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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4fk60UJTyrosine-protein kinase JAK1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4fk60UJTyrosine-protein kinase JAK1/1.000
4ehzJAKTyrosine-protein kinase JAK1/0.616
4e5w0NTTyrosine-protein kinase JAK1/0.599
4ivb1J5Tyrosine-protein kinase JAK1/0.593
4e6d0NUTyrosine-protein kinase JAK2/0.584
4f081RSTyrosine-protein kinase JAK2/0.578
4e4l0NHTyrosine-protein kinase JAK1/0.571
4i5cC5ITyrosine-protein kinase JAK1/0.567
4aqc88ATyrosine-protein kinase JAK2/0.565
2vv9IM9Cyclin-dependent kinase 22.7.11.220.563
3zh8C58Protein kinase C iota type2.7.11.130.556
4k771Q4Tyrosine-protein kinase JAK1/0.551
4ji91M3Tyrosine-protein kinase JAK2/0.546
4hge15VTyrosine-protein kinase JAK2/0.544
3iok1P6Tyrosine-protein kinase JAK2/0.537
4e6q0NVTyrosine-protein kinase JAK2/0.537
4ei40Q2Tyrosine-protein kinase JAK1/0.535
4ivd15TTyrosine-protein kinase JAK1/0.532
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.532
4kikKSAInhibitor of nuclear factor kappa-B kinase subunit beta2.7.11.100.531
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.530
4bgh3I6Cyclin-dependent kinase 22.7.11.220.528
4e200MYNon-receptor tyrosine-protein kinase TYK22.7.10.20.528
1fvv107Cyclin-dependent kinase 22.7.11.220.527
3rak03ZCyclin-dependent kinase 22.7.11.220.527
4iwq1FVSerine/threonine-protein kinase TBK12.7.11.10.521
4hvi19STyrosine-protein kinase JAK32.7.10.20.518
2b9iADPMitogen-activated protein kinase FUS32.7.11.240.517
4eutBX7Serine/threonine-protein kinase TBK12.7.11.10.517
3lxkMI1Tyrosine-protein kinase JAK32.7.10.20.513
4bbfO19Tyrosine-protein kinase JAK2/0.513
2x8iX8ISerine/threonine-protein kinase Chk12.7.11.10.512
4fv5EK9Mitogen-activated protein kinase 12.7.11.240.509
3cblSTUTyrosine-protein kinase Fes/Fps2.7.10.20.507
1p2a5BNCyclin-dependent kinase 22.7.11.220.505
3cd3STUTyrosine-protein kinase Fes/Fps2.7.10.20.505
3zep1NXTyrosine-protein kinase JAK32.7.10.20.505
1yvj4STTyrosine-protein kinase JAK32.7.10.20.504
3ncz3NCRho-associated protein kinase 12.7.11.10.504
1h0w207Cyclin-dependent kinase 22.7.11.220.503
3rvg17PTyrosine-protein kinase JAK2/0.503
4fv6E57Mitogen-activated protein kinase 12.7.11.240.503
2w17I19Cyclin-dependent kinase 22.7.11.220.502
3ggfGVDSerine/threonine-protein kinase 26/0.500
4im01FVSerine/threonine-protein kinase TBK12.7.11.10.500
3uli1N3Cyclin-dependent kinase 22.7.11.220.499
1bxqPP8Penicillopepsin-13.4.23.200.497
1w8cN69Cyclin-dependent kinase 22.7.11.220.497
4c61LMMTyrosine-protein kinase JAK2/0.497
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.496
3eyhIZATyrosine-protein kinase JAK1/0.495
3zc6VFCTyrosine-protein kinase JAK32.7.10.20.495
2ycfYCFSerine/threonine-protein kinase Chk22.7.11.10.493
3rk708ZCyclin-dependent kinase 22.7.11.220.493
3rkb12ZCyclin-dependent kinase 22.7.11.220.493
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.493
2b7aIZATyrosine-protein kinase JAK2/0.492
4erwSTUCyclin-dependent kinase 22.7.11.220.492
