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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2rtmIMIStreptavidin

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
2rtmIMIStreptavidin/1.000
2rtlIMIStreptavidin/0.671
1srfMTBStreptavidin/0.606
2rtnIMIStreptavidin/0.597
1df8BTNStreptavidin/0.590
3ry2BTNStreptavidin/0.577
4bx7B4FStreptavidin/0.572
2rtfBTNStreptavidin/0.568
2rtqIMIStreptavidin/0.566
2izjBTNStreptavidin/0.563
2izkGLLStreptavidin/0.562
2izhBTNStreptavidin/0.559
1luqBTNStreptavidin/0.555
1sriDMBStreptavidin/0.554
1mk5BTNStreptavidin/0.547
1srgMHBStreptavidin/0.546
2fhnBNIAvidin-related protein 4/5/0.541
2rtoIMIStreptavidin/0.541
3t2wBTNAvidin/streptavidin/0.541
1lczBH7Streptavidin/0.540
1stpBTNStreptavidin/0.538
2y3fBTNStreptavidin/0.538
2rteBTNStreptavidin/0.535
1srjNABStreptavidin/0.534
1swtBTNStreptavidin/0.532
2rtrIMIStreptavidin/0.532
1srhMOBStreptavidin/0.530
4dneDTBStreptavidin/0.530
2izgBTNStreptavidin/0.529
3wyqBTNStreptavidin/0.527
4gdaBTNStreptavidin/0.526
1sreHABStreptavidin/0.524
2izfBTNStreptavidin/0.519
3wznBTNStreptavidin/0.519
1lcwSHMStreptavidin/0.518
2rtkGLLStreptavidin/0.518
3rdqDTBStreptavidin/0.518
1avdBTNAvidin/0.515
2rtdBTNStreptavidin/0.514
2rtgBTNStreptavidin/0.514
1rxhBNIStreptavidin/0.513
2izlIMIStreptavidin/0.512
1i9hBNIStreptavidin/0.511
2c4iBTNAvidin/0.511
2rtpIMIStreptavidin/0.511
2aviBTNAvidin/0.510
2fhlBNIAvidin-related protein 4/5/0.506
4z28BTNHoefavidin/0.506
1cjkFOKAdenylate cyclase type 2/0.504
1cjkFOKAdenylate cyclase type 5/0.504
2iziBTNStreptavidin/0.500
2y1oT26UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.500
1swnBTNStreptavidin/0.498
3nr4PYVAbscisic acid receptor PYL2/0.498
1culFOKAdenylate cyclase type 2/0.496
1culFOKAdenylate cyclase type 5/0.496
3zkyWT4Isopenicillin N synthase1.21.3.10.495
1klkPMDDihydrofolate reductase1.5.1.30.494
1oc1ASVIsopenicillin N synthase1.21.3.10.494
2vbpVB1Isopenicillin N synthase1.21.3.10.493
3gytDL4Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.493
3gyuDL7Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.492
4ly91YYGlucokinase regulatory protein/0.491
2jb4A14Isopenicillin N synthase1.21.3.10.490
4b1rITCTetracycline repressor protein class D/0.490
1hfqMOTDihydrofolate reductase1.5.1.30.489
3d84NDPDihydrofolate reductase1.5.1.30.489
1bk0ACVIsopenicillin N synthase1.21.3.10.488
1nqmBTNStreptavidin/0.488
1p8dCO1Oxysterols receptor LXR-beta/0.487
2uywBTNAvd protein/0.487
3kpzZNEVitamin D3 receptor/0.486
3up3XCAaceDAF-12/0.484
4bbxLKFcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.484
1y52BTNAvidin-related protein 4/5/0.483
1zklIBMHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A3.1.4.530.483
2a5c8DAAvidin/0.483
3uovFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.483
1tsxUMPThymidylate synthase/0.482
1hb1OCVIsopenicillin N synthase1.21.3.10.481
1kt6RTLRetinol-binding protein 4/0.481
2uxoTACHTH-type transcriptional regulator TtgR/0.481
2vbdV10Isopenicillin N synthase1.21.3.10.481
3zkuHCVIsopenicillin N synthase1.21.3.10.481
1sweBTNStreptavidin/0.480
1swpBTQStreptavidin/0.480
1swdBTNStreptavidin/0.479
2rtiGLLStreptavidin/0.479
2xysSY9Soluble acetylcholine receptor/0.479
1cjtFOKAdenylate cyclase type 2/0.478
1cjtFOKAdenylate cyclase type 5/0.478
1jtvTESEstradiol 17-beta-dehydrogenase 11.1.1.620.478
1n9mBTNStreptavidin/0.478
