Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2p6k | SAH | Diphthine synthase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2p6k | SAH | Diphthine synthase | / | 1.000 | |
| 2ed5 | SAH | Diphthine synthase | / | 0.858 | |
| 2dxw | SAH | Diphthine synthase | / | 0.849 | |
| 2ejk | SAH | Diphthine synthase | / | 0.841 | |
| 2p5c | SAH | Diphthine synthase | / | 0.824 | |
| 2dv7 | SAH | Diphthine synthase | / | 0.820 | |
| 2dsi | SAH | Diphthine synthase | / | 0.809 | |
| 2dxv | SAH | Diphthine synthase | / | 0.804 | |
| 2egs | SAH | Diphthine synthase | / | 0.801 | |
| 2el0 | SAH | Diphthine synthase | / | 0.795 | |
| 2eni | SAH | Diphthine synthase | / | 0.792 | |
| 2p5f | SAH | Diphthine synthase | / | 0.787 | |
| 2emr | SAH | Diphthine synthase | / | 0.784 | |
| 2p2x | SAH | Diphthine synthase | / | 0.784 | |
| 2dv4 | SAH | Diphthine synthase | / | 0.777 | |
| 2dsg | SAH | Diphthine synthase | / | 0.774 | |
| 2e8s | SAH | Diphthine synthase | / | 0.770 | |
| 2p6d | SAH | Diphthine synthase | / | 0.765 | |
| 2pcm | SAH | Diphthine synthase | / | 0.751 | |
| 2pb4 | SAH | Diphthine synthase | / | 0.748 | |
| 2ehl | SAH | Diphthine synthase | / | 0.744 | |
| 2emu | SAH | Diphthine synthase | / | 0.739 | |
| 2dv5 | SAH | Diphthine synthase | / | 0.738 | |
| 2eh5 | SAH | Diphthine synthase | / | 0.737 | |
| 2e7r | SAH | Diphthine synthase | / | 0.732 | |
| 2eka | SAH | Diphthine synthase | / | 0.728 | |
| 2ek7 | SAH | Diphthine synthase | / | 0.719 | |
| 2egb | SAH | Diphthine synthase | / | 0.716 | |
| 2egl | SAH | Diphthine synthase | / | 0.716 | |
| 1wng | SAH | Diphthine synthase | / | 0.715 | |
| 2owk | SAH | Diphthine synthase | / | 0.711 | |
| 2pb5 | SAH | Diphthine synthase | / | 0.709 | |
| 2dxx | SAH | Diphthine synthase | / | 0.707 | |
| 2e8q | SAH | Diphthine synthase | / | 0.703 | |
| 2p6i | SAH | Diphthine synthase | / | 0.698 | |
| 2hut | SAH | Diphthine synthase | / | 0.697 | |
| 2eeq | SAH | Diphthine synthase | / | 0.694 | |
| 2owg | SAH | Diphthine synthase | / | 0.694 | |
| 2owu | SAH | Diphthine synthase | / | 0.690 | |
| 2pck | SAH | Diphthine synthase | / | 0.688 | |
| 2en5 | SAH | Diphthine synthase | / | 0.682 | |
| 2z6r | SAH | Diphthine synthase | / | 0.681 | |
| 2ele | SAH | Diphthine synthase | / | 0.677 | |
| 1vce | SAH | Diphthine synthase | / | 0.676 | |
| 2e16 | SAH | Diphthine synthase | / | 0.676 | |
| 2e08 | SAH | Diphthine synthase | / | 0.674 | |
| 2pcg | SAH | Diphthine synthase | / | 0.673 | |
| 2huv | SAH | Diphthine synthase | / | 0.665 | |
| 2e17 | SAH | Diphthine synthase | / | 0.664 | |
| 2pch | SAH | Diphthine synthase | / | 0.664 | |
| 2owv | SAH | Diphthine synthase | / | 0.661 | |
| 2eh2 | SAH | Diphthine synthase | / | 0.660 | |
| 2p9d | SAH | Diphthine synthase | / | 0.659 | |
| 2pca | SAH | Diphthine synthase | / | 0.658 | |
| 2e8h | SAH | Diphthine synthase | / | 0.649 | |
| 2ek3 | SAH | Diphthine synthase | / | 0.649 | |
| 2hux | SAH | Diphthine synthase | / | 0.649 | |
| 2hr8 | SAH | Diphthine synthase | / | 0.646 | |
| 2pb6 | SAH | Diphthine synthase | / | 0.641 | |
| 2e15 | SAH | Diphthine synthase | / | 0.638 | |
| 2eh4 | SAH | Diphthine synthase | / | 0.628 | |
| 2e8r | SAH | Diphthine synthase | / | 0.627 | |
| 2ejj | SAH | Diphthine synthase | / | 0.622 | |
| 2ek2 | SAH | Diphthine synthase | / | 0.622 | |
| 2dv3 | SAH | Diphthine synthase | / | 0.618 | |
| 2pci | SAH | Diphthine synthase | / | 0.616 | |
| 2e4n | SAH | Diphthine synthase | / | 0.615 | |
| 2e07 | SAH | Diphthine synthase | / | 0.610 | |
| 2dsh | SAH | Diphthine synthase | / | 0.592 | |
| 2ek4 | SAH | Diphthine synthase | / | 0.589 | |
| 2dek | SAH | Diphthine synthase | / | 0.586 | |
| 2ejz | SAH | Diphthine synthase | / | 0.577 | |
| 2huq | SAH | Diphthine synthase | / | 0.573 | |
| 2p6l | SAH | Diphthine synthase | / | 0.572 | |
| 2eld | SAH | Diphthine synthase | / | 0.570 | |
| 2owf | SAH | Diphthine synthase | / | 0.568 | |
| 2ed3 | SAH | Diphthine synthase | / | 0.567 | |
| 2el3 | SAH | Diphthine synthase | / | 0.554 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.526 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.509 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.506 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.495 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.495 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.493 | |
| 1g63 | FMN | Epidermin decarboxylase | 4.1.1 | 0.491 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.490 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.490 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.490 | |