2r3iSCFCyclin-dependent kinase 22.7.11.220.491
1e1xNW1Cyclin-dependent kinase 22.7.11.220.490
1pxpCK8Cyclin-dependent kinase 22.7.11.220.489
3t113T1Gag-Pol polyprotein3.4.23.160.489
2xa4AZ5Tyrosine-protein kinase JAK2/0.488
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.488
3lpbNVBTyrosine-protein kinase JAK2/0.488
3qtrX36Cyclin-dependent kinase 22.7.11.220.488
1g5sI17Cyclin-dependent kinase 22.7.11.220.487
1ke6LS2Cyclin-dependent kinase 22.7.11.220.487
1ppm0P1Penicillopepsin-13.4.23.200.487
3rk507ZCyclin-dependent kinase 22.7.11.220.487
1urwI1PCyclin-dependent kinase 22.7.11.220.486
2c6lDT4Cyclin-dependent kinase 22.7.11.220.486
2eufLQQCyclin-dependent kinase 62.7.11.220.486
3mtfA3FActivin receptor type-12.7.11.300.486
5dpvSKEAurora kinase A2.7.11.10.486
1pkdUCNCyclin-dependent kinase 22.7.11.220.485
1pxlCK4Cyclin-dependent kinase 22.7.11.220.485
4fod0UVALK tyrosine kinase receptor2.7.10.10.485
4im2BX7Serine/threonine-protein kinase TBK12.7.11.10.485
1y91CT9Cyclin-dependent kinase 22.7.11.220.484
1ykr628Cyclin-dependent kinase 22.7.11.220.484
3r8lZ30Cyclin-dependent kinase 22.7.11.220.484
4ez50RSCyclin-dependent kinase 62.7.11.220.484
1pxmCK5Cyclin-dependent kinase 22.7.11.220.483
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.483
5dt0SKEAurora kinase A2.7.11.10.482
1gih1PUCyclin-dependent kinase 22.7.11.220.481
3kddJZQGag-Pol polyprotein3.4.23.160.481
3lq5SLQCyclin-dependent kinase 92.7.11.220.481
3r2b05BMAP kinase-activated protein kinase 22.7.11.10.481
4nifANPMitogen-activated protein kinase 12.7.11.240.481
2r3jSCJCyclin-dependent kinase 22.7.11.220.480
4fkv61KCyclin-dependent kinase 22.7.11.220.480
4oa9ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.480
1bxoPP7Penicillopepsin-13.4.23.200.479
2vthLZ2Cyclin-dependent kinase 22.7.11.220.479
2x1nX1NCyclin-dependent kinase 22.7.11.220.479
3gxlQIGTGF-beta receptor type-12.7.11.300.479
1eh4IC1Casein kinase I homolog 12.7.11.10.478
1ppl1Z7Penicillopepsin-13.4.23.200.478
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.478
2w1hL0FCyclin-dependent kinase 22.7.11.220.478
3sheI85MAP kinase-activated protein kinase 32.7.11.10.478
4gmy0X5Tyrosine-protein kinase JAK2/0.478
4hvh19RTyrosine-protein kinase JAK32.7.10.20.478
4ivc1J6Tyrosine-protein kinase JAK1/0.478
4o0wADNAurora kinase A2.7.11.10.478
4oh4ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.478
3i4bZ48Glycogen synthase kinase-3 beta2.7.11.260.477
3qd03Q43-phosphoinositide-dependent protein kinase 12.7.11.10.477
3s1h56ZCyclin-dependent kinase 22.7.11.220.477
4btjATPTau-tubulin kinase 12.7.11.10.477
4dit0KDGlycogen synthase kinase-3 beta2.7.11.260.477
4dymIYZActivin receptor type-12.7.11.300.477
2uxpCLMHTH-type transcriptional regulator TtgR/0.476
2uzbC75Cyclin-dependent kinase 22.7.11.220.476
2xbjXBJSerine/threonine-protein kinase Chk22.7.11.10.476
3rpo24ZCyclin-dependent kinase 22.7.11.220.476
3tnwF18Cyclin-dependent kinase 22.7.11.220.476
1snuSTUTyrosine-protein kinase ITK/TSK2.7.10.20.475
3qtuX44Cyclin-dependent kinase 22.7.11.220.475