2bswCAOProbable acetyltransferase/0.478
2iviACWIsopenicillin N synthase1.21.3.10.478
2wsa646Glycylpeptide N-tetradecanoyltransferase/0.478
3u33FADPutative acyl-CoA dehydrogenase AidB1.3.990.478
1mrqSTRAldo-keto reductase family 1 member C1/0.477
1opmIYGPeptidyl-glycine alpha-amidating monooxygenase1.14.17.30.477
1swrBTNStreptavidin/0.477
2iodMYCDihydroflavonol 4-reductase1.1.1.2190.477
4h9753SDihydrofolate reductase1.5.1.30.477
4jx1CAHCamphor 5-monooxygenase1.14.15.10.477
5iqdGNPBifunctional AAC/APH2.3.10.477
1dr3TAPDihydrofolate reductase1.5.1.30.476
1rkgVD1Vitamin D3 receptor/0.476
3c0g3AMPeripheral plasma membrane protein CASK2.7.11.10.476
4bcsBTNAvidin-related protein 4/5/0.476
4bfuZVUPantothenate kinase2.7.1.330.476
1qiqACCIsopenicillin N synthase1.21.3.10.475
4pd6URINucleoside permease/0.475
1mepBTNStreptavidin/0.474
1upw444Oxysterols receptor LXR-beta/0.474
2hamC33Vitamin D3 receptor/0.474
2o7oDXTTetracycline repressor protein class D/0.474
5c6cCMPcGMP-dependent protein kinase 22.7.11.120.474
5fm7ADPRuvB-like helicase/0.474
2aqhNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.473
2zscBTNTamavidin2/0.473
3arvSAUChitinase A/0.473
3ew2BTNHypothetical conserved protein/0.473
3vf60H6Glucokinase2.7.1.20.473
1dr2TAPDihydrofolate reductase1.5.1.30.472
1jnrFADAdenylylsulfate reductase, subunit A (AprA)/0.472
3a783EVVitamin D3 receptor/0.472
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.471
1obnASVIsopenicillin N synthase1.21.3.10.471
2xveFADPutative flavin-containing monooxygenase/0.471
3e6t1A2Nitric oxide synthase, inducible1.14.13.390.471
3up0D7SaceDAF-12/0.471
4kxjP34Nucleoprotein/0.471
1dhfFOLDihydrofolate reductase1.5.1.30.470
1ie9VDXVitamin D3 receptor/0.470
2uz2BTNAvd protein/0.470
2y6fM9FIsopenicillin N synthase1.21.3.10.470
2zjwREFCasein kinase II subunit alpha2.7.11.10.470
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.470
5hbrCOAAcyl-CoA synthetase (NDP forming)/0.470
1hb3SCVIsopenicillin N synthase1.21.3.10.469
1o6qR17Squalene--hopene cyclase4.2.1.1290.469
2uagUMAUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.469
2vcmM11Isopenicillin N synthase1.21.3.10.469
2wo7ASVIsopenicillin N synthase1.21.3.10.469
2x7hPFNProstaglandin reductase 310.469
3byzH11Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.469
3lu8IQXSerum albumin/0.469
3um5CP6Bifunctional dihydrofolate reductase-thymidylate synthase/0.469
4b5nFMNNAD(P)H:flavin oxidoreductase Sye4/0.469
4m6l21VDihydrofolate reductase1.5.1.30.469
1mvtDTMDihydrofolate reductase1.5.1.30.468
5eccNAPDehydrofolate reductase type I/0.468
3qakUKAAdenosine receptor A2a/0.468
1nw5SAMModification methylase RsrI2.1.1.720.467
2j9lATPH(+)/Cl(-) exchange transporter 5/0.467
2qo4CHDFatty acid-binding protein 10-A, liver basic/0.467
1ndjBTNStreptavidin/0.466
1rk3VDXVitamin D3 receptor/0.466
1zdwFLVPrenyltransferase/0.466
2npfMOUElongation factor 2/0.466
3h3t16HCollagen type IV alpha-3-binding protein/0.466
3wypBSOStreptavidin/0.466
4cax646Glycylpeptide N-tetradecanoyltransferase2.3.1.970.466
4h9506UDihydrofolate reductase1.5.1.30.466
4u9zCOAAlpha-tubulin N-acetyltransferase 1/0.466
1nw6SFGModification methylase RsrI2.1.1.720.465
1ot7CHCBile acid receptor/0.465
1w06W05Isopenicillin N synthase1.21.3.10.465
2jfaRALEstrogen receptor/0.465
2oiqSTIProto-oncogene tyrosine-protein kinase Src2.7.10.20.465