| 1lbc | CYZ | Glutamate receptor 2 | / | 0.489 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.488 | |
| 2psw | COA | N-alpha-acetyltransferase 50 | / | 0.485 | |
| 2ifa | FMN | Uncharacterized protein | / | 0.483 | |
| 2y3s | TIR | TamL | / | 0.480 | |
| 3zh8 | C58 | Protein kinase C iota type | 2.7.11.13 | 0.480 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.480 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.479 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.478 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.478 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.477 | |
| 3lsh | FAD | Pyranose 2-oxidase | / | 0.477 | |
| 5jsc | FAD | Putative acyl-CoA dehydrogenase | / | 0.477 | |
| 1ps9 | MDE | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.476 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.476 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.476 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.476 | |
| 4ji9 | 1M3 | Tyrosine-protein kinase JAK2 | / | 0.476 | |
| 4h3j | 10W | Beta-secretase 1 | 3.4.23.46 | 0.475 | |
| 2clq | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.474 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.474 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.474 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.474 | |
| 2q4b | NAP | Uncharacterized protein At5g02240 | / | 0.473 | |
| 1f8f | NAD | Benzyl alcohol dehydrogenase | / | 0.472 | |
| 2vwq | NAP | Glucose 1-dehydrogenase | / | 0.472 | |
| 2xhd | 7T9 | Glutamate receptor 2 | / | 0.472 | |
| 3d4p | NAD | L-lactate dehydrogenase 1 | 1.1.1.27 | 0.472 | |
| 4asu | ADP | ATP synthase subunit alpha, mitochondrial | / | 0.472 | |
| 1bim | 0QB | Renin | 3.4.23.15 | 0.471 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.471 | |
| 2q5g | 1FA | Peroxisome proliferator-activated receptor delta | / | 0.471 | |
| 4hbg | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.471 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.470 | |
| 3ndc | SAH | Precorrin-4 C(11)-methyltransferase | 2.1.1.133 | 0.470 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.470 | |
| 1pdh | FAS | p-hydroxybenzoate hydroxylase | / | 0.469 | |
| 2qbu | SAH | Precorrin-2 methyltransferase | / | 0.469 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.469 | |
| 3owa | FAD | Acyl-CoA dehydrogenase | / | 0.469 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.469 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.468 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.468 | |
| 2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.468 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.468 | |
| 3lpj | Z75 | Beta-secretase 1 | 3.4.23.46 | 0.468 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.467 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.467 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.467 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.467 | |
| 5eai | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.467 | |
| 2pj4 | 414 | Carboxypeptidase B | / | 0.466 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.465 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.465 | |
| 3uoz | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.465 | |
| 3uyl | TYD | Probable NDP-rhamnosyltransferase | / | 0.465 | |
| 4djy | 0KR | Beta-secretase 1 | 3.4.23.46 | 0.465 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.465 | |
| 4ejm | NAP | Putative zinc-binding dehydrogenase | / | 0.465 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.464 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.464 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.464 | |
| 2pnj | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.463 | |
| 3te5 | NAI | 5'-AMP-activated protein kinase subunit gamma | / | 0.463 | |
| 4eak | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.463 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.463 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.463 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.463 | |
| 4wri | OKA | Okadaic acid binding protein 2-alpha | / | 0.463 | |
| 2qs3 | UBE | Glutamate receptor ionotropic, kainate 1 | / | 0.462 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.462 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.461 | |
| 1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.461 | |
