sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1qy5 | NEC | Endoplasmin |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 1qy5 | NEC | Endoplasmin | / | 1.000 | |
| 1qy8 | RDI | Endoplasmin | / | 0.686 | |
| 1u0y | PA7 | Endoplasmin | / | 0.598 | |
| 2yeg | XQG | Heat shock protein HSP 90-alpha | / | 0.569 | |
| 3wha | WHA | Heat shock protein HSP 90-alpha | / | 0.565 | |
| 3hhu | 819 | Heat shock protein HSP 90-alpha | / | 0.562 | |
| 2gfd | RDA | Endoplasmin | / | 0.560 | |
| 2fyp | RDE | Endoplasmin | / | 0.559 | |
| 2gqp | PA7 | Endoplasmin | / | 0.554 | |
| 2bz5 | AB4 | Heat shock protein HSP 90-alpha | / | 0.551 | |
| 3b28 | B2X | Heat shock protein HSP 90-alpha | / | 0.551 | |
| 2hg1 | N5O | Endoplasmin | / | 0.546 | |
| 2xab | VHD | Heat shock protein HSP 90-alpha | / | 0.545 | |
| 3hek | BD0 | Heat shock protein HSP 90-alpha | / | 0.544 | |
| 3eko | PYU | Heat shock protein HSP 90-alpha | / | 0.543 | |
| 3ekr | PY9 | Heat shock protein HSP 90-alpha | / | 0.542 | |
| 1u2o | NEC | Endoplasmin | / | 0.538 | |
| 3rlr | 3RR | Heat shock protein HSP 90-alpha | / | 0.536 | |
| 1u0z | RDC | Endoplasmin | / | 0.533 | |
| 2wi6 | ZZ6 | Heat shock protein HSP 90-alpha | / | 0.532 | |
| 4bqj | XKL | Heat shock protein HSP 90-alpha | / | 0.531 | |
| 3rlq | 3RQ | Heat shock protein HSP 90-alpha | / | 0.528 | |
| 3r4p | FU7 | Heat shock protein HSP 90-alpha | / | 0.527 | |
| 2bt0 | CT5 | Heat shock protein HSP 90-alpha | / | 0.526 | |
| 3hyz | 42C | Heat shock protein HSP 90-alpha | / | 0.520 | |
| 4fcr | 0TM | Heat shock protein HSP 90-alpha | / | 0.520 | |
| 1uyh | PU0 | Heat shock protein HSP 90-alpha | / | 0.519 | |
| 2wer | RDC | ATP-dependent molecular chaperone HSP82 | / | 0.519 | |
| 2hch | N5A | Endoplasmin | / | 0.516 | |
| 1yc4 | 43P | Heat shock protein HSP 90-alpha | / | 0.514 | |
| 1ysz | NEC | Endoplasmin | / | 0.514 | |
| 4eag | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.511 | |
| 1uy8 | PU5 | Heat shock protein HSP 90-alpha | / | 0.510 | |
| 1yc1 | 4BC | Heat shock protein HSP 90-alpha | / | 0.507 | |
| 2xhr | C0P | Heat shock protein HSP 90-alpha | / | 0.506 | |
| 1uy7 | PU4 | Heat shock protein HSP 90-alpha | / | 0.505 | |
| 2qg0 | A94 | Heat shock protein HSP 90-alpha | / | 0.504 | |
| 2xd6 | XD6 | ATP-dependent molecular chaperone HSP82 | / | 0.504 | |
| 3k99 | PFT | Heat shock protein HSP 90-alpha | / | 0.502 | |
| 3k98 | 1RC | Heat shock protein HSP 90-alpha | / | 0.499 | |
| 3r4n | FU5 | Heat shock protein HSP 90-alpha | / | 0.499 | |
| 4ce3 | L4V | ATP-dependent molecular chaperone HSP82 | / | 0.499 | |
| 2qfo | A13 | Heat shock protein HSP 90-alpha | / | 0.496 | |
| 5f5r | ANP | Heat shock protein 75 kDa, mitochondrial | / | 0.496 | |
| 1uy6 | PU3 | Heat shock protein HSP 90-alpha | / | 0.493 | |
| 2iwx | M1S | ATP-dependent molecular chaperone HSP82 | / | 0.492 | |
| 4asg | 814 | ATP-dependent molecular chaperone HSP82 | / | 0.490 | |
| 3k97 | 4CD | Heat shock protein HSP 90-alpha | / | 0.488 | |
| 2f4b | EHA | Peroxisome proliferator-activated receptor gamma | / | 0.487 | |
| 3t2s | AGS | Heat shock protein HSP 90-alpha | / | 0.486 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.485 | |
| 1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.485 | |
| 2fwy | H64 | Heat shock protein HSP 90-alpha | / | 0.484 | |
| 2qfo | A51 | Heat shock protein HSP 90-alpha | / | 0.481 | |
| 1uyc | PU7 | Heat shock protein HSP 90-alpha | / | 0.480 | |
| 2bre | KJ2 | ATP-dependent molecular chaperone HSP82 | / | 0.480 | |
| 2wep | ADP | ATP-dependent molecular chaperone HSP82 | / | 0.480 | |
| 1beu | IPL | Tryptophan synthase alpha chain | / | 0.479 | |
| 1uy9 | PU6 | Heat shock protein HSP 90-alpha | / | 0.476 | |
| 2xx2 | 13C | ATP-dependent molecular chaperone HSP82 | / | 0.476 | |
| 3t1k | ANP | Heat shock protein HSP 90-alpha | / | 0.476 | |
