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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4fod0UVALK tyrosine kinase receptor2.7.10.1

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
4fod0UVALK tyrosine kinase receptor2.7.10.11.000
4fob0USALK tyrosine kinase receptor2.7.10.10.634
4foc0UUALK tyrosine kinase receptor2.7.10.10.571
2xb7GUIALK tyrosine kinase receptor2.7.10.10.559
2xp2VGHALK tyrosine kinase receptor2.7.10.10.534
4aojV4ZHigh affinity nerve growth factor receptor2.7.10.10.534
3cblSTUTyrosine-protein kinase Fes/Fps2.7.10.20.530
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.527
3pxkPXKFocal adhesion kinase 12.7.10.20.521
3uyt0CKCasein kinase I isoform delta2.7.11.10.520
3lctADPALK tyrosine kinase receptor2.7.10.10.517
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.516
2j0m4STFocal adhesion kinase 12.7.10.20.515
4qmtH1NSerine/threonine-protein kinase 242.7.11.10.511
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.511
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.508
3bkbSTUTyrosine-protein kinase Fes/Fps2.7.10.20.508
3hrfATP3-phosphoinositide-dependent protein kinase 12.7.11.10.508
4a06ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.506
3cd3STUTyrosine-protein kinase Fes/Fps2.7.10.20.505
3sc13S13-phosphoinositide-dependent protein kinase 12.7.11.10.505
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.505
4y93746Tyrosine-protein kinase/0.505
4c61LMMTyrosine-protein kinase JAK2/0.504
4i22IREEpidermal growth factor receptor2.7.10.10.504
5aacVGHALK tyrosine kinase receptor2.7.10.10.503
3nuuJOZ3-phosphoinositide-dependent protein kinase 12.7.11.10.501
2xa4AZ5Tyrosine-protein kinase JAK2/0.500
3vw6IM6Mitogen-activated protein kinase kinase kinase 52.7.11.250.500
4e93GUITyrosine-protein kinase Fes/Fps2.7.10.20.500
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.499
5aaaVGHALK tyrosine kinase receptor2.7.10.10.499
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.498
4qmzB49Serine/threonine-protein kinase 242.7.11.10.498
5ackATP3-phosphoinositide-dependent protein kinase 12.7.11.10.498
2b7aIZATyrosine-protein kinase JAK2/0.497
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.497
3ma301ISerine/threonine-protein kinase pim-12.7.11.10.497
3t8oATPRhodopsin kinase/0.497
3gubGUBDeath-associated protein kinase 12.7.11.10.496
2bfyH1NAurora kinase B-A2.7.11.10.495
2brhDFWSerine/threonine-protein kinase Chk12.7.11.10.495
2pe039Z3-phosphoinositide-dependent protein kinase 12.7.11.10.495
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.495
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.493
4fv1EK4Mitogen-activated protein kinase 12.7.11.240.493
4rqkATP3-phosphoinositide-dependent protein kinase 12.7.11.10.493
2x2mX2MProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.491
2xk9XK9Serine/threonine-protein kinase Chk22.7.11.10.491
2j0lANPFocal adhesion kinase 12.7.10.20.490
2wtiWTISerine/threonine-protein kinase Chk22.7.11.10.490
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.490
2qo9ANPEphrin type-A receptor 32.7.10.10.489
2wmuZYUSerine/threonine-protein kinase Chk12.7.11.10.489
2yitYITSerine/threonine-protein kinase Chk22.7.11.10.489
5e8xSTUTGF-beta receptor type-12.7.11.300.489
2jkqVG8Focal adhesion kinase 12.7.10.20.488
3eyhIZATyrosine-protein kinase JAK1/0.487
4bdcODHSerine/threonine-protein kinase Chk22.7.11.10.487