| 3ieu | GDP | GTPase Era | / | 0.461 | |
| 4i6a | HMG | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.88 | 0.461 | |
| 4irn | FAD | AnaB | / | 0.461 | |
| 1f20 | FAD | Nitric oxide synthase, brain | 1.14.13.39 | 0.460 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.460 | |
| 2ojt | UBA | Glutamate receptor ionotropic, kainate 1 | / | 0.460 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.460 | |
| 3p2e | SAH | 16S rRNA (adenine(1408)-N(1))-methyltransferase | 2.1.1.180 | 0.460 | |
| 4xgu | ADP | Putative pachytene checkpoint protein 2 | / | 0.460 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.459 | |
| 1npv | L27 | Gag-Pol polyprotein | 3.4.23.16 | 0.459 | |
| 1nuu | NAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.459 | |
| 1phg | MYT | Camphor 5-monooxygenase | 1.14.15.1 | 0.459 | |
| 2gna | GDU | UDP-N-acetylglucosamine 4,6-dehydratase (inverting) | 4.2.1.115 | 0.459 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.459 | |
| 2vo7 | M05 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.459 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.459 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.459 | |
| 3orf | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.459 | |
| 3ruc | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.459 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.459 | |
| 4f4d | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.459 | |
| 1dir | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.458 | |
| 1lsj | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.458 | |
| 1yqz | COA | Coenzyme A disulfide reductase | / | 0.458 | |
| 2hyd | ADP | Putative multidrug export ATP-binding/permease protein SAV1866 | 3.6.3 | 0.458 | |
| 2y1t | DUD | SPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS | 3.6.1.23 | 0.458 | |
| 3b70 | NAP | Enoyl reductase LovC | 1 | 0.458 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.458 | |
| 3lu1 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.458 | |
| 3vdq | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.458 | |
| 3vqs | JT1 | Genome polyprotein | / | 0.458 | |
| 3zuy | TCH | Transporter | / | 0.458 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.458 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.458 | |
| 5hws | NAP | 2-dehydropantoate 2-reductase | / | 0.458 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.457 | |
| 2a5k | AZP | Replicase polyprotein 1ab | 3.4.22 | 0.457 | |
| 2ahr | NAP | Pyrroline-5-carboxylate reductase | / | 0.457 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.457 | |
| 4i1i | NAD | Malate dehydrogenase | / | 0.457 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.456 | |
| 1nzf | UPG | DNA beta-glucosyltransferase | / | 0.456 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.456 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.456 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.456 | |
| 3lzs | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.456 | |
| 3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.456 | |
| 1ep1 | FMN | Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit | 1.3.1.14 | 0.455 | |
| 1f8w | FAD | NADH peroxidase | 1.11.1.1 | 0.455 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.455 | |
| 2cft | PLP | Pyridoxal phosphate phosphatase | / | 0.455 | |
| 3u9e | COA | Lmo1369 protein | / | 0.455 | |
| 5eb5 | FAD | (R)-mandelonitrile lyase 1 | 4.1.2.10 | 0.455 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.454 | |
| 1tqf | 32P | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 2ien | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.454 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.454 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 3slk | NDP | Polyketide synthase extender module 2 | / | 0.454 | |
| 4cvm | ANP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.454 | |
| 1dxo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.453 | |
| 1hbv | GAN | Gag-Pol polyprotein | / | 0.453 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 1omo | NAD | Alanine dehydrogenase | / | 0.453 | |
| 1psa | 0ZL | Pepsin A | 3.4.23.1 | 0.453 | |
| 2b53 | D23 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.453 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 2gmh | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.453 | |
| 3ig6 | 438 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.453 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.453 | |
