sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3ffp | LC1 | Carbonic anhydrase 2 | 4.2.1.1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3ffp | LC1 | Carbonic anhydrase 2 | 4.2.1.1 | 1.000 | |
| 4kni | E1E | Carbonic anhydrase 2 | 4.2.1.1 | 0.823 | |
| 1if6 | FBU | Carbonic anhydrase 2 | 4.2.1.1 | 0.816 | |
| 3sbi | E90 | Carbonic anhydrase 2 | 4.2.1.1 | 0.816 | |
| 1g52 | F2B | Carbonic anhydrase 2 | 4.2.1.1 | 0.806 | |
| 3eft | 3BS | Carbonic anhydrase 2 | 4.2.1.1 | 0.777 | |
| 2eu3 | FF3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.774 | |
| 1oq5 | CEL | Carbonic anhydrase 2 | 4.2.1.1 | 0.772 | |
| 3m2n | J74 | Carbonic anhydrase 2 | 4.2.1.1 | 0.761 | |
| 3nb5 | R21 | Carbonic anhydrase 2 | 4.2.1.1 | 0.761 | |
| 3b4f | TUO | Carbonic anhydrase 2 | 4.2.1.1 | 0.754 | |
| 1zsb | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.752 | |
| 3s8x | E59 | Carbonic anhydrase 2 | 4.2.1.1 | 0.748 | |
| 2pow | I7C | Carbonic anhydrase 2 | 4.2.1.1 | 0.728 | |
| 1g54 | FFB | Carbonic anhydrase 2 | 4.2.1.1 | 0.727 | |
| 2weh | FB1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.724 | |
| 4itp | 1GD | Carbonic anhydrase 2 | 4.2.1.1 | 0.718 | |
| 4knj | E1F | Carbonic anhydrase 2 | 4.2.1.1 | 0.717 | |
| 3m5e | JDR | Carbonic anhydrase 2 | 4.2.1.1 | 0.714 | |
| 3k2f | NKX | Carbonic anhydrase 2 | 4.2.1.1 | 0.700 | |
| 3dd8 | 2C7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.697 | |
| 1cnw | EG1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.692 | |
| 2x7t | WZB | Carbonic anhydrase 2 | 4.2.1.1 | 0.692 | |
| 3oik | WZB | Carbonic anhydrase 2 | 4.2.1.1 | 0.692 | |
| 1g45 | FSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.691 | |
| 3m40 | J45 | Carbonic anhydrase 2 | 4.2.1.1 | 0.690 | |
| 2h15 | B19 | Carbonic anhydrase 2 | 4.2.1.1 | 0.689 | |
| 3mna | DWH | Carbonic anhydrase 2 | 4.2.1.1 | 0.689 | |
| 3qyk | IE2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.685 | |
| 3hku | TOR | Carbonic anhydrase 2 | 4.2.1.1 | 0.684 | |
| 3n0n | P9B | Carbonic anhydrase 2 | 4.2.1.1 | 0.678 | |
| 1if4 | FBS | Carbonic anhydrase 2 | 4.2.1.1 | 0.677 | |
| 1kwr | SG2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.677 | |
| 3mmf | D9H | Carbonic anhydrase 2 | 4.2.1.1 | 0.677 | |
| 3po6 | DT9 | Carbonic anhydrase 2 | 4.2.1.1 | 0.677 | |
| 3mhi | J90 | Carbonic anhydrase 2 | 4.2.1.1 | 0.676 | |
| 1g4j | FFB | Carbonic anhydrase 2 | 4.2.1.1 | 0.675 | |
| 1kwq | SG1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.675 | |
| 3f4x | KLT | Carbonic anhydrase 2 | 4.2.1.1 | 0.675 | |
| 3sbh | E65 | Carbonic anhydrase 2 | 4.2.1.1 | 0.675 | |
| 1bnm | AL8 | Carbonic anhydrase 2 | 4.2.1.1 | 0.670 | |
| 1okl | MNS | Carbonic anhydrase 2 | 4.2.1.1 | 0.669 | |
| 1i8z | INL | Carbonic anhydrase 2 | 4.2.1.1 | 0.668 | |
| 3dcs | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.668 | |
| 1if7 | SBR | Carbonic anhydrase 2 | 4.2.1.1 | 0.660 | |
| 3mhl | J71 | Carbonic anhydrase 2 | 4.2.1.1 | 0.657 | |
| 3oys | OYS | Carbonic anhydrase 2 | 4.2.1.1 | 0.654 | |
| 4mo8 | 2VQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.651 | |
| 3daz | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.650 | |
| 4kap | 1QV | Carbonic anhydrase 2 | 4.2.1.1 | 0.650 | |
| 1i9n | IOA | Carbonic anhydrase 2 | 4.2.1.1 | 0.649 | |
| 3mho | J43 | Carbonic anhydrase 2 | 4.2.1.1 | 0.649 | |
| 1bn4 | AL9 | Carbonic anhydrase 2 | 4.2.1.1 | 0.648 | |
| 3t84 | SG6 | Carbonic anhydrase 2 | 4.2.1.1 | 0.646 | |
| 5flt | VJJ | Carbonic anhydrase 2 | 4.2.1.1 | 0.646 | |
| 1okn | STB | Carbonic anhydrase 2 | 4.2.1.1 | 0.645 | |
| 2weg | FBV | Carbonic anhydrase 2 | 4.2.1.1 | 0.645 | |
| 3oim | VZ5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.645 | |
| 4k13 | ETS | Carbonic anhydrase 2 | 4.2.1.1 | 0.645 | |
| 1i90 | INM | Carbonic anhydrase 2 | 4.2.1.1 | 0.644 | |
| 1a42 | BZU | Carbonic anhydrase 2 | 4.2.1.1 | 0.643 | |
| 3mzc | S6I | Carbonic anhydrase 2 | 4.2.1.1 | 0.643 | |
| 3t82 | SG4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.642 | |
| 3t85 | SG7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.642 | |