| 3t10 | ACP | Heat shock protein HSP 90-alpha | / | 0.475 | |
| 4ce1 | 7FK | ATP-dependent molecular chaperone HSP82 | / | 0.475 | |
| 2iwu | NP5 | ATP-dependent molecular chaperone HSP82 | / | 0.474 | |
| 4xc0 | ACP | Heat shock cognate 90 kDa protein | / | 0.474 | |
| 1byq | ADP | Heat shock protein HSP 90-alpha | / | 0.473 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.473 | |
| 3omu | IBD | Heat shock protein 83 | / | 0.473 | |
| 4gqt | ADP | Heat shock protein 90 | / | 0.473 | |
| 1bim | 0QB | Renin | 3.4.23.15 | 0.472 | |
| 2iws | NP4 | ATP-dependent molecular chaperone HSP82 | / | 0.472 | |
| 2yei | XQI | Heat shock protein HSP 90-alpha | / | 0.472 | |
| 1bgq | RDC | ATP-dependent molecular chaperone HSP82 | / | 0.471 | |
| 4ce2 | BO5 | ATP-dependent molecular chaperone HSP82 | / | 0.471 | |
| 3v1y | NAD | Glyceraldehyde-3-phosphate dehydrogenase 1, cytosolic | 1.2.1.12 | 0.470 | |
| 1fxs | NAP | GDP-L-fucose synthase | / | 0.468 | |
| 1uyi | PUZ | Heat shock protein HSP 90-alpha | / | 0.468 | |
| 2a7r | 5GP | GMP reductase 2 | / | 0.468 | |
| 2wns | OMP | Uridine 5'-monophosphate synthase | 2.4.2.10 | 0.468 | |
| 2brc | CT5 | ATP-dependent molecular chaperone HSP82 | / | 0.467 | |
| 3ied | AN2 | HSP90 | / | 0.467 | |
| 2bu8 | ADP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial | 2.7.11.2 | 0.466 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.466 | |
| 4xcj | ADP | Heat shock cognate 90 kDa protein | / | 0.466 | |
| 2xk2 | ADP | Heat shock protein HSP 90-alpha | / | 0.465 | |
| 3hz5 | Z64 | Heat shock protein HSP 90-alpha | / | 0.465 | |
| 3vha | VHA | Heat shock protein HSP 90-alpha | / | 0.465 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.465 | |
| 4uwm | FMN | 3,6-diketocamphane 1,6 monooxygenase | 1.14.13 | 0.465 | |
| 1am1 | ADP | ATP-dependent molecular chaperone HSP82 | / | 0.464 | |
| 1dhr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.464 | |
| 1dir | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.464 | |
| 2xjx | XJX | Heat shock protein HSP 90-alpha | / | 0.464 | |
| 3hz1 | 42C | Heat shock protein HSP 90-alpha | / | 0.464 | |
| 4b78 | KGG | Beta-secretase 1 | 3.4.23.46 | 0.464 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.464 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.464 | |
| 1pjc | NAD | Alanine dehydrogenase | / | 0.463 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
| 1nvt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.462 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.462 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.462 | |
| 3q5k | D1U | Heat shock protein 83-1 | / | 0.461 | |
| 4jql | VJ6 | Heat shock protein HSP 90-alpha | / | 0.461 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.461 | |
| 1diu | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.460 | |
| 3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.460 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.459 | |
| 1y4s | ADP | Chaperone protein HtpG | / | 0.459 | |
| 2xcm | ADP | Cytosolic heat shock protein 90 | / | 0.459 | |
| 3b6z | CO7 | Enoyl reductase LovC | 1 | 0.459 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.459 | |
| 2bri | ANP | Uridylate kinase | 2.7.4.22 | 0.458 | |
| 2dte | NAI | Glucose 1-dehydrogenase related protein | / | 0.458 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.458 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.458 | |
| 3a3b | RBF | Lumazine protein | / | 0.458 | |
| 3c11 | GDM | ATP-dependent molecular chaperone HSP82 | / | 0.458 | |
| 3gob | HXX | DdmC | / | 0.458 | |
| 4do0 | DZA | Histone lysine demethylase PHF8 | 1.14.11.27 | 0.458 | |
| 4p8r | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.458 | |
| 5hs1 | VOR | Lanosterol 14-alpha demethylase | / | 0.458 | |
| 1kor | ANP | Argininosuccinate synthase | / | 0.457 | |
| 2byh | 2D7 | Heat shock protein HSP 90-alpha | / | 0.457 | |
