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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
5cx6CDPRNA-dependent RNA polymerase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
5cx6CDPRNA-dependent RNA polymerase/1.000
3e2sFADBifunctional protein PutA1.5.5.20.545
1tj2FADBifunctional protein PutA1.5.5.20.535
1tj1FADBifunctional protein PutA1.5.5.20.528
2yvfFADFerredoxin reductase/0.524
4o8aFADBifunctional protein PutA1.2.1.880.519
2fznFADBifunctional protein PutA1.5.5.20.518
2a8xFADDihydrolipoyl dehydrogenase1.8.1.40.515
1jklANPDeath-associated protein kinase 12.7.11.10.505
1xkkFMMEpidermal growth factor receptor2.7.10.10.503
1rfqLARActin, alpha skeletal muscle/0.502
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.501
1msnJE2Gag-Pol polyprotein3.4.23.160.500
3vfa031Gag-Pol polyprotein3.4.23.160.500
2fzmFADBifunctional protein PutA1.5.5.20.499
2qhm7CSSerine/threonine-protein kinase Chk12.7.11.10.499
1svhI08cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.498
3zo4QWIcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.498
5fdg0N8Polymerase acidic protein/0.496
1rejB1LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.495
1tj0FADBifunctional protein PutA1.5.5.20.494
3lpfZ77Beta-glucuronidase3.2.1.310.493
1ijjLARActin, alpha skeletal muscle/0.490
2a41ATPActin, alpha skeletal muscle/0.490
3hazFADBifunctional protein PutA/0.490
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.489
2hxq373Serine/threonine-protein kinase Chk12.7.11.10.489
3w33W19Epidermal growth factor receptor2.7.10.10.489
1d4jMSCGag-Pol polyprotein3.4.23.160.488
3sfeFADSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial/0.488
1msmJE2Gag-Pol polyprotein3.4.23.160.487
1xh9R69cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.487
4djhJDCKappa-type opioid receptor/0.486
3bgcLJHGag-Pol polyprotein3.4.23.160.484
4axaRKDcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.484
1ppl1Z7Penicillopepsin-13.4.23.200.483
1tqmANPRIO-type serine/threonine-protein kinase Rio22.7.11.10.483
2ojf4PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.483
3t3c017Gag-Pol polyprotein3.4.23.160.483
2vrx447Aurora kinase B-A2.7.11.10.482
4x7vMIVMycinamicin III 3''-O-methyltransferase2.1.1.2370.482
1xl5190Gag-Pol polyprotein3.4.23.160.481
3cyw017Gag-Pol polyprotein3.4.23.160.481
3vrzVRZTyrosine-protein kinase HCK2.7.10.20.481
4njsG08Protease/0.481
2bqvA1AProtease/0.480
3rgaLSBEpoxide hydrolase LasB5.5.10.480
1qcfPP1Tyrosine-protein kinase HCK2.7.10.20.479
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.479
2jdsL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.478
2pwrG4GGag-Pol polyprotein3.4.23.160.478
3elySAHMethyltransferase/0.478
3nu6478Gag-Pol polyprotein3.4.23.160.478
4m52FADDihydrolipoyl dehydrogenase1.8.1.40.478
3kddJZQGag-Pol polyprotein3.4.23.160.477
4wq5ATPtRNA N6-adenosine threonylcarbamoyltransferase/0.477
1c2tNHSPhosphoribosylglycinamide formyltransferase/0.476
1d4hBEHGag-Pol polyprotein3.4.23.160.476
1kzkJE2Gag-Pol polyprotein3.4.23.160.476
4a6bQG8Gag-Pol polyprotein3.4.23.160.476
4ftkH9KSerine/threonine-protein kinase Chk12.7.11.10.476
2jdtI5ScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.475
2oh02PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.475
2qaeFADDihydrolipoyl dehydrogenase1.8.1.40.475
2vojNADAlanine dehydrogenase1.4.1.10.475
3ekv478Gag-Pol polyprotein3.4.23.160.475
4ft5H2KSerine/threonine-protein kinase Chk12.7.11.10.475
4uirFADOleate hydratase4.2.1.530.475
1h5rTHMGlucose-1-phosphate thymidylyltransferase 1/0.474
3srzUPGToxin A/0.474
1mrwK57Gag-Pol polyprotein3.4.23.160.473
1q8uH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.473
