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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3iw4LW4Protein kinase C alpha type2.7.11.13

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
3iw4LW4Protein kinase C alpha type2.7.11.131.000
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.559
1xwsBI1Serine/threonine-protein kinase pim-12.7.11.10.558
1yi4ADNSerine/threonine-protein kinase pim-12.7.11.10.558
2i0ePDSProtein kinase C beta type2.7.11.130.554
2jedLG8Protein kinase C theta type2.7.11.130.553
2j2iLY4Serine/threonine-protein kinase pim-12.7.11.10.551
3c4eC4ESerine/threonine-protein kinase pim-12.7.11.10.544
4qmxH8HSerine/threonine-protein kinase 242.7.11.10.540
2o65MYFSerine/threonine-protein kinase pim-12.7.11.10.537
3cy3JN5Serine/threonine-protein kinase pim-12.7.11.10.535
4lm5Q17Serine/threonine-protein kinase pim-12.7.11.10.532
4achKDIGlycogen synthase kinase-3 beta2.7.11.260.530
2bikBI1Serine/threonine-protein kinase pim-12.7.11.10.526
3pjcPJCTyrosine-protein kinase JAK32.7.10.20.526
4k0y1OASerine/threonine-protein kinase pim-12.7.11.10.526
4dtk7LISerine/threonine-protein kinase pim-12.7.11.10.525
3jxwLXGSerine/threonine-protein kinase pim-12.7.11.10.524
4n702HXSerine/threonine-protein kinase pim-12.7.11.10.521
4qmnDB8Serine/threonine-protein kinase 242.7.11.10.518
5dgzL20Serine/threonine-protein kinase pim-12.7.11.10.516
3uixQ17Serine/threonine-protein kinase pim-12.7.11.10.513
4qmySTUSerine/threonine-protein kinase 242.7.11.10.513
4a7cE46Serine/threonine-protein kinase pim-12.7.11.10.512
1yi3LY2Serine/threonine-protein kinase pim-12.7.11.10.511
4acg6LQGlycogen synthase kinase-3 beta2.7.11.260.511
4othDRNSerine/threonine-protein kinase N1/0.511
1yhsSTUSerine/threonine-protein kinase pim-12.7.11.10.510
2hog710Serine/threonine-protein kinase Chk12.7.11.10.507
3bgpVX1Serine/threonine-protein kinase pim-12.7.11.10.506
3zh8C58Protein kinase C iota type2.7.11.130.506
4j97ACPFibroblast growth factor receptor 2/0.506
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.505
2bilBI1Serine/threonine-protein kinase pim-12.7.11.10.503
4lmuQUESerine/threonine-protein kinase pim-12.7.11.10.502
4gg50J3Hepatocyte growth factor receptor2.7.10.10.501
4qmpDKISerine/threonine-protein kinase 242.7.11.10.501
2ow3BIMGlycogen synthase kinase-3 beta2.7.11.260.500
3dcv55ESerine/threonine-protein kinase pim-12.7.11.10.500
4gg70J8Hepatocyte growth factor receptor2.7.10.10.498
2r0uM54Serine/threonine-protein kinase Chk12.7.11.10.497
2vd5BI8Myotonin-protein kinase2.7.11.10.496
3r02UNMSerine/threonine-protein kinase pim-12.7.11.10.496
4afjSJJGlycogen synthase kinase-3 beta2.7.11.260.496
4qms1N1Serine/threonine-protein kinase 242.7.11.10.496
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.495
4k181OBSerine/threonine-protein kinase pim-12.7.11.10.495
4wboANWRhodopsin kinase/0.495
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.494
2gcdSTUSerine/threonine-protein kinase TAO22.7.11.10.494
4bchT7ZCyclin-dependent kinase 92.7.11.220.494
4mbl26LSerine/threonine-protein kinase pim-12.7.11.10.494
1oi9N20Cyclin-dependent kinase 22.7.11.220.493
2bdjHETProto-oncogene tyrosine-protein kinase Src2.7.10.20.493
4c02TAKActivin receptor type-12.7.11.300.493
4gmy0X5Tyrosine-protein kinase JAK2/0.493
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.492
2ittAEEEpidermal growth factor receptor2.7.10.10.492
