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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1i8zINLCarbonic anhydrase 24.2.1.1

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity
Align
1i8zINLCarbonic anhydrase 24.2.1.11.000
1bn1AL5Carbonic anhydrase 24.2.1.10.818
1zsbAZMCarbonic anhydrase 24.2.1.10.791
3po6DT9Carbonic anhydrase 24.2.1.10.791
2wehFB1Carbonic anhydrase 24.2.1.10.773
3s8xE59Carbonic anhydrase 24.2.1.10.761
3saxE50Carbonic anhydrase 24.2.1.10.756
3eft3BSCarbonic anhydrase 24.2.1.10.748
3mhlJ71Carbonic anhydrase 24.2.1.10.747
1if6FBUCarbonic anhydrase 24.2.1.10.746
1bnnAL1Carbonic anhydrase 24.2.1.10.739
2eu3FF3Carbonic anhydrase 24.2.1.10.738
3m98E02Carbonic anhydrase 24.2.1.10.733
3t84SG6Carbonic anhydrase 24.2.1.10.732
1i91INQCarbonic anhydrase 24.2.1.10.730
3d9zD9ZCarbonic anhydrase 24.2.1.10.730
3oimVZ5Carbonic anhydrase 24.2.1.10.730
3m96E38Carbonic anhydrase 24.2.1.10.729
2h15B19Carbonic anhydrase 24.2.1.10.719
3b4fTUOCarbonic anhydrase 24.2.1.10.719
1bnmAL8Carbonic anhydrase 24.2.1.10.715
3dd82C7Carbonic anhydrase 24.2.1.10.714
4kniE1ECarbonic anhydrase 24.2.1.10.714
4itp1GDCarbonic anhydrase 24.2.1.10.711
1if4FBSCarbonic anhydrase 24.2.1.10.710
2wegFBVCarbonic anhydrase 24.2.1.10.710
1i90INMCarbonic anhydrase 24.2.1.10.705
3ffpLC1Carbonic anhydrase 24.2.1.10.700
3sbhE65Carbonic anhydrase 24.2.1.10.700
3m2yBE0Carbonic anhydrase 24.2.1.10.698
3myqE27Carbonic anhydrase 24.2.1.10.695
3dazMZMCarbonic anhydrase 24.2.1.10.694
3m67E36Carbonic anhydrase 24.2.1.10.693
5fltVJJCarbonic anhydrase 24.2.1.10.687
1g1dFSBCarbonic anhydrase 24.2.1.10.686
3k2fNKXCarbonic anhydrase 24.2.1.10.686
4n16CHDCarbonic anhydrase 24.2.1.10.686
3hkuTORCarbonic anhydrase 24.2.1.10.683
3m2nJ74Carbonic anhydrase 24.2.1.10.683
1ttm667Carbonic anhydrase 24.2.1.10.682
1g52F2BCarbonic anhydrase 24.2.1.10.681
3m40J45Carbonic anhydrase 24.2.1.10.680
3dc3AZMCarbonic anhydrase 24.2.1.10.679
1a42BZUCarbonic anhydrase 24.2.1.10.678
1bn4AL9Carbonic anhydrase 24.2.1.10.678
3mnaDWHCarbonic anhydrase 24.2.1.10.678
1bn3AL6Carbonic anhydrase 24.2.1.10.675
1g4jFFBCarbonic anhydrase 24.2.1.10.674
1i9nIOACarbonic anhydrase 24.2.1.10.674
2x7tWZBCarbonic anhydrase 24.2.1.10.674
3mhoJ43Carbonic anhydrase 24.2.1.10.673
1g54FFBCarbonic anhydrase 24.2.1.10.672
3ni5C1HCarbonic anhydrase 24.2.1.10.672
1bnvAL7Carbonic anhydrase 24.2.1.10.670
3nb5R21Carbonic anhydrase 24.2.1.10.668
3igpDT7Carbonic anhydrase 24.2.1.10.667
3t82SG4Carbonic anhydrase 24.2.1.10.665
3m5eJDRCarbonic anhydrase 24.2.1.10.659
4pxxCHDCarbonic anhydrase 24.2.1.10.659
1kwrSG2Carbonic anhydrase 24.2.1.10.658
1xpz4TZCarbonic anhydrase 24.2.1.10.658
3kigDA4Carbonic anhydrase 24.2.1.10.658
4knjE1FCarbonic anhydrase 24.2.1.10.658
1bntAL2Carbonic anhydrase 24.2.1.10.657