| 2c27 | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.457 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.457 | |
| 2wi5 | ZZ5 | Heat shock protein HSP 90-alpha | / | 0.457 | |
| 3kb1 | ADP | Iron-sulfur cluster carrier protein | / | 0.457 | |
| 4awp | 99A | Heat shock protein HSP 90-alpha | / | 0.457 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.457 | |
| 1nuu | NAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.456 | |
| 1txt | CAA | HMG-CoA synthase | / | 0.456 | |
| 2brb | PFQ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.456 | |
| 2brm | DFZ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.456 | |
| 2ggs | NDP | dTDP-4-dehydrorhamnose reductase | / | 0.456 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.456 | |
| 2xht | C0Y | Heat shock protein HSP 90-alpha | / | 0.456 | |
| 3crl | ANP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial | 2.7.11.2 | 0.456 | |
| 3lpi | Z74 | Beta-secretase 1 | 3.4.23.46 | 0.456 | |
| 5fwn | NAP | Putative dehydrogenase | / | 0.456 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.455 | |
| 3b70 | NAP | Enoyl reductase LovC | 1 | 0.455 | |
| 3sj7 | NDP | 3-oxoacyl-(Acyl-carrier-protein) reductase, putative | / | 0.455 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.455 | |
| 5itz | LOC | Tubulin beta-2B chain | / | 0.455 | |
| 2qbl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.454 | |
| 2rh9 | IGP | Tryptophan synthase alpha chain | / | 0.454 | |
| 2wsb | NAD | Galactitol dehydrogenase | / | 0.454 | |
| 2z54 | AB1 | Gag-Pol polyprotein | 3.4.23.16 | 0.454 | |
| 3i2l | 2NC | Protease | / | 0.454 | |
| 3qls | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 4b77 | 54M | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.454 | |
| 4q72 | FAD | Bifunctional protein PutA | / | 0.454 | |
| 1ia1 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.453 | |
| 2clq | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.453 | |
| 3zw9 | NAD | Peroxisomal bifunctional enzyme | 1.1.1.35 | 0.453 | |
| 4eft | EFT | Heat shock protein HSP 90-alpha | / | 0.453 | |
| 5d3q | GDP | Dynamin-1 | 3.6.5.5 | 0.453 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.452 | |
| 2hfu | MEV | Mevalonate kinase | / | 0.452 | |
| 2zdy | ADP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial | 2.7.11.2 | 0.452 | |
| 3cib | 314 | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.452 | |
| 3gfb | NAD | L-threonine 3-dehydrogenase | / | 0.452 | |
| 3t0z | ATP | Heat shock protein HSP 90-alpha | / | 0.452 | |
| 4c3f | 7KW | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.452 | |
| 4kug | NAD | 3-hydroxybutyryl-CoA dehydrogenase | / | 0.452 | |
| 1npd | NAD | Quinate/shikimate dehydrogenase | / | 0.451 | |
| 1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.451 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.451 | |
| 3img | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.451 | |
| 4bii | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.451 | |
| 4mih | FAD | Pyranose 2-oxidase | 1.1.3.10 | 0.451 | |
| 5bsg | NAP | Pyrroline-5-carboxylate reductase | / | 0.451 | |
| 1hyg | NAP | L-2-hydroxycarboxylate dehydrogenase (NAD(P)(+)) | / | 0.450 | |
| 1tqf | 32P | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 2fde | 385 | Gag-Pol polyprotein | 3.4.23.16 | 0.450 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.450 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.450 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.450 | |
| 3ids | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.450 | |
| 3slz | 3TL | Putative gag-pro-pol polyprotein | / | 0.450 | |
| 4a61 | ANP | Plasmid segregation protein ParM | / | 0.450 | |
| 4dre | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.450 | |
| 4g74 | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.450 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.450 | |
