sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1lpf | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 1lpf | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 1.352 | |
| 2qae | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 1.109 | |
| 3rnm | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 1.080 | |
| 2eq7 | FAD | Dihydrolipoyl dehydrogenase | / | 1.067 | |
| 1zmd | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 1.059 | |
| 2yqu | FAD | Dihydrolipoyl dehydrogenase | / | 1.042 | |
| 2eq8 | FAD | Dihydrolipoyl dehydrogenase | / | 1.040 | |
| 2eq6 | FAD | Dihydrolipoyl dehydrogenase | / | 1.035 | |
| 1zmc | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 1.025 | |
| 3lad | FAD | Dihydrolipoyl dehydrogenase | / | 1.016 | |
| 1jeh | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 1.012 | |
| 4jdr | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 1.002 | |
| 3urh | FAD | Dihydrolipoyl dehydrogenase | / | 0.999 | |
| 2f5z | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.996 | |
| 1v59 | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.955 | |
| 2eq9 | FAD | Dihydrolipoyl dehydrogenase | / | 0.949 | |
| 3grs | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.944 | |
| 1ebd | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.934 | |
| 3dk9 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.931 | |
| 1ger | FAD | Glutathione reductase | 1.8.1.7 | 0.925 | |
| 4jq9 | FAD | Dihydrolipoyl dehydrogenase | / | 0.917 | |
| 3djj | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.913 | |
| 1grb | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.903 | |
| 2a8x | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.890 | |
| 4gr1 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.887 | |
| 4m52 | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.880 | |
| 3sqp | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.872 | |
| 2x8h | FAD | Thioredoxin glutathione reductase | / | 0.866 | |
| 1gra | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.863 | |
| 2nvk | FAD | Thioredoxin reductase 1, mitochondrial | 1.8.1.9 | 0.861 | |
| 3dk4 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.861 | |
| 1gsn | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.858 | |
| 1k4q | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.858 | |
| 1gre | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.855 | |
| 3dh9 | FAD | Thioredoxin reductase 1, mitochondrial | 1.8.1.9 | 0.850 | |
| 2r9z | FAD | Glutathione amide reductase | / | 0.849 | |
| 2wow | FAD | Trypanothione reductase | / | 0.848 | |
| 1npx | FAD | NADH peroxidase | 1.11.1.1 | 0.843 | |
| 1zk7 | FAD | Mercuric reductase | 1.16.1.1 | 0.842 | |
| 2npx | FAD | NADH peroxidase | 1.11.1.1 | 0.842 | |
| 4b1b | FAD | Thioredoxin reductase | 1.8.1.9 | 0.840 | |
| 1xdi | FAD | NAD(P)H dehydrogenase (quinone) | / | 0.839 | |
| 1bwc | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.834 | |
| 1ges | FAD | Glutathione reductase | 1.8.1.7 | 0.834 | |
| 1grh | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.832 | |
| 2zzc | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.832 | |
| 1zy8 | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.828 | |
| 1lvl | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.827 | |