1q8wM77cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.473
1xdiFADNAD(P)H dehydrogenase (quinone)/0.473
3nls016Gag-Pol polyprotein3.4.23.160.473
3oagLPQRenin3.4.23.150.473
4hyi1AOSerine/threonine-protein kinase Chk12.7.11.10.473
1kf6FADFumarate reductase flavoprotein subunit1.3.5.40.472
1npvL27Gag-Pol polyprotein3.4.23.160.472
1xh4R69cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.472
2c0iL1GTyrosine-protein kinase HCK2.7.10.20.472
3r4b74TGag-Pol polyprotein/0.472
1ppm0P1Penicillopepsin-13.4.23.200.471
1wbk568Pol protein/0.471
3bbtFMMReceptor tyrosine-protein kinase erbB-42.7.10.10.471
3ko0TFPProtein S100-A4/0.471
4s34ANPMitogen-activated protein kinase 12.7.11.240.471
2azyCHDPhospholipase A2, major isoenzyme3.1.1.40.470
3pgiF41Endothiapepsin3.4.23.220.470
1t7i017Gag-Pol polyprotein3.4.23.160.469
2qfxNDPIsocitrate dehydrogenase [NADP], mitochondrial1.1.1.420.469
2v00V15Endothiapepsin3.4.23.220.469
2vo7M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.469
2z02ATPPhosphoribosylaminoimidazole-succinocarboxamide synthase6.3.2.60.469
3qd03Q43-phosphoinositide-dependent protein kinase 12.7.11.10.469
4b1uLABActin, alpha skeletal muscle/0.469
4fsuHK5Serine/threonine-protein kinase Chk12.7.11.10.469
4jhz1KVBeta-glucuronidase3.2.1.310.469
4kx6FADFumarate reductase flavoprotein subunit1.3.5.40.469
1bv9XV6Gag-Pol polyprotein3.4.23.160.468
1kiaSAMGlycine N-methyltransferase2.1.1.200.468
1xh6R94cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.468
2c3lIDZSerine/threonine-protein kinase Chk12.7.11.10.468
2hog710Serine/threonine-protein kinase Chk12.7.11.10.468
2vgpAD6Aurora kinase B-A2.7.11.10.468
3i7eDJRGag-Pol polyprotein/0.468
3n0tOPYDipeptidyl peptidase 23.4.14.20.468
4y8wSTRSteroid 21-hydroxylase/0.468
1tqpATPRIO-type serine/threonine-protein kinase Rio22.7.11.10.467
2bpw1INGag-Pol polyprotein3.4.23.160.467
2itpAEEEpidermal growth factor receptor2.7.10.10.467
2uw5GVNcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.467
3bgbLJGGag-Pol polyprotein3.4.23.160.467
3o99K13Pol polyprotein/0.467
4fsqHK3Serine/threonine-protein kinase Chk12.7.11.10.467
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.10.467
1d4sTPVGag-Pol polyprotein3.4.23.160.466
1hvrXK2Gag-Pol polyprotein/0.466
1sdvMK1Gag-Pol polyprotein3.4.23.160.466
1sveI01cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.466
1xhaR68cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.466
2f5zFADDihydrolipoyl dehydrogenase, mitochondrial1.8.1.40.466
2qnqQN3Gag-Pol polyprotein3.4.23.160.466
3i12ADPD-alanine--D-alanine ligase A6.3.2.40.466
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.466
4f6s0SQCyclin-dependent kinase 82.7.11.220.466
1c6yMK1Protease/0.465
1ff02NCGag-Pol polyprotein3.4.23.160.465
1rbmKT5Trifunctional purine biosynthetic protein adenosine-32.1.2.20.465
2amt1AA2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase4.6.1.120.465
2bpv1INGag-Pol polyprotein3.4.23.160.465
2qi6MZ8Gag-Pol polyprotein/0.465
2qu6857Vascular endothelial growth factor receptor 22.7.10.10.465
2r43G3GGag-Pol polyprotein3.4.23.160.465
2ylzFADPhenylacetone monooxygenase1.14.13.920.465
3uhl2NCGag-Pol polyprotein3.4.23.160.465
4a6cQG9Gag-Pol polyprotein3.4.23.160.465
4ctkSAMGenome polyprotein/0.465
4dggI76Proto-oncogene tyrosine-protein kinase Src2.7.10.20.465
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.465
4gh2HK0Serine/threonine-protein kinase Chk12.7.11.10.465
4ih8B43Calmodulin-domain protein kinase 1/0.465
4upjU04Gag-Pol polyprotein/0.465
1zsr0ZTGag-Pol polyprotein3.4.23.160.464
2c0oL2GTyrosine-protein kinase HCK2.7.10.20.464
2f80017Gag-Pol polyprotein3.4.23.160.464
2qmyFADRibosyldihydronicotinamide dehydrogenase [quinone]/0.464