| 4rlh | 0WE | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.450 | |
| 1dyj | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1ep1 | FMN | Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit | 1.3.1.14 | 0.449 | |
| 1icp | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.449 | |
| 1kfb | IGP | Tryptophan synthase alpha chain | / | 0.449 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.449 | |
| 2b4r | AES | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.449 | |
| 2yi5 | YI5 | Heat shock protein HSP 90-alpha | / | 0.449 | |
| 3d0b | SNX | Heat shock protein HSP 90-alpha | / | 0.449 | |
| 3inv | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.449 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.449 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.449 | |
| 4eji | 0QA | Cytochrome P450 2A13 | 1.14.14.1 | 0.449 | |
| 4fv6 | E57 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.449 | |
| 4hbm | 0Y7 | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.449 | |
| 5ein | NAP | [LysW]-L-2-aminoadipate 6-phosphate reductase | / | 0.449 | |
| 1ra3 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1ra8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1t7i | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.448 | |
| 2i4j | DRJ | Peroxisome proliferator-activated receptor gamma | / | 0.448 | |
| 2qhc | AB1 | Protease | / | 0.448 | |
| 2yef | ANP | Heat shock protein HSP 90-alpha | / | 0.448 | |
| 3oib | FDA | Putative acyl-CoA dehydrogenase | / | 0.448 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.448 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.448 | |
| 4ktk | KTK | Cytochrome P450 | / | 0.448 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.448 | |
| 4rrv | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.448 | |
| 5a9s | NAP | Putative dehydrogenase | / | 0.448 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.447 | |
| 1gco | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.447 | |
| 1udb | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.447 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.447 | |
| 2dfv | NAD | L-threonine 3-dehydrogenase | / | 0.447 | |
| 2gmh | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.447 | |
| 2wi4 | ZZ4 | Heat shock protein HSP 90-alpha | / | 0.447 | |
| 3amf | FMN | FMN-binding protein | / | 0.447 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.447 | |
| 3m1v | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.447 | |
| 3m1v | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.447 | |
| 3r3s | NAD | Putative oxidoreductase | / | 0.447 | |
| 3t4n | ADP | 5'-AMP-activated protein kinase subunit gamma | / | 0.447 | |
| 4dd8 | BAT | Disintegrin and metalloproteinase domain-containing protein 8 | 3.4.24 | 0.447 | |
| 4g2g | TDH | Mycocyclosin synthase | 1.14.21.9 | 0.447 | |
| 4g47 | TZF | Mycocyclosin synthase | 1.14.21.9 | 0.447 | |
| 4h3j | 10W | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 4l7f | 1V5 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.447 | |
| 4y93 | 746 | Tyrosine-protein kinase | / | 0.447 | |
| 4zow | CLM | Multidrug transporter MdfA | / | 0.447 | |
| 1ay0 | TPP | Transketolase 1 | 2.2.1.1 | 0.446 | |
| 1h73 | ANP | Homoserine kinase | 2.7.1.39 | 0.446 | |
| 1mja | COA | Histone acetyltransferase ESA1 | / | 0.446 | |
| 1yc3 | 4BC | Heat shock protein HSP 90-alpha | / | 0.446 | |
| 2dsh | SAH | Diphthine synthase | / | 0.446 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.446 | |
| 2i4p | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.446 | |
| 2qa2 | FAD | Polyketide oxygenase CabE | / | 0.446 | |
| 3a6r | FMN | FMN-binding protein | / | 0.446 | |
| 3fhy | ATP | Pyridoxal kinase | 2.7.1.35 | 0.446 | |
| 3h3c | P1E | Protein-tyrosine kinase 2-beta | 2.7.10.2 | 0.446 | |