4c62XWWTyrosine-protein kinase JAK2/0.487
4lopSB4Mitogen-activated protein kinase 14/0.487
4nk92K5Fibroblast growth factor receptor 1/0.487
4riyADPEpidermal growth factor receptor2.7.10.10.487
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.486
2w0jZATSerine/threonine-protein kinase Chk22.7.11.10.486
2ydiYDISerine/threonine-protein kinase Chk12.7.11.10.485
4ct1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.485
1qcfPP1Tyrosine-protein kinase HCK2.7.10.20.484
2wmqZYQSerine/threonine-protein kinase Chk12.7.11.10.484
2wmtZYTSerine/threonine-protein kinase Chk12.7.11.10.484
4anqVGHALK tyrosine kinase receptor2.7.10.10.484
4bb432WEphrin type-B receptor 42.7.10.10.484
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.483
3sheI85MAP kinase-activated protein kinase 32.7.11.10.483
4ewhT77Activated CDC42 kinase 1/0.483
2c3lIDZSerine/threonine-protein kinase Chk12.7.11.10.482
2wtcVGMSerine/threonine-protein kinase Chk22.7.11.10.482
2yfxVGHALK tyrosine kinase receptor2.7.10.10.482
4u9aSTUInterleukin-1 receptor-associated kinase 42.7.11.10.482
3iok1P6Tyrosine-protein kinase JAK2/0.481
4rqvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.481
2ijmATPFocal adhesion kinase 12.7.10.20.480
2w7xD1ASerine/threonine-protein kinase Chk22.7.11.10.479
2xvdAS6Ephrin type-B receptor 42.7.10.10.479
2ycqUPXSerine/threonine-protein kinase Chk22.7.11.10.478
3rvg17PTyrosine-protein kinase JAK2/0.478
4bdfH3RSerine/threonine-protein kinase Chk22.7.11.10.478
4ft0HK9Serine/threonine-protein kinase Chk12.7.11.10.478
5e8wSTUTGF-beta receptor type-12.7.11.300.478
2ivuZD6Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.477
2vgoAD5Aurora kinase B-A2.7.11.10.477
2xchCKG3-phosphoinositide-dependent protein kinase 12.7.11.10.477
2ym7YM7Serine/threonine-protein kinase Chk12.7.11.10.477
4bidIE8Mitogen-activated protein kinase kinase kinase 52.7.11.250.477
2xm9LWHSerine/threonine-protein kinase Chk22.7.11.10.476
3nlb5BESerine/threonine-protein kinase Chk12.7.11.10.476
4b99R4LMitogen-activated protein kinase 72.7.11.240.476
4rrvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.476
2brgDFYSerine/threonine-protein kinase Chk12.7.11.10.475
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.475
3hl7I47Mitogen-activated protein kinase 14/0.475
4g6nEK0Mitogen-activated protein kinase 12.7.11.240.475
4mf029ZTyrosine-protein kinase ITK/TSK2.7.10.20.475
1vjy460TGF-beta receptor type-12.7.11.300.474
1xjdSTUProtein kinase C theta type2.7.11.130.474
2e9p77ASerine/threonine-protein kinase Chk12.7.11.10.474
2etm7PYFocal adhesion kinase 12.7.10.20.474
3v5j0F2Tyrosine-protein kinase ITK/TSK2.7.10.20.474
3vs6VSHTyrosine-protein kinase HCK2.7.10.20.474
4ct2ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.474
4gmy0X5Tyrosine-protein kinase JAK2/0.474
4mvfSTUCalcium-dependent protein kinase 22.7.11.10.474
1pmn984Mitogen-activated protein kinase 102.7.11.240.473
2cdz23DSerine/threonine-protein kinase PAK 42.7.11.10.473
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.473
3hrcATP3-phosphoinositide-dependent protein kinase 12.7.11.10.473
3nxe2NCProtease/0.473
4jqeANPCasein kinase II subunit alpha2.7.11.10.473
1eh4IC1Casein kinase I homolog 12.7.11.10.472
1yhsSTUSerine/threonine-protein kinase pim-12.7.11.10.472
2yexYEXSerine/threonine-protein kinase Chk12.7.11.10.472
3vs7KS1Tyrosine-protein kinase HCK2.7.10.20.472
4ccbOFGALK tyrosine kinase receptor2.7.10.10.472