2v51LABActin, alpha skeletal muscle/0.464
1mokFAD2-oxopropyl-CoM reductase, carboxylating1.8.1.50.463
2e9oA58Serine/threonine-protein kinase Chk12.7.11.10.463
2f8g017Gag-Pol polyprotein3.4.23.160.463
2npxFADNADH peroxidase1.11.1.10.463
2r0uM54Serine/threonine-protein kinase Chk12.7.11.10.463
2ydiYDISerine/threonine-protein kinase Chk12.7.11.10.463
3almFAD2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase/0.463
3isjA8DPantothenate synthetase6.3.2.10.463
4gy2LARActin, alpha skeletal muscle/0.463
4jq8KJ8Epidermal growth factor receptor2.7.10.10.463
4jv81M1Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.463
4mb2ATPUncharacterized protein/0.463
4y57F63Endothiapepsin3.4.23.220.463
4ye3G04Gag-Pol polyprotein3.4.23.160.463
4zvlFADRibosyldihydronicotinamide dehydrogenase [quinone]/0.463
1hsgMK1Gag-Pol polyprotein/0.462
1ivq0PXGag-Pol polyprotein/0.462
1k6pXN3Gag-Pol polyprotein3.4.23.160.462
1w5yBE6Gag-Pol polyprotein3.4.23.160.462
1xh7R96cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.462
2qi4MZ6Gag-Pol polyprotein/0.462
2uvzGVJcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.462
2xdoFADTetX family tetracycline inactivation enzyme/0.462
3ogqAB1Pol polyprotein/0.462
3vs0VS0Tyrosine-protein kinase HCK2.7.10.20.462
3w32W32Epidermal growth factor receptor2.7.10.10.462
1m0b0ZQGag-Pol polyprotein3.4.23.160.461
1sguMK1Gag-Pol polyprotein3.4.23.160.461
1w5vBE3Gag-Pol polyprotein3.4.23.160.461
2c1aI5ScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.461
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.461
2gr2APRFerredoxin reductase/0.461
2i0dMUTProtease/0.461
2i4uDJRProtease/0.461
3rukAERSteroid 17-alpha-hydroxylase/17,20 lyase/0.461
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.461
4i22IREEpidermal growth factor receptor2.7.10.10.461
1c3eNHRPhosphoribosylglycinamide formyltransferase/0.460
1daz0Q4Gag-Pol polyprotein3.4.23.160.460
1gx1CDP2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase4.6.1.120.460
1odw0E8Gag-Pol polyprotein3.4.23.160.460
1wbmBLLPol protein/0.460
2v52LABActin, alpha skeletal muscle/0.460
2xbjXBJSerine/threonine-protein kinase Chk22.7.11.10.460
3s43478Protease/0.460
1q6nP90Tyrosine-protein phosphatase non-receptor type 13.1.3.480.459
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.459
2nuaCOASuccinate--CoA ligase [ADP-forming] subunit alpha6.2.1.50.459
2x3nFADProbable FAD-dependent monooxygenase/0.459
2x8eX8ESerine/threonine-protein kinase Chk12.7.11.10.459
3pwwROCEndothiapepsin3.4.23.220.459
4dxd9PCCell division protein FtsZ/0.459
4fszHK8Serine/threonine-protein kinase Chk12.7.11.10.459
4hdpG52Gag-Pol polyprotein3.4.23.160.459
4j2wFADKynurenine 3-monooxygenase/0.459
4j34FADKynurenine 3-monooxygenase/0.459
1rwbNADGlucose 1-dehydrogenase1.1.1.470.458
2eq9FADDihydrolipoyl dehydrogenase/0.458
2qi1MZ4Gag-Pol polyprotein/0.458
2r3tG4GGag-Pol polyprotein3.4.23.160.458
2vhvNAIAlanine dehydrogenase1.4.1.10.458
3ec0GRLGag-Pol polyprotein3.4.23.470.458
3o9gF53Gag-Pol polyprotein/0.458
3sa8K83Protease/0.458
3t7x4SHEndothiapepsin3.4.23.220.458
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.458
3zo1SIJcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.458
4a9uA9USerine/threonine-protein kinase Chk22.7.11.10.458
1a9mU0EGag-Pol polyprotein/0.457
1metDMPGag-Pol polyprotein3.4.23.160.457
1q1wFADPutidaredoxin reductase1.18.1.50.457
1w4xFADPhenylacetone monooxygenase1.14.13.920.457
1wc4APCAdenylate cyclase/0.457
2pwcG3GGag-Pol polyprotein3.4.23.160.457
2pym1UNGag-Pol polyprotein3.4.23.160.457
2wmqZYQSerine/threonine-protein kinase Chk12.7.11.10.457
2wtcVGMSerine/threonine-protein kinase Chk22.7.11.10.457