| 3hll | I45 | Mitogen-activated protein kinase 14 | / | 0.446 | |
| 3hwr | NDP | 2-dehydropantoate 2-reductase | / | 0.446 | |
| 3ieu | GDP | GTPase Era | / | 0.446 | |
| 3jun | AKD | Phenazine biosynthesis protein A/B | / | 0.446 | |
| 3wrj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 3wrm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.446 | |
| 4i6g | FAD | Cryptochrome-2 | / | 0.446 | |
| 4ms1 | 381 | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.446 | |
| 4qec | NAP | ElxO | / | 0.446 | |
| 4qi5 | FAD | Cellobiose dehydrogenase | / | 0.446 | |
| 4yag | NAI | C alpha-dehydrogenase | / | 0.446 | |
| 1bsv | NDP | GDP-L-fucose synthase | / | 0.445 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.445 | |
| 1k7l | 544 | Peroxisome proliferator-activated receptor alpha | / | 0.445 | |
| 1rx1 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 2p8u | COA | Hydroxymethylglutaryl-CoA synthase, cytoplasmic | 2.3.3.10 | 0.445 | |
| 2yxu | ATP | Pyridoxal kinase | 2.7.1.35 | 0.445 | |
| 2znn | S44 | Peroxisome proliferator-activated receptor alpha | / | 0.445 | |
| 3dm6 | 757 | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 3k4n | FAD | Pyranose 2-oxidase | / | 0.445 | |
| 3rai | X85 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.445 | |
| 3tnl | NAD | Shikimate dehydrogenase (NADP(+)) | / | 0.445 | |
| 4as9 | 4QS | ATP-dependent molecular chaperone HSP82 | / | 0.445 | |
| 4rv9 | SAH | D-mycarose 3-C-methyltransferase | / | 0.445 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.444 | |
| 1h74 | AGS | Homoserine kinase | 2.7.1.39 | 0.444 | |
| 1jol | FFO | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 2ag5 | NAD | 3-hydroxybutyrate dehydrogenase type 2 | / | 0.444 | |
| 2c3k | ABO | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
| 2e9o | A58 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
| 2i4x | KGQ | Protease | / | 0.444 | |
| 2rcy | NAP | Pyrroline-5-carboxylate reductase | / | 0.444 | |
| 3d2r | ADP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial | 2.7.11.2 | 0.444 | |
| 3jus | BCD | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.444 | |
| 3rpe | FAD | Putative modulator of drug activity | / | 0.444 | |
| 3upf | 0BU | Polyprotein | / | 0.444 | |
| 3vyd | VYD | Renin | 3.4.23.15 | 0.444 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 4bc7 | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.444 | |
| 4c34 | STU | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.444 | |
| 4g48 | PZB | Mycocyclosin synthase | 1.14.21.9 | 0.444 | |
| 4i8z | G08 | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 4ktl | 1CQ | Cytochrome P450 | / | 0.444 | |
| 4l4x | NDP | AmphI | / | 0.444 | |
| 5bsf | NAD | Pyrroline-5-carboxylate reductase | / | 0.444 | |
| 1ai9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1guy | NAD | Malate dehydrogenase | / | 0.443 | |
| 1ywg | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.443 | |
| 2ewm | NAD | (S)-1-Phenylethanol dehydrogenase | 1.1.1.311 | 0.443 | |
| 2vwq | NAP | Glucose 1-dehydrogenase | / | 0.443 | |
| 2xa4 | AZ5 | Tyrosine-protein kinase JAK2 | / | 0.443 | |
| 2zui | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 3fwg | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 3jyp | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.443 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.443 | |
| 3nu9 | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.443 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 4hbg | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.443 | |
| 4ips | 1G4 | Mycocyclosin synthase | 1.14.21.9 | 0.443 | |
| 4kgm | ATP | Uncharacterized protein | / | 0.443 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.443 | |
| 4ylf | FAD | Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit homolog | / | 0.443 | |
| 1bxk | NAD | dTDP-glucose 4,6-dehydratase 2 | / | 0.442 | |