3d4bDZDNAD-dependent protein deacetylase/0.465
3hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.465
4ap3FADSteroid monooxygenase/0.465
4dtiNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.465
4g20484Vitamin D3 receptor A/0.465
1cjuFOKAdenylate cyclase type 2/0.464
1cjuFOKAdenylate cyclase type 5/0.464
1db1VDXVitamin D3 receptor/0.464
1ie8KH1Vitamin D3 receptor/0.464
2po7CHDFerrochelatase, mitochondrial4.99.1.10.464
3hadNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.464
3vrvYSDVitamin D3 receptor/0.464
4c1iEH9cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.464
1pq944BOxysterols receptor LXR-beta/0.463
2belCBOCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.463
2pr2DG1Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.463
2zbaZBATrichothecene 3-O-acetyltransferase/0.463
3h3sH15Collagen type IV alpha-3-binding protein/0.463
3pg3DG7Mitogen-activated protein kinase 14/0.463
1r2jFADFkbI/0.462
1z6tADPApoptotic protease-activating factor 1/0.462
3c3xNAPEugenol synthase 11.1.1.3180.462
3och2MXDihydrofolate reductase1.5.1.30.462
3p8jFMNPentaerythritol tetranitrate reductase/0.462
4iaq2GM5-hydroxytryptamine receptor 1B/0.462
4wdb2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.462
1cjvFOKAdenylate cyclase type 2/0.461
1cjvFOKAdenylate cyclase type 5/0.461
2oegUPGUDP-glucose pyrophosphorylase/0.461
2y60M8FIsopenicillin N synthase1.21.3.10.461
3bi6396Wee1-like protein kinase2.7.10.20.461
3c1tMYCDihydroflavonol 4-reductase1.1.1.2190.461
3eblGA4Gibberellin receptor GID1/0.461
3jynNDPQuinone oxidoreductase/0.461
3v4tUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.461
4a2aATPCell division protein FtsA/0.461
4zzjCNANAD-dependent protein deacetylase sirtuin-13.5.10.461
5iqbGNPBifunctional AAC/APH2.3.10.461
1eg2MTAModification methylase RsrI2.1.1.720.460
1hvyD16Thymidylate synthase2.1.1.450.460
1n43BTNStreptavidin/0.460
2bfqAR6[Protein ADP-ribosylglutamate] hydrolase AF_15213.2.20.460
2fszOHTEstrogen receptor beta/0.460
3dheANDEstradiol 17-beta-dehydrogenase 11.1.1.620.460
3orfNADDihydropteridine reductase1.5.1.340.460
4g1z0VPVitamin D3 receptor A/0.460
4g8zTOPDihydrofolate reductase1.5.1.30.460
4hbm0Y7E3 ubiquitin-protein ligase Mdm26.3.20.460
3emlZMAAdenosine receptor A2a/0.460
1pd9CO4Dihydrofolate reductase1.5.1.30.459
1yc2NADNAD-dependent protein deacylase 2/0.459
2bu9HFVIsopenicillin N synthase1.21.3.10.459
2gqg1N1Tyrosine-protein kinase ABL12.7.10.20.459
2uxpCLMHTH-type transcriptional regulator TtgR/0.459
3fznD7KBenzoylformate decarboxylase4.1.1.70.459
3zw9NADPeroxisomal bifunctional enzyme1.1.1.350.459
4bquCLRJapanin/0.459
4ead0NPThymidine phosphorylase2.4.2.40.459
4u9yCOAAlpha-tubulin N-acetyltransferase 1/0.459
2nomDUTPoly(A) polymerase, putative/0.458
2o1xTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.458
3atzFMNProstaglandin F2a synthase/0.458
3hxbBD5Geranylgeranyl transferase type-2 subunit beta2.5.1.600.458
3sqxANPATP-dependent RNA helicase MSS116, mitochondrial3.6.4.130.458
4a2zVIQGlycylpeptide N-tetradecanoyltransferase/0.458
4dpy2P0Mevalonate diphosphate decarboxylase/0.458
1dr5NAPDihydrofolate reductase1.5.1.30.457
1drbMTXDihydrofolate reductase1.5.1.30.457
1gheACOAcetyltransferase2.3.10.457
1mvsDTMDihydrofolate reductase1.5.1.30.457
1qjfACSIsopenicillin N synthase1.21.3.10.457
2bikBI1Serine/threonine-protein kinase pim-12.7.11.10.457