2ycsNXPSerine/threonine-protein kinase Chk22.7.11.10.457
3a62STURibosomal protein S6 kinase beta-12.7.11.10.457
3dcrKVSProtease/0.457
3iphG11Mitogen-activated protein kinase 14/0.457
3lbySAHUncharacterized protein/0.457
4i8zG08Gag-Pol polyprotein3.4.23.160.457
4k4p3TLGag-Pol polyprotein/0.457
4rphFADUDP-galactopyranose mutase5.4.99.90.457
4ytnFADSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial/0.457
5c3jFADSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial/0.457
1bwaXV6Gag-Pol polyprotein3.4.23.160.456
1ebyBEBGag-Pol polyprotein3.4.23.160.456
1hvsA77Gag-Pol polyprotein/0.456
1sx4ADP60 kDa chaperonin/0.456
1zx9FADMercuric reductase1.16.1.10.456
2ieo017Protease/0.456
2px5SAHGenome polyprotein2.7.7.480.456
3jvwDMPGag-Pol polyprotein3.4.23.160.456
3l9mL9McAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.456
4b1vLABActin, alpha skeletal muscle/0.456
4dt9GMPAPH(2'')-Id/0.456
4iv8SAMPhosphoethanolamine N-methyltransferase,putative/0.456
4qmpDKISerine/threonine-protein kinase 242.7.11.10.456
3pblETQD(3) dopamine receptor/0.456
1bv7XV6Gag-Pol polyprotein3.4.23.160.455
1proA88Gag-Pol polyprotein/0.455
1qo8FADFumarate reductase flavoprotein subunit/0.455
1xddAAYIntegrin alpha-L/0.455
2pyn1UNGag-Pol polyprotein3.4.23.160.455
2qi7MZ9Gag-Pol polyprotein/0.455
2w0jZATSerine/threonine-protein kinase Chk22.7.11.10.455
3l9nL9NcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.455
3lshFADPyranose 2-oxidase/0.455
3stxBKAMethylketone synthase I/0.455
4fnd3H9Enoyl-CoA hydratase/0.455
4fstHK4Serine/threonine-protein kinase Chk12.7.11.10.455
4j54G52Gag-Pol polyprotein3.4.23.160.455
4j5j478Gag-Pol polyprotein3.4.23.160.455
4njuTPVProtease/0.455
4q1x017Gag-Pol polyprotein3.4.23.160.455
4y93746Tyrosine-protein kinase/0.455
3sn6P0GBeta-2 adrenergic receptor/0.455
1hviA77Protease/0.454
1k6vXN2Gag-Pol polyprotein3.4.23.160.454
1qbsDMPGag-Pol polyprotein3.4.23.160.454
1scuCOASuccinate--CoA ligase [ADP-forming] subunit alpha6.2.1.50.454
1t7kBH0Gag-Pol polyprotein3.4.23.160.454
2c0tL3GTyrosine-protein kinase HCK2.7.10.20.454
2pk5075Protease/0.454
2y60M8FIsopenicillin N synthase1.21.3.10.454
3d1z017Gag-Pol polyprotein3.4.23.160.454
3e8eG98cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.454
3lpgZ78Beta-glucuronidase3.2.1.310.454
3lzs017Gag-Pol polyprotein3.4.23.160.454
3ndwRITGag-Pol polyprotein3.4.23.160.454
3oxv478Gag-Pol polyprotein3.4.23.160.454
3vqhIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.454
4dtaADNAPH(2'')-Id/0.454
4ftu7HKSerine/threonine-protein kinase Chk12.7.11.10.454
4fx9FADCoenzyme A disulfide reductase1.8.1.140.454
4hjoAQ4Epidermal growth factor receptor2.7.10.10.454
4rvj478Protease/0.454
1iiq0ZRGag-Pol polyprotein3.4.23.160.453
2bb9AKCGag-Pol polyprotein3.4.23.160.453
2cej1AHPol protein/0.453
2g20L1ARenin3.4.23.150.453
2hs1017Protease/0.453
2nadNADFormate dehydrogenase/0.453
2pc4ASP_TRP_ASNFructose-bisphosphate aldolase4.1.2.130.453
2uzuL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.453
3i2l2NCProtease/0.453
3liqE14Protease/0.453
3pb3SAH16S rRNA (adenine(1408)-N(1))-methyltransferase2.1.1.1800.453
3qvxNADMyo-inositol-1-phosphate synthase (Ino1)/0.453
4ftm1HKSerine/threonine-protein kinase Chk12.7.11.10.453
4j98ACPFibroblast growth factor receptor 2/0.453
4q1y017Gag-Pol polyprotein3.4.23.160.453
4yduADPtRNA N6-adenosine threonylcarbamoyltransferase/0.453
1bdqIM1Gag-Pol polyprotein3.4.23.160.452
1gcoNADGlucose 1-dehydrogenase1.1.1.470.452
1idb0DOGag-Pol polyprotein/0.452
2fdd385Pol protein/0.452
2qo6CHDFatty acid-binding protein 10-A, liver basic/0.452
2qs1UB1Glutamate receptor ionotropic, kainate 1/0.452
2ycrHCWSerine/threonine-protein kinase Chk22.7.11.10.452