3bgzVX3Serine/threonine-protein kinase pim-12.7.11.10.492
4n6z2HWSerine/threonine-protein kinase pim-12.7.11.10.492
4qmzB49Serine/threonine-protein kinase 242.7.11.10.492
2of2547Tyrosine-protein kinase Lck2.7.10.20.491
3bgqVX2Serine/threonine-protein kinase pim-12.7.11.10.490
2c3kABOSerine/threonine-protein kinase Chk12.7.11.10.489
4ftm1HKSerine/threonine-protein kinase Chk12.7.11.10.489
2xj1XJ1Serine/threonine-protein kinase pim-12.7.11.10.488
2xikJ60Serine/threonine-protein kinase 252.7.11.10.487
2xiyXIYSerine/threonine-protein kinase pim-12.7.11.10.487
4jq7KJQEpidermal growth factor receptor2.7.10.10.486
2r7b2533-phosphoinositide-dependent protein kinase 12.7.11.10.485
4ftkH9KSerine/threonine-protein kinase Chk12.7.11.10.485
4jrvKJVEpidermal growth factor receptor2.7.10.10.485
5e8wSTUTGF-beta receptor type-12.7.11.300.485
2xizXIZSerine/threonine-protein kinase pim-12.7.11.10.484
4qnaX11Serine/threonine-protein kinase 242.7.11.10.484
2itpAEEEpidermal growth factor receptor2.7.10.10.483
3a4pDFQHepatocyte growth factor receptor2.7.10.10.483
3vbq0F5Serine/threonine-protein kinase pim-12.7.11.10.483
4fic0ULProto-oncogene tyrosine-protein kinase Src2.7.10.20.483
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.482
3dtcVINMitogen-activated protein kinase kinase kinase 92.7.11.250.482
1nvrSTUSerine/threonine-protein kinase Chk12.7.11.10.481
2wgjVGHHepatocyte growth factor receptor2.7.10.10.481
3blrCPBCyclin-dependent kinase 92.7.11.220.481
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.481
1r0eDFNGlycogen synthase kinase-3 beta2.7.11.260.480
2qhm7CSSerine/threonine-protein kinase Chk12.7.11.10.480
3ncgBK1Calmodulin-domain protein kinase 1, putative/0.480
4i22IREEpidermal growth factor receptor2.7.10.10.480
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.480
3a7hATPSerine/threonine-protein kinase 242.7.11.10.479
3ckxSTUSerine/threonine-protein kinase 242.7.11.10.479
3gubGUBDeath-associated protein kinase 12.7.11.10.479
4nks2M2Fibroblast growth factor receptor 1/0.479
1okySTU3-phosphoinositide-dependent protein kinase 12.7.11.10.478
4b7tCWTGlycogen synthase kinase-3 beta2.7.11.260.478
4bznUGXSerine/threonine-protein kinase pim-12.7.11.10.478
3a60STURibosomal protein S6 kinase beta-12.7.11.10.476
4fnyI3KALK tyrosine kinase receptor2.7.10.10.476
4hni16WCasein kinase I isoform epsilon2.7.11.10.476
4nka2K7Fibroblast growth factor receptor 1/0.476
1pkdUCNCyclin-dependent kinase 22.7.11.220.475
2qo9ANPEphrin type-A receptor 32.7.10.10.475
2wkmPFYHepatocyte growth factor receptor2.7.10.10.475
3f883HTGlycogen synthase kinase-3 beta2.7.11.260.475
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.475
4hyi1AOSerine/threonine-protein kinase Chk12.7.11.10.475
1qpdSTUTyrosine-protein kinase Lck2.7.10.20.474
3uyt0CKCasein kinase I isoform delta2.7.11.10.474
4u9aSTUInterleukin-1 receptor-associated kinase 42.7.11.10.474
1zrzBI1Protein kinase C iota type2.7.11.130.473
2e9oA58Serine/threonine-protein kinase Chk12.7.11.10.473
3oom507Activin receptor type-12.7.11.300.473
4gk2L66Ephrin type-A receptor 32.7.10.10.473
1eh4IC1Casein kinase I homolog 12.7.11.10.472
2j0j4STFocal adhesion kinase 12.7.10.20.472
3cjgKIMVascular endothelial growth factor receptor 22.7.10.10.472
3gb2G3BGlycogen synthase kinase-3 beta2.7.11.260.472
4acdGR9Glycogen synthase kinase-3 beta2.7.11.260.472
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.472