2o7pNAPRiboflavin biosynthesis protein RibD/0.457
3gncQQQGlutaryl-CoA dehydrogenase/0.457
3nj0PYVAbscisic acid receptor PYL2/0.457
3vrwYS5Vitamin D3 receptor/0.457
4d9eLCSD-cysteine desulfhydrase/0.457
1gnwGTXGlutathione S-transferase F22.5.1.180.456
1ia3TQ5Dihydrofolate reductase1.5.1.30.456
1ot7IU5Bile acid receptor/0.456
1s19MC9Vitamin D3 receptor/0.456
1yhjR6CPyridoxal kinase2.7.1.350.456
2qo5CHDFatty acid-binding protein 10-A, liver basic/0.456
2rhrEMOPutative ketoacyl reductase1.3.10.456
3lfeZ84Mitogen-activated protein kinase 14/0.456
4ejn0R4RAC-alpha serine/threonine-protein kinase2.7.11.10.456
4hy6FJ1Heat shock protein HSP 90-alpha/0.456
4iarERM5-hydroxytryptamine receptor 1B/0.456
4jqh1MFAlr2278 protein/0.456
4l8u9AZSerum albumin/0.456
4pnmNU1Tankyrase-22.4.2.300.456
5gcnCOAHAT A1/0.456
5ifiPRXAcetyl-coenzyme A synthetase/0.456
5kf9COAPredicted acetyltransferase/0.456
1dduCB3Thymidylate synthase/0.455
1fp1HCCIsoliquiritigenin 2'-O-methyltransferase/0.455
1kt3RTLRetinol-binding protein 4/0.455
2fonFADAcyl-coenzyme A oxidase/0.455
2xtbKRMAdenosine kinase, putative/0.455
3o6o94MHeat shock protein 83/0.455
4eqsCOACoenzyme A disulfide reductase/0.455
4u2lSFDCholesterol oxidase1.1.3.60.455
1b2lNDCAlcohol dehydrogenase1.1.1.10.454
1fmlRTLRetinol dehydratase/0.454
1ojtFADDihydrolipoyl dehydrogenase/0.454
1sbrVIBPutative HMP/thiamine-binding protein YkoF/0.454
1uzwCDHIsopenicillin N synthase1.21.3.10.454
1vbiNADMalate/L-lactate dehydrogenase family protein/0.454
2j3jHC4NADPH-dependent oxidoreductase 2-alkenal reductase1.3.1.740.454
2jn3JN3Fatty acid-binding protein, liver/0.454
2uxhQUEHTH-type transcriptional regulator TtgR/0.454
2ykeYKEHeat shock protein HSP 90-alpha/0.454
2z9dFMNFMN-dependent NADH-azoreductase/0.454
3pjcPJCTyrosine-protein kinase JAK32.7.10.20.454
3q44D50M1 family aminopeptidase3.4.110.454
3sgy06WDihydrofolate reductase1.5.1.30.454
3w8wFADPutative FAD-dependent oxygenase EncM/0.454
4b5oACOAlpha-tubulin N-acetyltransferase 1/0.454
4bfxZVXPantothenate kinase2.7.1.330.454
4dpdUMPBifunctional dihydrofolate reductase-thymidylate synthase/0.454
4ge40KEKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.454
4hfr14MCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.454
4kak06UDihydrofolate reductase1.5.1.30.454
4mr61K0Bromodomain-containing protein 2/0.454
5e5h0T1Succinyl-CoA:acetate CoA-transferase/0.454
5h8tRTLRetinol-binding protein 1/0.454
5iua6DXAdenosine receptor A2a/0.454
1dhjMTXDihydrofolate reductase1.5.1.30.453
1ezfIN0Squalene synthase2.5.1.210.453
1zd9GDPADP-ribosylation factor-like protein 8A/0.453
2ph5NADHomospermidine synthase/0.453
2pk3A2RGDP-6-deoxy-D-mannose reductase/0.453
3br3ETHTH-type transcriptional regulator QacR/0.453
3gdpFAD(R)-mandelonitrile lyase 24.1.2.100.453
3n0hTOPDihydrofolate reductase1.5.1.30.453
3u9fCLMChloramphenicol acetyltransferase2.3.1.280.453
3v1uHXC3-oxoacyl-(Acyl-carrier-protein) reductase/0.453
4dpdDHFBifunctional dihydrofolate reductase-thymidylate synthase/0.453
4mryCEIObelin/0.453
5d1bTSNHistone deacetylase 83.5.1.980.453
1blzACVIsopenicillin N synthase1.21.3.10.452
1nc9IMIStreptavidin/0.452
1sdwIYTPeptidyl-glycine alpha-amidating monooxygenase1.14.17.30.452
1siqFADGlutaryl-CoA dehydrogenase, mitochondrial1.3.8.60.452
1udaUFGUDP-glucose 4-epimerase5.1.3.20.452