2yitYITSerine/threonine-protein kinase Chk22.7.11.10.452
3ds6A17Mitogen-activated protein kinase 14/0.452
3gi6D78Gag-Pol polyprotein/0.452
3gu7ADPDeath-associated protein kinase 12.7.11.10.452
3iewCTP2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase/0.452
3kdcJZPGag-Pol polyprotein3.4.23.160.452
3qrsNK8Gag-Pol polyprotein3.4.23.160.452
3sm2478Putative gag-pro-pol polyprotein/0.452
3tzaTZGGlutamate receptor 2/0.452
4jsjQJ7Nitric oxide synthase, brain1.14.13.390.452
1d4iBEGGag-Pol polyprotein3.4.23.160.451
1k08BZDGlycogen phosphorylase, muscle form2.4.1.10.451
1rw8580TGF-beta receptor type-12.7.11.300.451
2bjhFERFeruloyl esterase A3.1.1.730.451
2c0cNAPProstaglandin reductase 310.451
2c3kABOSerine/threonine-protein kinase Chk12.7.11.10.451
2gu8796cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.451
2ivnANPtRNA N6-adenosine threonylcarbamoyltransferase/0.451
2wkz5AHGag-Pol polyprotein/0.451
2wtdZZKSerine/threonine-protein kinase Chk22.7.11.10.451
3nynSGVG protein-coupled receptor kinase 62.7.11.160.451
3qlg1N1Proto-oncogene tyrosine-protein kinase Src2.7.10.20.451
3qn8NI7Gag-Pol polyprotein3.4.23.160.451
3upjU03Gag-Pol polyprotein/0.451
4ft3H1KSerine/threonine-protein kinase Chk12.7.11.10.451
4jik1KOSerine/threonine-protein kinase Chk12.7.11.10.451
4jin1L7RIO-type serine/threonine-protein kinase Rio12.7.11.10.451
4jrvKJVEpidermal growth factor receptor2.7.10.10.451
1d7yFADFerredoxin reductase/0.450
1dncFADGlutathione reductase, mitochondrial1.8.1.70.450
1ffi2NCGag-Pol polyprotein3.4.23.160.450
1fpyADPGlutamine synthetase6.3.1.20.450
1gvt2ZSEndothiapepsin3.4.23.220.450
1hvjA78Gag-Pol polyprotein/0.450
1k6tXN1Gag-Pol polyprotein3.4.23.160.450
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.450
1vebI05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.450
1w5xBE5Gag-Pol polyprotein3.4.23.160.450
1zmcFADDihydrolipoyl dehydrogenase, mitochondrial1.8.1.40.450
2cduFADNADH oxidase/0.450
2cmvNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.450
2qci065Gag-Pol polyprotein3.4.23.160.450
2r38G4GGag-Pol polyprotein3.4.23.160.450
3aidARQGag-Pol polyprotein3.4.23.160.450
3e8cG96cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.450
3livE16Protease/0.450
3mkhFADNitroalkane oxidase/0.450
3nu9478Gag-Pol polyprotein3.4.23.160.450
3poz03PEpidermal growth factor receptor2.7.10.10.450
3ucb017Gag-Pol polyprotein/0.450
4fvz4KJNitric oxide synthase, brain1.14.13.390.450
4hegG52Gag-Pol polyprotein3.4.23.160.450
4iqlFMNEnoyl-(Acyl-carrier-protein) reductase II/0.450
4jdrFADDihydrolipoyl dehydrogenase1.8.1.40.450
4njvRITProtease/0.450
4ocgFADFAD-dependent pyridine nucleotide-disulphide oxidoreductase/0.450
4y95746Tyrosine-protein kinase/0.450
5jjrSAHGenome polyprotein/0.450
1dssNADGlyceraldehyde-3-phosphate dehydrogenase1.2.1.120.449
1f52ADPGlutamine synthetase6.3.1.20.449
1hbvGANGag-Pol polyprotein/0.449
1j21ATPArgininosuccinate synthase/0.449
2broDF2Serine/threonine-protein kinase Chk12.7.11.10.449
2f3kRO1Protease/0.449
2j7t274Serine/threonine-protein kinase 102.7.11.10.449
2uzvSS5cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.449
2vo0M03cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.449
2ym3YM3Serine/threonine-protein kinase Chk12.7.11.10.449
3own3OWRenin3.4.23.150.449
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.449
3zptM8YGag-Pol polyprotein3.4.23.160.449
4a4qUX9Pol protein/0.449
4ftn2HKSerine/threonine-protein kinase Chk12.7.11.10.449
4fto3HKSerine/threonine-protein kinase Chk12.7.11.10.449
4h1e10JBeta-secretase 13.4.23.460.449
4j31FADKynurenine 3-monooxygenase/0.449
4kzoNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.449