4qmlANPSerine/threonine-protein kinase 242.7.11.10.472
2acxANPG protein-coupled receptor kinase 62.7.11.160.471
2iw84SPCyclin-dependent kinase 22.7.11.220.471
2objVRVSerine/threonine-protein kinase pim-12.7.11.10.471
3q9xEMOCasein kinase II subunit alpha2.7.11.10.471
4acc7YGGlycogen synthase kinase-3 beta2.7.11.260.471
5cvhADPCasein kinase II subunit alpha2.7.11.10.471
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.470
3l1sZ92Glycogen synthase kinase-3 beta2.7.11.260.470
3t8oATPRhodopsin kinase/0.470
4g2fC07Ephrin type-A receptor 32.7.10.10.470
4hyh1AMSerine/threonine-protein kinase Chk12.7.11.10.470
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.470
2h8hH8HProto-oncogene tyrosine-protein kinase Src2.7.10.20.469
2ym6YM6Serine/threonine-protein kinase Chk12.7.11.10.469
3du8553Glycogen synthase kinase-3 beta2.7.11.260.469
4dymIYZActivin receptor type-12.7.11.300.469
4grb0XGCasein kinase II subunit alpha2.7.11.10.469
1oiyN41Cyclin-dependent kinase 22.7.11.220.468
3tkh07SSerine/threonine-protein kinase Chk12.7.11.10.468
4f630S7Fibroblast growth factor receptor 1/0.468
2ym44YMSerine/threonine-protein kinase Chk12.7.11.10.467
3a62STURibosomal protein S6 kinase beta-12.7.11.10.467
3c4xATPRhodopsin kinase/0.467
3el8PD5Proto-oncogene tyrosine-protein kinase Src2.7.10.20.467
3gc9B45Mitogen-activated protein kinase 112.7.11.240.467
2c475IDCasein kinase I isoform gamma-2/0.466
3jpv1DRSerine/threonine-protein kinase pim-12.7.11.10.466
3kf7L9GMitogen-activated protein kinase 14/0.466
3qf9NM8Serine/threonine-protein kinase pim-12.7.11.10.466
3r2b05BMAP kinase-activated protein kinase 22.7.11.10.466
4bgg844Activin receptor type-12.7.11.300.466
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.466
5ar4SB2Receptor-interacting serine/threonine-protein kinase 22.7.11.10.466
4kb81QNCasein kinase I isoform delta2.7.11.10.465
4yuqKS1Calmodulin-like domain protein kinase/0.465
1bygSTUTyrosine-protein kinase CSK/0.464
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.464
2xf04UBSerine/threonine-protein kinase Chk12.7.11.10.464
3kn5ANPRibosomal protein S6 kinase alpha-52.7.11.10.464
3lcdBDYMacrophage colony-stimulating factor 1 receptor2.7.10.10.464
3vs7KS1Tyrosine-protein kinase HCK2.7.10.20.464
3zep1NXTyrosine-protein kinase JAK32.7.10.20.464
4bzo676Serine/threonine-protein kinase pim-12.7.11.10.464
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.464
4e4m0NHTyrosine-protein kinase JAK2/0.464
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.463
2ydiYDISerine/threonine-protein kinase Chk12.7.11.10.463
4a06ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.463
4dgo0JWCasein kinase II subunit alpha2.7.11.10.463
1nxkSTUMAP kinase-activated protein kinase 22.7.11.10.462
2pzpACPFibroblast growth factor receptor 2/0.462
3dgaRJ1Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.462
3zc5W9ZHepatocyte growth factor receptor2.7.10.10.462
4erwSTUCyclin-dependent kinase 22.7.11.220.462
4fsqHK3Serine/threonine-protein kinase Chk12.7.11.10.462
4fstHK4Serine/threonine-protein kinase Chk12.7.11.10.462
4kba1QMCasein kinase I isoform delta2.7.11.10.462
4l7sG7KTyrosine-protein kinase ITK/TSK2.7.10.20.462
1h1s4SPCyclin-dependent kinase 22.7.11.220.461
3el7PD3Proto-oncogene tyrosine-protein kinase Src2.7.10.20.461
3mvl38PMitogen-activated protein kinase 14/0.461
3r0tFU9Casein kinase II subunit alpha2.7.11.10.461