| 3mpj | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.453 | |
| 3ox4 | NAD | Alcohol dehydrogenase 2 | 1.1.1.1 | 0.453 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.453 | |
| 1bdl | IM1 | Gag-Pol polyprotein | 3.4.23.16 | 0.452 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.452 | |
| 1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.452 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.452 | |
| 1yqd | NAP | Sinapyl alcohol dehydrogenase | / | 0.452 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.452 | |
| 2p83 | MR0 | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 2r7b | 253 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.452 | |
| 3ilt | TRU | Glutamate receptor 2 | / | 0.452 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.452 | |
| 4u0m | GTP | Cyclic GMP-AMP synthase | / | 0.452 | |
| 4wud | ANP | DNA gyrase subunit B | / | 0.452 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.451 | |
| 1msm | JE2 | Gag-Pol polyprotein | 3.4.23.16 | 0.451 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 2ekl | NAD | D-3-phosphoglycerate dehydrogenase | / | 0.451 | |
| 2fzw | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.451 | |
| 2q1w | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.451 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.451 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 4bc7 | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.451 | |
| 4dfg | 0JV | Gag-Pol polyprotein | 3.4.23.16 | 0.451 | |
| 5doz | NDP | JamJ | / | 0.451 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 1juv | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.450 | |
| 2znp | K55 | Peroxisome proliferator-activated receptor delta | / | 0.450 | |
| 3a3g | DLZ | Lumazine protein | / | 0.450 | |
| 3ehe | NAD | UDP-glucose 4-epimerase (GalE-1) | / | 0.450 | |
| 3r9u | FAD | Thioredoxin reductase | / | 0.450 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.450 | |
| 4f5y | C2E | Stimulator of interferon genes protein | / | 0.450 | |
| 4frk | DWD | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 4h3f | 10O | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.450 | |
| 4nd3 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.450 | |
| 4xuh | SFI | Peroxisome proliferator-activated receptor gamma | / | 0.450 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.449 | |
| 1kp3 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.449 | |
| 1udb | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.449 | |
| 1udy | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.449 | |
| 1x1a | SAM | C-20 methyltransferase | / | 0.449 | |
| 2a92 | NAI | L-lactate dehydrogenase | / | 0.449 | |
| 2dft | ADP | Shikimate kinase | 2.7.1.71 | 0.449 | |
| 2fn7 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.449 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.449 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.449 | |
| 3c21 | 2BA | DNA integrity scanning protein DisA | / | 0.449 | |
| 3to6 | LYS_CMC | Histone acetyltransferase ESA1 | / | 0.449 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.449 | |
| 4ef8 | FMN | Dihydroorotate dehydrogenase (fumarate) | / | 0.449 | |
| 4ge7 | 0K5 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.449 | |
| 4nd4 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.449 | |
| 4yao | FMN | NADPH--cytochrome P450 reductase | / | 0.449 | |
| 1ep3 | FMN | Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit | 1.3.1.14 | 0.448 | |
| 1mja | COA | Histone acetyltransferase ESA1 | / | 0.448 | |
| 2cmj | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.448 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.448 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 3c1y | 2BA | DNA integrity scanning protein DisA | / | 0.448 | |
| 3rsv | 3RS | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 3ruf | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.448 | |
| 3uoy | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.448 | |
| 1cbf | SAH | Cobalt-precorrin-4 C(11)-methyltransferase | 2.1.1.271 | 0.447 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.447 | |
| 1hdr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.447 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1qr6 | NAD | NAD-dependent malic enzyme, mitochondrial | 1.1.1.38 | 0.447 | |
| 2ag5 | NAD | 3-hydroxybutyrate dehydrogenase type 2 | / | 0.447 | |
| 2c20 | NAD | UDP-glucose 4-epimerase | / | 0.447 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.447 | |