| 1nhs | FAD | NADH peroxidase | 1.11.1.1 | 0.826 | |
| 2jk6 | FAD | Trypanothione reductase | / | 0.826 | |
| 3djg | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.825 | |
| 1get | FAD | Glutathione reductase | 1.8.1.7 | 0.823 | |
| 1geu | FAD | Glutathione reductase | 1.8.1.7 | 0.822 | |
| 3dk8 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.822 | |
| 3ean | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.822 | |
| 2hqm | FAD | Glutathione reductase | 1.8.1.7 | 0.819 | |
| 1ojt | FAD | Dihydrolipoyl dehydrogenase | / | 0.816 | |
| 1zx9 | FAD | Mercuric reductase | 1.16.1.1 | 0.816 | |
| 4kpr | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.814 | |
| 4j56 | FAD | Thioredoxin reductase 2 | 1.8.1.9 | 0.810 | |
| 1nhp | FAD | NADH peroxidase | 1.11.1.1 | 0.806 | |
| 1fec | FAD | Trypanothione reductase | 1.8.1.12 | 0.805 | |
| 3dgh | FAD | Thioredoxin reductase 1, mitochondrial | 1.8.1.9 | 0.802 | |
| 2x8g | FAD | Thioredoxin glutathione reductase | / | 0.800 | |
| 3lzx | FAD | Ferredoxin--NADP reductase 2 | 1.18.1.2 | 0.800 | |
| 3oc4 | FAD | Oxidoreductase, pyridine nucleotide-disulfide family | / | 0.796 | |
| 2i0z | FAD | NAD(FAD)-utilizing dehydrogenases | / | 0.795 | |
| 2rab | FAD | Glutathione amide reductase | / | 0.795 | |
| 2zbw | FAD | Ferredoxin--NADP reductase | / | 0.794 | |
| 3qfa | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.793 | |
| 3ics | FAD | Coenzyme A disulfide reductase | / | 0.788 | |
| 4nev | FAD | Trypanothione reductase | / | 0.787 | |
| 2tpr | FAD | Trypanothione reductase | 1.8.1.12 | 0.786 | |
| 2j3n | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.784 | |
| 2wba | FAD | Trypanothione reductase | 1.8.1.12 | 0.784 | |
| 1nhr | FAD | NADH peroxidase | 1.11.1.1 | 0.782 | |
| 2v6o | FAD | Thioredoxin glutathione reductase | / | 0.782 | |
| 1fea | FAD | Trypanothione reductase | 1.8.1.12 | 0.781 | |
| 2gh5 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.780 | |
| 1feb | FAD | Trypanothione reductase | 1.8.1.12 | 0.779 | |
| 1dnc | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.776 | |
| 1typ | FAD | Trypanothione reductase | 1.8.1.12 | 0.770 | |
| 1tyt | FAD | Trypanothione reductase | 1.8.1.12 | 0.768 | |
| 1tde | FAD | Thioredoxin reductase | 1.8.1.9 | 0.767 | |
| 3fbs | FAD | Oxidoreductase | / | 0.767 | |
| 1mo9 | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.766 | |
| 2qa1 | FAD | PgaE | / | 0.764 | |
| 1grg | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.762 | |
| 2cfy | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.762 | |
| 3lzw | FAD | Ferredoxin--NADP reductase 2 | 1.18.1.2 | 0.762 | |
| 1onf | FAD | Glutathione reductase | 1.8.1.7 | 0.761 | |
| 2wp5 | FAD | Trypanothione reductase | / | 0.759 | |
| 1bzl | FAD | Trypanothione reductase | 1.8.1.12 | 0.757 | |
| 3ntd | FAD | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.757 | |
| 3nta | FAD | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.754 | |
| 4j57 | FAD | Thioredoxin reductase 2 | 1.8.1.9 | 0.754 | |
| 3ict | FAD | Coenzyme A disulfide reductase | / | 0.751 | |
| 4cnk | FAD | L-amino acid oxidase | / | 0.751 | |
| 3oz2 | FAD | Digeranylgeranylglycerophospholipid reductase | / | 0.750 | |