1kl2FONSerine hydroxymethyltransferase/0.460
2broDF2Serine/threonine-protein kinase Chk12.7.11.10.460
2ym5YM5Serine/threonine-protein kinase Chk12.7.11.10.460
3gwfFADCyclohexanone monooxygenase/0.460
3l8p0CEAngiopoietin-1 receptor2.7.10.10.460
3naxMP73-phosphoinositide-dependent protein kinase 12.7.11.10.460
3zbx6XEHepatocyte growth factor receptor2.7.10.10.460
4aoi4K0Hepatocyte growth factor receptor2.7.10.10.460
4riyADPEpidermal growth factor receptor2.7.10.10.460
2br1PFPSerine/threonine-protein kinase Chk12.7.11.10.459
2gs7ANPEpidermal growth factor receptor2.7.10.10.459
2wmuZYUSerine/threonine-protein kinase Chk12.7.11.10.459
3a7jADPSerine/threonine-protein kinase 242.7.11.10.459
3c1xCKKHepatocyte growth factor receptor2.7.10.10.459
3sd0TSKGlycogen synthase kinase-3 beta2.7.11.260.459
4bddZ0OSerine/threonine-protein kinase Chk22.7.11.10.459
4ftcH6KSerine/threonine-protein kinase Chk12.7.11.10.459
4jia1K3Tyrosine-protein kinase JAK2/0.459
5bvw1N1Epithelial discoidin domain-containing receptor 12.7.10.10.459
4bdcODHSerine/threonine-protein kinase Chk22.7.11.10.458
4mxxDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.458
1g5sI17Cyclin-dependent kinase 22.7.11.220.457
1stcSTUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.457
2ivuZD6Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.457
2z2w770Wee1-like protein kinase2.7.10.20.457
4i41MIXSerine/threonine-protein kinase pim-12.7.11.10.457
4kb81QOCasein kinase I isoform delta2.7.11.10.457
5aacVGHALK tyrosine kinase receptor2.7.10.10.457
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.456
2py3ACPFibroblast growth factor receptor 2/0.456
2y6o1N1Ephrin type-A receptor 42.7.10.10.456
2zva1N1Tyrosine-protein kinase Lyn2.7.10.20.456
3a99ANPSerine/threonine-protein kinase pim-12.7.11.10.456
3ac1KZITyrosine-protein kinase Lck2.7.10.20.456
4qo9627Serine/threonine-protein kinase 242.7.11.10.456
4xey1N1Tyrosine-protein kinase ABL12.7.10.20.456
5d12G97Proto-oncogene tyrosine-protein kinase Src2.7.10.20.456
2brhDFWSerine/threonine-protein kinase Chk12.7.11.10.455
2i40BLZCyclin-dependent kinase 22.7.11.220.455
2uzlC94Cyclin-dependent kinase 22.7.11.220.455
2yfxVGHALK tyrosine kinase receptor2.7.10.10.455
3cy2MB9Serine/threonine-protein kinase pim-12.7.11.10.455
3vs4VSFTyrosine-protein kinase HCK2.7.10.20.455
4ez50RSCyclin-dependent kinase 62.7.11.220.455
1uvrBI83-phosphoinositide-dependent protein kinase 12.7.11.10.454
2c3iIYZSerine/threonine-protein kinase pim-12.7.11.10.454
2i0y5CNMacrophage colony-stimulating factor 1 receptor2.7.10.10.454
2of4979Tyrosine-protein kinase Lck2.7.10.20.454
2wotZZGTGF-beta receptor type-12.7.11.300.454
2xchCKG3-phosphoinositide-dependent protein kinase 12.7.11.10.454
3csdEMOPutative ketoacyl reductase1.3.10.454
3zrlZRLGlycogen synthase kinase-3 beta2.7.11.260.454
4anmWULCasein kinase II subunit alpha2.7.11.10.454
1h1r6CPCyclin-dependent kinase 22.7.11.220.453
2chlDKICasein kinase I isoform gamma-32.7.11.10.453
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.453
3js2VM1Fibroblast growth factor receptor 1/0.453
3zze6XPHepatocyte growth factor receptor2.7.10.10.453
4deg0JJHepatocyte growth factor receptor2.7.10.10.453
4ewqMWLMitogen-activated protein kinase 14/0.453
4ft0HK9Serine/threonine-protein kinase Chk12.7.11.10.453
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.452
3bhtMFRCyclin-dependent kinase 22.7.11.220.452
