sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3cox | FAD | Cholesterol oxidase | 1.1.3.6 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 3cox | FAD | Cholesterol oxidase | 1.1.3.6 | 1.411 | |
| 4u2t | FAD | Cholesterol oxidase | 1.1.3.6 | 1.283 | |
| 1b8s | FAD | Cholesterol oxidase | 1.1.3.6 | 1.279 | |
| 2gew | FAD | Cholesterol oxidase | 1.1.3.6 | 1.279 | |
| 3gyi | FAD | Cholesterol oxidase | 1.1.3.6 | 1.278 | |
| 1cbo | FAD | Cholesterol oxidase | 1.1.3.6 | 1.269 | |
| 4u2s | FDA | Cholesterol oxidase | 1.1.3.6 | 1.264 | |
| 1n4v | FAD | Cholesterol oxidase | 1.1.3.6 | 1.263 | |
| 1ijh | FAD | Cholesterol oxidase | 1.1.3.6 | 1.262 | |
| 1n4u | FAE | Cholesterol oxidase | 1.1.3.6 | 1.260 | |
| 3gyj | FAD | Cholesterol oxidase | 1.1.3.6 | 1.260 | |
| 4rek | FAD | Cholesterol oxidase | 1.1.3.6 | 1.260 | |
| 4xwr | FAD | Cholesterol oxidase | 1.1.3.6 | 1.260 | |
| 3cnj | FAD | Cholesterol oxidase | 1.1.3.6 | 1.259 | |
| 1b4v | FAD | Cholesterol oxidase | 1.1.3.6 | 1.252 | |
| 3b6d | FAE | Cholesterol oxidase | 1.1.3.6 | 1.250 | |
| 1mxt | FAE | Cholesterol oxidase | 1.1.3.6 | 1.246 | |
| 1n1p | FAD | Cholesterol oxidase | 1.1.3.6 | 1.245 | |
| 1n4w | FAD | Cholesterol oxidase | 1.1.3.6 | 1.245 | |
| 4xxg | FAD | Cholesterol oxidase | 1.1.3.6 | 1.245 | |
| 4u2l | SFD | Cholesterol oxidase | 1.1.3.6 | 1.198 | |
| 1cc2 | FAD | Cholesterol oxidase | 1.1.3.6 | 1.176 | |
| 4qi5 | FAD | Cellobiose dehydrogenase | / | 0.951 | |
| 1gpe | FAD | Glucose oxidase | 1.1.3.4 | 0.930 | |
| 3qvr | FAD | Glucose oxidase | 1.1.3.4 | 0.925 | |
| 3qvp | FAD | Glucose oxidase | 1.1.3.4 | 0.912 | |
| 3t37 | FAD | Pyridoxine 4-oxidase | / | 0.902 | |
| 1ju2 | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.897 | |
| 4qi4 | FAD | Cellobiose dehydrogenase | / | 0.896 | |
| 5eb5 | FAD | (R)-mandelonitrile lyase 1 | 4.1.2.10 | 0.882 | |
| 4ynt | FDA | Glucose oxidase, putative | / | 0.874 | |
| 4udq | FAD | 5-(hydroxymethyl)furfural oxidase | / | 0.870 | |
| 3gdp | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.864 | |
| 1gal | FAD | Glucose oxidase | 1.1.3.4 | 0.853 | |
| 4udr | FAD | 5-(hydroxymethyl)furfural oxidase | / | 0.848 | |
| 1cf3 | FAD | Glucose oxidase | 1.1.3.4 | 0.840 | |
| 2tpr | FAD | Trypanothione reductase | 1.8.1.12 | 0.838 | |
| 4nev | FAD | Trypanothione reductase | / | 0.831 | |
| 2wba | FAD | Trypanothione reductase | 1.8.1.12 | 0.821 | |
| 3pl8 | FAD | Pyranose 2-oxidase | / | 0.815 | |
| 4qi7 | FAD | Cellobiose dehydrogenase | / | 0.810 | |
| 3ict | FAD | Coenzyme A disulfide reductase | / | 0.808 | |
| 3q9t | FAY | Uncharacterized protein | / | 0.808 | |
| 4fwe | FAD | Lysine-specific histone demethylase 1B | 1 | 0.808 | |
| 3ish | FAD | Thioredoxin reductase | 1.8.1.9 | 0.801 | |
| 1fec | FAD | Trypanothione reductase | 1.8.1.12 | 0.798 | |
| 2rab | FAD | Glutathione amide reductase | / | 0.795 | |
| 1feb | FAD | Trypanothione reductase | 1.8.1.12 | 0.794 | |
| 2q7v | FAD | Thioredoxin reductase | / | 0.794 | |
| 1h7w | FAD | Dihydropyrimidine dehydrogenase [NADP(+)] | 1.3.1.2 | 0.791 | |
| 1h81 | FAD | Polyamine oxidase | 1.5.3.14 | 0.791 | |
| 2yg4 | FAD | Putrescine oxidase | / | 0.787 | |
| 2i0z | FAD | NAD(FAD)-utilizing dehydrogenases | / | 0.786 | |
| 2wow | FAD | Trypanothione reductase | / | 0.783 | |
| 3v76 | FDA | Uncharacterized protein | / | 0.783 | |
| 4gcm | FAD | Thioredoxin reductase | 1.8.1.9 | 0.780 | |
| 2yg3 | FAD | Putrescine oxidase | / | 0.778 | |
| 3nlc | FAD | Uncharacterized protein | / | 0.777 | |