| 3ni5 | C1H | Carbonic anhydrase 2 | 4.2.1.1 | 0.641 | |
| 1eou | SMS | Carbonic anhydrase 2 | 4.2.1.1 | 0.638 | |
| 1ttm | 667 | Carbonic anhydrase 2 | 4.2.1.1 | 0.636 | |
| 4m2v | BZ1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.636 | |
| 2weo | FBW | Carbonic anhydrase 2 | 4.2.1.1 | 0.634 | |
| 1bnv | AL7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.633 | |
| 1bnn | AL1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.629 | |
| 1cny | EG3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.628 | |
| 1yda | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.628 | |
| 4ito | MPX | Carbonic anhydrase 2 | 4.2.1.1 | 0.628 | |
| 3d8w | D8W | Carbonic anhydrase 2 | 4.2.1.1 | 0.627 | |
| 3dd0 | EZL | Carbonic anhydrase 2 | 4.2.1.1 | 0.627 | |
| 4ilx | 1EZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.626 | |
| 1xpz | 4TZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.625 | |
| 3ml2 | SU0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.625 | |
| 3oy0 | OY0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.624 | |
| 1i91 | INQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.623 | |
| 2wej | FB2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.622 | |
| 3myq | E27 | Carbonic anhydrase 2 | 4.2.1.1 | 0.622 | |
| 4pxx | CHD | Carbonic anhydrase 2 | 4.2.1.1 | 0.622 | |
| 1bn1 | AL5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.618 | |
| 1okm | SAB | Carbonic anhydrase 2 | 4.2.1.1 | 0.616 | |
| 3n3j | WWV | Carbonic anhydrase 2 | 4.2.1.1 | 0.616 | |
| 4n16 | CHD | Carbonic anhydrase 2 | 4.2.1.1 | 0.613 | |
| 1bn3 | AL6 | Carbonic anhydrase 2 | 4.2.1.1 | 0.612 | |
| 2wd2 | MS5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.610 | |
| 3d9z | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.608 | |
| 2h4n | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.605 | |
| 3kig | DA4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.602 | |
| 3dc3 | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.600 | |
| 3mhc | ARZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.600 | |
| 1if5 | FBT | Carbonic anhydrase 2 | 4.2.1.1 | 0.595 | |
| 1g4o | BSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.594 | |
| 3n4b | WWZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.594 | |
| 4k0t | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.589 | |
| 3dcc | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.586 | |
| 3l14 | I7B | Carbonic anhydrase 2 | 4.2.1.1 | 0.586 | |
| 4kp8 | E1G | Carbonic anhydrase 12 | 4.2.1.1 | 0.586 | |
| 1cil | ETS | Carbonic anhydrase 2 | 4.2.1.1 | 0.581 | |
| 1bnw | TPD | Carbonic anhydrase 2 | 4.2.1.1 | 0.580 | |
| 3mdz | EZL | Carbonic anhydrase 7 | 4.2.1.1 | 0.580 | |
| 4kp5 | E1F | Carbonic anhydrase 12 | 4.2.1.1 | 0.576 | |
| 1jd0 | AZM | Carbonic anhydrase 12 | 4.2.1.1 | 0.573 | |
| 4ht2 | V50 | Carbonic anhydrase 12 | 4.2.1.1 | 0.573 | |
| 4bf1 | 9FK | Carbonic anhydrase 2 | 4.2.1.1 | 0.571 | |
| 3igp | DT7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.570 | |
| 3bl1 | BL1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.566 | |
| 2x7u | WZA | Carbonic anhydrase 2 | 4.2.1.1 | 0.565 | |
| 3v2j | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.565 | |
| 4knm | E1E | Carbonic anhydrase 13 | 4.2.1.1 | 0.564 | |
| 3p5l | IT5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.560 | |
| 3znc | BZ1 | Carbonic anhydrase 4 | 4.2.1.1 | 0.554 | |
| 1i9q | IOF | Carbonic anhydrase 2 | 4.2.1.1 | 0.552 | |
| 3n2p | AYX | Carbonic anhydrase 2 | 4.2.1.1 | 0.548 | |
| 3oyq | OYQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.548 | |
| 3dcw | EZL | Carbonic anhydrase 2 | 4.2.1.1 | 0.547 | |
| 3f7u | AG4 | Carbonic anhydrase 4 | 4.2.1.1 | 0.541 | |
| 4xiw | AZM | Carbonic anhydrase, alpha type | / | 0.535 | |
| 3dbu | D8W | Carbonic anhydrase 2 | 4.2.1.1 | 0.531 | |
| 2q1q | OSP | Carbonic anhydrase 2 | 4.2.1.1 | 0.530 | |
| 4lu3 | AZM | Carbonic anhydrase 14 | 4.2.1.1 | 0.524 | |
| 1bnu | AL3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.523 | |
| 3rz8 | RZ8 | Carbonic anhydrase 2 | 4.2.1.1 | 0.521 | |