3c50ADPRhodopsin kinase/0.452
4dfn0K1Tyrosine-protein kinase SYK2.7.10.20.452
4fob0USALK tyrosine kinase receptor2.7.10.10.452
4ftn2HKSerine/threonine-protein kinase Chk12.7.11.10.452
4jqeANPCasein kinase II subunit alpha2.7.11.10.452
4k1b1OCSerine/threonine-protein kinase pim-12.7.11.10.452
4xli1N1Abelson tyrosine-protein kinase 22.7.10.20.452
5cpbNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.452
2j0m4STFocal adhesion kinase 12.7.10.20.451
3cblSTUTyrosine-protein kinase Fes/Fps2.7.10.20.451
3qd33Q53-phosphoinositide-dependent protein kinase 12.7.11.10.451
4ct1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.451
4iarERM5-hydroxytryptamine receptor 1B/0.451
4nc3ERM5-hydroxytryptamine receptor 2B/0.451
4wkqIREEpidermal growth factor receptor2.7.10.10.451
5aaaVGHALK tyrosine kinase receptor2.7.10.10.451
5ackATP3-phosphoinositide-dependent protein kinase 12.7.11.10.451
2f2cAP9Cyclin-dependent kinase 62.7.11.220.450
2iw94SPCyclin-dependent kinase 22.7.11.220.450
2pwlACPFibroblast growth factor receptor 2/0.450
2wmxZY6Serine/threonine-protein kinase Chk12.7.11.10.450
2xyuQ9GEphrin type-A receptor 42.7.10.10.450
2ym7YM7Serine/threonine-protein kinase Chk12.7.11.10.450
3hx4ANPCalmodulin-domain protein kinase 1/0.450
3tnwF18Cyclin-dependent kinase 22.7.11.220.450
4hnf16WCasein kinase I isoform delta2.7.11.10.450
4j711JXGlycogen synthase kinase-3 beta2.7.11.260.450
4mxoDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.450
1oiuN76Cyclin-dependent kinase 22.7.11.220.449
1okzUCN3-phosphoinositide-dependent protein kinase 12.7.11.10.449
2c6tDT5Cyclin-dependent kinase 22.7.11.220.449
2r5tANPSerine/threonine-protein kinase Sgk12.7.11.10.449
2w06FRVCyclin-dependent kinase 22.7.11.220.449
3ofm4B0Casein kinase II subunit alpha'2.7.11.10.449
4iaq2GM5-hydroxytryptamine receptor 1B/0.449
4iebANPCalmodulin-domain protein kinase 1/0.449
4jib1L6cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.449
4qa0SHHHistone deacetylase 83.5.1.980.449
4yx6FMNOmega-3 polyunsaturated fatty acid synthase subunit PfaD/0.449
1q4l679Glycogen synthase kinase-3 beta2.7.11.260.448
2aqhNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.448
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.448
2pz5ACPFibroblast growth factor receptor 2/0.448
2y1oT26UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.448
3hrcATP3-phosphoinositide-dependent protein kinase 12.7.11.10.448
3nga3NGCasein kinase II subunit alpha2.7.11.10.448
4aojV4ZHigh affinity nerve growth factor receptor2.7.10.10.448
4fg7ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.448
4wa9AXITyrosine-protein kinase ABL12.7.10.20.448
1g67TZPThiamine-phosphate synthase/0.447
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.447
1r78FMDCyclin-dependent kinase 22.7.11.220.447
1ywrLI9Mitogen-activated protein kinase 14/0.447
2c3lIDZSerine/threonine-protein kinase Chk12.7.11.10.447
2j4z626Aurora kinase A2.7.11.10.447
3ag9A02cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.447
3be9P04Casein kinase II subunit alpha2.7.11.10.447
3cqeP91Wee1-like protein kinase2.7.10.20.447
3e5aVX6Aurora kinase A2.7.11.10.447
3iaeD7KBenzaldehyde lyase/0.447
3ma301ISerine/threonine-protein kinase pim-12.7.11.10.447
4a8v2ANMajor pollen allergen Bet v 1-J/0.447
4bdhWVISerine/threonine-protein kinase Chk22.7.11.10.447
4dgnLU2Casein kinase II subunit alpha2.7.11.10.447