| 4dna | FAD | Probable glutathione reductase | / | 0.747 | |
| 1gxf | FAD | Trypanothione reductase | 1.8.1.12 | 0.746 | |
| 3ab1 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.746 | |
| 4fwf | FAD | Lysine-specific histone demethylase 1B | 1 | 0.746 | |
| 4jnq | FDA | Thioredoxin reductase | / | 0.746 | |
| 4j36 | FAD | Kynurenine 3-monooxygenase | / | 0.744 | |
| 4k2x | FAD | Polyketide oxygenase/hydroxylase | / | 0.743 | |
| 4x4j | FAD | Putative oxygenase | / | 0.743 | |
| 1f8w | FAD | NADH peroxidase | 1.11.1.1 | 0.742 | |
| 4j31 | FAD | Kynurenine 3-monooxygenase | / | 0.742 | |
| 4j34 | FAD | Kynurenine 3-monooxygenase | / | 0.742 | |
| 2c3c | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.740 | |
| 2zz0 | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.739 | |
| 4hb9 | FAD | Uncharacterized protein | / | 0.739 | |
| 4j33 | FAD | Kynurenine 3-monooxygenase | / | 0.737 | |
| 1trb | FAD | Thioredoxin reductase | 1.8.1.9 | 0.735 | |
| 3v76 | FDA | Uncharacterized protein | / | 0.734 | |
| 5buk | FAD | FADH2-dependent halogenase | / | 0.732 | |
| 3ef6 | FAD | Toluene 1,2-dioxygenase system ferredoxin--NAD(+) reductase component | 1.18.1.3 | 0.728 | |
| 4icy | FAD | PgaE | / | 0.728 | |
| 2c3d | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.727 | |
| 4u2t | FAD | Cholesterol oxidase | 1.1.3.6 | 0.727 | |
| 3ic9 | FAD | Putative dihydrolipoamide dehydrogenase | / | 0.724 | |
| 3qfb | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.724 | |
| 4j2w | FAD | Kynurenine 3-monooxygenase | / | 0.724 | |
| 5eow | FAD | 6-hydroxynicotinate 3-monooxygenase | 1.14.13.114 | 0.724 | |
| 3g5q | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.722 | |
| 4h4p | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.720 | |
| 4opu | FDA | Conserved Archaeal protein | / | 0.719 | |
| 2vou | FAD | 2,6-dihydroxypyridine 3-monooxygenase | 1.14.13.10 | 0.718 | |
| 3itj | FAD | Thioredoxin reductase 1 | 1.8.1.9 | 0.718 | |
| 4jy2 | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.718 | |
| 4ntc | FAD | Thioredoxin reductase gliT | / | 0.718 | |
| 1h6v | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.717 | |
| 3ad9 | NAD | Subunit alpha of sarocosine oxidase | / | 0.717 | |
| 3bg7 | FAD | Pyranose 2-oxidase | / | 0.717 | |
| 1rp0 | AHZ | Thiamine thiazole synthase, chloroplastic | / | 0.716 | |
| 4cnj | FAD | L-amino acid oxidase | / | 0.714 | |
| 2yg4 | FAD | Putrescine oxidase | / | 0.713 | |
| 2q7v | FAD | Thioredoxin reductase | / | 0.712 | |
| 3ish | FAD | Thioredoxin reductase | 1.8.1.9 | 0.712 | |
| 4dsh | FDA | Uncharacterized protein | / | 0.711 | |
| 3alj | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.710 | |
| 2q0k | FAD | Thioredoxin reductase | 1.8.1.9 | 0.708 | |
| 4bk2 | FAD | Probable salicylate monooxygenase | / | 0.708 | |
| 2x3n | FAD | Probable FAD-dependent monooxygenase | / | 0.707 | |
| 4gcm | FAD | Thioredoxin reductase | 1.8.1.9 | 0.707 | |
| 4h2p | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.707 | |
| 4opl | FDA | Conserved Archaeal protein | / | 0.706 | |
| 2gew | FAD | Cholesterol oxidase | 1.1.3.6 | 0.705 | |
| 4opi | FDA | Conserved Archaeal protein | / | 0.705 | |
| 4opt | FDA | Conserved Archaeal protein | / | 0.705 | |
| 3atr | FDA | Conserved Archaeal protein | / | 0.704 | |