4fszHK8Serine/threonine-protein kinase Chk12.7.11.10.472
4jia1K3Tyrosine-protein kinase JAK2/0.472
2cgx3D3Serine/threonine-protein kinase Chk12.7.11.10.471
2ym6YM6Serine/threonine-protein kinase Chk12.7.11.10.471
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.471
3zlyYSODual specificity mitogen-activated protein kinase kinase 12.7.12.20.471
4brxKGWFocal adhesion kinase 12.7.10.20.471
1ny3ADPMAP kinase-activated protein kinase 22.7.11.10.470
3t3c017Gag-Pol polyprotein3.4.23.160.470
4ftu7HKSerine/threonine-protein kinase Chk12.7.11.10.470
4g2fC07Ephrin type-A receptor 32.7.10.10.470
4idtT28Mitogen-activated protein kinase kinase kinase 142.7.11.250.470
4loqSB4Mitogen-activated protein kinase 14/0.470
1aq1STUCyclin-dependent kinase 22.7.11.220.469
2hog710Serine/threonine-protein kinase Chk12.7.11.10.469
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.469
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.469
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.469
2wmxZY6Serine/threonine-protein kinase Chk12.7.11.10.469
3c4xATPRhodopsin kinase/0.469
3ufnROCGag-Pol polyprotein/0.469
4aa4QC0Mitogen-activated protein kinase 14/0.469
4aacAAVMitogen-activated protein kinase 14/0.469
4aw1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.469
4bibIEOMitogen-activated protein kinase kinase kinase 52.7.11.250.469
4gu610NFocal adhesion kinase 12.7.10.20.469
1oirHDYCyclin-dependent kinase 22.7.11.220.468
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.468
2pwlACPFibroblast growth factor receptor 2/0.468
2wmsZYSSerine/threonine-protein kinase Chk12.7.11.10.468
2xneASHAurora kinase A2.7.11.10.468
3eljGS7Mitogen-activated protein kinase 82.7.11.240.468
3r2b05BMAP kinase-activated protein kinase 22.7.11.10.468
3vf80JETyrosine-protein kinase SYK2.7.10.20.468
3w33W19Epidermal growth factor receptor2.7.10.10.468
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.468
4k8aK8AFocal adhesion kinase 12.7.10.20.468
4l7sG7KTyrosine-protein kinase ITK/TSK2.7.10.20.468
1unlRRCCyclin-dependent-like kinase 52.7.11.10.467
1uu3LY43-phosphoinositide-dependent protein kinase 12.7.11.10.467
2brnDF1Serine/threonine-protein kinase Chk12.7.11.10.467
2gdo12CSerine/threonine-protein kinase Chk12.7.11.10.467
2vwz7X6Ephrin type-B receptor 42.7.10.10.467
2x1nX1NCyclin-dependent kinase 22.7.11.220.467
2ycrHCWSerine/threonine-protein kinase Chk22.7.11.10.467
3a62STURibosomal protein S6 kinase beta-12.7.11.10.467
3efwAK8Aurora kinase A2.7.11.10.467
4ftkH9KSerine/threonine-protein kinase Chk12.7.11.10.467
4g1wG1WMitogen-activated protein kinase 82.7.11.240.467
4l9i8PRRhodopsin kinase/0.467
4mf129YTyrosine-protein kinase ITK/TSK2.7.10.20.467
2yirYIRSerine/threonine-protein kinase Chk22.7.11.10.466
3bgqVX2Serine/threonine-protein kinase pim-12.7.11.10.466
4cd0AWJALK tyrosine kinase receptor2.7.10.10.466
4qo9627Serine/threonine-protein kinase 242.7.11.10.466
2h8hH8HProto-oncogene tyrosine-protein kinase Src2.7.10.20.465
2o65MYFSerine/threonine-protein kinase pim-12.7.11.10.465
2p33J07Mitogen-activated protein kinase 102.7.11.240.465
2qhn582Serine/threonine-protein kinase Chk12.7.11.10.465
3ttjJBIMitogen-activated protein kinase 102.7.11.240.465
4a6cQG9Gag-Pol polyprotein3.4.23.160.465
4fg7ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.465
5aabVGHALK tyrosine kinase receptor2.7.10.10.465