| 4dz7 | D02 | Carbonic anhydrase 2 | 4.2.1.1 | 0.521 | |
| 4x5s | AZM | Carbonic anhydrase (Carbonate dehydratase) | / | 0.520 | |
| 3f7b | AG5 | Carbonic anhydrase 4 | 4.2.1.1 | 0.514 | |
| 4uov | AZM | Carbonate dehydratase | / | 0.512 | |
| 1rj6 | AZM | Carbonic anhydrase 14 | 4.2.1.1 | 0.511 | |
| 4k0z | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.510 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.508 | |
| 1i9p | IOE | Carbonic anhydrase 2 | 4.2.1.1 | 0.507 | |
| 4hu1 | V13 | Carbonic anhydrase 13 | 4.2.1.1 | 0.507 | |
| 3fw3 | ETS | Carbonic anhydrase 4 | 4.2.1.1 | 0.505 | |
| 2q7o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.498 | |
| 1cnx | EG2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.496 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.495 | |
| 2yq9 | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.495 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.493 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.493 | |
| 4boe | CLR | Japanin | / | 0.487 | |
| 2d29 | FAD | Acyl-CoA dehydrogenase | / | 0.486 | |
| 1rsz | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.484 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.484 | |
| 4giu | 636 | Anthranilate phosphoribosyltransferase | / | 0.484 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.483 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.483 | |
| 1dmy | AZM | Carbonic anhydrase 5A, mitochondrial | 4.2.1.1 | 0.482 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.482 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.482 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.482 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.481 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.481 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.480 | |
| 1i5r | HYC | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.479 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.479 | |
| 4p9d | TMP | Deoxycytidylate deaminase | / | 0.479 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.478 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.478 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.478 | |
| 4iae | 1DX | Alr2278 protein | / | 0.478 | |
| 5fl4 | 9FK | Carbonic anhydrase 9 | 4.2.1.1 | 0.478 | |
| 1kp2 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.477 | |
| 1mxf | MTX | Putative pteridine reductase 2 | / | 0.476 | |
| 2c9z | QUE | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.476 | |
| 3zbs | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.476 | |
| 1gpd | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.475 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.475 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.475 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.474 | |
| 3zvm | ADP | Bifunctional polynucleotide phosphatase/kinase | 2.7.1.78 | 0.474 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.473 | |
| 3l6j | Z90 | Alr2278 protein | / | 0.473 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.473 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.473 | |
| 4knn | E1F | Carbonic anhydrase 13 | 4.2.1.1 | 0.473 | |
| 1kh3 | ANP | Argininosuccinate synthase | / | 0.472 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.472 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.472 | |
| 2z1q | FAD | Acyl-CoA dehydrogenase | / | 0.472 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.472 | |
| 3qj0 | QI3 | Botulinum neurotoxin type A | 3.4.24.69 | 0.472 | |
| 3sl2 | ATP | Sensor histidine kinase WalK | / | 0.472 | |
| 3w6h | AZM | Carbonic anhydrase 1 | 4.2.1.1 | 0.472 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.471 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.471 | |
| 3k8q | 22A | Purine nucleoside phosphorylase | 2.4.2.1 | 0.471 | |
| 3otb | DGT | Probable tRNA(His) guanylyltransferase | 2.7.7.79 | 0.471 | |
| 4rvg | TYD | D-mycarose 3-C-methyltransferase | / | 0.471 | |
| 1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.469 | |
| 1xva | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.469 | |