1okmSABCarbonic anhydrase 24.2.1.10.655
3mmfD9HCarbonic anhydrase 24.2.1.10.655
4itoMPXCarbonic anhydrase 24.2.1.10.654
1cnyEG3Carbonic anhydrase 24.2.1.10.651
3mhiJ90Carbonic anhydrase 24.2.1.10.648
1oklMNSCarbonic anhydrase 24.2.1.10.647
1i9pIOECarbonic anhydrase 24.2.1.10.645
1bnwTPDCarbonic anhydrase 24.2.1.10.643
1oknSTBCarbonic anhydrase 24.2.1.10.643
4mo82VQCarbonic anhydrase 24.2.1.10.643
4ilx1EZCarbonic anhydrase 24.2.1.10.640
4iwz1GOCarbonic anhydrase 24.2.1.10.640
3oysOYSCarbonic anhydrase 24.2.1.10.638
3s9tE49Carbonic anhydrase 24.2.1.10.638
4kap1QVCarbonic anhydrase 24.2.1.10.635
3mzcS6ICarbonic anhydrase 24.2.1.10.634
3n0nP9BCarbonic anhydrase 24.2.1.10.633
3ml2SU0Carbonic anhydrase 24.2.1.10.632
3dd0EZLCarbonic anhydrase 24.2.1.10.631
3d8wD8WCarbonic anhydrase 24.2.1.10.630
3qykIE2Carbonic anhydrase 24.2.1.10.630
3sbiE90Carbonic anhydrase 24.2.1.10.628
1xq04TRCarbonic anhydrase 24.2.1.10.627
1i9mINWCarbonic anhydrase 24.2.1.10.624
3n3jWWVCarbonic anhydrase 24.2.1.10.623
3n4bWWZCarbonic anhydrase 24.2.1.10.623
3oikWZBCarbonic anhydrase 24.2.1.10.623
3betCTFCarbonic anhydrase 24.2.1.10.621
3n2pAYXCarbonic anhydrase 24.2.1.10.618
2wejFB2Carbonic anhydrase 24.2.1.10.617
3oy0OY0Carbonic anhydrase 24.2.1.10.614
2powI7CCarbonic anhydrase 24.2.1.10.611
1kwqSG1Carbonic anhydrase 24.2.1.10.610
1i9qIOFCarbonic anhydrase 24.2.1.10.609
2h4nAZMCarbonic anhydrase 24.2.1.10.609
3f4xKLTCarbonic anhydrase 24.2.1.10.609
2wd2MS5Carbonic anhydrase 24.2.1.10.606
2weoFBWCarbonic anhydrase 24.2.1.10.605
4bf6X0QCarbonic anhydrase 24.2.1.10.605
1oq5CELCarbonic anhydrase 24.2.1.10.599
3dccD9ZCarbonic anhydrase 24.2.1.10.598
1cilETSCarbonic anhydrase 24.2.1.10.597
4m2rBZ1Carbonic anhydrase 24.2.1.10.593
4bf19FKCarbonic anhydrase 24.2.1.10.591
4k13ETSCarbonic anhydrase 24.2.1.10.589
1bnqAL4Carbonic anhydrase 24.2.1.10.586
3mdzEZLCarbonic anhydrase 74.2.1.10.584
2x7uWZACarbonic anhydrase 24.2.1.10.583
4kp8E1GCarbonic anhydrase 124.2.1.10.582
1if7SBRCarbonic anhydrase 24.2.1.10.581
3p5lIT5Carbonic anhydrase 24.2.1.10.578
3t85SG7Carbonic anhydrase 24.2.1.10.574
4ht2V50Carbonic anhydrase 124.2.1.10.573
3dcsMZMCarbonic anhydrase 24.2.1.10.572
3dcwEZLCarbonic anhydrase 24.2.1.10.571
3bl1BL1Carbonic anhydrase 24.2.1.10.570
1jd0AZMCarbonic anhydrase 124.2.1.10.566
3oyqOYQCarbonic anhydrase 24.2.1.10.563
3zncBZ1Carbonic anhydrase 44.2.1.10.563
3rz8RZ8Carbonic anhydrase 24.2.1.10.562
3mhcARZCarbonic anhydrase 24.2.1.10.560
1cnwEG1Carbonic anhydrase 24.2.1.10.558
3v2jAZMCarbonic anhydrase 24.2.1.10.556
1if5FBTCarbonic anhydrase 24.2.1.10.552
3dbuD8WCarbonic anhydrase 24.2.1.10.551
1bnuAL3Carbonic anhydrase 24.2.1.10.550
4lu3AZMCarbonic anhydrase 144.2.1.10.550
2q1qOSPCarbonic anhydrase 24.2.1.10.549
1cnxEG2Carbonic anhydrase 24.2.1.10.543
1g45FSBCarbonic anhydrase 24.2.1.10.543