| 4opd | FDA | Conserved Archaeal protein | / | 0.777 | |
| 1gte | FAD | Dihydropyrimidine dehydrogenase [NADP(+)] | 1.3.1.2 | 0.776 | |
| 4fwf | FAD | Lysine-specific histone demethylase 1B | 1 | 0.770 | |
| 2yg7 | FAD | Putrescine oxidase | / | 0.768 | |
| 3rha | FDA | Putrescine oxidase | / | 0.767 | |
| 3ntd | FAD | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.766 | |
| 3oc4 | FAD | Oxidoreductase, pyridine nucleotide-disulfide family | / | 0.766 | |
| 1bwc | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.765 | |
| 1rp0 | AHZ | Thiamine thiazole synthase, chloroplastic | / | 0.763 | |
| 2zzc | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.763 | |
| 3k4c | FAD | Pyranose 2-oxidase | / | 0.763 | |
| 1tyt | FAD | Trypanothione reductase | 1.8.1.12 | 0.761 | |
| 4kpr | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.761 | |
| 1get | FAD | Glutathione reductase | 1.8.1.7 | 0.759 | |
| 4hsu | FAD | Lysine-specific histone demethylase 1B | 1 | 0.759 | |
| 4mih | FAD | Pyranose 2-oxidase | 1.1.3.10 | 0.759 | |
| 1geu | FAD | Glutathione reductase | 1.8.1.7 | 0.755 | |
| 2ign | FAD | Pyranose 2-oxidase | / | 0.755 | |
| 2gmh | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.754 | |
| 1bzl | FAD | Trypanothione reductase | 1.8.1.12 | 0.753 | |
| 2hqm | FAD | Glutathione reductase | 1.8.1.7 | 0.753 | |
| 4o5q | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.753 | |
| 3ean | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.752 | |
| 4z26 | FAD | Putative GMC-type oxidoreductase R135 | 1 | 0.752 | |
| 1gth | FAD | Dihydropyrimidine dehydrogenase [NADP(+)] | 1.3.1.2 | 0.751 | |
| 2igo | FAD | Pyranose 2-oxidase | / | 0.748 | |
| 3djg | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.748 | |
| 4eqw | FAD | Coenzyme A disulfide reductase | / | 0.748 | |
| 4opc | FDA | Conserved Archaeal protein | / | 0.748 | |
| 1fea | FAD | Trypanothione reductase | 1.8.1.12 | 0.747 | |
| 2zz0 | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.747 | |
| 4mok | FAD | Pyranose 2-oxidase | / | 0.747 | |
| 2eq6 | FAD | Dihydrolipoyl dehydrogenase | / | 0.746 | |
| 3fpz | AHZ | Thiamine thiazole synthase | / | 0.746 | |
| 4b63 | FAD | L-ornithine N(5)-monooxygenase | / | 0.746 | |
| 1grb | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.745 | |
| 1xpq | FAD | Polyamine oxidase FMS1 | / | 0.745 | |
| 2yg5 | FAD | Putrescine oxidase | / | 0.745 | |
| 3dgz | FAD | Thioredoxin reductase 2, mitochondrial | 1.8.1.9 | 0.745 | |
| 4ocg | FAD | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.744 | |
| 4opg | FDA | Conserved Archaeal protein | / | 0.743 | |
| 2dw4 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.741 | |
| 3djj | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.741 | |
| 3sqp | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.741 | |
| 1f8w | FAD | NADH peroxidase | 1.11.1.1 | 0.740 | |
| 2hko | FAD | Lysine-specific histone demethylase 1A | 1 | 0.740 | |
| 4bk3 | FAD | Probable salicylate monooxygenase | / | 0.740 | |
| 3lsi | FAD | Pyranose 2-oxidase | / | 0.739 | |
| 1gxf | FAD | Trypanothione reductase | 1.8.1.12 | 0.738 | |
| 2c7g | FAD | NADPH-ferredoxin reductase FprA | 1.18.1.2 | 0.738 | |
| 3k4n | FAD | Pyranose 2-oxidase | / | 0.738 | |
| 5buk | FAD | FADH2-dependent halogenase | / | 0.738 | |
| 3r9u | FAD | Thioredoxin reductase | / | 0.737 | |
| 2y48 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.736 | |
| 4gut | FAD | Lysine-specific histone demethylase 1B | 1 | 0.736 | |
