.110.449
4ugaH4BNitric oxide synthase oxygenase1.14.13.1650.449
4wdb2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.449
5ikqJMSProstaglandin G/H synthase 21.14.99.10.449
5k2bZMAAdenosine receptor A2a/0.449
1jstATPCyclin-dependent kinase 22.7.11.220.448
1kt6RTLRetinol-binding protein 4/0.448
2g0nGDPRas-related C3 botulinum toxin substrate 3/0.448
2p15EZTEstrogen receptor/0.448
2p4yC03Peroxisome proliferator-activated receptor gamma/0.448
2y7jB49Phosphorylase b kinase gamma catalytic chain, liver/testis isoform2.7.11.190.448
3a4pDFQHepatocyte growth factor receptor2.7.10.10.448
3clbNAPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.448
3dgaNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.448
3fzsB96Protein-tyrosine kinase 2-beta2.7.10.20.448
3gobHXXDdmC/0.448
3h18PMSEsterase/lipase/0.448
3hz142CHeat shock protein HSP 90-alpha/0.448
3inmNDPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.448
3irn1CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.448
3iro2CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.448
3w0yDS4Vitamin D3 receptor/0.448
4b1fKRHGlutamate racemase/0.448
4jazSTLPeroxisome proliferator-activated receptor gamma/0.448
4jsjQJ7Nitric oxide synthase, brain1.14.13.390.448
4k0y1OASerine/threonine-protein kinase pim-12.7.11.10.448
4ykfFADAlkyl hydroperoxide reductase subunit F1.8.10.448
3pwhZMAAdenosine receptor A2a/0.448
3emlZMAAdenosine receptor A2a/0.448
1aoeGW3Dihydrofolate reductase1.5.1.30.447
1g4pFQPThiamine-phosphate synthase/0.447
1rd4L08Integrin alpha-L/0.447
1tw2ERTCarminomycin 4-O-methyltransferase DnrK2.1.1.2920.447
1uycPU7Heat shock protein HSP 90-alpha/0.447
2ewpTXFEstrogen-related receptor gamma/0.447
2j5xGSPADP-ribosylation factor 6/0.447
3apfBMWPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
3bejMUFBile acid receptor/0.447
3bfa9ODOdorant binding protein ASP1/0.447
3hcrCHDFerrochelatase, mitochondrial4.99.1.10.447
3oewNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.447
3s1dZIRCytokinin dehydrogenase 11.5.99.120.447
3stxBKAMethylketone synthase I/0.447
3th8TH9Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.447
4dpdDHFBifunctional dihydrofolate reductase-thymidylate synthase/0.447
4dscA8SAbscisic acid receptor PYL3/0.447
4hfmNAP2-alkenal reductase (NADP(+)-dependent)/0.447
4hw319GInduced myeloid leukemia cell differentiation protein Mcl-1/0.447
4lm5Q17Serine/threonine-protein kinase pim-12.7.11.10.447
4lwaQ13Nitric oxide synthase oxygenase1.14.13.1650.447
4ok1198Androgen receptor/0.447
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.447
1errRALEstrogen receptor/0.446
1kk4ACOStreptogramin A acetyltransferase2.3.10.446
1qnfHDFDeoxyribodipyrimidine photo-lyase4.1.99.30.446
1t1rIMB1-deoxy-D-xylulose 5-phosphate reductoisomerase1.1.1.2670.446
1xqcAEJEstrogen receptor/0.446
2iw84SPCyclin-dependent kinase 22.7.11.220.446
2w3vTOPDihydrofolate reductase/0.446
2xszATPRuvB-like 23.6.4.120.446
2z3uCRRCytochrome P450/0.446
3a60STURibosomal protein S6 kinase beta-12.7.11.10.446
3ar7TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.446
3bgpVX1Serine/threonine-protein kinase pim-12.7.11.10.446
3jxwLXGSerine/threonine-protein kinase pim-12.7.11.10.446
3lalKRVGag-Pol polyprotein2.7.7.490.446
3oafOAGDihydrofolate reductase1.5.1.30.446
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.446
4awo99BHeat shock protein HSP 90-alpha/0.446
4bgq38RCyclin-dependent kinase-like 52.7.11.220.446
4dbzNDPPutative ketoacyl reductase1.3.10.446
4f700STCyclin-dependent kinase 82.7.11.220.446
4g1z0VPVitamin D3 receptor A/0.446
4tv3ML9Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform/0.446
1bvrTHTEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.445
1dz6CAMCamphor 5-monooxygenase1.14.15.10.445
1eh4IC1Casein kinase I homolog 12.7.11.10.445