4q1w017Gag-Pol polyprotein3.4.23.160.449
1hpoUNIGag-Pol polyprotein3.4.23.160.448
1kr2TADNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.448
1od10QSEndothiapepsin3.4.23.220.448
1rc0KT5Trifunctional purine biosynthetic protein adenosine-32.1.2.20.448
1sbgIM1Gag-Pol polyprotein/0.448
1t3r017Gag-Pol polyprotein3.4.23.160.448
2cgu3A3Serine/threonine-protein kinase Chk12.7.11.10.448
2i4dQFIProtease/0.448
2jk6FADTrypanothione reductase/0.448
2pqzG0GGag-Pol polyprotein3.4.23.160.448
3mws017Pol protein/0.448
3own3OXRenin3.4.23.150.448
3qd43Q63-phosphoinositide-dependent protein kinase 12.7.11.10.448
3qpjN4IGag-Pol polyprotein3.4.23.160.448
3sa4F72Protease/0.448
3t4nADP5'-AMP-activated protein kinase subunit gamma/0.448
3t99ADPInositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2/0.448
4hyh1AMSerine/threonine-protein kinase Chk12.7.11.10.448
4j55031Gag-Pol polyprotein3.4.23.160.448
4qi5FADCellobiose dehydrogenase/0.448
4qofFMNRibosyldihydronicotinamide dehydrogenase [quinone]/0.448
4zeaIMIEndothiapepsin3.4.23.220.448
1g35AHFGag-Pol polyprotein3.4.23.160.447
1nvfADPPentafunctional AROM polypeptide/0.447
1qbu846Gag-Pol polyprotein3.4.23.160.447
1sqkLARActin, alpha skeletal muscle/0.447
2c1bCQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.447
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.447
2ien017Gag-Pol polyprotein3.4.23.160.447
2iviACWIsopenicillin N synthase1.21.3.10.447
2ivpATPtRNA N6-adenosine threonylcarbamoyltransferase/0.447
2q4bNAPUncharacterized protein At5g02240/0.447
2vhwNAIAlanine dehydrogenase1.4.1.10.447
2wlgSOPPolysialic acid O-acetyltransferase/0.447
2xszATPRuvB-like 23.6.4.120.447
2xyeCXGGag-Pol polyprotein/0.447
3cinNADMyo-inositol-1-phosphate synthase-related protein/0.447
3o9aK14Pol polyprotein/0.447
3oy4017Gag-Pol polyprotein3.4.23.160.447
3t54ATPInositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2/0.447
3w0gW07Vitamin D3 receptor/0.447
1bveDMPGag-Pol polyprotein3.4.23.160.446
1ebdFADDihydrolipoyl dehydrogenase1.8.1.40.446
1mesDMPGag-Pol polyprotein3.4.23.160.446
1nbiSAMGlycine N-methyltransferase2.1.1.200.446
1p9wANPType II secretion system protein E/0.446
1vikBAYGag-Pol polyprotein/0.446
1xh5R68cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.446
1ydtIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.446
2fxdDR7Pol polyprotein/0.446
2jjj0QSEndothiapepsin3.4.23.220.446
2o4pTPVProtease/0.446
2rkfAB1Pol protein/0.446
2yerTQ1Serine/threonine-protein kinase Chk12.7.11.10.446
3amaSKEcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.446
3coy53HPantothenate synthetase6.3.2.10.446
3mwuBK3Calmodulin-domain protein kinase 1, putative/0.446
3nuj478Gag-Pol polyprotein3.4.23.160.446
3rgaILDEpoxide hydrolase LasB5.5.10.446
3w0iO11Vitamin D3 receptor/0.446
4axdANPInositol-pentakisphosphate 2-kinase2.7.1.1580.446
4dqc017Gag-Pol polyprotein/0.446
4f7n0SVCyclin-dependent kinase 82.7.11.220.446
1ajvNMBGag-Pol polyprotein3.4.23.160.445
1dw60Q4Gag-Pol polyprotein3.4.23.160.445
1hshMK1Gag-Pol polyprotein/0.445
1nfbNADInosine-5'-monophosphate dehydrogenase 2/0.445
1yt9OISGag-Pol polyprotein/0.445
2h00SAHU6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase/0.445
2q36ATPActin, alpha skeletal muscle/0.445
2uy0HV1Gag-Pol polyprotein3.4.23.160.445
2wvlGDDMannosyl-3-phosphogylcerate synthase/0.445
2x1nX1NCyclin-dependent kinase 22.7.11.220.445
3c96FADFlavin-containing monooxygenase/0.445
3d20017Gag-Pol polyprotein3.4.23.160.445
3i6oGR6Gag-Pol polyprotein3.4.23.160.445
3iocA5DPantothenate synthetase6.3.2.10.445
3k3bL31Kinesin-like protein KIF11/0.445
3r8vZ62Cyclin-dependent kinase 22.7.11.220.445
3tog079Gag-Pol polyprotein2.7.7.490.445