| 2ivn | ANP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.447 | |
| 2ou2 | ACO | Histone acetyltransferase KAT5 | / | 0.447 | |
| 2z7h | GG3 | Geranylgeranyl pyrophosphate synthase | / | 0.447 | |
| 3pb3 | SAH | 16S rRNA (adenine(1408)-N(1))-methyltransferase | 2.1.1.180 | 0.447 | |
| 3r7k | FDA | Probable acyl CoA dehydrogenase | / | 0.447 | |
| 3w8e | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.447 | |
| 4dpf | 0LG | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 4dpy | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.447 | |
| 4i8z | G08 | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 4uwm | FMN | 3,6-diketocamphane 1,6 monooxygenase | 1.14.13 | 0.447 | |
| 1ege | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.446 | |
| 1h8h | ATP | ATP synthase subunit alpha, mitochondrial | / | 0.446 | |
| 1h8h | ATP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.446 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.446 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.446 | |
| 2zts | ADP | Uncharacterized protein | / | 0.446 | |
| 3ik6 | HCZ | Glutamate receptor 2 | / | 0.446 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.446 | |
| 4zju | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.446 | |
| 5fs7 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.446 | |
| 1ay0 | TPP | Transketolase 1 | 2.2.1.1 | 0.445 | |
| 1ydt | IQB | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.445 | |
| 2z54 | AB1 | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 3d91 | REM | Renin | 3.4.23.15 | 0.445 | |
| 3qls | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 3tne | RIT | Candidapepsin-1 | 3.4.23.24 | 0.445 | |
| 3upk | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.445 | |
| 4eag | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.445 | |
| 4g74 | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.445 | |
| 4pl0 | ANP | Microcin-J25 export ATP-binding/permease protein McjD | / | 0.445 | |
| 4q72 | FAD | Bifunctional protein PutA | / | 0.445 | |
| 4qec | NAP | ElxO | / | 0.445 | |
| 4xum | IMN | Peroxisome proliferator-activated receptor gamma | / | 0.445 | |
| 5a88 | ADP | Riboflavin biosynthesis protein RibF | 2.7.1.26 | 0.445 | |
| 5dp2 | NAP | CurF | / | 0.445 | |
| 1dhr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.444 | |
| 1egd | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.444 | |
| 1n2s | NAI | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.444 | |
| 1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.444 | |
| 1yb5 | NAP | Quinone oxidoreductase | 1.6.5.5 | 0.444 | |
| 2ath | 3EA | Peroxisome proliferator-activated receptor gamma | / | 0.444 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.444 | |
| 2c12 | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.444 | |
| 2hk9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.444 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.444 | |
| 3djj | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.444 | |
| 3suf | SUE | Polyprotein | / | 0.444 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.444 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.444 | |
| 4b78 | KGG | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 4egb | NAD | dTDP-glucose 4,6-dehydratase | / | 0.444 | |
| 4fj1 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.444 | |
| 4loi | 1YC | Stimulator of interferon genes protein | / | 0.444 | |
| 1ja0 | FMN | NADPH--cytochrome P450 reductase | / | 0.443 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.443 | |
| 1u3c | FAD | Cryptochrome-1 | / | 0.443 | |
| 1vik | BAY | Gag-Pol polyprotein | / | 0.443 | |
| 1xl8 | 152 | Peroxisomal carnitine O-octanoyltransferase | 2.3.1.137 | 0.443 | |
| 2acx | ANP | G protein-coupled receptor kinase 6 | 2.7.11.16 | 0.443 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.443 | |
| 2fgj | ATP | Alpha-hemolysin translocation ATP-binding protein HlyB | / | 0.443 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.443 | |
| 2g1y | 5IG | Renin | 3.4.23.15 | 0.443 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.443 | |
| 2gz7 | D3F | Orf1a polyprotein | / | 0.443 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.443 | |
| 2xx9 | 1NF | Glutamate receptor 2 | / | 0.443 | |
| 2ylz | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.443 | |
| 3lpi | Z74 | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 3up5 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.443 | |