3r83Z14Cyclin-dependent kinase 22.7.11.220.475
3zm422TDual specificity mitogen-activated protein kinase kinase 12.7.12.20.475
4dt9GMPAPH(2'')-Id/0.475
4iva1J5Tyrosine-protein kinase JAK2/0.475
2pvhP19Casein kinase II subunit alpha2.7.11.10.474
2vtpLZ9Cyclin-dependent kinase 22.7.11.220.474
2vtqLZACyclin-dependent kinase 22.7.11.220.474
3lfqA28Cyclin-dependent kinase 22.7.11.220.474
4eomATPCyclin-dependent kinase 22.7.11.220.474
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.10.474
1bygSTUTyrosine-protein kinase CSK/0.473
1gii1PUCyclin-dependent kinase 22.7.11.220.473
2izuP01Casein kinase I isoform gamma-32.7.11.10.473
2pmoHMDProtein kinase 7/0.473
2xb7GUIALK tyrosine kinase receptor2.7.10.10.473
2xmyCDKCyclin-dependent kinase 22.7.11.220.473
3fz1B98Cyclin-dependent kinase 22.7.11.220.473
3pj8404Cyclin-dependent kinase 22.7.11.220.473
4dn5AGSMitogen-activated protein kinase kinase kinase 142.7.11.250.473
4nj32KDCyclin-dependent kinase 22.7.11.220.473
2vttLZDCyclin-dependent kinase 22.7.11.220.472
3sw418KCyclin-dependent kinase 22.7.11.220.472
4hvg19QTyrosine-protein kinase JAK32.7.10.20.472
4k6z1Q3Tyrosine-protein kinase JAK1/0.472
3rahO1ZCyclin-dependent kinase 22.7.11.220.471
4ewhT77Activated CDC42 kinase 1/0.471
4wsqKSAAP2-associated protein kinase 12.7.11.10.471
5e8ySTUTGF-beta receptor type-22.7.11.300.471
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.470
2vtoLZ8Cyclin-dependent kinase 22.7.11.220.470
2vtsLZCCyclin-dependent kinase 22.7.11.220.470
3bkbSTUTyrosine-protein kinase Fes/Fps2.7.10.20.470
3nux3NVCyclin-dependent kinase 62.7.11.220.470
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.470
4fko20KCyclin-dependent kinase 22.7.11.220.470
4fmqANPMitogen-activated protein kinase 12.7.11.240.470
4q5jANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.470
2uzdC85Cyclin-dependent kinase 22.7.11.220.469
2uzoC62Cyclin-dependent kinase 22.7.11.220.469
3eb0DRKUncharacterized protein/0.469
3f69XDRSerine/threonine-protein kinase PknB2.7.11.10.469
1ppkIVVPenicillopepsin-13.4.23.200.468
1pyePM1Cyclin-dependent kinase 22.7.11.220.468
2r3kSCQCyclin-dependent kinase 22.7.11.220.468
3ezvEZVCyclin-dependent kinase 22.7.11.220.468
3zmmF9JTyrosine-protein kinase JAK2/0.468
4da8BG2Purine nucleoside phosphorylase DeoD-type2.4.2.10.468
4foc0UUALK tyrosine kinase receptor2.7.10.10.468
2b9fADPMitogen-activated protein kinase FUS32.7.11.240.467
4anuEM7Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.467
4fv3EK6Mitogen-activated protein kinase 12.7.11.240.467
4qmtH1NSerine/threonine-protein kinase 242.7.11.10.467
5ar4SB2Receptor-interacting serine/threonine-protein kinase 22.7.11.10.467
1gij2PUCyclin-dependent kinase 22.7.11.220.466
1stcSTUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.466
2b53D23Cyclin-dependent kinase 22.7.11.220.466
2c6kDT2Cyclin-dependent kinase 22.7.11.220.466
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.466
3sc13S13-phosphoinositide-dependent protein kinase 12.7.11.10.466
4acm7YGCyclin-dependent kinase 22.7.11.220.466