| 4h4t | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.704 | |
| 4i58 | FAD | Cyclohexylamine Oxidase | / | 0.704 | |
| 4h4v | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.703 | |
| 4lii | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.703 | |
| 4o5q | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.703 | |
| 2yg5 | FAD | Putrescine oxidase | / | 0.702 | |
| 4bjz | FAD | Probable salicylate monooxygenase | / | 0.702 | |
| 4la1 | FAD | Thioredoxin glutathione reductase | / | 0.702 | |
| 4h4r | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.701 | |
| 5fs6 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.701 | |
| 4em3 | FAD | Coenzyme A disulfide reductase | / | 0.700 | |
| 4h4x | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.700 | |
| 4opg | FDA | Conserved Archaeal protein | / | 0.700 | |
| 2igo | FAD | Pyranose 2-oxidase | / | 0.699 | |
| 1d4c | FAD | Fumarate reductase flavoprotein subunit | 1.3.5.4 | 0.698 | |
| 1joa | FAD | NADH peroxidase | 1.11.1.1 | 0.698 | |
| 2bra | FAD | [F-actin]-methionine sulfoxide oxidase MICAL1 | 1.14.13 | 0.698 | |
| 2w0h | FAD | Trypanothione reductase | / | 0.698 | |
| 2ylz | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.698 | |
| 4c3x | FAD | 3-ketosteroid dehydrogenase | / | 0.698 | |
| 4dsg | FAD | Uncharacterized protein | / | 0.698 | |
| 3atq | FDA | Conserved Archaeal protein | / | 0.697 | |
| 3lsi | FAD | Pyranose 2-oxidase | / | 0.697 | |
| 3all | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.696 | |
| 4ccr | FAD | Thioredoxin reductase | / | 0.696 | |
| 4em4 | FAD | Coenzyme A disulfide reductase | / | 0.696 | |
| 4fwe | FAD | Lysine-specific histone demethylase 1B | 1 | 0.696 | |
| 4cbq | FAD | Thioredoxin reductase | / | 0.695 | |
| 3g5s | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.694 | |
| 4o5u | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.693 | |
| 1d7y | FAD | Ferredoxin reductase | / | 0.692 | |
| 2xdo | FAD | TetX family tetracycline inactivation enzyme | / | 0.692 | |
| 3cty | FAD | Probable thioredoxin reductase | / | 0.692 | |
| 4mih | FAD | Pyranose 2-oxidase | 1.1.3.10 | 0.692 | |
| 1gv4 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.691 | |
| 1mxt | FAE | Cholesterol oxidase | 1.1.3.6 | 0.691 | |
| 4xxg | FAD | Cholesterol oxidase | 1.1.3.6 | 0.691 | |
| 5fs9 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.691 | |
| 4a6n | FAD | TetX family tetracycline inactivation enzyme | / | 0.690 | |
| 4bk3 | FAD | Probable salicylate monooxygenase | / | 0.690 | |
| 4fk1 | FAD | Putative thioredoxin reductase | / | 0.690 | |
| 4mok | FAD | Pyranose 2-oxidase | / | 0.689 | |
| 3lsm | SFD | Pyranose 2-oxidase | / | 0.688 | |
| 4bv6 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.688 | |
| 3mj4 | FAD | UDP-galactopyranose mutase | / | 0.687 | |
| 4gut | FAD | Lysine-specific histone demethylase 1B | 1 | 0.687 | |
| 4ntd | FAD | Thioredoxin reductase | / | 0.686 | |
| 2whd | FAD | Thioredoxin reductase | / | 0.685 | |
| 3k7m | FAD | 6-hydroxy-L-nicotine oxidase | / | 0.685 | |
| 3cgb | FAD | Coenzyme A disulfide reductase | / | 0.684 | |
| 1pkv | RBF | Riboflavin synthase | 2.5.1.9 | 0.683 | |
| 1tdf | FAD | Thioredoxin reductase | 1.8.1.9 | 0.683 | |