| 1ger | FAD | Glutathione reductase | 1.8.1.7 | 0.735 | |
| 1gsn | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.734 | |
| 2a8x | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.733 | |
| 1ges | FAD | Glutathione reductase | 1.8.1.7 | 0.732 | |
| 2q0l | FAD | Thioredoxin reductase | 1.8.1.9 | 0.732 | |
| 4j57 | FAD | Thioredoxin reductase 2 | 1.8.1.9 | 0.732 | |
| 1e1m | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.731 | |
| 3grs | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.731 | |
| 3lsh | FAD | Pyranose 2-oxidase | / | 0.731 | |
| 3sm8 | FNK | FAD-dependent catabolic D-arginine dehydrogenase DauA | / | 0.731 | |
| 3uoz | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.731 | |
| 5j60 | FAD | Thioredoxin reductase | / | 0.731 | |
| 1zmc | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.730 | |
| 1lqu | FAD | NADPH-ferredoxin reductase FprA | 1.18.1.2 | 0.729 | |
| 3qfa | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.728 | |
| 3rnm | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.728 | |
| 4m52 | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.728 | |
| 5hsa | FAS | Alcohol oxidase 1 | 1.1.3.13 | 0.728 | |
| 1gre | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.727 | |
| 1tde | FAD | Thioredoxin reductase | 1.8.1.9 | 0.727 | |
| 1tdf | FAD | Thioredoxin reductase | 1.8.1.9 | 0.727 | |
| 1v0j | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.727 | |
| 2zbw | FAD | Ferredoxin--NADP reductase | / | 0.727 | |
| 3dk4 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.726 | |
| 3oz2 | FAD | Digeranylgeranylglycerophospholipid reductase | / | 0.725 | |
| 3uov | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.725 | |
| 4b64 | FAD | L-ornithine N(5)-monooxygenase | / | 0.725 | |
| 4b69 | FAD | L-ornithine N(5)-monooxygenase | / | 0.725 | |
| 2gh5 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.724 | |
| 3bi2 | FAD | Polyamine oxidase FMS1 | / | 0.723 | |
| 1yy5 | FAD | Polyamine oxidase FMS1 | / | 0.722 | |
| 1zmd | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.722 | |
| 2w0h | FAD | Trypanothione reductase | / | 0.722 | |
| 2yqu | FAD | Dihydrolipoyl dehydrogenase | / | 0.722 | |
| 5g3s | FDA | Flavin-dependent L-tryptophan oxidase VioA | / | 0.722 | |
| 1rsg | FAD | Polyamine oxidase FMS1 | / | 0.720 | |
| 3e4v | FMN | Uncharacterized protein | / | 0.720 | |
| 3lad | FAD | Dihydrolipoyl dehydrogenase | / | 0.720 | |
| 4mo2 | FAD | UDP-galactopyranose mutase | / | 0.720 | |
| 1h83 | FAD | Polyamine oxidase | 1.5.3.14 | 0.718 | |
| 1trb | FAD | Thioredoxin reductase | 1.8.1.9 | 0.718 | |
| 3nta | FAD | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.718 | |
| 2cvj | FAD | Thioredoxin reductase related protein | / | 0.717 | |
| 4em3 | FAD | Coenzyme A disulfide reductase | / | 0.717 | |
| 4opl | FDA | Conserved Archaeal protein | / | 0.717 | |
| 4opt | FDA | Conserved Archaeal protein | / | 0.717 | |
| 2yg6 | FAD | Putrescine oxidase | / | 0.716 | |
| 2gv8 | FAD | Thiol-specific monooxygenase | 1.14.13 | 0.715 | |
| 4o5u | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.715 | |
| 3cgc | FAD | Coenzyme A disulfide reductase | / | 0.714 | |
| 4fk1 | FAD | Putative thioredoxin reductase | / | 0.714 | |
| 1ng4 | FAD | Glycine oxidase | 1.4.3.19 | 0.713 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.713 | |
| 3ic9 | FAD | Putative dihydrolipoamide dehydrogenase | / | 0.713 | |
| 4jn9 | FAD | DepH | / | 0.713 | |