3f7bAG5Carbonic anhydrase 44.2.1.10.543
4kp5E1FCarbonic anhydrase 124.2.1.10.542
3f7uAG4Carbonic anhydrase 44.2.1.10.539
1eouSMSCarbonic anhydrase 24.2.1.10.538
4knmE1ECarbonic anhydrase 134.2.1.10.536
1g4oBSBCarbonic anhydrase 24.2.1.10.535
4hu1V13Carbonic anhydrase 134.2.1.10.535
4k0zMZMCarbonic anhydrase 24.2.1.10.534
1rj6AZMCarbonic anhydrase 144.2.1.10.527
3l14I7BCarbonic anhydrase 24.2.1.10.524
4m2vBZ1Carbonic anhydrase 24.2.1.10.522
3fw3ETSCarbonic anhydrase 44.2.1.10.519
4dz7D02Carbonic anhydrase 24.2.1.10.519
4x5sAZMCarbonic anhydrase (Carbonate dehydratase)/0.515
2q7oIMHPurine nucleoside phosphorylase2.4.2.10.513
4knnE1FCarbonic anhydrase 134.2.1.10.513
1if8SBSCarbonic anhydrase 24.2.1.10.512
1ydaAZMCarbonic anhydrase 24.2.1.10.511
3fhxPLPPyridoxal kinase2.7.1.350.505
2o1sTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.497
2qimZEAClass 10 plant pathogenesis-related protein/0.493
3lxeTORCarbonic anhydrase 14.2.1.10.490
4bfxZVXPantothenate kinase2.7.1.330.489
4uovAZMCarbonate dehydratase/0.488
1h50FMNPentaerythritol tetranitrate reductase/0.487
3fhxPXLPyridoxal kinase2.7.1.350.487
4j8tDOGUncharacterized PhzA/B-like protein PA3332/0.487
3h3qH13Collagen type IV alpha-3-binding protein/0.486
2w6cBM4Acetylcholinesterase3.1.1.70.485
1vyrFMNPentaerythritol tetranitrate reductase/0.484
3jypNADQuinate/shikimate dehydrogenase (NAD(+))/0.483
4b4w9L9Bifunctional protein FolD/0.483
4k0tD9ZCarbonic anhydrase 24.2.1.10.481
1kkq471Peroxisome proliferator-activated receptor alpha/0.480
1akbPPDAspartate aminotransferase, mitochondrial2.6.1.10.479
2rqfJH3Hemolymph juvenile hormone binding protein/0.478
3p74FMNPentaerythritol tetranitrate reductase/0.478
4bfvZVVPantothenate kinase2.7.1.330.478
1x8lOXRRetinol dehydratase/0.477
4psbGA3Cytokinin-specific binding protein/0.477
1c7oPPGHemolysin/0.476
3a6rFMNFMN-binding protein/0.476
4rp8ASCAscorbate-specific PTS system EIIC component/0.476
1c9wNAPAldose reductase-related protein 2/0.475
3h3t16HCollagen type IV alpha-3-binding protein/0.475
3k8q22APurine nucleoside phosphorylase2.4.2.10.475
3nmpPYVAbscisic acid receptor PYL2/0.475
4a83DXCMajor pollen allergen Bet v 1-A/0.475
1rt9IMHPurine nucleoside phosphorylase2.4.2.10.474
2ea4F79Methionine aminopeptidase 2/0.474
3bxoUPPdTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose/0.474
2pzjNADPutative nucleotide sugar epimerase/ dehydratase/0.473
2q1uNADPutative nucleotide sugar epimerase/ dehydratase/0.473
3f03FMNPentaerythritol tetranitrate reductase/0.473
4boeCLRJapanin/0.473
3h3r14HCollagen type IV alpha-3-binding protein/0.472
4bfwZVWPantothenate kinase2.7.1.330.472
1ex75GPGuanylate kinase2.7.4.80.471
1ra2FOLDihydrofolate reductase1.5.1.30.471
4eb5PLPCysteine desulfurase IscS 2/0.471
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.470