4fks46KCyclin-dependent kinase 22.7.11.220.466
4fkw62KCyclin-dependent kinase 22.7.11.220.466
4ijp1EHSerine/threonine-protein kinase PRP4 homolog2.7.11.10.466
1w0xOLOCyclin-dependent kinase 22.7.11.220.465
2in6839Wee1-like protein kinase2.7.10.20.465
3lfnA27Cyclin-dependent kinase 22.7.11.220.465
3zptM8YGag-Pol polyprotein3.4.23.160.465
4btmF8ETau-tubulin kinase 12.7.11.10.465
4fklCK2Cyclin-dependent kinase 22.7.11.220.465
4fv1EK4Mitogen-activated protein kinase 12.7.11.240.465
4fv7E94Mitogen-activated protein kinase 12.7.11.240.465
1oitHDTCyclin-dependent kinase 22.7.11.220.464
1okzUCN3-phosphoinositide-dependent protein kinase 12.7.11.10.464
2gnhH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.464
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.464
2vu3LZECyclin-dependent kinase 22.7.11.220.464
3hmm855TGF-beta receptor type-12.7.11.300.464
3qxpX64Cyclin-dependent kinase 22.7.11.220.464
4ye3G04Gag-Pol polyprotein3.4.23.160.464
2b9jADPMitogen-activated protein kinase FUS32.7.11.240.463
2r3lSCWCyclin-dependent kinase 22.7.11.220.463
3oroAGSSerine/threonine protein kinase/0.463
3r73X87Cyclin-dependent kinase 22.7.11.220.463
3r7uX96Cyclin-dependent kinase 22.7.11.220.463
1h1r6CPCyclin-dependent kinase 22.7.11.220.462
1ke7LS3Cyclin-dependent kinase 22.7.11.220.462
1ny3ADPMAP kinase-activated protein kinase 22.7.11.10.462
1u4dDBQActivated CDC42 kinase 1/0.462
2j0m4STFocal adhesion kinase 12.7.10.20.462
3kn5ANPRibosomal protein S6 kinase alpha-52.7.11.10.462
4bibIEOMitogen-activated protein kinase kinase kinase 52.7.11.250.462
4fkt48KCyclin-dependent kinase 22.7.11.220.462
4h3qANPMitogen-activated protein kinase 12.7.11.240.462
4iqlFMNEnoyl-(Acyl-carrier-protein) reductase II/0.462
2r7b2533-phosphoinositide-dependent protein kinase 12.7.11.10.461
2wecPP5Penicillopepsin-13.4.23.200.461
3r8vZ62Cyclin-dependent kinase 22.7.11.220.461
1oguST8Cyclin-dependent kinase 22.7.11.220.460
2c6o4SPCyclin-dependent kinase 22.7.11.220.460
2cchATPCyclin-dependent kinase 22.7.11.220.460
3bheBZNGag-Pol polyprotein3.4.23.160.460
3bhh5CPCalcium/calmodulin-dependent protein kinase type II subunit beta2.7.11.170.460
3bxsDRSGag-Pol polyprotein3.4.23.160.460
3qtxX43Cyclin-dependent kinase 22.7.11.220.460
4ft0HK9Serine/threonine-protein kinase Chk12.7.11.10.460
4gh2HK0Serine/threonine-protein kinase Chk12.7.11.10.460
4mvfSTUCalcium-dependent protein kinase 22.7.11.10.460
1nfbNADInosine-5'-monophosphate dehydrogenase 2/0.459
2b52D42Cyclin-dependent kinase 22.7.11.220.459
2fvdLIACyclin-dependent kinase 22.7.11.220.459
2ojj82AMitogen-activated protein kinase 12.7.11.240.459
2uztSS3cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.459
3awhFMNFMN-binding protein/0.459
4bgg844Activin receptor type-12.7.11.300.459
4ic7ANPMitogen-activated protein kinase 72.7.11.240.459
4u9aSTUInterleukin-1 receptor-associated kinase 42.7.11.10.459
1h1s4SPCyclin-dependent kinase 22.7.11.220.458
4e4m0NHTyrosine-protein kinase JAK2/0.458
4ek816KCyclin-dependent kinase 22.7.11.220.458
