sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3m5e | JDR | Carbonic anhydrase 2 | 4.2.1.1 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3m5e | JDR | Carbonic anhydrase 2 | 4.2.1.1 | 1.000 | |
| 1g52 | F2B | Carbonic anhydrase 2 | 4.2.1.1 | 0.844 | |
| 2eu3 | FF3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.827 | |
| 4kap | 1QV | Carbonic anhydrase 2 | 4.2.1.1 | 0.821 | |
| 1g1d | FSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.790 | |
| 3eft | 3BS | Carbonic anhydrase 2 | 4.2.1.1 | 0.786 | |
| 1if6 | FBU | Carbonic anhydrase 2 | 4.2.1.1 | 0.785 | |
| 1kwq | SG1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.781 | |
| 1kwr | SG2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.779 | |
| 1bn4 | AL9 | Carbonic anhydrase 2 | 4.2.1.1 | 0.777 | |
| 1if7 | SBR | Carbonic anhydrase 2 | 4.2.1.1 | 0.773 | |
| 4m2r | BZ1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.770 | |
| 2h15 | B19 | Carbonic anhydrase 2 | 4.2.1.1 | 0.766 | |
| 3m2n | J74 | Carbonic anhydrase 2 | 4.2.1.1 | 0.763 | |
| 3daz | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.759 | |
| 3qyk | IE2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.758 | |
| 3b4f | TUO | Carbonic anhydrase 2 | 4.2.1.1 | 0.754 | |
| 3dc3 | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.751 | |
| 1okl | MNS | Carbonic anhydrase 2 | 4.2.1.1 | 0.745 | |
| 2weh | FB1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.744 | |
| 1a42 | BZU | Carbonic anhydrase 2 | 4.2.1.1 | 0.740 | |
| 1g4o | BSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.738 | |
| 1zsb | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.738 | |
| 3k2f | NKX | Carbonic anhydrase 2 | 4.2.1.1 | 0.730 | |
| 4iwz | 1GO | Carbonic anhydrase 2 | 4.2.1.1 | 0.730 | |
| 1g45 | FSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.727 | |
| 3m98 | E02 | Carbonic anhydrase 2 | 4.2.1.1 | 0.727 | |
| 3m2y | BE0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.717 | |
| 1bnt | AL2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.716 | |
| 2h4n | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.714 | |
| 4m2v | BZ1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.713 | |
| 3f4x | KLT | Carbonic anhydrase 2 | 4.2.1.1 | 0.711 | |
| 4itp | 1GD | Carbonic anhydrase 2 | 4.2.1.1 | 0.708 | |
| 1bnw | TPD | Carbonic anhydrase 2 | 4.2.1.1 | 0.706 | |
| 3ffp | LC1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.706 | |
| 3mho | J43 | Carbonic anhydrase 2 | 4.2.1.1 | 0.705 | |
| 3dcs | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.703 | |
| 1bnn | AL1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.702 | |
| 3d9z | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.702 | |
| 3sbh | E65 | Carbonic anhydrase 2 | 4.2.1.1 | 0.702 | |
| 1g4j | FFB | Carbonic anhydrase 2 | 4.2.1.1 | 0.701 | |
| 4bf1 | 9FK | Carbonic anhydrase 2 | 4.2.1.1 | 0.697 | |
| 4kni | E1E | Carbonic anhydrase 2 | 4.2.1.1 | 0.697 | |
| 1bn1 | AL5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.696 | |
| 3dcc | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.691 | |
| 1i9n | IOA | Carbonic anhydrase 2 | 4.2.1.1 | 0.690 | |
| 4k13 | ETS | Carbonic anhydrase 2 | 4.2.1.1 | 0.689 | |
| 1cil | ETS | Carbonic anhydrase 2 | 4.2.1.1 | 0.687 | |
| 3kig | DA4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.687 | |
| 1i9m | INW | Carbonic anhydrase 2 | 4.2.1.1 | 0.685 | |
| 2wej | FB2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.680 | |
| 4n16 | CHD | Carbonic anhydrase 2 | 4.2.1.1 | 0.680 | |
| 3mhc | ARZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.676 | |
| 4ito | MPX | Carbonic anhydrase 2 | 4.2.1.1 | 0.676 | |
| 1if4 | FBS | Carbonic anhydrase 2 | 4.2.1.1 | 0.674 | |
| 1bnm | AL8 | Carbonic anhydrase 2 | 4.2.1.1 | 0.671 | |
| 4mo8 | 2VQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.671 | |
| 4bf6 | X0Q | Carbonic anhydrase 2 | 4.2.1.1 | 0.670 | |
| 1i91 | INQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.668 | |
| 3igp | DT7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.668 | |
| 3hku | TOR | Carbonic anhydrase 2 | 4.2.1.1 | 0.666 | |
| 5flt | VJJ | Carbonic anhydrase 2 | 4.2.1.1 | 0.666 | |
| 3dcw | EZL | Carbonic anhydrase 2 | 4.2.1.1 | 0.663 | |