| 4drj | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.468 | |
| 4drj | RAP | Peptidyl-prolyl cis-trans isomerase FKBP4 | 5.2.1.8 | 0.468 | |
| 4rls | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.467 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.466 | |
| 2bjf | DXC | Choloylglycine hydrolase | 3.5.1.24 | 0.466 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.466 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.466 | |
| 3lxe | TOR | Carbonic anhydrase 1 | 4.2.1.1 | 0.466 | |
| 4r1f | ADP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.466 | |
| 2x0i | NAI | Malate dehydrogenase | / | 0.465 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.465 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.465 | |
| 1cf3 | FAD | Glucose oxidase | 1.1.3.4 | 0.464 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.464 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.464 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.464 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.464 | |
| 4bzo | 676 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.464 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.464 | |
| 1w19 | T5P | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.463 | |
| 3fr2 | 8CA | Fatty acid-binding protein, adipocyte | / | 0.463 | |
| 4zj8 | SUV | Orexin receptor type 1 | / | 0.463 | |
| 1nsg | RAD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.462 | |
| 1nsg | RAD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.462 | |
| 1x1a | SAM | C-20 methyltransferase | / | 0.462 | |
| 3jyp | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.462 | |
| 3qi4 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.462 | |
| 4a84 | DXC | Major pollen allergen Bet v 1-A | / | 0.462 | |
| 4ms1 | 381 | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.462 | |
| 4v12 | POG | MaoC like domain protein | / | 0.462 | |
| 2a59 | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.461 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.461 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.460 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.460 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.460 | |
| 3uu1 | 14B | Anthranilate phosphoribosyltransferase | / | 0.460 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.460 | |
| 1qoq | IGP | Tryptophan synthase alpha chain | / | 0.459 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.459 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.459 | |
| 1akb | PPD | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.458 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 1yw8 | A75 | Methionine aminopeptidase 2 | / | 0.458 | |
| 2e9a | B28 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.458 | |
| 3aos | JH2 | Hemolymph juvenile hormone binding protein | / | 0.458 | |
| 4b12 | C23 | Glycylpeptide N-tetradecanoyltransferase | / | 0.458 | |
| 1ps9 | MDE | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.457 | |
| 2rhg | IGP | Tryptophan synthase alpha chain | / | 0.457 | |
| 4oe4 | NAD | Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial | 1.2.1.88 | 0.457 | |
| 1c7o | PPG | Hemolysin | / | 0.456 | |
| 2cv2 | GSU | Glutamate--tRNA ligase | 6.1.1.17 | 0.456 | |
| 2g1o | 2IG | Renin | 3.4.23.15 | 0.456 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.456 | |
| 3fp0 | FP0 | 15-O-acetyltransferase | / | 0.456 | |
| 3jun | AKD | Phenazine biosynthesis protein A/B | / | 0.456 | |
| 3upk | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.456 | |
| 4c77 | N01 | Phenylacetone monooxygenase | 1.14.13.92 | 0.456 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.456 | |
| 4n1f | CZH | Obelin | / | 0.456 | |
| 1s64 | 778 | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.455 | |
| 3bgs | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.455 | |
| 4e2y | JHZ | Methyltransferase | / | 0.455 | |
| 4euf | NAD | Trans-2-enoyl-CoA reductase [NADH] | / | 0.455 | |
| 4wdg | A2P | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.455 | |