4eor4SPCyclin-dependent kinase 22.7.11.220.458
1aq1STUCyclin-dependent kinase 22.7.11.220.457
1oirHDYCyclin-dependent kinase 22.7.11.220.457
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.457
2cdz23DSerine/threonine-protein kinase PAK 42.7.11.10.457
2owkSAHDiphthine synthase/0.457
3a60STURibosomal protein S6 kinase beta-12.7.11.10.457
3le62BZCyclin-dependent kinase 22.7.11.220.457
3rmf20ZCyclin-dependent kinase 22.7.11.220.457
4dtaADNAPH(2'')-Id/0.457
4i8zG08Gag-Pol polyprotein3.4.23.160.457
1k6pXN3Gag-Pol polyprotein3.4.23.160.456
2r3gSC9Cyclin-dependent kinase 22.7.11.220.456
3gu83GUDeath-associated protein kinase 12.7.11.10.456
3i60E86Mitogen-activated protein kinase 12.7.11.240.456
3qd33Q53-phosphoinositide-dependent protein kinase 12.7.11.10.456
3r9nZ68Cyclin-dependent kinase 22.7.11.220.456
4qnyANPMitogen activated protein kinase, putative/0.456
1i7gAZ2Peroxisome proliferator-activated receptor alpha/0.455
2c6iDT1Cyclin-dependent kinase 22.7.11.220.455
3a62STURibosomal protein S6 kinase beta-12.7.11.10.455
3bbrBHYGlutamate receptor 2/0.455
3qcq3Q03-phosphoinositide-dependent protein kinase 12.7.11.10.455
3qd43Q63-phosphoinositide-dependent protein kinase 12.7.11.10.455
3ti1B49Cyclin-dependent kinase 22.7.11.220.455
4fkr45KCyclin-dependent kinase 22.7.11.220.455
4qmpDKISerine/threonine-protein kinase 242.7.11.10.455
4z61ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.455
1finATPCyclin-dependent kinase 22.7.11.220.454
1hsgMK1Gag-Pol polyprotein/0.454
1oiqHDUCyclin-dependent kinase 22.7.11.220.454
2a0cCK9Cyclin-dependent kinase 22.7.11.220.454
2cgu3A3Serine/threonine-protein kinase Chk12.7.11.10.454
2evaADNMitogen-activated protein kinase kinase kinase 72.7.11.250.454
2pe24643-phosphoinositide-dependent protein kinase 12.7.11.10.454
3csoXNIGenome polyprotein2.7.7.480.454
3nynSGVG protein-coupled receptor kinase 62.7.11.160.454
3rni21ZCyclin-dependent kinase 22.7.11.220.454
4fsnA58Serine/threonine-protein kinase Chk12.7.11.10.454
1phgMYTCamphor 5-monooxygenase1.14.15.10.453
1sguMK1Gag-Pol polyprotein3.4.23.160.453
3ddpRC8Cyclin-dependent kinase 22.7.11.220.453
4cd0AWJALK tyrosine kinase receptor2.7.10.10.453
4jr7GNPCasein kinase II subunit alpha2.7.11.10.453
5ackATP3-phosphoinositide-dependent protein kinase 12.7.11.10.453
1e82M90Endothiapepsin3.4.23.220.452
1xl2189Gag-Pol polyprotein3.4.23.160.452
2f2uM77Rho-associated protein kinase 22.7.11.10.452
3biz61EWee1-like protein kinase2.7.10.20.452
3ik6HCZGlutamate receptor 2/0.452
3lfsA07Cyclin-dependent kinase 22.7.11.220.452
3oy4017Gag-Pol polyprotein3.4.23.160.452
3t4nADP5'-AMP-activated protein kinase subunit gamma/0.452
4cztCPSCBL-interacting serine/threonine-protein kinase 232.7.11.10.452
5c8wPCGcGMP-dependent protein kinase 22.7.11.120.452
1odx0E8Gag-Pol polyprotein3.4.23.160.451
1sxjADPReplication factor C subunit 5/0.451
1xe55FEPlasmepsin-23.4.23.390.451
2cgx3D3Serine/threonine-protein kinase Chk12.7.11.10.451
2r38G4GGag-Pol polyprotein3.4.23.160.451
3bc3OPTCathepsin L13.4.22.150.451