4gii0X6Non-receptor tyrosine-protein kinase TYK22.7.10.20.447
4hgt15GCasein kinase I isoform delta2.7.11.10.447
4nm0ADPGlycogen synthase kinase-3 beta2.7.11.260.447
4xhgADPUncharacterized protein/0.447
1q20PLOSulfotransferase family cytosolic 2B member 12.8.2.20.446
1wvxBD4Death-associated protein kinase 12.7.11.10.446
1zeoC01Peroxisome proliferator-activated receptor gamma/0.446
2bdf24AProto-oncogene tyrosine-protein kinase Src2.7.10.20.446
3bu5ATPInsulin receptor2.7.10.10.446
3cth319Hepatocyte growth factor receptor2.7.10.10.446
3gxlQIGTGF-beta receptor type-12.7.11.300.446
3uagUMAUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.446
4dquNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.446
4gih0X5Non-receptor tyrosine-protein kinase TYK22.7.10.20.446
4kikKSAInhibitor of nuclear factor kappa-B kinase subunit beta2.7.11.100.446
4qmtH1NSerine/threonine-protein kinase 242.7.11.10.446
5e8xSTUTGF-beta receptor type-12.7.11.300.446
1ke6LS2Cyclin-dependent kinase 22.7.11.220.445
2ckeIQUDeath-associated protein kinase 2/0.445
2csnCKICasein kinase I homolog 12.7.11.10.445
2ghlLIBMitogen-activated protein kinase 14/0.445
2j0k4STFocal adhesion kinase 12.7.10.20.445
3bkbSTUTyrosine-protein kinase Fes/Fps2.7.10.20.445
3f82353Hepatocyte growth factor receptor2.7.10.10.445
3hdmMMGSerine/threonine-protein kinase Sgk12.7.11.10.445
3igoANPCalmodulin-domain protein kinase 1, putative/0.445
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.445
3vjoANPEpidermal growth factor receptor2.7.10.10.445
4fjz4FJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
4flh14KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
4fszHK8Serine/threonine-protein kinase Chk12.7.11.10.445
4hvh19RTyrosine-protein kinase JAK32.7.10.20.445
4lggVGGProto-oncogene tyrosine-protein kinase Src2.7.10.20.445
4lopSB4Mitogen-activated protein kinase 14/0.445
1draMTXDihydrofolate reductase1.5.1.30.444
1e9hINRCyclin-dependent kinase 22.7.11.220.444
1p44GEQEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.444
2acwUPGGlycosyltransferase/0.444
2azzTCHPhospholipase A2, major isoenzyme3.1.1.40.444
2b365PPEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.444
2fgiPD1Fibroblast growth factor receptor 1/0.444
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.444
2pvnP63Casein kinase II subunit alpha2.7.11.10.444
2qmzLDPRibosyldihydronicotinamide dehydrogenase [quinone]/0.444
2xm9LWHSerine/threonine-protein kinase Chk22.7.11.10.444
3b2tM33Fibroblast growth factor receptor 2/0.444
3lctADPALK tyrosine kinase receptor2.7.10.10.444
3ml8ML8Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
3qlg1N1Proto-oncogene tyrosine-protein kinase Src2.7.10.20.444
3w1f1O5Dual specificity protein kinase TTK2.7.12.10.444
4c61LMMTyrosine-protein kinase JAK2/0.444
4feq0T8Tyrosine-protein kinase receptor TYRO32.7.10.10.444
4fex0TOAminoglycoside 3'-phosphotransferase AphA1-IAB/0.444
4fhk0U0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.10.444
4hgl0YOCasein kinase I isoform gamma-32.7.11.10.444
4kbk1QGCasein kinase I isoform delta2.7.11.10.444
4mcv29KProto-oncogene tyrosine-protein kinase Src2.7.10.20.444
1o6yACPSerine/threonine-protein kinase PknB2.7.11.10.443
1rw8580TGF-beta receptor type-12.7.11.300.443
1yolS03Proto-oncogene tyrosine-protein kinase Src2.7.10.20.443
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.443