1vzdCB3Thymidylate synthase/0.452
2g8aUMPThymidylate synthase/0.452
2hb8MVDVitamin D3 receptor/0.452
2wufKEM4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase3.7.1.170.452
3ch6311Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.452
3ed1GA3Gibberellin receptor GID1/0.452
3irm1CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.452
4aosNAPSteroid monooxygenase/0.452
4c49HCYCorticosteroid-binding globulin/0.452
4cdmFO1Deoxyribodipyrimidine photolyase/0.452
5irnADPNucleotide binding oligomerization domain containing 2/0.452
4k5y1Q5Corticotropin-releasing factor receptor 1/0.452
1bwlFMNNADPH dehydrogenase 11.6.99.10.451
1dhiMTXDihydrofolate reductase1.5.1.30.451
1i24UPGUDP-sulfoquinovose synthase, chloroplastic3.13.1.10.451
1swpBTNStreptavidin/0.451
1x8b824Wee1-like protein kinase2.7.10.20.451
2jbsFMNp-hydroxyphenylacetate 3-hydroxylase, oxygenase component/0.451
2x9dITCTetracycline repressor protein class D/0.451
3c35KAIGlutamate receptor ionotropic, kainate 1/0.451
3d5qT30Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.451
3ssnMVIMycinamicin VI 2''-O-methyltransferase/0.451
3vt5YI2Vitamin D3 receptor/0.451
3w5p4OAVitamin D3 receptor/0.451
3zc3FADFerredoxin--NADP reductase1.18.1.20.451
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.451
4pb25UDNucleoside permease/0.451
4uwmFMN3,6-diketocamphane 1,6 monooxygenase1.14.130.451
1drfFOLDihydrofolate reductase1.5.1.30.450
1ia4TQ6Dihydrofolate reductase1.5.1.30.450
1qknRALEstrogen receptor beta/0.450
1ta6177Prothrombin3.4.21.50.450
1upcTPPN(2)-(2-carboxyethyl)arginine synthase/0.450
2a4nCOAAac(6')-Ii protein/0.450
2hc4VDXVitamin D3 receptor A/0.450
2v2zCDM4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.450
3ehjACPSensor histidine kinase DesK2.7.13.30.450
3gy9COAGCN5-related N-acetyltransferase/0.450
3pqbVGPPutative oxidoreductase/0.450
3sqzCOAPutative hydroxymethylglutaryl-CoA synthase/0.450
3uicNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.450
3w0hW12Vitamin D3 receptor/0.450
3zoiM2WIsopenicillin N synthase1.21.3.10.450
4bb6HD1Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.450
4fhd0TTSpore photoproduct lyase/0.450
4g8bHL6Alpha/beta hydrolase fold protein/0.450
4iji99TGlutathione S-transferase-like protein YibF/0.450
4j3mAJ8Tankyrase-22.4.2.300.450
5kghACOPredicted acetyltransferase/0.450
1ao8MTXDihydrofolate reductase1.5.1.30.449
1mkdZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.449
1rd4L08Integrin alpha-L/0.449
1y5rC0RCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.449
2kceD16Thymidylate synthase/0.449
2xgs44PUncharacterized protein/0.449
3bgxTMPThymidylate synthase/0.449
3djlFADPutative acyl-CoA dehydrogenase AidB1.3.990.449
3gmd2M3Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.449
3w0iO11Vitamin D3 receptor/0.449
4bb3KKAIsopenicillin N synthase1.21.3.10.449
4cryACOPanD regulatory factor/0.449
4lb9EVPSerum albumin/0.449
4u8iFDAUDP-galactopyranose mutase/0.449
1ix1BB2Peptide deformylase/0.448
1o6rR19Squalene--hopene cyclase4.2.1.1290.448
1og5SWFCytochrome P450 2C9/0.448
1txiTX5Vitamin D3 receptor/0.448
1y60H4M5,6,7,8-tetrahydromethanopterin hydro-lyase4.2.1.1470.448
1zgaHMKIsoflavone 4'-O-methyltransferase/0.448
2o4jVD4Vitamin D3 receptor/0.448
3pe2E1BCasein kinase II subunit alpha2.7.11.10.448
3tm5SFGUncharacterized protein/0.448
3zeiAWHO-acetylserine sulfhydrylase/0.448