| 4mo2 | FDA | UDP-galactopyranose mutase | / | 0.713 | |
| 1e1n | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.711 | |
| 3lxd | FAD | FAD-dependent pyridine nucleotide-disulfide oxidoreductase | / | 0.711 | |
| 3nn6 | FB0 | 6-hydroxy-L-nicotine oxidase | / | 0.711 | |
| 4b68 | FAD | L-ornithine N(5)-monooxygenase | / | 0.711 | |
| 4nte | FAD | DepH | / | 0.711 | |
| 2q0k | FAD | Thioredoxin reductase | 1.8.1.9 | 0.710 | |
| 3bg7 | FAD | Pyranose 2-oxidase | / | 0.710 | |
| 4jq9 | FAD | Dihydrolipoyl dehydrogenase | / | 0.710 | |
| 4tlx | FDA | KtzI | / | 0.710 | |
| 4yxd | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.710 | |
| 1ng3 | FAD | Glycine oxidase | 1.4.3.19 | 0.709 | |
| 2c3c | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.709 | |
| 2x8g | FAD | Thioredoxin glutathione reductase | / | 0.709 | |
| 4tm1 | FDA | KtzI | / | 0.709 | |
| 4hb9 | FAD | Uncharacterized protein | / | 0.708 | |
| 1dnc | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.707 | |
| 3cge | FAD | Coenzyme A disulfide reductase | / | 0.707 | |
| 4tm4 | FDA | KtzI | / | 0.707 | |
| 1ebd | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.706 | |
| 2isl | FNR | 5,6-dimethylbenzimidazole synthase | 1.13.11.79 | 0.706 | |
| 3atr | FDA | Conserved Archaeal protein | / | 0.706 | |
| 4gus | FAD | Lysine-specific histone demethylase 1B | 1 | 0.706 | |
| 2dki | FAD | 3-hydroxybenzoate 4-monooxygenase | 1.14.13.23 | 0.705 | |
| 2r0c | FAD | Putative FAD-monooxygenase | / | 0.705 | |
| 3up4 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.705 | |
| 4fwj | FAD | Lysine-specific histone demethylase 1B | 1 | 0.705 | |
| 3qfb | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.704 | |
| 4d7e | FAD | Putative lysine-N-oxygenase | / | 0.704 | |
| 1ep3 | FAD | Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit | / | 0.703 | |
| 1h6v | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.703 | |
| 2jae | FAD | L-amino acid oxidase | / | 0.703 | |
| 1e6e | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.702 | |
| 2jb2 | FAD | L-amino acid oxidase | / | 0.702 | |
| 3atq | FDA | Conserved Archaeal protein | / | 0.702 | |
| 3cgb | FAD | Coenzyme A disulfide reductase | / | 0.702 | |
| 3klj | FAD | NADH-rubredoxin oxidoreductase | 1.18.1.1 | 0.702 | |
| 4ccq | FAD | Thioredoxin reductase | / | 0.702 | |
| 1zx9 | FAD | Mercuric reductase | 1.16.1.1 | 0.701 | |
| 2isk | FNR | 5,6-dimethylbenzimidazole synthase | 1.13.11.79 | 0.701 | |
| 4c3y | FAD | 3-ketosteroid dehydrogenase | / | 0.700 | |
| 5ez7 | FAD | Probable FAD-dependent oxidoreductase PA4991 | / | 0.700 | |
| 5g3t | FDA | Flavin-dependent L-tryptophan oxidase VioA | / | 0.700 | |
| 1c0k | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.699 | |
| 2jk6 | FAD | Trypanothione reductase | / | 0.699 | |
| 2vvl | FAD | Monoamine oxidase N | 1.4.3.4 | 0.699 | |
| 2x8h | FAD | Thioredoxin glutathione reductase | / | 0.699 | |
| 2jb1 | FAD | L-amino acid oxidase | / | 0.698 | |
| 4b67 | FAD | L-ornithine N(5)-monooxygenase | / | 0.698 | |
| 2bab | FAD | Putative aminooxidase | / | 0.697 | |
| 3k7m | FAD | 6-hydroxy-L-nicotine oxidase | / | 0.697 | |
| 4ykf | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.697 | |
| 4b66 | FAD | L-ornithine N(5)-monooxygenase | / | 0.696 | |
| 4gr1 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.696 | |
| 4yry | FAD | Glutamate synthase, beta subunit | / | 0.696 | |
| 5cku | FAD | L-ornithine N(5)-monooxygenase | / | 0.696 | |