3hx4ANPCalmodulin-domain protein kinase 1/0.451
3pe2E1BCasein kinase II subunit alpha2.7.11.10.451
3qzgX67Cyclin-dependent kinase 22.7.11.220.451
4cdmFADDeoxyribodipyrimidine photolyase/0.451
4fszHK8Serine/threonine-protein kinase Chk12.7.11.10.451
4o0rX4ZSerine/threonine-protein kinase PAK 12.7.11.10.451
4s34ANPMitogen-activated protein kinase 12.7.11.240.451
1m2rMNYCasein kinase II subunit alpha2.7.11.10.450
1y8yCT7Cyclin-dependent kinase 22.7.11.220.450
2bhiSFTCytotoxin 3/0.450
2hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.450
2p5cSAHDiphthine synthase/0.450
2qnqQN3Gag-Pol polyprotein3.4.23.160.450
3nieANPMitogen-activated protein kinase/0.450
4bcoT6QCyclin-dependent kinase 22.7.11.220.450
4ftiH7KSerine/threonine-protein kinase Chk12.7.11.10.450
4nbwNADShort-chain dehydrogenase/reductase SDR/0.450
5dr6SKEAurora kinase A2.7.11.10.450
1hckATPCyclin-dependent kinase 22.7.11.220.449
1j1cADPGlycogen synthase kinase-3 beta2.7.11.260.449
1pxjCK2Cyclin-dependent kinase 22.7.11.220.449
1tvoFRZMitogen-activated protein kinase 12.7.11.240.449
1xe65FPPlasmepsin-23.4.23.390.449
1zrzBI1Protein kinase C iota type2.7.11.130.449
2a94AP0L-lactate dehydrogenase1.1.1.270.449
2h96893Mitogen-activated protein kinase 82.7.11.240.449
2hckQUETyrosine-protein kinase HCK2.7.10.20.449
2ijmATPFocal adhesion kinase 12.7.10.20.449
2p5uNADUDP-glucose 4-epimerase/0.449
2vr1ATFBiotin carboxylase6.3.4.140.449
3v8t477Tyrosine-protein kinase ITK/TSK2.7.10.20.449
4hgs15GCasein kinase I isoform gamma-32.7.11.10.449
1e9hINRCyclin-dependent kinase 22.7.11.220.448
2dv7SAHDiphthine synthase/0.448
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.448
2egsSAHDiphthine synthase/0.448
2gcdSTUSerine/threonine-protein kinase TAO22.7.11.10.448
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.448
2uzeC95Cyclin-dependent kinase 22.7.11.220.448
2xchCKG3-phosphoinositide-dependent protein kinase 12.7.11.10.448
3ortAGSSerine/threonine protein kinase/0.448
4e1z0MXNon-receptor tyrosine-protein kinase TYK22.7.10.20.448
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.448
4o0uADNAurora kinase A2.7.11.10.448
5b1yNDP3-oxoacyl-[acyl-carrier-protein] reductase/0.448
1ia1NDPDihydrofolate reductase1.5.1.30.447
1py5PY1TGF-beta receptor type-12.7.11.300.447
2eniSAHDiphthine synthase/0.447
2j9mPY8Cyclin-dependent kinase 22.7.11.220.447
2x6dX6DAurora kinase A2.7.11.10.447
3bgqVX2Serine/threonine-protein kinase pim-12.7.11.10.447
3ddqRRCCyclin-dependent kinase 22.7.11.220.447
3ezrEZRCyclin-dependent kinase 22.7.11.220.447
3vw6IM6Mitogen-activated protein kinase kinase kinase 52.7.11.250.447
4bcmT7ZCyclin-dependent kinase 22.7.11.220.447
4g6oE28Mitogen-activated protein kinase 12.7.11.240.447
4l7f1V5Mitogen-activated protein kinase 82.7.11.240.447
4mf129YTyrosine-protein kinase ITK/TSK2.7.10.20.447
1daz0Q4Gag-Pol polyprotein3.4.23.160.446
1hosPHPGag-Pol polyprotein/0.446
1mokFAD2-oxopropyl-CoM reductase, carboxylating1.8.1.50.446
1pxoCK7Cyclin-dependent kinase 22.7.11.220.446
1xdpATPPolyphosphate kinase/0.446