1kmsLIHDihydrofolate reductase1.5.1.30.445
1kzjCB3Thymidylate synthase/0.445
1s19MC9Vitamin D3 receptor/0.445
1uyhPU0Heat shock protein HSP 90-alpha/0.445
1zdwFLVPrenyltransferase/0.445
2cig1DGDihydrofolate reductase1.5.1.30.445
2hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.445
2puhHPK2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase3.7.1.80.445
2v4lABJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
2yejXQKHeat shock protein HSP 90-alpha/0.445
2zb45OPProstaglandin reductase 21.3.1.480.445
2znnS44Peroxisome proliferator-activated receptor alpha/0.445
3vt65YIVitamin D3 receptor/0.445
4a9e3PFBromodomain-containing protein 2/0.445
4aojV4ZHigh affinity nerve growth factor receptor2.7.10.10.445
4fgh0U6Dihydrofolate reductase1.5.1.30.445
4g6hNAIRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.445
4h9814QUncharacterized protein/0.445
4ia7BIVVitamin D3 receptor A/0.445
4m69ANPReceptor-interacting serine/threonine-protein kinase 32.7.11.10.445
4n702HXSerine/threonine-protein kinase pim-12.7.11.10.445
1f17NAIHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.444
1fpqSAMIsoliquiritigenin 2'-O-methyltransferase/0.444
1lsoNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.444
1m7aMQUDihydrofolate reductase1.5.1.30.444
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.444
1qaxHMG3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.880.444
1qiqACCIsopenicillin N synthase1.21.3.10.444
1sn5T3Transthyretin/0.444
1w83L11Mitogen-activated protein kinase 14/0.444
2b52D42Cyclin-dependent kinase 22.7.11.220.444
2chz093Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
2igyA2TPlasmepsin 2/0.444
2ittAEEEpidermal growth factor receptor2.7.10.10.444
2p1u4TNRetinoic acid receptor RXR-alpha/0.444
2pzpACPFibroblast growth factor receptor 2/0.444
2xizXIZSerine/threonine-protein kinase pim-12.7.11.10.444
2yboSAHMethyltransferase/0.444
2ydvNECAdenosine receptor A2a/0.444
2ykjYKJHeat shock protein HSP 90-alpha/0.444
3d7tSTUTyrosine-protein kinase CSK/0.444
3dhoB2MStreptogramin A acetyltransferase2.3.10.444
3exhTPPPyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial1.2.4.10.444
3exhTPPPyruvate dehydrogenase E1 component subunit beta, mitochondrial1.2.4.10.444
3h0aD30Peroxisome proliferator-activated receptor gamma/0.444
3invNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.444
3oiaA31Camphor 5-monooxygenase1.14.15.10.444
3umxQ18Serine/threonine-protein kinase pim-12.7.11.10.444
3vjhJ35Peroxisome proliferator-activated receptor gamma/0.444
4enhFVXCholesterol 24-hydroxylase/0.444
4eufNADTrans-2-enoyl-CoA reductase [NADH]/0.444
4ez50RSCyclin-dependent kinase 62.7.11.220.444
4h3c0YZDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.444
4l7sG7KTyrosine-protein kinase ITK/TSK2.7.10.20.444
4mfb29TGag-Pol polyprotein2.7.7.490.444
5iubCLRAdenosine receptor A2a/0.444
1a4iNDPC-1-tetrahydrofolate synthase, cytoplasmic1.5.1.50.443
1ao8MTXDihydrofolate reductase1.5.1.30.443
1aqbRTLRetinol-binding protein 4/0.443
1dxoFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.443
1fp1HCCIsoliquiritigenin 2'-O-methyltransferase/0.443
1gii1PUCyclin-dependent kinase 22.7.11.220.443
1hfqMOTDihydrofolate reductase1.5.1.30.443
1hk2T44Serum albumin/0.443
1ndeMONEstrogen receptor beta/0.443
2acwUPGGlycosyltransferase/0.443
2aibERGBeta-elicitin cinnamomin/0.443
2e9cB75Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.443
2jdsL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.443
2pvnP63Casein kinase II subunit alpha2.7.11.10.443
2q9fC3SCholesterol 24-hydroxylase/0.443
2yeiXQIHeat shock protein HSP 90-alpha/0.443
2znq401Peroxisome proliferator-activated receptor delta/0.443
3cseN22Uncharacterized protein/0.443
3e9319BMitogen-activated protein kinase 14/0.443
3m08RARDihydrofolate reductase1.5.1.30.443
3mvl38PMitogen-activated protein kinase 14/0.443