4g1y0VOVitamin D3 receptor A/0.448
4jx1CAMCamphor 5-monooxygenase1.14.15.10.448
4wudANPDNA gyrase subunit B/0.448
1jtuLYBThymidylate synthase/0.447
1lwiNAP3-alpha-hydroxysteroid dehydrogenase1.1.1.500.447
1s0zEB1Vitamin D3 receptor/0.447
2fj1CTCTetracycline repressor protein class D/0.447
3inxJZCHeat shock protein HSP 90-alpha/0.447
3u8hBHPPhospholipase A2, membrane associated/0.447
4c1fX8ZMetallo-beta-lactamase type 2/0.447
4hkfACOAlpha-tubulin N-acetyltransferase 1/0.447
4nieNBHNuclear receptor ROR-gamma/0.447
5kf9ACOPredicted acetyltransferase/0.447
1fp2HMOIsoflavone-7-O-methyltransferase 82.1.1.1500.446
1m79MQ1Dihydrofolate reductase1.5.1.30.446
1pq6965Oxysterols receptor LXR-beta/0.446
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
2w3mFOLDihydrofolate reductase1.5.1.30.446
2wueKEK4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase3.7.1.170.446
2z4sADPChromosomal replication initiator protein DnaA/0.446
3bejMUFBile acid receptor/0.446
3bhlTHGThymidylate synthase/0.446
3l0lHC3Nuclear receptor ROR-gamma/0.446
3otqMZLBifunctional epoxide hydrolase 23.3.2.100.446
3vtdTKDVitamin D3 receptor/0.446
4bftZVTPantothenate kinase2.7.1.330.446
4bkqNAIEnoyl-[acyl-carrier-protein] reductase [NADH]/0.446
4dgo0JWCasein kinase II subunit alpha2.7.11.10.446
1bn1AL5Carbonic anhydrase 24.2.1.10.445
1cf3FADGlucose oxidase1.1.3.40.445
1f17NAIHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.445
1fvpFMANon-fluorescent flavoprotein/0.445
1fwmCB3Thymidylate synthase/0.445
1j8uH4BPhenylalanine-4-hydroxylase1.14.16.10.445
1r8qAFBCytohesin-2/0.445
1r8qAFBADP-ribosylation factor 1/0.445
1ve3SAMUncharacterized protein/0.445
2ay95PVAromatic-amino-acid aminotransferase2.6.1.570.445
2q9fC3SCholesterol 24-hydroxylase/0.445
2yeiXQIHeat shock protein HSP 90-alpha/0.445
2ze2T27Gag-Pol polyprotein2.7.7.490.445
2zlaVDBVitamin D3 receptor/0.445
3a1l2CCCytochrome P450/0.445
3c14FOKAdenylate cyclase type 2/0.445
3c14FOKAdenylate cyclase type 5/0.445
3hazFADBifunctional protein PutA/0.445
3kjrNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.445
3ns2PYVAbscisic acid receptor PYL2/0.445
3oimVZ5Carbonic anhydrase 24.2.1.10.445
3ojiPYVAbscisic acid receptor PYL3/0.445
3q43D66M1 family aminopeptidase3.4.110.445
3s1dZIRCytokinin dehydrogenase 11.5.99.120.445
3w0jT08Vitamin D3 receptor/0.445
4a322CDGlycylpeptide N-tetradecanoyltransferase/0.445
4deg0JJHepatocyte growth factor receptor2.7.10.10.445
4f9fGDPPutative glycosyltransferase/0.445
4g210VPVitamin D3 receptor A/0.445
4ia1BIVVitamin D3 receptor A/0.445
4jhiEMUNodulin-13/0.445
4oztP1AEcdysone receptor, putative/0.445
1ci7CB3Thymidylate synthase2.1.1.450.444
1dfoFFOSerine hydroxymethyltransferase2.1.2.10.444
1ejiTHFSerine hydroxymethyltransferase, cytosolic/0.444
1fdsESTEstradiol 17-beta-dehydrogenase 11.1.1.620.444
1fduESTEstradiol 17-beta-dehydrogenase 11.1.1.620.444
1tbbROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.444
1vyrFMNPentaerythritol tetranitrate reductase/0.444
2a1hGBNBranched-chain-amino-acid aminotransferase, mitochondrial2.6.1.420.444
2g97DGBNicotinamide phosphoribosyltransferase2.4.2.120.444
2getCOKPantothenate kinase2.7.1.330.444
3oafOAGDihydrofolate reductase1.5.1.30.444
3oewNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.444
3ozd4CTS-methyl-5'-thioadenosine phosphorylase/0.444