| 2du8 | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.695 | |
| 2e1m | FAD | L-glutamate oxidase | / | 0.695 | |
| 4emj | FAD | Toluene 1,2-dioxygenase system ferredoxin--NAD(+) reductase component | 1.18.1.3 | 0.695 | |
| 4nzh | FAD | L-ornithine N(5)-monooxygenase | / | 0.695 | |
| 3urh | FAD | Dihydrolipoyl dehydrogenase | / | 0.694 | |
| 1xdi | FAD | NAD(P)H dehydrogenase (quinone) | / | 0.693 | |
| 1zy8 | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.693 | |
| 2nvk | FAD | Thioredoxin reductase 1, mitochondrial | 1.8.1.9 | 0.693 | |
| 3if9 | FAD | Glycine oxidase | 1.4.3.19 | 0.693 | |
| 4at0 | FAD | Possible succinate dehydrogenase | / | 0.693 | |
| 4ykg | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.693 | |
| 1gra | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.692 | |
| 4la1 | FAD | Thioredoxin glutathione reductase | / | 0.692 | |
| 1wam | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.691 | |
| 4h2p | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.691 | |
| 1vdc | FAD | Thioredoxin reductase 1, mitochondrial | 1.8.1.9 | 0.690 | |
| 2c3d | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.690 | |
| 2fje | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.690 | |
| 2gvc | FAD | Thiol-specific monooxygenase | 1.14.13 | 0.690 | |
| 2z6d | FMN | Phototropin-2 | 2.7.11.1 | 0.690 | |
| 3dme | FAD | Putative conserved exported protein | / | 0.690 | |
| 4k5r | FAD | Oxygenase | / | 0.690 | |
| 2eq9 | FAD | Dihydrolipoyl dehydrogenase | / | 0.689 | |
| 3f8d | FAD | NADH oxidase/thioredoxin reductase | / | 0.689 | |
| 5l3d | FAD | Lysine-specific histone demethylase 1A | 1 | 0.689 | |
| 1kif | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.688 | |
| 2h94 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.688 | |
| 2iw5 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.688 | |
| 3lzx | FAD | Ferredoxin--NADP reductase 2 | 1.18.1.2 | 0.688 | |
| 5er0 | FAD | Uncharacterized NAD(FAD)-dependent dehydrogenase | / | 0.688 | |
| 1onf | FAD | Glutathione reductase | 1.8.1.7 | 0.687 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.687 | |
| 3up5 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.687 | |
| 4u8l | FDA | UDP-galactopyranose mutase | / | 0.687 | |
| 1kf6 | FAD | Fumarate reductase flavoprotein subunit | 1.3.5.4 | 0.686 | |
| 2eq7 | FAD | Dihydrolipoyl dehydrogenase | / | 0.686 | |
| 4opi | FDA | Conserved Archaeal protein | / | 0.686 | |
| 4rsl | FAD | Fructosyl peptide oxidase | / | 0.686 | |
| 2bra | FAD | [F-actin]-methionine sulfoxide oxidase MICAL1 | 1.14.13 | 0.685 | |
| 1cjc | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.684 | |
| 1fl2 | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.684 | |
| 3sfe | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.684 | |
| 4ylf | FAD | Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit homolog | / | 0.684 | |
| 1w4x | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.683 | |
| 2o06 | MTA | Spermidine synthase | 2.5.1.16 | 0.683 | |
| 3alj | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.683 | |
| 3he3 | FAD | UDP-galactopyranose mutase | / | 0.683 | |
| 3kpf | FAD | Polyamine oxidase | 1.5.3.14 | 0.683 | |
| 3nyc | FAD | FAD-dependent catabolic D-arginine dehydrogenase DauA | / | 0.683 | |
| 3rp8 | FAD | FAD-dependent urate hydroxylase | / | 0.683 | |
| 4a65 | FAD | Thioredoxin reductase | / | 0.683 | |
| 2ywl | FAD | Thioredoxin reductase related protein | / | 0.682 | |
| 2z6c | FMN | Phototropin-1 | 2.7.11.1 | 0.682 | |