| 3m67 | E36 | Carbonic anhydrase 2 | 4.2.1.1 | 0.660 | |
| 3oik | WZB | Carbonic anhydrase 2 | 4.2.1.1 | 0.658 | |
| 4k0t | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.657 | |
| 3dbu | D8W | Carbonic anhydrase 2 | 4.2.1.1 | 0.655 | |
| 1bnq | AL4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.653 | |
| 1bnv | AL7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.653 | |
| 1bnu | AL3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.651 | |
| 3s8x | E59 | Carbonic anhydrase 2 | 4.2.1.1 | 0.651 | |
| 3myq | E27 | Carbonic anhydrase 2 | 4.2.1.1 | 0.649 | |
| 3sbi | E90 | Carbonic anhydrase 2 | 4.2.1.1 | 0.649 | |
| 1ttm | 667 | Carbonic anhydrase 2 | 4.2.1.1 | 0.646 | |
| 3sax | E50 | Carbonic anhydrase 2 | 4.2.1.1 | 0.643 | |
| 3mna | DWH | Carbonic anhydrase 2 | 4.2.1.1 | 0.642 | |
| 3n0n | P9B | Carbonic anhydrase 2 | 4.2.1.1 | 0.640 | |
| 3s9t | E49 | Carbonic anhydrase 2 | 4.2.1.1 | 0.640 | |
| 3v2j | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.635 | |
| 3oy0 | OY0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.632 | |
| 1okn | STB | Carbonic anhydrase 2 | 4.2.1.1 | 0.631 | |
| 3mhi | J90 | Carbonic anhydrase 2 | 4.2.1.1 | 0.631 | |
| 3oys | OYS | Carbonic anhydrase 2 | 4.2.1.1 | 0.630 | |
| 3po6 | DT9 | Carbonic anhydrase 2 | 4.2.1.1 | 0.630 | |
| 4ilx | 1EZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.629 | |
| 3mhl | J71 | Carbonic anhydrase 2 | 4.2.1.1 | 0.628 | |
| 1i8z | INL | Carbonic anhydrase 2 | 4.2.1.1 | 0.626 | |
| 3m40 | J45 | Carbonic anhydrase 2 | 4.2.1.1 | 0.626 | |
| 3n2p | AYX | Carbonic anhydrase 2 | 4.2.1.1 | 0.626 | |
| 3bl1 | BL1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.625 | |
| 3rz8 | RZ8 | Carbonic anhydrase 2 | 4.2.1.1 | 0.625 | |
| 1okm | SAB | Carbonic anhydrase 2 | 4.2.1.1 | 0.622 | |
| 3d8w | D8W | Carbonic anhydrase 2 | 4.2.1.1 | 0.620 | |
| 3dd8 | 2C7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.620 | |
| 2x7t | WZB | Carbonic anhydrase 2 | 4.2.1.1 | 0.619 | |
| 3mmf | D9H | Carbonic anhydrase 2 | 4.2.1.1 | 0.617 | |
| 1i90 | INM | Carbonic anhydrase 2 | 4.2.1.1 | 0.616 | |
| 1eou | SMS | Carbonic anhydrase 2 | 4.2.1.1 | 0.614 | |
| 4knj | E1F | Carbonic anhydrase 2 | 4.2.1.1 | 0.614 | |
| 1cny | EG3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.613 | |
| 3m96 | E38 | Carbonic anhydrase 2 | 4.2.1.1 | 0.613 | |
| 3l14 | I7B | Carbonic anhydrase 2 | 4.2.1.1 | 0.611 | |
| 1bn3 | AL6 | Carbonic anhydrase 2 | 4.2.1.1 | 0.609 | |
| 3ni5 | C1H | Carbonic anhydrase 2 | 4.2.1.1 | 0.609 | |
| 1oq5 | CEL | Carbonic anhydrase 2 | 4.2.1.1 | 0.608 | |
| 1if8 | SBS | Carbonic anhydrase 2 | 4.2.1.1 | 0.606 | |
| 3oyq | OYQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.606 | |
| 1xpz | 4TZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.603 | |
| 2wd2 | MS5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.600 | |
| 3oim | VZ5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.600 | |
| 3ml2 | SU0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.599 | |
| 3n3j | WWV | Carbonic anhydrase 2 | 4.2.1.1 | 0.597 | |
| 1g54 | FFB | Carbonic anhydrase 2 | 4.2.1.1 | 0.595 | |
| 4pxx | CHD | Carbonic anhydrase 2 | 4.2.1.1 | 0.592 | |
| 3bet | CTF | Carbonic anhydrase 2 | 4.2.1.1 | 0.591 | |
| 3nb5 | R21 | Carbonic anhydrase 2 | 4.2.1.1 | 0.591 | |
| 1if5 | FBT | Carbonic anhydrase 2 | 4.2.1.1 | 0.589 | |
| 2weg | FBV | Carbonic anhydrase 2 | 4.2.1.1 | 0.589 | |
| 2weo | FBW | Carbonic anhydrase 2 | 4.2.1.1 | 0.589 | |
| 3p5l | IT5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.587 | |
| 4dz7 | D02 | Carbonic anhydrase 2 | 4.2.1.1 | 0.587 | |
| 3n4b | WWZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.586 | |
| 1cnw | EG1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.585 | |
| 3mdz | EZL | Carbonic anhydrase 7 | 4.2.1.1 | 0.585 | |
| 3mzc | S6I | Carbonic anhydrase 2 | 4.2.1.1 | 0.581 | |
| 3t84 | SG6 | Carbonic anhydrase 2 | 4.2.1.1 | 0.581 | |
| 1i9p | IOE | Carbonic anhydrase 2 | 4.2.1.1 | 0.576 | |
| 1yda | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.576 | |
| 1cnx | EG2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.571 | |
| 1jd0 | AZM | Carbonic anhydrase 12 | 4.2.1.1 | 0.569 | |