3wgwT2BProliferating cell nuclear antigen/0.443
3zoiM2WIsopenicillin N synthase1.21.3.10.443
4b8zNAPGDP-L-fucose synthase1.1.1.2710.443
4kaoKAOFocal adhesion kinase 12.7.10.20.443
4ug91EWNitric oxide synthase oxygenase1.14.13.1650.443
6coxS58Prostaglandin G/H synthase 21.14.99.10.443
7catNDPCatalase1.11.1.60.443
1e1nFADNADPH:adrenodoxin oxidoreductase, mitochondrial1.18.1.60.442
1ie9VDXVitamin D3 receptor/0.442
1kvkATPMevalonate kinase2.7.1.360.442
1lb9DNQGlutamate receptor 2/0.442
1lcoPPYCytochrome b2, mitochondrial1.1.2.30.442
1lhvNOGSex hormone-binding globulin/0.442
1rc0KT5Trifunctional purine biosynthetic protein adenosine-32.1.2.20.442
1zmdNAIDihydrolipoyl dehydrogenase, mitochondrial1.8.1.40.442
2oyuIMSProstaglandin G/H synthase 11.14.99.10.442
2qo6CHDFatty acid-binding protein 10-A, liver basic/0.442
2yfeYFEPeroxisome proliferator-activated receptor gamma/0.442
3hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.442
4egnTWOCytochrome P450/0.442
4eiyZMAAdenosine receptor A2a/0.442
4gueQCTRibosomal protein S6 kinase alpha-32.7.11.10.442
4iw8KN3Estrogen receptor/0.442
4ktl1CQCytochrome P450/0.442
4lxjLANLanosterol 14-alpha demethylase1.14.13.700.442
4mbl26LSerine/threonine-protein kinase pim-12.7.11.10.442
4mq12C3Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.442
1ia4TQ6Dihydrofolate reductase1.5.1.30.441
1kqwRTLCellular retinol-binding protein type II/0.441
1m79MQ1Dihydrofolate reductase1.5.1.30.441
1qiwDPDCalmodulin/0.441
2g78REACellular retinoic acid-binding protein 2/0.441
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.441
2i4zDRHPeroxisome proliferator-activated receptor gamma/0.441
2nnhREACytochrome P450 2C8/0.441
2qboCAMCamphor 5-monooxygenase1.14.15.10.441
2y98MIVMycinamicin IV hydroxylase/epoxidase/0.441
2ydoADNAdenosine receptor A2a/0.441
3bfb9ODPheromone-binding protein ASP1/0.441
3l08ZIGPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
3lu6IMXSerum albumin/0.441
3nmnPYVAbscisic acid receptor PYL1/0.441
3pe6ZYHMonoglyceride lipase/0.441
3r6pA8SAbscisic acid receptor PYL10/0.441
3s79ASDAromatase1.14.14.140.441
3vrwYS5Vitamin D3 receptor/0.441
4bqpNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.441
4fhh0U3Vitamin D3 receptor A/0.441
4kwi1TJReductase homolog/0.441
4o761M3Bromodomain-containing protein 4/0.441
5c8wPCGcGMP-dependent protein kinase 22.7.11.120.441
5kj1PFBAlcohol dehydrogenase E chain1.1.1.10.441
5iu86DZAdenosine receptor A2a/0.441
1e79ATPATP synthase subunit alpha, mitochondrial/0.440
1e79ATPATP synthase subunit beta, mitochondrial3.6.3.140.440
1fmlRTLRetinol dehydratase/0.440
1t85CAMCamphor 5-monooxygenase1.14.15.10.440
1xdkREARetinoic acid receptor beta/0.440
2aqhNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.440
2azyCHDPhospholipase A2, major isoenzyme3.1.1.40.440
2duv371Cyclin-dependent kinase 22.7.11.220.440
2j2iLY4Serine/threonine-protein kinase pim-12.7.11.10.440
2po7CHDFerrochelatase, mitochondrial4.99.1.10.440
2vu3LZECyclin-dependent kinase 22.7.11.220.440
2w1fL0FAurora kinase A2.7.11.10.440
2xw7NDPDihydrofolate reductase/0.440
3fywXCFDihydrofolate reductase1.5.1.30.440
3iaeD7KBenzaldehyde lyase/0.440
3kq7KQ7Mitogen-activated protein kinase 14/0.440
3nwlNDPCatalase1.11.1.60.440
3nx4NAPPutative oxidoreductase/0.440
3qlwN22Dihydrofolate reductase1.5.1.30.440
3vt7VDXVitamin D3 receptor/0.440
4dtiNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.440
4eo80S3Genome polyprotein2.7.7.480.440
4fhi0S4Vitamin D3 receptor A/0.440
4i8vBHFCytochrome P450 1A11.14.14.10.440
4iwc1GVEstrogen receptor/0.440
4kfbT27Gag-Pol polyprotein2.7.7.490.440
4pd6URINucleoside permease/0.440
5a3cNADSIR2 family protein/0.440
5ai5BSUBifunctional epoxide hydrolase 23.1.3.760.440
3reyXACAdenosine receptor A2a/0.440
3rfmCFFAdenosine receptor A2a/0.440