| 1h74 | ADP | Homoserine kinase | 2.7.1.39 | 0.442 | |
| 1lrj | UD1 | UDP-glucose 4-epimerase | 5.1.3.2 | 0.442 | |
| 1msn | JE2 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 1nzf | UPG | DNA beta-glucosyltransferase | / | 0.442 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.442 | |
| 1vi2 | NAD | Quinate/shikimate dehydrogenase | / | 0.442 | |
| 1yrc | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 2dft | ADP | Shikimate kinase | 2.7.1.71 | 0.442 | |
| 2fxs | RDA | ATP-dependent molecular chaperone HSP82 | / | 0.442 | |
| 2q8s | L92 | Peroxisome proliferator-activated receptor gamma | / | 0.442 | |
| 2rhg | IGP | Tryptophan synthase alpha chain | / | 0.442 | |
| 2wmr | ZYR | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
| 3iqh | TYR_ASP_ILE | Cysteine synthase | 2.5.1.47 | 0.442 | |
| 3opd | HIE | Heat shock protein 83 | / | 0.442 | |
| 3te5 | NAI | 5'-AMP-activated protein kinase subunit gamma | / | 0.442 | |
| 3tsc | NAD | Uncharacterized protein | / | 0.442 | |
| 4acx | S8Z | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 4b00 | I6X | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 4ew3 | DXZ | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.442 | |
| 4l4d | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 4rcv | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.442 | |
| 1amw | ADP | ATP-dependent molecular chaperone HSP82 | / | 0.441 | |
| 1hbv | GAN | Gag-Pol polyprotein | / | 0.441 | |
| 1iwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 1ra3 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1rdt | 570 | Peroxisome proliferator-activated receptor gamma | / | 0.441 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 2byi | 2DD | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 2gqt | FAD | UDP-N-acetylenolpyruvoylglucosamine reductase | / | 0.441 | |
| 2p83 | MR0 | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 2pob | GW4 | Peroxisome proliferator-activated receptor gamma | / | 0.441 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.441 | |
| 2yq9 | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.441 | |
| 3fwf | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 3lpj | Z75 | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 3pej | BC2 | Endoplasmin homolog, putative | / | 0.441 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.441 | |
| 3r4o | FU3 | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 3to6 | LYS_CMC | Histone acetyltransferase ESA1 | / | 0.441 | |
| 3vdq | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.441 | |
| 3wrh | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 4a6c | QG9 | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 4xcl | AGS | Heat shock cognate 90 kDa protein | / | 0.441 | |
| 5hws | NAP | 2-dehydropantoate 2-reductase | / | 0.441 | |
| 1fm9 | 570 | Peroxisome proliferator-activated receptor gamma | / | 0.440 | |
| 1j49 | NAD | D-lactate dehydrogenase | 1.1.1.28 | 0.440 | |
| 1t86 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 1u8v | FAD | 4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase | / | 0.440 | |
| 2gjn | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.440 | |
| 3gqv | NAP | Enoyl reductase LovC | 1 | 0.440 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.440 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.440 | |
| 3t3c | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 3vqh | IQB | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.440 | |
| 4dh6 | 0KN | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 4egb | NAD | dTDP-glucose 4,6-dehydratase | / | 0.440 | |
| 4gav | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.440 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.440 | |
| 4l6g | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.440 | |
| 5dp2 | NAP | CurF | / | 0.440 |