| 2x7u | WZA | Carbonic anhydrase 2 | 4.2.1.1 | 0.569 | |
| 3f7u | AG4 | Carbonic anhydrase 4 | 4.2.1.1 | 0.569 | |
| 1xq0 | 4TR | Carbonic anhydrase 2 | 4.2.1.1 | 0.566 | |
| 2q1q | OSP | Carbonic anhydrase 2 | 4.2.1.1 | 0.563 | |
| 4ht2 | V50 | Carbonic anhydrase 12 | 4.2.1.1 | 0.554 | |
| 4kp8 | E1G | Carbonic anhydrase 12 | 4.2.1.1 | 0.552 | |
| 3t85 | SG7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.548 | |
| 4lu3 | AZM | Carbonic anhydrase 14 | 4.2.1.1 | 0.546 | |
| 3znc | BZ1 | Carbonic anhydrase 4 | 4.2.1.1 | 0.544 | |
| 2pow | I7C | Carbonic anhydrase 2 | 4.2.1.1 | 0.541 | |
| 4uov | AZM | Carbonate dehydratase | / | 0.537 | |
| 3f7b | AG5 | Carbonic anhydrase 4 | 4.2.1.1 | 0.535 | |
| 4kp5 | E1F | Carbonic anhydrase 12 | 4.2.1.1 | 0.532 | |
| 3fw3 | ETS | Carbonic anhydrase 4 | 4.2.1.1 | 0.531 | |
| 4k0z | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.529 | |
| 4x5s | AZM | Carbonic anhydrase (Carbonate dehydratase) | / | 0.528 | |
| 3t82 | SG4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.526 | |
| 3dd0 | EZL | Carbonic anhydrase 2 | 4.2.1.1 | 0.522 | |
| 1rj6 | AZM | Carbonic anhydrase 14 | 4.2.1.1 | 0.518 | |
| 1vi2 | NAD | Quinate/shikimate dehydrogenase | / | 0.508 | |
| 1i9q | IOF | Carbonic anhydrase 2 | 4.2.1.1 | 0.507 | |
| 4jqh | 1MF | Alr2278 protein | / | 0.503 | |
| 4knm | E1E | Carbonic anhydrase 13 | 4.2.1.1 | 0.501 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.497 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.496 | |
| 3p74 | FMN | Pentaerythritol tetranitrate reductase | / | 0.495 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.493 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.493 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.491 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.490 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.489 | |
| 3jyp | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.489 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.487 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.487 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.486 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.486 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.486 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.485 | |
| 3p8i | FMN | Pentaerythritol tetranitrate reductase | / | 0.485 | |
| 2iyf | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.482 | |
| 3zbs | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.481 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.481 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.480 | |
| 4xrb | NDP | Possible bifunctional enzyme riboflavin biosynthesis protein RibD: diaminohydroxyphosphoribosylaminopyrimidine deaminase (Riboflavin-specific deaminase) + 5-amino-6-(5-phosphoribosylamino)uracil reduc | / | 0.480 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.479 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.479 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.478 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.478 | |
| 1c7o | PPG | Hemolysin | / | 0.477 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.476 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.475 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.475 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.475 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.474 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.474 | |
| 1dmy | AZM | Carbonic anhydrase 5A, mitochondrial | 4.2.1.1 | 0.473 | |
| 1gpd | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.473 | |
| 1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.473 | |
| 3fp0 | FP0 | 15-O-acetyltransferase | / | 0.473 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.473 | |
| 1w19 | T5P | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.472 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.472 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.472 | |
| 1foa | UD1 | Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase | 2.4.1.101 | 0.471 | |
| 1qoq | IGP | Tryptophan synthase alpha chain | / | 0.471 | |
| 3apw | DP0 | Alpha-1-acid glycoprotein 2 | / | 0.471 | |