3fr4F8AFatty acid-binding protein, adipocyte/0.470
3uweVJJAldo-keto reductase family 1 member C3/0.470
3vp6HLDGlutamate decarboxylase 14.1.1.150.470
1akaPLPAspartate aminotransferase, mitochondrial2.6.1.10.469
1qyxASDEstradiol 17-beta-dehydrogenase 11.1.1.620.469
1u1f183Uridine phosphorylase2.4.2.30.469
4jq4IMNAldo-keto reductase family 1 member C2/0.469
1rftPXMPyridoxal kinase2.7.1.350.468
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.468
3own3OXRenin3.4.23.150.468
3s3vTOPDihydrofolate reductase1.5.1.30.468
1rr6IMHPurine nucleoside phosphorylase2.4.2.10.467
3aosJH2Hemolymph juvenile hormone binding protein/0.467
3apwDP0Alpha-1-acid glycoprotein 2/0.467
1jf2CZHObelin/0.466
1x1dSAHC-20 methyltransferase/0.466
2zbaZBATrichothecene 3-O-acetyltransferase/0.466
4b4vL34Bifunctional protein FolD/0.466
4bftZVTPantothenate kinase2.7.1.330.466
4iah1DXAlr2278 protein/0.466
1xe65FPPlasmepsin-23.4.23.390.465
2abbFMNPentaerythritol tetranitrate reductase/0.465
2q1sNAIPutative nucleotide sugar epimerase/ dehydratase/0.465
3jyqNADQuinate/shikimate dehydrogenase (NAD(+))/0.465
3qvrFADGlucose oxidase1.1.3.40.465
4mihFADPyranose 2-oxidase1.1.3.100.465
2rds1PL1-deoxypentalenic acid 11-beta-hydroxylase1.14.11.350.464
2vigFADShort-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.10.464
3dys5GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.464
4q71FADBifunctional protein PutA/0.464
1rzuADPGlycogen synthase 12.4.1.210.463
1x1bSAHC-20 methyltransferase/0.463
2xuiTZ5Acetylcholinesterase3.1.1.70.463
3c3xNAPEugenol synthase 11.1.1.3180.463
4a81DXCMajor pollen allergen Bet v 1-A/0.463
1b2lNDCAlcohol dehydrogenase1.1.1.10.462
1s64778Geranylgeranyl transferase type-1 subunit beta2.5.1.590.462
2zs9ADPPantothenate kinase2.7.1.330.462
3mtwM3RXaa-Pro dipeptidase, putative/0.462
4fam0SZAldo-keto reductase family 1 member C3/0.462
4pnmNU1Tankyrase-22.4.2.300.462
4y1bNAPAntE/0.462
3p8iFMNPentaerythritol tetranitrate reductase/0.461
4drjRAPSerine/threonine-protein kinase mTOR2.7.11.10.461
4drjRAPPeptidyl-prolyl cis-trans isomerase FKBP45.2.1.80.461
4iae1DXAlr2278 protein/0.461
1kyxCRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.460
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.460
3dylIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.460
3w6hAZMCarbonic anhydrase 14.2.1.10.460
4bfuZVUPantothenate kinase2.7.1.330.460
1el4CTZObelin/0.459
1fmjRTLRetinol dehydratase/0.459
1h51FMNPentaerythritol tetranitrate reductase/0.459
1qoqIGPTryptophan synthase alpha chain/0.459
1s36CEIObelin/0.459
2gv8NDPThiol-specific monooxygenase1.14.130.459
3h3sH15Collagen type IV alpha-3-binding protein/0.459
3ntrNADInositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase1.1.1.180.459
3p62FMNPentaerythritol tetranitrate reductase/0.459