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.444
3tk3CPZCytochrome P450 2B41.14.14.10.444
3w6hAZMCarbonic anhydrase 14.2.1.10.444
4bcaFADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.444
4bchT7ZCyclin-dependent kinase 92.7.11.220.444
4cukNAID-lactate dehydrogenase/0.444
4htx19FcGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.444
4qa2SHHHistone deacetylase 83.5.1.980.444
4rrfA3SThreonine--tRNA ligase6.1.1.30.444
4uugPXGBranched-chain amino acid aminotransferase, putative/0.444
4uyf73BBromodomain-containing protein 2/0.444
4wh3ATPN-acetylhexosamine 1-kinase2.7.1.1620.444
4zjuNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.444
1eioGCHGastrotropin/0.443
1hfrMOTDihydrofolate reductase1.5.1.30.443
1rkhVD2Vitamin D3 receptor/0.443
1u0hFOKAdenylate cyclase type 2/0.443
1u0hFOKAdenylate cyclase type 5/0.443
1wp4NDP3-hydroxyisobutyrate dehydrogenase/0.443
1yhoTRRDihydrofolate reductase1.5.1.30.443
2hasC3OVitamin D3 receptor/0.443
2pl0STITyrosine-protein kinase Lck2.7.10.20.443
2r0pK2CPutative FAD-monooxygenase/0.443
2rhtC1E2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase3.7.1.80.443
2xlsFADPutative flavin-containing monooxygenase/0.443
2xviFADPutative flavin-containing monooxygenase/0.443
2yltFADPhenylacetone monooxygenase1.14.13.920.443
3bhrTHGThymidylate synthase/0.443
3bw4FMNPutative 2-nitropropane dioxygenase/0.443
3e6oA55Nitric oxide synthase, inducible1.14.13.390.443
3fp0FP015-O-acetyltransferase/0.443
3g493G4Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.443
3owuEQUSteroid Delta-isomerase5.3.3.10.443
3p62FMNPentaerythritol tetranitrate reductase/0.443
3rudNADUDP-N-acetylglucosamine 4-epimerase/0.443
4ag9COAGlucosamine 6-phosphate N-acetyltransferase/0.443
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
4b12C23Glycylpeptide N-tetradecanoyltransferase/0.443
4cvmANPUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase/0.443
4i9i1DYTankyrase-12.4.2.300.443
4imfSI3N-acetylneuraminate lyase/0.443
4nbjD3YD-tyrosyl-tRNA(Tyr) deacylase/0.443
4rquNADAlcohol dehydrogenase class-P/0.443
1ikxPNUGag-Pol polyprotein2.7.7.490.442
1jnzFADAdenylylsulfate reductase, subunit A (AprA)/0.442
1jolFFODihydrofolate reductase1.5.1.30.442
1n4hREANuclear receptor ROR-beta/0.442
1s3uTQDDihydrofolate reductase1.5.1.30.442
1sd2MTHS-methyl-5'-thioadenosine phosphorylase/0.442
1xp8AGSProtein RecA/0.442
2h55DZ8Heat shock protein HSP 90-alpha/0.442
2lbaCHOFatty acid binding protein 6/0.442
2pnjCHDFerrochelatase, mitochondrial4.99.1.10.442
2rl2UD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.442
3ansS38Bifunctional epoxide hydrolase 23.3.2.100.442
3d7zGK5Mitogen-activated protein kinase 14/0.442
3eheNADUDP-glucose 4-epimerase (GalE-1)/0.442
3gkjHC3Niemann-Pick C1 protein/0.442
3lkhLT6Genome polyprotein2.7.7.480.442
3n87N873-dehydroquinate dehydratase4.2.1.100.442
3ohh3HHBeta-secretase 13.4.23.460.442
3phiNDPShikimate dehydrogenase (NADP(+))/0.442
3w5rLOAVitamin D3 receptor/0.442
4fhf0TTSpore photoproduct lyase/0.442
4gki0JNAminoglycoside 3'-phosphotransferase AphA1-IAB/0.442
4gllNADUDP-glucuronic acid decarboxylase 14.1.1.350.442
4gz612VUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.442
4heu15JcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.442
4qemHC4Phospholipase A2 VRV-PL-VIIIa/0.442
4xcvNDPProbable hydroxyacid dehydrogenase protein/0.442
1enyNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.441
1fdwESTEstradiol 17-beta-dehydrogenase 11.1.1.620.441
1gky5GPGuanylate kinase2.7.4.80.441
1j3kWRABifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.441
1lkeDOGBilin-binding protein/0.441
1n0uSO1Elongation factor 2/0.441
1yinCM3Estrogen receptor/0.441
2g86UMPThymidylate synthase/0.441
2g8yNADHydroxycarboxylate dehydrogenase B/0.441
2gvcFADThiol-specific monooxygenase1.14.130.441
2hb7O1CVitamin D3 receptor/0.441
2jh0701Prothrombin3.4.21.50.441
2nv6ZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.441
2o1sTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.441
2pksG44Prothrombin3.4.21.50.441
3el8PD5Proto-oncogene tyrosine-protein kinase Src2.7.10.20.441
3g5mFADRibosyldihydronicotinamide dehydrogenase [quinone]/0.441
3pl8FADPyranose 2-oxidase/0.441
3qwbNDPProbable quinone oxidoreductase1.6.5.50.441
3sp9IL2Peroxisome proliferator-activated receptor delta/0.441
4gg1TZDBenzoylformate decarboxylase4.1.1.70.441
4h6pFMNChromate reductase/0.441
4h6uACOAlpha-tubulin N-acetyltransferase 1/0.441
4iteTEYVitamin D3 receptor/0.441
4jr51LSNicotinamide phosphoribosyltransferase2.4.2.120.441
4klnAGSTransitional endoplasmic reticulum ATPase3.6.4.60.441
4llkMEWcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.441
4psbGA3Cytokinin-specific binding protein/0.441
4rraA3TProbable threonine--tRNA ligase 26.1.1.30.441
4ruoBIVVitamin D3 receptor A/0.441
4tleAGSCircadian clock protein kinase KaiC2.7.11.10.441
4u0oMTALipoyl synthase 2/0.441
1ef92CPMethylmalonyl-CoA decarboxylase4.1.1.410.440
1kziTHGThymidylate synthase/0.440
1o5rFR9Adenosine deaminase3.5.4.40.440
1rx7FOLDihydrofolate reductase1.5.1.30.440
1ycfFMNNitric oxide reductase10.440
1z7yAA5Cysteine synthase 12.5.1.470.440
2chw039Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
2tohHBITyrosine 3-monooxygenase1.14.16.20.440
2tpsTPSThiamine-phosphate synthase/0.440
2vrbNAPTriphenylmethane reductase/0.440
3bk2U5PRibonuclease J/0.440
3c15FOKAdenylate cyclase type 2/0.440
3c15FOKAdenylate cyclase type 5/0.440
3d80Q22Dihydrofolate reductase1.5.1.30.440
3el7PD3Proto-oncogene tyrosine-protein kinase Src2.7.10.20.440
3g45988cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.440
3g5sFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.440
3jwcEKBDihydrofolate reductase/0.440
3jzfJZKBiotin carboxylase6.3.4.140.440
3p3zP3ZPutative cytochrome P450/0.440
3thrC2FGlycine N-methyltransferase2.1.1.200.440
3uzwNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.440
3vhhVHHAvidin/0.440
3wqmB29Diterpene synthase3.1.7.80.440
4a81DXCMajor pollen allergen Bet v 1-A/0.440
4awp99AHeat shock protein HSP 90-alpha/0.440
4cavMYAGlycylpeptide N-tetradecanoyltransferase2.3.1.970.440
4eiyZMAAdenosine receptor A2a/0.440
4fjz4FJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
4g6hNAIRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.440
4gbeSAHDNA adenine methylase2.1.1.720.440
4gevCB3Thymidylate synthase/0.440
4jqeANPCasein kinase II subunit alpha2.7.11.10.440
4ntcFADThioredoxin reductase gliT/0.440
4tjy3GNTankyrase-22.4.2.300.440
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.440
4wzyATPMaltokinase2.7.1.1750.440
4zasTYDCalS13/0.440
5dozNDPJamJ/0.440
5dp2NAPCurF/0.440
5iubCLRAdenosine receptor A2a/0.440
5kf1ACOPredicted acetyltransferase/0.440