| 2b9x | FAD | Putative aminooxidase | / | 0.683 | |
| 3r9u | FAD | Thioredoxin reductase | / | 0.683 | |
| 4k5r | FAD | Oxygenase | / | 0.683 | |
| 2gqw | FAD | Ferredoxin reductase | / | 0.682 | |
| 2ign | FAD | Pyranose 2-oxidase | / | 0.682 | |
| 3f8d | FAD | NADH oxidase/thioredoxin reductase | / | 0.682 | |
| 4a65 | FAD | Thioredoxin reductase | / | 0.682 | |
| 4ccq | FAD | Thioredoxin reductase | / | 0.682 | |
| 3fmw | FAD | Oxygenase | / | 0.681 | |
| 4h4z | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.681 | |
| 1ve9 | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.680 | |
| 2c7g | FAD | NADPH-ferredoxin reductase FprA | 1.18.1.2 | 0.680 | |
| 2xyo | FAD | TetX family tetracycline inactivation enzyme | / | 0.680 | |
| 4a99 | FAD | TetX family tetracycline inactivation enzyme | / | 0.680 | |
| 2q0l | FAD | Thioredoxin reductase | 1.8.1.9 | 0.679 | |
| 3gmb | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.679 | |
| 3he3 | FAD | UDP-galactopyranose mutase | / | 0.679 | |
| 4a5l | FAD | Thioredoxin reductase | / | 0.679 | |
| 2gmh | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.678 | |
| 3dgz | FAD | Thioredoxin reductase 2, mitochondrial | 1.8.1.9 | 0.678 | |
| 3l8k | ADP | Dihydrolipoamide dehydrogenase (PdhD-3) | / | 0.677 | |
| 4eqr | FAD | Coenzyme A disulfide reductase | / | 0.677 | |
| 4nte | FAD | DepH | / | 0.677 | |
| 4up3 | FAD | Thioredoxin reductase | / | 0.677 | |
| 1n1p | FAD | Cholesterol oxidase | 1.1.3.6 | 0.676 | |
| 1n4w | FAD | Cholesterol oxidase | 1.1.3.6 | 0.676 | |
| 1lqu | FAD | NADPH-ferredoxin reductase FprA | 1.18.1.2 | 0.675 | |
| 1vdc | FAD | Thioredoxin reductase 1, mitochondrial | 1.8.1.9 | 0.675 | |
| 2qa2 | FAD | Polyketide oxygenase CabE | / | 0.675 | |
| 3cge | FAD | Coenzyme A disulfide reductase | / | 0.675 | |
| 3rha | FDA | Putrescine oxidase | / | 0.675 | |
| 1djn | ADP | Trimethylamine dehydrogenase | 1.5.8.2 | 0.674 | |
| 1m6i | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.674 | |
| 1n4v | FAD | Cholesterol oxidase | 1.1.3.6 | 0.674 | |
| 2wes | FAD | Tryptophan 5-halogenase | / | 0.674 | |
| 3klj | FAD | NADH-rubredoxin oxidoreductase | 1.18.1.1 | 0.673 | |
| 4fwj | FAD | Lysine-specific histone demethylase 1B | 1 | 0.673 | |
| 4h2n | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.673 | |
| 1yqz | FAD | Coenzyme A disulfide reductase | / | 0.672 | |
| 1djq | ADP | Trimethylamine dehydrogenase | 1.5.8.2 | 0.671 | |
| 2aqj | FAD | Flavin-dependent tryptophan halogenase PrnA | 1.14.19.9 | 0.671 | |
| 2gr0 | FAD | Ferredoxin reductase | / | 0.671 | |
| 3alm | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.671 | |
| 1e1k | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.670 | |
| 1ijh | FAD | Cholesterol oxidase | 1.1.3.6 | 0.670 | |
| 1pdh | FAS | p-hydroxybenzoate hydroxylase | / | 0.669 | |
| 4gur | FAD | Lysine-specific histone demethylase 1B | 1 | 0.669 | |
| 2cdu | FAD | NADH oxidase | / | 0.668 | |
| 3cgc | FAD | Coenzyme A disulfide reductase | / | 0.668 | |
| 3d8x | FAD | Thioredoxin reductase 1 | 1.8.1.9 | 0.668 | |
| 3k30 | ADP | Histamine dehydrogenase | / | 0.668 | |
| 2yvf | FAD | Ferredoxin reductase | / | 0.667 | |
| 3gwd | FAD | Cyclohexanone monooxygenase | / | 0.667 | |