4p9dTMPDeoxycytidylate deaminase/0.459
1rszDIHPurine nucleoside phosphorylase2.4.2.10.458
1t7o152Carnitine O-acetyltransferase2.3.1.70.458
2q1tNADPutative nucleotide sugar epimerase/ dehydratase/0.458
3eon341Glutaryl-CoA dehydrogenase/0.458
4a802ANMajor pollen allergen Bet v 1-A/0.458
4a86H35Major pollen allergen Bet v 1-A/0.458
4g2l0WLHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.458
1xddAAYIntegrin alpha-L/0.457
2g1n1IGRenin3.4.23.150.457
2g25TDKPyruvate dehydrogenase E1 component1.2.4.10.457
2idkC2FGlycine N-methyltransferase2.1.1.200.457
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.457
4a862ANMajor pollen allergen Bet v 1-A/0.457
1xvaSAMGlycine N-methyltransferase2.1.1.200.456
3p67FMNPentaerythritol tetranitrate reductase/0.456
1bim0QBRenin3.4.23.150.455
1lgtBP3Biphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.455
1q45FMN12-oxophytodienoate reductase 31.3.1.420.455
2e0nSAHPrecorrin-2 C20-methyltransferase/0.455
2gesCOKPantothenate kinase2.7.1.330.455
2i7pACOPantothenate kinase 32.7.1.330.455
2yy2IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.455
3hxcBD6Geranylgeranyl transferase type-2 subunit beta2.5.1.600.455
4oe4NADDelta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial1.2.1.880.455
4q0kGA3Phytohormone-binding protein/0.455
4xsvC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.455
5a0yCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.455
5a0yCOMMethyl-coenzyme M reductase I subunit beta2.8.4.10.455
2a1hGBNBranched-chain-amino-acid aminotransferase, mitochondrial2.6.1.420.454
2e9aB28Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.454
3gfbNADL-threonine 3-dehydrogenase/0.454
4f0rMTA5-methylthioadenosine/S-adenosylhomocysteine deaminase/0.454
4n1fCZHObelin/0.454
1dmyAZMCarbonic anhydrase 5A, mitochondrial4.2.1.10.453
2a92NAIL-lactate dehydrogenase/0.453
3bgsDIHPurine nucleoside phosphorylase2.4.2.10.453
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.453
3fr5I4AFatty acid-binding protein, adipocyte/0.453
3g5sFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.453
4eplJAIJasmonic acid-amido synthetase JAR16.3.20.453
4r81FMNPredicted NADH dehydrogenase/0.453
1mewXMPInosine-5'-monophosphate dehydrogenase/0.452
2j3qTFLAcetylcholinesterase3.1.1.70.452
2rh9IGPTryptophan synthase alpha chain/0.452
3dr7GPDGDP-perosamine synthase/0.452
3zs7ATPPyridoxine/pyridoxal/pyridoxamine kinase/0.452
4i6gFADCryptochrome-2/0.452
7stdCRPScytalone dehydratase4.2.1.940.452
1bwsNDPGDP-L-fucose synthase/0.451
1foaUD1Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase2.4.1.1010.451
1qyw5SDEstradiol 17-beta-dehydrogenase 11.1.1.620.451
1xorZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.451
2a0yDIHPurine nucleoside phosphorylase2.4.2.10.451
2g1s4IGRenin3.4.23.150.451
2q3oFMN12-oxophytodienoate reductase 31.3.1.420.451