1zp9ATPRIO-type serine/threonine-protein kinase Rio12.7.11.10.446
2ekaSAHDiphthine synthase/0.446
2exmZIPCyclin-dependent kinase 22.7.11.220.446
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.446
2yac937Serine/threonine-protein kinase PLK12.7.11.210.446
3eljGS7Mitogen-activated protein kinase 82.7.11.240.446
3k3ePDBHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.446
3lxpIZANon-receptor tyrosine-protein kinase TYK22.7.10.20.446
3ofm4B0Casein kinase II subunit alpha'2.7.11.10.446
3qqhX0ACyclin-dependent kinase 22.7.11.220.446
3w551FMMitogen-activated protein kinase 12.7.11.240.446
4lyn1YGCyclin-dependent kinase 22.7.11.220.446
4o0sADNAurora kinase A2.7.11.10.446
2bkzSBCCyclin-dependent kinase 22.7.11.220.445
2ds11CDCyclin-dependent kinase 22.7.11.220.445
2dxvSAHDiphthine synthase/0.445
2g263LGRenin3.4.23.150.445
2p3c3TLProtease/0.445
2p6kSAHDiphthine synthase/0.445
3a3gDLZLumazine protein/0.445
3at4CCKCasein kinase II subunit alpha2.7.11.10.445
3litE15Protease/0.445
3nwq2NCGag-Pol polyprotein3.4.23.160.445
3pxkPXKFocal adhesion kinase 12.7.10.20.445
3t1tGDPProbable gliding protein mglA/0.445
4bieIE6Mitogen-activated protein kinase kinase kinase 52.7.11.250.445
4e93GUITyrosine-protein kinase Fes/Fps2.7.10.20.445
4ifcADPSerine/threonine-protein kinase PRP4 homolog2.7.11.10.445
4jayFADUDP-N-acetylenolpyruvoylglucosamine reductase/0.445
4mcb21WtRNA (guanine-N(1)-)-methyltransferase2.1.1.2280.445
5cnnANPEpidermal growth factor receptor2.7.10.10.445
1ad5ANPTyrosine-protein kinase HCK2.7.10.20.444
1rekB8LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.444
1u54ACPActivated CDC42 kinase 1/0.444
2egbSAHDiphthine synthase/0.444
2oxtSAMGenome polyprotein/0.444
2p3a3TLPol protein/0.444
2pvnP63Casein kinase II subunit alpha2.7.11.10.444
2uy0HV1Gag-Pol polyprotein3.4.23.160.444
2wedPP6Penicillopepsin-13.4.23.200.444
2xhd7T9Glutamate receptor 2/0.444
3ambVX6cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.444
3cy2MB9Serine/threonine-protein kinase pim-12.7.11.10.444
3nunJMZ3-phosphoinositide-dependent protein kinase 12.7.11.10.444
3oxv478Gag-Pol polyprotein3.4.23.160.444
3qpjN4IGag-Pol polyprotein3.4.23.160.444
3qx2X63Cyclin-dependent kinase 22.7.11.220.444
3qzhX69Cyclin-dependent kinase 22.7.11.220.444
4acg6LQGlycogen synthase kinase-3 beta2.7.11.260.444
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.444
4e4n0NLTyrosine-protein kinase JAK1/0.444
4fg8ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.444
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.444
4qgiROCGag-Pol polyprotein3.4.23.160.444
2ccu2D9Heat shock protein HSP 90-alpha/0.443
2i0y5CNMacrophage colony-stimulating factor 1 receptor2.7.10.10.443
2iw84SPCyclin-dependent kinase 22.7.11.220.443
2pe15173-phosphoinositide-dependent protein kinase 12.7.11.10.443
2w05FRTCyclin-dependent kinase 22.7.11.220.443
2z2w770Wee1-like protein kinase2.7.10.20.443
3lltANPProtein serine/threonine kinase-1/0.443
3nwxKVSGag-Pol polyprotein3.4.23.160.443
3rm618ZCyclin-dependent kinase 22.7.11.220.443