2xikJ60Serine/threonine-protein kinase 252.7.11.10.464
2ym3YM3Serine/threonine-protein kinase Chk12.7.11.10.464
4enxZ20Serine/threonine-protein kinase pim-12.7.11.10.464
1i44ACPInsulin receptor2.7.10.10.463
2wmrZYRSerine/threonine-protein kinase Chk12.7.11.10.463
2ym5YM5Serine/threonine-protein kinase Chk12.7.11.10.463
3l8p0CEAngiopoietin-1 receptor2.7.10.10.463
2cgv3B3Serine/threonine-protein kinase Chk12.7.11.10.462
2itvANPEpidermal growth factor receptor2.7.10.10.462
2wmwZYWSerine/threonine-protein kinase Chk12.7.11.10.462
3hmm855TGF-beta receptor type-12.7.11.300.462
4erwSTUCyclin-dependent kinase 22.7.11.220.462
4ftiH7KSerine/threonine-protein kinase Chk12.7.11.10.462
4tuvCPZCytochrome P450 1191.140.462
5cvhADPCasein kinase II subunit alpha2.7.11.10.462
2itnANPEpidermal growth factor receptor2.7.10.10.461
3et7349Protein-tyrosine kinase 2-beta2.7.10.20.461
3tucFPWTyrosine-protein kinase SYK2.7.10.20.461
4f650S9Fibroblast growth factor receptor 1/0.461
4fg8ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.461
4fv8E63Mitogen-activated protein kinase 12.7.11.240.461
4hge15VTyrosine-protein kinase JAK2/0.461
4y95746Tyrosine-protein kinase/0.461
1py5PY1TGF-beta receptor type-12.7.11.300.460
2bkzSBCCyclin-dependent kinase 22.7.11.220.460
2ijmADPFocal adhesion kinase 12.7.10.20.460
2wxvWXVCyclin-dependent kinase 22.7.11.220.460
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.460
3tkh07SSerine/threonine-protein kinase Chk12.7.11.10.460
3uzp0CKCasein kinase I isoform delta2.7.11.10.460
4gh2HK0Serine/threonine-protein kinase Chk12.7.11.10.460
1bygSTUTyrosine-protein kinase CSK/0.459
2cgpCMPcAMP-activated global transcriptional regulator CRP/0.459
2ittAEEEpidermal growth factor receptor2.7.10.10.459
2ituITQEpidermal growth factor receptor2.7.10.10.459
2wmvZYVSerine/threonine-protein kinase Chk12.7.11.10.459
2xbjXBJSerine/threonine-protein kinase Chk22.7.11.10.459
2znq401Peroxisome proliferator-activated receptor delta/0.459
3qyw6PBMitogen-activated protein kinase 12.7.11.240.459
3v8t477Tyrosine-protein kinase ITK/TSK2.7.10.20.459
3vs5VSGTyrosine-protein kinase HCK2.7.10.20.459
3zh8C58Protein kinase C iota type2.7.11.130.459
4ckiADNProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.459
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.459
1c70L75Protease/0.458
1d4aFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.458
1y4lSVRBasic phospholipase A2 homolog 2/0.458
2acxANPG protein-coupled receptor kinase 62.7.11.160.458
2jkoBIJFocal adhesion kinase 12.7.10.20.458
4d58BI9Focal adhesion kinase 12.7.10.20.458
4gk3L87Ephrin type-A receptor 32.7.10.10.458
4oa9ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.458
2aquDR7Gag-Pol polyprotein3.4.23.160.457
2hxq373Serine/threonine-protein kinase Chk12.7.11.10.457
3aoxEMHALK tyrosine kinase receptor2.7.10.10.457
3vs2VSBTyrosine-protein kinase HCK2.7.10.20.457
3vs4VSFTyrosine-protein kinase HCK2.7.10.20.457
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.457
4i0t1B6Tyrosine-protein kinase SYK2.7.10.20.457
4yuqKS1Calmodulin-like domain protein kinase/0.457
5ax35IDMitogen-activated protein kinase 12.7.11.240.457
1nvtNAPShikimate dehydrogenase (NADP(+))/0.456
1nxkSTUMAP kinase-activated protein kinase 22.7.11.10.456
1qpdSTUTyrosine-protein kinase Lck2.7.10.20.456
1u4dDBQActivated CDC42 kinase 1/0.456
2pe24643-phosphoinositide-dependent protein kinase 12.7.11.10.456