| 3b6p | TMP | Three-prime repair exonuclease 1 | 3.1.11.2 | 0.471 | |
| 1nvt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.470 | |
| 1rx0 | FAD | Isobutyryl-CoA dehydrogenase, mitochondrial | 1.3.99 | 0.470 | |
| 3gfb | NAD | L-threonine 3-dehydrogenase | / | 0.470 | |
| 4oqy | NDP | (S)-imine reductase | / | 0.470 | |
| 4rel | KMP | Glycosyltransferase | / | 0.470 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.469 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.469 | |
| 1m13 | HYF | Nuclear receptor subfamily 1 group I member 2 | / | 0.467 | |
| 2q7o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.467 | |
| 1akb | PPD | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.466 | |
| 1npd | NAD | Quinate/shikimate dehydrogenase | / | 0.466 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.466 | |
| 2wns | OMP | Uridine 5'-monophosphate synthase | 2.4.2.10 | 0.466 | |
| 3k8q | 22A | Purine nucleoside phosphorylase | 2.4.2.1 | 0.466 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.466 | |
| 4j49 | 1J1 | Uncharacterized protein | / | 0.466 | |
| 1qrp | HH0 | Pepsin A-4 | 3.4.23.1 | 0.465 | |
| 2zvc | SAH | Precorrin-3 C17-methyltransferase | / | 0.465 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.465 | |
| 3t4e | NAD | Quinate/shikimate dehydrogenase | / | 0.465 | |
| 4iae | 1DX | Alr2278 protein | / | 0.465 | |
| 4iah | 1DX | Alr2278 protein | / | 0.465 | |
| 4j3m | AJ8 | Tankyrase-2 | 2.4.2.30 | 0.465 | |
| 1xva | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.464 | |
| 3jyq | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.464 | |
| 3m2v | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.464 | |
| 3vyf | VYF | Renin | 3.4.23.15 | 0.464 | |
| 1q51 | CAA | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.463 | |
| 2i65 | NAD | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.463 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.463 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.463 | |
| 4a87 | NAR | Major pollen allergen Bet v 1-A | / | 0.463 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.463 | |
| 1x1d | SAH | C-20 methyltransferase | / | 0.462 | |
| 3p67 | FMN | Pentaerythritol tetranitrate reductase | / | 0.462 | |
| 4bri | UNP | Ectonucleoside triphosphate diphosphohydrolase I | / | 0.462 | |
| 1lc3 | NAD | Biliverdin reductase A | 1.3.1.24 | 0.461 | |
| 1ps9 | MDE | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.461 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.461 | |
| 3aos | JH2 | Hemolymph juvenile hormone binding protein | / | 0.461 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.461 | |
| 4ycp | FMN | tRNA-dihydrouridine(16) synthase | / | 0.461 | |
| 2f99 | AKV | Aklanonic acid methyl ester cyclase AcmA | 5.5.1.23 | 0.460 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.460 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.460 | |
| 3aez | GDP | Pantothenate kinase | 2.7.1.33 | 0.460 | |
| 3img | BZ3 | Pantothenate synthetase | 6.3.2.1 | 0.460 | |
| 3mkn | DNB | Pyrimidine-specific ribonucleoside hydrolase RihB | / | 0.460 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.460 | |
| 7std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.460 | |
| 1ivs | VAA | Valine--tRNA ligase | 6.1.1.9 | 0.459 | |
| 1tll | FMN | Nitric oxide synthase, brain | 1.14.13.39 | 0.459 | |
| 1vbi | NAD | Malate/L-lactate dehydrogenase family protein | / | 0.459 | |
| 2a92 | NAI | L-lactate dehydrogenase | / | 0.459 | |
| 4y1b | NAP | AntE | / | 0.459 | |
| 1fml | RTL | Retinol dehydratase | / | 0.458 | |
| 1kbi | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.458 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.458 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.458 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.458 | |
| 3ryk | TYD | dTDP-4-dehydrorhamnose 3,5-epimerase | / | 0.458 | |
| 4a86 | H35 | Major pollen allergen Bet v 1-A | / | 0.458 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.458 | |
| 4kby | C2E | Stimulator of interferon genes protein | / | 0.458 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.457 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.457 | |