2pe15173-phosphoinositide-dependent protein kinase 12.7.11.10.443
2ym3YM3Serine/threonine-protein kinase Chk12.7.11.10.443
3dt1P40Mitogen-activated protein kinase 14/0.443
3h4vNAPPteridine reductase 11.5.1.330.443
3hllI45Mitogen-activated protein kinase 14/0.443
3kpkFADSulfide-quinone reductase/0.443
3mtlFEFCyclin-dependent kinase 162.7.11.220.443
3q3b55EGlycogen synthase kinase-3 beta2.7.11.260.443
3umxQ18Serine/threonine-protein kinase pim-12.7.11.10.443
3zewSTUEphrin type-B receptor 42.7.10.10.443
4ftu7HKSerine/threonine-protein kinase Chk12.7.11.10.443
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.443
1bvrNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.442
1e8xATPPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.442
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.442
2izrBRKCasein kinase I isoform gamma-32.7.11.10.442
2wugHPK4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase3.7.1.170.442
2xa4AZ5Tyrosine-protein kinase JAK2/0.442
3qqkX02Cyclin-dependent kinase 22.7.11.220.442
3uicNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.442
4bidIE8Mitogen-activated protein kinase kinase kinase 52.7.11.250.442
4fjyFJYPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
4fsuHK5Serine/threonine-protein kinase Chk12.7.11.10.442
4nk92K5Fibroblast growth factor receptor 1/0.442
4oacADPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.442
3pwhZMAAdenosine receptor A2a/0.442
1finATPCyclin-dependent kinase 22.7.11.220.441
1gih1PUCyclin-dependent kinase 22.7.11.220.441
1j3iWRABifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.441
1jolFFODihydrofolate reductase1.5.1.30.441
1xjdSTUProtein kinase C theta type2.7.11.130.441
2in6839Wee1-like protein kinase2.7.10.20.441
2vagV25Dual specificity protein kinase CLK12.7.12.10.441
2wihP48Cyclin-dependent kinase 22.7.11.220.441
2wxvWXVCyclin-dependent kinase 22.7.11.220.441
3ac3KSHTyrosine-protein kinase Lck2.7.10.20.441
3ctj320Hepatocyte growth factor receptor2.7.10.10.441
3irn1CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.441
3kjsDQ1Bifunctional dihydrofolate reductase-thymidylate synthase/0.441
3l9lL9LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.441
3wowANPCasein kinase II subunit alpha2.7.11.10.441
4c4h7RODual specificity protein kinase TTK2.7.12.10.441
4gk4L90Ephrin type-A receptor 32.7.10.10.441
5auwQUEDeath-associated protein kinase 12.7.11.10.441
1g4sTPSThiamine-phosphate synthase/0.440
1ir3ANPInsulin receptor2.7.10.10.440
1ouk084Mitogen-activated protein kinase 14/0.440
1v35NAIEnoyl-ACP reductase/0.440
2ayp43ASerine/threonine-protein kinase Chk12.7.11.10.440
2ivvPP1Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.440
2pvyACPFibroblast growth factor receptor 2/0.440
2w0jZATSerine/threonine-protein kinase Chk22.7.11.10.440
2wmqZYQSerine/threonine-protein kinase Chk12.7.11.10.440
2ydkYDKSerine/threonine-protein kinase Chk12.7.11.10.440
3i81EBIInsulin-like growth factor 1 receptor2.7.10.10.440
3mdvCL6Cholesterol 24-hydroxylase/0.440
3zrmZRMGlycogen synthase kinase-3 beta2.7.11.260.440
4bb432WEphrin type-B receptor 42.7.10.10.440
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.440
4gj20XHNon-receptor tyrosine-protein kinase TYK22.7.10.20.440
4gk3L87Ephrin type-A receptor 32.7.10.10.440
4h9506UDihydrofolate reductase1.5.1.30.440
4l425FIRibosomal protein S6 kinase beta-12.7.11.10.440
4loqSB4Mitogen-activated protein kinase 14/0.440