2pk6O33V-1 protease/0.456
2r7b2533-phosphoinositide-dependent protein kinase 12.7.11.10.456
3hllI45Mitogen-activated protein kinase 14/0.456
4ansVGHALK tyrosine kinase receptor2.7.10.10.456
4bfmANPMaternal embryonic leucine zipper kinase2.7.11.10.456
4qmwKS1Serine/threonine-protein kinase 242.7.11.10.456
2gtk208Peroxisome proliferator-activated receptor gamma/0.455
2pvnP63Casein kinase II subunit alpha2.7.11.10.455
2vx07X7Ephrin type-B receptor 42.7.10.10.455
3h3cP1EProtein-tyrosine kinase 2-beta2.7.10.20.455
4aotGW8Serine/threonine-protein kinase 102.7.11.10.455
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.455
4g6oE28Mitogen-activated protein kinase 12.7.11.240.455
4l4eCAMCamphor 5-monooxygenase1.14.15.10.455
1h1wATP3-phosphoinositide-dependent protein kinase 12.7.11.10.454
1ke7LS3Cyclin-dependent kinase 22.7.11.220.454
1pjkANPCasein kinase II subunit alpha2.7.11.10.454
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.454
2e9oA58Serine/threonine-protein kinase Chk12.7.11.10.454
2h96893Mitogen-activated protein kinase 82.7.11.240.454
2nnpROCProtease/0.454
2oj9BMIInsulin-like growth factor 1 receptor2.7.10.10.454
2x8iX8ISerine/threonine-protein kinase Chk12.7.11.10.454
3bqr4RBDeath-associated protein kinase 3/0.454
3jxwLXGSerine/threonine-protein kinase pim-12.7.11.10.454
4gk2L66Ephrin type-A receptor 32.7.10.10.454
4i0s1B5Tyrosine-protein kinase SYK2.7.10.20.454
4qmxH8HSerine/threonine-protein kinase 242.7.11.10.454
1wvxBD4Death-associated protein kinase 12.7.11.10.453
2q5g1FAPeroxisome proliferator-activated receptor delta/0.453
2wipP49Cyclin-dependent kinase 22.7.11.220.453
2ym44YMSerine/threonine-protein kinase Chk12.7.11.10.453
3gggNADPrephenate dehydrogenase/0.453
3nynSGVG protein-coupled receptor kinase 62.7.11.160.453
3qcs3Q13-phosphoinositide-dependent protein kinase 12.7.11.10.453
3qlsNDPDihydrofolate reductase1.5.1.30.453
4c57FEFCyclin-G-associated kinase2.7.11.10.453
4im01FVSerine/threonine-protein kinase TBK12.7.11.10.453
4k181OBSerine/threonine-protein kinase pim-12.7.11.10.453
4l4fCAMCamphor 5-monooxygenase1.14.15.10.453
4yr9NADL-threonine 3-dehydrogenase, mitochondrial1.1.1.1030.453
1nvrSTUSerine/threonine-protein kinase Chk12.7.11.10.452
1okzUCN3-phosphoinositide-dependent protein kinase 12.7.11.10.452
1rw8580TGF-beta receptor type-12.7.11.300.452
2broDF2Serine/threonine-protein kinase Chk12.7.11.10.452
2hckQUETyrosine-protein kinase HCK2.7.10.20.452
2vwy7X5Ephrin type-B receptor 42.7.10.10.452
3cgfJNFMitogen-activated protein kinase 102.7.11.240.452
3cyxROCGag-Pol polyprotein3.4.23.160.452
3fwiCAMCamphor 5-monooxygenase1.14.15.10.452
3oxcROCProtease/0.452
4c02TAKActivin receptor type-12.7.11.300.452
4fsqHK3Serine/threonine-protein kinase Chk12.7.11.10.452
1ay0TPPTransketolase 12.2.1.10.451
1dr3HBIDihydrofolate reductase1.5.1.30.451
1h1s4SPCyclin-dependent kinase 22.7.11.220.451
1kboFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.451
1u54ACPActivated CDC42 kinase 1/0.451
1uu7BI23-phosphoinositide-dependent protein kinase 12.7.11.10.451
2hcdBIVVitamin D3 receptor A/0.451
2vx17X8Ephrin type-B receptor 42.7.10.10.451
2y6o1N1Ephrin type-A receptor 42.7.10.10.451
2ycsNXPSerine/threonine-protein kinase Chk22.7.11.10.451
3bhtMFRCyclin-dependent kinase 22.7.11.220.451
3kfn3TLGag-Pol polyprotein/0.451
4bdhWVISerine/threonine-protein kinase Chk22.7.11.10.451