3tu5ATPActin, alpha skeletal muscle/0.445
3vs7KS1Tyrosine-protein kinase HCK2.7.10.20.445
3zokNAD3-dehydroquinate synthase, chloroplastic4.2.3.40.445
4d03FADPhenylacetone monooxygenase1.14.13.920.445
4dnaFADProbable glutathione reductase/0.445
4fv1EK4Mitogen-activated protein kinase 12.7.11.240.445
4fw05KJNitric oxide synthase, brain1.14.13.390.445
4h380YXDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.445
4i6aHMG3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.880.445
4k110J9Proto-oncogene tyrosine-protein kinase Src2.7.10.20.445
4pd6URINucleoside permease/0.445
4pl8ATPActin, alpha skeletal muscle/0.445
4req5ADMethylmalonyl-CoA mutase large subunit5.4.99.20.445
6upjNIUGag-Pol polyprotein/0.445
7upjINUGag-Pol polyprotein3.4.23.160.445
1bk0ACVIsopenicillin N synthase1.21.3.10.444
1hdcCBO3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.444
1i9c5ADGlutamate mutase epsilon subunit/0.444
1lf2R37Plasmepsin-23.4.23.390.444
2i4xKGQProtease/0.444
2v16C47Renin3.4.23.150.444
2ylsFADPhenylacetone monooxygenase1.14.13.920.444
3cktYDPGag-Pol polyprotein3.4.23.160.444
3dk1G05Gag-Pol polyprotein3.4.23.160.444
3ggaGGWGag-Pol polyprotein/0.444
3ic9FADPutative dihydrolipoamide dehydrogenase/0.444
3m0wP77Protein S100-A4/0.444
3mxdK53Gag-Pol polyprotein3.4.23.160.444
3ow3SMYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.444
3pdqKC6Lysine-specific demethylase 4A1.14.110.444
3prsRITEndothiapepsin3.4.23.220.444
3qbhQBHBeta-secretase 13.4.23.460.444
3saa77FProtease/0.444
4bdiHAUSerine/threonine-protein kinase Chk22.7.11.10.444
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.444
4l17DNQGlutamate receptor 2/0.444
4x7wMVIMycinamicin III 3''-O-methyltransferase2.1.1.2370.444
1a940Q4Gag-Pol polyprotein3.4.23.160.443
1bygSTUTyrosine-protein kinase CSK/0.443
1ia9ANPTransient receptor potential cation channel subfamily M member 72.7.11.10.443
1k2b0Q4Gag-Pol polyprotein3.4.23.160.443
1lluNADAlcohol dehydrogenase/0.443
1lnyIMOAdenylosuccinate synthetase isozyme 1/0.443
1mtrPI6Gag-Pol polyprotein3.4.23.160.443
1t1sCBQ1-deoxy-D-xylulose 5-phosphate reductoisomerase1.1.1.2670.443
1typFADTrypanothione reductase1.8.1.120.443
2uzoC62Cyclin-dependent kinase 22.7.11.220.443
2uzwSS4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.443
2vo6M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.443
2z54AB1Gag-Pol polyprotein3.4.23.160.443
3antS82Bifunctional epoxide hydrolase 23.3.2.100.443
3dfcANPDeath-associated protein kinase 12.7.11.10.443
3eeySAMrRNA methylase/0.443
3gcvSS6Mitogen-activated protein kinase 14/0.443
3ha7B32Hydroxymycolate synthase MmaA42.1.10.443
3mxeK54Gag-Pol polyprotein3.4.23.160.443
3nu3478Gag-Pol polyprotein3.4.23.160.443
3pmy41LEndothiapepsin3.4.23.220.443
3s56ROCProtease/0.443
3st5G89Gag-Pol polyprotein3.4.23.160.443
3w18N13Aurora kinase A2.7.11.10.443
3w5rLOAVitamin D3 receptor/0.443
4dtbGMPAPH(2'')-Id/0.443
4i02CMPcAMP-activated global transcriptional regulator CRP/0.443
4njt017Protease/0.443
4opgFDAConserved Archaeal protein/0.443
4otwDB8Receptor tyrosine-protein kinase erbB-32.7.10.10.443
1c70L75Protease/0.442
1ebk0Q4Gag-Pol polyprotein3.4.23.160.442
1ec3MS3Gag-Pol polyprotein3.4.23.160.442
1w2xRCPAcetyl-CoA carboxylase/0.442
1yb5NAPQuinone oxidoreductase1.6.5.50.442
1zsf0ZSGag-Pol polyprotein3.4.23.160.442
2b00GCHPhospholipase A2, major isoenzyme3.1.1.40.442
2brgDFYSerine/threonine-protein kinase Chk12.7.11.10.442
2gstGPSGlutathione S-transferase Mu 12.5.1.180.442
2j62GSZO-GlcNAcase NagJ/0.442
2qd7065Gag-Pol polyprotein3.4.23.160.442
2upjU02Gag-Pol polyprotein3.4.23.160.442
2vo3M04cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.442
2w4jADPDeath-associated protein kinase 12.7.11.10.442