2xviFADPutative flavin-containing monooxygenase/0.451
3cavCI23-oxo-5-beta-steroid 4-dehydrogenase/0.451
3own3OWRenin3.4.23.150.451
3stdMQ0Scytalone dehydratase4.2.1.940.451
4dbc3QPAspartate aminotransferase2.6.1.10.451
4n1gCEIObelin/0.451
1ps9MDE2,4-dienoyl-CoA reductase1.3.1.340.450
1psa0ZLPepsin A3.4.23.10.450
2a0wDIHPurine nucleoside phosphorylase2.4.2.10.450
2aq8NAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.450
2v3wTPPBenzoylformate decarboxylase4.1.1.70.450
3gwfNAPCyclohexanone monooxygenase/0.450
3jzfJZKBiotin carboxylase6.3.4.140.450
4e2bFMNDehydrogenase/0.450
4giu636Anthranilate phosphoribosyltransferase/0.450
1gaxVAAValine--tRNA ligase6.1.1.90.449
1h63FMNPentaerythritol tetranitrate reductase/0.449
1rneC60Renin3.4.23.150.449
2hxzH7JCathepsin S3.4.22.270.449
2vbpVB1Isopenicillin N synthase1.21.3.10.449
2zs8ADPPantothenate kinase2.7.1.330.449
3koo24DBifunctional epoxide hydrolase 23.3.2.100.449
4w5kPLPAspartate aminotransferase, mitochondrial/0.449
1o6qR17Squalene--hopene cyclase4.2.1.1290.448
1q0rAKTAclacinomycin methylesterase RdmC3.1.1.950.448
2hs6FMN12-oxophytodienoate reductase 31.3.1.420.448
2j9lATPH(+)/Cl(-) exchange transporter 5/0.448
2wu4HBPAcetylcholinesterase3.1.1.70.448
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.448
3lqfNADGalactitol dehydrogenase/0.448
3zbzOVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.448
4bjbP34Tankyrase-22.4.2.300.448
4dc0NDPPutative ketoacyl reductase1.3.10.448
4fl0PLPAminotransferase ALD1, chloroplastic2.6.10.448
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.448
4xrbNDPPossible bifunctional enzyme riboflavin biosynthesis protein RibD: diaminohydroxyphosphoribosylaminopyrimidine deaminase (Riboflavin-specific deaminase) + 5-amino-6-(5-phosphoribosylamino)uracil reduc/0.448
6gsuGPSGlutathione S-transferase Mu 12.5.1.180.448
1gpdNADGlyceraldehyde-3-phosphate dehydrogenase1.2.1.120.447
1ut6A8NAcetylcholinesterase3.1.1.70.447
1w6hTITPlasmepsin-23.4.23.390.447
1ygjRMCPyridoxal kinase2.7.1.350.447
2fr0NDP6-deoxyerythronolide-B synthase EryA1, modules 1 and 2/0.447
2g1o2IGRenin3.4.23.150.447
2j09FMNDeoxyribodipyrimidine photo-lyase4.1.99.30.447
3h2sNDPPutative NADH-flavin reductase/0.447
3pftFMNFlavin reductase/0.447
3sxjSAMPutative methyltransferase/0.447
3vy5FMNFMN-binding protein/0.447
4c1eMCOBeta-lactamase class B VIM-2/0.447
4kbyC2EStimulator of interferon genes protein/0.447
4x5gFOLDihydrofolate reductase1.5.1.30.447
4xba5GPAprataxin-like protein30.447
5c3jUQ1Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial/0.447
5c3jUQ1Succinate dehydrogenase cytochrome b560/0.447
1d4aFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.446
1lkdBP6Biphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.446
1obnASVIsopenicillin N synthase1.21.3.10.446