| 4acx | S8Z | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 5dw6 | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.443 | |
| 1a72 | PAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.442 | |
| 1h5q | NAP | NADP-dependent mannitol dehydrogenase | 1.1.1.138 | 0.442 | |
| 1i7g | AZ2 | Peroxisome proliferator-activated receptor alpha | / | 0.442 | |
| 1nhh | ANP | DNA mismatch repair protein MutL | / | 0.442 | |
| 1y7l | ASN_LEU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.442 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.442 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.442 | |
| 2hrc | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.442 | |
| 3a1n | NAD | NDP-sugar epimerase | / | 0.442 | |
| 3ad9 | NAD | Subunit alpha of sarocosine oxidase | / | 0.442 | |
| 3ggf | GVD | Serine/threonine-protein kinase 26 | / | 0.442 | |
| 3nut | SAH | Precorrin-3 methylase | / | 0.442 | |
| 4a84 | DXC | Major pollen allergen Bet v 1-A | / | 0.442 | |
| 4m87 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.442 | |
| 4nd2 | A3D | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.442 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.442 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.442 | |
| 4r21 | STR | Cytochrome P450 family 17 polypeptide 2 | / | 0.442 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.442 | |
| 1e1q | ANP | ATP synthase subunit alpha, mitochondrial | / | 0.441 | |
| 1e1q | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.441 | |
| 1hyg | NAP | L-2-hydroxycarboxylate dehydrogenase (NAD(P)(+)) | / | 0.441 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.441 | |
| 1q8w | M77 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.441 | |
| 1u8v | FAD | 4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase | / | 0.441 | |
| 2fgk | ATP | Alpha-hemolysin translocation ATP-binding protein HlyB | / | 0.441 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.441 | |
| 2ieb | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 2rhg | IGP | Tryptophan synthase alpha chain | / | 0.441 | |
| 2y0m | ACO | Histone acetyltransferase KAT8 | / | 0.441 | |
| 2y4g | TIR | TamL | / | 0.441 | |
| 2zb3 | NDP | Prostaglandin reductase 2 | 1.3.1.48 | 0.441 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.441 | |
| 3cic | 316 | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 3ijo | B4D | Glutamate receptor 2 | / | 0.441 | |
| 3iqh | TYR_ASP_ILE | Cysteine synthase | 2.5.1.47 | 0.441 | |
| 3pvc | FAD | tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC | / | 0.441 | |
| 3vye | VYE | Renin | 3.4.23.15 | 0.441 | |
| 4n5n | NAP | Acetoacetyl-CoA reductase | 1.1.1.36 | 0.441 | |
| 4xgx | ADP | FAD:protein FMN transferase | / | 0.441 | |
| 1fvp | FMA | Non-fluorescent flavoprotein | / | 0.440 | |
| 1gpd | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.440 | |
| 1k6p | XN3 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 1llq | NAD | NAD-dependent malic enzyme, mitochondrial | 1.1.1.38 | 0.440 | |
| 1pmn | 984 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.440 | |
| 1q0r | AKT | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.440 | |
| 1qor | NDP | Quinone oxidoreductase 1 | / | 0.440 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.440 | |
| 1vbi | NAD | Malate/L-lactate dehydrogenase family protein | / | 0.440 | |
| 2f4b | EHA | Peroxisome proliferator-activated receptor gamma | / | 0.440 | |
| 2igo | FAD | Pyranose 2-oxidase | / | 0.440 | |
| 2rcy | NAP | Pyrroline-5-carboxylate reductase | / | 0.440 | |
| 2uuv | FAD | Alkyldihydroxyacetonephosphate synthase | 2.5.1.26 | 0.440 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 2vhz | NAI | Alanine dehydrogenase | 1.4.1.1 | 0.440 | |
| 3csc | ACO | Citrate synthase, mitochondrial | 2.3.3.1 | 0.440 | |
| 3own | 3OW | Renin | 3.4.23.15 | 0.440 | |
| 3qi4 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 3r2b | 05B | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.440 | |
| 3u33 | FAD | Putative acyl-CoA dehydrogenase AidB | 1.3.99 | 0.440 | |
| 4c0b | ATP | mRNA cleavage and polyadenylation factor CLP1 | / | 0.440 | |
| 4eb7 | PLP | Cysteine desulfurase IscS 2 | / | 0.440 | |
| 4ebf | NAD | Phosphonate dehydrogenase | 1.20.1.1 | 0.440 | |
| 4gl4 | NAI | Alcohol dehydrogenase class-3 | / | 0.440 | |
| 4h3g | 10Q | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 4ig0 | 1FG | Gag-Pol polyprotein | 2.7.7.49 | 0.440 | |
| 4oxy | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.440 |