4fsnA58Serine/threonine-protein kinase Chk12.7.11.10.451
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.451
4kbk1QGCasein kinase I isoform delta2.7.11.10.451
4mbl26LSerine/threonine-protein kinase pim-12.7.11.10.451
1eyqNARChalcone--flavonone isomerase 15.5.1.60.450
1fvv107Cyclin-dependent kinase 22.7.11.220.450
1yi3LY2Serine/threonine-protein kinase pim-12.7.11.10.450
2wedPP6Penicillopepsin-13.4.23.200.450
3c4eC4ESerine/threonine-protein kinase pim-12.7.11.10.450
3s85LK0Gag-Pol polyprotein/0.450
3vryB43Tyrosine-protein kinase HCK2.7.10.20.450
3w551FMMitogen-activated protein kinase 12.7.11.240.450
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.450
4fswHK6Serine/threonine-protein kinase Chk12.7.11.10.450
4ftq4HKSerine/threonine-protein kinase Chk12.7.11.10.450
5ar4SB2Receptor-interacting serine/threonine-protein kinase 22.7.11.10.450
1bwsNDPGDP-L-fucose synthase/0.449
1ckpPVBCyclin-dependent kinase 22.7.11.220.449
1m2pHNACasein kinase II subunit alpha2.7.11.10.449
1m2rMNYCasein kinase II subunit alpha2.7.11.10.449
1q41IXMGlycogen synthase kinase-3 beta2.7.11.260.449
1sh9RITGag-Pol polyprotein3.4.23.160.449
1snuSTUTyrosine-protein kinase ITK/TSK2.7.10.20.449
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.449
2br1PFPSerine/threonine-protein kinase Chk12.7.11.10.449
2cgu3A3Serine/threonine-protein kinase Chk12.7.11.10.449
2j0j4STFocal adhesion kinase 12.7.10.20.449
3hx4ANPCalmodulin-domain protein kinase 1/0.449
3kf7L9GMitogen-activated protein kinase 14/0.449
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.449
3zm422TDual specificity mitogen-activated protein kinase kinase 12.7.12.20.449
4aw0ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.449
4ftaH5KSerine/threonine-protein kinase Chk12.7.11.10.449
4gfg0XFTyrosine-protein kinase SYK2.7.10.20.449
4ia3BIVVitamin D3 receptor A/0.449
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.449
4xuhSFIPeroxisome proliferator-activated receptor gamma/0.449
1uv5BRWGlycogen synthase kinase-3 beta2.7.11.260.448
2q8sL92Peroxisome proliferator-activated receptor gamma/0.448
2uzdC85Cyclin-dependent kinase 22.7.11.220.448
2x8eX8ESerine/threonine-protein kinase Chk12.7.11.10.448
2ydjYDJSerine/threonine-protein kinase Chk12.7.11.10.448
3f5p741Insulin-like growth factor 1 receptor2.7.10.10.448
3gxlQIGTGF-beta receptor type-12.7.11.300.448
3hztJ60Calmodulin-like domain protein kinase isoform 3/0.448
3k5uPFQAurora kinase A2.7.11.10.448
3lpbNVBTyrosine-protein kinase JAK2/0.448
4fv4EK7Mitogen-activated protein kinase 12.7.11.240.448
4g160VMCasein kinase I isoform gamma-32.7.11.10.448
4hyh1AMSerine/threonine-protein kinase Chk12.7.11.10.448
4qgiROCGag-Pol polyprotein3.4.23.160.448
4wkqIREEpidermal growth factor receptor2.7.10.10.448
1rfuADPPyridoxal kinase2.7.1.350.447
2pe15173-phosphoinositide-dependent protein kinase 12.7.11.10.447
3fwjCAMCamphor 5-monooxygenase1.14.15.10.447
3jpv1DRSerine/threonine-protein kinase pim-12.7.11.10.447
3lqfNADGalactitol dehydrogenase/0.447
3rni21ZCyclin-dependent kinase 22.7.11.220.447
3sp6IL2Peroxisome proliferator-activated receptor alpha/0.447
3zmmF9JTyrosine-protein kinase JAK2/0.447
4a9tA9TSerine/threonine-protein kinase Chk22.7.11.10.447
4dfn0K1Tyrosine-protein kinase SYK2.7.10.20.447
4yzcSTUSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.447
1msmJE2Gag-Pol polyprotein3.4.23.160.446
1uvrBI83-phosphoinositide-dependent protein kinase 12.7.11.10.446