1p0pBCHCholinesterase3.1.1.80.446
1tllFMNNitric oxide synthase, brain1.14.13.390.446
1zbdGTPRas-related protein Rab-3A/0.446
2vn1FK5Peptidylprolyl isomerase/0.446
3v2uATPProtein GAL3/0.446
4eb7PLPCysteine desulfurase IscS 2/0.446
4eqsCOACoenzyme A disulfide reductase/0.446
4fmxCNL1,8-cineole 2-endo-monooxygenase1.14.13.1560.446
4g2j0WFHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.446
1dtpAPUDiphtheria toxin/0.445
1rfgGMPPurine nucleoside phosphorylase2.4.2.10.445
1rx8FOLDihydrofolate reductase1.5.1.30.445
2cekN8TAcetylcholinesterase3.1.1.70.445
2cy0NAPShikimate dehydrogenase (NADP(+))/0.445
2e83FMNFMN-binding protein/0.445
2ewvADPTwitching motility protein PilT/0.445
2rlcCHDCholoylglycine hydrolase3.5.1.240.445
2w6pOA4Biotin carboxylase6.3.4.140.445
3o76GTBGlutathione S-transferase P 12.5.1.180.445
3r43ID8Aldo-keto reductase family 1 member C3/0.445
3tqxPLP2-amino-3-ketobutyrate coenzyme A ligase/0.445
3vyfVYFRenin3.4.23.150.445
4cf6CBDNAD(P)H dehydrogenase [quinone] 11.6.5.20.445
4xiwAZMCarbonic anhydrase, alpha type/0.445
4ycpFMNtRNA-dihydrouridine(16) synthase/0.445
1akcPPEAspartate aminotransferase, mitochondrial2.6.1.10.444
1bl4AP1Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.444
1crbRTLRetinol-binding protein 1/0.444
1fmlRTLRetinol dehydratase/0.444
1gky5GPGuanylate kinase2.7.4.80.444
1h60STRPentaerythritol tetranitrate reductase/0.444
1n4sCYS_VAL_ILE_LEU_GERGeranylgeranyl transferase type-1 subunit beta2.5.1.590.444
1nlmUD1UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase/0.444
1pd9CO4Dihydrofolate reductase1.5.1.30.444
1r6uTYMTryptophan--tRNA ligase, cytoplasmic6.1.1.20.444
1x1cSAHC-20 methyltransferase/0.444
2abaSTRPentaerythritol tetranitrate reductase/0.444
2bjfDXCCholoylglycine hydrolase3.5.1.240.444
2e8uIPEGeranylgeranyl pyrophosphate synthase/0.444
2ea2F77Methionine aminopeptidase 2/0.444
2v2zADP4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.444
2y60M8FIsopenicillin N synthase1.21.3.10.444
3pl8FADPyranose 2-oxidase/0.444
3qj0QI3Botulinum neurotoxin type A3.4.24.690.444
3rsv3RSBeta-secretase 13.4.23.460.444
4a87NARMajor pollen allergen Bet v 1-A/0.444
4fxy0W2Neurolysin, mitochondrial3.4.24.160.444
4mrm2BYGamma-aminobutyric acid type B receptor subunit 1/0.444
4relKMPGlycosyltransferase/0.444
1enoNADEnoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic1.3.1.90.443
1h36R88Squalene--hopene cyclase4.2.1.1290.443
1me6IVSPlasmepsin-23.4.23.390.443
1rkwPNTHTH-type transcriptional regulator QacR/0.443
1swtBTNStreptavidin/0.443
1yw7A41Methionine aminopeptidase 2/0.443
2c4iBTNAvidin/0.443
2fk8SAMHydroxymycolate synthase MmaA42.1.10.443
2gbyBRNHTH-type transcriptional regulator QacR/0.443
3aezGDPPantothenate kinase2.7.1.330.443
3wv9FEGHmd co-occurring protein HcgE/0.443