| 3b4y | F42 | F420-dependent glucose-6-phosphate dehydrogenase | / | 0.457 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.457 | |
| 3rsv | 3RS | Beta-secretase 1 | 3.4.23.46 | 0.457 | |
| 1rzu | ADP | Glycogen synthase 1 | 2.4.1.21 | 0.456 | |
| 1t9g | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.456 | |
| 1w34 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.456 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.456 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.456 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.456 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.456 | |
| 3m1v | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.456 | |
| 3m1v | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.456 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.456 | |
| 4c49 | HCY | Corticosteroid-binding globulin | / | 0.456 | |
| 5cho | FAD | Flavin reductase | / | 0.456 | |
| 2j9l | ATP | H(+)/Cl(-) exchange transporter 5 | / | 0.455 | |
| 3c1o | NAP | Eugenol synthase | / | 0.455 | |
| 3g70 | A5T | Renin | 3.4.23.15 | 0.455 | |
| 4a30 | QMI | Glycylpeptide N-tetradecanoyltransferase | / | 0.455 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.455 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.455 | |
| 4ms1 | 381 | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.455 | |
| 4nvk | 2NY | Peroxidase | / | 0.455 | |
| 4w5k | PLP | Aspartate aminotransferase, mitochondrial | / | 0.455 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.454 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.454 | |
| 1p0p | BCH | Cholinesterase | 3.1.1.8 | 0.454 | |
| 1rft | PXM | Pyridoxal kinase | 2.7.1.35 | 0.454 | |
| 1x1a | SAM | C-20 methyltransferase | / | 0.454 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.454 | |
| 3af1 | GDP | Pantothenate kinase | 2.7.1.33 | 0.454 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.454 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.454 | |
| 4drj | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.454 | |
| 4drj | RAP | Peptidyl-prolyl cis-trans isomerase FKBP4 | 5.2.1.8 | 0.454 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.454 | |
| 4x7u | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.454 | |
| 2b4r | AES | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.453 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.453 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.453 | |
| 2g5w | 8PG | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.453 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.453 | |
| 2v16 | C47 | Renin | 3.4.23.15 | 0.453 | |
| 3jyo | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.453 | |
| 3vyd | VYD | Renin | 3.4.23.15 | 0.453 | |
| 4eph | 0RK | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.453 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.453 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.453 | |
| 5e5h | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.453 | |
| 6std | MS2 | Scytalone dehydratase | 4.2.1.94 | 0.453 | |
| 1kp2 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.452 | |
| 1wze | NAD | Malate dehydrogenase | / | 0.452 | |
| 2a59 | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.452 | |
| 2vn1 | FK5 | Peptidylprolyl isomerase | / | 0.452 | |
| 2y8l | ADP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.452 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.452 | |
| 3e34 | ED1 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.452 | |
| 3e34 | ED1 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.452 | |
| 3l6j | Z90 | Alr2278 protein | / | 0.452 | |
| 3lxe | TOR | Carbonic anhydrase 1 | 4.2.1.1 | 0.452 | |
| 3uxv | GUN | NADPH-dependent 7-cyano-7-deazaguanine reductase | / | 0.452 | |
| 4hmz | 18T | dTDP-4-dehydro-6-deoxyglucose 3-epimerase | 5.1.3.27 | 0.452 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.452 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.451 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1r6u | TYM | Tryptophan--tRNA ligase, cytoplasmic | 6.1.1.2 | 0.451 | |
| 2bjf | DXC | Choloylglycine hydrolase | 3.5.1.24 | 0.451 | |
| 2wqp | WQP | Polysialic acid capsule biosynthesis protein SiaC | / | 0.451 | |