| 4dna | FAD | Probable glutathione reductase | / | 0.682 | |
| 4jnq | FDA | Thioredoxin reductase | / | 0.682 | |
| 4tlz | FAD | KtzI | / | 0.682 | |
| 4up3 | FAD | Thioredoxin reductase | / | 0.682 | |
| 2bac | FAD | Putative aminooxidase | / | 0.681 | |
| 2cfy | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.681 | |
| 3d8x | FAD | Thioredoxin reductase 1 | 1.8.1.9 | 0.681 | |
| 2whd | FAD | Thioredoxin reductase | / | 0.680 | |
| 3jsk | AHZ | Thiamine thiazole synthase | / | 0.680 | |
| 3qj4 | FAD | Renalase | / | 0.680 | |
| 4eep | FMN | Phototropin-2 | 2.7.11.1 | 0.680 | |
| 4ntd | FAD | Thioredoxin reductase | / | 0.680 | |
| 4u8n | FDA | UDP-galactopyranose mutase | / | 0.680 | |
| 1n9l | FMN | Putative blue light receptor | / | 0.679 | |
| 1nhp | FAD | NADH peroxidase | 1.11.1.1 | 0.679 | |
| 1ps9 | FAD | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.679 | |
| 2r9z | FAD | Glutathione amide reductase | / | 0.679 | |
| 3dh9 | FAD | Thioredoxin reductase 1, mitochondrial | 1.8.1.9 | 0.679 | |
| 3kkj | FAD | Renalase | / | 0.679 | |
| 4c3x | FAD | 3-ketosteroid dehydrogenase | / | 0.679 | |
| 4j56 | FAD | Thioredoxin reductase 2 | 1.8.1.9 | 0.679 | |
| 4xbf | FAD | Lysine-specific histone demethylase 1A | 1 | 0.679 | |
| 1djn | ADP | Trimethylamine dehydrogenase | 1.5.8.2 | 0.678 | |
| 1djq | ADP | Trimethylamine dehydrogenase | 1.5.8.2 | 0.678 | |
| 2eq7 | NAD | Dihydrolipoyl dehydrogenase | / | 0.678 | |
| 4kx6 | FAD | Fumarate reductase flavoprotein subunit | 1.3.5.4 | 0.678 | |
| 4xwz | FAD | Fructosyl amine:oxygen oxidoreductase | / | 0.678 | |
| 2ylt | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.677 | |
| 3hdy | FAD | UDP-galactopyranose mutase | / | 0.677 | |
| 4ccr | FAD | Thioredoxin reductase | / | 0.677 | |
| 4iv8 | SAM | Phosphoethanolamine N-methyltransferase,putative | / | 0.677 | |
| 4opu | FDA | Conserved Archaeal protein | / | 0.677 | |
| 4tm3 | FAD | KtzI | / | 0.677 | |
| 4x4j | FAD | Putative oxygenase | / | 0.677 | |
| 2hmv | ADP | Ktr system potassium uptake protein A | / | 0.676 | |
| 3lzw | FAD | Ferredoxin--NADP reductase 2 | 1.18.1.2 | 0.676 | |
| 1e1k | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.675 | |
| 1n9n | FMN | Putative blue light receptor | / | 0.675 | |
| 2b9x | FAD | Putative aminooxidase | / | 0.675 | |
| 4yv2 | S4M | Spermidine synthase, putative | / | 0.675 | |
| 3lsm | SFD | Pyranose 2-oxidase | / | 0.674 | |
| 4d03 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.674 | |
| 1zmc | NAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.673 | |
| 2pd7 | FAD | Vivid PAS protein VVD | / | 0.673 | |
| 4yjd | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.673 | |
| 5br7 | FAD | UDP-galactopyranose mutase | / | 0.673 | |
| 5jdz | SAH | Methyl transferase | / | 0.673 | |
| 5je3 | SAH | Methyl transferase | / | 0.673 | |
| 1mok | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.672 | |
| 2c4c | FAD | [F-actin]-methionine sulfoxide oxidase MICAL1 | 1.14.13 | 0.672 | |
| 2ylr | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.672 | |
| 3epp | SFG | mRNA cap guanine-N7 methyltransferase | 2.1.1.56 | 0.672 | |
| 3p9u | FAD | TetX family tetracycline inactivation enzyme | / | 0.672 | |
| 4b65 | FAD | L-ornithine N(5)-monooxygenase | / | 0.672 | |
| 1krh | FAD | Benzoate 1,2-dioxygenase electron transfer component | 1.18.1.3 | 0.671 | |
| 2vou | FAD | 2,6-dihydroxypyridine 3-monooxygenase | 1.14.13.10 | 0.671 | |