4fhf0TTSpore photoproduct lyase/0.443
4x7zZM3Mycinamicin III 3''-O-methyltransferase2.1.1.2370.443
6gsvGPSGlutathione S-transferase Mu 12.5.1.180.443
1fm4DXCMajor pollen allergen Bet v 1-L/0.442
1gpeFADGlucose oxidase1.1.3.40.442
1yryMSGPurine nucleoside phosphorylase2.4.2.10.442
2abjCBCBranched-chain-amino-acid aminotransferase, cytosolic2.6.1.420.442
2oc4IMHPurine nucleoside phosphorylase2.4.2.10.442
2pncCLUPrimary amine oxidase, liver isozyme/0.442
2v2vV124-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.442
2v2zCDM4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.442
3b1dPLSBetaC-S lyase/0.442
3m1vCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.442
3m1vCOMMethyl-coenzyme M reductase I subunit beta2.8.4.10.442
3qrwNDPPutative ketoacyl reductase1.3.10.442
4c1iEH9cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.442
4rlsNAIL-lactate dehydrogenase A chain1.1.1.270.442
1bk0ACVIsopenicillin N synthase1.21.3.10.441
1cf3FADGlucose oxidase1.1.3.40.441
1n5vNOMActVA 6 protein/0.441
1t9gFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.441
1touB1VFatty acid-binding protein, adipocyte/0.441
1x1aSAMC-20 methyltransferase/0.441
1yw9A84Methionine aminopeptidase 2/0.441
2hveADPNucleoside diphosphate kinase A2.7.4.60.441
2jl1NAPTriphenylmethane reductase/0.441
2onmADPAldehyde dehydrogenase, mitochondrial1.2.1.30.441
3nbrASDSteroid Delta-isomerase5.3.3.10.441
3nyrMLCPutative fatty acid synthase/0.441
3vy2FMNFMN-binding protein/0.441
4jicFMNGTN Reductase/0.441
4xo7ASDAldo-keto reductase family 1 member C2/0.441
5b1yNDP3-oxoacyl-[acyl-carrier-protein] reductase/0.441
1m13HYFNuclear receptor subfamily 1 group I member 2/0.440
1o9bNAIQuinate/shikimate dehydrogenase/0.440
2c20NADUDP-glucose 4-epimerase/0.440
2dxdANPNucleoside diphosphate kinase2.7.4.60.440
2g247IGRenin3.4.23.150.440
2i65NADADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 13.2.2.60.440
2j07HDFDeoxyribodipyrimidine photo-lyase4.1.99.30.440
2rd2QSIGlutamine--tRNA ligase6.1.1.180.440
2wp9CBESuccinate dehydrogenase iron-sulfur subunit1.3.5.10.440
2wp9CBESuccinate dehydrogenase cytochrome b556 subunit/0.440
3af1GDPPantothenate kinase2.7.1.330.440
3dyqIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.440
3fr28CAFatty acid-binding protein, adipocyte/0.440
3gkaFMNN-ethylmaleimide reductase/0.440
3hdyGDUUDP-galactopyranose mutase/0.440
3hl0NADMaleylacetate reductase/0.440
3jswJARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.440
3mnrSD1Heat shock protein HSP 90-alpha/0.440
3qi4IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.440
4awsFMNNADH:flavin oxidoreductase Sye1/0.440
4bgePYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.440
4j491J1Uncharacterized protein/0.440
4xymCOAAcyl-CoA synthetase (NDP forming)/0.440
4zj8SUVOrexin receptor type 1/0.440