2ym2FADPhenylacetone monooxygenase1.14.13.920.442
2zjaACPATP-dependent DNA helicase Hel308/0.442
3gc9B45Mitogen-activated protein kinase 112.7.11.240.442
3ladFADDihydrolipoyl dehydrogenase/0.442
3qaaG04Gag-Pol polyprotein3.4.23.160.442
3qbfJHGGag-Pol polyprotein3.4.23.160.442
3sgx0FWDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.442
4dfg0JVGag-Pol polyprotein3.4.23.160.442
4h1m0YJProtein-tyrosine kinase 2-beta2.7.10.20.442
4j33FADKynurenine 3-monooxygenase/0.442
4j4bNAIUncharacterized protein/0.442
4nka2K7Fibroblast growth factor receptor 1/0.442
1bvgDMPGag-Pol polyprotein3.4.23.160.441
1difA85Gag-Pol polyprotein/0.441
1hb3SCVIsopenicillin N synthase1.21.3.10.441
1lvlFADDihydrolipoyl dehydrogenase1.8.1.40.441
1m17AQ4Epidermal growth factor receptor2.7.10.10.441
1me7RVPInosine-5'-monophosphate dehydrogenase/0.441
1meuDMPGag-Pol polyprotein3.4.23.160.441
1tcxIM1Gag-Pol polyprotein3.4.23.160.441
1zk7FADMercuric reductase1.16.1.10.441
2brbPFQSerine/threonine-protein kinase Chk12.7.11.10.441
2d4vNADIsocitrate dehydrogenase [NADP]/0.441
2hc0AB2Protease/0.441
2jb4A14Isopenicillin N synthase1.21.3.10.441
2p2i608Vascular endothelial growth factor receptor 22.7.10.10.441
2pmdGNPTranslation initiation factor 2 subunit gamma/0.441
2q5kAB1Protease/0.441
2q641UNGag-Pol polyprotein3.4.23.160.441
2r3wG3GGag-Pol polyprotein3.4.23.160.441
2rgjFADFlavin-containing monooxygenase/0.441
2zgzGNPPlasmid segregation protein ParM/0.441
3e92G6AMitogen-activated protein kinase 14/0.441
3evcSAHGenome polyprotein2.1.1.560.441
3nu4478Gag-Pol polyprotein3.4.23.160.441
3rnmFADDihydrolipoyl dehydrogenase, mitochondrial1.8.1.40.441
3s3tATPUniversal stress protein/0.441
3urhFADDihydrolipoyl dehydrogenase/0.441
4djqM86Pol polyprotein/0.441
4ftcH6KSerine/threonine-protein kinase Chk12.7.11.10.441
4h3qANPMitogen-activated protein kinase 12.7.11.240.441
4jqh1MFAlr2278 protein/0.441
4kip1R9Mitogen-activated protein kinase 14/0.441
4x81MVIMycinamicin III 3''-O-methyltransferase2.1.1.2370.441
4y380A9Endothiapepsin3.4.23.220.441
5fs7FADApoptosis-inducing factor 1, mitochondrial1.1.10.441
5fs8FADApoptosis-inducing factor 1, mitochondrial1.1.10.441
1bdrIM1Gag-Pol polyprotein3.4.23.160.440
1ey3DAKEnoyl-CoA hydratase, mitochondrial4.2.1.170.440
1fwkADPHomoserine kinase2.7.1.390.440
1hpxKNIGag-Pol polyprotein/0.440
1mrxK57Gag-Pol polyprotein3.4.23.160.440
1nvrSTUSerine/threonine-protein kinase Chk12.7.11.10.440
1zzrDP9Nitric oxide synthase, brain1.14.13.390.440
2c4cFAD[F-actin]-methionine sulfoxide oxidase MICAL11.14.130.440
2ooyATP5'-AMP-activated protein kinase subunit gamma/0.440
2p9kATPActin-related protein 2/0.440
2r5pMK1Gag-Pol polyprotein/0.440
2x3fAPCPantothenate synthetase/0.440
2zu8GDDMannosyl-3-phosphoglycerate synthase2.4.1.2170.440
3a1eACPProbable copper-exporting P-type ATPase A3.6.3.540.440
3cgcFADCoenzyme A disulfide reductase/0.440
3k4vROCGag-Pol polyprotein3.4.23.160.440
3m6gATPActin, alpha skeletal muscle/0.440
3ok9G52Gag-Pol polyprotein3.4.23.160.440
3pm0BHFCytochrome P450 1B1/0.440
3qrmNK7Gag-Pol polyprotein3.4.23.160.440
3sabF78Protease/0.440
3sacAF8Protease/0.440
3sw719KCyclin-dependent kinase 22.7.11.220.440
3zm5IGMUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase/0.440
4e5h0N8Polymerase acidic protein/0.440
4ft0HK9Serine/threonine-protein kinase Chk12.7.11.10.440
4gkh0J9Aminoglycoside 3'-phosphotransferase AphA1-IAB/0.440
4hla017Gag-Pol polyprotein3.4.23.160.440
4qq3XMPInosine-5'-monophosphate dehydrogenase/0.440
4zvnFADRibosyldihydronicotinamide dehydrogenase [quinone]/0.440
5d9j0N8Polymerase acidic protein/0.440
5f8fSFGPossible transcriptional regulatory protein/0.440