| 3ef6 | FAD | Toluene 1,2-dioxygenase system ferredoxin--NAD(+) reductase component | 1.18.1.3 | 0.671 | |
| 3zdn | FAD | Monoamine oxidase N | 1.4.3.4 | 0.671 | |
| 1qg0 | FAD | Ferredoxin--NADP reductase, leaf isozyme, chloroplastic | 1.18.1.2 | 0.670 | |
| 2gmj | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.670 | |
| 3grv | ADN | Probable ribosomal RNA small subunit methyltransferase A | / | 0.670 | |
| 3qfc | FAD | NADPH--cytochrome P450 reductase | / | 0.670 | |
| 4jy2 | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.670 | |
| 5dbj | FAD | FADH2-dependent halogenase PltA | / | 0.670 | |
| 2xvi | FAD | Putative flavin-containing monooxygenase | / | 0.669 | |
| 2zth | SAM | Catechol O-methyltransferase | 2.1.1.6 | 0.669 | |
| 4aos | FAD | Steroid monooxygenase | / | 0.669 | |
| 4bk2 | FAD | Probable salicylate monooxygenase | / | 0.669 | |
| 4lii | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.669 | |
| 4wuj | FMN | Glycoside hydrolase family 15, cellulose signaling associated protein envoy | / | 0.669 | |
| 4wx1 | FDA | UDP-galactopyranose mutase | / | 0.669 | |
| 2ard | FDA | Flavin-dependent tryptophan halogenase PrnA | 1.14.19.9 | 0.668 | |
| 2pr5 | FMN | Blue-light photoreceptor | / | 0.668 | |
| 3is2 | FAD | Vivid PAS protein VVD | / | 0.668 | |
| 4dsh | FDA | Uncharacterized protein | / | 0.668 | |
| 4kuk | RBF | Putative blue-light photoreceptor | / | 0.668 | |
| 1a8p | FAD | Ferredoxin--NADP reductase | / | 0.667 | |
| 2rgh | FAD | Alpha-Glycerophosphate Oxidase | / | 0.667 | |
| 3k30 | ADP | Histamine dehydrogenase | / | 0.667 | |
| 4b1b | FAD | Thioredoxin reductase | 1.8.1.9 | 0.667 | |
| 4ysh | FAD | Glycine oxidase | / | 0.667 | |
| 5eow | FAD | 6-hydroxynicotinate 3-monooxygenase | 1.14.13.114 | 0.667 | |
| 1tdn | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.666 | |
| 2qa2 | FAD | Polyketide oxygenase CabE | / | 0.666 | |
| 2wp5 | FAD | Trypanothione reductase | / | 0.666 | |
| 2ylw | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.666 | |
| 4z43 | FAD | Flavin-dependent tryptophan halogenase PrnA | 1.14.19.9 | 0.666 | |
| 5fs6 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.666 | |
| 2vq7 | FAD | Putative flavin-containing monooxygenase | / | 0.665 | |
| 3m12 | FAD | Monomeric sarcosine oxidase | 1.5.3.1 | 0.665 | |
| 4h4r | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.665 | |
| 2eq8 | FAD | Dihydrolipoyl dehydrogenase | / | 0.664 | |
| 3ab1 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.664 | |
| 4h4z | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.664 | |
| 4hnb | FMN | LOV protein | / | 0.664 | |
| 1m6i | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.663 | |
| 1r2j | FAD | FkbI | / | 0.663 | |
| 2x3n | FAD | Probable FAD-dependent monooxygenase | / | 0.663 | |
| 3hdy | FDA | UDP-galactopyranose mutase | / | 0.663 | |
| 3sz0 | FAD | Sulfide-quinone reductase | / | 0.663 | |
| 4a6n | FAD | TetX family tetracycline inactivation enzyme | / | 0.663 | |
| 4eer | FMN | Phototropin-2 | 2.7.11.1 | 0.663 | |
| 4icy | FAD | PgaE | / | 0.663 | |
| 4jdr | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.663 | |
| 4u8k | FDA | UDP-galactopyranose mutase | / | 0.663 | |
| 1grg | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.662 | |
| 2ji9 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.662 | |
| 3ad9 | FAD | Subunit beta of sarcosine oxidase | / | 0.662 | |
| 3f8p | NAD | NADH oxidase/thioredoxin reductase | / | 0.662 | |
| 3m13 | FAD | Monomeric sarcosine oxidase | 1.5.3.1 | 0.662 | |