| 3tr0 | 5GP | Guanylate kinase | / | 0.451 | |
| 4eyw | L0R | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.451 | |
| 4mr7 | 2BV | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.451 | |
| 4r81 | FMN | Predicted NADH dehydrogenase | / | 0.451 | |
| 4zla | BES | Cytosol aminopeptidase | 3.4.11.1 | 0.451 | |
| 5er0 | FAD | Uncharacterized NAD(FAD)-dependent dehydrogenase | / | 0.451 | |
| 5fl4 | 9FK | Carbonic anhydrase 9 | 4.2.1.1 | 0.451 | |
| 1kt8 | ILP | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.450 | |
| 1tqf | 32P | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 2fr0 | NDP | 6-deoxyerythronolide-B synthase EryA1, modules 1 and 2 | / | 0.450 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.450 | |
| 2j09 | FMN | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.450 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.450 | |
| 2qo5 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.450 | |
| 2yj4 | ATP | Copper-transporting ATPase | / | 0.450 | |
| 2zs8 | ADP | Pantothenate kinase | 2.7.1.33 | 0.450 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.450 | |
| 3lqs | PSZ | D-alanine aminotransferase | 2.6.1.21 | 0.450 | |
| 3qsa | TA7 | Anthranilate phosphoribosyltransferase | / | 0.450 | |
| 4oe4 | NAD | Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial | 1.2.1.88 | 0.450 | |
| 1bdm | NAX | Malate dehydrogenase | / | 0.449 | |
| 1egd | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.449 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.449 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.449 | |
| 2a58 | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.449 | |
| 2g26 | 3LG | Renin | 3.4.23.15 | 0.449 | |
| 2idk | C2F | Glycine N-methyltransferase | 2.1.1.20 | 0.449 | |
| 2pau | D5M | 5'-deoxynucleotidase YfbR | / | 0.449 | |
| 2wvl | GDD | Mannosyl-3-phosphogylcerate synthase | / | 0.449 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.449 | |
| 3dg8 | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.449 | |
| 3e8x | NAP | BH1520 protein | / | 0.449 | |
| 3rpe | FAD | Putative modulator of drug activity | / | 0.449 | |
| 4boe | CLR | Japanin | / | 0.449 | |
| 4cjx | 9L9 | C-1-tetrahydrofolate synthase, cytoplasmic, putative | / | 0.449 | |
| 4yco | FMN | tRNA-dihydrouridine(16) synthase | / | 0.449 | |
| 1jf2 | CZH | Obelin | / | 0.448 | |
| 1mja | COA | Histone acetyltransferase ESA1 | / | 0.448 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.448 | |
| 2a0y | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.448 | |
| 2c12 | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.448 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.448 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial | 1.2.4.4 | 0.448 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial | 1.2.4.4 | 0.448 | |
| 2wu4 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 2y1t | DUD | SPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS | 3.6.1.23 | 0.448 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.448 | |
| 3i0p | NAD | Malate dehydrogenase, putative | / | 0.448 | |
| 3img | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.448 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
| 3s3v | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 3ziu | LSS | Leucyl-tRNA synthetase | / | 0.448 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.448 | |
| 4euf | NAD | Trans-2-enoyl-CoA reductase [NADH] | / | 0.448 | |
| 1diu | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1uxj | NAD | Malate dehydrogenase | / | 0.447 | |
| 2abj | CBC | Branched-chain-amino-acid aminotransferase, cytosolic | 2.6.1.42 | 0.447 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.447 | |
| 2xui | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.447 | |
| 2yoz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.447 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 3bxo | UPP | dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose | / | 0.447 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 4dan | 2FA | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.447 | |
| 4p9d | TMP | Deoxycytidylate deaminase | / | 0.447 | |
| 1a72 | PAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.446 | |