2e9v85ASerine/threonine-protein kinase Chk12.7.11.10.446
2q5p241Peroxisome proliferator-activated receptor gamma/0.446
2qhm7CSSerine/threonine-protein kinase Chk12.7.11.10.446
2ycfYCFSerine/threonine-protein kinase Chk22.7.11.10.446
2zv2609Calcium/calmodulin-dependent protein kinase kinase 22.7.11.170.446
3a60STURibosomal protein S6 kinase beta-12.7.11.10.446
3el4ROCGag-Pol polyprotein3.4.23.160.446
3f69XDRSerine/threonine-protein kinase PknB2.7.11.10.446
3gu83GUDeath-associated protein kinase 12.7.11.10.446
3kc3MK2MAP kinase-activated protein kinase 22.7.11.10.446
3zpsEQMGag-Pol polyprotein3.4.23.160.446
4a6bQG8Gag-Pol polyprotein3.4.23.160.446
4bdgP3JSerine/threonine-protein kinase Chk22.7.11.10.446
4dfrMTXDihydrofolate reductase1.5.1.30.446
4fv3EK6Mitogen-activated protein kinase 12.7.11.240.446
4gih0X5Non-receptor tyrosine-protein kinase TYK22.7.10.20.446
4k771Q4Tyrosine-protein kinase JAK1/0.446
4wboANWRhodopsin kinase/0.446
4zjuNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.446
1oecAA2Fibroblast growth factor receptor 2/0.445
2bdf24AProto-oncogene tyrosine-protein kinase Src2.7.10.20.445
2fxeDR7Gag-Pol polyprotein3.4.23.160.445
2g97DGBNicotinamide phosphoribosyltransferase2.4.2.120.445
2qhcAB1Protease/0.445
3cukFADD-amino-acid oxidase1.4.3.30.445
3ggfGVDSerine/threonine-protein kinase 26/0.445
3iaeD7KBenzaldehyde lyase/0.445
4b8lA0PAurora kinase B-A2.7.11.10.445
4btjADPTau-tubulin kinase 12.7.11.10.445
4fl2ANPTyrosine-protein kinase SYK2.7.10.20.445
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.10.445
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.445
4gj30XPNon-receptor tyrosine-protein kinase TYK22.7.10.20.445
4iwd1JCHepatocyte growth factor receptor2.7.10.10.445
4kl9NDPDihydrofolate reductase1.5.1.30.445
4r21STRCytochrome P450 family 17 polypeptide 2/0.445
1gqtACPRibokinase/0.444
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.444
2bpw1INGag-Pol polyprotein3.4.23.160.444
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.444
2objVRVSerine/threonine-protein kinase pim-12.7.11.10.444
2qd8065Gag-Pol polyprotein3.4.23.160.444
2wkz5AHGag-Pol polyprotein/0.444
2zdt46CMitogen-activated protein kinase 102.7.11.240.444
3a7hATPSerine/threonine-protein kinase 242.7.11.10.444
3kgaLX9MAP kinase-activated protein kinase 22.7.11.10.444
3kjrNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.444
3lxiCAMCytochrome P450/0.444
3nls016Gag-Pol polyprotein3.4.23.160.444
3zpuM8BGag-Pol polyprotein3.4.23.160.444
4e730NRMitogen-activated protein kinase 82.7.11.240.444
4erkOLOMitogen-activated protein kinase 12.7.11.240.444
4f081RSTyrosine-protein kinase JAK2/0.444
4hgs15GCasein kinase I isoform gamma-32.7.11.10.444
4kz01UJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
4l3j5FIRibosomal protein S6 kinase beta-12.7.11.10.444
4zlaBESCytosol aminopeptidase3.4.11.10.444
4zseANPEpidermal growth factor receptor2.7.10.10.444
6cp4CAMCamphor 5-monooxygenase1.14.15.10.444
1lsjNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.443
1nooCAHCamphor 5-monooxygenase1.14.15.10.443
1okySTU3-phosphoinositide-dependent protein kinase 12.7.11.10.443
2r0uM54Serine/threonine-protein kinase Chk12.7.11.10.443
2rkfAB1Pol protein/0.443
2znpK55Peroxisome proliferator-activated receptor delta/0.443
3a1nNADNDP-sugar epimerase/0.443
3nwxKVSGag-Pol polyprotein3.4.23.160.443
3qlrNDPDihydrofolate reductase1.5.1.30.443