| 1h74 | ADP | Homoserine kinase | 2.7.1.39 | 0.454 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 1jtv | TES | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.454 | |
| 1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.454 | |
| 2lfo | GCH | Fatty acid-binding protein, liver | / | 0.454 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.454 | |
| 4a31 | 2CB | Glycylpeptide N-tetradecanoyltransferase | / | 0.454 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.454 | |
| 4iah | 1DX | Alr2278 protein | / | 0.454 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.454 | |
| 1a5b | IGP | Tryptophan synthase alpha chain | / | 0.453 | |
| 1dig | L37 | C-1-tetrahydrofolate synthase, cytoplasmic | 1.5.1.5 | 0.453 | |
| 1kyv | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.453 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.453 | |
| 3bxx | QUE | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.453 | |
| 3fr4 | F8A | Fatty acid-binding protein, adipocyte | / | 0.453 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.453 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.453 | |
| 4gv4 | MEJ | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.453 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.452 | |
| 1rft | PXM | Pyridoxal kinase | 2.7.1.35 | 0.452 | |
| 1xl8 | 152 | Peroxisomal carnitine O-octanoyltransferase | 2.3.1.137 | 0.452 | |
| 1ygj | RMC | Pyridoxal kinase | 2.7.1.35 | 0.452 | |
| 1zdw | FLV | Prenyltransferase | / | 0.452 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.452 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.452 | |
| 3mdd | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.452 | |
| 4a87 | NAR | Major pollen allergen Bet v 1-A | / | 0.452 | |
| 4xo7 | ASD | Aldo-keto reductase family 1 member C2 | / | 0.452 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.451 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.451 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.451 | |
| 2pau | D5M | 5'-deoxynucleotidase YfbR | / | 0.451 | |
| 3std | MQ0 | Scytalone dehydratase | 4.2.1.94 | 0.451 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.451 | |
| 1e3e | NAI | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.450 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.450 | |
| 2r0c | FAD | Putative FAD-monooxygenase | / | 0.450 | |
| 2vat | COA | Acetyl-CoA--deacetylcephalosporin C acetyltransferase | 2.3.1.175 | 0.450 | |
| 3ag6 | PAJ | Pantothenate synthetase | / | 0.450 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.450 | |
| 3tvq | DQH | Multifunctional cyclase-dehydratase-3-O-methyl transferase TcmN | 2.1.1 | 0.450 | |
| 4e0u | 0MV | Cyclic dipeptide N-prenyltransferase | / | 0.450 | |
| 4loi | 1YC | Stimulator of interferon genes protein | / | 0.450 | |
| 4nie | NBH | Nuclear receptor ROR-gamma | / | 0.450 | |
| 1eq2 | NAP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.449 | |
| 1hku | NAD | C-terminal-binding protein 1 | 1.1.1 | 0.449 | |
| 1wxj | IPL | Tryptophan synthase alpha chain | / | 0.449 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.449 | |
| 2bxo | OPB | Serum albumin | / | 0.449 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 3dsz | LIZ | Neutrophil gelatinase-associated lipocalin | / | 0.449 | |
| 3k9u | ACO | Spermidine N(1)-acetyltransferase | / | 0.449 | |
| 3t3r | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.449 | |
| 3u2m | FAD | FAD-linked sulfhydryl oxidase ALR | 1.8.3.2 | 0.449 | |
| 4ead | 0NP | Thymidine phosphorylase | 2.4.2.4 | 0.449 | |
| 4ejv | LCL | Transcriptional regulator TcaR | / | 0.449 | |
| 4h0v | NAD | Iota toxin component Ia | / | 0.449 | |
| 7std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.449 | |
| 2rh9 | IGP | Tryptophan synthase alpha chain | / | 0.448 | |
| 2xve | FAD | Putative flavin-containing monooxygenase | / | 0.448 | |
| 3iwj | NAD | Aminoaldehyde dehydrogenase | / | 0.448 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
| 4mr7 | 2BV | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.448 | |
| 4n1g | CEI | Obelin | / | 0.448 | |