| 3t50 | FMN | Blue-light-activated histidine kinase | 2.7.13.3 | 0.662 | |
| 1ojt | FAD | Dihydrolipoyl dehydrogenase | / | 0.661 | |
| 2z1q | FAD | Acyl-CoA dehydrogenase | / | 0.661 | |
| 4x9n | FAD | Uncharacterized protein MG039 homolog | / | 0.661 | |
| 2gr0 | FAD | Ferredoxin reductase | / | 0.660 | |
| 3dk8 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.660 | |
| 3vqr | FAD | Putative oxidoreductase | / | 0.660 | |
| 2pdt | FAD | Vivid PAS protein VVD | / | 0.659 | |
| 2qae | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.659 | |
| 3bnk | FMN | Flavoredoxin | / | 0.659 | |
| 3duw | SAH | O-methyltransferase, putative | / | 0.659 | |
| 3p7n | FMN | Light-activated DNA-binding protein EL222 | / | 0.659 | |
| 4ees | FMN | Phototropin-2 | 2.7.11.1 | 0.659 | |
| 2uxx | FAJ | Lysine-specific histone demethylase 1A | 1 | 0.658 | |
| 3fbs | FAD | Oxidoreductase | / | 0.658 | |
| 3fg2 | FAD | Putative rubredoxin reductase | / | 0.658 | |
| 4hia | FMN | LOV protein | / | 0.658 | |
| 1lvl | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.657 | |
| 2cdu | ADP | NADH oxidase | / | 0.657 | |
| 3cty | FAD | Probable thioredoxin reductase | / | 0.657 | |
| 3ukk | FAD | UDP-galactopyranose mutase | / | 0.657 | |
| 3uox | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.657 | |
| 4nwz | FAD | FAD-dependent pyridine nucleotide-disulfide oxidoreductase | / | 0.657 | |
| 5fs8 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.657 | |
| 2yyi | FAD | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component | 1.14.14.9 | 0.656 | |
| 3hji | FAD | Vivid PAS protein VVD | / | 0.656 | |
| 3ute | FAD | UDP-galactopyranose mutase | / | 0.656 | |
| 4r38 | RBF | Blue-light-activated histidine kinase 2 | 2.7.13.3 | 0.656 | |
| 4yuz | S4M | Spermidine synthase, putative | / | 0.656 | |
| 3dk9 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.655 | |
| 3nt6 | FAD | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.655 | |
| 3qe2 | FAD | NADPH--cytochrome P450 reductase | / | 0.655 | |
| 3znp | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.655 | |
| 1d4d | FAD | Fumarate reductase flavoprotein subunit | 1.3.5.4 | 0.654 | |
| 2qa1 | FAD | PgaE | / | 0.654 | |
| 3cgd | FAD | Coenzyme A disulfide reductase | / | 0.654 | |
| 3uj8 | SFG | Phosphoethanolamine N-methyltransferase | / | 0.654 | |
| 4eet | FMN | Phototropin-2 | 2.7.11.1 | 0.654 | |
| 4pyo | SAH | Catechol O-methyltransferase | 2.1.1.6 | 0.654 | |
| 4tm0 | FAD | KtzI | / | 0.654 | |
| 2a1u | FAD | Electron transfer flavoprotein subunit alpha, mitochondrial | / | 0.653 | |
| 2p35 | SAH | Trans-aconitate 2-methyltransferase | / | 0.653 | |
| 2tmd | ADP | Trimethylamine dehydrogenase | 1.5.8.2 | 0.653 | |
| 1iqr | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.652 | |
| 1npx | FAD | NADH peroxidase | 1.11.1.1 | 0.652 | |
| 4a5l | FAD | Thioredoxin reductase | / | 0.652 | |
| 4guu | FA9 | Lysine-specific histone demethylase 1B | 1 | 0.652 | |
| 4i58 | FAD | Cyclohexylamine Oxidase | / | 0.652 | |
| 4nmb | FAD | Bifunctional protein PutA | / | 0.652 | |
| 7mht | SAH | Modification methylase HhaI | 2.1.1.37 | 0.652 | |
| 1typ | FAD | Trypanothione reductase | 1.8.1.12 | 0.651 | |
| 4gde | FDA | UDP-galactopyranose mutase | / | 0.651 | |
| 4usq | FAD | Pyridine nucleotide-disulfide oxidoreductase | / | 0.651 | |
| 1geg | NAD | Diacetyl reductase [(S)-acetoin forming] | 1.1.1.304 | 0.650 | |
| 5cho | FAD | Flavin reductase | / | 0.650 |