3r83Z14Cyclin-dependent kinase 22.7.11.220.443
3ttiKBIMitogen-activated protein kinase 102.7.11.240.443
3vjoANPEpidermal growth factor receptor2.7.10.10.443
3vs3VSETyrosine-protein kinase HCK2.7.10.20.443
4a30QMIGlycylpeptide N-tetradecanoyltransferase/0.443
4fg9ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.443
4fuyEK2Mitogen-activated protein kinase 12.7.11.240.443
4lmuQUESerine/threonine-protein kinase pim-12.7.11.10.443
1h69FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.442
1hviA77Protease/0.442
2btrU73Cyclin-dependent kinase 22.7.11.220.442
2csnCKICasein kinase I homolog 12.7.11.10.442
2gs7ANPEpidermal growth factor receptor2.7.10.10.442
2qbmCAMCamphor 5-monooxygenase1.14.15.10.442
2vtpLZ9Cyclin-dependent kinase 22.7.11.220.442
2x4f16XMyosin light chain kinase family member 42.7.11.10.442
2yn8STUEphrin type-B receptor 42.7.10.10.442
3fln3FNMitogen-activated protein kinase 14/0.442
3i60E86Mitogen-activated protein kinase 12.7.11.240.442
3lxpIZANon-receptor tyrosine-protein kinase TYK22.7.10.20.442
3t113T1Gag-Pol polyprotein3.4.23.160.442
3t2kFADSulfide-quinone reductase/0.442
3triNAPPyrroline-5-carboxylate reductase/0.442
3uxyNADShort-chain dehydrogenase/reductase SDR/0.442
4bieIE6Mitogen-activated protein kinase kinase kinase 52.7.11.250.442
5cshATPCasein kinase II subunit alpha2.7.11.10.442
1fgc2NCGag-Pol polyprotein3.4.23.160.441
1hvsA77Gag-Pol polyprotein/0.441
1zeoC01Peroxisome proliferator-activated receptor gamma/0.441
2avvMK1Gag-Pol polyprotein3.4.23.160.441
2uzeC95Cyclin-dependent kinase 22.7.11.220.441
2xru400Aurora kinase A2.7.11.10.441
3l1sZ92Glycogen synthase kinase-3 beta2.7.11.260.441
3mpjFADGlutaryl-CoA dehydrogenase1.3.99.320.441
3nduROCGag-Pol polyprotein3.4.23.160.441
3sf6FDAGlutaryl-CoA dehydrogenase/0.441
3v9v21LPeroxisome proliferator-activated receptor gamma/0.441
3w2sW2REpidermal growth factor receptor2.7.10.10.441
3zewSTUEphrin type-B receptor 42.7.10.10.441
4a9rRU5Serine/threonine-protein kinase Chk22.7.11.10.441
4a9uA9USerine/threonine-protein kinase Chk22.7.11.10.441
4dh60KNBeta-secretase 13.4.23.460.441
4fl3ANPTyrosine-protein kinase SYK2.7.10.20.441
4ia1BIVVitamin D3 receptor A/0.441
4ivd15TTyrosine-protein kinase JAK1/0.441
1c1dNAIPhenylalanine dehydrogenase/0.440
1dirNADDihydropteridine reductase1.5.1.340.440
1hiiC20Gag-Pol polyprotein/0.440
1rekB8LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.440
1xwsBI1Serine/threonine-protein kinase pim-12.7.11.10.440
2a4fAAUV-1 protease/0.440
2excJNKMitogen-activated protein kinase 102.7.11.240.440
2hy0306Serine/threonine-protein kinase Chk12.7.11.10.440
2qboCAMCamphor 5-monooxygenase1.14.15.10.440
2qoqANPEphrin type-A receptor 32.7.10.10.440
2vwx7X4Ephrin type-B receptor 42.7.10.10.440
3d1xROCGag-Pol polyprotein3.4.23.160.440
3em4DR7Gag-Pol polyprotein3.4.23.160.440
3fzr3JZProtein-tyrosine kinase 2-beta2.7.10.20.440
3lltANPProtein serine/threonine kinase-1/0.440
4aa5NQBMitogen-activated protein kinase 14/0.440
4anv751Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
4ftm1HKSerine/threonine-protein kinase Chk12.7.11.10.440
4h8nNDPNADPH-dependent conjugated polyketone reductase C2/0.440
4ia7BIVVitamin D3 receptor A/0.440
4ix6ADPUncharacterized protein/0.440
4lb2DM5Serum albumin/0.440
4m87NADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.440
4yryNADGlutamate synthase, beta subunit/0.440