| 4rh1 | 0TT | Spore photoproduct lyase | / | 0.448 | |
| 5eio | NAP | [LysW]-L-2-aminoadipate 6-phosphate reductase | / | 0.448 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.447 | |
| 2a1t | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.447 | |
| 2abj | CBC | Branched-chain-amino-acid aminotransferase, cytosolic | 2.6.1.42 | 0.447 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.447 | |
| 2iyf | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.447 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.447 | |
| 3ruc | UD2 | UDP-N-acetylglucosamine 4-epimerase | / | 0.447 | |
| 4an4 | DUD | Putative glycosyl transferase | / | 0.447 | |
| 4o4i | ACP | Tubulin tyrosine ligase | / | 0.447 | |
| 4r81 | FMN | Predicted NADH dehydrogenase | / | 0.447 | |
| 4x7v | MIV | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.447 | |
| 5kgh | ACO | Predicted acetyltransferase | / | 0.447 | |
| 5std | UNN | Scytalone dehydratase | 4.2.1.94 | 0.447 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.446 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.446 | |
| 1ygk | RRC | Pyridoxal kinase | 2.7.1.35 | 0.446 | |
| 2g0n | GDP | Ras-related C3 botulinum toxin substrate 3 | / | 0.446 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.446 | |
| 3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.446 | |
| 3qsa | TA7 | Anthranilate phosphoribosyltransferase | / | 0.446 | |
| 4eb5 | PLP | Cysteine desulfurase IscS 2 | / | 0.446 | |
| 4fxy | 0W2 | Neurolysin, mitochondrial | 3.4.24.16 | 0.446 | |
| 4k36 | SAM | Anaerobic sulfatase-maturating enzyme | 1.8.98 | 0.446 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.446 | |
| 1ivs | VAA | Valine--tRNA ligase | 6.1.1.9 | 0.445 | |
| 2fap | RAD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.445 | |
| 2fap | RAD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.445 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.445 | |
| 3smk | CW7 | 14-3-3 protein sigma | / | 0.445 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.445 | |
| 4b66 | NAP | L-ornithine N(5)-monooxygenase | / | 0.445 | |
| 4jlm | 1NN | Deoxycytidine kinase | 2.7.1.74 | 0.445 | |
| 4jqh | 1MF | Alr2278 protein | / | 0.445 | |
| 4kln | AGS | Transitional endoplasmic reticulum ATPase | 3.6.4.6 | 0.445 | |
| 5kwv | ANP | Pantothenate synthetase | / | 0.445 | |
| 1euy | QSI | Glutamine--tRNA ligase | 6.1.1.18 | 0.444 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1qy2 | IPZ | Major urinary protein 1 | / | 0.444 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.444 | |
| 1rt9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.444 | |
| 2a0w | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.444 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.444 | |
| 2g1y | 5IG | Renin | 3.4.23.15 | 0.444 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.444 | |
| 2ga2 | A19 | Methionine aminopeptidase 2 | / | 0.444 | |
| 2i4p | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.444 | |
| 2iya | ZIO | Oleandomycin glycosyltransferase | / | 0.444 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.444 | |
| 2oaz | I96 | Methionine aminopeptidase 2 | / | 0.444 | |
| 2pnc | CLU | Primary amine oxidase, liver isozyme | / | 0.444 | |
| 2r59 | PH0 | Leukotriene A-4 hydrolase | 3.3.2.6 | 0.444 | |
| 3aty | FMN | Prostaglandin F2a synthase | / | 0.444 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.444 | |
| 3zhs | TD6 | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.444 | |
| 4iax | LIZ | Neutrophil gelatinase-associated lipocalin | / | 0.444 | |
| 4rvf | TYD | D-mycarose 3-C-methyltransferase | / | 0.444 | |
| 4xrb | NDP | Possible bifunctional enzyme riboflavin biosynthesis protein RibD: diaminohydroxyphosphoribosylaminopyrimidine deaminase (Riboflavin-specific deaminase) + 5-amino-6-(5-phosphoribosylamino)uracil reduc | / | 0.444 | |
| 1rx0 | FAD | Isobutyryl-CoA dehydrogenase, mitochondrial | 1.3.99 | 0.443 | |
| 1vce | SAH | Diphthine synthase | / | 0.443 | |
| 1yw9 | A84 | Methionine aminopeptidase 2 | / | 0.443 | |
| 2ft9 | CHD | Fatty acid-binding protein 2, liver | / | 0.443 | |