| 1ryi | FAD | Glycine oxidase | 1.4.3.19 | 0.666 | |
| 2bac | FAD | Putative aminooxidase | / | 0.666 | |
| 2b9y | FAD | Putative aminooxidase | / | 0.665 | |
| 1o94 | ADP | Trimethylamine dehydrogenase | 1.5.8.2 | 0.664 | |
| 2tmd | ADP | Trimethylamine dehydrogenase | 1.5.8.2 | 0.664 | |
| 3ept | FDA | Putative FAD-monooxygenase | / | 0.664 | |
| 5br7 | FAD | UDP-galactopyranose mutase | / | 0.664 | |
| 2ba9 | FAD | Putative aminooxidase | / | 0.663 | |
| 3p9u | FAD | TetX family tetracycline inactivation enzyme | / | 0.663 | |
| 4tm4 | FDA | KtzI | / | 0.663 | |
| 3c4a | FAD | Protodeoxyviolaceinate monooxygenase | 1 | 0.662 | |
| 4eqs | FAD | Coenzyme A disulfide reductase | / | 0.662 | |
| 4ocg | FAD | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.662 | |
| 4rek | FAD | Cholesterol oxidase | 1.1.3.6 | 0.662 | |
| 1fl2 | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.661 | |
| 1ju2 | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.661 | |
| 3ad9 | FAD | Subunit beta of sarcosine oxidase | / | 0.660 | |
| 4u2l | SFD | Cholesterol oxidase | 1.1.3.6 | 0.660 | |
| 5g3s | FDA | Flavin-dependent L-tryptophan oxidase VioA | / | 0.660 | |
| 1tdo | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.659 | |
| 2ywl | FAD | Thioredoxin reductase related protein | / | 0.659 | |
| 3gsi | FAD | Dimethylglycine oxidase | 1.5.3.10 | 0.659 | |
| 1k0j | FAD | p-hydroxybenzoate hydroxylase | / | 0.657 | |
| 1mok | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.657 | |
| 2byc | FMN | Blue-light receptor of the BLUF-family | / | 0.657 | |
| 3b6d | FAE | Cholesterol oxidase | 1.1.3.6 | 0.657 | |
| 4ynt | FDA | Glucose oxidase, putative | / | 0.657 | |
| 1e1m | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.656 | |
| 2fja | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.656 | |
| 4ech | FAD | Polyamine oxidase FMS1 | / | 0.656 | |
| 4g6g | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.656 | |
| 2yg3 | FAD | Putrescine oxidase | / | 0.655 | |
| 3k4c | FAD | Pyranose 2-oxidase | / | 0.655 | |
| 4bur | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.655 | |
| 4qi4 | FAD | Cellobiose dehydrogenase | / | 0.655 | |
| 4u8m | FDA | UDP-galactopyranose mutase | / | 0.655 | |
| 1d7l | RFL | p-hydroxybenzoate hydroxylase | / | 0.654 | |
| 3utf | FDA | UDP-galactopyranose mutase | / | 0.654 | |
| 4wct | FAD | Fructosyl amine:oxygen oxidoreductase | / | 0.654 | |
| 1nhq | FAD | NADH peroxidase | 1.11.1.1 | 0.653 | |
| 4nwz | FAD | FAD-dependent pyridine nucleotide-disulfide oxidoreductase | / | 0.653 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.652 | |
| 4gus | FAD | Lysine-specific histone demethylase 1B | 1 | 0.652 | |
| 2gqf | FAD | Uncharacterized protein HI_0933 | / | 0.651 | |
| 3fcj | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.651 | |
| 3lb8 | FAD | Putidaredoxin reductase | 1.18.1.5 | 0.651 | |
| 3vqr | FAD | Putative oxidoreductase | / | 0.651 | |
| 2reh | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.650 | |
| 2xvi | FAD | Putative flavin-containing monooxygenase | / | 0.650 | |
| 3gdp | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.650 | |
| 3kpf | FAD | Polyamine oxidase | 1.5.3.14 | 0.650 | |
| 3nt6 | FAD | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.650 |