| 1psa | 0ZL | Pepsin A | 3.4.23.1 | 0.446 | |
| 1yqs | BSA | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.446 | |
| 2a9y | 26A | Adenosine kinase | 2.7.1.20 | 0.446 | |
| 3b2s | B2S | Trichothecene 3-O-acetyltransferase | / | 0.446 | |
| 3rba | COD | Phosphopantetheine adenylyltransferase | / | 0.446 | |
| 4dbc | 3QP | Aspartate aminotransferase | 2.6.1.1 | 0.446 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 4fxy | 0W2 | Neurolysin, mitochondrial | 3.4.24.16 | 0.446 | |
| 4uwm | FMN | 3,6-diketocamphane 1,6 monooxygenase | 1.14.13 | 0.446 | |
| 5fsi | 8DG | 7,8-dihydro-8-oxoguanine triphosphatase | 3.6.1.55 | 0.446 | |
| 1gax | VAA | Valine--tRNA ligase | 6.1.1.9 | 0.445 | |
| 1szg | FNS | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.445 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.445 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.445 | |
| 2bri | ANP | Uridylate kinase | 2.7.4.22 | 0.445 | |
| 2e0n | SAH | Precorrin-2 C20-methyltransferase | / | 0.445 | |
| 2g1o | 2IG | Renin | 3.4.23.15 | 0.445 | |
| 2hk9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.445 | |
| 2hs6 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.445 | |
| 2npx | NAD | NADH peroxidase | 1.11.1.1 | 0.445 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.445 | |
| 2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.445 | |
| 2zsa | ADP | Pantothenate kinase | 2.7.1.33 | 0.445 | |
| 3tqx | PLP | 2-amino-3-ketobutyrate coenzyme A ligase | / | 0.445 | |
| 4djw | 0KP | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 4ijr | NDP | D-arabinose dehydrogenase [NAD(P)+] heavy chain | 1.1.1.117 | 0.445 | |
| 4n1g | CEI | Obelin | / | 0.445 | |
| 4pgh | SAM | Caffeic acid O-methyltransferase | / | 0.445 | |
| 4rls | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.445 | |
| 4x7v | MIV | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.445 | |
| 4yp6 | NAP | Nicotinamide-nucleotide adenylyltransferase | 2.7.7.1 | 0.445 | |
| 4zj8 | SUV | Orexin receptor type 1 | / | 0.445 | |
| 1iay | AVG | 1-aminocyclopropane-1-carboxylate synthase 2 | 4.4.1.14 | 0.444 | |
| 1l2t | ATP | Uncharacterized ABC transporter ATP-binding protein MJ0796 | / | 0.444 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.444 | |
| 2a0w | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.444 | |
| 2geu | COK | Pantothenate kinase | 2.7.1.33 | 0.444 | |
| 2i4p | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.444 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.444 | |
| 2oaz | I96 | Methionine aminopeptidase 2 | / | 0.444 | |
| 2xvi | FAD | Putative flavin-containing monooxygenase | / | 0.444 | |
| 3b1d | PLS | BetaC-S lyase | / | 0.444 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 3eks | CY9 | Actin-5C | / | 0.444 | |
| 3flk | NAI | Tartrate dehydrogenase/decarboxylase | 1.1.1.93 | 0.444 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.444 | |
| 3own | 3OX | Renin | 3.4.23.15 | 0.444 | |
| 3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.444 | |
| 4bv9 | NDP | Ketimine reductase mu-crystallin | 1.5.1.25 | 0.444 | |
| 4eag | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.444 | |
| 4ey7 | E20 | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 4gz6 | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.444 | |
| 4rvg | TYD | D-mycarose 3-C-methyltransferase | / | 0.444 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.444 | |
| 3uon | QNB | Muscarinic acetylcholine receptor M2 | / | 0.444 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.443 | |
| 1dig | L37 | C-1-tetrahydrofolate synthase, cytoplasmic | 1.5.1.5 | 0.443 | |
| 1mjb | ACO | Histone acetyltransferase ESA1 | / | 0.443 | |
| 1mxf | MTX | Putative pteridine reductase 2 | / | 0.443 | |
| 1w6r | GNT | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 2g1y | 5IG | Renin | 3.4.23.15 | 0.443 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.443 | |
| 3a0t | ADP | Sensor histidine kinase | / | 0.443 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.443 | |
| 3gnc | QQQ | Glutaryl-CoA dehydrogenase | / | 0.443 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.443 | |