| 2q85 | 973 | UDP-N-acetylenolpyruvoylglucosamine reductase | 1.3.1.98 | 0.443 | |
| 2v2z | CDM | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.443 | |
| 3c35 | KAI | Glutamate receptor ionotropic, kainate 1 | / | 0.443 | |
| 3eon | 341 | Glutaryl-CoA dehydrogenase | / | 0.443 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.443 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.443 | |
| 3mpj | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.443 | |
| 3qw4 | U5P | Orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative | / | 0.443 | |
| 3vyf | VYF | Renin | 3.4.23.15 | 0.443 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 4dpt | AGS | Mevalonate diphosphate decarboxylase | / | 0.443 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 4ge7 | 0K5 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.443 | |
| 4kto | FAD | Putative isovaleryl-CoA dehydrogenase protein | / | 0.443 | |
| 4l6g | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.443 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 1cq8 | PY6 | Aspartate aminotransferase | 2.6.1.1 | 0.442 | |
| 1egd | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.442 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 1yc1 | 4BC | Heat shock protein HSP 90-alpha | / | 0.442 | |
| 2g21 | L1B | Renin | 3.4.23.15 | 0.442 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.442 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.442 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 4bge | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 4iaw | LIZ | Neutrophil gelatinase-associated lipocalin | / | 0.442 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.442 | |
| 4tyq | AP5 | Adenylate kinase | / | 0.442 | |
| 1ejb | INJ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.441 | |
| 1qrs | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.441 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.441 | |
| 2g25 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.441 | |
| 2ivn | ANP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.441 | |
| 2pg0 | FAD | Acyl-CoA dehydrogenase | / | 0.441 | |
| 2std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.441 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 3pm1 | ET | HTH-type transcriptional regulator QacR | / | 0.441 | |
| 3qfa | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.441 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.441 | |
| 3zs7 | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.441 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.441 | |
| 4jxx | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.441 | |
| 4m9a | FDA | Acyl-CoA dehydrogenase | / | 0.441 | |
| 4uwm | FMN | 3,6-diketocamphane 1,6 monooxygenase | 1.14.13 | 0.441 | |
| 4xr9 | NAD | CalS8 | / | 0.441 | |
| 4yco | FMN | tRNA-dihydrouridine(16) synthase | / | 0.441 | |
| 1n75 | ATP | Glutamate--tRNA ligase | 6.1.1.17 | 0.440 | |
| 1qti | GNT | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 1szg | FNS | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.440 | |
| 2fon | FAD | Acyl-coenzyme A oxidase | / | 0.440 | |
| 2jj2 | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.440 | |
| 2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.440 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.440 | |
| 2r8v | ACO | Amino-acid acetyltransferase | / | 0.440 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.440 | |
| 2vn1 | FK5 | Peptidylprolyl isomerase | / | 0.440 | |
| 2xwe | AMF | Glucosylceramidase | 3.2.1.45 | 0.440 | |
| 2y1t | DUD | SPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS | 3.6.1.23 | 0.440 | |
| 2zvc | SAH | Precorrin-3 C17-methyltransferase | / | 0.440 | |
| 3e8x | NAP | BH1520 protein | / | 0.440 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.440 | |
| 4c3y | FAD | 3-ketosteroid dehydrogenase | / | 0.440 | |
| 4em4 | FAD | Coenzyme A disulfide reductase | / | 0.440 | |
| 4x7u | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.440 | |
| 5a01 | 12V | O-glycosyltransferase | / | 0.440 |