3zdu38RCyclin-dependent kinase-like 32.7.11.220.443
4b99R4LMitogen-activated protein kinase 72.7.11.240.443
4btjADPTau-tubulin kinase 12.7.11.10.443
4dgnLU2Casein kinase II subunit alpha2.7.11.10.443
4eok4SPCyclin-dependent kinase 22.7.11.220.443
4hyh1AMSerine/threonine-protein kinase Chk12.7.11.10.443
4ii5ADPCyclin-dependent kinase 22.7.11.220.443
1drhNAPDihydrofolate reductase1.5.1.30.442
1me6IVSPlasmepsin-23.4.23.390.442
1q8yADPSerine/threonine-protein kinase SKY12.7.11.10.442
1rfuADPPyridoxal kinase2.7.1.350.442
1t7i017Gag-Pol polyprotein3.4.23.160.442
2a4lRRCCyclin-dependent kinase 22.7.11.220.442
2dwbANPAurora kinase A2.7.11.10.442
2r3p3SCCyclin-dependent kinase 22.7.11.220.442
3jswJARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.442
3oibFDAPutative acyl-CoA dehydrogenase/0.442
3qihNI7Gag-Pol polyprotein3.4.23.160.442
3r1yX76Cyclin-dependent kinase 22.7.11.220.442
4anwO92Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
4ccbOFGALK tyrosine kinase receptor2.7.10.10.442
4k4p3TLGag-Pol polyprotein/0.442
4ks7X4ZSerine/threonine-protein kinase PAK 62.7.11.10.442
4lopSB4Mitogen-activated protein kinase 14/0.442
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.442
1pnvTYDdTDP-epi-vancosaminyltransferase2.4.1.3110.441
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.441
2uznC96Cyclin-dependent kinase 22.7.11.220.441
2x4f16XMyosin light chain kinase family member 42.7.11.10.441
3a6rFMNFMN-binding protein/0.441
3amaSKEcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.441
3k5uPFQAurora kinase A2.7.11.10.441
3pm4F5NEndothiapepsin3.4.23.220.441
3pmy41LEndothiapepsin3.4.23.220.441
4iwd1JCHepatocyte growth factor receptor2.7.10.10.441
4ix6ADPUncharacterized protein/0.441
4lrjANPUncharacterized protein/0.441
4y93746Tyrosine-protein kinase/0.441
1m0b0ZQGag-Pol polyprotein3.4.23.160.440
1q3wATUGlycogen synthase kinase-3 beta2.7.11.260.440
1q41IXMGlycogen synthase kinase-3 beta2.7.11.260.440
1vyzN5BCyclin-dependent kinase 22.7.11.220.440
2c54NADGDP-mannose 3,5-epimerase5.1.3.180.440
2cciATPCyclin-dependent kinase 22.7.11.220.440
2f8g017Gag-Pol polyprotein3.4.23.160.440
2hunNAD336aa long hypothetical dTDP-glucose 4,6-dehydratase/0.440
2hydADPPutative multidrug export ATP-binding/permease protein SAV18663.6.30.440
2jcvNDP1-deoxy-D-xylulose 5-phosphate reductoisomerase/0.440
2p2xSAHDiphthine synthase/0.440
2r3fSC8Cyclin-dependent kinase 22.7.11.220.440
3hrcATP3-phosphoinositide-dependent protein kinase 12.7.11.10.440
3ijoB4DGlutamate receptor 2/0.440
3roy22ZCyclin-dependent kinase 22.7.11.220.440
3u9eCOALmo1369 protein/0.440
4anv751Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
4dpuAGSMevalonate diphosphate decarboxylase/0.440
4f650S9Fibroblast growth factor receptor 1/0.440
4fkpLS5Cyclin-dependent kinase 22.7.11.220.440
4njsG08Protease/0.440
4pl4ADPSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.440
4rqkATP3-phosphoinositide-dependent protein kinase 12.7.11.10.440
5e92ANPTGF-beta receptor type-22.7.11.300.440