| 3mpj | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.443 | |
| 3tqc | ADP | Pantothenate kinase | / | 0.443 | |
| 4cuk | NAI | D-lactate dehydrogenase | / | 0.443 | |
| 4h3g | 10Q | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 4xmx | BES | Aminopeptidase N | 3.4.11.2 | 0.443 | |
| 1ahg | TYR_PLP | Aspartate aminotransferase | 2.6.1.1 | 0.442 | |
| 1mj9 | COA | Histone acetyltransferase ESA1 | / | 0.442 | |
| 1pz0 | NAP | Protein IolS | 1.1.1 | 0.442 | |
| 2a57 | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.442 | |
| 2c20 | NAD | UDP-glucose 4-epimerase | / | 0.442 | |
| 2e9a | B28 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.442 | |
| 2fk8 | SAM | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.442 | |
| 2std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.442 | |
| 2v5a | LZL | Biotin carboxylase | 6.3.4.14 | 0.442 | |
| 2w6p | OA4 | Biotin carboxylase | 6.3.4.14 | 0.442 | |
| 3duf | R1T | Pyruvate dehydrogenase E1 component subunit alpha | 1.2.4.1 | 0.442 | |
| 3duf | R1T | Pyruvate dehydrogenase E1 component subunit beta | 1.2.4.1 | 0.442 | |
| 3g1r | FIT | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.442 | |
| 3pfd | FDA | Acyl-CoA dehydrogenase FadE25 | / | 0.442 | |
| 4b4w | 9L9 | Bifunctional protein FolD | / | 0.442 | |
| 4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.442 | |
| 4i1n | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 4wdb | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.442 | |
| 5eio | NAP | [LysW]-L-2-aminoadipate 6-phosphate reductase | / | 0.442 | |
| 1aka | PLP | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.441 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.441 | |
| 1gtr | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.441 | |
| 1k4m | NAD | Nicotinate-nucleotide adenylyltransferase | 2.7.7.18 | 0.441 | |
| 1pfy | MSP | Methionine--tRNA ligase | 6.1.1.10 | 0.441 | |
| 1rsz | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.441 | |
| 1rt9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.441 | |
| 1zxm | ANP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.441 | |
| 2ea4 | F79 | Methionine aminopeptidase 2 | / | 0.441 | |
| 2eud | GCQ | Ribonucleoside-diphosphate reductase large chain 1 | 1.17.4.1 | 0.441 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.441 | |
| 3o03 | NAP | Dehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase) | / | 0.441 | |
| 3oad | LPO | Renin | 3.4.23.15 | 0.441 | |
| 3to3 | ATP | Petrobactin biosynthesis protein AsbB | / | 0.441 | |
| 3wag | TYD | Glycosyltransferase | / | 0.441 | |
| 3zs7 | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.441 | |
| 4e2y | JHZ | Methyltransferase | / | 0.441 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.441 | |
| 4rp8 | ASC | Ascorbate-specific PTS system EIIC component | / | 0.441 | |
| 1bil | 0IU | Renin | 3.4.23.15 | 0.440 | |
| 1q0r | AKT | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.440 | |
| 1q84 | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 1uhh | CZP | Aequorin-2 | / | 0.440 | |
| 1uma | IN2 | Prothrombin | 3.4.21.5 | 0.440 | |
| 1ygj | RMC | Pyridoxal kinase | 2.7.1.35 | 0.440 | |
| 2fxu | BID | Actin, alpha skeletal muscle | / | 0.440 | |
| 2vyq | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.440 | |
| 2w6c | BM4 | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 2x06 | NAD | L-sulfolactate dehydrogenase | / | 0.440 | |
| 2x0i | NAI | Malate dehydrogenase | / | 0.440 | |
| 3af0 | GDP | Pantothenate kinase | 2.7.1.33 | 0.440 | |
| 3c1k | T15 | Prothrombin | 3.4.21.5 | 0.440 | |
| 3ckq | UPG | Glucosyl-3-phosphoglycerate synthase | 2.4.1.266 | 0.440 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 3ibq | ATP | Pyridoxal kinase | / | 0.440 | |
| 3pgh | FLP | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.440 | |
| 3qfa | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.440 | |
| 3uzz | TES | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.440 | |
| 4pne | SAH | Methyltransferase-like protein | / | 0.440 | |
| 4tmb | FMN | Old yellow enzyme | / | 0.440 | |
| 4wfr | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.440 | |
| 4x7w | MVI | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.440 |